CN106457272A

CN106457272A - Flushing dispensers for delivering consistent consumer experience

Info

Publication number: CN106457272A
Application number: CN201580030737.0A
Authority: CN
Inventors: L·巴罗韦; N·C·德林; E·A·M·巴克斯特; M·J·克哈诺卡; J·C·普洛斯; A·R·E·麦格雷戈; J·O·迪霍拉; A·G·霍瓦斯
Original assignee: Procter and Gamble Ltd
Current assignee: Procter and Gamble Ltd; Procter and Gamble Co
Priority date: 2014-06-09
Filing date: 2015-06-09
Publication date: 2017-02-22
Also published as: EP3151976A1; WO2015191495A1; BR112016028703A2

Abstract

A process for flushing a dispenser and a process for combining a first composition and a second composition to form a mixture and dispensing said mixture through an exit orifice are provided. Assemblies for flushing are also provided.

Description

For delivering the flushing distributor of satisfied consumer experience

Technical field

The disclosure relates generally to method and assembly for rinsing distributor.

Background technology

Consumer it is generally desirable to deliver the fragrance of pleasant during and/or after products applied.This type of aromatic leads to Often comprise perfumery oil and/or provide finite time fragrance other distribute aroma substance.Comprise for solubilising aromatic oil and/or its The solvent that it distributes aroma substance is also not rare.Sometimes, this kind solvent may with other of benefit can be provided to become for consumer Divide incompatible.Although can there is the distributor including for making incompatible composition separate chambers separately, but this type of distributor can Can cannot provide satisfied experience for consumer, or special component may not be distributed and do not damage and/or choke system.Cause This, need a kind of distributor making some incompatible compositions be held apart at simultaneously delivering satisfied experience for consumer.

Content of the invention

A kind of method for rinsing distributor 10, described method includes：By distributor 10 and the assembly 399 being used for flushing In conjunction with it provides for by the first composition 51 from the first reservoir 50 and the second composition from the second reservoir 60 61 are pumped into the first stage of at least one and second stage in minor air cell 130 and premixer 150；Wherein in phase first stage Between, the first composition 51 and the second composition 61 substantially simultaneously pump from the first reservoir 50 and the second reservoir 60 and enter At least one in minor air cell 130 and premixer 150；Wherein during second stage, the first composition 51 and the second composition One in 61 stops pumping, and the one in the first composition 51 and the second composition continues pumping simultaneously, thus will rinse body Long-pending (V1) is pumped at least one in minor air cell 130 and premixer 15；Wherein the first stage occurred before second stage.

First composition 51 is mixed to form mixture and by described in outlet 40 distribution by one with the second composition 61 The method of mixture, described method includes：There is provided distributor 10, described distributor includes for described storage the first composition 51 The first reservoir 50 and for storing the second reservoir 60 of described second composition, described distributor also includes and described the First pump 90 of one reservoir 50 fluid connection and the second pump 100 with described second reservoir 60 fluid connection, described first Pump 90 and the second pump 100 each with premixer 150 fluid connection, described premixer 150 connects with exporting 40, optionally by whirlpool Flow chamber 130 simultaneously exports 40 from there through described；Wherein said distributor also includes for substantially simultaneously operating described first pump 90 and the assembly 399 of described second pump 100, to provide the second composition of the first composition 51 of the first volume and the second volume 61 deliverys to described premixer 150, thus form mixture and distribute institute via described outlet 40 from described premixer 150 State mixture；Wherein during the formation of described blend compositions, the one in the first volume and the second volume stops delivering, by The corresponding composition continuation of this final non-mixed volume V1 is individually delivered in premixer 150 residual to rinse in premixer 150 Any remaining blend compositions staying, and be optionally delivered in minor air cell 130, by outlet 40 outflow.

Brief description

Although this specification is using claims as ending, but believe by description below and combine accompanying drawing can be more preferably geographical Solve the present invention, wherein：

Fig. 1 is the front view of distributor；

Fig. 2 is the sectional view of distributor side；

Fig. 3 is the anterior sectional view of distributor；

Fig. 3 A is the anterior sectional view of distributor；

Fig. 3 B is the anterior sectional view of distributor；

Fig. 4 is the sectional top view of distributor；

Fig. 4 A is the amplification view of Fig. 4 inner region；

Fig. 5 is the perspective cut-away schematic view of dispenser top；

Fig. 5 A is the top perspective sectional view of distributor and does not shows minor air cell；

Fig. 5 B is the perspective cut-away schematic view of minor air cell；

Fig. 6 is the sectional top view of distributor；

Fig. 6 A is the section of Fig. 6 inner region；

Fig. 6 B is the amplification view of Fig. 6 inner region；

Fig. 7 is the front view of the assembly for distributor；

Fig. 8 is the anterior sectional view of distributor；

Fig. 8 A is the anterior sectional view of distributor；

Fig. 8 B is the anterior sectional view of distributor；

Fig. 8 C is the anterior sectional view of distributor；

Fig. 9 is the front view of the assembly for distributor；

Figure 10 is the anterior sectional view of distributor；

Figure 10 A is the anterior sectional view of distributor；

Figure 10 B is the anterior sectional view of distributor；

Figure 10 C is the anterior sectional view of distributor；

Figure 11 is the sectional view of distributor side；

Figure 11 A is the sectional view of distributor side；

Figure 11 B is the sectional view of distributor side；

Figure 12 is the perspective view of the assembly for distributor；

Figure 12 A is the side view of the assembly for distributor；

Figure 13 is the sectional view at distributor rear portion；

Figure 13 A is the sectional view of distributor side；

Figure 13 B is the amplification view of Figure 13 A inner region；

Figure 13 C is the sectional view at distributor rear portion；

Figure 13 D is the sectional view at distributor rear portion；

Figure 13 E is the sectional view at distributor rear portion；

Figure 14 is the perspective view of dispenser top；

Figure 14 A is the side view of dispenser top；

Figure 15 is the sectional view of distributor side；

Figure 15 A is the partial sectional view of distributor；

Figure 16 is the sectional top view of distributor；

Figure 16 A is the sectional view of distributor side；

Figure 17 is the sectional top view of distributor；

Figure 17 A is the partial sectional view of dispenser top；

Figure 17 B is the amplification view of Figure 17 inner region；

Figure 18 is the partial rear view of minor air cell；

Figure 18 A is the lateral side view of minor air cell；

Figure 18 B is the front perspective view of minor air cell；

Figure 19 is the sectional view of distributor side；

Figure 20 is the sectional view of distributor side；

Figure 21 is the sectional view of distributor side；And

Figure 22 is the section rear view of distributor.

Detailed description of the invention

Except as otherwise noted, all percentages and percentage by weight are based on the weight of composition.Unless additionally said especially Bright, all ratios is weight ratio.All number ranges are the narrower ranges including end value；Described range limit and model It is interchangeable for enclosing lower limit, to form other scopes being not explicitly described.The numeral of number of significant digit neither limits indicated amount Certainty of measurement is not limited yet.All measurements are all understood to carry out under about 25 DEG C and environmental condition, wherein " environment bar Part " refer to about atmospheric pressure and about 50% relative humidity under condition.

As used herein, " composition " refers to be suitable to locally apply to the composition on mammalian keratinous tissue.This type of group Compound is equally applicable to yarn fabric or the clothes of any other form, including but not limited to by synthetic fibers such as nylon and polyester system The clothes becoming, and by acetic acid esters, bamboo, ammonia copper wire, hemp, flannel, jute, Lyocell fibers, PVC-polyvinyl chloride, artificial The clothes that silk, regrown material, rubber, soybean, Tyvek, cotton and other natural fibers are made.

" export " passage being shown as from minor air cell to external environment condition herein.

" not containing " refers to that illustrated composition is not added in composition.But, illustrated composition may be attached Be formed as accessory substance or the product of other components of composition with ground.

" rinse " or " washing away " refer to when distributor provides the flowing in two stages in distributor produce result, its In in the first phase two pumps be provided which the delivery of its correspondent composition, only one pump base in the second stage carrying out afterwards The operative strokes running through its piston in basis continues delivering compositions.Its non-limiting example includes：Comprising the combination of microcapsules After the mixture of thing or the composition comprising volatile solvent and microcapsules flows into distributor so that comprise volatile solvent Composition continues flowing.

" non-volatile " refers to have at ambient conditions that can measure vapour pressure in liquid or solid and at 25 DEG C A little materials.These materials are typically below the vapour pressure of about 0.0000001mmHg, and generally greater than about 250 DEG C average Boiling point.

" solubility " refers to that the solute of at least about 0.1g is dissolved in the solvent of 100mL under the pressure of 25 DEG C and 1atm.

Substantially free represents based on the weight of composition, and the amount of material is less than the 1%th, the 0.5%th, the 0.25%th, the 0.1%th, 0.05%th, 0.01% or 0.001%.

As used herein, " derivative " including but not limited to gives the acid amides of chemicals, ether, ester, amino, carboxyl, acetyl Base and/or 01 derivatives.

As used herein, " skin care actives " refers to when being coated on skin to provide benefit or improvement to skin Compound.It should be appreciated that described skin care actives cannot be only used for being administered on skin, and hair can be administered to, refer to/toe In first and other mammalian keratinous tissues.

Except as otherwise noted, as used herein, " volatility " refers at ambient conditions in liquid or solid and at 25 DEG C Under there are those materials that can measure vapour pressure.These materials are generally of greater than about 0.0000001mmHg or about The vapour pressure of 0.02mmHg to about 20mmHg, and the mean boiling point of generally less than about 250 DEG C or less than about 235 DEG C.

Fine fragrance such as Gulong perfume and perfume are generally consumer institute because it can deliver the fragrance of pleasant Expect.This type of fine fragrance disadvantageously, because aromatic is typically volatile, so consumer may must be very Fine fragrance is applied again, so that the fragrance distributing keeps identical after short a period of time.Although consumer it may be desirable to There is conspicuousness duration longer fine fragrance product, but seem not exist and extend the simple of conspicuousness duration Solution.Therefore, the many fine fragrance product utilizations on market include the ancient system of volatile solvent and aromatic oil, The conspicuousness of described system the commonly provided short period.

It is that controlled release system is introduced product for increasing a method of aromatic conspicuousness duration in product.With regard to this For a bit, make microcapsules be included in specific products such as deodorant, thus delay release in headroom for the aromatic.So And, in composition, the stability of microcapsules can be affected by composition in composition.For example, some compositions may result in microcapsules can not Keep its integrality or the aromatic of encapsulating can not be made to elapse in time reach specified level degree.

It has been observed that volatile solvent such as ethanol can severely impact the microcapsules loading aromatic present in composition The aromatic encapsulated is discharged into the ability in headroom.Surprisingly it has been discovered that minimize microcapsules and volatility Time of contact between solvent (such as ethanol) enables microcapsules to deliver obvious benefit for consumer.This can be by making Realizing with distributor, this distributor has at least two reservoir, and one is used for storing volatile solvent and another use In storage microcapsules and carrier thereof.

It was additionally observed that, including multiple known dispenser of at least two reservoir can not deliver come from the aobvious of microcapsules and Be clear to is satisfied with benefit.For example, some distributors with more than one reservoir may make microcapsules and volatile solvent mistake Early mixing, this may result in obstruction and/or causes damage to microcapsules itself.In this regard, some have more than one The distributor of reservoir can be at the two kinds of compositions (from each reservoir) exporting somewhere holding significant quantity between reservoir Mixture, this make next time activate may produce comprise impaired microcapsules mixture.The impaired microcapsules of this type of remnants are also Can accelerate to block.For example, some distributors can keep the composition to be allocated of based on the weight of sendout up to 100%, and this takes The certainly design between outlet and reservoir.In addition, too much power may be put on during assigning process by some distributors Microcapsules so that the microcapsules of significant quantity discharge its content too early.Because microcapsules and the incompatibility of volatile solvent, institute Unsatisfied olfactory sensations can be delivered with this type of distributor to consumer.

Another prominent question that can exist itself is, can be used for the carrier of microcapsules and can have higher surface and open Power so that the composition comprising microcapsules is anti-fog.For example, when carrier is water, (at 20 DEG C, 73 reach high capillary water Because of/centimetre) can be anti-fog so that stream is more likely distributed rather than is sprayed.Introduce suspending agent for microcapsules and can be further exacerbated by this Problem, because suspending agent can increase the viscosity of the composition comprising water and microcapsules so that described composition can overcome it relative The possibility that high surface tension is atomized is less.It is well known that there is the composition of high surface tension and viscosity higher It is difficult to be atomized in the case of not producing notable pressure.If composition not with abundant atomization distribution, then this type of distributor for High-end product such as fine fragrance may be inadvisable.

In this regard, when the second composition comprises volatile solvent and the first composition comprises water, in flight The distributor of two kinds of compositions of middle mixing (i.e. composition is held apart at and via different outlet distribution in whole distributor, The angle of outlet of every kind of composition causes two kinds of compositions to mix in atmosphere) unlikely useful, reason is the combination comprising water Thing is anti-fog.In this type of design, it is possible to, the composition comprising volatile solvent is aerosolizable and the combination that comprises water Thing is by anti-fog；Thus cause presenting to user as thread in sprayer.If it occur that this type of result, then this type of distribution Device may be inadvisable for high-end product such as fine fragrance.

Distributor

In order to prevent remnants impaired microcapsules accumulate within distributor, distributor as herein described be customized to so that Component of mixture can rinse, to remove any remaining microcapsules contacting with volatile solvent.These remaining microcapsules are one Can accelerate in the case of Xie to block.Remaining microcapsules also can exit or near leave ugly residue, this is for fine fragrant Material product is less desirable.Without being limited by theory, it is believed that the concentration of microcapsules used and type can cause in some cases Distributor blocks.In order to alleviate these problems, distributor may be tailored to include the assembly 399 for rinsing.This document describes point Some non-limiting examples of orchestration.

Flushing can be realized by several different designs.But, all described designs make use of conventional method.The method depends on Relying at least two pump, two of which pump provides the delivery of its correspondent composition in first " productivity " during the stage.Then, when When one pump continues delivering compositions to provide flush volume (V1) to rinse minor air cell's (and other possible components), another Individual pump enters " unproductive " stage, wherein this pump substantially no longer delivering compositions.In some instances, flush volume (V1) Should be enough to flow the element of distributor of the mixture by being exposed to the first composition and the second composition.In some examples In, if the volume that the volume of minor air cell, premixer and outlet is 12 microlitres, then V1 should be more than or equal to 12 microlitres.In order to really Protect distributor to be minimized by the amount making to stay the residual mixture in distributor after each actuation events and provide satisfied Consumer experience, when the volume of distribution is about 30 microlitres to about 300 microlitre, the volume of V1 should be micro-to about 50 at about 5 microlitres In the range of liter.

It should be appreciated that the assembly 399 for rinsing can play use with premixer 150-as described herein.Alternatively, when When composition is delivered directly to minor air cell 130, the assembly 399 for rinsing can be used.Alternatively, when composition is directly passed When delivering to export 40, the assembly 399 for rinsing can be used.

Distributor disclosed herein can provide the aromatic conspicuousness of satisfied consumer experience and long period.Herein Described distributor makes minimize the time of contact between microcapsules and volatile solvent (such as ethanol), so that microcapsules energy Enough deliver obvious benefit for user.Distributor described herein includes at least two reservoir, and a reservoir is used for Individually store the one in the first composition and the second composition.Distributor may also include the whirlpool for making two kinds of composition atomizations Flow chamber.First and second compositions leave distributor via shared outlet.Distributor is also with at least two and is furnished with piston Pump, a pump is for pumping the first composition, and the second pump is for being pumped to the second composition share minor air cell and outlet. Respective composition is pumped into for composition is delivered to minor air cell and at least one outlet from reservoir by each pump Passage.

In some instances, distributor described herein can by premixer 150 first blend compositions and face from Two kinds of composition mixing are made before opening.Premixer 150 can have the sendout that be enough to comprise 1% to 100% volume, or 1% To the sendout of 75%, or 2% to 20% sendout, or the volume of the sendout of 4% to 14%.In some examples In, in order to make distributor produce satisfied consumer experience, preferably limit the volume of premixer, because this type of design will limit The degree of the impaired microcapsules being sprayed from distributor during each actuation events.It is below non-limiting example：If divided The of first composition that cumulative volume is 105 microlitres and institute's distributive mixing thing comprises about 35 microlitres of compounding compound and 70 microlitres Two compositions, then premixer 150 can have the body of blended first and second compositions that be enough to mix 5 microlitres to 15 microlitres Long-pending.In some instances, premixer can include one or more deflector (not shown), with turbulization and improve mixing.

Mixing in premixer 150 as described herein provides some advantages.First, the distributor of this paper make use of with The lower fact：Specific volatile solvent (such as ethanol) causes mixture to have the surface tension lower than water with the mixture of water, this Increase the possibility making two kinds of compositions suitably be atomized.Second, by limiting the duration mixing and degree, microcapsules It is not easy to impaired when leaving.3rd, limit the duration of mixing and degree also makes obstruction can energy minimization.Finally, lead to Crossing the amount minimum making to stay the residual mixture in distributor after each actuation events, the design of this paper provides satisfaction Consumer experience.

The size of distributor can as a example by if hand-held.Distributor can include the first combination being stored in the first reservoir Thing, and the second composition being stored in the second reservoir.Second composition can comprise volatile solvent and the first aromatic. First composition can comprise multiple microcapsules and carrier (such as water).First composition also can comprise suspending agent.First composition With the second composition also can each self-contained any other composition listed herein, unless specific examples of such components negatively affects microcapsules Performance.The non-limiting example of other compositions includes：It is contained at least one in the first composition and the second composition The non-encapsulated aromatic of at least one in colouring agent, and the second composition.When the first composition comprises to encapsulate aromatic During microcapsules, the first composition also can comprise chemical composition with encapsulating aromatic can be identical or different do not encapsulate aromatic. In some instances, the first composition can be substantially free of selected from propellant, ethanol, detersive surfactant and they The material of combination；Preferably without the material selected from propellant, ethanol, detersive surfactant and combinations thereof.Advance The non-limiting example of agent includes compressed air, nitrogen, inert gas, carbon dioxide, gaseous hydrocarbon such as propane, normal butane, isobutyl Alkene, cyclopropane and their mixture.In some instances, the second composition can be substantially free of selected from propellant, micro-glue The material of capsule, detersive surfactant and combinations thereof；Preferably live without selected from propellant, microcapsules, decontamination surface Property agent and the material of combinations thereof.

According to the expectation of fonnulator, when the second composition comprises volatile solvent and the first composition comprises carrier During with multiple microcapsules, distributor may be configured for distributing 10:1 to 1:10、5:1 to 1:5、3:1 to 1:3、2:1 to 1:2、 Or even 1:1 or 2:Second composition of 1 ratio and the volume ratio of the first composition.Distributor can distribute the second of the first dosage Composition and the first composition of the second dosage so that the first dosage and the second dosage have 30 microlitres to 300 microlitres or 50 Microlitre is to the combined volume of 140 microlitres or 70 microlitres to 110 microlitres.

As it is shown in figure 1, distributor 10 can have shell 20 and actuator 30 and outlet 40.Non-limiting show at some In example, outlet can have the volume of 0.01 cubic millimeter to 0.20 cubic millimeter, such as has 0.03 cubic millimeter in outlet 40 Volume when.In some instances, shell 20 is not required in that；Its non-limiting example is when reservoir is the 50th, 60 by glass When making.When reservoir is made up of glass, two reservoirs can be blow molded by same melten glass, is rendered as having two storages The single bottle of storage.Alternatively, when reservoir is made up of glass, two reservoirs can be blow molded by the melten glass of independent block, It is rendered as two bottles that each there is single reservoir and link together via connector.Those of ordinary skill in the art will Will appreciate that, the multiple of reservoir may design be possible without departing from the teachings of the present invention；Its non-limiting example be Reservoir within reservoir.

As in figure 2 it is shown, distributor 10 also can comprise the first reservoir 50 for storing the first composition 51 and for Store the second reservoir 60 of the second composition 61.The 50th, reservoir 60 can be any shape or design.As in figure 2 it is shown, distributor Can be configured to distribute non-similar volume ratio (non-1:1) the first composition 51 and the second composition 61.First reservoir 50 can There is openend 52 and blind end 53.Second reservoir can have openend 62 and blind end 63.The 52nd, openend 62 can be used in Pump and/or dip tub is made to accommodate in reservoir.Openend the 52nd, 62 also can be used in for reservoir supply composition.In administration Afterwards, openend can be made the 52nd, 62 to add a cover or otherwise seal to prevent from reservoir seepage.In some instances, first Composition 51 can comprise microcapsules 55.Although providing for connecting without gas between reservoir with pump, (its non-limiting example is Layering bottle) alternative device in the case of, dip tub not necessarily, but distributor can include the first dip tub 70 and second Dip tub 80.Distributor can include the first pump 90 (to schematically show) connecting with the first dip tub 70.Distributor also can wrap Include the second pump 100 (to schematically show) connecting with the second dip tub 80.Distributor may be additionally configured to include having difference First pump 90 of displaced volume and the second pump 100.In some non-limiting examples, at least one pump can have the defeated of 70 microlitres Go out, and another pump can have the output of 50 microlitres.

As in figure 2 it is shown, when the first composition distributing non-similar ratio and the second composition, the first reservoir 50 can quilt Being configured to the volume than the second reservoir 60 accommodates less, vice versa.If including dip tub, the then length of the first dip tub 70 Spending also short than the second dip tub 80, vice versa.Unless additionally illustrated in the accompanying drawings, otherwise the inner workings of pump is normal Rule.This type of inner workings has been abridged and has been shown as schematic, in order to without departing substantially from teaching herein content.There are 30 microlitres To the suitable pump of 140 microlitre outputs available from such as Aptargroup Inc., the confession of MeadWeastavo Corp. and Albea Answer business.Some examples of suitable pump are the pre-compression spray pump described in WO2012110744, EP0757592, EP0623060.First Pump 90 can have room 91 and the second pump 100 can have room 101.As in figure 2 it is shown, the first pump 90 and the second pump 100 can be configured Become to make room the 91st, 101 to have different length and similar or identical diameter.When described pump is for fine fragrance, such as this Pump shown in Wen is exaggerated in some cases demonstrating interior details, and size as shown here may present than it Less.

As in figure 2 it is shown, distributor can include first passage 110 and second channel 120.In some non-limiting examples, The 110th, passage 120 has the volume of 5 millimeters to 15 millimeters, and its example is when passage has the volume of 8.4 cubic millimeters.First Passage 110 can have near-end 111 and far-end 112.Second channel 120 can have near-end 121 and far-end 122.First passage 110 Near-end 111 connects with the outlet 92 of the first pump 90.The outlet 102 of the near-end 121 of second channel 120 and the second pump 100 is even Logical.First passage 110 can be shorter compared to the length of second channel 120.Second channel 120 may be disposed at first passage 110 Top (as shown in Figure 2) or the lower section of first passage 110.Alternatively, the first and second passages can substantially coplanar (i.e. parallel type Exist).The 92nd, outlet 102 can have similar or different diameter, and it can provide similar or different volume.In some non-limits In property example processed, outlet has the diameter of 0.05 millimeter to 3 millimeters, and its example has 1.4 millimeters when an outlet When diameter and another outlet have the diameter of 1 millimeter.In some non-limiting examples, the 92nd, outlet 102 can have The volume of 2 cubic millimeters to 10 cubic millimeters, such as an outlet have the volume of 7.70 cubic millimeters and another When outlet has the volume of 3.93 cubic millimeters.

In order to make obstruction minimize, for example, comprise particle (such as microcapsules) at composition or demonstrate and be different from other As being likely to occur during the viscosity of composition, the 110th, passage 120 may be configured such that a passage has and leads to than another The bigger diameter in road.When particle is contained in composition, the passage with larger diameter can be used to prevent from blocking.

The far-end 112 of first passage 110 and the far-end 122 of second channel 120 for being delivered to premixer 150 by composition In.In some instances, premixer 150 can include the internal diversion plate beneficially mixing.Distributor may also comprise at least one Charging, to be delivered to minor air cell 130 mixture of the first and second compositions from premixer 150.Minor air cell 130 can give First composition 51 and the second composition 61 eddy motion.In some instances, as in figure 2 it is shown, distributor can include and eddy current The first charging 270 that room 130 connects with premixer 150.Distributor may also include and connects with minor air cell 130 and premixer 150 Second charging 280.First charging 270 is configured with compared to the second charging 280 different diameters.Alternatively, feed 270th, 280 can have substantially similar diameter.In some instances, distributor can have more than two charging.Minor air cell 130 can Give the first composition 51 and the second composition 61 eddy motion.Minor air cell can be configured to deliver certain spray characteristics.Example As, in minor air cell, the motion of whirlpool or circular motion or other shapes, the spy of motion can be provided for the fluid entering minor air cell Levy and determined by the indoor design of minor air cell 130.In some cases, premixer 150 mixes two kinds of compositions and can reduce group The surface tension of compound, and thus improve the atomization level of liquid.When the surface tension composition different with viscosity is present in storage When in storage, the introducing of minor air cell 130 can promote atomization further.Alternatively, as it is shown on figure 3, distributor 10 can be configured to The similar volume ratio (such as 1 of distribution:1) the first composition 51 and the second composition 61.In some instances, reservoir 50 and 60 Similar size can be.First pump 90 can be selected for delivering similar output with the second pump 100.In some instances, divide Orchestration may be configured such that the 91st, room 101 has similar or identical diameter, has same or like length so that living simultaneously The haul distance of plug is same or like.In some instances, distributor may be configured such that when the length of passage is different, supplies The reservoir of the composition that should comprise microcapsules delivers via longer passage.

Alternatively, as shown in Figure 3A, distributor can be configured to distribute non-similar volume ratio (non-1:1) the first composition 51 and second composition 61.In some instances, the first pump 90 and the second pump 100 may be configured such that the 91st, room 101 has not Same diameter has same or like length simultaneously, so that the haul distance of piston is same or like, but pump output is but Different.This type of constructs can deliver large volume of composition 51 or 61 by the various sizes of piston of permission a series of points Join.

Alternatively, as shown in Figure 3A, distributor can be configured to distribute non-similar ratio (non-1:1) the first composition 51 With the second composition 61.In some instances, the first pump 90 and the second pump 100 may be configured such that the 91st, room 101 has difference Length and similar or identical diameter.This type of construction can by allow different haul distance piston and provide composition 51 or The distribution of a series of large volumes of 61.

Alternatively, as shown in Figure 4, first passage 110 and second channel 120 can be positioned such that passage the 110th, 120 by group Compound is delivered to be positioned at outlet 40 the 92nd, between 102 for the outlet.Additionally, compared with in Fig. 2, the second outlet 102 is oriented to Separating out in the first outlet 92 that mouth 40 is farther to be contrasted, the first outlet 92 and the second outlet 102 can be oriented so that First outlet 92 and the second outlet 102 are of substantially equal with the distance of outlet 40.As shown in Figure 4, first passage 110 and second Passage 120 can be configured to its content delivery to the premixer being positioned between the first outlet 92 and the second outlet 102 150.As shown in Figure 4 A, composition is delivered in premixer 150 via first passage 110 and second channel 120.Once enter pre- Mixed room 150, the mixture of the first and second compositions can advance to minor air cell via the first charging 270 and the second charging 280 In 130.Distributor can include the dividing plate 391 contributing to forming the first charging 270 and the second charging 280.

Fig. 5 illustrates the D profile that distributor constructs, and wherein first passage 110 and second channel 120 are positioned such that The 110th, passage 120 delivers the composition to be positioned at outlet 40 the 92nd, between 102 for the outlet, and this is similar with the distributor of Fig. 4.Figure 5A shows that the construction shown in Fig. 5 does not shows minor air cell 130, enabling preferably display channel the 270th, 280 and dividing plate 391.

Fig. 5 B illustrates the D profile of the non-limiting example of the minor air cell 130 that can include in distributor described herein. It may be noted that the actual design of minor air cell can change, and those of ordinary skill in the art it will be recognized that minor air cell design Multiple modification are possible.Minor air cell can be used to give composition vortex movement, and described vortex movement promotes the group of atomization Compound is delivered in external environment condition via outlet 40.

Seeing Fig. 5 B, minor air cell 130 can have the wall 390 forming cylindrical shape.Minor air cell 130 can include contributing to being formed One or more deflectors 380 of flow channel 355.Deflector is designed to form one or more flow channel 355, Described flow channel is used for its content delivery to vortex 371.In some instances, minor air cell 130 can have at least two Individual flow channel, at least three flow channel or be more than four flow channels.Outlet 40 is used for fluid from vortex 371 row It is put in the external environment condition of distributor.In some non-limiting examples, the combined volume of vortex 371 and flow channel can be 0.10 cubic millimeter to 1.0 cubic millimeters, such as when combined volume is 0.21 cubic millimeter.

As shown in Figure 6, distributor may be configured such that in some instances and is being delivered to composition in premixer 150 Before, first passage 110 and second channel 120 formed one another around concentric structure 290.As shown in Figure 6A, concentric structure 290 Can include：Comprise the inner concentric passage 292 of the content delivering via first passage 110, and deliver the interior of second channel 120 The tolerant outer concentric passage 294 around inner concentric passage 292.As shown in Figure 6B, composition is via inner concentric passage 292 and outer concentric passage 294 be delivered in premixer 150.Once enter premixer 150, mixing of the first and second compositions Compound just advances in minor air cell 130 via the first charging 270 and the second charging 280.Distributor can include contributing to forming One charging 270 and the dividing plate 391 of the second charging 280.Once entering minor air cell 130, the mixture of the first and second compositions is just It is discharged in external environment condition via outlet 40.

As shown in Figure 7, it may include for rinse assembly 399 rinse the 150th, minor air cell 130 of premixer and outlet 40, from And prevent can by the obstruction caused by the remaining microcapsules staying after each actuation events, or otherwise promote satisfied and Seamless actuating is experienced.Additionally, when the first composition distributing different ratio and the second composition, assembly 399 can be used.Group Part 399 can include actuator the 30th, the first pump the 90th, the second pump the 100th, first piston 430 and the second piston 440.First pump 90 He Second pump 100 can have the spring 421 being urged upwardly with against piston.First pump 90 can have bigger than the second pump 100 Output.

In some instances, as it is shown in fig. 7, the assembly 399 for rinsing can be configured to include external compensation piece 450 He The assembly 410 of slip joint 460.External compensation piece 450 can be made up of flexibility/compressible/elastomeric material and can be such as figure institute The spring showing.See assembly 410, need the power of mobile piston 440 less than the power needing to compress external compensation piece 450.When second When piston 440 reaches its final position, external compensation piece compensates the relatively short distance that first piston 430 is advanced, the simultaneously company of slip Fitting 460 provides the housing of the near-end 570 of the piston rod 558 being able to receive that the second piston 440, so that actuator 30 can continue Seamlessly advance.Second piston 440 also has head 530 at the far-end 575s of piston rod 558.Therefore, from the first pump 90 and The composition of two pump 100 pumpings is distributed simultaneously, only pumps composition from the first pump 90 afterwards.This type of design will use the first pump The composition of the volume V1 of 90 pumpings rinses the 150th, minor air cell 130 of premixer and outlet 40.In this type of construction, actuator 30 will Continue to move with smooth motion, make the 130th, premixer 150 of minor air cell and outlet 40 to be rinsed simultaneously, thus be user Seamless actuating is provided to experience.It will thus be appreciated that can be such as by changing the stroke of first piston 430 and the second piston 440 Length and/or the diameter by regulation pump regulate volume V1.

Seeing Fig. 8, assembly 410 can be included within distributor 10.In some instances, the second piston of the second pump 100 440 connect with external compensation piece 450.Assembly 410 can include the slip joint of the piston rod 558 for accepting the second piston 440 460 (being shown as void space), thus compensate the travel distance difference between first piston 430 and the second piston 440.

As shown in Figure 8, distributor 10 can be at primary importance 403, and wherein first piston 430 and the second piston 440 are in Its initial position, and external compensation piece 450 is in relaxed state.As shown in Figure 8 A, distributor 10 can be at the second place 404, this second place is by user caused by actuator 30 applies power, and wherein first piston 430 and the second piston 440 are all works Make, which results in the first composition 51 and the second composition 61 is pumped in the 150th, minor air cell 130 of premixer and outlet 40, with When external compensation piece 450 still in relaxed state.As shown in Figure 8 B, distributor 10 can be at the 3rd position 405, the 3rd position Being continued caused by actuator 30 applies power by user, wherein first piston 430 is work and the second piston 440 is in quiet Only state, this causes the second composition 61 to continue pumping and the first composition 51 stops being pumped into the 150th, minor air cell of premixer 130 and outlet 40 in.As shown in Figure 8 C, distributor 10 can be at the 4th position 406, and the 4th position is continued to cause by user Caused by dynamic device 30 applies power, wherein first piston 430 is in its inactive state, and the second piston 440 is still in inactive state, outside Compensating plate 450 is in compressive state, and the near-end 570 of the piston rod 558 of the second piston 440 is positioned within slip joint 460. 4th position causes the second composition 61 to stop being pumped in the 130th, premixer 150 of minor air cell and outlet 40.

These positions cause the flowing in two stages of composition.In the first phase, composition flows to premixer 150 Until distributor 10 enters the 3rd position, this premixer includes by the first composition 51 of simultaneous pumping and the second composition 61. Entering the flowing causing second stage in the 3rd position, external compensation piece 450 is compressed at this point, makes the second piston 440 Being partly in slip joint 460 of piston rod 558, first piston 430 continues on simultaneously；Thus cause premixer the 150th, Minor air cell 130 and outlet 40 are rinsed by the second composition 61, and the overall seamless actuating of user is experienced.

Alternatively as it is shown in figure 9, assembly 399 for rinsing can be configured to include juxtaposition at the of the second piston 440 The assembly 411 of the internal compensation piece 550 between one head 545 and the second head 555, thus help compensate for the second piston 440 Travel distance shorter compared with first piston 430.Internal compensation piece 550 can be made up of flexibility/compressible/elastomeric material and It can be spring as depicted.Second piston can include piston rod 558, near at piston rod 558 of this piston rod and actuator 30 Hold operation association at 570.Second piston also at the far-end 575s of piston rod 558 with the first head the 545th, the second head the 555th, with And internal compensation piece 550 operation association.First head 545 of the second piston 440 may also include hole 562 and (illustrates and have along hole The piston rod 558 of inner side), described hole makes piston rod 558 can pass through the first head 545 of the second piston 440 and enter position In space 560 in the second pump 100.When the first head 545 reaches stopper element 564, space 560 can primary recipient piston Bar 558.Piston rod 558 may also include for making the first head the 545th, internal compensation piece 550 and the second head 555 engage at least One flange 559, so that the power that described parts are provided by spring 421 is back to initial position from final position.

See assembly 411, make the second piston 440 move required power less than the power compressed needed for internal compensation piece 550.Group Part 411 provides a series of stream, is wherein activating period the first composition and the second composition by simultaneous pumping until second lives First head 545 of plug 440 reaches its final position, and internal compensation piece 550 is compressed at this point, makes the second head 555 more Near the first head 545.The composition of the volume V1 using the first pump 90 to pump is rinsed premixer's the 150th, eddy current by this type of design Room 130 and outlet 40.In this type of construction, although the 150th, minor air cell 130 of premixer and outlet 40 are rinsed, actuator 30 will Continue to move with smooth motion.

Seeing Figure 10, assembly 411 can be included within distributor 10.In this type of construction, operation actuator 30 will cause First piston 430 and the second piston 440 move so that the first composition 51 and the second composition 61 are by simultaneous pumping, until One head 545 reaches its final position, and internal compensation piece 550 is compressed at this point, makes the first head 545 and the second head 555 compared to original position closer to.When the first head 545 and the second head 555 closer to when, then the second composition 61 will rinse the 150th, minor air cell 130 of premixer and outlet 40, and other parts including are until first piston 535 reaches it Final position is put.

When for distributor, assembly 411 can provide the flowing in two stages for two kinds of compositions.As shown in Figure 10, divide Orchestration 10 can be at primary importance 403, and wherein first piston 430 and the second piston 440 are in its initial position, and internal benefit Repay piece 550 and be in relaxed state, be pumped to the 150th, minor air cell 130 of premixer and outlet 40 without a kind of composition.Such as figure Shown in 10A, distributor 10 can be at the second place 404, this second place by user caused by actuator 30 applies power, wherein First piston 430 and the second piston 440 are all work, which results in the first composition 51 and the second composition 61 is pumped into pre- In mixed the 150th, minor air cell 130, room and outlet 40, internal compensation piece 550 is still in relaxed state simultaneously.As shown in Figure 10 B, distribute Device 10 can be at the 3rd position 405, and the 3rd position 405 is continued caused by actuator 30 applies power by user, and wherein first Piston 430 is work and the second piston 440 remains static, and this causes the second composition 61 to continue pumping and first Composition 51 stops being pumped in the 150th, minor air cell 130 of premixer and outlet 40.As illustrated in figure 10 c, distributor 10 can be at Four positions 406, the 4th position 406 is by user's continuation caused by actuator 30 applies power, and wherein first piston 430 is in it Inactive state, the second piston 440 is still in inactive state, and internal compensation piece 550 is in compressive state, and the second piston 440 The part of piston rod 558 be positioned within the space 560 of the second pump 100.4th position 406 causes the second composition 61 to stop Only pump and the first composition 51 continues stopping and being pumped in the 150th, minor air cell 130 of premixer and outlet 40.

These positions cause the flowing in two stages of composition.In the first phase, composition flows to premixer 150 Until distributor 10 enters the 3rd position 405, this premixer includes by simultaneous pumping to premixer the 150th, minor air cell 130 and outlet The first composition 51 in 40 and the second composition 61.Enter the flowing causing second stage in the 3rd position 405, at this point Internal compensation piece 550 will be compressed, make the first head 545 and the second head 555 closer to and make piston rod 558 enter space In 560, thus pump the second composition 61 until first piston 430 reaches its final position, and rush with the second composition 61 Wash the 150th, minor air cell 130 of premixer and outlet 40.

As shown in figure 11, the assembly 399 for rinsing can be configured to include the group of pivotal point 610 and pivot hinge 620 Part 412.When the length of piston is different, pivotal point 610 and pivot hinge 620 compensate first piston 430 and the second piston 440 row The range difference entering.Actuator 30 also can operate with first piston 430 and the second piston 440 and associate.First piston 430 and the first pump 90 connect, and the second piston 440 connects with the second pump 100.In some instances, pivotal point 610 is positioned at the one of actuator 30 Hold, and pivot hinge 620 is positioned on the actuator 30 between first piston 430 and the second piston 440.Assembly 412 makes to cause Dynamic device 30 can move with continuous print smooth motion, causes the 150th, minor air cell 130 of premixer and outlet 40 by the second composition 61 Rinse.In some instances, distributor may be designed such that pivot on the shell of the housing at encapsulating actuator for the pivotal point 610 Turn.In some instances, pivotal point 610 is by the ball-and-socket of each end or the shell being connected to housing by the connecting rod forming hinge.

When user does not operates actuator 30, assembly 412 can have primary importance 403.Primary importance 403 is to second The transformation putting 404 causes first piston 430 and the second piston 440 to be advanced within the first pump 90 and the second pump 100 respectively.When When one piston 430 and the second piston 440 are advanced in the first pump 90 and the second pump 100, the first pump 90 and the second pump 100 are all raw Producing property.

As shown in Figure 11 A, the power 670 applying further may result in the second place 404, wherein said actuator 30 compared to Actuator in primary importance 403 is to tilt.The existence of pivotal point 610 and pivot hinge 620 makes the second piston 440 Two pumps 100 continue on, makes first piston 430 be maintained at its initial position simultaneously.For making assembly 412 enter the second place 405 and operate actuator 30 make second composition 61 of volume V1 can rinse the 150th, minor air cell 130 of premixer and outlet 40, Because the second pump 100 is still for productive and the first pump 90 is nonproductive.As shown in Figure 11 B, the power 670 that user applies The 3rd position 405 is changed in the position that can make device 412 so that the second piston 440 now reaches it the most in the second pump 100 Final position is put.At 405s, position, the first pump 90 and the second pump 100 are all nonproductive.

As shown in figure 12, the assembly 399 for rinsing can be configured to include to have the first end 750 and the second end 760 The assembly 413 of first piston 430, wherein the first end 750 of first piston 430 includes that head 530 (not shown) and first is lived Second end 760 of plug associates with outside leaf spring 770 operation.Outside leaf spring 770 is for compensating the distance advanced with the second piston 440 Compare the shorter distance that first piston 430 is advanced.Second piston 440 connects with the second pump 100.Actuator 30 can be around pivot The axis of point 610 offer rotates.Alternatively, for example by assembling compressible outside leaf spring 770, assembly 413 can be configured to It is not included or uses pivotal point 610.Outside leaf spring 770 can be positioned so that and connects with the second pump 100.Figure 12 A illustrates group The side view of part 413.As shown in figure 13, assembly 413 can be included in distributor 10.Figure 13 A illustrates assembly 413 at distributor 10 The side view of section when middle.Figure 13 B illustrates the 150th, minor air cell 130 of premixer and outlet 40 structure relative to outside leaf spring 770 Make.

Assembly 413 is attached in distributor 10 cause the flowing in two stages of composition.Figure 13 C illustrates distributor 10 In assembly 413, wherein distributor is in primary importance 403.At primary importance 403s, first piston 430 and the second piston 440 are in its initial position.During the first stage, the first composition 51 and the second composition 61 the 150th, the minor air cell to premixer 130 and outlet 40 flowing because the first composition 51 and the second composition 61 by simultaneous pumping until first piston 430 reaches it Final position.First stage is characterised by that distributor is converted to the second place 404 from primary importance 403.As illustrated in figure 13d, After first piston 430 enters its final position, the first pump 90 will no longer work, until the first and second pistons are back to it Initial position (sees primary importance 403).Will be to actuator 30 if continued after first piston 430 reaches its initial position Applying power, then continuation will be applied power to the second piston 440 by actuator 30 so that the second piston continues row in the second pump 100 Enter.Second stage is characterised by that distributor is converted to the 3rd position 405 from the second place 404.In this regard, such as figure Shown in 13E, continuation is operated by the second pump 100 until the second piston 440 reaches its final position.Outside leaf spring 770 can be joined It is set to rotate about the axis thereof (if including pivotal point 610) or compressed (if not including pivotal point 610), thus By making the second pump 100 be productibility and the first pump 90 is no longer productive and allow seamless actuating to experience.

In some instances, distributor may be designed such that the shell of the housing at encapsulating actuator for the pivotal point 610 Upper pivot.In some instances, pivotal point 610 is connected to the shell of housing by the ball-and-socket of each end.In some instances, such as Figure 14 With shown in Figure 14 A, pivotal point 610 is connected to shell by the connecting rod forming hinge.

Therefore, outside leaf spring 770 as shown in Figure 13 and Figure 13 A-13F for the use causes the stream in two stages of composition Dynamic.In the first phase, composition the 150th, minor air cell 130 and outlet 40 flowing to premixer, until first piston 430 reaches it Final position.During the flowing of second stage, outside leaf spring 770 makes first piston 430 maintain at its final position, and And the second piston 440 is continued in the second pump 100, cause the 150th, minor air cell 130 of premixer and outlet 40 by volume Second composition 61 of V1 rinses.

Alternatively, distributor can be customized to by minor air cell first blend compositions and face leave before make two Plant composition first to mix.As shown in figure 15, distributor 10 can comprise the first reservoir 50 for storing the first composition 51 And for storing the second reservoir 60 of the second composition 61.The 50th, reservoir 60 can be any shape or design.Such as Figure 15 institute Showing, distributor can be configured to distribute similar volume ratio (such as 1:1) the first composition 51 and the second composition 61 or can It is configured to distribute non-similar volume ratio.First reservoir 50 can have openend 52 and blind end 53.Second reservoir can There is openend 62 and blind end 63.The 52nd, openend 62 can be used in making pump and/or dip tub accommodate in reservoir.Opening End the 52nd, 62 also can be used in for reservoir supply composition.After administration, openend can be made the 52nd, 62 to add a cover or with its other party Formula seals to prevent from reservoir seepage.In some instances, the first composition 51 can comprise microcapsules 55.Although using providing In the case of connecting the alternative device of (its non-limiting example is layering bottle) between reservoir with pump without gas, dip tub is not Necessary, but distributor can include the first dip tub 70 and the second dip tub 80.Distributor can include and the first dip tub 70 First pump 90 (to schematically show) of connection.Distributor may also include the second pump 100 connecting with the second dip tub 80 (to show Meaning property illustrates).Unless additionally illustrated in the accompanying drawings, otherwise the inner workings of pump is conventional.This type of inner workings Abridge and be shown as schematic, in order to not obscured the details of present teachings.There is the suitable of 30 microlitres to 140 microlitre outputs Suitable pump is available from such as Aptargroup Inc., the supplier of MeadWeastavo Corp. and Albea.Some of suitable pump Example is the pre-compression spray pump described in WO2012110744, EP0757592, EP0623060.First pump 90 can have room 91 and Second pump 100 can have room 101.When described pump is for fine fragrance, pump as illustrated herein is put in some cases Greatly demonstrating interior details, and size may than its as shown here present less.

Distributor can include first passage 110 and second channel 120.In some non-limiting examples, passage the 110th, 120 Having the volume of 5 millimeters to 15 millimeters, its example is when passage has the volume of 8.4 cubic millimeters.First passage 110 can have Have near-end 111 and far-end 112.Second channel 120 can have near-end 121 and far-end 122.The near-end 111 of first passage 110 and The outlet 92 of one pump 90 connects.The near-end 121 of second channel 120 connects with the outlet 102 of the second pump 100.First passage 110 can be shorter compared to the length of second channel 120.Second channel 120 may be disposed at the top of first passage 110 (such as Fig. 3 institute Show) or the lower section of first passage 110.Alternatively, first passage and second channel can substantially coplanar (i.e. parallel type existence).Go out The 92nd, mouthful pipe 102 can have similar or different diameter, and it can provide similar or different volume.In some non-limiting examples In, outlet has the diameter of 0.05 millimeter to 3 millimeters, its example be when outlet have 1.4 millimeters diameter and When another outlet has the diameter of 1 millimeter.In some non-limiting examples, the 92nd, outlet 102 can have 2 cubes of millis The volume of rice to 10 cubic millimeters, such as has volume and another outlet tool of 7.70 cubic millimeters at an outlet When having the volume of 3.93 cubic millimeters.

The far-end 112 of first passage 110 and the far-end 122 of second channel 120 for being delivered to minor air cell 130 by composition In.Minor air cell 130 can give the first composition 51 and the second composition 61 eddy motion.Minor air cell can be configured to deliver necessarily Spray characteristics.For example, in minor air cell, whirlpool or circular motion or other shapes can be provided for the fluid entering minor air cell Motion, motion characteristics are determined by the indoor design of minor air cell 130.When the composition of surface tension and viscosity B coefficent is present in storage When in storage, the introducing of minor air cell 130 can provide enough atomizations.In some cases, minor air cell mixes two kinds of combinations Thing can reduce the surface tension of composition, and thus improves the atomization level of liquid.

As shown in fig. 15, first passage 110 can have the first diameter 250 and second channel 120 can have Second bobbin diameter 260 so that the first diameter 250 and Second bobbin diameter 260 are same or about.Minor air cell 130 can include with first passage 110 even The first logical charging 270 and the second charging 280 connecting with second channel 120.First charging 270 be configured with Second charging 280 roughly the same diameters.Alternatively, the first charging 270 and the second charging 280 can have different diameters.Separately Selection of land, charging the 270th, 280 diameter can be similar to or identical.Alternatively, more than one charging can be with each channel connection.Alternative Ground, more than one charging can be with each channel connection, and each passage can have not become compared to number for other passages The charging of ratio.In order to make obstruction minimize, for example, comprise particle (such as microcapsules) or demonstrate at composition and be different from As being likely to occur during the viscosity of other compositions, the 110th, passage 120 may be configured such that a passage has than another The bigger diameter of individual passage.

As shown in figure 16, first passage 110 and second channel 120 can be configured to its content delivery to being positioned at first Minor air cell 130 between outlet 92 and the second outlet 102.In some instances, as shown in figure 16, first passage 110 He Second channel 120 can be positioned such that the 110th, passage 120 delivers the composition to be positioned at outlet 40 the 92nd, between 102 for the outlet. First outlet 92 and the second outlet 102 can be oriented so that the first outlet 92 and the second outlet 102 and minor air cell The distance of 130 is of substantially equal.Figure 16 A illustrates the section with the distributor constructing as shown in figure 16, wherein the first outlet 92 And second outlet 102 the 51st, composition 61 is delivered to the outlet being positioned between outlet.

As shown in figure 17, distributor may be configured such that in some instances and composition be delivered to minor air cell 130 Before in, first passage 110 and second channel 120 formed one another around concentric structure 290.As shown in Figure 17 A, concentric structure 290 can include inner concentric passage 292 and the outer concentric passage 294 around inner concentric passage 292.As seen in this fig. 17b, same Heart construction 290 may be configured such that first passage 110 and the first charging 270 fluid connections, and this first charging 270 is by content It is delivered to minor air cell 130 from first passage 110.Concentric structure 290 may also be configured such that second channel 120 and the second charging 280 fluid connections, content is delivered to minor air cell 130 from second channel 120 by this second charging 280.

Figure 18-18C illustrates the eddy current can being included in distributor when first composition occurs mixing in minor air cell 130 The non-limiting example of room 130.It may be noted that the actual design of minor air cell can change, and those of ordinary skill in the art It will be recognized that multiple modification of minor air cell's design are possible.In some instances, minor air cell can also be designed such that first The content of reservoir and the second reservoir mixes before external environment condition facing to exit in minor air cell.Additionally, minor air cell Can be used to give composition vortex movement, described vortex movement promotes the atomization of composition for via outlet 40 delivery In external environment condition.

Seeing Figure 18, minor air cell 130 can have the wall 390 forming cylindrical shape.Minor air cell 130 can include the first deflector 381, the second deflector 384, the 3rd deflector 386 and the 4th deflector 388, it is logical that these deflectors contribute to forming flowing together Road.Deflector can be designed to form the first flow channel the 356th, second flow path the 360th, the 3rd flow channel 365 and Four flow channels 370, described flow channel is for by its content delivery to mixed zone 371, and described mixed zone is for will Mixed before outlet 40 is left.In some instances, minor air cell 130 can have at least two flow channel, at least Three flow channels or be more than four flow channels.In some non-limiting examples, the group of mixed zone 371 and flow channel Fit amassing can be 0.10 cubic millimeter to 1.0 cubic millimeters, such as when combined volume is 0.21 cubic millimeter.With reference to Figure 18 A, Minor air cell 130 can include the dividing plate 391 forming swirl channel 393 in swirl channel 392 and second in first, and this dividing plate is used for making Two kinds of compositions were held apart at before being delivered to mixed zone 371.In some non-limiting examples, in first swirl channel and In second, the combined volume of swirl channel can be 0.05 cubic millimeter to 3.0 cubic millimeters, such as combined volume be 1.10 stand During square millimeter.In first, swirl channel 392 can be by its Content to the first flow channel 356 and second flow path 360 In.In second, swirl channel 393 can be by its Content to the 3rd flow channel 365 and the 4th flow channel 370.Such as figure Shown in 18B, outlet 40 for being discharged into the external environment condition of distributor fluid from mixed zone 371.

Seeing Figure 19, assembly 410 can include within distributor 10, and wherein first composition mixes in minor air cell 130. Distributor can include the minor air cell 130 that actuator 30 connects with first passage 110 and second channel 120.First passage 110 is also Connect with the first outlet 92, and second channel 120 also connects with the second outlet 102.Second piston of the second pump 100 440 associate with external compensation piece 450 operation.Assembly 410 can include the slip of the piston rod 558 for receiving the second piston 440 Connector 460 (being shown as void space), thus compensate the travel distance difference between first piston 430 and the second piston 440.When with When distributor 10, assembly 410 can allow minor air cell 130 and the flushing of outlet 40.

Seeing Figure 20, assembly 411 can include within distributor 10, and wherein first composition mixes in minor air cell 130. As shown in figure 20, distributor 10 can include the minor air cell 130 that actuator 30 connects with first passage 110 and second channel 120. First passage 110 also connects with the first outlet 92, and second channel 120 also connects with the second outlet 102.At this type of structure In making, operation actuator 30 will cause first piston 430 and the second piston 440 to move so that the first composition 51 and second group Compound 61 is by simultaneous pumping, until the first head 545 reaches its final position, internal compensation piece 550 is compressed at this point, makes First head 545 and the second head 555 compared to original position closer to.When the first head 545 and the second head 555 more When close, then the second composition 61 by flushing minor air cell 130 and exports 40 until first piston 535 reaches its final position.

As shown in figure 21, the assembly 399 for rinsing can be configured to include the group of pivotal point 610 and pivot hinge 620 Part 412, and it is used for the distributor of first blend compositions in minor air cell 130.When the haul distance of piston is different, pivot Point 610 and pivot hinge 620 compensate first piston 430 and the range difference of the second piston 440 traveling.Actuator 30 also can be with first Piston 430 associates with the second piston 440 operation.First piston 430 connects with the first pump 90, and the second piston 440 and second Pump 100 connects.In some instances, pivotal point 610 is positioned at one end of actuator 30, and pivot hinge 620 is positioned at first and lives On actuator 30 between plug 430 and the second piston 440.Assembly 412 makes actuator 30 can come with continuous print smooth motion Motion, causes minor air cell 130 and outlet 40 to be rinsed by the second composition 61.In some instances, distributor is designed to make The shell obtaining the housing with encapsulating actuator for the pivotal point 610 is connected and pivots on it.In some instances, pivotal point 610 Can be by the ball-and-socket of each end or the shell being connected to housing by the connecting rod forming hinge.

As shown in figure 22, the assembly 399 for rinsing can be configured to include to have the first end 750 and the second end 760 The assembly 413 of first piston 430, wherein the first end 750 of first piston 430 connect with the first pump 90 and first piston Two ends 760 associate with outside leaf spring 770 operation.Assembly 413 can be used for distributor, and wherein composition is first in minor air cell 130 Mixing.Outside leaf spring 770 for compensate that first piston 430 compared with the distance that the second piston 440 is advanced advanced shorter away from From.Second piston 440 connects with the second pump 100.Actuator 30 can rotate around the axis that pivotal point 610 provides.Alternatively, group Part 413 may be configured such that it does not includes or utilizes pivotal point 610.Outside leaf spring 770 can be positioned so that with the second pump 100 even Logical.

In some instances, distributor can introduce the assembly for flushing being used together with the composition not described in detail herein 399 (when such composition is incompatible and needs to be stored in independent reservoir).Therefore, the assembly 399 for rinsing can For not heretofore described particle or be used for other compositions, its non-limiting example is peroxide/oxidative coloration of hair agent, Wherein provided by peroxide and rinse.

It should be appreciated that small improvement for example for preventing the valve of reverse flow from including among this paper without departing from this Bright.Non-limiting example is for including valve to prevent from minor air cell's adverse current to passage.Other nonrestrictive small improvement can be wrapped Purse rope piece enters pump to prevent agglomerated particle.

When distributor is for fine fragrance application, distributor should be configured to distribution the first He under abundant atomization The mixture of the second composition.Some non-limiting examples of the variable that can affect size distribution are the first and second compositions The intrinsic design of mixability, the content of composition itself, and distributor.Size distribution can by use equipped with swash The particle size analyzer of light diffraction techniques, such as purchased from those of Malvern Instruments (UK).

Table 1 below is shown in the appropriate particle size distribution providing the fully distributor of atomization used in fine fragrance application Non-limiting example.Should be noted for this specific distributor and composition, De Brouckere Mean Diameter (i.e. volume Or moment of mass is average) (i.e. D [4] [3]) are 98.92 microns, and Satuer Mean Diameter (i.e. surface product moment is average) (i.e. D [3,2]) are 55.42 microns and (see entitled " the Basic Principles of Particle of Dr.Alan Rawle The technical papers of Size Analysis ", describes how to calculate De Brouckere Mean Diameter and Sauter Mean Diameter).

Table 1 below illustrates granularity suitable for providing the distributor of the abundant atomization of conventional fine perfume composition Distribution.

Table 1

Granularity (μm)	%V ＜	%V	Granularity (μm)	%V ＜	%V	Granularity (μm)	%V ＜	%V
									0.117	0.00	0.00	2.51	0.00	0.00	54.12	37.33	10.54
0.136	0.00	0.00	2.93	0.00	0.00	63.10	48.70	11.37
									0.158	0.00	0.00	3.41	0.00	0.00	73.56	59.96	11.26
0.185	0.00	0.00	3.98	0.00	0.00	85.77	70.20	10.23
									0.215	0.00	0.00	4.64	0.00	0.00	100.00	78.71	8.51
0.251	0.00	0.00	5.41	0.00	0.00	116.59	85.13	6.43
									0.293	0.00	0.00	6.31	0.00	0.00	135.94	89.48	4.35
0.341	0.00	0.00	7.36	0.00	0.00	158.49	92.06	2.58
									0.398	0.00	0.00	8.58	0.00	0.00	184.79	93.35	1.28
0.464	0.00	0.00	10.00	1.26	1.26	215.44	93.85	0.50
									0.541	0.00	0.00	11.66	1.26	0.00	251.19	94.00	0.16
0.631	0.00	0.00	13.59	1.26	0.00	292.87	94.13	0.13
									0.736	0.00	0.00	15.85	1.26	0.00	341.46	94.42	0.30
0.858	0.00	0.00	18.48	1.28	0.03	398.11	94.99	0.56
									1.00	0.00	0.00	21.54	1.80	0.52	464.16	95.82	0.83
1.17	0.00	0.00	25.12	3.27	1.47	541.17	96.84	1.02
									1.36	0.00	0.00	29.29	6.18	2.91	630.96	97.91	1.08
1.58	0.00	0.00	34.15	10.96	4.78	735.64	98.89	0.97
									1.85	0.00	0.00	39.81	17.86	6.90	857.70	99.62	0.73
2.15	0.00	0.00	46.42	26.80	8.94	1000.00	100.00	0.38

Comprise water and microcapsules 55 when the distributor 10 including premixer 150 and minor air cell 130 as described herein sprays The first composition 51 and when comprising the second composition 51 of volatile solvent, following size distribution is possible.For this type of Distributor and the combination of composition, De Brouckere Mean Diameter is 91.49 microns and Satuer Mean Diameter is 71.08 microns.Table 2 below illustrates when distributor 10 includes premixer 150 and minor air cell 130 and for spraying bag First composition 51 of aqueous and microcapsules 55 and when comprising the second composition 51 of volatile solvent, in fine fragrance application In the used appropriate particle size distribution that the fully distributor of atomization is provided.

Table 2

Granularity (μm)	%V ＜	%V	Granularity (μm)	%V ＜	%V	Granularity (μm)	%V ＜	%V
									0.117	0.00	0.00	2.51	0.00	0.00	54.12	20.30	9.56
0.136	0.00	0.00	2.93	0.00	0.00	63.10	33.01	12.72
									0.158	0.00	0.00	3.41	0.00	0.00	73.56	47.67	14.66
0.185	0.00	0.00	3.98	0.00	0.00	85.77	62.43	14.75
									0.215	0.00	0.00	4.64	0.00	0.00	100.00	75.38	12.95
0.251	0.00	0.00	5.41	0.00	0.00	116.59	85.23	9.86
									0.293	0.00	0.00	6.31	0.00	0.00	135.94	91.62	6.39
0.341	0.00	0.00	7.36	0.00	0.00	158.49	95.03	3.40
									0.398	0.00	0.00	8.58	000	0.00	184.79	96.40	1.38
0.464	0.00	0.00	10.00	0.00	0.00	215.44	96.73	0.33
									0.541	0.00	0.00	11.66	0.00	0.00	251.19	96.73	0.00
0.631	0.00	0.00	13.59	0.00	0.00	292.87	96.73	0.00
									0.736	0.00	0.00	15.85	0.00	0.00	341.46	96.73	0.00
0.858	0.00	0.00	18.48	0.00	0.00	398.11	96.73	0.00
									1.00	0.00	0.00	21.54	0.00	0.00	464.16	99.20	2.47
1.17	0.00	0.00	25.12	0.00	0.00	541.17	100.00	0.80
									1.36	0.00	0.00	29.29	0.24	0.24	630.96	100.00	0.00
1.58	0.00	0.00	34.15	1.46	1.22	735.64	100.00	0.00
									1.85	0.00	0.00	39.81	4.64	3.18	857.70	100.00	0.00
2.15	0.00	0.00	46.42	10.74	6.10	1000.00	100.00	0.00

Composition

Volatile solvent

Composition described herein can comprise the mixture of volatile solvent or volatile solvent.Volatile solvent can account for by institute State composition more than 10 weight %, be more than 30 weight %, more than 40 weight %, more than 50 weight %, more than 60 weight %, big In 70 weight % or more than 90 weight %.The volatile solvent that can be used for this paper can odorlessness and at human body skin relatively It is safe for using on skin.Suitable volatile solvent can include C₁-C₄Alcohol and their mixture.The one of volatile solvent A little non-limiting examples include ethanol, methyl alcohol, propyl alcohol, isopropanol, butanol and their mixture.In some instances, group Compound can comprise the ethanol of by weight of the composition 0.01% to 98%.

Non-volatile solvents

Composition can comprise the mixture of non-volatile solvents or non-volatile solvents.Non-volatile solvents non-limiting Example includes Ergol, diethyl phthalate, isopropyl myristate, propane diols, dipropylene glycol, lemon triethylenetetraminehexaacetic acid Ester and their mixture.

Aromatic

Composition can comprise aromatic.As used herein, " aromatic " is used for indicating and any distribute fragrance materials or comprise The combination of at least one composition distributing fragrance materials.Cosmetically acceptable any aromatic can be used for composition.For example, Aromatic can be the at room temperature aromatic in liquid or solid.In general, the aromatic of one or more non-capsules encapsulating Can based on the weight of composition about 0.001% to about the 40%th, about 0.1% to about the 25%th, about 0.25% to about 20% or about The content of 0.5% to about 15% exists.As described herein and defined, some aromatic can be considered volatile, and its Its aromatic can be considered nonvolatile.

Various different chemicals are known as aromatic, and its non-limiting example includes alcohol, aldehyde, ketone, ether, Schiff Alkali, nitrile and ester.More generally, it is known that comprise various chemical constituent compound mixture naturally occurring plant and animal oil with And exudate is used as aromatic.The non-limiting example of the aromatic that can be used for this paper includes front aromatic, before such as acetal Aromatic and their mixture before aromatic before aromatic before aromatic, ketal, ester, hydrolyzable inorganic-organic.Fragrance If agent can discharge in drying method aromatic in the past.For example, aromatic can be released as the result of simple hydrolysis, or by putting down Movement in weighing apparatus reaction, or changed by pH-, or pass through enzyme r e lease.The aromatic of this paper can phase in their chemical composition To simply, comprise single chemicals and or can comprise the compound mixture of the natural of high complexity and synthetic chemical components, all of It is all selected to provide any desired smell.

Described aromatic can have about 500 DEG C or lower, about 400 DEG C or lower, or about 350 DEG C or lower boiling point (BP).The BP of many aromatic is disclosed in Perfume and Flavor Chemicals (Aroma Chemicals), Steffen Arctander(1969).The ClogP value of independent fragrance material can be about-0.5 or bigger.As used herein, " ClogP " represents the logarithm of the Octanol/water Partition Coefficients with 10 as the end.ClogP can be easy to by program (its being referred to as " CLOGP " Purchased from Daylight Chemical Information Systems Inc., Irvine Calif., USA) calculate, or use Advanced Chemistry Development (ACD/Labs) software V11.02 Meter Calculate.Octanol/water Partition Coefficients is described in more detail in United States Patent (USP) 5,578,563.

The example of suitable aldehyde includes but is not limited to：The positive nonyl of jasminal, anisic aldehyde, capraldehyde, lauryl aldehyde, methyl Ethylhexanal, methyl octyl acetaldehyde, aldehyde C-9, benzaldehyde, neral, geranial, 2,6-octadiene, 1,1-diethoxy-3,7-two Methyl-4-propylbenzyl aldehyde, 2,4-dimethyl-3-cyclohexene-1-formaldehyde, Alpha-Methyl p-isopropyl dihydro cinnamon aldehyde, 3-(3- Isopropyl phenyl) butyraldehyde, jasmonal H, 7-hydroxyl-3,7-dimethyl-octa-1-aldehyde, 2,4-dimethyl-3-cyclohexene-1- Formaldehyde, octanal, phenylacetaldehyde, 2,4-dimethyl-3-cyclohexene-1-formaldehyde, hexanal, 3,7-dimethyl octanal, 6,6-dimethyl are double Ring [3.1.1] hept-2-ene"-2-butyraldehyde, aldehyde C-9, octanal, 2-nonenyl aldehyde, undecylene aldehyde, 2-methyl-4-(2,6,6-trimethyl-1- Cyclohexene-1-base)-2-crotonaldehyde, 2,6-dimethyl octanal, 3-(p-isopropyl phenyl) propionic aldehyde, 3-phenyl-4-pentenals, perfume (or spice) Thatch aldehyde, neighbour/to ethyl-α, α-9-decenal, dimethyl dihydro cinnamon aldehyde, to isobutyl group-Alpha-Methyl dihydro cinnamon aldehyde, cis- 4-decylene-1-aldehyde, 2,5-dimethyl-2-vinyl-4-hexenoic aldehyde, trans-2-methyl-2-butene aldehyde, 3-methyl aldehyde C-9, α-sweet Orange aldehyde, 3-phenyl butyraldehyde, 2,2-dimethyl-3-hydrocinnnamic aldehyde, a tert-butyl group-Alpha-Methyl dihydro cinnamon aldehyde, geranyl epoxide second Aldehyde, trans-4-decylene-1-aldehyde, methoxy citronellal and their mixture.

The example of suitable ester includes but is not limited to：Allyl cyclohexyl propionate, allyl heptanoate, amyl alcohol acid allyl Ester, allyl hexanoate, pentyl acetate (n-amyl acetate), amyl propionate, benzyl acetate, benzyl propionate, benzyl salicylate, acetic acid Cis-3-hexene ester, citronellyl acetate, citronellyl propionate, salicylic acid cyclohexyl, 2-n-hexyl-Δ2-cyclopentenone acid esters, dimethyl Benzyl methyl esters, ethyl acetate, ethyl acetoacetate, ethyl butyrate, ethyl 2-methylbutyrate, 2 methyl valeric acid ethyl ester, acetic acid turnip Ester (acetic acid 1,3,3-trimethyl-2-norcamphane ester), cyclacet, tricyclo decenyl propionate, geranyl acetate, isobutyl Cis-3-hexenyl the ester of acid, hexyl acetate, salicylic acid cis-3-hexenyl ester, the just own ester of salicylic acid, isobornyl acetate, second Any ester in Suan, vertenex, acetic acid (-)-L-menthyl ester, verdox, methyl benzoate, two Hydrogen isojasmone acid methyl esters, acetic acid Alpha-Methyl benzyl ester, gaultherolin, acetic acid 2-phenyl chlorocarbonate, acetic acid isoprene ester, acetic acid Cypress ester, Cyclabute, phenylethyl phenylacetate, formic acid tyerpinyl ester, ortho-aminobenzoic acid citronellyl acrylate, three rings [5.2.1.0-2, 6] decyl-2-Ethyl formate, acetoacetate n-hexyl ethyl ester, the acetic acid 2-tert-butyl group-4-methyl cyclohexyl, formic acid 3,5,5-trimethyl Own ester, crotonic acid phenethyl ester, acetic acid ring ox ester, geranyl crotonate, ethyl geranate, geranyl isobutyrate, 2-n-heptylacetylene Acetoacetic ester, 3,7-dimethyl-2,6-octadienoic acid methyl esters, citronellyl valerate, 2-hexenyl cyclopentanone, ortho-aminobenzoic acid hexamethylene Ester, crotonic acid L-citronellyl acrylate, butyl crotonate, crotonic acid pentyl ester, octanoic acid citronellyl acrylate, acetic acid 9-ubidecarenone, 1 butyric acid 2-isopropyl The own ester of base-5-methyl, Pentyl benzoate, benzoic acid 2-methylbutyl butenoate (mixture with amyl benzoate), propionic acid dimethyl Benzyl methyl esters, dimethyl benzyl methyl esters, salicylic acid trans-2-hexene ester, isobutyric acid dimethyl benzyl methyl esters, formic acid 3,7- Dimethyl monooctyl ester, rhodinyl formate, rhodinyl isovalerate, rhodinyl acetate, rhodinyl butyrate, rhodinyl propionate, ethyl cyclohexyl Base ethyl ester, neryl butyrate, butyric acid tetrahydrochysene geraniol ester, myrcenyl acetate, 2,5-dimethyl-2-vinyl hex-obtusilic acid first Which ester in ester, acetic acid 2,4-Dimethylcyclohexyl-1-methyl esters, acetic acid ocimenum alcohol ester (Ocimenyl acetate), isobutyric acid, Acetic acid 6-methyl-5-hept-1 alkene ester, acetic acid 4-methyl-2-pentyl ester, 2-Methyl Butyric Acid n-pentyl ester, propyl acetate, isopropyl acetate alkene Ester, isopropyl acetate, 1-methyl cyclohexane-3-e pioic acid methyl ester, tiglic acid propyl ester, propyl group/isobutyl basic ring amyl-3-thiazolinyl-1-acetic acid Ester (α-vinyl), 2-butyl pyromucate, 2-pentenoic acid ethyl ester, (E)-methyl-3-pentenoate, acetic acid 3-methoxyl group-3-methyl Butyl ester, crotonic acid n-pentyl ester, isobutyric acid n-pentyl ester, propyl formate, furfuryl butyrate, angelic acid methyl esters, pivalic acid methyl esters, caproic acid are different Pentadiene ester, furfuryl propionate, diethyl malate, 2-Methyl Butyric Acid isopropyl ester, dimethyl malenate, bornyl formate, acetic acid Styracin, 1-(2-furyl)-1-acetone, acetic acid l-citronellyl acrylate, acetic acid 3,7-dimethyl-1,6-nonadiene-3-base ester, bar Beans bitter orange flower ester, acetic acid dihydromyrcene ester, acetic acid tetrahydrochysene laurene ester, acetic acid lavender ester, isobutyric acid 4-cyclo-octene ester, different Butyric acid ring pentyl ester, acetic acid 3-methyl-3-butene esters, allyl acetate, geranyl formate, caproic acid cis-3-hexene ester and it Mixture.

The example of suitable alcohol includes but is not limited to：Benzylalcohol, β-γ-hexenol (2-hexen-1-ol), cedrol, lemongrass Alcohol, cinnamyl alcohol, paracresol, cuminyl alcohol, dihydromyrcenol, 3,7-dimethyl-1-octanol, dimethyl benzyl carbinol, eucalyptol, Eugenol, fenchanol, geraniol, propyloxy phenyl alcohol (Hydratopic alcohol), isononyl alcohol (3,5,5-trimethyl- 1-hexanol), linalool, estragole (estragole), methyleugenol (eugenyl methyl ether), nerol, sec-n-octyl alcohol, Patchouli alcohol, benzene alcohol (3-methyl-5-phenyl-1-amylalcohol), benzyl carbinol, alpha-terpineol, tetrahydrolialool, tetrahydrochysene laurene Alcohol, 4-methyl-3 decene-5-alcohol, l-3,7-dimethyl octane-1-alcohol, 2-(furfuryl group-2)-enanthol, 6,8-dimethyl-2-nonyl alcohol, Ethyl norborny cyclohexanol, Beta-methyl hexamethylene ethanol, 3,7-dimethyl-(2), 6-octene (diene)-1-alcohol, trans-2- Hendecene-1-alcohol, 2-ethyl-2-prenyl-3-hexenol, isobutylbenzyl methyl alcohol, dimethyl benzyl carbinol, ocimenum Alcohol, 3,7-dimethyl-1,6-nonadiene-3-alcohol (cis ＆ is trans), 2,6-Dimethyl-2-octanol, alpha-terpineol, 9-decenol-1,2 (hexenyl) cyclopentanol, 2,6-dimethyl-2-heptanol, 3-methyl isophthalic acid-octene-3-alcohol, 2,6-dimethyl-5-heptene-2-alcohol, 3, 7,9-trimethyl-1,6-decadinene-3-alcohol, 3,7-dimethyl-6-nonylene-1-ol, 3,7-dimethyl-1-octyne-3-alcohol, 2,6- Dimethyl-1,5,7-eight carbon trienol-3, dihydromyrcenol, 2,6,10-trimethyl-5,9-11 carbon dienol, 2, 5-dimethyl-2-propyl group hex-4-enol-1, (Z), 3-hexenol, methyl-benzyl carbinol o-, m-, p-, 2-methyl-5-phenyl- 1-amylalcohol, 3-methylbenzene ethanol, p-methyl dimethoxy base benzyl carbinol, methyl benzyl carbinol, to methylbenzene ethanol, 3,7-diformazan Base-2-octen-1-ol, 2-methyl-6-methylene-7-octene-4-alcohol and their mixture.

The example of ketone includes but is not limited to：Oxa-ring 17 carbon-10-alkene-2-ketone, benzylacetone, benzophenone, L-Sheep's-parsley Ketone, LINL-OX, 4-(2,6,6-trimethyl-3-cyclohexene-1-base)-butyl-3-alkene-4-ketone, ethyl pentyl group ketone, α-purple sieve Ketone, β-ionone, ethyl ketone, octahydro-2,3,8,8-tetramethyl-2-acetonaphthone, α-irone, 1-(5,5-dimethyl-1-hexamethylene Alkene-1-base)-4-amylene-1-ketone, 3-nonanone, ethyl hexyl ketone, menthones, 4-methyl acetophenone, γ-methyl ionone, methyl Amyl ketone, methyl heptenone (6-methyl-5-hepten-2-one), methyl heptyl ketone, methyl hexyl ketone, δ-Moschus ketenes, 2-are pungent Ketone, 2-amyl group-3-methyl-2-cyclopentene-1-one, alismone, Alpha-Methyl ionone, 3-methyl-2-(trans-2-penta Thiazolinyl)-cyclopentenone, octenyl cyclopentanone, n-pentyl cyclopentenone, 6-hydroxyl-3,7-dimethyl-octa lactone, 2-hydroxyl-2- Cyclohexene-1-ketone, 3-methyl 4-phenyl-3-butene-2-one, 2-amyl group-2,5,5-trimethyl cyclopentanone, 2-cyclopenta ring penta Alcohol-1,5-methyl hex-2-ketone, γ-dodecalactone, δ-dodecalactone, δ-dodecalactone, nonyl lactone, δ-nonalactone, γ-pungent Lactone, δ-undecalactone, peach aldehyde and their mixture.

The example of ether includes but is not limited to：P-methylphenyl methyl ether, 4,6,6,7,8,8-vegolysen, 3,4,6,7,8- Hexahydro cyclopenta (G)-2-chromene, jara jara, methyl isobutenyl oxinane, (phantolid) 5-second Acyl group-1,1,2,3,3,6-hexamethyl indane, (tonalid) 7-acetyl group-1,1,3,4,4,6-HMT, 2-benzene second Base 3-methyl but-2-ene base ether, ethyl geranyl ether, phenethyl isopropyl ether and their mixture.

The example of alkene includes but is not limited to：Alloocimene, amphene, β-carypohyllene, cadinene, diphenyl-methane, d-lemon Lemon alkene, Lymolene, beta-myrcene, p-Methylisopropylbenzene, australene, nopinene, α-terpinenes, γ-terpinenes, different pine tar Alkene, 7-methyl-3-methylene-1,6-octadiene and their mixture.

The example of nitrile includes but is not limited to：3,7-dimethyl-6-octene nitrile, 3,7-dimethyl-2 (3), 6-nonadiene nitrile, (2E, 6Z) 2,6-nonadiene nitrile, n-dodecane nitrile and their mixture.

The example of schiff bases includes but is not limited to：Citronellyl nitrile, aldehyde C-9/artificial neroli oil, N-pungent subunit ortho-aminobenzoic acid Methyl esters (L), laurine/artificial neroli oil, 2-methyl-3-(4-cyclamen aldehyde/artificial neroli oil, anisyl propionic aldehyde/ammonia Fennel acid methyl esters, ethylaminobenzoate/laurine, citral/artificial neroli oil, 2,4-dimethyleyelohexane-3-alkene first Aldehyde/artificial neroli oil, laurine-indoles and their mixture.

The non-limiting example of aromatic includes aromatic, such as Moschus oil, civet, castoreum, ambergris, plant fragrance Agent, such as Semen Myristicae extract, Amomum cardamomum extract, Ginger P.E, cinnamomum cassia extract, patchouli oil, oil of geranium, orange Oil, mandarin oil, flores aurantii extract, cdear, vetiver, lavender, Cananga odorata extract, cordate telosma extract, sandalwood oil, bergamot Oil, fan butterfly sesame oil, spearmint oil, peppermint oil, lemon oil, lavender oil, citronella oil, oil of chamomile, caryophyllus oil, sage oil, Neroli oil, labdanum oil, eucalyptus oil, verbena oil, sensitive plant extract, narcissus extract, carrot seed extract, jasmine carry Take thing, Olibanum extract, rose extract and their mixture.

Carrier and water

When composition comprises microcapsules, composition can comprise the carrier for microcapsules.The non-limiting example of carrier Including water, silicone oil such as siloxanes D5 and other oil are such as mineral oil, isopropyl myristate and aromatic oil.Carrier should not show Write the performance affecting microcapsules.The non-limiting example of the carrier not being suitable for microcapsules includes volatile solvent such as 95% second Alcohol.

The composition comprising microcapsules can comprise based on the weight of composition about 0.1% to about 95%, and about 5% to about The carrier of 95%, or 5% to 75%.When composition comprises volatile solvent, composition can comprise based on the weight of composition About 0.01% to about 40%, about 0.1% to about 30%, or the water of about 0.1% to about 20%.

In some instances, when spraying the first composition comprising volatile solvent and the second composition comprising microcapsules When, dosage contained by the mixture of the first composition and the second composition can comprise based on the weight of composition about 0.01% to about 75%th, about 1% to about the 60%th, about 0.01% to the water of about 60% or about 5% to about 50%.

Encapsulation object

Confectionery composition can comprise microcapsules.Microcapsules can be disclosed herein or known in the art any kind of micro- Capsule.Microcapsules can have shell and the core material encapsulated by shell.The core material of microcapsules can comprise one or more aromatic.Micro- The shell of capsule can be made up of synthesizing polymeric material or naturally occurring polymer.Synthetic polymer can derive from such as oil. The non-limiting example of synthetic polymer includes：Nylon, polyethylene, polyamide, polystyrene, polyisoprene, Merlon, Polyester, polyureas, polyurethane, polyolefin, polysaccharide, epoxy resin, polyvinyl, polyacrylate and their mixing Thing.The non-limiting example of suitable shell material includes selected from following material：One or more amine are anti-with one or more aldehyde Answer product, such as the urea with formaldehyde or glutaraldehyde cross-linking, the melamine with formaldehyde crosslinking；Optionally bright with glutaraldehyde cross-linking Glue-polyphosphate coacervate；Gelatin-Arabic gum coacervate；Cross-linked silicone liquid；The polyamine reacting with polyisocyanates； Acrylate monomer and their mixture via Raolical polymerizable polymerization.Natural polymer naturally occur and Can generally extract from natural materials.The non-limiting example of naturally occurring polymer is silk, wool, gelatin, cellulose, albumen Matter and combinations thereof.

Microcapsules can be fragile microcapsule.Fragile microcapsule is configured to discharge its core material when its shell ruptures.This breaks Split and can be caused by the power putting on shell during mechanism.When measuring according to Burst Strength Test Method, microcapsules Can have the volume weighted median rupture strength of about 0.1MPa to about 25.0MPa, or within the range with 0.1 megapascal (MPa) table Any increment shown, or any scope being formed by these rupture strength values any.For example, microcapsules can have 0.5-25.0 Megapascal (MPa) (MPa) or 0.5-20.0 megapascal (MPa) (MPa), 0.5-15.0 megapascal (MPa) (MPa) or 0.5-10.0 million The volume weighted median rupture strength of Pascal (MPa).

As measured according to the method for testing of the volume weighted median particle diameter for measuring microcapsules described herein, microcapsules Can have the volume weighted median particle diameter of 2 microns to 80 microns, 10 microns to 30 microns or 10 microns to 20 microns.

Microcapsules can have the weight ratio of various core material and shell.The core material of microcapsules and the ratio of shell can more than or etc. In：10% to 90%, 30% to 70%, 50% to 50%, 60% to 40%, 70% to 30%, 75% to 25%, 80% ratio 20%th, 85% to 15%, 90% to 10% and 95% to 5%.

Microcapsules can have the shell being made up of any material of any size known in the art, shape and structure.Some Or all shell can comprise polyacrylate material, such as polyacrylate random copolymer.For example, polyacrylate random copolymerization Thing can have overall polyacrylate quality, and it includes selected from following composition：The 0.2%-of overall polyacrylate quality The amine content of 2.0%；The carboxylic acid of the 0.6%-6.0% of overall polyacrylate quality；With the amine content of 0.1%-1.0% with total The combination of the carboxylic acid of the 0.3%-3.0% of body polyacrylate quality.

When the shell of microcapsules comprises polyacrylate material, the 5-of the gross mass of polyacrylate material constructible hull 100%, or any percentage integer value or any scope being formed by these percent value any in the range of this.For example, At least the 5% of the gross mass of polyacrylate material constructible hull, at least 10%, at least 25%, at least 33%, at least 50%, At least 70% or at least 90%.

Microcapsules can have multiple thickness of the shell.The general thickness of the shell of microcapsules can be 1-2000 nanometer, or this scope Interior any nanometer integer value or any scope being formed by these one-tenth-value thickness 1/10s any.As non-limiting example, microcapsules can There is the shell that general thickness is 2-1100 nanometer.

Microcapsules also can encapsulate one or more beneficial agents.One or more beneficial agents include but is not limited to any combination One or more in chromogenic substrate, dyestuff, freshener, hot sensitizer, aromatic, oil, pigment.When beneficial agent comprises aromatic When, described aromatic can include about 2% to about the 80%th, about 20% to about the 70%th, about 30% to about 60% have more than-0.5, Or the perfume base of the even about ClogP of 0.5 to about 4.5.In some instances, the aromatic of encapsulating can have less than the 4.5th, little In 4 or the ClogP less than 3.In some instances, microcapsules can be anion, cation, amphion, or has neutrality Electric charge.One or more beneficial agents can be in solid and/or the form of liquid.One or more beneficial agents can comprise any combination of One or more aromatic any kind of known in the art.

Microcapsules also can encapsulate the oil-soluble material in addition to beneficial agent.Oil-soluble material in addition to the beneficial agent of encapsulating Non-limiting example include：C₄-C₂₄The monoesters of aliphatic acid and glycerine, diester and three esters；Isopropyl myristate, soybean oil, Hexadecylic acid, methyl esters, Permethyl 99A and combinations thereof.Oil-soluble material can have about 4 or bigger, at least 4.5 or bigger, At least 5 or bigger, at least 7 or bigger or at least 11 or bigger ClogP.

The shell of microcapsules can comprise product in the presence of comprising the second mixture of emulsifying agent for first mixture, institute State the first mixture and comprise i) oil-soluble or dispersiveness amine and ii) polyfunctional acrylic ester or methacrylate monomers or oligomeric The product of thing, oil-soluble acid and initiator, described emulsifier package containing water-soluble or water-dispersible acrylic's alkyl acid copolymerization Thing, alkali metal or alkali metal salt and optional aqueous phase initiator.In some instances, described amine is acrylic-amino alkyl Ester or amino alkyl methacrylate.

Microcapsules can include core material and the shell of parcel core material, and wherein said shell includes：Selected from acrylic-amino alkyl Ester, acrylic acid alkylaminoalkyl ester, propenoic acid dialkyl aminoalkyl ester, amino alkyl methacrylate, metering system Dialkylaminobenzoic acid amino Arrcostab, methacrylates, methacrylic acid tert-butyl group aminoethyl ester, methyl Diethylaminoethyl acrylate, dimethylaminoethyl methacrylate, methacrylic acid dipropyl aminoethyl ester and they Multiple amine monomers of mixture；With multiple polyfunctional monomers or multifunctional oligomer.

The non-limiting example of microcapsules includes the microcapsules containing shell and the core material encapsulated by described shell：This shell comprises Selected from diethylaminoethyl methacrylate, dimethylaminoethyl methacrylate, methacrylic acid tert-butyl group aminoethyl ester；With And the amine of combinations thereof；Described core material comprise based on the weight of microcapsules about 10% to about 60% be selected from C₄-C₂₄Fat The monoesters of acid and glycerine, diester and three esters；Isopropyl myristate, soybean oil, hexadecylic acid, methyl esters, Permethyl 99A and they The material of combination；Spices material with about 10% to about 90% based on the weight by microcapsules；Wherein said microcapsules have 0.1MPa to 25MPa, the volume weighting rupture strength of preferred 0.8MPa to 20MPa, more preferably 1.0MPa to 15MPa, Qi Zhongsuo State microcapsules and there is the volume weighted median particle diameter of 10 microns to 30 microns.

It is known for preparing the method for microcapsules.For the various method of microencapsulation and illustrative methods and material Material is shown in United States Patent (USP) 6,592,990；United States Patent (USP) 2,730,456；United States Patent (USP) 2,800,457；United States Patent (USP) 2,800, 458；United States Patent (USP) 4,552,811；With in United States Patent (USP) 2006/0263518A1.

Microcapsules can be spray-dried to form the microcapsules of spray drying.In addition to microcapsules, composition also can wrap Containing the one or more additional delivery system for providing one or more beneficial agents.The class of one or more additional delivery systems Type may differ from microcapsules.For example, wherein microcapsules are frangible and encapsulate aromatic, and additional delivery system can be additional virtue Pastil delivery system, such as humidity trigger fragrance delivery system.Humidity triggers the non-limiting example of fragrance delivery system Including cyclic oligosaccharide, starch (or other polysaccharide materials), starch derivatives and combinations thereof.

Composition still comprises Parent Aromatic agent and one or more may be the same or different in the encapsulating of Parent Aromatic agent Aromatic.For example, composition can comprise Parent Aromatic agent and non-Parent Aromatic agent.Parent Aromatic agent refers to be scattered in whole group Compound and generally not encapsulated when adding to composition aromatic.Herein, non-Parent Aromatic agent refers to be different from Parent Aromatic agent and the aromatic that encapsulated material is encapsulated before introducing composition.Between aromatic and non-Parent Aromatic agent The non-limiting example of difference includes the difference of chemical composition.

Suspending agent

Composition described herein can comprise one or more and for the suspending agent of microactuator suspension capsule and be scattered in composition Other water-insoluble materials.The concentration range of suspending agent can be for by weight of the composition about 0.01% to about the 90%th, Or about 0.01% to 15%.

The non-limiting example of suspending agent includes anionic polymer, cationic polymer and non-ionic polymers.Described The non-limiting example of polymer includes：The crosslinked acrylic acid polymer of the entitled carbomer of polyvinyl, such as CTFA；Fine Dimension element derivative and modified cellulosic polymeric, such as methylcellulose, ethyl cellulose, hydroxyethyl cellulose, hydroxypropyl first Base cellulose, NC Nitroncellulose, cellulose sodium sulfate, sodium carboxymethylcellulose, avicel cellulose, cellulose powder, polyethylene Pyrrolidones, polyvinyl alcohol, guar gum, hydroxypropyl guar gum, xanthans, Arabic gum, bassora gum, galactan, carob Glue, guar gum, karaya, carrageenan, pectin, agar, temperature cypress seed (sub), starch (rice, corn, potato, Wheat), algin (algae extract)；Microbial polymer, such as glucan, succinoglucan, Propiram；Based on starch Polymer, such as CMS, methylhydroxypropyl starch；Based on the polymer of alginic acid, such as mosanom and alginic acid；The third two Alcohol ester；Acrylate polymer, such as Sodium Polyacrylate, polyethyl acrylate, polyacrylamide and ethylene imine；And nothing Machine water-soluble substances, such as bentonite, Magnesiumaluminumsilicate, LAPONITE, hectorite and silicic acid anhydride.Other suspending agents can wrap Include but be not limited to konjaku, gellan gum and the Copolymer of Methyl Vinyl Ether/Maleic Anhydride crosslinked with decadinene (for example).

Other non-limiting examples of suspending agent include：Crosslinked polyacrylate polymers, such as carbomer, with trade name For934、940、950、980、981、Ultrez 10、Ultrez 20、Ultrez 21、Ultrez 30、ETD2020、ETD2050、TR-1 andTR-2 is purchased from The Lubrizol Corporation；Acrylate/stearyl ether-20 methacrylate copolymer, with trade name ACRYSOL^TM22 are purchased from Rohmand Hass；Acrylate/beheneth-25 methacrylate copolymers Thing, the trade name to include Aculyn-28 is purchased from Rohm and Hass, and with Volarest^TMFL is purchased from Croda；Nonyl epoxide Ethyl cellulose, with trade name Amercell^TMPOLYMER HM-1500 is purchased from Amerchol；Methylcellulose, trade nameHydroxyethyl cellulose, trade nameHydroxypropyl cellulose, trade nameCetyl hydroxyethyl cellulose, trade name67, supplied by Hercules；Epoxy Ethane and/or expoxy propane based polyalcohol, trade namePEGs, POLYOX WASRs and FLUIDS, it is all supplied by Amerchol；Ammonium acryloyldime-thyltaurate/carboxyethyl-acrylate-cross-linked polymer is such asTAC copolymer, AVC is such asAVS copolymer, propylene Acyl dimethyltaurine sodium/VP cross-linked polymer is such asAVS copolymer, ammonium acryloyldime-thyltaurate/20 Dialkyl group APEO-25 Methacrylate Crosspolymer is such asBVL or HMB, it is all purchased from Clariant Corporation；Polyacrylate cross-linked polymer-6, with trade name Sepimax^TMZen is purchased from Seppic；With And vinyl pyrrolidone and acrylic acid cross-linked copolymer, such as the UltraThixTM P-100 polymerization purchased from Ashland Thing.

Other non-limiting examples of suspending agent include the suspending agent of crystallization, and it can be classified as acyl derivative, length Chain amine oxide and their mixture.

Other non-limiting examples of suspending agent include the glycol ester of aliphatic acid, have about 16 to about 22 in some respects Those of individual carbon atom；Ethylene glycol stearate, including monostearate and distearate, in some respects, distearyl acid Ester comprises the monostearate of less than about 7%；The alkanolamide of aliphatic acid, has about 16 to about 22 carbon atoms or about 16 To 18 carbon atoms, its example include stearic acid monoethanolamide, Stearic acid diethanolamine salt, stearic monoisopropanolamide and Stearic acid monoethanolamide stearate；Long chain acyl derivatives, including the long-chain ester of LCFA (such as stearic acid tristearin Base ester, palmitic acid spermaceti ester etc.)；The long-chain ester of long chain alkanol amides (such as stearmide diglycollic amide distearate, Stearmide single ethanol amide stearate)；With glyceride (for example glyceryl distearate, trihydroxy tristerin, Tribehenin essence), its commercial example isR, is purchased from Rheox, Inc.Other non-limiting examples of suspending agent include long The alkanolamide of chain acyl derivative, the glycol ester of long-chain carboxylic acid, long chain amine oxide and long-chain carboxylic acid.

Other non-limiting examples of suspending agent include Long chain acyl derivatives, and it includes N, N-dialkyl acylamino-benzene first Acid and soluble-salt (such as Na, K), the especially N in such, N-bis-(hydrogenation) C₁₆、C₁₈With butter amido benzoic acid Class, it is commercially available from Stepan company (Northfield, Ill., USA).

The non-limiting example of the long chain amine oxide being useful as suspending agent includes alkyl dimethyl amine oxide (such as stearyl Dimethyl amine).

Other nonrestrictive suitable suspending agents include having the primary of the fatty alkyl moieties containing at least about 16 carbon atoms Amine (its example includes palmitamide or octadecylamine) and there are two respectively fatty alkyl moieties secondary containing at least about 12 carbon atoms Amine (its example includes two palmityl amine or two (h-tallow base) amine).Other non-limiting examples of suspending agent include two (h-tallow base) phthalic amide and crosslinked maleic anhydride-methyl vinyl base ether copolymer.

Colouring agent

Confectionery composition can comprise colouring agent.Colouring agent can be the form of pigment.As used herein, term " pigment " represents While reflecting the light of some wavelength, absorb the light of other wavelength, and the solid of appreciable luminescence is not provided.Available pigment Including but not limited to expand inert mineral (e.g., talk, calcium carbonate, clay) to or processed (e.g., by siloxanes or other coatings In order to prevent granules of pigments agglomeration again or in order to change the polarity (hydrophobicity) of pigment) those.Pigment can be used to give not Transparency and color.It is typically considered safe any pigment (such as in the C.T.F.A.ization being herein incorporated by reference Cosmetic Ingredient Dictionary, the 3rd edition, cosmetic and Fragrance Association, Inc., Washington, D.C. (1982) listed those in) may be included in composition described herein.The non-limiting example of pigment includes body pigment, nothing Machine Chinese white, inorganic color pigment, pearling agent etc..The non-limiting example of pigment includes talcum, mica, magnesium carbonate, carbonic acid Calcium, magnesium silicate, Magnesiumaluminumsilicate, silica, titanium dioxide, zinc oxide, red ferric oxide, yellow ferric oxide, Black Rouge, ultramarine face Material, polyethylene powders, methacrylate powder, Polystyrene powder, silk powder, avicel cellulose, starch, metatitanic acid mica, oxygen Change ferrotitanium acid cloud mother, bismoclite etc..Aforesaid pigments may be used alone or in combination use.

Other non-limiting examples of pigment include inorganic powder, such as natural gum, chalk, bleaching earth, kaolin, thin,tough silk cloud Mother, muscovite, phlogopite, synthetic mica, rubellan, biotite, lithia mica, vermiculite, alumina silicate, starch, smectic clays, Alkyl and/or trialkyl aryl ammonium smectites, the aluminium-magnesium silicate of chemical modification, organically-modified montmorillonitic clay, aluminium hydrosilicate, Ocentyl succinic pyrolysismethod aluminium starch ester, barium silicate, calcium silicates, magnesium silicate, strontium silicate, metal salt, magnesium, siallite, Zeolite, barium sulfate, calcined calcium sulfate hemihydrate (calcined gypsum), calcium phosphate, fluor-apatite, hydroxyapatite, ceramic powder, metallic soap are (stearic Acid zinc, magnesium stearate, zinc myristate, calcium palmitate and aluminum stearate), gluey silica and boron nitride；Organic dust is all Such as polyamide resin powders (nylon powder), cyclodextrin, polymethylmethacrylate powder, styrene and acrylic acid copolymer Powder, benzoguanamine resin powder, poly-(tetrafluoroethene) powder and carbopol, cellulose powder, such as ethoxy are fine Dimension element and sodium carboxymethylcellulose, Tego-stearate；Inorganic white pigment, such as magnesia.Pigment non-limiting Example includes nanometer colouring agent and the multi-coated interference pigment deriving from BASF, such as derives from the Sicopearls of BASF.Pigment can enter Row surface treatment, so that color is more stable and easily prepares.The non-limiting example of pigment include aluminium salt, barium salt or calcium salt or Color lake.Some other non-limiting examples of colouring agent include red 3 aluminium color lakes, red 21 aluminium color lakes, red 27 aluminium color lakes, redness 28 aluminium color lakes, red 33 aluminium color lakes, yellow 5 aluminium color lake, yellow 6 aluminium color lake, yellow 10 aluminium color lake, orange 5 aluminium color lakes and blue 1 Aluminium color lake, red 6 barium color lakes, red 7 calcium color lakes.

Colouring agent is alternatively dyestuff.Non-limiting example include red 6th, red 21st, brown, yellowish-brown and Sienna dyes, Yellow the 5th, yellow the 6th, red 33rd, red 4th, blue 1st, purple 2 and their mixture.Other non-limiting examples of dyestuff Including fluorescent dye such as fluorescein.

Other compositions

Composition can comprise other compositions, as antioxidant, ultraviolet inhibitors such as sun-screening agent and physical sunscreen frost, ring are stuck with paste Essence, quencher and/or skin care actives.The non-limiting example of other compositions includes 2-ethylhexyl-p-methoxyl group meat Cinnamic acid ester；2-[4-(lignocaine)-2-hydroxy benzoyl] hexyl-benzoate；The 4-tert-butyl group-4'-methoxy dibenzoyl first Alkane；2-hydroxyl-4-methoxybenzene-acyl benzene；2-PHENYLBENZIMIDAZOLE-5-SULFONIC ACID；Octocrylene；Zinc oxide；Dioxy Change titanium；Vitamin, such as vitamin C, Cobastab, VitAVitE and their derivative；Flavones and flavonoids； Amino acid, such as glycine, tyrosine etc.；Carotenoid and carrotene；Chelating agent, as EDTA, lactate, citrate, with And their derivative.

Using method

The compositions disclosed herein person's of may be used as daily practice or a part for scheme, be applied to one or more On skin surface and/or one or more mammalian keratinous tissue surface.In addition or alternatively, the composition of this paper can To be used on the basis of " on-demand ".Composition can be applied to any goods such as yarn fabric, or any absorbent article, bag Include but be not limited on feminine hygiene products, diaper and adult incontinence product.For example, when distributor described herein, assembly and combination When the combination of thing is designed subtly for use as essence spices spraying, it will be appreciated that such composition also is used as body spray, female Property spraying, adult-incontinence spraying, baby spraying or other spraying.The size of distributor described herein, shape and aesthetics design can It is extensively varied.

Method of testing

It should be appreciated that owing to this type of invention is described in this paper and claimed in herein, in present patent application The method of testing disclosed in Test Methods section should be used to determine the analog value of parameter of invention of applicant.

(1) Burst Strength Test Method

Those skilled in the art it will be recognized that in order to from finished product extract and separate microcapsules, various scheme can be built, And it will be recognized that this type of method need by compare microcapsules are joined in finished product and in finished product extract before and it After the gained measured value that records confirm.Then the microcapsules of separation are formulated in deionization (DI) water and are used for form slurries Characterize.It should be appreciated that the rupture strength of the microcapsules extracting from finished product can be changed +/-15% by ranges described herein, because Elapsing in time, finished product can change the rupture strength of microcapsules.

The percentage of the microcapsules in the range of belonging to claimed rupture strength for calculating, carries out three kinds not Same measurement, and use the figure of two gained.Three kinds of independent measurements are respectively：I) the weighted volumetrically size distribution of microcapsules (PSD)；Ii) diameter of at least 10 independent microcapsules in each of 3 specified size scopes；With iii) those identical 30 The bursting force of individual or more independent microcapsules.Two figures being formed are respectively：I) the volume weighting granularity collected by place above The curve map of distributed data；And derive from ii above) and iii) between the microcapsule diameter of data collected by place and rupture strength The curve map of the modelling distribution of correlation.In modelling correlation curve figure makes claimed strength range Microcapsules can be denoted as the concrete region under volume weighting PSD curve, the gross area percentage being then calculated as under curve Ratio.

A.) AccuSizer 780 AD instrument (or equivalent) and subsidiary software CW788 1.82 editions is used (Particle Sizing Systems, Santa Barbara, California, U.S.A.), via single particle optical sensing (SPOS) (also known as optical particle counting (OPC)), measure the following condition of the volume weighting size distribution (PSD) of microcapsules with Option and installment instrument：Flow=1mL/s；Dimension threshold lower limit=0.50 μm；Sensor model number=LE400-05SE；Automatic dilution =open；Acquisition time=120s；Passage numeral=512；Container fluid volume=50mL；Maximum repeatability=9200.By with Water rinses makes sensor enter cold conditions and start measurement, until background count is less than 100.Introduce microcapsule suspensions sample, and And if necessary, by automatic dilution, regulate grain density with DI water, obtain the grain count of at least 9200/mL.At 120 seconds Time period in, analyze described suspension.The volume weighting PSD data of gained is drawn and record, and measure mean value, 10th percentile and the 90th percentile.

B.) measure the diameter of independent microcapsules by computer-controlled micromanipulation instrument system and rupture force value (also It is referred to as explosion force value), described system has lens and a camera that can make microcapsules imaging, and has and be connected to power sensing Fine flush end probe (such as 403A type, be purchased from Aurora Scientific Inc (Canada) or equivalent) of device, as following Described in document：Zhang, Z. et al. (1999) " Mechanical strength of single microcapsules Determined by a novel micromanipulation technique. " J.Microencapsulation, the 16th Rolled up for the 1st phase, the 117-124 page, and：Sun, G. and Zhang, Z. (2001) " Mechanical Properties of Melamine-Formaldehyde microcapsules. " J.Microencapsulation, the 5th phase of volume 18,593- Page 602, and can obtain at University of Birmingham (Edgbaston, Birmingham, UK).

C.) it is placed on a microcapsule suspensions in glass microscope slide, and if being dried at ambient conditions Dry minute, with the sparse individual layer removing water and obtain independent particle on the slide being dried.Regulate on demand in suspension The concentration of microcapsules, to obtain suitable grain density on slide glass.More than one slide goods may be needed.

D.) then slide is placed on the sample fixed station of micromanipulation instrument.Select one or more slide On 30 or more microcapsules be used for measuring so that in each of three preliminary dimension bands, there is at least ten institute Select microcapsules.Each size band refers to derive from the microcapsule diameter of the volume weighting PSD that Accusizer-generates.The three of particle Individual size band is：Average diameter +/-2 μm；10th percentile diameter +/-2 μm；With the 90th percentile diameter +/-2 μ m.Get rid of from screening technique and present shrivelled, seepage or impaired microcapsules, and do not measure.

E.) for each in 30 selected microcapsules, by the determining image microcapsule diameter on micromanipulator simultaneously And record.Then same microcapsules are compressed between two flat surfaces by the speed with 2 μm/s, i.e. flush end power probe and glass Microslide, until microcapsules rupture.During pressing step, continuous measuring probe power, and pass through micromanipulation instrument The data collecting system record of device.

F.) use the diameter recording and suppose spheric granules (π r2, wherein r is the radius of the front particle of compacting), calculating every The area of section of individual selected microcapsules.By the power probe measurement values being recorded, measure the bursting force of particle selected by each, as following Described in document：Zhang, Z. et al. (1999) " Mechanical strength of single microcapsules Determined by a novel micromanipulation technique. " J.Microencapsulation, the 16th Rolled up for the 1st phase, the 117-124 page, and：Sun, G. and Zhang, Z. (2001) " Mechanical Properties of Melamine-Formaldehyde microcapsules. " J.Microencapsulation, the 5th phase of volume 18,593- Page 602.

G.) by with bursting force (in units of newton) divided by the area of section of corresponding microcapsules calculating, calculate 30 Or the respective rupture strength of more microcapsules.

H.) on the curve map to rupture strength for the microcapsule diameter, by power regressive trend line to all 30 or more Raw data points matching, the modelling to generate correlation between microcapsule diameter and rupture strength is distributed.

I.) the microcapsules percentage with specified intensity range implosion intensity level identified below：Observing and nursingization is related to Linearity curve figure, to determine the position that curve intersects to related rupture strength limiting value, is then read out corresponding to those strength degrees The capsule size limiting value of value.Then make these capsule size limiting values be positioned in volume weighting PSD curve map, thus know Other PSD area under a curve, it is corresponding to belonging to the microcapsules part in specified intensity range.

Then it is the gross area percentage under PSD curve by the identified areal calculation under PSD curve.This percentage represents Belong to the microcapsules percentage in the range of specific rupture strength.

(2)ClogP

" logP of calculating " (ClogP) by the segmentation method of Hansch and Leo measure (with reference to A.Leo, Comprehensive Medicinal Chemistry, volume 4, C.Hansch, P.G.Sammens, J.B.Taylor and C.A.Ramsden edits, page 295, Pergamon Press, and 1990, described document is herein incorporated by reference). ClogP value (can be purchased from Irvine, the Daylight of California U.S.A. by the program using " CLOGP " Chemical Information Systems Inc.) calculate, or use Advanced Chemistry Development (ACD/Labs) software V11.02Calculate.

(3) boiling point

By the ASTM method D2887-04a of ASTM International, " Standard Test Method for Boiling Range Distribution of Petroleum Fractions by Gas Chromatography, " measurement Boiling point.

(4) volume weight fraction

Measure volume weight divide via single particle optical sensing (SPOS) (also referred to as optical particle counting (OPC)) method Number.Via Santa Barbara California, the Particle Sizing Systems supply of U.S.A. AccuSizer 780/AD or equivalent measure volume weight fraction.

Process：

1) by making water be flushed through sensor, sensor is placed in cold conditions.

2) confirm background count less than 100 (if being more than 100, continue flushing).

3) particulate level thing is prepared：The shake particle of about 1ml is moved to be filled with in the blender of about 2 glasss of DI water.Will It is blended.Being moved to about 1ml in the DI water of 50ml through diluting blended particles.

4) particulate level thing is measured：It is moved to double dilution standard things of about 1ml in Accusizer bulb.Press beginning Measurement-automatic dilution (start measurement-Autodilution) button.By checking that status bar confirms grain count More than 9200.If counting is less than 9200, presses stopping and injecting more Multi-example 10 times.

5) after the measurement, immediately the soap (5%Micro 90) of a full pipette is injected sphere (bulb) and presses Start auto-flushing circulation (Start Automatic Flush Cycles) button.

(5) for measuring the method for testing of the volume weighted median particle diameter of microcapsules

Those skilled in the art it will be recognized that in order to from finished product extract and separate microcapsules, various scheme can be built, And it will be recognized that this type of method need by compare microcapsules are joined in finished product and in finished product extract before and it After the gained measured value that records confirm.Then the microcapsules of separation are formulated into form capsule slurries in deionized water, with Sign for size distribution.

Use the Accusizer 780A that manufactured by Particle Sizing Systems (Santa Barbara CA) or Equivalent measures the volume weighted median particle diameter of microcapsules.Use size grade scale thing (as purchased from Duke/Thermo-Fisher- Scientific Inc. (Waltham, Massachusetts, USA)) by 0 to 300 μm of calibration instrument.For particle size Sample and dilutes this solution of about 1g in about 25g's by diluting the capsule slurries of about 1g in the deionized water of about 5g further Prepared by water.The sample diluting most of about 1g is added in Accusizer, and test starts, and uses automatic dilution parts. Accusizer should be by with more than 9200 countings/s reading.If counting is less than 9200, additional sample should be added.Dilution test Sample, until 9200 countings/s, then should begin the evaluation at.After test 2 minutes, Accusizer will show result, including body Long-pending weighted median particle diameter.

Embodiment

The following example is only given with illustrative purpose, may not be interpreted as limitation of the present invention, because its many changes Type is feasible.

In an embodiment, except as otherwise noted, all concentration are all listed with percentage by weight, and eliminate secondary thing Matter, diluent, filler etc..Therefore, listed preparation includes listed component and any time be associated with this component Want material.To those skilled in the art it is readily apparent that the selection of these micro substances will be according to being chosen to Prepare the Physical and chemical characteristics of the concrete composition of invention as described herein and different.

Embodiment 1 polyacrylate microcapsules

Will be by 128.4g aromatic oil, 32.1g isopropyl myristate, 0.86g DuPont Vazo-67,0.69g Wako The oil solution of Chemicals V-501 composition adds in 35 DEG C of temperature control steel jacketed reactors, and described reactor is with 1000rpm (4 ends, 2 " the smooth grinding blade of diameter) mix and there is the blanket of nitrogen applying with 100cc/min.Oil solution is existed It is heated to 70 DEG C in 45 minutes, keep 45 minutes at 75 DEG C, and in 75 minutes, be cooled to 50 DEG C.This is referred to as oil solution A.

In reaction vessel, under 25 degrees Celsius, prepare being dispersed therein by 2.40 grams of Celvol 540 polyvinyl alcohol The aqueous solution of 300g deionized water composition.Heat the mixture to 85 degrees Celsius and keep 45 minutes.Solution is cooled to 30 Degree Celsius.Add the Wako Chemicals V-501 initiator of 1.03 grams and 40% sodium hydroxide solution of 0.51 gram.By molten Liquid is heated to 50 DEG C, and keeps solution at such a temperature.

Add in oil solution A 0.19 gram methacrylic acid tertiary fourth amino ethyl ester (Sigma Aldrich), 0.19 gram The Sartomer CN975 (Sartomer, Inc.) of β-carboxy ethyl acrylate (Sigma Aldrich) and 15.41 grams.Will Acrylate monomer is mixed in oil phase 10 minutes.This is referred to as oil solution B.Use the oblique leaf turbine type stirring with 4 blades The Caframo blender of device.

In the reactor, nitrogen envelope aqueous solution top is started.Under minimal mixing, start to shift oil solution B In the aqueous solution of reactor.Mixing is increased to 1800-2500rpm, carries out 60 minutes, to emulsify oil phase to the aqueous solution In.After grinding completes, with 3, " propeller persistently mixes with 350rpm.Batch of material is kept 45 minutes at 50 DEG C, in 30 minutes Improve temperature to 75 DEG C, keep 4 hours at 75 DEG C, in 30 minutes, be heated to 95 DEG C then keep 6 hours at 95 DEG C. Then batch of material is allowed to be cooled to room temperature.

The microcapsules of gained have the median particle of 12.6 microns, the rupture strength of 7.68 ± 2.0MPa, and in rupture When 51% ± 20% deformation.

Embodiment 2 polyacrylate microcapsules

Will be by 96g aromatic oil, 64g isopropyl myristate, 0.86g DuPont Vazo-67,0.69g Wako The oil solution of Chemicals V-501 composition adds in 35 DEG C of temperature control steel jacketed reactors, and described reactor is with 1000rpm (4 ends, 2 " the smooth grinding blade of diameter) mix and there is the blanket of nitrogen applying with 100cc/min.Oil solution is existed It is heated to 70 DEG C in 45 minutes, keep 45 minutes at 75 DEG C, and in 75 minutes, be cooled to 50 DEG C.This is referred to as oil solution A.

The microcapsules of gained have the median particle of 12.6 microns, the rupture strength of 2.60 ± 1.2MPa, when rupture The deformation of 37% ± 15%.

Embodiment 3 polyacrylate microcapsules

In the reactor, nitrogen envelope aqueous solution top is started.Under minimal mixing, start to shift oil solution B In the aqueous solution of reactor.Mixing is increased to 1300-1600rpm, carries out 60 minutes, to emulsify oil phase to the aqueous solution In.After grinding completes, with 3, " propeller persistently mixes with 350rpm.Batch of material is kept 45 minutes at 50 DEG C, in 30 minutes Improve temperature to 75 DEG C, keep 4 hours at 75 DEG C, in 30 minutes, be heated to 95 DEG C then keep 6 hours at 95 DEG C. Then batch of material is allowed to be cooled to room temperature.

The microcapsules of gained have the median particle of 26.1 microns, the rupture strength of 1.94 ± 1.2MPa, when rupture The deformation of 30% ± 14%.

Embodiment 4 polyacrylate microcapsules

In the reactor, nitrogen envelope aqueous solution top is started.Under minimal mixing, start to shift oil solution B In the aqueous solution of reactor.Mixing is increased to 2500-2800rpm, carries out 60 minutes, to emulsify oil phase to the aqueous solution In.After grinding completes, with 3, " propeller persistently mixes with 350rpm.Batch of material is kept 45 minutes at 50 DEG C, in 30 minutes Improve temperature to 75 DEG C, keep 4 hours at 75 DEG C, in 30 minutes, be heated to 95 DEG C then keep 6 hours at 95 DEG C. Then batch of material is allowed to be cooled to room temperature.

The microcapsules of gained have the median particle of 10.0 microns, the rupture strength of 7.64 ± 2.2MPa, when rupture The deformation of 56% ± 20%.

Embodiment 5 polyureas/carbamate microcapsules

By the deionized water by Celvol 523 polyvinyl alcohol (Celanese Chemicals) of 6.06g and 193.94g The aqueous solution of composition at room temperature joins in the reactor of temperature control steel jacketed.Then by by the flavouring agent A of 75g and The oil solution that the Desmodur N3400 (polymerization hexamethylene diisocyanate) of 25g forms joins in reactor.Described mixed Compound propeller (4 tips, 2 " diameter, smooth grinding blade：2200rpm) emulsification is to obtain desired emulsion droplet chi Very little.Then, use Z-shaped propeller with 450rpm mixing gained emulsion.Then will be by 47g water and 2.68g TEPN group The aqueous solution becoming joins in emulsion.Then it is heated to 60 DEG C, keep 8 hours at 60 DEG C, and allow to cool to room temperature. The median particle of the microcapsules of gained is 10 microns.

Embodiment 6 polyureas/carbamate microcapsules

By the fragrance A fragrance to 5.69 grams adds the isophorone diisocyanate (Sigma of 4.44 grams Aldrich) oil phase is prepared.Under 10 degrees Celsius, by by the ethylenediamine (Sigma Aldrich) of 1.67 grams and 0.04 gram 1,4-diazabicylo [2.2.2] octane (Sigma Aldrich) mixes the polyvinylpyrrolidone K-of 5 weight % to 40 grams 90 (Sigma Aldrich) aqueous solution prepares aqueous phase.Then, to the polyvinylpyrrolidone K-of 15.0 gram of 5 weight % While 90 (Sigma Aldrich) aqueous solution adds oil phase content, use and there is 3-blade turbine agitators Janke＆Kunkel IKA Laboretechnik RW20 DZM motor, stirs described mixture about 9 minutes with 1400RPM. Then, aqueous phase is added dropwise in 6.5 minutes to emulsification oil phase, under 1400RPM, continues stirring simultaneously.Continue to stir Mix 23 minutes, then mixing speed is reduced to 1000RPM.Again after 3.75 hours, mixing speed is reduced to 500RPM, and continue to stir 14 hours.Through 2 hours, begin to warm up dispersion to 50 degrees Celsius.Aging glue under 50C Capsule 2 hours, then collects microcapsules.The microcapsules of gained have the median particle of 12 microns.

Embodiment 7 polyacrylate microcapsules

Following preparation has the polyacrylate microcapsules of the feature being shown in table 3.Will by 112.34g aromatic oil, 12.46g isopropyl myristate, the oil of 2.57g DuPont Vazo-67,2.06g Wako Chemicals V-501 composition Solution adds in 35 DEG C of temperature control steel jacketed reactors, and with 1000rpm, (4 ends, 2 " the smooth of diameter grinds described reactor Mill blade) mix and there is the blanket of nitrogen applying with 100cc/min.Oil solution was heated to 70 DEG C in 45 minutes, 75 Keep 45 minutes at DEG C, and in 75 minutes, be cooled to 50 DEG C.This is referred to as oil solution A.

Add in oil solution A 0.56 gram methacrylic acid tertiary fourth amino ethyl ester (Sigma Aldrich), 0.56 gram The Sartomer CN975 (Sartomer, Inc.) of β-carboxy ethyl acrylate (Sigma Aldrich) and 46.23 grams.Will Acrylate monomer is mixed in oil phase 10 minutes.This is referred to as oil solution B.Use the oblique leaf turbine type stirring with 4 blades The Caframo blender of device.

The spray drying of embodiment 8 perfume microcapsule

With the speed of 1kg/h, the microcapsules in embodiment 1 are pumped into concurrent spray drier (Niro Production Minor, 1.2 rice diameters) in, and use with 18, centrifugal impeller (100mm diameter) atomization that 000RPM speed rotates.It is dried Device operating condition is：Air-flow is 80kg/h, and entering air temperature is 200 degrees Celsius, and outlet temperature is 100 degrees Celsius, drier Work under the pressure of-150 millimeters of water vacuums.Dried powder is collected in the bottom of cyclone separator.The microcapsules tool collected There is the particle diameter of about 11 microns.Equipment used by spray-drying process is available from following supplier：IKA Werke GmbH＆Co.KG, Janke and Kunkel Str.10, D79219 Staufen, Germany；Niro A/S Gladsaxevej 305, P.O.Box 45,2860Soeborg, Denmark and Watson-Marlow Bredel Pumps Limited, Falmouth, Cornwall, TR11 4RU, England.

Embodiment 9

The micro-glue described in embodiment 1-8 can be used as shown in the first composition of the percentage of following instruction Capsule.

It should be appreciated that running through each greatest measure limit that this specification provides includes each lower numerical limitation, as This lower numerical limitation is clearly write herein.Run through each minimum value limit that this specification is given will include each more High numerical limitation, as herewith each higher numerical limitation is clearly write herein.Run through each numerical value that this specification provides Scope will include falling each the narrower number range in this broader numerical, as this type of narrower number range is herein Clearly write completely.

Dimension disclosed herein and value are not understood as being strictly limited to cited exact numerical.On the contrary, unless additionally Indicating, otherwise each such dimension is intended to indicate that described value and around the functionally equivalent scope of this value.For example, it is disclosed as The dimension of " 40mm " is intended to indicate that " about 40mm ".

Unless expressly excluded or otherwise limited, each document otherwise cited herein, including this application is wanted Ask any cross reference of its priority or benefit or related patent or application and any patent application or patent, all in full with The mode quoted is expressly incorporated herein.Quoting of any document is not relative to any disclosed in this invention or herein by right to it The accreditation of prior art of claim protection, or be not to its individually or with any other bibliography or multiple with reference to literary composition The combination offered proposes, advises or discloses the accreditation of this type of invention any.If additionally, in this document term any implication or Definition conflicts mutually with any implication being herein incorporated by reference in the literature same term or definition, will be to compose in this document Give the implication of this term or definition is as the criterion.

Although having illustrate and described the particular of the present invention, but those skilled in the art are come Say it is readily apparent that multiple other can be made in the case of without departing from spirit and scope of the present invention to be changed and modification.Therefore, It is intended to cover to belong to all such changes and modifications in the scope of the invention in claims.

Claims

1. the method being used for rinsing distributor (10), described method includes：

Assembly (399) by described distributor (10) and for rinsing combines, and its offer is used for will be from the first reservoir (50) The first composition (51) and be pumped into minor air cell (130) and premixer from second composition (61) of the second reservoir (60) (150) first stage of at least one in and second stage；

Wherein during the described first stage, described first composition (51) and described second composition (61) substantially simultaneously from Described first reservoir (50) and described second reservoir (60) pump and enter in minor air cell (130) and premixer (150) At least one；

Wherein during described second stage, the one in described first composition (51) and described second composition (61) stops Pumping, the one in simultaneously described first composition (51) and described second composition continues pumping, thus by flush volume (V1) it is pumped at least one in minor air cell (130) and premixer (15)；

The wherein said first stage occurred before described second stage.

2. method according to claim 1, wherein said flush volume (V1) is about 5 microlitres to about 50 microlitres.

3., according to method in any one of the preceding claims wherein, wherein said distributor also includes and described first pump (90) Operate the actuator associating with described second pump (100).

4., according to method in any one of the preceding claims wherein, wherein said distributor includes premixer (150).

5., according to method in any one of the preceding claims wherein, wherein said distributor includes minor air cell (130) and premix Room (150).

6., according to method in any one of the preceding claims wherein, wherein said first composition comprises not to be volatile solvent Carrier and multiple microcapsules, and described second composition comprises volatile solvent.

7. method according to claim 5, wherein said first composition (51) and described second composition (61) are entering Enter described minor air cell (130) unmixed before.

8. the method according to claim 4 or 5, wherein said first composition (51) and described second composition (61) exist Enter described premixer (150) unmixed before.

9. the method according to claim 4 or 5, wherein said premixer (150) include mixed volume, and described distribution Device distributes dispensed volume.

10. method according to claim 9, wherein said mixed volume is for by the stereometer about 1% of described dispensed volume To 75%, preferably from about 2% to about 20%, more preferably from about 4% to about 14%.

11. methods according to claim 9, wherein said dispensed volume is about 30 microlitres to about 300 microlitres, and preferably from about 50 Microlitre is to about 140 microlitres, and more preferably from about 70 microlitres are to about 110 microlitres.

12. according to method in any one of the preceding claims wherein, wherein said first composition (51) and described second group At least one in compound (61) comprises aromatic.

13. according to method in any one of the preceding claims wherein, wherein said first pump (90) and described second pump (100) Displaced volume different.

14. according to method in any one of the preceding claims wherein, and wherein said distributor (10) includes for storing described First reservoir (50) of the first composition (51) and for storing second reservoir (60) of described second composition, described point Orchestration also include with first pump (90) of described first reservoir (50) fluid connection and with described second reservoir (60) liquid Second pump (100) of connection, described first pump (90) and described second pump (100) be respective and in minor air cell and premixer (150) At least one fluid connection；Wherein when each one includes in described distributor, described premixer (150) and described minor air cell With outlet (40), described first pump (90) and described second pump (100) fluid connection.

15. include more than 50% according to method in any one of the preceding claims wherein, wherein said flush volume (V1) Ethanol.