CN106620085A - Tibetan medicine composition for treating diabetes and preparation method of Tibetan medicine composition - Google Patents
Tibetan medicine composition for treating diabetes and preparation method of Tibetan medicine composition Download PDFInfo
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- A61K36/88—Liliopsida (monocotyledons)
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- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
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- A61K2236/30—Extraction of the material
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- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/333—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using mixed solvents, e.g. 70% EtOH
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- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention relates to Tibetan medicine composition for treating diabetes and a preparation method of the Tibetan medicine composition. The composition is prepared from flowers of scindapsus aureus, sibiraea augustata and crocus sativus and in the form of capsules, granules, tablets or pills prepared by using a pharmaceutically acceptable carrier or excipient. The composition has the effects of clearing heat, removing toxins, dispersing stagnation and dredging collaterals and is applicable to patients suffered from impaired glucose regulation and early diabetes patients. Preliminary experiment research indicates that the composition can lower blood glucose, reduce insulin resistance, increase sensitivity of insulin, protect beta cell functions, reduce serum total cholesterol and serum triglyceride and has no toxic and side effects. Clinical research indicates that the composition can reduce fasting blood glucose and postprandial blood glucose and has no toxic and side effects.
Description
First, technical field
The present invention relates to one kind treats diabetes Tibetan medicinal composition and preparation method thereof.
2nd, background technology
Diabetes are common clinical, frequently-occurring disease.Development and Living consumption with countries in the world social economies
Improve, the incidence of disease and illness rate of diabetes are raised year by year, it has also become threaten the global great public health problem of people's health,
So as to cause national governments, hygiene department and the concern and attention of numerous medical personnels.In recent years, diabetes mellitus in China is ill
Number is increased rapidly, and multinomial research shows, China's maturity-onset diabetes illness rate from 0.67%, 2.5% in 1994 in 1980,
3.21% in 1996, has increased to 11.6% in 9.7% in 2007, or even 2010.Internationally famous medical science in 2010
Periodical《New England Journal of Medicine》" diabetes mellitus in China and metabolic syndrome are studied to deliver diabetology branch of Chinese Medical Association
Result of the group " with regard to China's diabetes prevalence investigation.The investigation shows, masculinity and femininity glycosuria in more than 20 years old crowd of China
, respectively up to 10.6% and 8.8%, overall illness rate is up to 9.7% for the illness rate of disease.The illness rate of same period prediabetes is up to
15.5%.The reckoning made according to current investigation result shows the total patient of diabetes patient number of China up to 92,400,000, before diabetes
Phase number is up to 1.48 hundred million.China has surmounted India becomes the most country of global diabetes patient.According to WHO, it is expected that to the year two thousand thirty sugar
The death rate that urine disease causes will double, and this will produce tremendous influence to personal, family or even country, and cause very big
Burden on society.WHO estimates that, in 2006-2015 ten years, diabetes will bring 558,000,000,000 dollars of economic damage to China
Lose.Control diabetes and its complication are the great public health problems of global concern.
Tibet is the district occurred frequently of diabetes.The dietary structure of Tibetan of this area masses with high heat, high protein, it is higher fatty acid,
Based on low cellulose, high sodium salt and low-carb.Reflect from nutrition survey table, the intake of fat in Tibetan's masses' diet
Amount is relatively more, and animal oil 72g is averagely taken in for each person every day, is mainly derived from butter, beef and mutton and internal organ group food, and someone is very
Can drink into buttered tea 4000ml to one day.With deepening continuously for research, different Fatty acid components are sent out diabetes B in food
The impact of disease is taken seriously more and more, the fat intake of Tibet Tibetan populations mainly based on saturated fatty acid, epidemic disease
Learn research and show higher unsaturated fatty acid intake and hyperinsulinemia positive correlation, this has direct relation with the morbidity of diabetes.
According to the mid-aged population diabetes prevalence scalping of rural areas of Lhasa City Tibetan, the method pair in the generaI investigation of resident concentration zones is adopted within 2003
4851 Tibetan's mid-aged populations carry out dietary structure, physical activity questionnaire investigation and empty stomach, 2h-plasma glucose and (or) oral
Glucose tolerance is checked.As a result show, rural areas of Lhasa City Tibetan mid-aged population diabetes prevalence is 6.8%, IGT
For 11.6%.
China's tradition Tibetanmedicine have accumulated rich experience to the understanding and treatment aspect of diabetes.Described in modern medicine
Diabetes should belong to the Jing Nisaku disease categories of traditional Tibetan medicine.There is the meaning of frequent micturition in the Buddhist nun's Tibetan language of capital, be due to fat and Baconic's mistake
Contain, fail the elite such as liter Huawei's blood marrow muscle, but flow directly into bladder, so as to cause hypourocrinia urine muddiness dripping not
A kind of disconnected urine disease being characterized；Sa Ku has the meaning for consuming muddy thing in Tibetan language.Many Tibetan medicine's ancient books are sick to Jing Nisaku
Cause of disease Symptomatic classification and the aspect such as treatment have more discussion.With regard to the cause of disease of diabetes,《Four doctor's allusion quotations》Record road：" disease
Because being because the food of salty, sweet, sour overfeeding, taste and property weight, or sombre ground is occupy long, (water and soil is trembled with fear to cause physical efficiency Baconic
Property) material increasing contain, fall into bladder turn to urine it is therefore.”《Eight essences will be released originally》It is also considered as：" this disease is diet, Baconic, fat
Fat (can not be converted into the precise and tiny of nutrition body) turns to urine, so forming diabetes." it follows that excessively diet it is sweet, sour,
Saline taste, it is greasy, be difficult to digestibility weight the food wine that for example dough powder, the flour of cool property cereal, Xingu are made, many hails produced
The food such as millet, sucrose, sugarcane bar and cheese, add that sitting is motionless, bed is uncomfortable and cause the reasons such as poor sleep all can cause
Urinary tract is not smooth, urine product bladder, causes urine muddy and sick.Accordingly, it can be said that the morbidity of diabetes is often by causing training in vivo
What the improper diet and daily life that root and fat increasing are contained was caused.Tibetan medicine has more than 20 kinds to the prescription of diabetes.Taken according to different syndromes
With different agents, " Baconic " type can use hot millet, barberry, three fruits, seed of Cortex Holarrhenae Antidysentericae, caudate sweetleaf leaf, pseudo-ginseng, stichopus japonicus, common embelia fruit, day
Southern Star decoct soup is made powder and is taken after mixing with liquid with honey；" red bar " type can with the stem of noble dendrobium, caudate sweetleaf leaf, santal, myrobalan, wide muscle rattan, emblic,
Barberry is hidden, horse pocket tinkling of pieces of jade decoct soup or make powder and be taken after mixing with liquid with honey；" grand " type can be co-mulled and made into three fruits, Chinese pine, barberry root, with shortcake
Oil or meat soup take.Tibetan medicine modern times compound treatment diabetes：Plateau plant epipremnum aureum flower, black fruit lyceum, the Radix Astragali, myrobalan, emblic,
Spoon leaf Ji head grass, the fruit of Chinese magnoliavine, flower anchor, turnip, sea-buckthorn, Rhodida plant, river deer wheatgrass platymiscium etc. are Tibetan's folk tradition
Hypoglycemic plant.In recent years, it is flavones Alkaloid by the main component of modern means of science and technology analysis tool blood sugar reducing function therein
Polysaccharide tannin etc..
At present, Tibetan medicine and pharmacology treatment diabetes are dialectical using parting mostly, lack prescribed preparation, it would be highly desirable to using modern pharmaceutical skill
Art exploitation treatment diabetes innovation Tibetan medicine.The total storehouse of Chinese knowledge knowledge network (CNKI) data in literature of Jing retrievals, finds altogether and " diabetes "
Related " Tibetan medicine " Research Literature 17, does not find the prescribed preparation for getting the Green Light.Chinese knowledge knowledge network (CNKI) the patent number of Jing retrievals
According to total storehouse, " Tibetan medicine " Patent Application Publication 12 related to " diabetes " is found altogether, do not find the prescribed preparation for getting the Green Light.
The present invention proposes that " wet poison stasis of blood network " is to cause Jing Nisaku sick with Tibetan medicine's theoretical " fat and Baconic cross Sheng " to instruct
There is the crucial interpretation of the cause, onset and process of an illness of development, for this purpose, proposing " clearing heat and detoxicating, disperse blood stasis and dredge collateral " new rules for the treatment of, hidden with treating diabetes on prescription
Based on medicine classical prescription, using modern scientific method and pharmaceutical technology technology screening optimization prescription, develop treatment diabetes and hide
Drug composition, receives in clinic and has treated effect.This product prescription (epipremnum aureum flower, willow tea, safflower) Jing looks into newly (report number：
CHX2016148) do not find to be delivered with main flavour of a drug identical prescription and patent is declared, therefore, the present invention possesses novelty, wound
New property and practicality.
3rd, the content of the invention
It is an object of the invention to provide treatment diabetes Tibetan medicinal composition of a kind of determined curative effect and preparation method thereof, fits
For Impaired Glucose Regulation and diabetes early stage patient.
Technical scheme：One kind treats diabetes Tibetan medicinal composition, is made up of epipremnum aureum flower, willow tea, safflower, its
It is characterised as the medicament being prepared from by following raw material compositions and weight proportion：Epipremnum aureum spend 10～40 parts, 10～30 parts of willow tea,
3～20 parts of safflower；Preferred weight ratio range of the present invention is：Epipremnum aureum spend 12～30 parts, 8～20 parts of willow tea, safflower 5～10
Part；Best weight ratio scope of the present invention is：Epipremnum aureum spend 15 parts, 10 parts of willow tea, 5 parts of safflower.
A kind of preparation method for treating diabetes Tibetan medicinal composition, it is characterised in that it is using following conventional manner technique
Made by medicament, including following pill, granule, capsule, tablets and other formulations.Its preparation method is according to the following steps：By formula
Measure epipremnum aureum flower, willow tea, safflower medicinal material, first take willow tea, epipremnum aureum flower Jia 10～12 times of amount decoctings boil 2 times, 1 hour every time, pan-fried
Liquid is filtered, and it is 1.05～1.10 (50 DEG C) that filtrate merging is concentrated into relative density, standby；Safflower is taken again plus 8～10 times of amounts
70% alcohol reflux is extracted 2 times, and 1 hour every time, decompression recycling ethanol was concentrated into relative density 1.05～1.10 (50 DEG C)；Close
And concentrate twice, appropriate dextrin is added, mix, fine powder is dry, pulverize into, particle is made, it is dried, add Steviosin appropriate,
Mix, make particle, be drying to obtain.
Wherein, finished dosage forms be using pharmaceutically acceptable carrier or any formulation made by excipient, such as granule,
Tablet, capsule, pill etc..
It is an advantage of the current invention that prescription is unique, determined curative effect, safety, economy, without obvious toxic-side effects, with " heat-clearing
The effect of removing toxic substances, disperse blood stasis and dredge collateral ", it is adaptable to which Impaired Glucose Regulation and diabetes early stage patient are taken.Preliminary experiment research shows
The present invention has to be reduced blood sugar, mitigates insulin resistance, increases the sensitiveness of insulin, protects β cell functions, reduces serum total
Cholesterol and serum levels of triglyceride, have no toxic and side effect.Clinical research shows that the present invention can reduce fasting blood-glucose and after the meal blood
Sugar, has no toxic and side effect.Clinical study results are as follows：
Clinical observation of the thing of the present invention to Impaired Glucose Regulation
1st, object and method：(1) diagnostic criteria (reference《Diabetes mellitus in China treatment guidelines》2004)：Impaired glucose tolerance
(IGT)：Fasting blood-glucose (FPG) value ＜ 7.0mmol/L (126mg/dl), and blood sugar (2HPG) >=7.8mmol/L when 2 after load
(140mg/dl), ＜ 11.1mmol/L (200mg/dl).(2) case standard is included：Doctor trained in Western medicine is diagnosed as IGT person, age
Between 40～65 years old.It is that blood sugar, still in abnormal ranges person, accepts altogether 36 sugar for medical treatment resistance to Jing after diet adds motion to intervene to include case
Amount patients with abnormal.Plus 1 bag every time of thing of the present invention (is made up, every bag of 3g of epipremnum aureum flower, willow tea, safflower.), 3 times a day, 3 months
For a course for the treatment of.(5) MAIN OUTCOME MEASURES：Fasting blood-glucose (FPG), after the meal 2 hours blood glucoses (2hPG), glycosylated hemoglobin
(HbA1C), plasma insulin (FINS).
2nd, efficacy evaluation：(1) control：Blood sugar and fasting blood-glucose recover normal when 2 after carbohydrate tolerance test clothes sugar；(2) have
Effect：Blood sugar or fasting blood-glucose are reduced when 2 after carbohydrate tolerance test clothes sugar, but do not recover normal；(3) it is invalid：Carbohydrate tolerance test clothes sugar
Afterwards 2 when blood sugar and fasting blood-glucose without improve or raise.
3rd, clinical observation result
FPG, 2hPG, HbA before and after the treatment of table 11c, FINS comparison
Note：Itself compare before and after △ treatments, P ＜ 0.05.
From table 1, after treating 2 months, significant difference (p ＜ 0.05) before and after FPG, 2hPG treatment illustrates thing of the present invention
Play the role of preferably to reduce empty stomach and postprandial hyperglycemia；Significant difference result (p before and after treatment group's Fasting insulin level treatment
＜ 0.05), show that thing of the present invention is improved insulin sensitivity effect.
4th, specific embodiment
Below the present invention is elaborated with specific embodiment：
Embodiment 1：
Raw material is weighed according to following proportioning：Epipremnum aureum spend 15 parts, 10 parts of willow tea, 5 parts of safflower.
Preparation method：Epipremnum aureum flower, willow tea, safflower medicinal material are measured by formula, willow tea, epipremnum aureum flower is first taken and Jia 10～12 times of amounts
Decocting is boiled 2 times, and 1 hour every time, decocting liquid was filtered, and it is 1.05～1.10 (50 DEG C) that filtrate merging is concentrated into relative density, standby；Again
Take safflower plus 8～10 times amount 70% alcohol refluxs extract 2 times, 1 hour every time, decompression recycling ethanol was concentrated into relative density
1.05～1.10 (50 DEG C)；Merge concentrate twice, add appropriate dextrin, mix, dry, pulverize into fine powder, make particle, do
It is dry, add Steviosin appropriate, mix, particle is made, it is drying to obtain.
Embodiment 2：
Raw material is weighed according to following proportioning：Epipremnum aureum spend 20 parts, 15 parts of willow tea, 8 parts of safflower.
Preparation method：Epipremnum aureum flower, willow tea, safflower medicinal material are measured by formula, willow tea, epipremnum aureum flower is first taken and Jia 10～12 times of amounts
Decocting is boiled 2 times, and 1 hour every time, decocting liquid was filtered, and it is 1.05～1.10 (50 DEG C) that filtrate merging is concentrated into relative density, standby；Again
Take safflower plus 8～10 times amount 70% alcohol refluxs extract 2 times, 1 hour every time, decompression recycling ethanol was concentrated into relative density
1.05～1.10 (50 DEG C)；Merge concentrate twice, add appropriate dextrin, mix, dry, pulverize into fine powder, make particle, do
It is dry, add Steviosin appropriate, mix, particle is made, it is drying to obtain.
Embodiment 3：
Raw material is weighed according to following proportioning：Epipremnum aureum spend 35 parts, 20 parts of willow tea, 10 parts of safflower.
Preparation method：Epipremnum aureum flower, willow tea, safflower medicinal material are measured by formula, willow tea, epipremnum aureum flower is first taken and Jia 10～12 times of amounts
Decocting is boiled 2 times, and 1 hour every time, decocting liquid was filtered, and it is 1.05～1.10 (50 DEG C) that filtrate merging is concentrated into relative density, standby；Again
Take safflower plus 8～10 times amount 70% alcohol refluxs extract 2 times, 1 hour every time, decompression recycling ethanol was concentrated into relative density
1.05～1.10 (50 DEG C)；Merge concentrate twice, add appropriate dextrin, mix, dry, pulverize into fine powder, make particle, do
It is dry, add Steviosin appropriate, mix, particle is made, it is drying to obtain.
Claims (5)
1. one kind treats diabetes Tibetan medicinal composition, it is characterised in that be the medicament being prepared from by following raw material weight proportioning of soup processed：
Epipremnum aureum spend 10～40 parts, 10～30 parts of willow tea, 3～20 parts of safflower.
2. one kind as claimed in claim 1 treats diabetes Tibetan medicinal composition, and the weight proportion of its raw material is：Epipremnum aureum spends 12～
30 parts, 8～20 parts of willow tea, 5～10 parts of safflower.
3. the one kind as described in claim 1 or one of 2 treats diabetes Tibetan medicinal composition, and the weight proportion of its raw material is：It is green
15 parts of trailing plants, 10 parts of willow tea, 5 parts of safflower.
4. a kind of preparation method for treating diabetes Tibetan medicinal composition as described in claim 1,2 or one of 3, it is characterised in that
It is, by above-mentioned raw materials combination matching, to be prepared by following steps：Epipremnum aureum flower, willow tea, safflower medicinal material are measured by formula, is first taken
Willow tea, epipremnum aureum flower Jia 10～12 times of amount decoctings boil 2 times, 1 hour every time, decocting liquid filtration, filtrate merging be concentrated into 50 DEG C it is relatively close
Spend for 1.05～1.10, it is standby；Take again safflower plus 8～10 times amount 70% alcohol refluxs extract 2 times, 1 hour every time, reduce pressure back
Ethanol is received, 50 DEG C of relative densities 1.05～1.10 are concentrated into；Merge concentrate twice, add appropriate dextrin, mix, be dried, powder
Fine powder is broken into, particle is made, is dried, add Steviosin appropriate, mixed, make particle, be drying to obtain.
5. a kind of preparation method for treating diabetes Tibetan medicinal composition as claimed in claim 4, it is characterised in that finished dosage forms
It is using pharmaceutically acceptable carrier or granule, tablet, capsule or pill made by excipient.
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Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1899472A (en) * | 2006-07-04 | 2007-01-24 | 洛嘎 | Night oral administration Tibet medicine for treating diabetes and its preparing method |
| CN104611184A (en) * | 2015-02-28 | 2015-05-13 | 崔子扬 | Nutritional jaboticaba fruit vinegar and preparation method thereof |
| CN104784381A (en) * | 2015-05-07 | 2015-07-22 | 设孜丹增群佩 | Compounded Tibetan medicine for treating hypertension and diabetes and lowering blood fat |
-
2016
- 2016-10-28 CN CN201610922905.3A patent/CN106620085A/en active Pending
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1899472A (en) * | 2006-07-04 | 2007-01-24 | 洛嘎 | Night oral administration Tibet medicine for treating diabetes and its preparing method |
| CN104611184A (en) * | 2015-02-28 | 2015-05-13 | 崔子扬 | Nutritional jaboticaba fruit vinegar and preparation method thereof |
| CN104784381A (en) * | 2015-05-07 | 2015-07-22 | 设孜丹增群佩 | Compounded Tibetan medicine for treating hypertension and diabetes and lowering blood fat |
Non-Patent Citations (8)
| Title |
|---|
| 乐农网: "绿萝花和藏红花可以一起冲泡吗", 《WWW.LENW.CN/NONGYEBAIKE/SHOW-65005.HTML》 * |
| 北京市卫生局: "《中草药制剂技术》", 31 December 1978, 化学工业出版社 * |
| 卫阳飞，等: "藏药柳茶提取物对四氧嘧啶糖尿病小鼠降糖作用的研究", 《时珍国医国药》 * |
| 曾艺玲，等: "藏药绿萝花超临界萃取工艺优化及降血糖作用研究", 《中国民族民间医药》 * |
| 李梅: "复方绿柳颗粒改善2型糖尿病ZDF大鼠胰岛素抵抗作用及机制研究", 《中国博士学位论文全文数据库医药卫生科技辑》 * |
| 王艺润，等: "藏医藏药对糖尿病的认识与治疗", 《中国民族医药杂志》 * |
| 王赛，等: "藏药绿萝花对高血糖小鼠模型的治疗试验", 《动物医学进展》 * |
| 陈发胜，等: "红花注射液治疗糖尿病周围神经病变机制初探", 《河北中医》 * |
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Address after: 850000, 24 hot road, Tibet, Lhasa, attached 10 Applicant after: Tibet University of Tibetan Medicine Address before: 850000, 24 hot road, Tibet, Lhasa, attached 10 Applicant before: TIBETAN TRADITIONAL MEDICAL College |
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Application publication date: 20170510 |