CN106399850A - Antibacterial stainless steel applied to general surgical operating instrument - Google Patents
Antibacterial stainless steel applied to general surgical operating instrument Download PDFInfo
- Publication number
- CN106399850A CN106399850A CN201610754048.0A CN201610754048A CN106399850A CN 106399850 A CN106399850 A CN 106399850A CN 201610754048 A CN201610754048 A CN 201610754048A CN 106399850 A CN106399850 A CN 106399850A
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- Prior art keywords
- stainless steel
- antibacterial
- bacteria stainless
- operating instrument
- surgical operating
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- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C38/00—Ferrous alloys, e.g. steel alloys
- C22C38/18—Ferrous alloys, e.g. steel alloys containing chromium
- C22C38/20—Ferrous alloys, e.g. steel alloys containing chromium with copper
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/02—Inorganic materials
- A61L31/022—Metals or alloys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L31/00—Materials for other surgical articles, e.g. stents, stent-grafts, shunts, surgical drapes, guide wires, materials for adhesion prevention, occluding devices, surgical gloves, tissue fixation devices
- A61L31/14—Materials characterised by their function or physical properties, e.g. injectable or lubricating compositions, shape-memory materials, surface modified materials
- A61L31/16—Biologically active materials, e.g. therapeutic substances
-
- C—CHEMISTRY; METALLURGY
- C21—METALLURGY OF IRON
- C21D—MODIFYING THE PHYSICAL STRUCTURE OF FERROUS METALS; GENERAL DEVICES FOR HEAT TREATMENT OF FERROUS OR NON-FERROUS METALS OR ALLOYS; MAKING METAL MALLEABLE, e.g. BY DECARBURISATION OR TEMPERING
- C21D6/00—Heat treatment of ferrous alloys
- C21D6/002—Heat treatment of ferrous alloys containing Cr
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C38/00—Ferrous alloys, e.g. steel alloys
- C22C38/005—Ferrous alloys, e.g. steel alloys containing rare earths, i.e. Sc, Y, Lanthanides
-
- C—CHEMISTRY; METALLURGY
- C22—METALLURGY; FERROUS OR NON-FERROUS ALLOYS; TREATMENT OF ALLOYS OR NON-FERROUS METALS
- C22C—ALLOYS
- C22C38/00—Ferrous alloys, e.g. steel alloys
- C22C38/007—Ferrous alloys, e.g. steel alloys containing silver
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/10—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices containing or releasing inorganic materials
- A61L2300/102—Metals or metal compounds, e.g. salts such as bicarbonates, carbonates, oxides, zeolites, silicates
- A61L2300/104—Silver, e.g. silver sulfadiazine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L2300/00—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices
- A61L2300/40—Biologically active materials used in bandages, wound dressings, absorbent pads or medical devices characterised by a specific therapeutic activity or mode of action
- A61L2300/404—Biocides, antimicrobial agents, antiseptic agents
Abstract
The invention discloses antibacterial stainless steel applied to a general surgical operating instrument. The general surgical operating instrument is made of the antibacterial stainless steel. The alloy component of the antibacterial stainless steel comprises one or more of the Cu element, the Ag element and the rare earth element, and the content of the surface antibacterial element is larger than or equal to 10% by the atom percentage; moreover, the surface roughness Ra of the antibacterial stainless steel surgical operating instrument material is larger than or equal to 0.4; and accordingly, the timely lasting bacteriostasis and antibacterial functions of the antibacterial stainless steel general surgical operating instrument in the surgery process can be ensured. The antibacterial stainless steel related to the invention has a unique broad-spectrum antibacterial property, the using method and the using condition of the antibacterial stainless steel as the specific product mode of the general surgical operating instrument are determined, and infection risks caused by long-time surgery and bacterial reproduction in the external environment can be effectively reduced.
Description
Technical field
The present invention relates to metal material material and anti-biotic material technical field are and in particular to one kind is applied to general surgery handss
Anti-bacteria stainless steel in art apparatus.
Background technology
Anti-bacteria stainless steel refers to that a class relies on the slight erosion that rustless steel itself occurs to lead to as Cu, Ag and LREE
Antibacterial, sterilization purpose metal material and anti-biotic material are reached etc. the micro release of antiseptic elements.The end of the nineties in last century, Japan
Silver-containing antibacterial rustless steel R304-AB, R430-AB and R430LN- are developed in Kawasaki Steel Corp's announcement that takes the lead in the world
AB, it reaches more than 99% to colibacillary sterilizing rate, shows excellent anti-microbial property.Subsequently day brand-new steel company of Japan
Develop have good three kinds of serial copper-bearing antibacterial rustless steel NSSAM1, NSSAM manufacturing processing characteristics and anti-microbial property and
NSS3, it has very strong killing to make to common bacterias such as staphylococcus aureuses, escherichia coli, bacillus pyocyaneus, Salmonellas
With.
The primary limitation that prior art exists in common surgical procedures Application of device is:
(1) at present, the method that the detection method of stainless-steel antibacterial energy generally individually adopts standard, as Japan
JISZ2801, international standard ISO22196 and China GB21551.2.Antibiotic method described in these standards, its common trait
It is, test the antibacterial or antibacterial situation of single antibacterial, and initial bacterial concentration is higher.Its limitation is it is impossible to truly anti-
Reflect the antibacterial of the environment being actually needed antibacterial or bactericidal effect.Actual environment is often complex, and various bacteria is posted mutually
Life coexists, and bacterial concentration compares typically relatively low with experimental situation, and is typically required to antibacterial effect demand faster.
(2) antibacterial design of existing stainless steel material is generally based on control antiseptic elements chemical compositions by percentage (such as
Cu, Ag and rare earth element) and antibacterial heat-treatment set out.Therefore appropriate antiseptic elements and antibacterial heat-treatment be two can not or
Scarce essential condition.The method be based on anti-bacteria stainless steel be Ion release type principle design of material.And Ion release type by
In needing antibacterial ion to be to realize by self-diffusion from material matrix surface, it is very slow, typically that diffusion rate is envisioned that
The action time reaching antibacterial requirement at least will exceed 12 hours, and general operating time is shorter, needs anti-biotic material to send out in time
Wave effect.In addition, in the art that faced of common surgical procedures apparatus environment be often dry and humidity less it is desirable to material
Antibacterial mechanisms should be contact sterilization type.Contact sterilization type requires to the surface energy of material, and commaterial
Surface energy is again directly related with roughness grade number.Roughness Ra is less, and surface energy is less, is more unfavorable at the sterilization of anti-biotic material
Reason.
Content of the invention
Present invention aims to the defect of prior art and deficiency, one kind is provided to be applied to common surgical procedures device
Anti-bacteria stainless steel in tool, this anti-bacteria stainless steel has the broad spectrum antibacterial performance of uniqueness, specify that it as common surgical procedures
Usage and use condition that this specific productss form of apparatus should have, effectively reduce due to operating time longer and because of external rings
The infection risk that border bacterial reproduction brings, can be widely applied to environment in art is the harsh wild environment such as earthquake relief work.
For achieving the above object, the present invention employs the following technical solutions：Anti-bacteria stainless steel is made common surgical procedures device
Tool, contains one or more of Cu element, Ag element and rare earth element in the alloying component of described anti-bacteria stainless steel, surface resists
Bacterium element, based on atom percentage content, answers >=10%；And anti-bacteria stainless steel surgical operating instrument material surface roughness Ra >=
0.4.
Preferably, described operating theater instruments include a class or two class anti-bacteria stainless steel operating theater instruments.
Preferably, described antibacterial surface Elements Atom percentage ratio can be obtained by the long-time aging of existing anti-bacteria stainless steel
Obtain it is also possible to be obtained by the method for material surface ion sputtering.
Preferably, described anti-bacteria stainless steel long-time aging time >=15 hour.
After above-mentioned technology, the invention has the advantages that：
1st, the present invention, using anti-bacteria stainless steel as common surgical procedures apparatus, has opened up the purposes of anti-bacteria stainless steel, for
The development of anti-bacteria stainless steel material has preferable impetus.
2nd, in the present invention anti-bacteria stainless steel as common surgical procedures apparatus, for the particularity of its surgical environments, with reality
Based on the feature of border environment, propose anti-bacteria stainless steel material surface antiseptic elements atomic percent and surface roughness will
Ask, there is more accurately directivity.
3rd, in the present invention, anti-bacteria stainless steel, in the application of common surgical procedures apparatus, is that the application in varying environment is required
The design of material of anti-bacteria stainless steel, there is provided be worth the methodological study thinking used for reference.
Brief description
Fig. 1 is design of material and antibacterial testing result schematic diagram in the embodiment of the present invention.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation description is it is clear that described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.It is based on
Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under the premise of not making creative work
Embodiment, broadly falls into the scope of protection of the invention.
Embodiment：Anti-bacteria stainless steel material is chosen as 2Cr13Cu rustless steel.
This specific embodiment employs the following technical solutions：2Cr13Cu stainless steel chemical component is count by weight percentage
For：C：0.25%, Cr：13.5%, Cu：3.0%, balance of Fe；Print a size of 50 × 50 × 2mm.
Technology for Heating Processing is：In 980 DEG C of ± 10 DEG C of solution treatment 1 hour, it is air cooled to room temperature, is then being warming up to 400 DEG C
It is incubated 14,15 and 20 hours respectively, be air cooled to room temperature.Using X-ray photoelectron spectroscopic analysis technical testing sample surfaces antibacterial
The atomic percent of element Cu.
Surface roughness：Separately design Ra be 0.2,0.4 and 0.8 apparent condition anti-bacteria stainless steel print.
Antibacterial environment used：Staphylococcus aureuses and escherichia coli mixed vaccine, concentration is respectively 2 × 104CFU/mL.Anti-
Bacterium performance uses for reference " JIS Z 2801-2000《Antibacterial fabricated product-antibiotic property test method and antibacterial effect》、GB/T 2591-
2003《Antibiotic plastic anti-microbial property experimental technique and antibacterial effect》" etc. correlation standard.When wherein antibacterial is acted on print
Between be fixed as 2 hours.It is judged as with anti-microbial property when sterilizing rate is more than 90%.
Referring to Fig. 1, embodiment result shows, ought meet aging time using anti-bacteria stainless steel proposed by the present invention big simultaneously
Under conditions of 15 hours and surface roughness are more than 0.4, it is ensured that sterilizing rate all can exceed that in the action time of two hours
90%.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, permissible
Understand and can carry out multiple changes, modification, replacement to these embodiments without departing from the principles and spirit of the present invention
And modification, the scope of the present invention be defined by the appended.
Claims (5)
1. a kind of anti-bacteria stainless steel being applied in common surgical procedures apparatus it is characterised in that：Anti-bacteria stainless steel is made general
Logical surgical operating instrument, contains one of Cu element, Ag element and rare earth element in the alloying component of described anti-bacteria stainless steel
Or multiple, antibacterial surface element, based on atom percentage content, answers >=10%；And anti-bacteria stainless steel surgical operating instrument material list
Surface roughness Ra >=0.4.
2. a kind of anti-bacteria stainless steel being applied in common surgical procedures apparatus according to claim 1 it is characterised in that
Described operating theater instruments include a class or two class anti-bacteria stainless steel operating theater instruments.
3. a kind of anti-bacteria stainless steel being applied in common surgical procedures apparatus according to claim 1 it is characterised in that：
Described antibacterial surface Elements Atom percentage ratio can be obtained by the long-time aging of existing anti-bacteria stainless steel.
4. a kind of anti-bacteria stainless steel being applied in common surgical procedures apparatus according to claim 3 it is characterised in that：
Described antibacterial surface Elements Atom percentage ratio be can be replaced and obtained by the method for material surface ion sputtering.
5. a kind of anti-bacteria stainless steel being applied in common surgical procedures apparatus according to claim 3 it is characterised in that：
Described anti-bacteria stainless steel long-time aging time >=15 hour.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610754048.0A CN106399850A (en) | 2016-08-29 | 2016-08-29 | Antibacterial stainless steel applied to general surgical operating instrument |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610754048.0A CN106399850A (en) | 2016-08-29 | 2016-08-29 | Antibacterial stainless steel applied to general surgical operating instrument |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106399850A true CN106399850A (en) | 2017-02-15 |
Family
ID=58002434
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| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610754048.0A Pending CN106399850A (en) | 2016-08-29 | 2016-08-29 | Antibacterial stainless steel applied to general surgical operating instrument |
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| Country | Link |
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Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2288864A1 (en) * | 1998-03-16 | 1999-09-23 | Takeshi Yokota | Stainless steel having excellent antibacterial property and method for producing the same |
| TW554052B (en) * | 2002-10-25 | 2003-09-21 | Ind Tech Res Inst | An antibacteria stainless steel |
| CN1498981A (en) * | 2002-11-07 | 2004-05-26 | 中国科学院金属研究所 | Antibacterial stainless steel of ferrite in nano precipitated phase |
| CN1554795A (en) * | 2003-12-27 | 2004-12-15 | 张体勇 | High antibiotic property stainless steel |
| CN1924058A (en) * | 2005-08-30 | 2007-03-07 | 中国科学院金属研究所 | Rich rare earth stainless steel with excellent anti-bacterium capability |
| CN101205592A (en) * | 2006-12-19 | 2008-06-25 | 中国科学院金属研究所 | Martensitic antibiotic stainless steel and thermal treatment method thereof |
| CN101880860A (en) * | 2010-05-29 | 2010-11-10 | 太原理工大学 | Preparation method of stainless steel surface copper-silver diffusion coating layer |
| CN102787277A (en) * | 2011-05-18 | 2012-11-21 | 中国科学院金属研究所 | Medical nickel-free high-nitrogen austenite antimicrobial stainless steel, its preparation and its application |
| CN105088092A (en) * | 2014-05-23 | 2015-11-25 | 中国科学院金属研究所 | Novel medical antibacterial stainless steel |
-
2016
- 2016-08-29 CN CN201610754048.0A patent/CN106399850A/en active Pending
Patent Citations (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA2288864A1 (en) * | 1998-03-16 | 1999-09-23 | Takeshi Yokota | Stainless steel having excellent antibacterial property and method for producing the same |
| TW554052B (en) * | 2002-10-25 | 2003-09-21 | Ind Tech Res Inst | An antibacteria stainless steel |
| CN1498981A (en) * | 2002-11-07 | 2004-05-26 | 中国科学院金属研究所 | Antibacterial stainless steel of ferrite in nano precipitated phase |
| CN1554795A (en) * | 2003-12-27 | 2004-12-15 | 张体勇 | High antibiotic property stainless steel |
| CN1924058A (en) * | 2005-08-30 | 2007-03-07 | 中国科学院金属研究所 | Rich rare earth stainless steel with excellent anti-bacterium capability |
| CN101205592A (en) * | 2006-12-19 | 2008-06-25 | 中国科学院金属研究所 | Martensitic antibiotic stainless steel and thermal treatment method thereof |
| CN101880860A (en) * | 2010-05-29 | 2010-11-10 | 太原理工大学 | Preparation method of stainless steel surface copper-silver diffusion coating layer |
| CN102787277A (en) * | 2011-05-18 | 2012-11-21 | 中国科学院金属研究所 | Medical nickel-free high-nitrogen austenite antimicrobial stainless steel, its preparation and its application |
| CN105088092A (en) * | 2014-05-23 | 2015-11-25 | 中国科学院金属研究所 | Novel medical antibacterial stainless steel |
Non-Patent Citations (1)
| Title |
|---|
| 丁浩等: "《纳米抗菌技术》", 31 October 2007, 北京：化学工业出版社 * |
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Application publication date: 20170215 |
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