CN106421612A - Pharmaceutical composition for resisting helicobator pylori gastric disease - Google Patents
Pharmaceutical composition for resisting helicobator pylori gastric disease Download PDFInfo
- Publication number
- CN106421612A CN106421612A CN201611010957.XA CN201611010957A CN106421612A CN 106421612 A CN106421612 A CN 106421612A CN 201611010957 A CN201611010957 A CN 201611010957A CN 106421612 A CN106421612 A CN 106421612A
- Authority
- CN
- China
- Prior art keywords
- pharmaceutical composition
- radix
- helicobator
- resisting
- helicobacter pylori
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
- 239000008194 pharmaceutical composition Substances 0.000 title claims abstract description 8
- 208000012895 Gastric disease Diseases 0.000 title claims abstract description 7
- 239000003814 drug Substances 0.000 claims abstract description 11
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 7
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims abstract description 5
- 239000002994 raw material Substances 0.000 claims abstract description 3
- 229940037467 helicobacter pylori Drugs 0.000 claims description 12
- 241000590002 Helicobacter pylori Species 0.000 claims description 11
- 241001619461 Poria <basidiomycete fungus> Species 0.000 claims description 5
- 208000018556 stomach disease Diseases 0.000 claims description 5
- 241000628997 Flos Species 0.000 claims description 4
- 239000002893 slag Substances 0.000 claims description 4
- 229940079593 drug Drugs 0.000 claims description 3
- 239000007788 liquid Substances 0.000 claims 1
- 230000000694 effects Effects 0.000 abstract description 18
- 239000000706 filtrate Substances 0.000 abstract description 4
- 231100000331 toxic Toxicity 0.000 abstract description 3
- 230000002588 toxic effect Effects 0.000 abstract description 3
- 238000002360 preparation method Methods 0.000 abstract description 2
- 241000935235 Fritillaria meleagris Species 0.000 abstract 1
- 244000167230 Lonicera japonica Species 0.000 abstract 1
- 235000017617 Lonicera japonica Nutrition 0.000 abstract 1
- GXCLVBGFBYZDAG-UHFFFAOYSA-N N-[2-(1H-indol-3-yl)ethyl]-N-methylprop-2-en-1-amine Chemical compound CN(CCC1=CNC2=C1C=CC=C2)CC=C GXCLVBGFBYZDAG-UHFFFAOYSA-N 0.000 abstract 1
- 244000197580 Poria cocos Species 0.000 abstract 1
- 235000008599 Poria cocos Nutrition 0.000 abstract 1
- 241000292546 Taraxacum mongolicum Species 0.000 abstract 1
- 238000002791 soaking Methods 0.000 abstract 1
- 208000025865 Ulcer Diseases 0.000 description 8
- 231100000397 ulcer Toxicity 0.000 description 8
- 208000007107 Stomach Ulcer Diseases 0.000 description 6
- 201000005917 gastric ulcer Diseases 0.000 description 6
- 239000002253 acid Substances 0.000 description 4
- 210000004877 mucosa Anatomy 0.000 description 4
- 206010000087 Abdominal pain upper Diseases 0.000 description 3
- QTBSBXVTEAMEQO-UHFFFAOYSA-N Acetic acid Chemical compound CC(O)=O QTBSBXVTEAMEQO-UHFFFAOYSA-N 0.000 description 3
- 206010067171 Regurgitation Diseases 0.000 description 3
- 241000589989 Helicobacter Species 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- MWUXSHHQAYIFBG-UHFFFAOYSA-N Nitric oxide Chemical compound O=[N] MWUXSHHQAYIFBG-UHFFFAOYSA-N 0.000 description 2
- 241000700159 Rattus Species 0.000 description 2
- 208000038016 acute inflammation Diseases 0.000 description 2
- 230000006022 acute inflammation Effects 0.000 description 2
- 229960003022 amoxicillin Drugs 0.000 description 2
- LSQZJLSUYDQPKJ-NJBDSQKTSA-N amoxicillin Chemical compound C1([C@@H](N)C(=O)N[C@H]2[C@H]3SC([C@@H](N3C2=O)C(O)=O)(C)C)=CC=C(O)C=C1 LSQZJLSUYDQPKJ-NJBDSQKTSA-N 0.000 description 2
- 208000022531 anorexia Diseases 0.000 description 2
- 230000000845 anti-microbial effect Effects 0.000 description 2
- 230000000740 bleeding effect Effects 0.000 description 2
- 230000001684 chronic effect Effects 0.000 description 2
- 206010061428 decreased appetite Diseases 0.000 description 2
- 238000003745 diagnosis Methods 0.000 description 2
- 230000003628 erosive effect Effects 0.000 description 2
- 239000000284 extract Substances 0.000 description 2
- 235000013305 food Nutrition 0.000 description 2
- 230000002496 gastric effect Effects 0.000 description 2
- 210000001156 gastric mucosa Anatomy 0.000 description 2
- 210000001035 gastrointestinal tract Anatomy 0.000 description 2
- LSQZJLSUYDQPKJ-UHFFFAOYSA-N p-Hydroxyampicillin Natural products O=C1N2C(C(O)=O)C(C)(C)SC2C1NC(=O)C(N)C1=CC=C(O)C=C1 LSQZJLSUYDQPKJ-UHFFFAOYSA-N 0.000 description 2
- 238000010827 pathological analysis Methods 0.000 description 2
- 210000004203 pyloric antrum Anatomy 0.000 description 2
- 229920001817 Agar Polymers 0.000 description 1
- 208000004300 Atrophic Gastritis Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- VTYYLEPIZMXCLO-UHFFFAOYSA-L Calcium carbonate Chemical class [Ca+2].[O-]C([O-])=O VTYYLEPIZMXCLO-UHFFFAOYSA-L 0.000 description 1
- 206010059866 Drug resistance Diseases 0.000 description 1
- 206010015137 Eructation Diseases 0.000 description 1
- LFQSCWFLJHTTHZ-UHFFFAOYSA-N Ethanol Chemical compound CCO LFQSCWFLJHTTHZ-UHFFFAOYSA-N 0.000 description 1
- 208000007882 Gastritis Diseases 0.000 description 1
- 208000036495 Gastritis atrophic Diseases 0.000 description 1
- CEAZRRDELHUEMR-URQXQFDESA-N Gentamicin Chemical compound O1[C@H](C(C)NC)CC[C@@H](N)[C@H]1O[C@H]1[C@H](O)[C@@H](O[C@@H]2[C@@H]([C@@H](NC)[C@@](C)(O)CO2)O)[C@H](N)C[C@@H]1N CEAZRRDELHUEMR-URQXQFDESA-N 0.000 description 1
- 229930182566 Gentamicin Natural products 0.000 description 1
- 206010019375 Helicobacter infections Diseases 0.000 description 1
- 206010022714 Intestinal ulcer Diseases 0.000 description 1
- 206010030113 Oedema Diseases 0.000 description 1
- 208000008469 Peptic Ulcer Diseases 0.000 description 1
- 206010042220 Stress ulcer Diseases 0.000 description 1
- 208000027418 Wounds and injury Diseases 0.000 description 1
- 240000008042 Zea mays Species 0.000 description 1
- 235000005824 Zea mays ssp. parviglumis Nutrition 0.000 description 1
- 235000002017 Zea mays subsp mays Nutrition 0.000 description 1
- 208000019790 abdominal distention Diseases 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 239000008272 agar Substances 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 229940069428 antacid Drugs 0.000 description 1
- 239000003159 antacid agent Substances 0.000 description 1
- 239000003242 anti bacterial agent Substances 0.000 description 1
- 230000001458 anti-acid effect Effects 0.000 description 1
- 230000003110 anti-inflammatory effect Effects 0.000 description 1
- 230000000767 anti-ulcer Effects 0.000 description 1
- 229940088710 antibiotic agent Drugs 0.000 description 1
- 239000003963 antioxidant agent Substances 0.000 description 1
- 230000003078 antioxidant effect Effects 0.000 description 1
- 230000036528 appetite Effects 0.000 description 1
- 235000019789 appetite Nutrition 0.000 description 1
- 230000004596 appetite loss Effects 0.000 description 1
- 239000006286 aqueous extract Substances 0.000 description 1
- 208000027687 belching Diseases 0.000 description 1
- 230000009286 beneficial effect Effects 0.000 description 1
- 230000003115 biocidal effect Effects 0.000 description 1
- 230000015572 biosynthetic process Effects 0.000 description 1
- 229910052797 bismuth Inorganic materials 0.000 description 1
- JCXGWMGPZLAOME-UHFFFAOYSA-N bismuth atom Chemical compound [Bi] JCXGWMGPZLAOME-UHFFFAOYSA-N 0.000 description 1
- 230000017531 blood circulation Effects 0.000 description 1
- 208000016644 chronic atrophic gastritis Diseases 0.000 description 1
- 208000023652 chronic gastritis Diseases 0.000 description 1
- 150000001875 compounds Chemical class 0.000 description 1
- 235000005822 corn Nutrition 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 230000029087 digestion Effects 0.000 description 1
- 238000003113 dilution method Methods 0.000 description 1
- 208000000718 duodenal ulcer Diseases 0.000 description 1
- 235000011389 fruit/vegetable juice Nutrition 0.000 description 1
- 230000035876 healing Effects 0.000 description 1
- 208000015181 infectious disease Diseases 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 239000003112 inhibitor Substances 0.000 description 1
- 230000002401 inhibitory effect Effects 0.000 description 1
- 230000005764 inhibitory process Effects 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 208000019017 loss of appetite Diseases 0.000 description 1
- 235000021266 loss of appetite Nutrition 0.000 description 1
- 210000002751 lymph Anatomy 0.000 description 1
- 235000012054 meals Nutrition 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 208000011906 peptic ulcer disease Diseases 0.000 description 1
- 150000003904 phospholipids Chemical class 0.000 description 1
- 230000001737 promoting effect Effects 0.000 description 1
- 230000001681 protective effect Effects 0.000 description 1
- 239000002423 protozoacide Substances 0.000 description 1
- 238000000746 purification Methods 0.000 description 1
- 210000001187 pylorus Anatomy 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 210000002784 stomach Anatomy 0.000 description 1
- 230000001629 suppression Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 238000003786 synthesis reaction Methods 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 239000000341 volatile oil Substances 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/906—Zingiberaceae (Ginger family)
- A61K36/9064—Amomum, e.g. round cardamom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
- A61K36/076—Poria
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/233—Bupleurum
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
- A61K36/288—Taraxacum (dandelion)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
- A61K36/355—Lonicera (honeysuckle)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/59—Menispermaceae (Moonseed family), e.g. hyperbaena or coralbead
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/718—Coptis (goldthread)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8966—Fritillaria, e.g. checker lily or mission bells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/898—Orchidaceae (Orchid family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
- A61K36/8998—Hordeum (barley)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Alternative & Traditional Medicine (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Medicines Containing Plant Substances (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention relates to the field of medicine formulas, in particular to a pharmaceutical composition for resisting helicobator pylori gastric disease. The pharmaceutical composition is characterized by being prepared by, by weight, 30g of taraxacum mongolicum, 12g of Lonicera japonica, 10g of radix bupleuri, 15g of stir-fried radix paeoniae alba, 10g of radix tinosporae, 15g of poria cocos, 3g of rhizoma coptidis, 15g of rhizoma bletillae, 10g of fructus amomi, 15g of stir-fried malt, 12g of fritillary bulb, 20g of ossa sepiae and 10g of prepared radix glycyrrhizae. A preparation method of the pharmaceutical composition includes: soaking the medicinal raw materials above with water, decocting, and removing dregs to obtain filtrate. The pharmaceutical composition is definite in curative effect, quick in action, high in cure rate, free of toxic and side effects and low in cost.
Description
Technical field
The present invention relates to a kind of Chinese patent medicine preparation, specifically a kind of drug regimen of helicobacter pylori resistant gastropathy
Thing.
Background technology
It is known that helicobacter pylori colonizes in mucosa tissue, the gastric ulcer of 67%-80% and 95% 12 finger
Intestinal ulcer is caused by helicobacter pylori.The universal symptom of chronic gastritiss and digestive tract ulcer patient is:Epigastrium after food
Glutted, uncomfortable or pain, is often accompanied by other ill symptomses, such as belch, abdominal distention, acid regurgitation and loss of appetite etc..Some patients also may be used
Repeated relapsing tormina, a small amount of bleeding of upper digestive tract etc. occur.Helicobacter pylori infection can be cured, general
Therapeutic Principle is based on antibiotic, additional acid inhibitor(Bismuth), common antibiotics amoxicillin, gentamycin, carat
Mycin and amoxicillin etc., but side effect is also more apparent.
Content of the invention
The technical problem to be solved is to overcome the deficiencies in the prior art, providing a kind of anti-H. pylori
The pharmaceutical composition of bacterium gastropathy, determined curative effect, instant effect, cure rate is high, has no toxic side effect, low cost.
The present invention solves above-mentioned technical problem and employed technical scheme comprise that:A kind of medicine group of helicobacter pylori resistant gastropathy
Compound is it is characterised in that be made up of the crude drug of following weight:Herba Taraxaci 30g, Flos Lonicerae 12g, Radix Bupleuri 10g, Radix Paeoniae Alba (parched) 15g,
Radix Tinosporae 10g, Poria 15g, Rhizoma Coptidis 3g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Fructus Amomi 10g, Fructus Hordei Germinatus (parched) 15g, Bulbus Fritillariae Thunbergii 12g, Endoconcha Sepiae 20g, Radix Glycyrrhizae Preparata
10g, above-mentioned raw materials medicine is soaked in water, filtrate of removing slag after decocting to obtain.
The invention has the beneficial effects as follows, determined curative effect, instant effect, cure rate is high, has no toxic side effect, low cost.
Specific embodiment
With reference to embodiment, the invention will be further described:
Embodiment:
Its component(Weight %)Every pair is Herba Taraxaci 30g, Flos Lonicerae 12g, Radix Bupleuri 10g, Radix Paeoniae Alba (parched) 15g, Radix Tinosporae 10g, Poria
15g, Rhizoma Coptidis 3g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Fructus Amomi 10g, Fructus Hordei Germinatus (parched) 15g, Bulbus Fritillariae Thunbergii 12g, Endoconcha Sepiae 20g, Radix Glycyrrhizae Preparata 10g, add water 1000ml
Left and right, soaks 3~4 hours, boils rear slow fire and decocts the filtrate 200ml that removes slag to obtain, medicinal residues add water 200, remove slag after decocting
Filtrate 100ml, there are 300ml about medicine juice, that is, decoction is obtained.Daily 1 dose point is administered orally for 2 times, each (medicine) being taken before meal 150ml
Left and right.
Rhizoma Coptidis antimicrobial and protozoacide effect in side of the present invention, by agar plate dilution method to conventional Chinese medicine 100 taste
Carry out the research of vitro inhibition helicobacter pylori, found that Rhizoma Coptidis etc. have height inhibitory action to helicobacter pylori, can also resist
Ulcer, can suppress gastric injury to be formed.The effect that Radix Tinosporae extract has preventing and treating peptic ulcer and promotes ulcer healing, its
Mechanism may be damaged with antioxidant radical, promotes nitric oxide synthesis, improves gastric mucosa endogenouss PGE2Level thus adjusting
The effect of Mucosal blood flow amount, and anti-Hp infection is relevant.Fructus Amomi volatile oil treats acetic acid ulcer, can make aminohexose and phospholipid
Content significantly raise, so that the hydrophobicity of gastric mucosa is strengthened further, prevent ulcer produce with recurrence.Herba Taraxaci, Radix Glycyrrhizae have suppression
Gastric ulcer effect processed, Herba Taraxaci, Flos Lonicerae, the Radix Paeoniae Alba have resisting pathogenic microbes to act on.Radix Glycyrrhizae has anti-microbial effect, can suppress general
Lead to and Drug resistance Helicobacter pylori.Radix Bupleuri acts on to gastrointestinal, the acidic polysaccharose portion of separation and purification in the hot water extract of Radix Bupleuri
Divide BR-2 coloclysis, alcohol repellency ulcer, harness water logging stress ulcer and rat pylorus ligation ulcer all significantly inhibit to mice
Effect.Poria energy preventing gastric ulcer:Poria aqueous extract, to Oral Administration in Rats, can prevent the generation of slight gastric ulcer, mice is also had
Pre- waterproof attacks the effect of caused stress gastric ulcer.Pseudobulbus Bletillae (Rhizoma Bletillae) has the protective effect to mucosa.Fructus Hordei Germinatus (parched) has the work of promoting digestion and removing stagnation
With.Bulbus Fritillariae Thunbergii has stronger anti-helicobacter pylori activity, antiulcer and analgesic and anti-inflammatory effects.Endoconcha Sepiae has astringing to arrest bleeding, antacid
The effect of pain relieving.
With reference to clinical trial the present invention is made further, describe in detail:
Model case:
King so-and-so, female, 42 years old, vague epigastralgia was uncomfortable, distension after food, belch, acid regurgitation, anorexia.
Gastroscope finding:Antrum is rough, antetheca visible lamellar ulcer, adheres to white fur.
Gastroscope Diagnosis:Gastric ulcer.
Pathological diagnosis:Gastric antrum:Mucosa severe chronic is scorching to be formed with acute inflammation and lymph follicle it is seen that seldom being permitted inflammatory exudation
Thing.Helicobacter pylori.
Give we treatment, one month is a course for the treatment of, after taking a course for the treatment of, vague epigastralgia is uncomfortable to disappear, no acid regurgitation,
Appetite is good, stomach distension, belch after sometimes eating, and after one course for the treatment of of following the service, all cards disappear.Take the 3rd course for the treatment of and consolidate curative effect, half
After year, check gastroscope is normal, Helicobacter pylori-Negative.
Song, man, 50 years old, vague epigastralgia, eat postemphasis, anorexia, belching of gas frequency is made.
Gastroscope finding:Antrum congestion and edema, erosion.
Gastroscope Diagnosis:Non- atrophic gastritis accompanied is rotten to the corn.
Pathological diagnosis:Gastric antrum:Mucosa severe chronic scorching companion acute inflammation and erosion.Helicobacter pylori.
Give we treatment, serve on two courses for the treatment of, remission, interruption takes the 3rd course for the treatment of, after half a year, check gastroscope
Normally, Helicobacter pylori-Negative.
Claims (1)
1. a kind of pharmaceutical composition of helicobacter pylori resistant gastropathy is it is characterised in that be made up of the crude drug of following weight:Pu
Herba Taraxaci 30g, Flos Lonicerae 12g, Radix Bupleuri 10g, Radix Paeoniae Alba (parched) 15g, Radix Tinosporae 10g, Poria 15g, Rhizoma Coptidis 3g, Pseudobulbus Bletillae (Rhizoma Bletillae) 15g, Fructus Amomi 10g,
Fructus Hordei Germinatus (parched) 15g, Bulbus Fritillariae Thunbergii 12g, Endoconcha Sepiae 20g, Radix Glycyrrhizae Preparata 10g, above-mentioned raw materials medicine is soaked in water, and removes slag and must filter after decocting
Liquid.
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201611010957.XA CN106421612A (en) | 2016-11-17 | 2016-11-17 | Pharmaceutical composition for resisting helicobator pylori gastric disease |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201611010957.XA CN106421612A (en) | 2016-11-17 | 2016-11-17 | Pharmaceutical composition for resisting helicobator pylori gastric disease |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106421612A true CN106421612A (en) | 2017-02-22 |
Family
ID=58220904
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201611010957.XA Pending CN106421612A (en) | 2016-11-17 | 2016-11-17 | Pharmaceutical composition for resisting helicobator pylori gastric disease |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106421612A (en) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2022511870A (en) * | 2018-12-06 | 2022-02-01 | グリーン・クロス・ウェルビーイング・コーポレーション | A pharmaceutical composition for the prevention or treatment of Helicobacter pylori infection containing honeysuckle extract. |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102764403A (en) * | 2012-07-18 | 2012-11-07 | 刘晓云 | Traditional Chinese medicine for treating chronic gastritis and gastroduodenal ulcer |
CN103212032A (en) * | 2013-04-11 | 2013-07-24 | 闫忠英 | Traditional Chinese medicine composition for treating gastric diseases |
CN104474441A (en) * | 2014-11-27 | 2015-04-01 | 张雷 | Drug for treating gastropathy |
-
2016
- 2016-11-17 CN CN201611010957.XA patent/CN106421612A/en active Pending
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN102764403A (en) * | 2012-07-18 | 2012-11-07 | 刘晓云 | Traditional Chinese medicine for treating chronic gastritis and gastroduodenal ulcer |
CN103212032A (en) * | 2013-04-11 | 2013-07-24 | 闫忠英 | Traditional Chinese medicine composition for treating gastric diseases |
CN104474441A (en) * | 2014-11-27 | 2015-04-01 | 张雷 | Drug for treating gastropathy |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2022511870A (en) * | 2018-12-06 | 2022-02-01 | グリーン・クロス・ウェルビーイング・コーポレーション | A pharmaceutical composition for the prevention or treatment of Helicobacter pylori infection containing honeysuckle extract. |
EP3892287A4 (en) * | 2018-12-06 | 2022-08-24 | Green Cross Wellbeing Corporation | Lonicera japonica flower water extract-containing pharmaceutical composition for preventing or treating helicobacter pylori infection |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN103182065B (en) | Oral liquid for treating gastric and duodenal ulcer efficiently | |
CN103751739A (en) | Traditional Chinese medicine composition for treating chronic gastritis, application of composition in preparation of medicine for treating chronic gastritis, and preparation method of composition | |
CN104225441A (en) | Traditional Chinese medicine composition for treating stomach trouble and preparation method of granules and capsules of traditional Chinese medicine composition | |
CN115487258A (en) | Traditional Chinese medicine composition for treating gastroesophageal reflux disease, traditional Chinese medicine preparation and preparation method | |
CN103301400B (en) | A kind of Chinese medicine composition and preparation method for the treatment of chronic atrophic gastritis | |
CN107095995B (en) | A pharmaceutical composition for treating gastritis and gastric ulcer, and its preparation method | |
CN101850044B (en) | Medicament for treating peptic ulcer and reflux esophagitis and preparation method thereof | |
CN106421612A (en) | Pharmaceutical composition for resisting helicobator pylori gastric disease | |
CN103055257B (en) | Traditional Chinese medicine for treating chronic gastritis and preparation method thereof | |
CN113876872A (en) | Formula for treating reflux esophagitis | |
CN105833115A (en) | Traditional Chinese medicine for treating precancerous lesions of gastric cancer | |
CN105726787A (en) | Traditional Chinese medicine enema for treating ulcerative colitis and preparing method of traditional Chinese medicine enema | |
CN103768451A (en) | Traditional Chinese medicine for treating chronic pancreatitis | |
CN116159110B (en) | New use of compound traditional Chinese medicine for resolving dampness and clearing spots in treating Behcet disease | |
CN103638280B (en) | For treating the Chinese medicine of reflux esophagitis | |
CN103520620B (en) | A kind of Chinese medicine preparation and preparation method for the treatment of due to weakness of spleen and stomach chronic gastritis | |
CN102846729B (en) | Tibetan medicine for treating gastric ulcer | |
CN105726695A (en) | Medicine composition for treating chronic superficial gastritis | |
CN102784206B (en) | Niweikang and preparation method thereof | |
CN105435202A (en) | Medicinal preparation for treating gastritis and purpose thereof | |
CN105726731A (en) | Traditional Chinese medicine composition as well as preparation method and application thereof | |
CN105148231A (en) | Traditional Chinese medicine used for treating gastric ulcers | |
CN104998189A (en) | Traditional Chinese medicine powder for treating infantile oral ulcer of wind-heat spleen type and preparation method thereof | |
CN104688952A (en) | Traditional Chinese medicine composition for treating damp-heat type bladder cancer and preparing method thereof | |
CN103961632A (en) | Traditional Chinese medicinal composition for treating gastric ulcer and duodenal ulcer |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
SE01 | Entry into force of request for substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170222 |