CN106421713A - Traditional Chinese medicine composition for curing diarrhoea - Google Patents

Traditional Chinese medicine composition for curing diarrhoea Download PDF

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CN106421713A
CN106421713A CN201611038723.6A CN201611038723A CN106421713A CN 106421713 A CN106421713 A CN 106421713A CN 201611038723 A CN201611038723 A CN 201611038723A CN 106421713 A CN106421713 A CN 106421713A
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chinese medicine
semen
herba
medicine composition
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张晓燕
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/487Psoralea
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Abstract

The invention discloses a traditional Chinese medicine composition for curing diarrhea. The traditional Chinese medicine composition comprises the following herbs in parts by weight: 20-40 parts of fructus psoraleae, 5-15 parts of myristica fragrans, 5-15 parts of fructus evodiae, 5-15 parts of schisandra chinensis, 30-90 parts of semen coicis, 5-15 parts of chinese lobelia, 10-20 parts of semen plantaginis, 10-30 parts of lotus leaf, 10-30 parts of vernonia patula, 10-20 parts of golden cypress, 5-15 parts of piper longum, 10-30 parts of sticktight, 10-20 parts of cynomorium songaricum, 10-20 parts of forgon euryale seed, 5-15 parts of cinnamon, 3-9 parts of monkshood, 10-30 parts of bighead atractylodes rhizome, 5-15 parts of rhizoma zingiberis, 20-40 parts of codonopsis pilosula, 30-90 parts of astragalus membranaceus, and 5-15 parts of cimicifugae foetidae. The traditional Chinese medicine composition has the effects of removing dampness by means of aromatics, relieving exterior syndrome, expelling cold, tonifying spleen, warming kidney, and stopping diarrhea with astringents, is scientific in compatability, has a remarkable curative effect and a reliable action, and does not have side effects.

Description

The Chinese medicine composition that a kind for the treatment of is had loose bowels
Technical field
The invention belongs to technical field of Chinese medicines is and in particular to a kind of Chinese medicine composition had loose bowels for the treatment of.
Background technology
Have loose bowels also known as diarrhoea, refer to that times of defecation increases, feces are thin, or even as water sample.Diarrhea due to cold pathogen person, has loose bowels thin, has When as water sample, cold type of pain in abdomen, borborygmus;The vexed lack of appetite of gastral cavity, borborygmus of suffering from abdominal pain, rush down rear alleviation of pain, the mostly disease of dyspepsia the intestines and stomach.Equal throughout the year Can occur, but common with season in autumn in summer two, and clinic can be divided into acute diarrhea and chronic diarrhea two class.It is more common in the acute and chronic of western medicine Enteritis, gastrointestinal dysfunction, Anaphylaxis enteritiss, ulcerative colitiss, tuberculosis of intestine etc..
At present, clinical treatment is had loose bowels mainly based on antibiotic therapy, such as:Norfloxacin, Synergic Sulphonamides Compound Tablets, furazolidone The Western medicine such as piece.Although can the of short duration alleviation state of an illness, long-term taking, be also easy to produce drug dependence, and large side effects, take stopgap measures and do not control This.
Content of the invention
Have that drug dependence is strong, cure the symptoms, not the disease to overcome to have loose bowels using antibiotic medicine treatment in prior art Deficiency, the present invention provides the Chinese medicine composition that a kind of compatibility science, evident in efficacy, reliable effect, the treatment having no side effect are had loose bowels.
The present invention solves the technical scheme that adopted of technical problem:The Chinese medicine composition that a kind for the treatment of is had loose bowels, its feature It is:Its raw material of Chinese medicine and weight are:Fructus Psoraleae 20-40 part, Semen Myristicae 5-15 part, Fructus Evodiae 5-15 part, Fructus Schisandrae Chinensis 5-15 part, Semen Coiciss 30-90 part, Herba Lobeliae Chinensis 5-15 part, Semen Plantaginiss 10-20 part, Folium Nelumbinis 10-30 part, Herba Vernoniae Patulae 10-30 part is yellow Cypress 10-20 part, Piper longum 5-15 part, Herba Bidentis Bipinnatae 10-30 part, Herba Cynomorii 10-20 part, Semen Euryaless 10-20 part, Cortex Cinnamomi 5-15 part, Radix Aconiti Lateralis Preparata 3-9 Part, Rhizoma Atractylodis Macrocephalae 10-30 part, Rhizoma Zingiberiss 5-15 part, Radix Codonopsis 20-40 part, Radix Astragali 30-90 part, Rhizoma Cimicifugae 5-15 part.
The preferred technical solution of the present invention is:A kind of Chinese medicine composition that treatment is had loose bowels it is characterised in that:Its raw material of Chinese medicine And weight is:30 parts of Fructus Psoraleae, 10 parts of Semen Myristicae, 10 parts of Fructus Evodiae, 10 parts of Fructus Schisandrae Chinensis, 60 parts of Semen Coiciss, Herba Lobeliae Chinensis 10 parts, 15 parts of Semen Plantaginiss, 20 parts of Folium Nelumbinis, 20 parts of Herba Vernoniae Patulae, 15 parts of Cortex Phellodendri, 10 parts of Piper longum, 20 parts of Herba Bidentis Bipinnatae, 15 parts of Herba Cynomorii, Gorgon euryale Real 15 parts, 10 parts of Cortex Cinnamomi, 6 parts of Radix Aconiti Lateralis Preparata, 20 parts of the Rhizoma Atractylodis Macrocephalae, 10 parts of Rhizoma Zingiberiss, 30 parts of Radix Codonopsis, 60 parts of the Radix Astragali, 10 parts of Rhizoma Cimicifugae.
Have loose bowels because of being invaded by exogenous pathogen, injury due to diet, feelings will is uncomfortable.Main pathogenesis are the wet Shengs of the splenopathy, and transformation and transportation of the spleen and stomach is lacked of proper care, Intestinal separating clear and excreting turbid, conduction function mistake department.Pathological factor is mainly wet, damp being a kind of YIN pathogen, is easily stranded spleen sun.The spleen has the function to transport and transform nutrients, likes dry evil Wet, turbid, conduction is secreted by intestine and small intestine department.If dysfunction of the spleen in transportation, small intestinal is difficult separating clear and excreting turbid, then have loose bowels.Therefore have loose bowels should be with for treatment Removing dampness by means of aromatics, relieving exterior syndrome and dispelling cold, spleen invigorating the kidney warming, stopping diarrhea with astringents is the rule for the treatment of.
In the Chinese medicine composition of the present invention, Fructus Psoraleae bitter in the mouth warm in nature, mend fire from the gater of life with replenishing vital QI with drugs of warm nature spleen soil, to control diarrhea due to kidney-dificiency, be Monarch drug.Semen Myristicae warming middle-JIAO astringing intestine to stop diarrhea, with Psoralen lipid phase 5, both can heat the power that kidney warms up spleen, and can relieving diarrhea with astringents;Fructus Evodiae warming the spleen warms up Stomach is reinforced the kidney astringing intestine to stop diarrhea with dissipating YIN-cold, Fructus Schisandrae Chinensis, and two medicine phases make, and warming the spleen cold expelling, with the power of the puckery antidiarrheal of principal drug assistance temperature, altogether for ministerial drug.Assistant With Radix Astragali invigorating qi and benefiting blood, Radix Codonopsis invigorating the spleen and replenishing QI, Rhizoma Atractylodis Macrocephalae replenishing QI to invigorate the spleen, Rhizoma Cimicifugae benefiting qi and raising yang, four medicine phases make reinforcing body resistance;Semen Coiciss Core, Herba Lobeliae Chinensis, Semen Plantaginiss, Folium Nelumbinis, Herba Vernoniae Patulae five medicine inducing diuresis to remove edema, excreting dampness antidiarrheal;Cortex Phellodendri, Piper longum, Herba Bidentis Bipinnatae three medicine heat clearing away are dry Wet, invigorating the spleen and benefiting QI;Herba Cynomorii, Semen Euryaless two medicine the kidney invigorating and essence nourishing, tonifying spleen and stopping diarrhea;Cortex Cinnamomi warming the kidney to activate YANG, Radix Aconiti Lateralis Preparata warming YANG and invigorating QI, Rhizoma Zingiberiss warming middle-JIAO Cold expelling three medicine warming the spleen, by cold, helps the work(of the monarch and his subjects;Cortex Cinnamomi guiding fire to origin simultaneously, to grow each medicine effect.Finally use Radix Glycyrrhizae coordinating the actions of various ingredients in a prescription, For making medicine.Make a general survey of side entirely and reuse Fructus Psoraleae, spleen astringing intestine to stop diarrhea, treating both the principal and secondary aspects of a disease are warmed up with the kidney warming.
Chinese medicine composition compatibility science provided by the present invention, the Chinese medicine composition of present invention decocting method routinely is produced Medicament is taken.Verify by clinic application, it is evident in efficacy, reliable effect, mild in medicine property and, toxic and side effects, total effective rate do not occur 97%, cure rate reaches 82%.
Specific embodiment
With reference to embodiment, the present invention will be further described.
Embodiment 1
The Chinese medicine composition that a kind for the treatment of is had loose bowels, its raw material of Chinese medicine and weight proportion are:Fructus Psoraleae 30g, Semen Myristicae 10g, Wu Zhu Cornel 10g, Fructus Schisandrae Chinensis 10g, Semen Coiciss 60g, Herba Lobeliae Chinensis 10g, Semen Plantaginiss 15g, Folium Nelumbinis 20g, Herba Vernoniae Patulae 20g, Cortex Phellodendri 15g, Piper longum 10g, Herba Bidentis Bipinnatae 20g, Herba Cynomorii 15g, Semen Euryaless 15g, Cortex Cinnamomi 10g, Radix Aconiti Lateralis Preparata 6g, Rhizoma Atractylodis Macrocephalae 20g, Rhizoma Zingiberiss 10g, Radix Codonopsis 30g, Radix Astragali 60g, Rhizoma Cimicifugae 10g.
Embodiment 2
The Chinese medicine composition that a kind for the treatment of is had loose bowels, its raw material of Chinese medicine and weight proportion are:Fructus Psoraleae 40g, Semen Myristicae 5g, Fructus Evodiae 15g, Fructus Schisandrae Chinensis 5g, Semen Coiciss 90g, Herba Lobeliae Chinensis 5g, Semen Plantaginiss 20g, Folium Nelumbinis 10g, Herba Vernoniae Patulae 30g, Cortex Phellodendri 10g, Piper longum 15g, Herba Bidentis Bipinnatae 10g, Herba Cynomorii 20g, Semen Euryaless 10g, Cortex Cinnamomi 15g, Radix Aconiti Lateralis Preparata 3g, Rhizoma Atractylodis Macrocephalae 30g, Rhizoma Zingiberiss 5g, Radix Codonopsis 40g, Radix Astragali 30g, Rhizoma Cimicifugae 15g.
Embodiment 3
The Chinese medicine composition that a kind for the treatment of is had loose bowels, its raw material of Chinese medicine and weight proportion are:Fructus Psoraleae 20g, Semen Myristicae 15g, Wu Zhu Cornel 5g, Fructus Schisandrae Chinensis 15g, Semen Coiciss 30g, Herba Lobeliae Chinensis 15g, Semen Plantaginiss 10g, Folium Nelumbinis 30g, Herba Vernoniae Patulae 10g, Cortex Phellodendri 20g, Piper longum 5g, Herba Bidentis Bipinnatae 30g, Herba Cynomorii 10g, Semen Euryaless 20g, Cortex Cinnamomi 5g, Radix Aconiti Lateralis Preparata 9g, Rhizoma Atractylodis Macrocephalae 10g, Rhizoma Zingiberiss 15g, Radix Codonopsis 20g, Radix Astragali 90g, rise Numb 5g.
Embodiment 4
The Chinese medicine composition that a kind for the treatment of is had loose bowels, its raw material of Chinese medicine and weight proportion are:Fructus Psoraleae 33g, Semen Myristicae 7g, Fructus Evodiae 13g, Fructus Schisandrae Chinensis 7g, Semen Coiciss 64g, Herba Lobeliae Chinensis 7g, Semen Plantaginiss 18g, Folium Nelumbinis 17g, Herba Vernoniae Patulae 23g, Cortex Phellodendri 12g, Piper longum 13g, Herba Bidentis Bipinnatae 17g, Herba Cynomorii 18g, Semen Euryaless 12g, Cortex Cinnamomi 13g, Radix Aconiti Lateralis Preparata 4g, Rhizoma Atractylodis Macrocephalae 23g, Rhizoma Zingiberiss 7g, Radix Codonopsis 33g, Radix Astragali 55g, Rhizoma Cimicifugae 13g.
Embodiment 5
The Chinese medicine composition that a kind for the treatment of is had loose bowels, its raw material of Chinese medicine and weight proportion are:Fructus Psoraleae 27g, Semen Myristicae 13g, Wu Zhu Cornel 7g, Fructus Schisandrae Chinensis 13g, Semen Coiciss 56g, Herba Lobeliae Chinensis 13g, Semen Plantaginiss 12g, Folium Nelumbinis 23g, Herba Vernoniae Patulae 17g, Cortex Phellodendri 18g, Piper longum 7g, Herba Bidentis Bipinnatae 23g, Herba Cynomorii 12g, Semen Euryaless 17g, Cortex Cinnamomi 7g, Radix Aconiti Lateralis Preparata 9g, Rhizoma Atractylodis Macrocephalae 17g, Rhizoma Zingiberiss 13g, Radix Codonopsis 27g, Radix Astragali 65g, rise Numb 7g.
With reference to the Chinese medicine composition of the present invention, carry out clinical efficacy experiment as follows:
1st, clinical case selects:Select 78 patients that have loose bowels, age 15-70 year.
2nd, clinical symptoms:Soft stools or as water sample, increased frequency, the disease such as can suffer from abdominal pain with abdominal distention;Acute sudden attack of spouting diarrhea onset is dashed forward So, the course of disease is short, can be with diseases such as aversion to cold, heatings;Chronic chronic diarrhea onset is slow, and the course of disease is longer, recurrent exerbation, when light when weight;Drink Food is improper, it is cold and cool to be subject to or emotion changes also can induce and have loose bowels.Above symptom is regarded as having loose bowels.
3rd, experimental technique:Above-mentioned patient is randomly divided into Chinese herbs group and two groups of randomized controlled treatment group, every group of 39 people, its In, Chinese herbs group adopts the Chinese medicine composition that the embodiment of the present invention one provides, its be raw material of Chinese medicine that the present invention is provided by Decoct twice extracting juice about 400ml according to traditional water decoction method, point morning, evening warm twice and take, and one day one, seven days courses for the treatment of.Comparison Treatment group is using oral norfloxacin or furaxone antibiotics Western medicine.
4th, criterion of therapeutical effect:
(1), cure:Stool is normal, and other symptoms disappear, and Clinical Laboratory is normal;
(2), effectively:Times of defecation significantly reduces, and other symptoms are improved;
(3), invalid:Symptom has no improvement.
5th, experimental result:
Chinese herbs group:The 2-6 course for the treatment of of treatment, cures 32, effective 6, invalid 1.Through untoward reaction(ADR)Safety is commented , during treatment, there are not toxic and side effects in valency.
Randomized controlled treatment group:One week treatment, to after three weeks, is cured 33, but drug withdrawal is had 8 Patients on Recurrences for 10-20 days.
By comparing, the Chinese herbs group that the present invention provides treats evident in efficacy, reliable effect of having loose bowels, treating both the principal and secondary aspects of a disease.Right Though fast according to treatment group's treatment speed, drug dependence is strong, is discontinued and easily recurs.
6th, model case:
Case one:Manage certain, man, 37 years old.Lower abdominal pain in the no obvious inducement of patient's readme, and times of defecation is frequent, in water sample, And with diseases such as heating, fear of cold.Oral norfloxacin capsule antibiotics Western medicine, diarrhoea takes a turn for the better, and recurs after drug withdrawal.Take the present invention Chinese medicine composition preparation 2 courses for the treatment of of medicament after, conscious times of defecation significantly reduces, stomachache take a turn for the better;Continue to take 2 treatments Journey, stool is normal, cures.
Case two:Zhang, female, 25 years old.Patient's readme suffers from chronic enteritiss, and stool more than 10 is secondary within one day, sky cold rnning weight, simultaneously With diseases such as abdominal distention, stomachache, lethargy.Period took furaxone, and effect is not notable.Take the Chinese medicine composition of the present invention 3 courses for the treatment of of medicament of thing preparation, times of defecation significantly reduces, and mental attitude takes a turn for the better;Continue after taking 2 courses for the treatment of, stool is normal, other Symptom disappears, and cures.
Raw material of Chinese medicine consumption must be appropriate.Each raw material of Chinese medicine consumption that the present invention is used for clinical experiment is the optimal of the present invention Consumption, it is applied widely.Wherein, Fructus Psoraleae 30g, consumption is big, widely applies based on the kidney warming in side, and to warm up spleen astringing intestine to stop diarrhea, Cure mainly the diarrhea due to kidney-dificiency caused by decline of the fire from the gate of life, fire do not warm up soil;Semen Coiciss 60g, promoting diuresis to eliminate damp pathogen, the spleen strengthening and damp drying, widely apply in side, both oozed Wet and antidiarrheal, also spleen invigorating sun simultaneously, can help the drug effect of the monarch and his subjects;Radix Astragali 60g, Radix Codonopsis 30, two survival doses are big, and mutual reinforcement between phase makes, tonification QI and blood, rises and lifts yang-energy, with reinforcing body resistance.

Claims (2)

1. a kind for the treatment of is had loose bowels Chinese medicine composition it is characterised in that:Its raw material of Chinese medicine and weight are:Fructus Psoraleae 20- 40 parts, Semen Myristicae 5-15 part, Fructus Evodiae 5-15 part, Fructus Schisandrae Chinensis 5-15 part, Semen Coiciss 30-90 part, Herba Lobeliae Chinensis 5-15 part, Semen Plantaginiss 10-20 part, Folium Nelumbinis 10-30 part, Herba Vernoniae Patulae 10-30 part, Cortex Phellodendri 10-20 part, Piper longum 5-15 part, Herba Bidentis Bipinnatae 10-30 part, Herba Cynomorii 10-20 part, Semen Euryaless 10-20 part, Cortex Cinnamomi 5-15 part, Radix Aconiti Lateralis Preparata 3-9 part, Rhizoma Atractylodis Macrocephalae 10-30 part, Rhizoma Zingiberiss 5-15 part, Radix Codonopsis 20-40 part, Radix Astragali 30-90 part, Rhizoma Cimicifugae 5-15 part.
2. a kind for the treatment of according to claim 1 is had loose bowels Chinese medicine composition it is characterised in that:Its raw material of Chinese medicine and weight Part proportioning is:30 parts of Fructus Psoraleae, 10 parts of Semen Myristicae, 10 parts of Fructus Evodiae, 10 parts of Fructus Schisandrae Chinensis, 60 parts of Semen Coiciss, 10 parts of Herba Lobeliae Chinensis, car First sub 15 parts, 20 parts of Folium Nelumbinis, 20 parts of Herba Vernoniae Patulae, 15 parts of Cortex Phellodendri, 10 parts of Piper longum, 20 parts of Herba Bidentis Bipinnatae, 15 parts of Herba Cynomorii, 15 parts of Semen Euryaless, 10 parts of Cortex Cinnamomi, 6 parts of Radix Aconiti Lateralis Preparata, 20 parts of the Rhizoma Atractylodis Macrocephalae, 10 parts of Rhizoma Zingiberiss, 30 parts of Radix Codonopsis, 60 parts of the Radix Astragali, 10 parts of Rhizoma Cimicifugae.
CN201611038723.6A 2016-11-23 2016-11-23 Traditional Chinese medicine composition for curing diarrhoea Pending CN106421713A (en)

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Application publication date: 20170222