CN106620549A

CN106620549A - Medicine for treating jaundice hepatitis and preparation method of medicine

Info

Publication number: CN106620549A
Application number: CN201710172361.8A
Authority: CN
Inventors: 张腊梅
Original assignee: Individual
Current assignee: Individual
Priority date: 2017-03-22
Filing date: 2017-03-22
Publication date: 2017-05-10

Abstract

The invention discloses a medicine for treating jaundice hepatitis and a preparation method of the medicine. The medicine is mainly prepared from capillary wormwood herb, herba lysimachiae, herba patriniae, radix isatidis, corn stigma, fructus gardeniae, radix curcumae, radix et rhizoma rhei, lalang grass rhizome, agastache rugosus, radix scutellariae, fructus aurantii, radix bupleuri, radix salviae miltiorrhizae, radix clematidis, radix paeoniae alba and dried orange peel according to certain proportions by weight. The medicine provided by the invention has functions of induing diuresis and purging heat, calming liver and benefiting gallbladder, clearing heat and purging fire, promoting circulation of qi and relieving depression, cooling blood and removing stasis, soothing liver and rising yang; and the medicine, on treating the jaundice hepatitis, is rapid to take effects, good in curative effect and free from recurrence.

Description

It is a kind of to treat medicine of icteric hepatitis and preparation method thereof

Technical field

The present invention relates to a kind of treat medicine of icteric hepatitis and preparation method thereof, belong to the field of Chinese medicines.

Background technology

Icteric hepatitis is the hepatitis that the various causes of disease cause, while with skin and mucosa xanthochromia, serum bilirubin exceedes 17.1 μm of ol/L persons are referred to as icteric hepatitis.Icteric hepatitis is that jaundice is showed and whether abnormal level of serum total bilirubin rises based on whetheing there is Come what is defined, corresponding be anicteric hepatitis to height.Due to western medicine large side effects, therefore people are to effectively treatment There is great demand in the Chinese medicine of icteric hepatitis, up to now, it has not been found that with regard to the relevant report of the present invention.

The content of the invention

The present inventor have found effectively treatment jaundice finally according to the checking repeatedly of research and the clinical testing of theory of traditional Chinese medical science The medicine of type hepatitis, so as to complete the present invention.

It is an object of the invention to provide a kind of Chinese medicine composition of effectively treatment icteric hepatitis.

Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.

Medicine of the present invention is to select Artemisia capillaris, desmodium, Patrinia scaniosaefolia, Radix Isatidis, corn stigma, cape jasmine, root tuber of aromatic turmeric, rheum officinale, cogongrass Root, wrinkled giant hyssop, the root of large-flowered skullcap, Fructus Aurantii, radix bupleuri, the red sage root, the root of Chinese clematis, the root of herbaceous peony, dried orange peel, the bighead atractylodes rhizome, malt, reticulate millettia, rhizoma atractylodis, rhizoma alismatis carry out group Close what is prepared, cause each efficacy of drugs to produce synergy these drug regimens such that it is able to effectively treatment icteric hepatitis. Wherein its nature and flavor toil is because from Artemisia capillaris, cool, enter liver, spleen, bladder warp, the function of having clearing heat and promoting diuresis controls jaundice with damp-heat pathogen, Difficult urination, pruritus sore scabies.Its nature and flavor toil is because from desmodium, it is cool, there is heat-clearing, diuresis, antibechic is subsided a swelling, removing toxic substances Function, controls jaundice, and oedema, vesical calculus, malaria, lung carbuncle, cough is spitted blood, and stranguria with turbid discharge, under band, arthralgia due to wind-dampness, infantile malnutrition is shied Epilepsy, carbuncle swells, sore tinea, eczema.It is because that its nature and flavor is bitter from Patrinia scaniosaefolia, puts down, enter liver, stomach, large intestine channel have clearing heat and detoxicating, apocenosis is broken The function of the stasis of blood, controls acute appendicitis, diarrhea, leukorrhea with reddish discharge, postpartum stasis of blood, red eye, swell pain, carbuncle swells mange.It is because from Radix Isatidis Its nature and flavor is bitter, trembles with fear, and enter liver, stomach blood system have heat-clearing, removing toxic substances, the function of cool blood, controls influenza, epidemic meningitis, encephalitis, pneumonia, erysipelas, heat Poison sends out spot, and coma tells nosebleed, and pharynx is swollen, mumps, pinkeye, sore rash.It is because that its nature and flavor is sweet from corn stigma, puts down, there is diuresis, expels the heat-evil, Flat liver, the function of cholagogic controls nephritic dropsy, tinea pedis, icterohepatitis, hypertension, cholecystitis, gall stone, diabetes, nosebleed of spitting blood Blood, nasosinusitis, acute mastitis.It is because that its nature and flavor is bitter from cape jasmine, trembles with fear, enter the heart, liver, lung, stomach has heat-clearing, purging intense heat, the work(of cool blood Can, pyreticosis restlessness of asrhenia type and insomnia is controlled, jaundice, gonorrhoea is quenched one's thirst, hot eyes, pharyngalgia, is spitted blood, and bleeding from five sense organs or subcutaneous tissue, bloody flux, hematuria, pathopyretic ulcer is sprained Swell and ache.It is because that its nature and flavor is worked hard from root tuber of aromatic turmeric, cool, enter the heart, lung, Liver Channel have promoting the circulation of qi solution with the function of cool blood broken stasis of blood controls chest The all pains of abdomen side of body rib, the mistake heart is demented, pyreticosis coma, spits blood, bleeding from five sense organs or subcutaneous tissue, hematuria, blood strangury, women's vicarious menstruation, jaundice.It is because from rheum officinale Its nature and flavor is bitter, cold, enters stomach, large intestine, liver footpath, there is the poison that purges heat, and breaks stagnant, and the function of row hemostasis controls real heat constipation, and delirious speech is gone mad, Dyspepsia feeling of fullness, dysentery from the beginning of, tenesmus, stasis of blood menopause Bi ， lumps in the chest and abdomen, when the hot epidemic disease of row, sudden and violent swelling ophthalmalgia spits blood, bleeding from five sense organs or subcutaneous tissue, sun Huang, oedema, stranguria with turbid discharge is urinated red, large carbuncle pyogenic infections, furunculosis, burn.It is because that its nature and flavor is sweet, cold from cogongrass rhizome, enters lung, stomach, little Intestines Jing, there is cool blood, hemostasis, and heat-clearing, the function of diuresis controls pyreticosis polydipsia, spits blood, bleeding from five sense organs or subcutaneous tissue, and lung heat breathes heavily urgency, stomach energy hiccup, gonorrhoea, Difficult urination, oedema, jaundice.It is because that its nature and flavor is pungent from wrinkled giant hyssop, tepor enters lung, spleen, stomach, there is fast gas, and in, ward off dirty, The function of clearing damp, cure cold summer-heat and damp, fever and chills, headache, chest gastral cavity ruffian, vomiting is had loose bowels, malaria, dysentery, halitosis.From the root of large-flowered skullcap be because For its nature and flavor bitter cold, enter cardiopulmonary, courage, large intestine channel, have and rush down excess fire, except damp and hot, the function of arresting bleeding and miscarriage prevention, control high fever polydipsia, lung heat Cough.Its nature and flavor toil is because from Fructus Aurantii, it is cool, enter lung, spleen, large intestine channel, there is a relieving stagnant Qi, row phlegm, disappear long-pending function, controls chest diaphragm Phlegm is stagnant, the feeling of stuffiness in chest, coerces swollen, dyspepsia, and gas is vomitted inverse, weight, prolapse of the anus, the prolapse of uterus after diarrhea.It is because that its nature and flavor is bitter from radix bupleuri, Cool, enter liver, gallbladder channel are soothing the liver in having and inducing sweat, the function of rising Yang, control fevers and chills alternate, and fullness in the chest and hypochondriac pain, bitter taste is deaf, mesh of having a headache It is dizzy, malaria, lower sharp prolapse of the anus, irregular menstruation, metroptosis.It is because that its nature and flavor is bitter from the red sage root, tepor, enter the heart, Liver Channel have work Blood stasis eliminatings, calming heart and tranquilizing mind, apocenosis, the function of pain relieving controls angina pectoris, irregular menstruation, dysmenorrhoea, to close, metrorrhagia under band ， Disorder lumps in the abdomen, and product It is poly-, abdominal pain due to blood stasis, arthralgia, shock palpitation not sleep, malignant sore swollen drug.It is because that its nature and flavor is pungent salty from the root of Chinese clematis, temperature is poisonous, enters Bladder warp, there is wines used as antirheumatic, and degrading the channel, dissolving phlegm saliva, the function of dissipate the hypochondriac lump controls gout, stupid numbness, waist and knee crymodynia, tinea pedis, malaria ， Disorder Lump in the abdomen is gathered, lockjaw, tonsillitis, all bone sticking swallow.Its nature and flavor picric acid is because from the root of herbaceous peony, cool, enter liver, the spleen channel have blood-nourishing The cloudy function of receiving sweat is held back in soft liver, pain relieving in delaying, and controls chest and abdomen pain over the hypochondriac region, diarrhea dysentery abdominal pain, spontaneous sweating, fever due to yin deficiency, and menstruation is not Adjust, uterine bleeding, under band.It is because that its nature and flavor is bitter, pungent from dried orange peel, temperature, return lung, the spleen channel have regulating qi-flowing for strengthening spleen, eliminating dampness and eliminating phlegm work( Can, chest gastral cavity turgor is controlled, deficiency of food is vomited and diarrhoea, coughing with a lot of sputum.Its nature and flavor bitter sweet is because from the bighead atractylodes rhizome, temperature enters spleen, stomach, there is tonifying spleen, Beneficial stomach, eliminating dampness, and in function, control deficient QI of the spleen and stomach, do not feel like eating, the few gas of burnout is empty swollen, has loose bowels, and phlegm and retained fluid, oedema, jaundice is wet Numbness, difficult urination is dizzy, and spontaneous perspiration, nausea is uneasy.It is because that its nature and flavor is sweet from malt, tepor enters spleen, stomach, has and helps digestion, With in, the function of lower gas controls dyspepsia, and swollen distention and fullness in the abdomen, poor appetite, vomiting is had loose bowels, mammary swelling does not disappear.From reticulate millettia be because For its nature and flavor bitter sweet, temperature, enter the heart, the Jing of spleen two have the function of promoting blood circulation, relaxing muscles and tendons, control soreness of waist and knee joint, paralysis and numbness, irregular menstruation.Choosing It is because that its nature and flavor is worked hard with rhizoma atractylodis, temperature enters spleen, stomach, there is invigorating the spleen, and eliminating dampness, Xie Yu wards off dirty function, controls wet Sheng and be stranded spleen, it is tired Idle thermophilic sleeping, gastral cavity ruffian abdominal distension, poor appetite, vomiting is had loose bowels, dysentery, malaria, phlegm and retained fluid, oedema, when gas flu, wind-cold-dampness arthralgia, foot Impotence, yctalopia.It is because that its nature and flavor is sweet from rhizoma alismatis, trembles with fear, enter bladder warp, favourable water, excreting dampness, the function of expelling the heat-evil controls difficult urination, Oedema anus is expired, vomiting, rush down dysentery, phlegm and retained fluid, tinea pedis, gonorrhoea, hematuria.

Specific embodiment

The drug dose of instant component is also that inventor summarizes what is drawn through groping in a large number, and the consumption of each component is following heavy All there is preferable curative effect in the range of amount：

25-35 gram of Artemisia capillaris, 55-65 gram of desmodium, 25-35 gram of Patrinia scaniosaefolia, 25-35 gram of Radix Isatidis, 25-35 gram of corn stigma, cape jasmine 10-14 gram, 10-14 gram of root tuber of aromatic turmeric, 4-8 gram of rheum officinale, 25-35 gram of cogongrass rhizome, 5-15 gram of wrinkled giant hyssop, 20-30 gram of the root of large-flowered skullcap, Fructus Aurantii 15-25 Gram, 10-20 gram of radix bupleuri, 10-20 gram of the red sage root, 15-25 gram of the root of Chinese clematis, 5-15 gram of the root of herbaceous peony, 5-15 gram of dried orange peel, 5-15 gram of the bighead atractylodes rhizome, wheat 5-15 gram of bud, 10-14 gram of reticulate millettia, 5-15 gram of rhizoma atractylodis, 10-20 gram of rhizoma alismatis.

Preferably：

30 grams of Artemisia capillaris, 60 grams of desmodium, 30 grams of Patrinia scaniosaefolia, 30 grams of Radix Isatidis, 30 grams of corn stigma, 12 grams of cape jasmine, 12 grams of root tuber of aromatic turmeric, greatly It is yellow 6 grams, 30 grams of cogongrass rhizome, 10 grams of wrinkled giant hyssop, 25 grams of the root of large-flowered skullcap, 20 grams of Fructus Aurantii, 15 grams of radix bupleuri, 15 grams of the red sage root, 20 grams of the root of Chinese clematis, the root of herbaceous peony 10 grams, 10 grams of dried orange peel, 10 grams of the bighead atractylodes rhizome, 10 grams of malt, 12 grams of reticulate millettia, 10 grams of rhizoma atractylodis, 15 grams of rhizoma alismatis.

The preparation method of medicine of the present invention is as follows

First, get the raw materials ready

1st, Artemisia capillaris：Sieve, pick impurity, remove undesirable root, pulverize, after weeding out net spare；

2nd, desmodium：Net impurity is picked, grey bits are weeded out, is dried；

3rd, Patrinia scaniosaefolia：Crude drug is taken, impurity is removed, with Water spray, is slightly dried in the air, segment is dried；

4th, Radix Isatidis：Net impurity is picked, is cleaned, run through, cut into slices, dried；

5th, corn stigma：Crude drug is taken, impurity is removed, grey bits are weeded out；

6th, cape jasmine：Grey bits are weeded out, impurity is picked, is pulverized and is sieved or cut off two ends；

7th, root tuber of aromatic turmeric：It is soaked in water, cleans, pull solarization out and dry in the air, run through, cut into slices, dries；

8th, rheum officinale：Net impurity is picked, size stepping, vexed profit to inside and outside humidity is uniform, cuts into slices or is cut into small pieces, dries；

9th, cogongrass rhizome：Net impurity is picked, is cleaned, micro- profit, segment is dried, net chip of winnowing with a dustpan；

10th, wrinkled giant hyssop：Impurity is picked, undesirable root and old stem is removed, first leaf is taken and is separately put, stem is run through with water, segment, is dried, then With leaf and even；

11st, the root of large-flowered skullcap：Impurity is picked, residual stem is removed, is infiltrated or is put slightly to soak in boiling water with cold water and pull out, cut into slices, dried；

12nd, Fructus Aurantii：Flesh, core are removed, edulcoration slightly soaks, pulls out, softens, pinching doubling with hand, section is dried；

13rd, radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, is pulled out, section in time, dries immediately after running through；

14th, the red sage root：Net impurity is picked, rhizome is removed, is cleaned, pulled out, cut into slices after running through, dried；

15th, the root of Chinese clematis：Net impurity is picked, residual stem is removed, is soaked in water, pulled out and run through, segment is dried；

16th, the root of herbaceous peony：Impurity is picked, separates size, be soaked in water to eighty per cant thoroughly, pulled out, solarization is dried in the air, moisten uniform to inside and outside humidity, Section, is dried；

17th, dried orange peel：Crude drug is taken, the pericarp of impurity and blackening is removed, wash quickly is net, softens, chopping, dries or low temperature drying, Weed out grey bits；

18th, the bighead atractylodes rhizome：Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried；

19th, malt：Take malt put it is micro- in pot fry to yellow, taking-up is cooled；

20th, reticulate millettia：Run through with water, cut into slices, or cut into slices while hot after steaming is soft, dried；

21st, rhizoma atractylodis：Impurity is picked, with bubble to seven, most probably thoroughly, is pulled out, cut into slices after running through, dried；

22nd, rhizoma alismatis：Impurity is picked, size stepping is soaked in water to eighty per cant thoroughly, pulls out, shines cool, vexed to moisten uniform to inside and outside humidity, Section, dries.

2nd, prepare

1st, by the Artemisia capillaris of the weight, desmodium, Patrinia scaniosaefolia, Radix Isatidis, corn stigma, cape jasmine, root tuber of aromatic turmeric, rheum officinale, cogongrass rhizome, the leaves of pulse plants Perfume, the root of large-flowered skullcap, Fructus Aurantii, radix bupleuri, the red sage root, the root of Chinese clematis, the root of herbaceous peony, dried orange peel, the bighead atractylodes rhizome, malt, reticulate millettia, rhizoma atractylodis, rhizoma alismatis are put into appearance of boiling medicine In device, add water 8 times and measure, after soaking 120 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, filter to obtain decoction for the first time Liquid, first time decoction liquor is poured into container；

2nd, the dregs of a decoction of filtration are added water 6 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；

3rd, will decoction liquor mixing and stirring twice, be divided into 3 doses and take.

Corn stigma has diuresis in prescription, expels the heat-evil, flat liver, and the function of cholagogic is monarch drug in a prescription；Cape jasmine has a heat-clearing, purging intense heat, cool blood Function；Root tuber of aromatic turmeric has promoting the circulation of qi solution with, the function of cool blood broken stasis of blood, and the two is ministerial drug, and three taste medicines play diuresis and expel the heat-evil jointly, flat liver profit Courage, clearing heat-fire, promoting the circulation of qi solution is with comprehensively the effect of cool blood broken stasis of blood, treatment icteric hepatitis effect, and is expelled the heat-evil with diuresis, flat liver Cholagogic, can effect a permanent cure based on clearing heat-fire, soothing the liver in radix bupleuri has and induces sweat, and the function of rising Yang is adjutant, and the bighead atractylodes rhizome has a tonifying spleen, beneficial stomach, Eliminating dampness, and in function to make medicine, all medicines are to take stopgap measures with being left.

There is medicine of the present invention diuresis to expel the heat-evil, flat liver cholagogic, clearing heat-fire, promoting the circulation of qi solution with, cool blood broken stasis of blood, soothing the liver rising Yang Function, for treating icteric hepatitis, short treating period, instant effect, non-relapse after healing.

The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples are including this The animal toxicity test report of bright medicine and clinical observation on the therapeutic effect data.

The animal toxicity test report of [test example 1] medicine of the present invention：

Rabbit 30 is taken, male and female dual-purpose, 2.0-2.5kg of body weight is divided to two groups, and 15 per group, one of which is overdose test Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is 10ml/kg, and administering mode is given for administration by gavage Medicine, twice daily, serve on 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is without bad Toxic and side effect.

The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention

1st, physical data

Accept icteric hepatitis out-patient totally 29 for medical treatment.

2nd, diagnostic criteria

Classical symptom be the last from days that occurs at no distant date it is weak, detest greasy, nauseous etc., severe patient may occur in which it is extremely weak, Substantially etc., or even there is rapidly more than II degree hepatic encephalopathy in anorexia, vomiting.Sign has hepatomegaly and has tenderness, hepatic region to kowtow Pain is hit, some patientss there can be slight splenomegaly.Laboratory examination blood occurs the performance that liver function declines, and such as transaminase is raised Deng.

3rd, treatment method

From above-mentioned medicament, take to patient, each take 1 dose, it is early, middle and late daily respectively to take 1 time, it is within 15 days a course for the treatment of, even It is continuous to take 3 courses for the treatment of.

4th, efficacy assessment standard

It is effective：Icteric hepatitis symptom disappears, and recovers normal, recovery from illness；

Take a turn for the better：Icteric hepatitis symptom is clearly better, weak, detest oil, nausea and mitigate, and liver function progressively recovers normal；

It is invalid：Improvement standard person is not reached.

5th, treatment results（See the table below）

In above-mentioned treatment, with drug therapy icteric hepatitis patient 29 of the present invention, as a result effective 24, obvious effective rate is 82.8%, take a turn for the better 3, improvement rate is 10.3%, and invalid 2, total effective rate is 93.1%.

Claims

1. a kind of medicine for treating icteric hepatitis, it is characterised in that：It is made up of the bulk drug in following weight range：

2. medicine according to claim 1, wherein the consumption of each bulk drug is：

3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps：

（One）Get the raw materials ready

（1）Artemisia capillaris：Sieve, pick impurity, remove undesirable root, pulverize, after weeding out net spare；

（2）Desmodium：Net impurity is picked, grey bits are weeded out, is dried；

（3）Patrinia scaniosaefolia：Crude drug is taken, impurity is removed, with Water spray, is slightly dried in the air, segment is dried；

（4）Radix Isatidis：Net impurity is picked, is cleaned, run through, cut into slices, dried；

（5）Corn stigma：Crude drug is taken, impurity is removed, grey bits are weeded out；

（6）Cape jasmine：Grey bits are weeded out, impurity is picked, is pulverized and is sieved or cut off two ends；

（7）Root tuber of aromatic turmeric：It is soaked in water, cleans, pull solarization out and dry in the air, run through, cut into slices, dries；

（8）Rheum officinale：Net impurity is picked, size stepping, vexed profit to inside and outside humidity is uniform, cuts into slices or is cut into small pieces, dries；

（9）Cogongrass rhizome：Net impurity is picked, is cleaned, micro- profit, segment is dried, net chip of winnowing with a dustpan；

（10）Wrinkled giant hyssop：Impurity is picked, undesirable root and old stem is removed, first leaf is taken and is separately put, stem is run through with water, segment, is dried, then With leaf and even；

（11）The root of large-flowered skullcap：Impurity is picked, residual stem is removed, is infiltrated or is put slightly to soak in boiling water with cold water and pull out, cut into slices, dried；

（12）Fructus Aurantii：Flesh, core are removed, edulcoration slightly soaks, pulls out, softens, pinching doubling with hand, section is dried；

（13）Radix bupleuri：Impurity is picked, residual stem is removed, silt is cleaned, is pulled out, section in time, dries immediately after running through；

（14）The red sage root：Net impurity is picked, rhizome is removed, is cleaned, pulled out, cut into slices after running through, dried；

（15）The root of Chinese clematis：Net impurity is picked, residual stem is removed, is soaked in water, pulled out and run through, segment is dried；

（16）The root of herbaceous peony：Impurity is picked, separates size, be soaked in water to eighty per cant thoroughly, pulled out, solarization is dried in the air, moisten uniform to inside and outside humidity, Section, is dried；

（17）Dried orange peel：Crude drug is taken, the pericarp of impurity and blackening is removed, wash quickly is net, softens, chopping, dries or low temperature drying, Weed out grey bits；

（18）The bighead atractylodes rhizome：Net impurity is picked, is soaked in water, pulled out after bubble, run through, cut into slices, dried；

（19）Malt：Take malt put it is micro- in pot fry to yellow, taking-up is cooled；

（20）Reticulate millettia：Run through with water, cut into slices, or cut into slices while hot after steaming is soft, dried；

（21）Rhizoma atractylodis：Impurity is picked, with bubble to seven, most probably thoroughly, is pulled out, cut into slices after running through, dried；

（22）Rhizoma alismatis：Impurity is picked, size stepping is soaked in water to eighty per cant thoroughly, pulls out, shines cool, vexed to moisten uniform to inside and outside humidity, Section, dries；

（Two）Prepare

（1）By the Artemisia capillaris of the weight, desmodium, Patrinia scaniosaefolia, Radix Isatidis, corn stigma, cape jasmine, root tuber of aromatic turmeric, rheum officinale, cogongrass rhizome, the leaves of pulse plants Perfume, the root of large-flowered skullcap, Fructus Aurantii, radix bupleuri, the red sage root, the root of Chinese clematis, the root of herbaceous peony, dried orange peel, the bighead atractylodes rhizome, malt, reticulate millettia, rhizoma atractylodis, rhizoma alismatis are put into appearance of boiling medicine In device, add water 8 times and measure, after soaking 120 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, filter to obtain decoction for the first time Liquid, first time decoction liquor is poured into container；

（2）The dregs of a decoction of filtration are added water 6 times and is measured, boiled by intense fire, then with being cooked by slow fire 20 minutes, filter to obtain second decoction liquor；

（3）Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 3 doses and is taken.