CN106421349A - Medicine for treating heatstroke and preparation method thereof - Google Patents
Medicine for treating heatstroke and preparation method thereof Download PDFInfo
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- CN106421349A CN106421349A CN201611156568.8A CN201611156568A CN106421349A CN 106421349 A CN106421349 A CN 106421349A CN 201611156568 A CN201611156568 A CN 201611156568A CN 106421349 A CN106421349 A CN 106421349A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/72—Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
- A61K36/725—Ziziphus, e.g. jujube
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/79—Schisandraceae (Schisandra family)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
- A61K36/8968—Ophiopogon (Lilyturf)
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0087—Galenical forms not covered by A61K9/02 - A61K9/7023
- A61K9/0095—Drinks; Beverages; Syrups; Compositions for reconstitution thereof, e.g. powders or tablets to be dispersed in a glass of water; Veterinary drenches
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/53—Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization
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- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
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- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
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Abstract
The invention discloses a medicine for treating heatstroke and a preparation method thereof. The medicine is prepared from the following raw materials in parts by weight: radix ginsengs, radix ophiopogonis, Chinese magnoliavine fruits, fructus jujubae and liquorice roots. The medicine disclosed by the invention has the functions of reinforcing vital energy, relieving depletion and promoting the secretion of saliva or body fluid, clearing away the heart fire and relieving restlessness, benefiting qi for promoting production of fluid, regulating the middle warmer and alleviating pain and nourishing yin and moistening lung, is used for Shengmai powder and has the effects of rapid effect, good curative effect and no recurrence.
Description
Technical field
The present invention relates to a kind of treat medicine of heatstroke and preparation method thereof, belong to the field of Chinese medicines.
Technical background
Heatstroke refers to that long-time is exposed in hot environment or carries out physical exertion in hot environment and causes body body temperature
One group of clinical syndrome caused by regulatory function disorder, is characterized with hyperpyrexia, xerosis cutiss and central nervous system symptom.In
Doctor then thinks warm, summer-heat, gas consumption impairment of YIN and consumption excess of four natures in foods or drugs causing damage of essence, hyperhidrosis Mental fatigue, and fatigue and asthenia is relevant.Due to western medicine side effect
Greatly, therefore there is great demand to the Chinese medicine of effectively treatment heatstroke in people, up to now, it has not been found that with regard to this
Bright relevant report.
Content of the invention
The present inventor have found effectively treatment heatstroke finally according to the research of theory of Chinese medical science and the checking repeatedly of clinical trial
Medicine, so as to complete the present invention.
It is an object of the invention to provide a kind of Chinese medicine composition of effectively treatment heatstroke.
Another object of the present invention just there is provided the preparation method of the Chinese medicine composition.
Medicine of the present invention is to select Radix Ginseng, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Fructus Jujubae, Radix Glycyrrhizae medicine to be combined preparing, by these medicines
Thing combination causes each efficacy of drugs to produce synergism such that it is able to effective SHENGMAI SAN.Wherein from Radix Ginseng, its nature and flavor is because
Sweet micro-sweet, temperature, enter spleen, lung meridian, have strongly invigorating primordial QI, take off admittedly and promote the production of body fluid, the function of calming the nerves, it is deficient to control impairment caused by overstrain, lack of appetite, asthenia, regurgitation
Food is told, lingering diarrhea of defecating, empty cough with asthma promotees, spontaneous perspiration sudden collapse, palpitation with fear, forgetful, dizziness and headache, sexual impotence, and frequent micturition is quenched one's thirst, woman uterine bleeding, little
Youngster's intermittent infantile convulsion and prolonged deficiency be not multiple, the disease of all qi-blood-body fluid deficiencies.From being because its property sweet and slightly bitter taste Radix Ophiopogonis, tremble with fear, enter lung, stomach,
Heart channel, has a nourishing YIN and moistening the lung, relieving restlessness that clears away heart-fire, and the function of reinforcing stomach reg fluid controls dryness of the lung dry cough, spits blood, spitting of blood, consumptive lung disease, lung abscess, and asthenia is tired of
Heat, clear thirsty, calentura Tianjin is hindered, dry mouth and throat, constipation.Its nature and flavor acid is because from Fructus Schisandrae Chinensis, warm, enter lung, kidney channel, astringe the lung,
Nourishing kidney, promotes the production of body fluid, receipts antiperspirant, and the function of arresting seminal emission is controlled the deficiency of the lung and breathed with cough, and xerostomia is made yearningly, spontaneous perspiration, night sweat, impairment caused by overstrain weakness and emaciation, emission, long
Rush down chronic dysentery.It is because that its nature and flavor is sweet from Fructus Jujubae, temperature, enter spleen, stomach, have a spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid, adjust battalion to defend, solve poison of drug
Function, control insufficiency of stomach lack of appetite, the weak loose stool of spleen, qi-blood-body fluid deficiency, disharmony of nutrient QI with defensive QI, severe palpitation, woman hysteria.From Radix Glycyrrhizae it is
Because its nature and flavor is sweet, puts down, enter spleen, stomach, lung meridian, have and middle emergency, lung moistening, removing toxic substances, the function of coordinating the actions of various ingredients in a prescription, use is processed, controls taste
Weakness, lack of appetite, loose stool of suffering from abdominal pain, overstrain generates heat, and consumptive lung disease is coughed, cardiopalmus, shies;Raw use, controls laryngopharynx swelling and pain, peptic ulcer, carbuncle
Cellulitis skin infection, solution poison of drug and alimentary toxicosis.
Specific embodiment
The drug dose of instant component is also that inventor is drawn through groping in a large number to summarize, and the consumption of each component is following heavy
All there is in the range of amount preferable curative effect:
5-15 gram of Radix Ginseng, 15-25 gram of Radix Ophiopogonis, 5-15 gram of Fructus Schisandrae Chinensis, 5-15 gram of Fructus Jujubae, 5-15 gram of Radix Glycyrrhizae.
Preferably:
10 grams of Radix Ginseng, 20 grams of Radix Ophiopogonis, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Fructus Jujubae, 10 grams of Radix Glycyrrhizae.
The preparation method of medicine of the present invention is as follows
First, get the raw materials ready
1st, Radix Ginseng:Except removing LU, cutting;
2nd, Radix Ophiopogonis:Net impurity is picked, is soaked in water, pull out, after running through, pump the heart, then clean and dry;
3rd, Fructus Schisandrae Chinensis:Grey bits are weeded out, impurity is removed, put in food steamer and steam thoroughly, taking-up is dried;
4th, Fructus Jujubae:Net impurity is picked, is dried;
5th, Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant saturating when, pull out, run through, section, dry.
2nd, prepare
1st, the Radix Ginseng after processing, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Fructus Jujubae, Radix Glycyrrhizae are put in decocting container, add water 6 times amount for the first time, soak
After 100 minutes, fry by intense fire to boil and rise, then with being cooked by slow fire 20 minutes, first time decoction liquor is filtered to obtain, first time decoction liquor is fallen
Enter in container;
2nd, the medicinal residues of filtration are added 4 times amount, boils by intense fire, then with being cooked by slow fire 10 minutes, filter to obtain second decoction liquor;
3rd, will decoction liquor mixing and stirring twice, be divided into 2 doses and take.
In prescription, Radix Ginseng has strongly invigorating primordial QI, Gu de- promote the production of body fluid, the function of calming the nerves is monarch drug;Fructus Schisandrae Chinensis are astringed the lung, nourishing kidney, promote the production of body fluid,
Receive antiperspirant, arresting seminal emission;There is nourishing YIN and moistening the lung a Radix Ophiopogonis, relieving restlessness that clears away heart-fire, the function of reinforcing stomach reg fluid, the two is that ministerial drug, three taste medicines play benefit jointly
Vigour, Gu de- promote the production of body fluid, nourishing YIN and moistening the lung of calming the nerves, relieving restlessness that clears away heart-fire, and the effect of nourishing kidney, treatment heatstroke effect is comprehensive, and with strongly invigorating primordial QI,
Promote the production of body fluid Gu de-, relieving restlessness that clears away heart-fire, calm the nerves based on can effect a permanent cure;Fructus Jujubae has a spleen reinforcing stomach function regulating, supplementing QI for promoting the production of body fluid, adjusts battalion to defend, solves the function of poison of drug
For adjuvant drug;Radix Glycyrrhizae has and middle emergency, lung moistening, removing toxic substances, and the function of coordinating the actions of various ingredients in a prescription, for making medicine, is to take stopgap measures with adjuvant drug Fructus Jujubae.
Medicine of the present invention has strongly invigorating primordial QI, Gu de- promote the production of body fluid, relieving restlessness that clears away heart-fire, supplementing QI for promoting the production of body fluid, and middle emergency, nourishing YIN and moistening the lung
Function, for treating warm, summer-heat, gas consumption impairment of YIN, short treating period, instant effect, non-relapse after healing.
Specific embodiment:
The beneficial effect of medicine of the present invention is expanded on further below by way of test example, these test examples include medicine of the present invention
The animal toxicity test report of thing and clinical observation on the therapeutic effect data.
The animal toxicity test report of [test example 1] medicine of the present invention:
Take rabbit 30, male and female dual-purpose, 2.0 2.5kg of body weight, points two groups, per group 15, one of which is overdose test
Group, another group is normal amount test group.Super quantity group is 20ml/kg, and normal amount is that 10ml/kg, administering mode is given for administration by gavage
Medicine, twice daily, serve on 7 days, the reaction of observation administration daily, as a result shows that two groups of rabbit activities, diet are normal, and medicine is no bad
Toxic and side effects.
The clinical observation on the therapeutic effect of [test example 2] medicine of the present invention
1st, physical data
Accept heatstroke out-patient totally 27 for medical treatment.
2nd, diagnostic criteria
Classical symptom is thirsty, inappetence, headache, giddy, hyperhidrosis, tired, weak, nausea and vomiting, cardiopalmus, face extra dry red wine
Or pale, attention laxes, exercise not harmony, and body temperature is normal or rises high symptom.
3rd, Therapeutic Method
From above-mentioned medicament, take to patient, 1 dose is each taken, early daily, evening respectively takes 1 time, continuously takes 3 days.
4th, efficacy assessment standard
Effective:Heatstroke symptom disappears, and body constitution recovers normal, recovery from illness;
Take a turn for the better:Patient's hyperhidrosis, tired, weak, the symptom mitigation of dry throat and mouth, warm, summer-heat symptom are clearly better, and body constitution is progressively
Recover;
Invalid:Improvement standard person is not reached.
5th, therapeutic outcome(See the table below)
In above-mentioned treatment, with Drug therapy heatstroke patient of the present invention 27, as a result effective 20, obvious effective rate is 74.07%, good
Turn 6, improvement rate is 22.23%, invalid 1, total effective rate is 96.3%.
Claims (3)
1. a kind of medicine for treating heatstroke, it is characterised in that:It is made up of the crude drug in following weight range:
5-15 gram of Radix Ginseng, 15-25 gram of Radix Ophiopogonis, 5-15 gram of Fructus Schisandrae Chinensis, 5-15 gram of Fructus Jujubae, 5-15 gram of Radix Glycyrrhizae.
2. medicine according to claim 1, the consumption of wherein each crude drug is:
10 grams of Radix Ginseng, 20 grams of Radix Ophiopogonis, 10 grams of Fructus Schisandrae Chinensis, 10 grams of Fructus Jujubae, 10 grams of Radix Glycyrrhizae.
3. the preparation method of medicine according to claim 1 or claim 2, it comprises the following steps:
(One)Get the raw materials ready
(1)Radix Ginseng:Except removing LU, cutting;
(2)Radix Ophiopogonis:Net impurity is picked, is soaked in water, pull out, after running through, pump the heart, then clean and dry;
(3)Fructus Schisandrae Chinensis:Grey bits are weeded out, impurity is removed, put in food steamer and steam thoroughly, taking-up is dried;
(4)Fructus Jujubae:Net impurity is picked, is dried;
(5)Radix Glycyrrhizae:Pick impurity, clean, be soaked in water to eighty per cant saturating when, pull out, run through, section, dry;
(Two)Prepare
(1)Radix Ginseng after processing, Radix Ophiopogonis, Fructus Schisandrae Chinensis, Fructus Jujubae, Radix Glycyrrhizae are put in decocting container, add water 6 times amount, soak 100 points
Zhong Hou, fries by intense fire to boil and rises, then with being cooked by slow fire 20 minutes, filters to obtain first time decoction liquor, first time decoction liquor is poured into appearance
In device;
(2)The medicinal residues of filtration are added water 4 times amount, is boiled by intense fire, then with being cooked by slow fire 10 minutes, filter to obtain second decoction liquor;
(3)Decoction liquor mixing and stirring twice is incited somebody to action, is divided into 2 doses and takes.
Priority Applications (1)
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CN201611156568.8A CN106421349A (en) | 2016-12-15 | 2016-12-15 | Medicine for treating heatstroke and preparation method thereof |
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CN201611156568.8A CN106421349A (en) | 2016-12-15 | 2016-12-15 | Medicine for treating heatstroke and preparation method thereof |
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Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110464008A (en) * | 2018-05-10 | 2019-11-19 | 无限极(中国)有限公司 | It is a kind of to have effects that depressurize Chinese medicine composition of relieving restlessness and preparation method thereof and purposes |
CN115779060A (en) * | 2022-11-24 | 2023-03-14 | 山西省针灸研究所(山西中医药大学附属针灸推拿医院、山西省针灸医院) | Enteral nutrient solution |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101632786A (en) * | 2009-05-31 | 2010-01-27 | 宫怀恒 | Medicine for treating coma class heatstroke |
CN103386087A (en) * | 2013-07-23 | 2013-11-13 | 肖振锋 | Medicine used for treating abdominal distension and preparation method thereof |
CN104013791A (en) * | 2014-05-28 | 2014-09-03 | 王庚禹 | Extractive for preparing pulse-activating injection |
-
2016
- 2016-12-15 CN CN201611156568.8A patent/CN106421349A/en not_active Withdrawn
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101632786A (en) * | 2009-05-31 | 2010-01-27 | 宫怀恒 | Medicine for treating coma class heatstroke |
CN103386087A (en) * | 2013-07-23 | 2013-11-13 | 肖振锋 | Medicine used for treating abdominal distension and preparation method thereof |
CN104013791A (en) * | 2014-05-28 | 2014-09-03 | 王庚禹 | Extractive for preparing pulse-activating injection |
Non-Patent Citations (1)
Title |
---|
林盛进著: "《经方直解》", 31 May 2016, 中国中医药出版社 * |
Cited By (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN110464008A (en) * | 2018-05-10 | 2019-11-19 | 无限极(中国)有限公司 | It is a kind of to have effects that depressurize Chinese medicine composition of relieving restlessness and preparation method thereof and purposes |
CN115779060A (en) * | 2022-11-24 | 2023-03-14 | 山西省针灸研究所(山西中医药大学附属针灸推拿医院、山西省针灸医院) | Enteral nutrient solution |
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Application publication date: 20170222 |