CN106620081A - Buccal tablet for treating oral ulcer - Google Patents

Buccal tablet for treating oral ulcer Download PDF

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Publication number
CN106620081A
CN106620081A CN201710150459.3A CN201710150459A CN106620081A CN 106620081 A CN106620081 A CN 106620081A CN 201710150459 A CN201710150459 A CN 201710150459A CN 106620081 A CN106620081 A CN 106620081A
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Prior art keywords
parts
canker sore
lozenge
alum
borneol
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CN201710150459.3A
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闫坤
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Sichuan Pharmaceutical Technology Co Ltd
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Sichuan Pharmaceutical Technology Co Ltd
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Priority to CN201710150459.3A priority Critical patent/CN106620081A/en
Publication of CN106620081A publication Critical patent/CN106620081A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • A61K33/06Aluminium, calcium or magnesium; Compounds thereof, e.g. clay
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/045Hydroxy compounds, e.g. alcohols; Salts thereof, e.g. alcoholates
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/534Mentha (mint)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0053Mouth and digestive tract, i.e. intraoral and peroral administration
    • A61K9/0056Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients
    • A61K9/2022Organic macromolecular compounds
    • A61K9/2031Organic macromolecular compounds obtained otherwise than by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyethylene glycol, polyethylene oxide, poloxamers
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Mycology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Inorganic Chemistry (AREA)
  • Zoology (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a buccal tablet for treating oral ulcer. The buccal tablet is prepared from the following components, by mass, 20 to 32 parts of alum, 5 to 8 parts of borneol, 15 to 20 parts of honeysuckle flower, 10 to 15 parts of cape jasmine, 12 to 18 parts of mint, 10 to 16 parts of puffball fruiting body, 6 to 12 parts of grosvenor momordica fruit, 10 to 14 parts of aloe, 14 to 20 parts of taxillus, 30 to 45 parts of a diluent and 8 to 12 parts of a binder. The buccal tablet can directly act on an affected part, alleviates the pain of a patient, rapidly cures oral ulcer, is free of side-effect and can prevent repeated attack by oral ulcer.

Description

A kind of lozenge for treating canker sore
Technical field
The present invention relates to dental ulcer treatment field, and in particular to a kind of lozenge for treating canker sore.
Background technology
Canker sore is commonly called as " aphtha ", is a kind of common ulcerative damages illness for betiding mucous membrane of mouth, is more common in The positions such as lip inner side, tongue, tongue abdomen, cheek mucous membrane, vestibular ditch, soft palate, the mucous membrane at these positions lack keratinization layer or angling compared with Difference.Tongue ulcer refers to and betides tongue, the canker sore of tongue belly position.Sharp ache when canker sore is shown effect, local cusalgia is bright Aobvious, severe patient can also affect diet, speak, and very big inconvenience is caused to daily life;Can concurrently halitosis, chronic pharyngitis, constipation, head The constitutional symptoms such as bitterly, dizzy, nauseous, weak, irritated, heating, enlargement of lymph nodes.
At present treatment canker sore has the methods such as antiphlogistic for oral administration, mealy medicine external application, but therapeutic effect is not obvious, takes orally Medicine slowly effect, the affected part though liniment can go directly, aggravates patient pain, and salivation is more than, causes medicinal powder to be diluted, and increase Plus the pain of patient, it is difficult to it is widely accepted.
The content of the invention
In order to solve the above problems, the present invention discloses a kind of lozenge for treating canker sore, and the lozenge can go directly affected part, Mitigate patient suffering, rapid healing canker sore has no side effect, and can avoid canker sore recurrent exerbation.
The present invention is achieved through the following technical solutions:
A kind of lozenge for treating canker sore, is made by the component of certain mass number, the certain mass number Component includes:Alum 20-32 parts, borneol 5-8 parts, honeysuckle 15-20 parts, cape jasmine 10-15 parts, peppermint 12-18 parts, Lasiosphaera fenzlii 10- 16 parts, Momordica grosvenori 6-12 parts, aloe 10-14 parts, parasitic loranthus 14-20 part, diluent 30-45 parts, adhesive 8-12 parts.
Theory of traditional Chinese medical science thinks that canker sore is due to the wet Sheng of product the spleen-heat syndrome, fire excess from yin deficiency, immunologic hypofunction institute in internal heat Cause, the present invention using the traditional Chinese medicine ingredients such as cold borneol, honeysuckle, cape jasmine, peppermint, aloe, and disinfecting detoxifying alum, The compositions such as Momordica grosvenori, Lasiosphaera fenzlii, while oral environment, swelling and pain relieving is effectively improved, medicine absorbs with saliva into stomach Jing Afterwards, the wet Sheng of the spleen-heat syndrome, fire excess from yin deficiency situation in human body can be effectively improved, environment in conditioning prevents canker sore from root Recurrent exerbation.
Preferably, the component of the certain mass number includes:25 parts of alum, 7 parts of borneol, 18 parts of honeysuckle, cape jasmine 12 Part, 15 parts of peppermint, 14 parts of Lasiosphaera fenzlii, 8 parts of Momordica grosvenori, 12 parts of aloe, 16 parts of parasitic loranthus, 38 parts of diluent, 10 parts of adhesive.
Preferably, the component of the certain mass number includes:26 parts of alum, 6 parts of borneol, 16 parts of honeysuckle, cape jasmine 13 Part, 14 parts of peppermint, 15 parts of Lasiosphaera fenzlii, 9 parts of Momordica grosvenori, 11 parts of aloe, 18 parts of parasitic loranthus, 40 parts of diluent, 11 parts of adhesive.
When the mass fraction of each component takes above-mentioned two groups of preferred values, the effect of drug therapy canker sore of the present invention reaches Most preferably.
Further, the diluent is the mixture of one or more in fructose, lactose or maltose.Diluent is used for Improve medicine mouthfeel, it is to avoid when taking as lozenge, cause human body uncomfortable, be particularly suited for children taking.
Described adhesive is 70% polyethylene glycol.
A kind of preparation method of the lozenge for treating canker sore, it is characterised in that comprise the following steps:
(1) get the raw materials ready, weigh honeysuckle, cape jasmine, peppermint, Lasiosphaera fenzlii, Momordica grosvenori, aloe and parasitic loranthus according to quality parts ratio standby With;
(2) material got ready in step (1) is put into reactor, adds water and boil, after seething with excitement, small fire infusion 2-4 Filter after hour, take filtrate and concentrated;
(3) alum and borneol are weighed according to quality parts ratio, is ground into the powder of 260-400, by alum and borneol powder It is mixed into step (2) and is mixed in the filtrate of concentration, add diluent to be sufficiently mixed, finally adds polyglycol solution mixing, Tablet is made, drying is obtained the medicine for the treatment of canker sore.
Medicine in the present invention can also make pill buccal, or directly as endo-medicine.
The present invention compared with prior art, has the following advantages and advantages:
A kind of lozenge for treating canker sore of the present invention, using cold borneol, honeysuckle, cape jasmine, peppermint, aloe etc. Traditional Chinese medicine ingredients, and the composition such as alum, Momordica grosvenori, the Lasiosphaera fenzlii of disinfecting detoxifying, be effectively improved oral environment, swelling and pain relieving it is same When, medicine enters stomach Jing after absorbing with saliva, can be effectively improved the wet Sheng of the spleen-heat syndrome, fire excess from yin deficiency situation in human body, nurses one's health Interior environment, canker sore recurrent exerbation is prevented from root.
Specific embodiment
To make the object, technical solutions and advantages of the present invention become more apparent, with reference to embodiment, to present invention work Further to describe in detail, exemplary embodiment and its explanation of the invention is only used for explaining the present invention, is not intended as to this The restriction of invention.
Embodiment 1
A kind of lozenge for treating canker sore, is made by the component of certain mass number, the certain mass number Component includes:20 parts of alum, 5 parts of borneol, 15 parts of honeysuckle, 10 parts of cape jasmine, 12 parts of peppermint, 10 parts of Lasiosphaera fenzlii, 12 parts of Momordica grosvenori, reed 14 parts of luxuriant growth, 20 parts of parasitic loranthus, 45 parts of diluent, 12 parts of adhesive.
Further, the diluent is the mixture of one or more in fructose, lactose or maltose.
Described adhesive is 70% polyethylene glycol.
A kind of preparation method of the lozenge for treating canker sore, it is characterised in that comprise the following steps:
(1) get the raw materials ready, weigh honeysuckle, cape jasmine, peppermint, Lasiosphaera fenzlii, Momordica grosvenori, aloe and parasitic loranthus according to quality parts ratio standby With;
(2) material got ready in step (1) is put into reactor, adds water and boil, after seething with excitement, small fire infusion 4 is little When after filter, take filtrate and concentrated;
(3) alum and borneol are weighed according to quality parts ratio, is ground into 400 powder, alum and borneol powder are mixed into Mix in the filtrate of concentration in step (2), add maltose to be sufficiently mixed, finally add polyglycol solution mixing, make Tablet, drying is obtained the medicine for the treatment of canker sore.
Embodiment 2
A kind of lozenge for treating canker sore, is made by the component of certain mass number, the certain mass number Component includes:32 parts of alum, 8 parts of borneol, 20 parts of honeysuckle, 15 parts of cape jasmine, 18 parts of peppermint, 16 parts of Lasiosphaera fenzlii, 6 parts of Momordica grosvenori, reed 10 parts of luxuriant growth, 14 parts of parasitic loranthus, 30 parts of diluent, 8 parts of adhesive.
Further, the diluent is the mixture of one or more in fructose, lactose or maltose.
Described adhesive is 70% polyethylene glycol.
A kind of preparation method of the lozenge for treating canker sore, it is characterised in that comprise the following steps:
(1) get the raw materials ready, weigh honeysuckle, cape jasmine, peppermint, Lasiosphaera fenzlii, Momordica grosvenori, aloe and parasitic loranthus according to quality parts ratio standby With;
(2) material got ready in step (1) is put into reactor, adds water and boil, after seething with excitement, small fire infusion 2 is little When after filter, take filtrate and concentrated;
(3) alum and borneol are weighed according to quality parts ratio, is ground into 260 powder, alum and borneol powder are mixed into Mix in the filtrate of concentration in step (2), add lactose to be sufficiently mixed, finally add polyglycol solution mixing, make piece Agent, drying is obtained the medicine for the treatment of canker sore.
Embodiment 3
A kind of lozenge for treating canker sore, is made by the component of certain mass number, the certain mass number Component includes:25 parts of alum, 7 parts of borneol, 18 parts of honeysuckle, 12 parts of cape jasmine, 15 parts of peppermint, 14 parts of Lasiosphaera fenzlii, 8 parts of Momordica grosvenori, reed 12 parts of luxuriant growth, 16 parts of parasitic loranthus, 38 parts of diluent, 10 parts of adhesive.
Further, the diluent is the mixture of one or more in fructose, lactose or maltose.
Described adhesive is 70% polyethylene glycol.
A kind of preparation method of the lozenge for treating canker sore, it is characterised in that comprise the following steps:
(1) get the raw materials ready, weigh honeysuckle, cape jasmine, peppermint, Lasiosphaera fenzlii, Momordica grosvenori, aloe and parasitic loranthus according to quality parts ratio standby With;
(2) material got ready in step (1) is put into reactor, adds water and boil, after seething with excitement, small fire infusion 3 is little When after filter, take filtrate and concentrated;
(3) alum and borneol are weighed according to quality parts ratio, is ground into 300 powder, alum and borneol powder are mixed into Mix in the filtrate of concentration in step (2), add fructose to be sufficiently mixed, finally add polyglycol solution mixing, make piece Agent, drying is obtained the medicine for the treatment of canker sore.
Embodiment 4
A kind of lozenge for treating canker sore, is made by the component of certain mass number, the certain mass number Component includes:26 parts of alum, 6 parts of borneol, 16 parts of honeysuckle, 13 parts of cape jasmine, 14 parts of peppermint, 15 parts of Lasiosphaera fenzlii, 9 parts of Momordica grosvenori, reed 11 parts of luxuriant growth, 18 parts of parasitic loranthus, 40 parts of diluent, 11 parts of adhesive.
Further, the diluent is the mixture of one or more in fructose, lactose or maltose.
Described adhesive is 70% polyethylene glycol.
A kind of preparation method of the lozenge for treating canker sore, it is characterised in that comprise the following steps:
(1) get the raw materials ready, weigh honeysuckle, cape jasmine, peppermint, Lasiosphaera fenzlii, Momordica grosvenori, aloe and parasitic loranthus according to quality parts ratio standby With;
(2) material got ready in step (1) is put into reactor, adds water and boil, after seething with excitement, small fire infusion 4 is little When after filter, take filtrate and concentrated;
(3) alum and borneol are weighed according to quality parts ratio, is ground into 400 powder, alum and borneol powder are mixed into Mix in the filtrate of concentration in step (2), add fructose to be sufficiently mixed, finally add polyglycol solution mixing, make piece Agent, drying is obtained the medicine for the treatment of canker sore.
Embodiment 5
A kind of lozenge for treating canker sore, is made by the component of certain mass number, the certain mass number Component includes:28 parts of alum, 5 parts of borneol, 17 parts of honeysuckle, 11 parts of cape jasmine, 16 parts of peppermint, 13 parts of Lasiosphaera fenzlii, 10 parts of Momordica grosvenori, reed 13 parts of luxuriant growth, 17 parts of parasitic loranthus, 42 parts of diluent, 9 parts of adhesive.
Further, the diluent is the mixture of one or more in fructose, lactose or maltose.
Described adhesive is 70% polyethylene glycol.
A kind of preparation method of the lozenge for treating canker sore, it is characterised in that comprise the following steps:
(1) get the raw materials ready, weigh honeysuckle, cape jasmine, peppermint, Lasiosphaera fenzlii, Momordica grosvenori, aloe and parasitic loranthus according to quality parts ratio standby With;
(2) material got ready in step (1) is put into reactor, adds water and boil, after seething with excitement, small fire infusion 2 is little When after filter, take filtrate and concentrated;
(3) alum and borneol are weighed according to quality parts ratio, is ground into 400 powder, alum and borneol powder are mixed into Mix in the filtrate of concentration in step (2), add maltose to be sufficiently mixed, finally add polyglycol solution mixing, make Tablet, drying is obtained the medicine for the treatment of canker sore.
Medicine Jing patient's buccal of obtained treatment canker sore, can fast and effectively alleviate in above-described embodiment 1-5 Pain at canker sore, rapid healing cavity ulcer, and the traditional Chinese medicine ingredients in lozenge can be effectively improved patient's physique, it is to avoid mouth Chamber ulcer recurrent exerbation.
Above-described specific embodiment, has been carried out further to the purpose of the present invention, technical scheme and beneficial effect Describe in detail, should be understood that the specific embodiment that the foregoing is only the present invention, be not intended to limit the present invention Protection domain, all any modification, equivalent substitution and improvements within the spirit and principles in the present invention, done etc. all should include Within protection scope of the present invention.

Claims (6)

1. a kind of lozenge for treating canker sore, is made by the component of certain mass number, it is characterised in that certain matter The component of amount number includes:Alum 20-32 parts, borneol 5-8 parts, honeysuckle 15-20 parts, cape jasmine 10-15 parts, peppermint 12-18 parts, Lasiosphaera fenzlii 10-16 parts, Momordica grosvenori 6-12 parts, aloe 10-14 parts, parasitic loranthus 14-20 part, diluent 30-45 parts, adhesive 8-12 Part.
2. a kind of lozenge for treating canker sore according to claim 1, it is characterised in that the certain mass number Component includes:25 parts of alum, 7 parts of borneol, 18 parts of honeysuckle, 12 parts of cape jasmine, 15 parts of peppermint, 14 parts of Lasiosphaera fenzlii, 8 parts of Momordica grosvenori, reed 12 parts of luxuriant growth, 16 parts of parasitic loranthus, 38 parts of diluent, 10 parts of adhesive.
3. a kind of lozenge for treating canker sore according to claim 1, it is characterised in that the certain mass number Component includes:26 parts of alum, 6 parts of borneol, 16 parts of honeysuckle, 13 parts of cape jasmine, 14 parts of peppermint, 15 parts of Lasiosphaera fenzlii, 9 parts of Momordica grosvenori, reed 11 parts of luxuriant growth, 18 parts of parasitic loranthus, 40 parts of diluent, 11 parts of adhesive.
4. a kind of lozenge for treating canker sore according to any one of claim 1-3, it is characterised in that the dilution Agent is the mixture of one or more in fructose, lactose or maltose.
5. a kind of lozenge for treating canker sore according to claim 4, it is characterised in that described adhesive is 70% Polyethylene glycol.
6. the preparation method of a kind of lozenge for treating canker sore as any one of claim 1-6, it is characterised in that Comprise the following steps:
(1) get the raw materials ready, weigh honeysuckle, cape jasmine, peppermint, Lasiosphaera fenzlii, Momordica grosvenori, aloe and parasitic loranthus according to quality parts ratio standby;
(2) material got ready in step (1) is put into reactor, adds water and boil, after seething with excitement, small fire infusion 2-4 hours After filter, take filtrate and concentrated;
(3) alum and borneol are weighed according to quality parts ratio, is ground into the powder of 260-400, alum and borneol powder are mixed into Mix in the filtrate of concentration in step (2), add diluent to be sufficiently mixed, finally add polyglycol solution mixing, make Tablet, drying is obtained the medicine for the treatment of canker sore.
CN201710150459.3A 2017-03-14 2017-03-14 Buccal tablet for treating oral ulcer Pending CN106620081A (en)

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107456537A (en) * 2017-08-01 2017-12-12 安徽兆龙生物科技有限公司 A kind of mouth ulcer lozenge and preparation method thereof

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CN101391011A (en) * 2008-11-03 2009-03-25 朱惠芬 Pure Chinese herbal medicine gargle water for treating oral inflammation
CN102526643B (en) * 2012-03-22 2013-09-11 常熟市虞山绿茶有限公司 Chinese herbal medicine buccal tablet for treating dental ulcer

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CN1500521A (en) * 2002-06-18 2004-06-02 山东绿叶制药股份有限公司 Keep-in-mouth tablet for oral ulcer and preparation method
CN101391011A (en) * 2008-11-03 2009-03-25 朱惠芬 Pure Chinese herbal medicine gargle water for treating oral inflammation
CN102526643B (en) * 2012-03-22 2013-09-11 常熟市虞山绿茶有限公司 Chinese herbal medicine buccal tablet for treating dental ulcer

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107456537A (en) * 2017-08-01 2017-12-12 安徽兆龙生物科技有限公司 A kind of mouth ulcer lozenge and preparation method thereof

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