CN106482302A - The automatic monitoring system of pharmaceutical manufacturing environment - Google Patents

The automatic monitoring system of pharmaceutical manufacturing environment Download PDF

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Publication number
CN106482302A
CN106482302A CN201611021850.5A CN201611021850A CN106482302A CN 106482302 A CN106482302 A CN 106482302A CN 201611021850 A CN201611021850 A CN 201611021850A CN 106482302 A CN106482302 A CN 106482302A
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CN
China
Prior art keywords
air
main control
pharmaceutical manufacturing
detection device
manufacturing environment
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Pending
Application number
CN201611021850.5A
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Chinese (zh)
Inventor
刘振峰
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yichun Wanshen Pharmaceutical Machinery Co Ltd
Original Assignee
Yichun Wanshen Pharmaceutical Machinery Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Yichun Wanshen Pharmaceutical Machinery Co Ltd filed Critical Yichun Wanshen Pharmaceutical Machinery Co Ltd
Priority to CN201611021850.5A priority Critical patent/CN106482302A/en
Publication of CN106482302A publication Critical patent/CN106482302A/en
Pending legal-status Critical Current

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Classifications

    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F2110/00Control inputs relating to air properties
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F11/00Control or safety arrangements
    • F24F11/0008Control or safety arrangements for air-humidification
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F11/00Control or safety arrangements
    • F24F11/30Control or safety arrangements for purposes related to the operation of the system, e.g. for safety or monitoring
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F11/00Control or safety arrangements
    • F24F11/62Control or safety arrangements characterised by the type of control or by internal processing, e.g. using fuzzy logic, adaptive control or estimation of values
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F2110/00Control inputs relating to air properties
    • F24F2110/10Temperature
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F2110/00Control inputs relating to air properties
    • F24F2110/20Humidity
    • FMECHANICAL ENGINEERING; LIGHTING; HEATING; WEAPONS; BLASTING
    • F24HEATING; RANGES; VENTILATING
    • F24FAIR-CONDITIONING; AIR-HUMIDIFICATION; VENTILATION; USE OF AIR CURRENTS FOR SCREENING
    • F24F2110/00Control inputs relating to air properties
    • F24F2110/50Air quality properties
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02BCLIMATE CHANGE MITIGATION TECHNOLOGIES RELATED TO BUILDINGS, e.g. HOUSING, HOUSE APPLIANCES OR RELATED END-USER APPLICATIONS
    • Y02B30/00Energy efficient heating, ventilation or air conditioning [HVAC]
    • Y02B30/70Efficient control or regulation technologies, e.g. for control of refrigerant flow, motor or heating

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  • Engineering & Computer Science (AREA)
  • Combustion & Propulsion (AREA)
  • General Engineering & Computer Science (AREA)
  • Mechanical Engineering (AREA)
  • Chemical & Material Sciences (AREA)
  • Atmospheric Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Quality & Reliability (AREA)
  • Physics & Mathematics (AREA)
  • Fuzzy Systems (AREA)
  • Mathematical Physics (AREA)
  • Signal Processing (AREA)
  • Air Conditioning Control Device (AREA)

Abstract

The invention discloses a kind of automatic monitoring system of pharmaceutical manufacturing environment.The input detection device including main control computer, being connected to described main control computer and corresponding output device, described input detection device includes temperature detector and moisture detector, described input detection device also includes an Analysis On Gaseous Constituentss device, described temperature detector, moisture detector and gas ingredient analysis device are connected to a data acquisition unit, and described data acquisition unit outfan is connected to described main control computer.It can system, comprehensively, intactly effective monitoring management and control are carried out to pharmaceutical manufacturing environment, be capable of the real-time monitoring of workshop humiture and air quality etc. and automatically control.

Description

The automatic monitoring system of pharmaceutical manufacturing environment
Technical field
The present invention relates to a kind of automatic monitoring system of pharmaceutical manufacturing environment.
Background technology
Pharmaceutical production is different from the production of general merchandise, and what it was directly related to is the life security of people, according to related medicine The regulation of quality of production management regulation, it has and its strict regulation to the production environment manufacturing medicine.For non-sterile medicine The production environment of product (fingering determines the preparation of non-row sterility test project in drug standard) not only has necessarily to temperature and humidity Requirement, particularly also have strict requirements to ambient air quality, higher to the purity requirements of air.And these environment shapes It is to require far from meeting that the factor of condition is only passed through manually to carry out intermittent detection and selective examination, or the warp of the people that places one's entire reliance upon The epidemic disaster tested and the control of air quality, random big, epidemic disaster and the environmental gas quality control in whole workshop will be made Unstable properties processed, fluctuation is larger.Also cannot in real time, accurately and fast show simultaneously and transmit these parameter informations.Existing adopt With detection means such as some instrument and meters, but due to reasons such as performance and occupation modes it is impossible to formed system to production environment Carry out comprehensive, objective and effective monitoring management to control, thus its effect is unsatisfactory.
Content of the invention
The purpose of the present invention is the problem existing for prior art, provides a kind of automatic monitoring of pharmaceutical manufacturing environment System processed.It can system, comprehensively, intactly effective monitoring management and control are carried out to pharmaceutical manufacturing environment, be capable of The real-time monitoring of workshop humiture and air quality etc. and automatically controlling.
The technical scheme of the automatic monitoring system of pharmaceutical manufacturing environment of the present invention includes main control computer, connects respectively In input detection device and the corresponding output device of described main control computer, described input detection device includes temperature detector And moisture detector, described input detection device also includes an Analysis On Gaseous Constituentss device, described temperature detector, moisture detector It is connected to a data acquisition unit with gas ingredient analysis device, described data acquisition unit outfan is connected to described master control and calculates Machine.
Described output device includes humidifier and corresponding alarm device, and described humidifier and alarm device are connected to Described main control computer.
Described Analysis On Gaseous Constituentss device includes gas chromatograph.
The present invention is capable of pharmaceutical manufacturing workshop, the real-time monitoring including epidemic disaster etc. in place and automatically controls, and The operational efficiency of raising air-conditioner system, the energy that minimizing air-conditioner system consumes, high degree of automation, each under production environment Control parameter can mutually take into account, mutually coordinated, and it has preferably comprehensively environment epidemic disaster, air quality etc. relatively Regulating effect, and the operational efficiency of air regulation equipment can be improved, reduce the energy resource consumption of relevant device.
Brief description
Fig. 1 is the structured flowchart of automatic monitoring system one embodiment of this pharmaceutical manufacturing environment.Fig. 2 is the present invention's Air conditioner fault detection means one example structure block diagram.Fig. 3 is the Temperature and Humidity circuit structure in one embodiment of the invention Schematic diagram.Fig. 4 is the Wireless communication circuit structure schematic diagram of the present invention.Fig. 5 is that the intelligent substitution line in invention unifies embodiment Structural representation.Fig. 6 is the intelligent power saving operating control device structured flowchart in the present invention.
Specific embodiment
For having a better understanding of the present invention, combine accompanying drawing by the following examples and the principle of the present invention and feature are entered Row description.As shown in Fig. 1-2, the system includes temperature detector 1, moisture detector 2, data acquisition unit 3, humidifier 5, leads to News machine 6, air-conditioner 7, Analysis On Gaseous Constituentss device and main control computer 4 etc..Main control computer 4 is connected with touch display screen 8 and report Alert device 10.Temperature detector 1, moisture detector 2 are all connected with data acquisition unit 3 input, the outfan of data acquisition unit 3 It is connected with main control computer 4, main control computer 4 is also connected with humidifier 5, radio communication circuit 6 etc. respectively.Described alarm 10 can be audible-visual annunciator.Analysis On Gaseous Constituentss device is a gas chromatograph 9.
It passes through epidemic disaster detector and gas ingredient analysis device(Gas chromatograph)Measure current pharmaceutical manufacturing room in real time The temperature humidity of interior environment and air quality situation, the relevant parameter of its detection can be transported to master control by data acquisition unit and calculate Machine, is carried out after comprehensive calculation process by corresponding detection parametric synthesis analysis module by main control computer, goes to control accordingly The output device such as air-conditioner and humidifier is implemented to run, and is monitored with the indoor environment to Workplace and controls.Same phase The result closing detection data and main control computer can be sent to remote terminal, far by its communication module, bottom-layer network The computer-implemented remote monitoring of journey, also can carry out being wirelessly transmitted to phase by corresponding communication module and radio communication circuit The termination answered.The data of each input detector detection, can sound and light alarm on the spot when surmounting the bound controlling value of setting Report to the police etc. mode, also can remote alarmss.The system can be carried out to the relevant parameter of system and video data by touch display screen Set and handover operation.
The system also includes an air conditioner fault detection means, and its main control computer is additionally provided with an air-conditioner operation troubles Detection module.Air conditioner fault detection means includes air-conditioning remote controller 22, shakes control signal receiving circuit 23, and the described control signal that shakes connects Receive the air-conditioner operation troubles detection module that circuit is connected to main control computer 4, mould is detected by main control computer operation troubles Block carries out operation troubles detection to air-conditioner.Its concrete fault detect includes:When not freezing fault occurs in air-conditioning, will automatically examine Measure fault.User is turned on the aircondition refrigeration with remote control console keyboard, is got by the infrared receiving terminal shaking control signal receiving circuit and shakes control Operation signal, through air-conditioner operation troubles detection module decoding get the configuration information to air-conditioning for the user.Program is recorded Current real-time time and current ambient temperature and humidity, air-conditioner operation troubles detection module are got by temperature and humidity sensing chip Obtain a humiture every 5-20 minute, when air-conditioning breaks down and do not freeze, ambient temperature will not substantially or will not be by Normal descent rate declines, if continuously 1-3 hour detection environment actual temperature never has decline, illustrates that event in air-conditioning Barrier.I.e. the intelligent power saving operating control device of air-conditioning finds fault automatically.
In the system embodiment 2.Its temperature detector and moisture detector are by a Temperature Humidity Sensor chip as shown in Figure 3 Constitute with corresponding peripheral circuit etc..Temperature and Humidity circuit mainly includes model SHT20 Temperature Humidity Sensor chip U2, temperature The foot 1 of humidity sensor chip U2 and foot 6 are connected respectively foot 16 and 15, foot in microprocessor.By Temperature Humidity Sensor Chip U2 is transmitted data to micro- by the foot 1 of Temperature Humidity Sensor U2, foot 6 after getting air-conditioning indoor environment epidemic disaster value The foot 16 of processor U1, foot 15, microprocessor U1 is getting production indoor environment epidemic disaster value, the control of main control computer 4 Model or program do respective handling control according to this warm and humid angle value.Remaining structure of this example and corresponding control mode can be with above-mentioned realities Apply example similar.
In the embodiment 3 of the system.As shown in figs. 1 and 4, its wireless communication line includes corresponding microprocessor U1 electricity Road, and the impedance matching circuit being made up of corresponding inducer and capacitor.Wireless communication signal is produced by microprocessor U1 Afterwards, arrive the wireless signal transceiving chip of model CC2591 again to output winding L1, L8 by the foot 25 of microprocessor U1, foot 26 The foot 2 of U5, foot 4, wireless communication signal exports from its foot 11 after wireless signal transceiving chip U5 amplification, through impedance matching electricity Road L13, C7, C8, C9 are coupled on antenna A1, by antenna, wireless communication signal are issued to receiving device, and receiving device will Communication data shows on the computer or mobile phone of user.
Wireless communication signal is produced by U1, arrives 2,4 feet of U5, wireless communication signal again by the 25 of U1,26 feet to L1, L8 Export from 11 feet after U5 amplifies, be coupled on corresponding antenna through L13, C7, C8, C9 impedance matching, will no by antenna Line communication signal sends.Remaining structure of this example and corresponding control mode can be similar with any of the above-described embodiment.
In the embodiment 4 of the system.As shown in figure 5, it is provided with intelligent exchange system accordingly, intelligence corresponding to air-conditioner 7 Energy exchange system carries out fresh air with an intermittent duty to the pharmaceutical manufacturing indoor environment under conditioners running conditions and puts Change.Intelligent exchange system includes being opened in the extraneous air air inlet 12 of Workplace interior 11 and located at Workplace interior Corresponding exhaust fan 13, its main control computer 4 is provided with corresponding replacement module, and main control computer 4 passes through its replacement module and sky Device 7 is adjusted to connect, main control computer also can connect a corresponding infrared signal device, and replacement module is filled by corresponding infrared signal Put and be connected with air-conditioner 7 by the IR remote controller of air-conditioner 7 with infrared signal simultaneously.
The air inlet 12 of Workplace interior 11 is provided with air filter 16.The extraneous air of its Workplace interior 11 Air inlet 12 can be the wall perforate of the indoor and outdoor machine of air-conditioner 7 and the connecting line of indoor set.
After replacement module detects air-conditioner 7 unlatching by corresponding infrared remote-controlled signal and/or electrical signal line, output One control signal controls exhaust fan to turn on into working condition, and exhaust fan runs and makes indoor 11 environment be in negative pressure state, empty Adjust outdoor fresh air(Fresh air)Got in by indoor 11 extraneous air air inlet in the presence of external differential indoors.This Remaining structure of example and corresponding control mode can be similar with any of the above-described embodiment.
In the embodiment 5 of the system.Its main control computer is connected with an intelligent switch by corresponding intelligent gateway signal, Described exhaust apparatus is connected with this intelligent switch signal of telecommunication.Remotely control is realized by outer computer or RTU.
In the embodiment 6 of the system.As shown in fig. 6, also including intelligent power saving operating control device, its main control computer bag Include an intelligent power saving operation control module, described intelligent power saving operating control device includes shaking control signal reception and radiating circuit, Shake control signal reception and power consumption testing circuit, ambient temperature and humidity testing circuit and/or the operation of radiating circuit corresponding to described Real-time time circuit.
It is provided with corresponding to described intelligent power saving operation control module and shakes control signal reception and radiating circuit, shake corresponding to described Control signal receives and radiating circuit is provided with power consumption testing circuit 32, ambient temperature and humidity testing circuit and/or runs real-time time Circuit 31.Power consumption testing circuit 32 is connected to main control computer(Intelligent power saving operation control module)With air-conditioner 7.
Shake control signal receiving circuit 33, ambient temperature and humidity testing circuit 1,2 and operation real-time time circuit 31 to connect respectively In the corresponding input of this intelligent power saving operation control module, shake control signal transmission circuit 34 and be connected to the operation of this intelligent power saving The corresponding outfan of control module.
Main control computer(Intelligent power saving operation control module)With output control signal, air-conditioner can be controlled accordingly System.Can also be connected with humidifier by corresponding holding wire, so that control is accordingly run to it simultaneously.
Shaking control signal transmission circuit is one infrared yard of radiating circuit, and this infrared code radiating circuit includes infrared transmitting tube, red Outer carrier signal generator, infrared pulse modulation signal generator and corresponding signal hybrid modulation device.
It arranges one with the operation run action of air-conditioner, power consumption, air conditioning chamber in intelligent power saving operation control module The real-time time of interior environment epidemic disaster and/or operation of air conditioner or period are foundation or the energy-saving operation of air conditioner control program of variable Or model, by this intelligent power saving operation control module, basis shakes reflection or the expression air-conditioning that control signal receiving circuit 33 inputs respectively Reflection or the consumption representing air-conditioning that the run action signal of the action being run by operation, power consumption testing circuit 32 input(With)Electricity The ambient temperature and humidity signal of amount signal, the reflection of pharmaceutical manufacturing indoor environment Temperature and Humidity device input or expression indoor environment, And/or run residing for the reflection air-conditioning of real-time time circuit 6 input run period or run time operation real-time(Or run Period)Time signal carries out saving-energy operation control or carries out saving-energy operation control and fault diagnosis to air-conditioning to air-conditioning;And then Make operation of air conditioner in not only making one to feel comfortably cool but also the optimal operational condition of energy saving.Simultaneously can also be according to the power of air-conditioning Expenditure Levels and operation conditions make breakdown judge to air-conditioning.To instruct timely maintenance and repair.Remaining structure of this example is with accordingly Control mode can be similar with any of the above-described embodiment.
In the embodiment 7 of the system.Its main control computer is also associated with a power consumption amount detecting device, power consumption amount detecting device For power consumption testing circuit, it includes appliance power and power consumption testing circuit, the power of described electrical equipment and power consumption detection electricity Road includes sample circuit, the operation result of measurement circuit being connected with sample circuit, and described operation result of measurement circuit includes power and power consumption Detection chip, described sample circuit is connected to the corresponding input of this power and power consumption detection chip, by described measurement fortune Calculate circuit or its power and power consumption detection chip exports power and the power consumption signal representing corresponding electrical equipment respectively.
Its sample circuit includes sample resistance, and described sample resistance is connected to described power and the phase of power consumption detection chip The input answered, the outfan of described power and power consumption detection chip is connected with spacing output circuit, by described isolation and amplifier The corresponding outfan of circuit exports power and the power consumption signal representing described electrical equipment respectively.With the operation electricity to air-conditioner Consumption carries out monitor in real time.Remaining structure of this example and corresponding control mode can be similar with any of the above-described embodiment.

Claims (3)

1. a kind of automatic monitoring system of pharmaceutical manufacturing environment, including main control computer, is connected to described master control meter The input detection device of calculation machine and corresponding output device, described input detection device includes temperature detector and Humidity Detection Device, is characterized in that described input detection device also includes an Analysis On Gaseous Constituentss device, described temperature detector, moisture detector and Gas ingredients detector is connected to a data acquisition unit, and described data acquisition unit outfan is connected to described master control and calculates Machine.
2. require the automatic monitoring system of pharmaceutical manufacturing environment described in 1 according to claim, it is characterized in that described output dress Put including humidifier and corresponding alarm device, described humidifier and alarm device are connected to described main control computer.
3. require the automatic monitoring system of pharmaceutical manufacturing environment described in 1 according to claim, it is characterized in that described gas becomes Part analyzer includes gas chromatograph.
CN201611021850.5A 2016-11-21 2016-11-21 The automatic monitoring system of pharmaceutical manufacturing environment Pending CN106482302A (en)

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CN201611021850.5A CN106482302A (en) 2016-11-21 2016-11-21 The automatic monitoring system of pharmaceutical manufacturing environment

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Application Number Priority Date Filing Date Title
CN201611021850.5A CN106482302A (en) 2016-11-21 2016-11-21 The automatic monitoring system of pharmaceutical manufacturing environment

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CN106482302A true CN106482302A (en) 2017-03-08

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109885014A (en) * 2019-04-10 2019-06-14 苏州洽友信息科技有限公司 A kind of medicament compartment intelligent monitor system
CN112241154A (en) * 2020-10-15 2021-01-19 杭州澳亚生物技术有限公司 Intelligent monitoring management system for GMP workshop

Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002267206A (en) * 2001-03-13 2002-09-18 Takasago Thermal Eng Co Ltd Air-cleaning air-conditioning method and air-cleaning air conditioner
CN104596041A (en) * 2015-02-08 2015-05-06 宜春市脉恩多能科技有限公司 Intelligent energy-saving operation control device of air conditioner and control method thereof
CN104819510A (en) * 2015-05-06 2015-08-05 杭州钛合智造电器有限公司 Intelligent air purification control system and method
CN105737299A (en) * 2014-12-12 2016-07-06 陕西银河网电科技有限公司 Multifunctional air purifier
CN206572703U (en) * 2016-11-21 2017-10-20 宜春万申制药机械有限公司 A kind of automatic monitoring system of pharmaceutical manufacturing environment

Patent Citations (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2002267206A (en) * 2001-03-13 2002-09-18 Takasago Thermal Eng Co Ltd Air-cleaning air-conditioning method and air-cleaning air conditioner
CN105737299A (en) * 2014-12-12 2016-07-06 陕西银河网电科技有限公司 Multifunctional air purifier
CN104596041A (en) * 2015-02-08 2015-05-06 宜春市脉恩多能科技有限公司 Intelligent energy-saving operation control device of air conditioner and control method thereof
CN104819510A (en) * 2015-05-06 2015-08-05 杭州钛合智造电器有限公司 Intelligent air purification control system and method
CN206572703U (en) * 2016-11-21 2017-10-20 宜春万申制药机械有限公司 A kind of automatic monitoring system of pharmaceutical manufacturing environment

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN109885014A (en) * 2019-04-10 2019-06-14 苏州洽友信息科技有限公司 A kind of medicament compartment intelligent monitor system
CN112241154A (en) * 2020-10-15 2021-01-19 杭州澳亚生物技术有限公司 Intelligent monitoring management system for GMP workshop

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