CN106615680A - Anti-stress feed additive - Google Patents
Anti-stress feed additive Download PDFInfo
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- CN106615680A CN106615680A CN201510737944.1A CN201510737944A CN106615680A CN 106615680 A CN106615680 A CN 106615680A CN 201510737944 A CN201510737944 A CN 201510737944A CN 106615680 A CN106615680 A CN 106615680A
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- feed addictive
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Abstract
The invention discloses an anti-stress feed additive. From the three aspects of supplementing lacking nutrients of an organism in a stress state, improving the immunity and oxidation resistance of an animal organism and enhancing the animal appetite, the anti-stress feed additive can make animals rapidly recover from the stress state, and can supplement essential nutrients for the animals at the same time. By adopting the anti-stress feed additive, the feed intake is increased, the production loss is produced, and the production performance is improved.
Description
Technical field
Present invention relates particularly to a kind of feed addictive of resisting stress and preparation method thereof, belongs to field of feed additive technology.
Background technology
Animal stress be referred to external world or inside it is various stimulate very much produced by nonspecific response reaction summations.20
The thirties in century, Canadian virologist Hans doctors selye delivered first on Nature with regard to stress phenomenon article,
He points out stress be just as sick, and temperature, feed ingredient, the change of feeding regime, nerve stimulation and pernicious gas etc. are permitted
More diverse virulence factor, there is same or analogous non-specific responding in body idiosyncrasy.
The effect of stressor is many, affects the various functions of body, therefore, stress be the formidable enemy of poultry industry production,
Its harm to livestock and poultry mainly has：Immunity degradation, production performance is reduced, sexual performance disorder and die by visitation of God etc., often can be given
Poultry industry brings huge loss.
In order to ensure highly efficient and productive, high-quality Animal husbandry production, the loss that stress be caused is reduced or avoids, it is real in production
In border, in addition to improving feeding and management, seed selection stress-resistant line, main is exactly to use resisting stress additive, this
Sample can be overcome or alleviated by a certain extent in response to the sharp loss for causing, and obtain higher economic benefit.
Resisting stress additive refer to alleviate, prevent and treat by stressor cause stress syndrome feed addictive.At present,
In Production of Livestock and Poultry commonly use resisting stress additive include vitamins, mineral matter, carbohydrate, organic acid, plant extracts,
Trace element or antibiotic etc..Chromium is a kind of more trace mineral supplement of Recent study.In a very long time, people
To be mistakenly considered chromium be noxious material.Until nineteen fifty-nine, Schwarz etc. are experimentally verified that Cr3+It is glucose tolerance factor (GTF)
Important activity composition, play the role of important to adjusting three major nutrient metabolism, people just gradually think that chromium is any animal
Indispensable trace element.Numerous studies show, add in Broiler Dietary chromium be improved growth performance, improve carcass quality,
Enhance immunity etc. is acted on.Luo Xu has just waited (1999) report, and 2.0mg/kg chromium is added in 0～3 week old Broiler Dietary can be obtained most
The big speed of growth, feed efficiency and maximum serum antibody titer of ND, can significantly improve alkaline phosphatase activities,
And with the increase of chromium pitch-based sphere, serum uric acid concentration is gradually lowered.
Numerous studies show that the using effect of single Antistress agent is not so good as anti-stress complex.Therefore by compound resisting stress system
It is following holistic approach direction that agent is applied on the anti-stress health-care of livestock and poultry.
The content of the invention
Present invention aim at provide one kind can effective anti-stress feed addictive, the additive is with vitamins, amino acid
Class and Organic Chromium are nucleus.
A kind of feed addictive of resisting stress that the present invention is provided includes that component includes Astragalus Root P.E, haw thorn extract, relies ammonia
Acid, methionine, tryptophan, threonine, GABA, sodium acid carbonate, potassium chloride, vitamin C, vitamin E,
Sodium selenite, Organic Chromium and pharmaceutically acceptable auxiliary material.
A kind of feed addictive of resisting stress that the present invention is provided includes the component of following mass fraction：Astragalus Root P.E 5-10 parts,
Haw thorn extract 10-20 parts, lysine 1-5 parts, methionine 1-5 parts, tryptophan 0.3-3 parts, threonine 0.5-2 parts, γ
- aminobutyric acid 1-5 parts, sodium acid carbonate 3-5 parts, potassium chloride 1-5 parts, vitamin C 5-10 parts, vitamin E 2-5 parts are sub-
Sodium selenate 0.01-0.02 parts, Organic Chromium 1-10 part, auxiliary material is medically acceptable composition, adds to 100 parts.
In the feed addictive of the resisting stress, described stress be fowl and animal thermal stress；The livestock and poultry be ox, pig, sheep, chicken,
Duck or goose etc., preferably chicken.
The valence state of chromium ion is trivalent in the Organic Chromium.The Organic Chromium is selected from following at least one：Chromium picolinate, cigarette
Sour chromium and yeast chromium.
In the feed addictive of the resisting stress, pharmaceutically acceptable auxiliary material can be also added；The auxiliary material is selected from as follows at least
One or more：Mannan-oligosaccharides, xylo-oligosaccharide, FOS, oligoisomaltose and sucrose compound sugar.
Further object is that providing a kind of preparation method of the feed addictive of the resisting stress.
Preparation method of the present invention comprises the steps：Each component in the feed addictive of the resisting stress is crushed respectively,
Grinding, sieve after be well mixed, the feed addictive of the resisting stress is can be prepared by after being dried.
In above-mentioned preparation method, the smashing fineness of the crushing is 80-100 mesh.
It is yet a further object of the present invention to provide a kind of using method of the feed addictive of the resisting stress.
Using method of the present invention is that anti-stress feed addictive is added into animal and fowl fodder by 0.1% mass percent
In, it is well mixed.Or be added in drinking water by 0.2% mass volume ratio, it is well mixed and is drunk for animal.
The feed of the resisting stress that the present invention is prepared by the feed addictive of the resisting stress by using method its described also belongs to
In the scope of protection of the invention.
The invention has the beneficial effects as follows：
The present invention lacks nutriment, improves animal body immunity and oxidation resistance, increasing from stress situation lower body is supplemented
Enter three aspects of animal appetite to set about, animal not only can be made quickly to recover under stress situation, while can supplement dynamic
Thing desired nutritional material, improves feed intake, reduces production loss, improves production performance.
Specific embodiment
The specific embodiment of the present invention is elaborated with reference to embodiments, but the invention is not limited in this, it is all
Any modification made within the spirit and principles in the present invention, equivalent and improvement etc. should be included in the protection of the present invention
In the range of.
Experimental technique described in following embodiments, if no special instructions, is conventional method；The reagent and material, such as without
Specified otherwise, commercially obtains.
The preparation of the anti-stress feed addictive of embodiment 1：
Each component is taken according to following ratio：Astragalus Root P.E 5g, haw thorn extract 10g, lysine 1g, methionine 1g, color
Propylhomoserin 0.3g, threonine 0.5g, GABA 1g, sodium acid carbonate 3g, potassium chloride 1g, vitamin C 5g, vitamin
E 2g, sodium selenite 0.01g, yeast chromium 1g, auxiliary material is mannan-oligosaccharides, adds to 100g.
Then, after above-mentioned each component is weighed according to aforementioned proportion, place into after agitator is thoroughly mixed, then Jing
Cross crushing (smashing fineness is 80 mesh), grinding (granularity of grinding is 90 mesh) and be dried (baking temperature is 55 DEG C) afterwards i.e.
The anti-stress feed addictive of the present invention is obtained.
The preparation of the anti-stress feed addictive of embodiment 2：
Each component is taken according to following ratio：Astragalus Root P.E 10g, haw thorn extract 20g, lysine 5g, methionine 5g,
Tryptophan 3g, threonine 2g, GABA 5g, sodium acid carbonate 5g, potassium chloride 5g, vitamin C 10g, vitamin
E 5g, sodium selenite 0.02g, nicotinate chromium 10g, auxiliary material is FOS, adds to 100g.
Then, after above-mentioned each component is weighed according to aforementioned proportion, place into after agitator is thoroughly mixed, then Jing
Cross crushing (smashing fineness is 80 mesh), grinding (granularity of grinding is 90 mesh) and be dried (baking temperature is 55 DEG C) afterwards i.e.
The anti-stress feed addictive of the present invention is obtained.
Embodiment 3
1st, the preparation of anti-stress feed addictive：
Each component is taken according to following ratio：Astragalus Root P.E 8g, haw thorn extract 15g, lysine 3g, methionine 4g, color
Propylhomoserin 0.5g, threonine 1g, GABA 3g, sodium acid carbonate 4g, potassium chloride 2g, vitamin C 8g, vitamin E 4g,
Sodium selenite 0.015g, chromium picolinate 5g, auxiliary material is xylo-oligosaccharide, adds to 100g.
Then, after above-mentioned each component is weighed according to aforementioned proportion, place into after agitator is thoroughly mixed, then Jing
Cross crushing (smashing fineness is 80 mesh), grinding (granularity of grinding is 90 mesh) and be dried (baking temperature is 55 DEG C) afterwards i.e.
The anti-stress feed addictive of the present invention is obtained.
2nd, broiler chicken high temperature feed intake and feedstuff-meat ratio contrast test：
2.1 testing programs：After 60 3 Day-old Broiler Chickens are raised one week in advance, the close broiler chicken of body weight is taken, random packet, per group 30
Only, 40 DEG C of temperature, humidity 30%, way to manage is consistent, and one group is control group, and one group is test group.
2.2 test methods：Free choice feeding and drinking-water, control group drinking-water is running water, and test group is molten for the feed addictive of 1g
Drink for chicken group after 1L water is prepared.Test period is 8 days.Two groups of feed intake in record experimental period, before on-test and
Two groups of animals are weighed after end, calculates weightening.
2.3 result of the tests：See the table below
| Group | Feed intake (g) | Weightening (g) | Feedstuff-meat ratio |
| Test group (30) | 4320 | 2057 | 2.1 |
| Control group (30) | 3645 | 1519 | 2.4 |
As a result the feed intake for showing test group is significantly higher than control group, and feedstuff-meat ratio is significantly lower than control group.Anti-stress feed adds
The using effect of agent is obvious.
3rd, under broiler chicken high temperature physiochemical indice contrast
Testing program：After 60 3 Day-old Broiler Chickens are raised one week in advance, the close broiler chicken of body weight, random packet, 30 per group, temperature
40 DEG C of degree, humidity 30%, way to manage is consistent, and one group is control group, and one group is test group.
Test method：Free choice feeding and drinking-water, control group drinking-water is running water, and test group is dissolved in 1L water for the feed addictive of 1g
Drink for chicken group after preparation.Test period is 8 days.Observed twice daily, respectively at testing 4d, 8d is at random from every
Group extracts the chicken of equal number, and blood sampling, cut open inspection, sampling claims quickly to be homogenized after weight in wet base, for the detection of enzyme activity.
Result of the test：
(1) testing result that anti-stress feed addictive affects on broiler chicks NO contents
The anti-stress feed addictive of table 1 affects on broiler chicks NO contents
Note：B is with control group than difference extremely significantly (p<0.01), following table is same.
As can be seen from Table 1, the NO contents in serum and hypothalamus are reduced with the time, resisting stress additive under same time
Compared with control group, NO contents decline pole is substantially less than control group in blood and hypothalamus.When body is subject to overstimulation,
A large amount of generations of NO can be induced, peroxynitrite (ONOO-) can be generated with the reaction of internal superoxide anion (O-2) isoreactivity oxygen
Mediated cell toxic action.Excessive ultra-oxygen anion free radical can induce a series of lipid oxidations of unsaturated fat enzyme in body
Chain reaction, causes biofilm structure and function damage, body's resistance to disease declined, had lower productivity, and causes various diseases.
(2) testing result of the anti-stress feed addictive to broiler chicks GSH-Px activity influences
The anti-stress feed addictive of table 2 is to broiler chicks GSH-Px activity influences
As can be seen from Table 2, test group and blank control group are with stress the time during serum and hypothalamic GSH-Px are active
Extend and raise, with stress reduce the prolongation of time during hypothalamic GSH-Px is active, when test group is identical with control group
Between point compare, test group declines extremely significantly (p<0.01).The special catalysis reduced form of glutathione peroxidase (CSH-PX)
Reduction reaction of the glutathione to hydrogen peroxide, the free radical such as energy scavenger-cell inner lipid Peroxidation Product (ROOH) and H2O2,
Mitigate damage of the organic hydroperoxide to body, protect the integrality of membrane structure and function, so protect body from
Damage.
Claims (8)
1. a kind of anti-stress feed addictive, it is characterised in that component includes Astragalus Root P.E, haw thorn extract, lysine, egg ammonia
Acid, tryptophan, threonine, GABA, sodium acid carbonate, potassium chloride, vitamin C, vitamin E, sodium selenite,
Organic Chromium and pharmaceutically acceptable auxiliary material.
2. a kind of anti-stress feed addictive as claimed in claim 1, the valence state that it is characterized in that chromium ion in the Organic Chromium is three
Valency, one or more combinations in chromium picolinate, nicotinate chromium, yeast chromium.
3. a kind of anti-stress feed addictive as claimed in claim 1, is characterized in that the pharmaceutically acceptable auxiliary material is sweet dew
One or more combinations in compound sugar, xylo-oligosaccharide, FOS, oligoisomaltose, sucrose compound sugar.
4. a kind of anti-stress feed addictive as described in claim 1-3 is arbitrary, including the component of following mass fraction：The Radix Astragali is carried
Take thing 5-10 parts, haw thorn extract 10-20 parts, lysine 1-5 parts, methionine 1-5 parts, tryptophan 0.3-3 parts, ammonia of reviving
Sour 0.5-2 parts, GABA 1-5 parts, sodium acid carbonate 3-5 parts, potassium chloride 1-5 parts, vitamin C 5-10 parts, dimension life
Plain E 2-5 parts, sodium selenite 0.01-0.02 parts, Organic Chromium 1-10 part, auxiliary material is medically acceptable composition, adds to 100
Part.
5. a kind of anti-stress feed addictive, its preparation method be each component in the feed addictive of the resisting stress is crushed respectively,
Grinding, sieve after be well mixed, the feed addictive of the resisting stress is can be prepared by after being dried.
6. a kind of anti-stress feed addictive as described in claim 1 to 5 is arbitrary, is characterized in that the anti-stress feed addictive
Fowl and animal thermal stress；The livestock and poultry are ox, pig, sheep, chicken, duck or goose.
7. a kind of anti-stress feed addictive as claimed in claim 6, is characterized in that for chicken heat shock.
8. a kind of anti-stress feed addictive as claimed in claim 6, is characterized in that using method is by anti-stress feed addictive
It is added in animal and fowl fodder by 0.1% mass percent, is well mixed.Or be added to by 0.2% mass volume ratio
In drinking water, it is well mixed and is drunk for animal.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510737944.1A CN106615680A (en) | 2015-11-03 | 2015-11-03 | Anti-stress feed additive |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201510737944.1A CN106615680A (en) | 2015-11-03 | 2015-11-03 | Anti-stress feed additive |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106615680A true CN106615680A (en) | 2017-05-10 |
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ID=58810551
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201510737944.1A Pending CN106615680A (en) | 2015-11-03 | 2015-11-03 | Anti-stress feed additive |
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Cited By (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107373166A (en) * | 2017-07-12 | 2017-11-24 | 华中农业大学 | A kind of finishing period meat duck anti-heat stress feed |
| CN107712319A (en) * | 2017-09-25 | 2018-02-23 | 张自力 | A kind of ruminant animal nutrition functional feedstuff additive and its production technology |
| CN107927414A (en) * | 2017-11-03 | 2018-04-20 | 佛山科学技术学院 | Compound resisting stress additive, egg duck feed suitable for laying duck cultivation |
| CN108991246A (en) * | 2018-07-31 | 2018-12-14 | 广东蔚莱生物科技有限公司 | A kind of functional form additive for farm animal feed and the preparation method and application thereof |
| CN109287881A (en) * | 2018-11-29 | 2019-02-01 | 佛山市南海东方澳龙制药有限公司 | For improving the additive and its preparation method and application of cub immunity of organisms |
| CN111513199A (en) * | 2019-12-23 | 2020-08-11 | 广州傲农生物科技有限公司 | Pig feed additive and preparation method and application thereof |
| CN114097936A (en) * | 2020-08-26 | 2022-03-01 | 河北科星药业有限公司 | Anti-stress feed additive and preparation method and application thereof |
| CN116195688A (en) * | 2023-03-16 | 2023-06-02 | 宁夏大学 | Functional feed additive for dairy cows, feed and preparation method |
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| CN101313731A (en) * | 2008-07-17 | 2008-12-03 | 北京中农博乐科技开发有限公司 | Anti-stress feedstuff additive |
| CN104222523A (en) * | 2014-09-26 | 2014-12-24 | 中国农业科学院北京畜牧兽医研究所 | Anti-stress feed additive and preparation method thereof |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107373166A (en) * | 2017-07-12 | 2017-11-24 | 华中农业大学 | A kind of finishing period meat duck anti-heat stress feed |
| CN107712319A (en) * | 2017-09-25 | 2018-02-23 | 张自力 | A kind of ruminant animal nutrition functional feedstuff additive and its production technology |
| CN107927414A (en) * | 2017-11-03 | 2018-04-20 | 佛山科学技术学院 | Compound resisting stress additive, egg duck feed suitable for laying duck cultivation |
| CN108991246A (en) * | 2018-07-31 | 2018-12-14 | 广东蔚莱生物科技有限公司 | A kind of functional form additive for farm animal feed and the preparation method and application thereof |
| CN109287881A (en) * | 2018-11-29 | 2019-02-01 | 佛山市南海东方澳龙制药有限公司 | For improving the additive and its preparation method and application of cub immunity of organisms |
| CN111513199A (en) * | 2019-12-23 | 2020-08-11 | 广州傲农生物科技有限公司 | Pig feed additive and preparation method and application thereof |
| CN114097936A (en) * | 2020-08-26 | 2022-03-01 | 河北科星药业有限公司 | Anti-stress feed additive and preparation method and application thereof |
| CN116195688A (en) * | 2023-03-16 | 2023-06-02 | 宁夏大学 | Functional feed additive for dairy cows, feed and preparation method |
| CN116195688B (en) * | 2023-03-16 | 2024-02-13 | 宁夏大学 | Functional feed additive for dairy cows, feed and preparation method |
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