CN106421341B - A kind of Chinese medicine composition and its preparation method and application for treating acute bronchitis - Google Patents
A kind of Chinese medicine composition and its preparation method and application for treating acute bronchitis Download PDFInfo
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- A61K36/18—Magnoliophyta (angiosperms)
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- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
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- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
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Abstract
The invention discloses a kind of Chinese medicine composition and its preparation method and application for treating acute bronchitis, the Chinese medicine composition of the treatment acute bronchitis includes: 14~18 parts of Rumex madaio, 2~6 parts of radix cyathulae, 2~6 parts of radix gentianae, 1~3 part of Radix Glycyrrhizae, 1~3 part of Radix Ophiopogonis and 1~3 part of dandelion according to mass fraction.The present invention passes through Rumex madaio, radix cyathulae, radix gentianae, Radix Glycyrrhizae, the reasonable compatibility of Radix Ophiopogonis and each traditional Chinese medicinal components of dandelion, with tonifying Qi eliminating evil, eliminating heat from the lung, blood circulation promoting and dispersing pathogen accumulation effect, and material is easy to obtain, preparation method is simple, low cost, has no toxic side effect, it is significant in efficacy for acute bronchitis.
Description
Technical field
The present invention relates to technical field of traditional Chinese medicines, and in particular to a kind of Chinese medicine composition for treating acute bronchitis and its system
Preparation Method and application.
Background technique
Acute bronchitis is respiratory tract common disease, frequently-occurring disease, often secondary to the infection of the upper respiratory tract after, early stage
Upper respiratory tract infection symptoms are often appeared as, patient usually there are the clinical manifestations such as nasal obstruction, watery nasal discharge, pharyngalgia and hoarseness.Entirely
Body symptom is more slight, and sometimes out of strength with low-heat, chilly, the whole body, conscious bottleneck throat is itched, and irritant cough and breastbone
Pain afterwards.Early stage amount of expectoration is few, but sputum is not easy expectoration, and sputum can be switched to mucus purulence by mucus after 2~3 days.
China treats acute bronchitis and has accumulated experience abundant as Chinese Traditional Medicine big country, traditional in recent years
Chinese medicine discloses multiple formulations, and the Chinese medicine preparation for treating acute bronchitis is different, and therapeutic effect is also not quite similar, respectively
There is feature.
The Chinese patent literature of Publication No. CN105434943A discloses a kind of Chinese medicine composition for treating bronchitis,
The Chinese medicine composition of the patent includes that Radix Paeoniae Alba, pueraria lobata, cat grab grass, Radix Notoginseng, reed root, radix dactylicapni, Rumex madaio, the root of three-nerved spicebush and oxtongue,
It is taken with decocting decoction of medicinal ingredients, portion decoction twice, the disadvantage is that not having the effect of eliminating the phlegm, does not prove its pharmacological action yet.
The Chinese patent literature of Publication No. CN104367689A discloses a kind of composition for treating acute bronchitis
Chinese medicine, the patent are made of Chinese ephedra, semen armeniacae amarae, pheretima, cordate houttuynia, have relieving exterior syndrome and dispelling cold, clearing heat and detoxicating, relieving cough and reducing sputum function
Effect, but fail further to prove its clinical effectiveness.
The treatment of acute bronchitis is mainly taken based on antibiotic anti-inflammatory at present, but old complaint cannot be eliminated, is made
At recurrent exerbation, pulmonary emphysema, threat to life are developed into.And the Chinese medicine of existing treatment acute bronchitis can not be anxious in effective treatment
Property bronchitis while, treat hoarseness the problem of.
Summary of the invention
The purpose of the present invention is to provide it is a kind of it is quick, to cure the period short, there is tonifying Qi eliminating evil, eliminating heat from the lung, promoting blood circulation
The Chinese medicine composition of dissipating bind, for treating acute bronchitis.
To achieve the above object, first aspect present invention provides a kind of Chinese medicine composition for treating acute bronchitis.
Specifically, the Chinese medicine composition includes: 14~18 parts of Rumex madaio, 2~6 parts of radix cyathulae, radix gentianae 2~6 according to mass fraction
Part, 1~3 part of Radix Glycyrrhizae, 1~3 part of Radix Ophiopogonis and 1~3 part of dandelion.
Preferably, the Chinese medicine composition includes: 15~17 parts of Rumex madaio, 3~5 parts of radix cyathulae, dragon according to mass fraction
3~5 parts of gallbladder grass, 2~3 parts of Radix Glycyrrhizae, 2~3 parts of Radix Ophiopogonis and 2~3 parts of dandelion.
Preferably, the Chinese medicine composition according to mass fraction include: 16 parts of Rumex madaio, 4 parts of radix cyathulae, 4 parts of radix gentianae,
2 parts of Radix Glycyrrhizae, 2 parts of Radix Ophiopogonis and 2 parts of dandelion.
Preferably, the Chinese medicine composition is tablet, capsule, granule, pill, powder or paste, solution.
Second aspect of the present invention provides a kind of Chinese medicine composition preparation method for treating acute bronchitis.Specifically,
It the described method comprises the following steps:
One, it by Rumex madaio, radix cyathulae, radix gentianae, Radix Glycyrrhizae, Radix Ophiopogonis and dandelion, is uniformly mixed, is mixed after pulverizing and sieving
Close medicinal powder；
Two, mixed powder obtained in step 1 is put into decoction vessel, the water that 6~10 times of quality of mixed powder are added decocts
1~1.5h obtains decoction liquor；
Three, decoction liquor obtained in step 2 is concentrated after receiving juice and is dried to obtain powder, obtain treatment acute bronchus
Scorching Chinese medicine composition.
Preferably, the aperture being sieved in the step 1 is 150~300 mesh.
Preferably, the water in the step 2 is distilled water or deionized water.
Preferably, the number decocted in the step 2 is 2~3 times.
Third aspect present invention provides a kind of application of Chinese medicine composition for treating acute bronchitis.Specifically, institute
Chinese medicine composition is stated for treating hoarseness caused by lung heat acute bronchitis and acute bronchitis.
The present invention has the advantage that
1, the present invention is advanced using the modern times using Rumex madaio, radix cyathulae, radix gentianae, Radix Glycyrrhizae, Radix Ophiopogonis and dandelion as raw material
Medical pharmaceutical technology be made, have material be easy to obtain, preparation method is simple, low cost, have no toxic side effect.
2, the present invention is by the reasonable compatibilities of each traditional Chinese medicinal components, with tonifying Qi eliminating evil, eliminating heat from the lung, and blood circulation promoting and dispersing pathogen accumulation effect,
It is obvious to hoarseness effect caused by treatment lung heat acute bronchitis and acute bronchitis.
3, Chinese medicine composition of the invention is quick, short treating period, anxious caused by can effectively treating in a short time because of lung heat
Property bronchitis, it is significant in efficacy.
The pharmacological property and pharmacology of Chinese herbal medicine selected by the present invention are as follows:
Rumex madaio: bitter is trembled with fear, slightly poisonous.Major function: clearing heat and detoxicating, hemostasis, dissolving stasis, defaecation, Li Shui, cooling blood and hemostasis,
Desinsection is antipruritic.For lung abscess, hemoptysis of pulmonary tuberculosis, bleeding from five sense organs or subcutaneous tissue, Japanese Type-B encephalitis, acute hepatitis, chronic hepatitis, constipation.Modern pharmacology
The study found that Rumex madaio has antibacterial, hemostasis, antitumor, anti-oxidant, eliminating the phlegm, cough-relieving, a pharmacological actions such as relieving asthma, activity compared with
By force, it can be used for treating a variety of diseases such as skin disease, haemorrhage, traumatic injury, purpura, parotitis.
Radix cyathulae: sweet in flavor, slight bitter, it is mild-natured.Major function: blood circulation, nourishing liver and kidney, strengthening the bones and muscles, inducing diuresis for treating strangurtia.For controlling
Treat the gynaecological diseases such as menostasis, dysmenorrhea, irregular menstruation, the postpartum abdominal pain of stagnation of blood stasis, traumatic injury, soreness of waist and knee joint, the lower limb of kidney deficiency
It is powerless, hematuria, difficult urination, the diseases such as Urethra astringent pain and burning hot scorching caused headache, dizziness, haematemesis, bleeding from five sense organs or subcutaneous tissue.Modern pharmacology
The study found that changing in radix cyathulae containing a variety of natural organic matters, platelet aggregation-againsts such as polysaccharide, ketosteroid, saponin(e, ferulic acids
Kind microcirculation, the effect for promoting protein synthesis, delaying senescence.
Radix gentianae: bitter is puckery, Great Cold, nontoxic.Major function: heat-clearing and damp-drying drug, purging the liver of pathogenic fire gallbladder fire.For jaundice with damp-heat pathogen, swelling of vulva
Pruritus vulvae, leukorrhagia, Qiang Zhong, eczema itch, urine leaching pain, hot eyes is deaf, hypochondriac pain, bitter taste, convulsion.Modern pharmacological research hair
Existing, radix gentianae contains gentiamarin, Swertiamarin, trifloroside, amarogentin, amaroswerin, gentioflavine, erythricine, gentianae macrophyllae second
Element, gentianol, gentianose etc., to Pseudomonas aeruginosa, proteus, typhoid bacillus, shigella dysenteriae, staphylococcus aureus etc.
There is different degrees of inhibiting effect, and serum bilirubin level can be effectively reduced.
Radix Glycyrrhizae: sweet in flavor, mild-natured.Major function: invigorate the spleen and benefit qi, clearing heat and detoxicating, expelling phlegm and arresting coughing, relieving spasm to stop pain, coordinating the drug actions of a prescription.
For weakness of the spleen and the stomach, fatigue and weakness, shortness of breath and palpitation, coughing with a lot of sputum, stomach duct and abdomen, four limbs contraction, carbuncle sore tumefacting virus, alleviation drug poison
It is property, strong.Modern pharmacological research discovery, Radix Glycyrrhizae contain there are many chemical component, and main component has glycyrrhizic acid, liquiritin etc., has
Anti-inflammatory and resistance state reflection function, can also extend epithelial cell life, have to chronic adrenocortical hypofunction good
Good effect.
Radix Ophiopogonis: sweet in flavor, slight bitter, it is slightly cold.Major function: Yin nourishing and lung moistening, reinforcing stomach reg fluid, relieving restlessness and restlessness.For dryness of the lung dry cough,
The diseases such as cough for deficiency of Yin consumptive disease, larynx numbness pharyngalgia, injury thirst, Heat Diabetes, vexed insomnia, dry constipation of intestines.Modern pharmacological research discovery, wheat
Winter mainly contains dwarf lilyturf glycosides, steroid saponin, alkaloid, sitosterol, glucose, amino acid, vitamin etc., has antifatigue, clear
Except free radical, improve cellular immune function and hypoglycemic effect.In addition, there is calmness in Radix Ophiopogonis, hypnosis, resists myocardial ischemia, resists
Arrhythmia cordis, it is antitumor the effects of, especially to promote senior health and fitness have effects that various aspects.
Dandelion: sweet in flavor, slight bitter is trembled with fear.Major function: having diuresis, laxative, removing jaundice subcutaneous ulcer, cholagogue and other effects.For controlling heat
Poison, cold, fever, tonsillitis, acute laryngopharyngitis, acute bronchus is refreshing, filariasis, adenolymphitis, wind-fire red eye, gastritis, liver
Inflammation, osteomyelitis.Modern pharmacological research discovery, it is a variety of that dandelion contains taraxol, taraxacin, choline, organic acid, synanthrin etc.
Health-nutrition ingredient has the function of antibacterial, antitumor, cholagogue.
Specific embodiment
The following examples are used to illustrate the present invention, but are not intended to limit the scope of the present invention..
Embodiment 1
The preparation method that the Chinese medicine composition of acute bronchitis is treated in the present embodiment, sequentially includes the following steps:
One, it by Rumex madaio, radix cyathulae, radix gentianae, Radix Glycyrrhizae, Radix Ophiopogonis and dandelion, is uniformly mixed after crushed 240 meshes,
Obtain mixed powder；
Two, mixed powder obtained in step 1 is put into decoction vessel, the distilled water of 9 times of quality of mixed powder is added or gone
Ionized water decocts 2 times, and each 1h obtains decoction liquor；
Three, decoction liquor obtained in step 2 is concentrated after receiving juice and is dried to obtain powder, obtain treatment acute bronchus
Scorching Chinese medicine composition.
Embodiment 2
The preparation method that the Chinese medicine composition of acute bronchitis is treated in the present embodiment, sequentially includes the following steps:
One, it by Rumex madaio, radix cyathulae, radix gentianae, Radix Glycyrrhizae, Radix Ophiopogonis and dandelion, is uniformly mixed after crushed 150 meshes,
Obtain mixed powder；
Two, mixed powder obtained in step 1 is put into decoction vessel, the distilled water of 6 times of quality of mixed powder is added or gone
Ionized water decocts 3 times, and each 1.2h obtains decoction liquor；
Three, decoction liquor obtained in step 2 is concentrated after receiving juice and is dried to obtain powder, obtain treatment acute bronchus
Scorching Chinese medicine composition.
Embodiment 3
The preparation method that the Chinese medicine composition of acute bronchitis is treated in the present embodiment, sequentially includes the following steps:
One, it by Rumex madaio, radix cyathulae, radix gentianae, Radix Glycyrrhizae, Radix Ophiopogonis and dandelion, is uniformly mixed after crushed 200 meshes,
Obtain mixed powder；
Two, mixed powder obtained in step 1 is put into decoction vessel, be added 10 times of quality of mixed powder distilled water or
Deionized water decocts 2 times, and each 1.4h obtains decoction liquor；
Three, decoction liquor obtained in step 2 is concentrated after receiving juice and is dried to obtain powder, obtain treatment acute bronchus
Scorching Chinese medicine composition.
Embodiment 4
The preparation method that the Chinese medicine composition of acute bronchitis is treated in the present embodiment, sequentially includes the following steps:
One, it by Rumex madaio, radix cyathulae, radix gentianae, Radix Glycyrrhizae, Radix Ophiopogonis and dandelion, is uniformly mixed after crushed 180 meshes,
Obtain mixed powder；
Two, mixed powder obtained in step 1 is put into decoction vessel, the distilled water of 8 times of quality of mixed powder is added or gone
Ionized water decocts 2 times, and each 1h obtains decoction liquor；
Three, decoction liquor obtained in step 2 is concentrated after receiving juice and is dried to obtain powder, obtain treatment acute bronchus
Scorching Chinese medicine composition.
Embodiment 5
The preparation method that the Chinese medicine composition of acute bronchitis is treated in the present embodiment, sequentially includes the following steps:
One, by Rumex madaio, radix cyathulae, radix gentianae, Radix Glycyrrhizae, Radix Ophiopogonis and dandelion, it crushed, be uniformly mixed after 300 meshes,
Obtain mixed powder；
Two, mixed powder obtained in step 1 is put into decoction vessel, the distilled water of 7 times of quality of mixed powder is added or gone
Ionized water decocts 3 times, and each 1.5h obtains decoction liquor；
Three, decoction liquor obtained in step 2 is concentrated after receiving juice and is dried to obtain powder, obtain treatment acute bronchus
Scorching Chinese medicine composition.
Single medicinal material in composition described above, especially ministerial drug and adjutant can also be had in identical pharmacological property by appropriate
Medicine replacement, its drug effect of replaced Chinese materia medica preparation are constant.Above-described embodiment, can be weighed by score ratio raw material be made tablet,
Capsule, granule, pill, powder or paste, solution.
Chinese medicine composition effect for the treatment of acute bronchitis of the invention is confirmed in clinical application, is treated
Effect is as follows:
Acute bronchitis symptom: nasal obstruction, discomfort, shiver with cold, low-heat, back and myalgia and sore-throat, sound are neighed
Mute, violent cough.
Significant in efficacy: the above clinical symptoms all disappear, without recurrence in 1 year；
Effective: the above clinical symptoms all disappear, and hoarseness symptom disappears；
Improve: the above clinical symptoms partial disappearance, hoarseness symptom are substantially reduced；
It is invalid: to have no and be clearly better.
150 acute bronchitis patients are chosen, the treatment being prepared respectively using the method for Examples 1 to 5 is acute
The Chinese medicine composition of bronchitis, wherein 80 people's moderate patient of patients with mild, 40 people, 30 people of severe patient.
150 acute bronchitis patients are taken to the particle of the Chinese medicine composition for the treatment of acute bronchitis of the invention
Agent, every 10 grams of packet, patient per takes 10~15 grams, three times per day.One week as a treatment course, and uses 1 year after this product healing
Recovery from illness patient afterwards pays a return visit, and counts recurrence rate.
The granule of the Chinese medicine composition for the treatment acute bronchitis that 1 Examples 1 to 5 of table is prepared is to 150 urgency
The treatment condition of property bronochitic
From table 1 it follows that acute bronchitis patient uses the acute branch gas for the treatment of that Examples 1 to 5 is prepared
The granule of the Chinese medicine composition of Guan Yan, first course for the treatment of rate significant in efficacy is 40~50%, and acute bronchitis patient
It is gradually increased with using the increase of the course for the treatment of thoroughly to cure patient, continuously efficient after taking two courses for the treatment of up to 97.3%, it is thorough
It is 0% that bottom, which cures recurrence rate in patient 1 year, the far super existing product of therapeutic effect.
Typical case is as follows:
1, Pan, female 42 years old, teacher, affection of exogenous wind-heat caused acute bronchitis, and causes hoarseness, took two days
Hoarseness is eliminated afterwards, and after taking a course for the treatment of, illness is cured.
2, Wu, female 31 years old, scientific and technical personnel caused acute bronchitis by affection of exogenous wind-heat, cure after taking two courses for the treatment of.
3, poplar, female 29 years old, peasant, affection of exogenous wind-heat causes acute bronchitis, and causes hoarseness, takes three days
Hoarseness is eliminated afterwards, is taken two courses for the treatment of of Chinese medicine and is cured.
Although above having used general explanation and specific embodiment, the present invention is described in detail, at this
On the basis of invention, it can be made some modifications or improvements, this will be apparent to those skilled in the art.Therefore,
These modifications or improvements without departing from theon the basis of the spirit of the present invention are fallen within the scope of the claimed invention.
Claims (8)
1. a kind of Chinese medicine composition for treating acute bronchitis, it is characterised in that: the Chinese medicine composition is according to mass fraction
It consists of the following compositions: 14~18 parts of Rumex madaio, 2~6 parts of radix cyathulae, 2~6 parts of radix gentianae, 1~3 part of Radix Glycyrrhizae, 1~3 part of Radix Ophiopogonis
With 1~3 part of dandelion.
2. Chinese medicine composition according to claim 1, it is characterised in that: the Chinese medicine composition according to mass fraction by with
It is lower at being grouped as: 15~17 parts of Rumex madaio, 3~5 parts of radix cyathulae, 3~5 parts of radix gentianae, 2~3 parts of Radix Glycyrrhizae, 2~3 parts of Radix Ophiopogonis and Pu
2~3 parts of public English.
3. Chinese medicine composition according to claim 1, it is characterised in that: the Chinese medicine composition according to mass fraction by with
It is lower at being grouped as: 16 parts of Rumex madaio, 4 parts of radix cyathulae, 4 parts of radix gentianae, 2 parts of Radix Glycyrrhizae, 2 parts of Radix Ophiopogonis and 2 parts of dandelion.
4. Chinese medicine composition according to any one of claim 1-3, it is characterised in that: the Chinese medicine composition is piece
Agent, capsule, granule, pill, powder or paste, solution.
5. a kind of preparation method for the Chinese medicine composition for treating acute bronchitis, which is characterized in that the Chinese medicine composition is
The described in any item Chinese medicine compositions of claim 1-3, the described method comprises the following steps:
One, it by Rumex madaio, radix cyathulae, radix gentianae, Radix Glycyrrhizae, Radix Ophiopogonis and dandelion, is uniformly mixed after pulverizing and sieving, obtains mixing medicine
Powder；
Two, mixed powder obtained in step 1 being put into decoction vessel, the water that 6~10 times of quality of mixed powder are added decocts 1~
1.5h obtains decoction liquor；
Three, decoction liquor obtained in step 2 is concentrated after receiving juice and is dried to obtain powder, obtain treatment acute bronchitis
Chinese medicine composition.
6. preparation method according to claim 5, it is characterised in that: the aperture being sieved in the step 1 is 150~300
Mesh.
7. preparation method according to claim 5, it is characterised in that: the water in the step 2 is distilled water or deionization
Water.
8. preparation method according to claim 5, it is characterised in that: the number decocted in the step 2 is 2~3 times.
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Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189610A (en) * | 2014-09-22 | 2014-12-10 | 冯秀丽 | Traditional Chinese medicine composition for treating bronchitis |
| CN104666882A (en) * | 2015-03-30 | 2015-06-03 | 曲斌斌 | Traditional Chinese medicine granules for treating chronic bronchitis and preparation method of traditional Chinese medicine granules |
-
2016
- 2016-10-19 CN CN201610911398.3A patent/CN106421341B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN104189610A (en) * | 2014-09-22 | 2014-12-10 | 冯秀丽 | Traditional Chinese medicine composition for treating bronchitis |
| CN104666882A (en) * | 2015-03-30 | 2015-06-03 | 曲斌斌 | Traditional Chinese medicine granules for treating chronic bronchitis and preparation method of traditional Chinese medicine granules |
Non-Patent Citations (1)
| Title |
|---|
| 急性支气管炎的中医治疗;尹颖新;《职业与健康》;19951231;第64页 * |
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