CN106419803A - Intravascular opto-acoustic absorption, elasticity, viscosity multimode imaging integrated endoscopy and imaging method - Google Patents
Intravascular opto-acoustic absorption, elasticity, viscosity multimode imaging integrated endoscopy and imaging method Download PDFInfo
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- CN106419803A CN106419803A CN201610795903.2A CN201610795903A CN106419803A CN 106419803 A CN106419803 A CN 106419803A CN 201610795903 A CN201610795903 A CN 201610795903A CN 106419803 A CN106419803 A CN 106419803A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B1/00—Instruments for performing medical examinations of the interior of cavities or tubes of the body by visual or photographical inspection, e.g. endoscopes; Illuminating arrangements therefor
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- A—HUMAN NECESSITIES
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- A61B5/0093—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy
- A61B5/0095—Detecting, measuring or recording by applying one single type of energy and measuring its conversion into another type of energy by applying light and detecting acoustic waves, i.e. photoacoustic measurements
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/08—Detecting organic movements or changes, e.g. tumours, cysts, swellings
- A61B8/0891—Detecting organic movements or changes, e.g. tumours, cysts, swellings for diagnosis of blood vessels
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61B—DIAGNOSIS; SURGERY; IDENTIFICATION
- A61B8/00—Diagnosis using ultrasonic, sonic or infrasonic waves
- A61B8/44—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device
- A61B8/4444—Constructional features of the ultrasonic, sonic or infrasonic diagnostic device related to the probe
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Abstract
The invention belongs to the technical field of endoscopes and discloses an intravascular opto-acoustic absorption, elasticity, viscosity multimode imaging integrated endoscopy and an imaging method. The endoscope device comprises a photoacoubtic signal excitation assembly, a rotation assembly, a signal acquisition assembly, a signal processing and image reconstructing assembly; the photoacoubtic signal excitation assembly comprises a pulse laser, an optical fiber coupler, a multimode optical fiber, an optical fiber slip ring, a focus GRIN lens and a coating reflector; the rotation assembly comprises a stepper motor, an electric slip ring and a torque coil; the signal acquisition assembly comprises an ultrasonic transducer and a data collection card; the signal processing and image reconstructing assembly comprises an amplifier, a preamplifier, an oscilloscope, a lock-in amplifier and a computer; the diameter of the multimode endoscope is 1mm which can realize simultaneous acquisition imaging of three imaging modes or selected imaging of a single mode. The integrated endoscope integrates three imaging modes and advantages thereof; by means of the integrated endoscope, intravascular multi-parameter physical information and multi-scale structural imaging can be obtained.
Description
Technical field
The invention belongs to endoscope technical field of nondestructive testing, particularly to a kind of absorption of intravascular photoacoustic, elasticity, viscosity
Multi-modality imaging integration endoscope apparatus and imaging method.
Background technology
At present, existing Ink vessel transfusing sight glass, such as intravascular ultrasound imaging or photoacoustic imaging endoscope, are with ultrasonic or light
As exciting source excitation vascular tissue, obtain the ultrasonic signal amplitude size of vasoreflex, the amplitude according to receipt signal is entering
Row back projection imaging, only obtains the absorption information to light for the vascular tissue, can not comprehensive, truly accurately blood vessel is carried out
Pass judgment on.
Application No. 201110008213.5, patent name is《Photoacoustic elastic imaging method and its device》Document open
A kind of technology, this technology utilizes the continuous light source of intensity modulated to produce photoacoustic signal, by measuring this signal and modulated signal
Phase difference and point by point scanning, reconstruct the elasticity distribution image of sample.But in the above-mentioned methods, can not show that viscosity is joined
Number is it is impossible to realize viscosity imaging, and is 1 square millimeter using spot size after lens focus, and the image resolution ratio of formation is low.
The patent of Application No. 201210220399.5 discloses a kind of " focusing rotation sweep photoacoustic ultrasound blood vessel endoscope
Imaging device and its imaging method ", this technology carries out sound focusing using double array element ultrasonic transducers it is achieved that focusing Ink vessel transfusing
Photoacoustic ultrasound is imaged.But what this device obtained be endovascular reflectance ultrasound with light sound absorption it is impossible to provide elasticity become with viscosity
Picture, and the angles and positions difficulty of matching of double array element ultrasonic transducer is high, not high to the reduction accuracy of receipt signal and
Light is not focused, and resolution ratio is poor.
Content of the invention
Present invention is primarily targeted at overcoming shortcoming and the deficiency of prior art, provide a kind of intravascular photoacoustic to absorb,
Elasticity, viscosity multi-modality imaging endoscope apparatus and its imaging method, this endoscope can carry out the imaging of Three models, reflects blood vessel
Interior histological difference, and obtain elasticity and the sticky parameter of blood vessel.
In order to achieve the above object, the present invention employs the following technical solutions：
The invention provides a kind of intravascular photoacoustic absorption, elasticity, viscosity multi-modality imaging integration endoscope, including：Light
Acoustical signal excitation component, rotary components, signals collecting assembly, signal transacting and image reconstruction assembly；
Described photoacoustic signal excitation component includes pulse laser, fiber coupler, multimode fibre, optical fiber slip ring, focusing
Grin lenses and metallic-membrane plating reflector；Described rotary components include stepper motor, electric slip ring and moment of torsion coil；Described signals collecting group
Part includes ultrasonic transducer data capture card；Described signal transacting and image reconstruction assembly include amplifier, preamplifier,
Oscillograph, lock-in amplifier and computer；
Described fiber coupler, optical fiber, optical fiber slip ring, electric slip ring, moment of torsion coil, multimode fibre, focusing grin lenses, plating
Film speculum, ultrasonic transducer and integrated casing sequentially coaxially mechanical fasteners；Described pulse laser, oscillograph, lock are mutually put
Big device, ultrasonic transducer, data collecting card and computer are electrically connected successively；Described pulse laser is with lock-in amplifier even
Connect；Described lock-in amplifier one side is connected with computer, is on the other hand connected with lock-in amplifier, ultrasonic transducer；Described
Pulse laser is connected with oscillograph, and described oscillograph one side is connected with ultrasonic transducer, is on the other hand connected with computer.
As preferred technical scheme, described multimode fibre tail end, focus on grin lenses, metallic-membrane plating reflector and ultrasonic
Transducer unification is assemblied in integrated casing and is assembled into Ink vessel transfusing sight glass, and endoscope diameter is 1mm, and total length is 8mm.
As preferred technical scheme, described ultrasonic transducer is Ink vessel transfusing viscoplasticity ultrasonic probe, center probe frequency
For 3MHz, receive the frequency range 1.5MHz～4.5MHz of ultrasonic signal, ultrasonic transducer a size of long 4mm, wide 0.6mm, height
0.7mm；Described Ink vessel transfusing viscoplasticity ultrasonic probe is made up of composite wafer, matching layer and back lining materials, and using carrying on the back again
The preparation method of material individual layer matching layer is made, and can obtain high-resolution light acoustic intelligence, also can be processed by lock-in amplifier and obtain
Phase information in operating frequency range.
As preferred technical scheme, described focusing grin lenses are focussed collimated lens, burnt a length of 4mm, and and plated film
Speculum glue even, focuses on a diameter of 0.5mm of grin lenses.
As preferred technical scheme, described metallic-membrane plating reflector is used for increasing reflection power, its be right-angle prism, inclined-plane with
The angle of right-angle side is respectively 30 ° and 60 °, so, output light and exit facet angle are 30 °.
As preferred technical scheme, described multimode fibre output light line focus grin lenses and metallic-membrane plating reflector reflect
Laser spot afterwards is located at the surface of ultrasonic transducer.
As preferred technical scheme, described stepper motor includes rotating stepper motor and translation stepper motor, is two
Phase step motor, minimum step angle is 0.9 °；Described rotating stepper motor is used for rotation sweep, and described translation stepper motor is used for
Scan through the scanning of the advance after a circle.
As preferred technical scheme, described pulse laser repetition rate is 3MHz, using the maximum lock of lock-in amplifier
Phase frequency is 3MHz.
As preferred technical scheme, described lock-in amplifier uses 16 digit weighted-voltage D/A converters, and maximum frequency of phase locking is
3MHz, using FPGA+ARM platform architecture, based on digital modulation, output filter, can accurately and fast measure and be submerged in greatly
Useful signal component in noise, suppresses useless noise, improves detection signal-to-noise ratio, and obtains the phase information of photoacoustic signal, meter
Calculate viscoelastic ratio.
Present invention also offers a kind of intravascular photoacoustic absorption, elasticity, the imaging of viscosity multi-modality imaging integration endoscope
Method, comprises the steps：
(1) excite：Pulse laser exports pulse laser, and pulse laser is coupled into multimode fibre through fiber coupler,
It is then passed through focusing on grin lenses collimation focusing through optical fiber slip ring from the pulsed light of optical fiber output, enter speculum, by speculum
Reflex to blood vessel and inspire photoacoustic signal；
(2) gather：Excite the photoacoustic signal of generation in blood vessel tissue, detected by ultrasonic transducer, amplified device
It is divided into three tunnels after amplification：A part is transferred to high-speed data acquisition card collection storage in computer；Another part is amplified
Device is transferred in oscillograph after amplifying, and draws the rise time of displacement after process；Part III is transferred to warp in preamplifier
It is transferred to after amplification in lock-in amplifier, draws phase difference, finally all data all collect in a computer；
(3) scan：After completing the photoacoustic signal collection of a certain position, the control software on computer controls stepper motor
Rotated, stepper motor rotarily drives moment of torsion coil and integrated sight glass synchronous rotary, until having gathered one week, displacement steps
Stepper motor moves, and the next position is carried out with the collection of photoacoustic signal, so, until the annular completing whole blood vessel is swept
Retouch；
(4) image reconstruction and display：Record simultaneously processes photoacoustic signal data on image processing software, can carry out optoacoustic
Imaging, can draw the rise time of sample surfaces vibration displacement, can obtain elastic parameter, by following further according to oscillograph
Formula：
E=2.998 ρ (R/tmax)2
Wherein, E is elastic modelling quantity, and ρ is biological tissue density, and R is spot radius, tmaxFor sample surfaces vibration displacement
Rise time, the rise time measuring sample surfaces vibration displacement can draw elastic modelling quantity, can carry out elastogram；Again by locking
Phase amplifier draws the phase difference δ detecting signal and initial signal, can basis
Tan δ=η ω/E,
Obtain viscosity image；Wherein, δ is phase difference, and η is viscosity, and ω is the repetition rate of laser instrument, and E is elastic modelling quantity.
Formed by Three models, image is shown on the display of computer.
The present invention compared with prior art, has the advantage that and beneficial effect：
(1) present invention achieves light sound absorption, elasticity and viscosity are imaged three kinds of blood vessel endoscope imaging method integrations, simplify
Detection means, it is possible to achieve three kinds of imaging patterns carry out simultaneously.
(2) present invention can obtain the external morphology of vascular tissue, elasticity, three parameters of viscosity difference simultaneously, by right
Improve accuracy of detection, resolution ratio than these three parameters.
(3) present invention optimizes elasticity and viscosity imaging technique, elastogram and viscosity imaging have been attached to endoscope
In, enrich the information of endoscope acquisition.
Brief description
Fig. 1 is intravascular photoacoustic absorption of the present invention, elasticity, the schematic diagram of viscosity multimode endoscopic imaging device
Fig. 2 is intravascular photoacoustic absorption of the present invention, elasticity, the structural representation of viscosity integrated probe multi-modality imaging endoscope
Figure.Wherein, Fig. 3 is the graph of a relation of photoacoustic signal and sample surfaces vibration displacement.
Fig. 4 is to lock the signal graph mutually amplifying the photoacoustic signal receiving and former laser triggering.
Drawing reference numeral explanation：1st, pulse laser；2nd, fiber coupler；3rd, optical fiber slip ring；4th, motor；5th, electric slip ring；6、
Endoscope；7th, computer；8th, lock-in amplifier；9th, preamplifier；10th, amplifier；11st, oscillograph；12nd, optical fiber；13rd, focus on
Grin lenses；14th, it is metallic-membrane plating reflector；15th, it is ultrasonic transducer.
Specific embodiment
With reference to embodiment and accompanying drawing, the present invention is described in further detail, but embodiments of the present invention do not limit
In this.
Embodiment
Intravascular photoacoustic of the present invention absorbs, elastic, structural representation such as Fig. 1 institute of viscosity multimode endoscopic imaging device
Show：Wherein, 1 is pulse laser, and 2 is fiber coupler, and 3 is optical fiber slip ring, and 4 is motor, and 5 is electric slip ring, and 6 is Ink vessel transfusing light
Sound absorption, elasticity, viscosity integration endoscope, 7 is computer, and 8 is lock-in amplifier, and 9 is preamplifier, and 10 is to amplify
Device, 11 is oscillograph.
Fig. 2 is intravascular photoacoustic absorption of the present invention, elasticity, the structural representation of viscosity integration endoscope.Wherein, 12 are
Optical fiber, 13 is to focus on grin lenses, and 14 is metallic-membrane plating reflector, and 15 is ultrasonic transducer.
Described smooth sound absorption, elasticity, peep in viscosity multi-modality imaging, fiber coupler, optical fiber, optical fiber slip ring, electric slip ring,
Moment of torsion coil, multimode fibre, focusing grin lenses, metallic-membrane plating reflector, ultrasonic transducer sequentially coaxially mechanical fasteners；Pulse laser
Device, oscillograph and lock-in amplifier and ultrasonic transducer, data collecting card and computer are electrically connected successively.Pulse laser with
Lock-in amplifier connects, and lock-in amplifier is connected with computer, and lock-in amplifier is connected with ultrasonic transducer, pulse laser and
Oscillograph connects, and oscillograph is connected with ultrasonic transducer, and oscillograph is connected with computer.
Described pulse laser synchronism output lock-in amplifier and oscillograph.The photoacoustic signal that ultrasonic transducer receives
It is transferred to lock-in amplifier and oscillograph, respectively obtain phase difference and the rise time is transmitted further to computer disposal, obtain image.
Described pulse laser output pulsed light, is coupled into multimode fibre through fiber coupler, by light slip ring it
Afterwards, line focus grin lenses focus on, and are reflected by a reflector blood vessel, inspire photoacoustic signal by optoacoustic effect, the light inspiring
Acoustical signal is received by ultrasonic transducer, and photoacoustic signal is converted into electric signal, is transferred to lock-in amplifier and oscillograph.
In the present embodiment, described multimode fibre tail end, focusing grin lenses, metallic-membrane plating reflector and ultrasonic transducer
Unification is assemblied in integrated casing and is assembled into Ink vessel transfusing sight glass, and endoscope diameter is 1mm, and total length is 8mm.
Described ultrasonic transducer is Ink vessel transfusing viscoplasticity ultrasonic probe, and center probe frequency is 3MHz, receives ultrasonic signal
Frequency range 1.5MHz～4.5MHz, a size of long 4mm of ultrasonic transducer, wide 0.6mm, high 0.7mm；Described Ink vessel transfusing viscoelastic
Property ultrasonic probe be made up of composite wafer, matching layer and back lining materials, and using weight backing individual layer matching layer making side
Method is made, and can obtain high-resolution light acoustic intelligence, also can process, by lock-in amplifier, the phase place obtaining in operating frequency range
Information.
Described focusing grin lenses are focussed collimated lens, burnt a length of 4mm, and connect with metallic-membrane plating reflector glue, focus on GRIN
Lens diameter is 0.5mm.
Described metallic-membrane plating reflector is used for increasing reflection power, and it is right-angle prism, and inclined-plane is respectively with the angle of right-angle side
30 ° and 60 °, so, output light and exit facet angle are 30 °.
Laser spot after described multimode fibre output light line focus grin lenses and metallic-membrane plating reflector reflection is located at super
The surface of sonic transducer.
Described stepper motor includes rotating stepper motor and translation stepper motor, is two-phase stepping motor, minimum step
Angle is 0.9 °；Described rotating stepper motor is used for rotation sweep, and described translation stepper motor is used for the advance after scanning through a circle
Scanning.
Described pulse laser repetition rate is 3MHz, the use of lock-in amplifier maximum frequency of phase locking is 3MHz.
Idiographic flow when Fig. 1 shown device is imaged is as follows：
(1) excite：Open pulse laser, debugging pulse laser exports the pulse laser of suitable energy, pulse laser
It is coupled into multimode fibre through fiber coupler, be then passed through focusing on grin lenses through optical fiber slip ring from the pulsed light of optical fiber output
Collimation focusing, enters speculum, reflexes to blood vessel by speculum and inspire photoacoustic signal.
(2) gather：Excite the photoacoustic signal of generation in blood vessel tissue, detected by ultrasonic transducer, amplified device
It is divided into three tunnels after amplification：A part is transferred to high-speed data acquisition card (pulse laser synchronously triggering) collection storage and arrives and calculate
In machine；The amplified device of another part is transferred in oscillograph after amplifying, and draws the rise time of displacement after process；Another part passes
Defeated amplified in preamplifier be transferred in lock-in amplifier, draw phase difference.Finally all data are all summarised in
In computer.
(3) scan：After completing the photoacoustic signal collection of a certain position, the control software on computer controls stepper motor
Rotated, stepper motor rotarily drives moment of torsion coil and integrated sight glass synchronous rotary, until having gathered one week, displacement steps
Stepper motor moves, and the next position is carried out with the collection of photoacoustic signal, so, until the annular completing whole blood vessel is swept
Retouch.
(4) image reconstruction and display：Record simultaneously processes photoacoustic signal data on image processing software, is entered using algorithm
Row projection, obtains the photoacoustic image of blood vessel, elastic image and viscosity image；Image formed by Three models is shown in calculating
On the display of machine.
Above-described embodiment is the present invention preferably embodiment, but embodiments of the present invention are not subject to above-described embodiment
Limit, other any Spirit Essences without departing from the present invention and the change made under principle, modification, replacement, combine, simplify,
All should be equivalent substitute mode, be included within protection scope of the present invention.
Claims (10)
1. a kind of intravascular photoacoustic absorption, elasticity, viscosity multi-modality imaging integration endoscope are it is characterised in that include：Optoacoustic is believed
Number excitation component, rotary components, signals collecting assembly, signal transacting and image reconstruction assembly；
Described photoacoustic signal excitation component includes pulse laser, fiber coupler, multimode fibre, optical fiber slip ring, focuses on GRIN
Lens and metallic-membrane plating reflector；Described rotary components include stepper motor, electric slip ring and moment of torsion coil；Described signals collecting assembly bag
Include ultrasonic transducer data capture card；Described signal transacting and image reconstruction assembly include amplifier, preamplifier, oscillography
Device, lock-in amplifier and computer；
Described fiber coupler, optical fiber, optical fiber slip ring, electric slip ring, moment of torsion coil, multimode fibre, focusing grin lenses, plated film are anti-
Penetrate mirror, ultrasonic transducer and integrated casing sequentially coaxially mechanical fasteners；Described pulse laser, oscillograph, lock-in amplifier,
Ultrasonic transducer, data collecting card and computer are electrically connected successively；Described pulse laser is connected with lock-in amplifier；Described
Lock-in amplifier one side is connected with computer, is on the other hand connected with lock-in amplifier, ultrasonic transducer；Described pulse laser
Device is connected with oscillograph, and described oscillograph one side is connected with ultrasonic transducer, is on the other hand connected with computer.
2. intravascular photoacoustic absorption according to claim 1, elasticity, viscosity multi-modality imaging integration endoscope, its feature
It is, described multimode fibre tail end, focusing grin lenses, metallic-membrane plating reflector and ultrasonic transducer unification are assemblied in integration
Inside the shell is assembled into Ink vessel transfusing sight glass, and endoscope diameter is 1mm, and total length is 8mm.
3. intravascular photoacoustic absorption according to claim 1, elasticity, viscosity multi-modality imaging integration endoscope, its feature
It is, described ultrasonic transducer is Ink vessel transfusing viscoplasticity ultrasonic probe, center probe frequency is 3MHz, receives the frequency of ultrasonic signal
Rate scope 1.5MHz～4.5MHz, a size of long 4mm of ultrasonic transducer, wide 0.6mm, high 0.7mm；Described Ink vessel transfusing viscoplasticity surpasses
Sonic probe is made up of composite wafer, matching layer and back lining materials, and the preparation method system using weight backing individual layer matching layer
Become, high-resolution light acoustic intelligence can be obtained, also the phase information obtaining in operating frequency range can be processed by lock-in amplifier.
4. intravascular photoacoustic absorption according to claim 1, elasticity, viscosity multi-modality imaging integration endoscope, its feature
It is, described focusing grin lenses are focussed collimated lens, burnt a length of 4mm, and connect with metallic-membrane plating reflector glue, focus on grin lenses
A diameter of 0.5mm.
5. intravascular photoacoustic absorption according to claim 1, elasticity, viscosity multi-modality imaging integration endoscope, its feature
It is, described metallic-membrane plating reflector is used for increasing reflection power, it is right-angle prism, inclined-plane is respectively 30 ° with the angle of right-angle side
With 60 °, so, output light and exit facet angle are 30 °.
6. intravascular photoacoustic absorption according to claim 1, elasticity, viscosity multi-modality imaging integration endoscope, its feature
It is, the laser spot after described multimode fibre output light line focus grin lenses and metallic-membrane plating reflector reflection is located at ultrasonic changing
The surface of energy device.
7. intravascular photoacoustic absorption according to claim 1, elasticity, viscosity multi-modality imaging integration endoscope, its feature
It is, described stepper motor includes rotating stepper motor and translation stepper motor, be two-phase stepping motor, minimum step angle is
0.9°；Described rotating stepper motor is used for rotation sweep, and the advance after described translation stepper motor is used for scanning through a circle scans.
8. intravascular photoacoustic absorption according to claim 1, elasticity, viscosity multi-modality imaging integration endoscope, its feature
It is, described pulse laser repetition rate is 3MHz, the use of lock-in amplifier maximum frequency of phase locking is 3MHz.
9. intravascular photoacoustic absorption according to claim 1, elasticity, viscosity multi-modality imaging integration endoscope, its feature
It is, described lock-in amplifier uses 16 digit weighted-voltage D/A converters, maximum frequency of phase locking is 3MHz, using FPGA+ARM paralell
Structure, based on digital modulation, output filter, can accurately and fast measure the useful signal component being submerged in big noise, suppression
Make useless noise, improve detection signal-to-noise ratio, and obtain the phase information of photoacoustic signal, calculate viscoelastic ratio.
10. a kind of intravascular photoacoustic absorb, the imaging method of elasticity, viscosity multi-modality imaging integration endoscope it is characterised in that
Comprise the steps：
(1) excite：Pulse laser exports pulse laser, and pulse laser is coupled into multimode fibre through fiber coupler, from light
The pulsed light of fine output is then passed through focusing on grin lenses collimation focusing through optical fiber slip ring, enters speculum, is reflected by speculum
Inspire photoacoustic signal to blood vessel；
(2) gather：Excite the photoacoustic signal of generation in blood vessel tissue, detected by ultrasonic transducer, amplified device amplifies
After be divided into three tunnels：A part is transferred to high-speed data acquisition card collection storage in computer；The amplified device of another part is put
It is transferred in oscillograph after big, after process, draw the rise time of displacement；Part III is transferred to amplified in preamplifier
After be transferred in lock-in amplifier, draw phase difference, finally all data all collect in a computer；
(3) scan：After completing the photoacoustic signal collection of a certain position, the control software on computer controls stepper motor to carry out
Rotation, stepper motor rotarily drives moment of torsion coil and integrated sight glass synchronous rotary, until having gathered one week, displacement stepping electricity
Machine moves, and the next position is carried out with the collection of photoacoustic signal, so, until completing the circular scanning of whole blood vessel；
(4) image reconstruction and display：Record simultaneously processes photoacoustic signal data on image processing software, can carry out optoacoustic one-tenth
Picture, can draw the rise time of sample surfaces vibration displacement further according to oscillograph, can obtain elastic parameter, by following public affairs
Formula：
E=2.998 ρ (R/tmax)2
Wherein, E is elastic modelling quantity, and ρ is biological tissue density, and R is spot radius, tmaxRising for sample surfaces vibration displacement
Time, the rise time measuring sample surfaces vibration displacement can draw elastic modelling quantity, can carry out elastogram；Mutually put by locking again
Big device draws the phase difference δ detecting signal and initial signal, can basis
Tan δ=η ω/E,
Obtain viscosity image；Wherein, δ is phase difference, and η is viscosity, and ω is the repetition rate of laser instrument, and E is elastic modelling quantity；Three kinds
Formed by pattern, image is shown on the display of computer.
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