CN106615815A - Anti-stress preparation for pigs and preparation method thereof - Google Patents

Anti-stress preparation for pigs and preparation method thereof Download PDF

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Publication number
CN106615815A
CN106615815A CN201611250824.XA CN201611250824A CN106615815A CN 106615815 A CN106615815 A CN 106615815A CN 201611250824 A CN201611250824 A CN 201611250824A CN 106615815 A CN106615815 A CN 106615815A
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parts
preparation
stress
medicinal powder
pigs
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任守国
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SICHUAN WANGDA FEED CO Ltd
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SICHUAN WANGDA FEED CO Ltd
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    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02PCLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P60/00Technologies relating to agriculture, livestock or agroalimentary industries
    • Y02P60/80Food processing, e.g. use of renewable energies or variable speed drives in handling, conveying or stacking
    • Y02P60/87Re-use of by-products of food processing for fodder production

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  • Fodder In General (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention discloses an anti-stress preparation for pigs and a preparation method thereof. The anti-stress preparation comprises, by weight parts, 6-8 parts of costusroot, 6-8 parts of fructus aurantii immaturus, 3-4 parts of curcuma aerugionosa, 6-8 parts of tangerine peel, 4-7 parts of rhubarb, 3-6 parts of astragalus, 1-3 parts of scutellaria baicalensis, 6-10 parts of honeysuckle, 7-12 parts of hawthorn, 10-14 parts of raw malt, 3-6 parts of codonopsis pilosula, 1-5 parts of glucose oxidase, 5-7 parts of mannase, 0.8-1.0 part of 5-amino-levulinic acid and 3-4 parts of taurine. According to the anti-stress preparation for pigs and the preparation method thereof, the formula is comprehensively considered from aspects such as immunity boost, anti-stress, qi circulation and spleen strengthening, digestion promotion, stomach invigorating, reduction of intestinal inflammation reaction and oxidative stress, shortcoming in conventional technologies are overcome, anti-stress action is strengthened while growth is promoted, health conditions of pigs are enhanced obviously, and the death rate is greatly reduced.

Description

A kind of live pig resisting stress preparation and preparation method thereof
Technical field
The present invention relates to a kind of feed addictive and preparation method thereof, more specifically the present invention relates to a kind of live pig is anti-should Sharp preparation and preparation method thereof, belongs to feed additive field.
Background technology
Porcine stress syndrome is big problem very important in modern mechanical, intensive pig production and veterinary practice, provisions Pig industry brings huge loss, is increasingly paid much attention to by boundary of raising pigs, and how to prevent and treat pig in time stress Syndrome is also into one of important research topic.
Stress reaction initial stage, affected pig muscle and tail tremble, expiratory dyspnea, and skin is red a burst of white a burst of, and body temperature rises rapidly Height, mucous membrane cyanosis.Later stage, muscle is significantly stiff, dysstasia, exophthalmos, hyperpyrexia, in shock state.Stress reaction is most tight Weight, any symptom is can not see with regard to die by visitation of God, i.e., so-called " prominent pattern synthesis of getting killed are levied ".
Cause live pig stress factor it is a lot, including feeding and management factor (as imprisonment, dense rearing, seizure, turn group and transport, Fight, malnutrition, immunity inoculation, castration, earmarking, docking etc.), environmental factor is (such as heat, severe cold, intense radiation, low gas Pressure, toxic and harmful, dust, moisture, high wind and harmful wind, noise etc.), microorganism infection factor is (such as bacterium, virus, parasitism Worm, mycoplasma and Chlamydia etc.), other human factors (such as the intensity of production performance is utilized, to machinery and equipment discomfort), Inherent cause (such as recessive halothane homozygote pig).It is easy to irritability syndrome in the case of factors above is present.
Stress reaction is the synthesis result of stressor and body reaction, wherein often the internal factor of body accounts for leading work With.So, adjust body internal factor stress preventing and treating in play very important effect.In the past, in production and practice External cause not enough, is only focused on merely in attention to body internal factor, and prevention effect is not very good.Stress in preventing and treating and control During the harm for bringing, by a kind of simple prevention and controls optimal prevention effect is not had.Have now been found that, using the toxicity of Chinese medicine Low, modulability is strong, sphere of action is wide etc., and a series of features are prevented and treated stress reaction.Some amino acid derivativges, specific acid Preparation etc. is due to the excitatoty effect with sympathoadrenal nerve of calming the nerves, reduce, it may have certain anti-stress effect.It is dynamic Thing when having indigestion, enteron aisle digestive function go down, because food digestion does not freely cause the intestinal tract of animal extremely uncomfortable, What is shown first is also stress reaction, so having indigestion can to a certain extent be solved, the enzyme preparation that digestive function goes down also has Have it is certain stress relief capabilities.
China national Department of Intellectual Property discloses the Chinese medicine composition of a boar resisting stress and its preparation on March 17th, 2010 Method (notification number:CN101670009A), the composition of the Chinese medicine composition of the disclosure of the invention is mainly:It is folium isatidis, Divine Comedy, old Skin, the Radix Astragali, dandelion, rheum officinale, the compound of glauber-salt and liquorice, through the finished product of both obtain crushed, sieve, mix, the Chinese medicine composition of the invention is only capable of The logical intestines of clearing heat and detoxicating, stomach invigorating, adjustment stomach are played, strengthens the effect of transporting, and preparation method is fairly simple, it is impossible in performance The optimal efficacy of medicine.
Chinese medicine resisting stress preparation in currently available technology belongs to simple primary processing, is mainly reflected in three below side Face:(1) substantially only it is made up of some conventional feeds and Chinese medicine from from formula;(2) letter has only been carried out from processing technology Single mixing, pulverization process, can not play completely the drug effect of Chinese medicine;(3) simply serve from effect ventilation invigorating the spleen, help digestion it is strong The effect of stomach, stasis removing.
The content of the invention
Present invention seek to address that the chitling road in background technology stress, transport stress, environmental stress bring disease opposing The problems such as power declines, growth gets poor results, there is provided one kind is made up of Chinese herbal medicine, specific acid supplement, amino acid derivativges and enzyme preparation , with the live pig resisting stress preparation and preparation method thereof for reducing live pig stress reaction, improving live pig premunition.
In order to realize foregoing invention purpose, its concrete technical scheme is as follows:
A kind of live pig resisting stress preparation, including the composition composition of following parts by weight:
A kind of preparation method of above-mentioned live pig resisting stress preparation, comprises the following steps:
The banksia rose, the dried immature fruit of citron orange, Wen Shu, dried orange peel, rheum officinale, the Radix Astragali, the root of large-flowered skullcap, honeysuckle, hawthorn, Fructus Hordei Germinatus and Radix Codonopsis are matched somebody with somebody as above-mentioned Square ratio is well mixed, and is then carried out after coarse crushing with the hammer crusher of hole diameter of sieve (perforated) plate 2.0mm, then is carried out with airslide disintegrating mill Prepare, in air pressure 4.2-5.5kg/cm2, rate of feeding 100-125kg/hr, make under conditions of grader electric machine frequency 15-20Hz The standby micron order Traditional Chinese drug mixture into particle diameter 30um;
Then with the ratio of 1 part of Traditional Chinese drug mixture, 3 parts of distilled water, the medicinal powder for crushing is soaked into 45-50 in distilled water Minute;
Soaked liquid medicine mixture is put into together in the reactor of 304 stainless steels and is heated to 75-80 DEG C, insulation 30-35 minutes;
Medicinal powder liquid is taken out, is further ground with colloid mill, until drug particles particle size reduction is to within 10 microns;
Glucose oxidase, mannonase taurine and 5- amino-levulic acid are pressed after medicinal powder liquid is sufficiently cool It is added in medicinal powder liquid according to above-mentioned formula rate, stirs 15 minutes, speed of agitator is 10-15 rev/min;
Plus distilled water adjustment dry matter content 15-18%, carry out low temperature spray drying and make finished product;Being dried vapo(u)rizing temperature is 170 DEG C of inlet temperature, 65 DEG C of outlet temperature, second drying time 8-15;
Use baling press packed products.
The Advantageous Effects that the present invention brings are:
(1) live pig resisting stress preparation of the invention and preparation method thereof, increases the Radix Astragali in formula, and there is the Radix Astragali tonifying Qi to consolidate Table, myogenic, enhancing body's immunity, liver protection, diuresis, the effect of resisting stress;Saponin in Radix Codonopsis can effectively strengthen maincenter Nerve, reach it is with all worries set aside with fixed attention, effectively reducing that pig is various stress disease;Haemocyanin synthesis, bone marrow protein synthesis, organ can be promoted Albumen synthesis etc., improves immunity of organisms.Meanwhile, adding glucose oxidase in formula can effectively remove freedom in enteron aisle Base, alleviates the oxidative stress phenomenon that feed brings;The beans source property enteron aisle that addition mannase can be brought with moderate reduction feed Inflammatory reaction;The metabolic process of the adjustable ferroheme of addition 5- amino-levulic acid, strengthens the oxygen carrying capability of red blood cell, is lifted The premunition of animal;Taurine can promote nutrient metabolism, protection animal body cell, the synthesis of regulation and control hormonal substance.
(2) change traditional mode completely in processing technology of the invention, according to herbal pharmacology characteristic it is original propose one Set processing technology, can effectively extract Effective Component of Chinese Medicine strengthens the absorption of stomach, so that pharmacological action is significantly strengthened.
(3) formula of the invention is from strengthen immunity, resisting stress, ventilation invigorating the spleen, food digesting stomach fortifying, reduction intestinal inflammation Consider with the aspect such as oxidative stress, the deficiency in perfect routine techniques, it is somatotrophic while enhance anti-stress effect, Pig health status is remarkably reinforced, the death rate is substantially reduced.
Specific embodiment
To make the object, technical solutions and advantages of the present invention clearer, embodiments of the present invention will be made below into One step ground is described in detail.
Embodiment one
A kind of live pig resisting stress preparation, including the composition composition of following parts by weight:6 parts of the banksia rose;6 parts of the dried immature fruit of citron orange;Literary art 3 Part;6 parts of dried orange peel;4 parts of rheum officinale;3 parts of the Radix Astragali;1 part of the root of large-flowered skullcap;6 parts of honeysuckle;7 parts of hawthorn;10 parts of Fructus Hordei Germinatus;3 parts of Radix Codonopsis;Grape 1 part of carbohydrate oxidase;5 parts of mannase;3 parts of 5- amino -0.8 part of levulic acid and taurine.
(1) first by various raw materials in above-mentioned formula (glucose oxidase, mannonase 5- amino-levulic acid and ox Except sulfonic acid) it is well mixed by above-mentioned formula rate.Then (hole diameter of sieve (perforated) plate 2.0mm) after coarse crushing is carried out with hammer crusher, It is prepared with airslide disintegrating mill again, in air pressure 4.2-5.5kg/cm2, rate of feeding 100-125kg/hr, grader motor frequency The micron order Traditional Chinese drug mixture of particle diameter 30um or so is prepared under conditions of rate 15-20Hz.
(2) and then with the ratio of 1 part of Traditional Chinese drug mixture, 3 parts of distilled water (as distilled water, it is ensured that wherein not metal ion), The medicinal powder for crushing is soaked 45-50 minutes in distilled water.
(3) soaked liquid medicine mixture is put into together in the reactor of 304 stainless steels and is heated to 75-80 DEG C, protects Warm 30-35 minutes.
(4) take out medicinal powder liquid, further ground with colloid mill, until drug particles particle size reduction to 10 microns with It is interior.
(5) by glucose oxidase, mannonase taurine, 5- amino-levulinic after medicinal powder liquid is sufficiently cool Acid is added in medicinal powder slurries according to above-mentioned formula rate, is stirred 15 minutes, and speed of agitator is 10-15 rev/min.
(6) add distilled water adjustment dry matter content 15-18%, carry out low temperature spray drying and make finished product;It is dried spraying temperature Spend for 170 DEG C of inlet temperature, 65 DEG C of outlet temperature, second drying time 8-15.
(7) it is packaged into finished product with baling press.
Embodiment two
A kind of live pig resisting stress preparation, including the composition composition of following parts by weight:8 parts of the banksia rose;8 parts of the dried immature fruit of citron orange;Literary art 4 Part;8 parts of dried orange peel;7 parts of rheum officinale;6 parts of the Radix Astragali;3 parts of the root of large-flowered skullcap;10 parts of honeysuckle;12 parts of hawthorn;14 parts of Fructus Hordei Germinatus;6 parts of Radix Codonopsis;Portugal 5 parts of grape carbohydrate oxidase;7 parts of mannase;4 parts of 5- amino -1.0 parts of levulic acid and taurine.
(1) first by various raw materials in above-mentioned formula (glucose oxidase, mannonase 5- amino-levulic acid and ox Except sulfonic acid) it is well mixed by above-mentioned formula rate.Then (hole diameter of sieve (perforated) plate 2.0mm) after coarse crushing is carried out with hammer crusher, It is prepared with airslide disintegrating mill again, in air pressure 4.2-5.5kg/cm2, rate of feeding 100-125kg/hr, grader motor frequency The micron order Traditional Chinese drug mixture of particle diameter 30um or so is prepared under conditions of rate 15-20Hz.
(2) and then with the ratio of 1 part of Traditional Chinese drug mixture, 3 parts of distilled water (as distilled water, it is ensured that wherein not metal ion), The medicinal powder for crushing is soaked 45-50 minutes in distilled water.
(3) soaked liquid medicine mixture is put into together in the reactor of 304 stainless steels and is heated to 75-80 DEG C, protects Warm 30-35 minutes.
(4) take out medicinal powder liquid, further ground with colloid mill, until drug particles particle size reduction to 10 microns with It is interior.
(5) by glucose oxidase, mannonase taurine, 5- amino-levulinic after medicinal powder liquid is sufficiently cool Acid is added in medicinal powder slurries according to above-mentioned formula rate, is stirred 15 minutes, and speed of agitator is 10-15 rev/min.
(6) add distilled water adjustment dry matter content 15-18%, carry out low temperature spray drying and make finished product;It is dried spraying temperature Spend for 170 DEG C of inlet temperature, 65 DEG C of outlet temperature, second drying time 8-15.
(7) it is packaged into finished product with baling press.
Embodiment three
Piglet is transported for long-distance and feeding experiment
The DLY weanling pigs 120 of 22 ± 1 age in days 6.35 ± 0.5kg of body weight are chosen, male and female half and half is close according to body weight Principle, is grouped at random;Test sets 2 process, and each processes 60 piglets, is processed before transporting for long-distance from purchase. Process one and do not add resisting stress preparation, the 0.1% addition pig resisting stress preparation in feed of process two in feed.Before long-distance transport Feeding, processes one and processes two equal drinking public water supplies in transportation, transport starts feeding after 12 hours, and records after transport the Feed intake, two process feeding identical daily ration during whole test, weigh on an empty stomach during 70 age in days, period record piglet Diarrhoea and death condition.
Test carries out according to a conventional method feeding and management, and periodically sterilization counts feed consumption rate to guarantee rearing conditions, calculates average Daily gain, feed intake, feed-weight ratio, observation diarrhea rate etc..Data analysis is carried out using SPSS softwares, as a result with average ± standard Difference expression, the results are shown in Table 1.
The piglet of table 1 is transported for long-distance and feeding experiment
Index Control group Test group
Initial weight kg 6.36±0.08 6.35±0.04
70 ages in days weight kg 24.77±1.02 27.92±0.86
Feed intake g 583±12.2 634±16.4
Daily gain g 376±7.1 440±6.8
Feedstuff-meat ratio 1.55±0.11 1.44±0.13
First time feed intake g after transport 150±6.2 204±9.7
Death rate % 6 0
Diarrhea rate % 26.7 13.3
Note:Diarrhea rate refers to the diarrhoea situation of 7d after wean
Adding resisting stress preparation in feed as seen from the above table can improve primary feed intake, feed intake, day after transport Weightening, feedstuff-meat ratio;Compared with control group, after transport primary feed intake, feed intake, daily gain increase by 36% respectively, 8.75%th, 17.16%, feedstuff-meat ratio reduces by 7.18%.In addition addition Antistress agent can reduce the death rate and diarrhea rate.This test As a result, it was confirmed that the pig resisting stress pharmaceutical formulation can effectively alleviate piglet stress, prevent and treat because of the irritability disease caused by stress factor Sick (common diarrhoea, oedema and cad pig syndrome), to fatten swine rearing good basis is laid.
Live pig resisting stress preparation and preparation method thereof of the present invention, increases the Radix Astragali in formula, the Radix Astragali have invigorating qi for strengthening superficies, Myogenic, enhancing body's immunity, liver protection, diuresis, the effect of resisting stress;Saponin in Radix Codonopsis can effectively strengthen maincenter god Jing, reach it is with all worries set aside with fixed attention, effectively reducing that pig is various stress disease;Haemocyanin synthesis, bone marrow protein synthesis, organ egg can be promoted White synthesis etc., improves immunity of organisms.Meanwhile, adding glucose oxidase in formula can effectively remove freedom in enteron aisle Base, alleviates the oxidative stress phenomenon that feed brings;The beans source property enteron aisle that addition mannase can be brought with moderate reduction feed Inflammatory reaction;The metabolic process of the adjustable ferroheme of addition 5- amino-levulic acid, strengthens the oxygen carrying capability of red blood cell, is lifted The premunition of animal;Taurine can promote nutrient metabolism, protection animal body cell, the synthesis of regulation and control hormonal substance.
The present invention processing technology on change traditional mode completely, according to herbal pharmacology characteristic it is original propose it is a set of plus Work technique, can effectively extract Effective Component of Chinese Medicine strengthens the absorption of stomach, so that pharmacological action is significantly strengthened.
The present invention formula from strengthen immunity, resisting stress, ventilation invigorating the spleen, food digesting stomach fortifying, reduce intestinal inflammation with The aspects such as oxidative stress consider, the deficiency in perfect routine techniques, somatotrophic while enhance anti-stress effect, bright It is aobvious to strengthen pig health status, substantially reduce the death rate.

Claims (3)

1. a kind of live pig resisting stress preparation, it is characterised in that be composed of the following parts by weight parts:
2. a kind of preparation method of live pig resisting stress preparation, it is characterised in that comprise the following steps:
The banksia rose, the dried immature fruit of citron orange, Wen Shu, dried orange peel, rheum officinale, the Radix Astragali, the root of large-flowered skullcap, honeysuckle, hawthorn, Fructus Hordei Germinatus and Radix Codonopsis are well mixed, so Carried out after coarse crushing with the hammer crusher of hole diameter of sieve (perforated) plate 2.0mm afterwards, then be prepared with airslide disintegrating mill, in air pressure 4.2- 5.5kg/cm2, rate of feeding 100-125kg/hr, be prepared into particle diameter 30um's under conditions of grader electric machine frequency 15-20Hz Micron order Traditional Chinese drug mixture;
Then with the ratio of 1 part of Traditional Chinese drug mixture, 3 parts of distilled water, the medicinal powder for crushing is soaked 45-50 minutes in distilled water;
Soaked liquid medicine mixture is put into together in the reactor of 304 stainless steels and is heated to 75-80 DEG C, is incubated 30-35 Minute;
Medicinal powder liquid is taken out, is further ground with colloid mill, until drug particles particle size reduction is to within 10 microns;
After medicinal powder liquid is sufficiently cool by glucose oxidase, mannonase taurine and 5- amino-levulic acid according to than Example is added in medicinal powder liquid, is stirred 15 minutes, and speed of agitator is 10-15 rev/min;
Plus distilled water adjustment dry matter content 15-18%, carry out low temperature spray drying and make finished product;Vapo(u)rizing temperature is dried for import 170 DEG C of temperature, 65 DEG C of outlet temperature, second drying time 8-15.
3. the preparation method of live pig resisting stress preparation as claimed in claim 2, it is characterised in that each composition is in terms of parts by weight For:
CN201611250824.XA 2016-12-30 2016-12-30 Anti-stress preparation for pigs and preparation method thereof Pending CN106615815A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108185170A (en) * 2018-03-06 2018-06-22 张掖市科瑞生态饲料研发中心 A kind of sheep anti-stress feed addictive and preparation method thereof

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Publication number Priority date Publication date Assignee Title
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CN102823778A (en) * 2012-09-24 2012-12-19 吴江市田宇生物科技有限公司 Functional feed additive special for experimental miniature pig
CN102870971A (en) * 2012-10-19 2013-01-16 四川省旺达饲料有限公司 Pig anti-stress preparation

Patent Citations (3)

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CN101822319B (en) * 2010-05-19 2012-11-07 成都巨星猪业有限公司 Pig growth promoting powder and preparation method thereof
CN102823778A (en) * 2012-09-24 2012-12-19 吴江市田宇生物科技有限公司 Functional feed additive special for experimental miniature pig
CN102870971A (en) * 2012-10-19 2013-01-16 四川省旺达饲料有限公司 Pig anti-stress preparation

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李琴等: ""氨基乙酰丙酸的生理作用及其在猪饲料中的作用",李琴等,《饲料广角》,2010年第15期,第23-25页", 《饲料广角》 *

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* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN108185170A (en) * 2018-03-06 2018-06-22 张掖市科瑞生态饲料研发中心 A kind of sheep anti-stress feed addictive and preparation method thereof

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Application publication date: 20170510