CN106619447A - Herbal mouthwash and preparation method thereof - Google Patents

Herbal mouthwash and preparation method thereof Download PDF

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Publication number
CN106619447A
CN106619447A CN201611133732.3A CN201611133732A CN106619447A CN 106619447 A CN106619447 A CN 106619447A CN 201611133732 A CN201611133732 A CN 201611133732A CN 106619447 A CN106619447 A CN 106619447A
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extract
water
parts
herbal
herb
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李晓光
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/97Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/96Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
    • A61K8/98Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin
    • A61K8/987Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution of animal origin of species other than mammals or birds
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q11/00Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses

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  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Birds (AREA)
  • Zoology (AREA)
  • Oral & Maxillofacial Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Microbiology (AREA)
  • Mycology (AREA)
  • Cosmetics (AREA)

Abstract

The invention relates to herbal mouthwash and a preparation method thereof. The herbal mouthwash is prepared from the following components in parts by weight: 0.01 to 0.03 part of a sweetener, 0.04 to 0.1 part of Tween 80, 0.04 to 0.1 part of sodium chloride, 0.5 to 4 parts of herbal extract and the balance of water, wherein the herbal extract comprises herba portulacae extract, rhizoma coptidis extract, radix scrophulariae extract, perilla nankinensis herb extract, spora lygodii herb extract, swertia pseudochinensis herb extract, folium turpiniae extract, nutgall extract and bur beggarticks herb extract. The herbal mouthwash provided by the invention has the effects of diminishing inflammation and swelling, small irritation to oral cavities, fresh taste and good mouth washing effect and can be used for protecting oral cavity mucosa.

Description

A kind of herbal mouthwash and preparation method thereof
Technical field
The present invention relates to oral care product technical field, especially a kind of with cleaning oral cavity, solve various focusing depths represented and swell Herbal mouthwashes of oral problem such as pain and preparation method thereof.
Background technology
Oral cavity (oral cavity) is the start-up portion of digest tube.The antetheca for having the organs such as tooth, tongue, oral cavity in oral cavity is Lip, side wall are cheek, top is palate, oral cavity bottom is the structure such as mucous membrane and flesh.Common brushes teeth, and toothpaste toothbrush is difficult cleaning to oral cavity, For example teeth space, upper oral cavity and the position such as sublingual, it is incomplete to easily cause cleaning, causes periodontitis and oral hygiene is unclean, periodontal The mouth diseases such as calculus, carious tooth, stomatitis, cheilitis, oral mucosa ulcer, glossitis, swelling, pain, it is necessary to use mouthwash Deeply nursing comprehensively.
Oral health issue is more and more concerned, and during gum swelling pain, medication is inconvenient directly to be reached, and is brushed teeth easily Increase swelling pain, and the antiphlogistic that medical toothpaste is used is often antibioticses, current abuse of antibiotics is now extremely serious, Therefore it is more convenient using mouthwash.Some are natural for alkaloids, flavonoids, protein-based, organic acid and phenolic compound etc. Composition, the characteristics of with bactericidal, to the basic fanout free region of human body, also containing multivitamin, mineral matter and biologically active because Son, improving immunocompetence resists adventitious viruses, bacterial invasion.Therefore the deficiencies in the prior art are to lack draft to gargle Water, it is to avoid use antibiotic to solve the oral problems such as cleaning is incomplete, various focusing depths represented swells and ache.
The content of the invention
In view of the shortcomings of the prior art, the invention provides a kind of herbal mouthwash and preparation method thereof, reaches both Oral cavity can be cleaned, the oral problem that various focusing depths represented swells and ache can be solved again.
To achieve these goals, the present invention is by the following technical solutions realizing:A kind of herbal mouthwash, including under Row parts by weight component:Sweetener 0.01-0.03 parts, Tween 80 0.04-0.1 parts, sodium chloride 0.04-0.1 parts, draft is extracted Thing 0.5-4 parts, remaining component be water, wherein herb extract include purslane extract, coptis extract, Radix Scrophulariae extract, Extractive of perilla, Spora Lygodii extract, knurl hair Herba Swertiae bimaculatae extract, leaf of Turpinia pomifera (Roxb) D O. extract, nutgall extractive and bur beggar-ticks Extract.
Preferably, a kind of herbal mouthwash, including following parts by weight component:0.02 part of sweetener, Tween 80 0.07 Part, 0.07 part of sodium chloride, 2 parts of herb extract, remaining component is water, and wherein herb extract includes purslane extract, Huang Coptis extract, Radix Scrophulariae extract, extractive of perilla, Spora Lygodii extract, knurl hair Herba Swertiae bimaculatae extract, leaf of Turpinia pomifera (Roxb) D O. extract, Nutgall extractive and bur beggar-ticks extract.
Preparation method is as follows:
The first step:The extraction of draft extract:Respectively by purslane, the coptis, purple perilla, Lygodium japonicum, acute turpinia leaf, plus 2-4 times of water, Ultrasound invades bubble 2-4 hour extractions, and supernatant is centrifuged to obtain afterwards, and reduced pressure concentration obtains concentrate, obtains water extract of Portulaca oleracea L, coptis water extraction Take thing, purple perilla water extract, Lygodium japonicum water extract and water extract of turpinia formosana leaves;Respectively by radix scrophulariae, knurl hair Swertia patens, powder It is broken, 2-4 times of 90% EtOH Sonicate immersion 2-4 hour extraction is added, supernatant is centrifuged to obtain afterwards, reduced pressure concentration obtains concentrate, obtains knurl hair Swertia patens ethanol extract and radix scrophulariae ethanol extract;Chinese gall, bur beggar-ticks are crushed respectively, adds 2-4 times of 40-50% ethanol Ultrasound immersion 2-4 hour extractions, are centrifuged afterwards to obtain supernatant, and reduced pressure concentration obtains concentrate, obtains Chinese gall ethanol extract and wolf handle Careless ethanol extract;
Second step, by weighing sweetener 0.01-0.03 parts, Tween 80 0.04-0.1 parts, sodium chloride 0.04-0.1 by weight Part, herb extract 0.5-4 parts, balance of water is well mixed, and obtains herbal mouthwash.
Preferably, reduced pressure concentration is obtained in concentrate step in the first step, each concentrated solution density is 1.05-1.15, i.e., respectively The density of draft extract is 1.05-1.15.
The herb extract for wherein adding has Flavonoid substances in purslane common to 6 kinds of staphylococcus aureus etc. Pathogenic bacteria have obvious killing action;Coptis heat-clearing and damp-drying drug, purging intense heat and detonicating, with the effect of broad-spectrum antiseptic antiprotozoan;Radix scrophulariae heat-clearing is cool Blood, nourishing Yin and promoting production of body fluid, purging intense heat and detonicating and profit pharynx relieves the pain, the inhibitory effect of radix scrophulariae leaf is strong, wherein particularly bright to staphylococcus aureus It is aobvious;Perillaldehyde in perilla leaf has strength killing action to Escherichia coli, shigella dysenteriae, staphylococcus etc.;Lygodium japonicum can be clear Thermal detoxification, inducing diuresis for removing edema has antibacterial activity, obvious to staphylococcus aureus fungistatic effect;Knurl hair Swertia patens are clearing heat and detoxicating, entirely Grass contains alkaloid, flavone compound, wherein as medicine flavones (swertisin SwertiSin), with antibacterial action, swertiamarin is easy From skin absorption, Jing enzyme hydrolysis, and Jing molecular rearrangements and generate glucoside unit erythrocentaurin (Erythrocentaurin), can expand Capillary is opened, the enzyme system of skin histology is enduringly activated and is improved its biochemical function;Acute turpinia leaf is clearing heat and detoxicating, and profit pharynx disappears Swollen, promoting blood circulation and stopping pain, acute turpinia leaf water drug-decocting concentrating liquid has stronger bacteriostasis to staphylococcus aureus, with every 1ml1u moulds Element is equivalent;Chinese gall has astriction rich in tannic acid, can make the local such as skin, mucous membrane, ulcer tissue protein solidify and Astriction is played, blood clotting can be accelerated and had anastalsis, and to staphylococcus aureus, bacterium flexneri, hog cholera Bacillus and Escherichia coli have inhibitory action;Bur beggar-ticks can clearing heat and detoxicating, swelling and pain relieving.All kinds of herb extracts complement each other, Elimination oral bacteria can be played, the effect in oral cavity is cleaned, all kinds of draft extracts may also function as the effect of anti-inflammatory analgetic.
Obviously, in the present invention as needed, other raw materials, such as preservative, essence can also be added, other raw materials add To enter realize substantially its respective function, generally do not interfere with the key property of the present invention.Those skilled in the art need not pay wound The property made is implemented by working.
Beneficial effects of the present invention:Compared with existing mouthwash, the herbal mouthwash of the present invention, draft extract has Bactericidal effect, gargles better, keeps oral cleaning, while there is clearing heat and detoxicating, anti-inflammatory analgetic and other effects, to oral cavity Stimulate little, taste is pure and fresh.The preparation method more effectively extracts herb extract, makes better.
Specific embodiment
With reference to specific embodiment, the present invention is further elucidated, it should be understood that following specific embodiments are only used for The bright present invention rather than restriction the scope of the present invention.
A kind of herbal mouthwash of embodiment 1, including parts by weight composition:0.01 part of sweetener, 0.04 part of Tween 80, chlorine Change 0.04 part of sodium, 0.5 part of herb extract, remaining component is water, and wherein herb extract includes that purslane extract, the coptis are carried Take thing, Radix Scrophulariae extract, extractive of perilla, Spora Lygodii extract, knurl hair Herba Swertiae bimaculatae extract, leaf of Turpinia pomifera (Roxb) D O. extract, five times Seed extract and bur beggar-ticks extract.
Preparation method:
The first step:The extraction of draft extract:Respectively by purslane, the coptis, purple perilla, Lygodium japonicum, acute turpinia leaf, plus 2 times of water, surpass Sound is invaded bubble and is extracted for 2 hours, and supernatant is centrifuged to obtain afterwards, and reduced pressure concentration obtains concentrate, and concentrated solution density is 1.01, obtains purslane water extraction Take thing, coptis root aqueous extract, purple perilla water extract, Lygodium japonicum water extract and water extract of turpinia formosana leaves;Respectively by radix scrophulariae, knurl Hair Swertia patens, crush, and add 2 times of 90% EtOH Sonicate to soak 2 hours and extract, and supernatant is centrifuged to obtain afterwards, and reduced pressure concentration must be concentrated Liquid, concentrated solution density is 1.05, obtains knurl hair Swertia patens ethanol extract and radix scrophulariae ethanol extract;Respectively by Chinese gall, wolf handle Grass meal is broken, adds 2 times of 40% EtOH Sonicate to soak 2 hours and extracts, and supernatant is centrifuged to obtain afterwards, and reduced pressure concentration obtains concentrate, concentrate Density is 1.05, obtains Chinese gall ethanol extract and bur beggar-ticks ethanol extract;Each draft extract mixed in equal amounts.
Second step, by 0.01 part of sweetener, 0.04 part of Tween 80,0.04 part of sodium chloride is weighed by weight, draft is carried 0.5 part of thing is taken, balance of water is well mixed, and obtains herbal mouthwash.
A kind of herbal mouthwash of embodiment 2, including parts by weight composition:0.03 part of sweetener, 0.1 part of Tween 80, chlorination 0.1 part of sodium, 4 parts of herb extract, remaining component be water, wherein herb extract include purslane extract, coptis extract, Radix Scrophulariae extract, extractive of perilla, Spora Lygodii extract, knurl hair Herba Swertiae bimaculatae extract, leaf of Turpinia pomifera (Roxb) D O. extract, Chinese gall are extracted Thing and bur beggar-ticks extract.
Preparation method
The first step:The extraction of draft extract:Respectively by purslane, the coptis, purple perilla, Lygodium japonicum, acute turpinia leaf, plus 4 times of water, surpass Sound is invaded bubble and is extracted for 4 hours, and supernatant is centrifuged to obtain afterwards, and reduced pressure concentration obtains concentrate, is obtained water extract of Portulaca oleracea L, coptis water and is extracted Thing, purple perilla water extract, Lygodium japonicum water extract and water extract of turpinia formosana leaves;Respectively by radix scrophulariae, knurl hair Swertia patens, crush, Add 4 times of 90% EtOH Sonicate to soak 4 hours to extract, supernatant is centrifuged to obtain afterwards, reduced pressure concentration obtains concentrate, obtains knurl hair Swertia patens Ethanol extract and radix scrophulariae ethanol extract;Chinese gall, bur beggar-ticks are crushed respectively, adds 4 times of 50% EtOH Sonicate immersion 4 little When extract, supernatant is centrifuged to obtain afterwards, reduced pressure concentration obtains concentrate, obtains Chinese gall ethanol extract and bur beggar-ticks ethanol extract; Each concentrated solution density is 1.15, and wherein Purslane extract accounts for the 20% of total draft extract, remaining extract equivalent.
Second step, by 0.03 part of sweetener, 0.1 part of Tween 80,0.1 part of sodium chloride is weighed by weight, draft is extracted 4 parts of thing, balance of water is well mixed, and obtains herbal mouthwash.
A kind of herbal mouthwash of embodiment 3, each component is constituted by mass percentage:0.02 part of sweetener, Tween 80 0.07 Part, 0.07 part of sodium chloride, 2 parts of herb extract, remaining component is water, and wherein herb extract includes purslane extract, Huang Coptis extract, Radix Scrophulariae extract, extractive of perilla, Spora Lygodii extract, knurl hair Herba Swertiae bimaculatae extract, leaf of Turpinia pomifera (Roxb) D O. extract, Nutgall extractive and bur beggar-ticks extract.
Preparation method
The first step:The extraction of draft extract:Respectively by purslane, the coptis, purple perilla, Lygodium japonicum, acute turpinia leaf, plus 3 times of water, surpass Sound is invaded bubble and is extracted for 3 hours, and supernatant is centrifuged to obtain afterwards, and reduced pressure concentration obtains concentrate, is obtained water extract of Portulaca oleracea L, coptis water and is extracted Thing, purple perilla water extract, Lygodium japonicum water extract and water extract of turpinia formosana leaves;Respectively by radix scrophulariae, knurl hair Swertia patens, crush, Add 3 times of 90% EtOH Sonicate to soak 3 hours to extract, supernatant is centrifuged to obtain afterwards, reduced pressure concentration obtains concentrate, obtains knurl hair Swertia patens Ethanol extract and radix scrophulariae ethanol extract;Chinese gall, bur beggar-ticks are crushed respectively, adds 3 times of 50% EtOH Sonicate immersion 3 little When extract, supernatant is centrifuged to obtain afterwards, reduced pressure concentration obtains concentrate, obtains Chinese gall ethanol extract and bur beggar-ticks ethanol extract; Each concentrated solution density is 1.15, each draft extract equal proportion mixing.
Second step, by 0.02 part of sweetener, 0.07 part of Tween 80,0.07 part of sodium chloride is weighed by weight, draft is carried 2 parts of thing is taken, balance of water is well mixed, and obtains herbal mouthwash.
Technological means disclosed in the present invention program is not limited only to the technological means disclosed in above-mentioned embodiment, also includes Constituted technical scheme is combined by above technical characteristic.It should be pointed out that for those skilled in the art For, under the premise without departing from the principles of the invention, some improvements and modifications can also be made, these improvements and modifications are also considered as Protection scope of the present invention.

Claims (5)

1. a kind of herbal mouthwash, it is characterised in that including following parts by weight component:Sweetener 0.01-0.03 parts, Tween 80 0.04-0.1 parts, sodium chloride 0.04-0.1 parts, herb extract 0.5-4 parts, remaining component is water, and wherein herb extract includes Purslane extract, coptis extract, Radix Scrophulariae extract, extractive of perilla, Spora Lygodii extract, knurl hair Herba Swertiae bimaculatae extract, Leaf of Turpinia pomifera (Roxb) D O. extract, nutgall extractive and bur beggar-ticks extract.
2. a kind of herbal mouthwash as claimed in claim 1, it is characterised in that including following parts by weight component:Sweetener 0.02 part, 0.07 part of Tween 80,0.07 part of sodium chloride, 2 parts of herb extract, remaining component is water, wherein herb extract bag Include purslane extract, coptis extract, Radix Scrophulariae extract, extractive of perilla, Spora Lygodii extract, knurl hair Swertia patens to extract Thing, leaf of Turpinia pomifera (Roxb) D O. extract, nutgall extractive and bur beggar-ticks extract.
3. a kind of herbal mouthwash as claimed in claim 1 or 2, it is characterised in that the sweetener is xylitol.
4. a kind of preparation method of herbal mouthwash as claimed in claim 1, it is characterised in that step is as follows:
The first step:The extraction of draft extract:Respectively by purslane, the coptis, purple perilla, Lygodium japonicum, acute turpinia leaf, plus 2-4 times of water, Ultrasound invades bubble 2-4 hour extractions, and supernatant is centrifuged to obtain afterwards, and reduced pressure concentration obtains concentrate, obtains water extract of Portulaca oleracea L, coptis water extraction Take thing, purple perilla water extract, Lygodium japonicum water extract and water extract of turpinia formosana leaves;Respectively by radix scrophulariae, knurl hair Swertia patens, powder It is broken, 2-4 times of 90% EtOH Sonicate immersion 2-4 hour extraction is added, supernatant is centrifuged to obtain afterwards, reduced pressure concentration obtains concentrate, obtains knurl hair Swertia patens ethanol extract and radix scrophulariae ethanol extract;Chinese gall, bur beggar-ticks are crushed respectively, adds 2-4 times of 40-50% ethanol Ultrasound immersion 2-4 hour extractions, are centrifuged afterwards to obtain supernatant, and reduced pressure concentration obtains concentrate, obtains Chinese gall ethanol extract and wolf handle Careless ethanol extract;
Second step, by weighing sweetener 0.01-0.03 parts, Tween 80 0.04-0.1 parts, sodium chloride 0.04-0.1 by weight Part, herb extract 0.5-4 parts, balance of water is well mixed, and obtains herbal mouthwash.
5. a kind of preparation method of herbal mouthwash as claimed in claim 4, reduced pressure concentration obtains concentrate in the first step In step, each concentrated solution density is 1.05-1.15.
CN201611133732.3A 2016-12-10 2016-12-10 Herbal mouthwash and preparation method thereof Withdrawn CN106619447A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107320401A (en) * 2017-08-18 2017-11-07 武汉华士特工业生物技术开发有限公司 A kind of mouthwash of pre- anti-caries and preparation method thereof
CN108721176A (en) * 2018-08-31 2018-11-02 黄冈师范学院 A kind of mouthwash and preparation method thereof

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107320401A (en) * 2017-08-18 2017-11-07 武汉华士特工业生物技术开发有限公司 A kind of mouthwash of pre- anti-caries and preparation method thereof
CN108721176A (en) * 2018-08-31 2018-11-02 黄冈师范学院 A kind of mouthwash and preparation method thereof

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Application publication date: 20170510