CN106398936A - Female healthcare wine for alleviating sleep disorders - Google Patents

Female healthcare wine for alleviating sleep disorders Download PDF

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Publication number
CN106398936A
CN106398936A CN201611182683.2A CN201611182683A CN106398936A CN 106398936 A CN106398936 A CN 106398936A CN 201611182683 A CN201611182683 A CN 201611182683A CN 106398936 A CN106398936 A CN 106398936A
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wine
sleep
health care
health
female
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杨凯
其他发明人请求不公开姓名
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Guangzhou Poly Health Industry Research Institute Co Ltd
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Guangzhou Poly Health Industry Research Institute Co Ltd
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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12GWINE; PREPARATION THEREOF; ALCOHOLIC BEVERAGES; PREPARATION OF ALCOHOLIC BEVERAGES NOT PROVIDED FOR IN SUBCLASSES C12C OR C12H
    • C12G1/00Preparation of wine or sparkling wine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/35Caprifoliaceae (Honeysuckle family)
    • A61K36/355Lonicera (honeysuckle)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/62Nymphaeaceae (Water-lily family)

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Medicinal Chemistry (AREA)
  • Organic Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • General Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)

Abstract

The invention provides a female healthcare wine for alleviating sleep disorders. The female healthcare wine comprises the following raw materials in parts by weight: 5-30 parts of honeysuckle organic acid, 3-20 parts of pachymaran, 5-20 parts of lotus seed polyphenol and the balance of grape wine, wherein the total parts are 1000. Due to cooperative application of the three medicines, namely, the honeysuckle organic acid, the pachymaran and the lotus seed polyphenol, the female healthcare wine has the functions of tranquilizing and allaying excitement and calming the nerve, nourishing the heart and tonifying the kidney, protecting the liver and nourishing the spleen, and the like, and meanwhile, on the basis of the grape wine, and with assistance of the qi and blood circulation property of wine, an effect of alleviating sleep disorders can be achieved.

Description

A kind of Female health wine improving the health care of sleep obstacle
Technical field
The invention belongs to field of health care products is and in particular to a kind of Female health wine improving the health care of sleep obstacle.
Background technology
Insomnia refers to fall asleep or cannot keep sleep state, leads to not have enough sleep, and hinders also known as falling asleep and maintaining to sleep Hinder.Sleep disorder causes quite a few crowd and is in " subhealth state " state.Sleep disorder often causes body immunity low Under, spirit irritated, be also easy to cause hypertension, neurasthenia, cardiovascular and cerebrovascular vessel accident and psychological disease etc. simultaneously, or even cause Sudden death.
With social development, insomnia has become as the Chinese medicine factor of puzzlement people's life.Improve the health care of sleep the research of obstacle Focus mostly in Western medicine, such as stable wait and melatonin etc. in terms of although having certain effect, but long-term taking can produce necessarily Dependency and side effect.
The patent No. 201410164958.4 discloses a kind of health preserving rice wine improving the health care of sleep obstacle, by following raw material Make:Rice wine 300-320, Fructus Musae 60-70, tamarind 30-40, milk 60-70, fructus zizaniae caduciflorae 20-30, Semen Juglandis 20-30, yellow wine 50- 60th, Mel 80-90, Flos Chrysanthemi 6-8, Rhizoma Polygonati 6-7, Semen Platycladi 5-6, the refreshing 5-6 of volt, Radix Rehmanniae 5-6, Semen Cassiae 6-7;The patent No. 201510103967.7 disclose a kind of beverage improving the health care of sleep obstacle, and the weight proportion of each raw material components of this beverage is:Lampwick Careless 10-15 part, fresh Folium Bambusae 10-15 part, fallen flowers leave 25-40 part, Fructus Schisandrae Chinensis 15-20 part, Fructus Tritici Levis 10-15 part, Cortex Albiziae 10- 15 parts, the refreshing 15-20 part of volt, Fructus Jujubae 15-20 part, Semen Ziziphi Spinosae 15-20 part, Radix Glycyrrhizae 8-20 part, crystal sugar 10-20 part and Mel 20-30 Part.
How the health product of the existing Chinese medicine composition for improving the health care of sleep obstacle, be made up of a variety of Chinese crude drugs, composition Complexity, is produced using traditional extraction method for concentration and process conditions, causes the effective ingredient of medical material or active component Extract not exclusively, have impact on effect of final products.
Content of the invention
It is an object of the invention to provide a kind of Female health wine improving the health care of sleep obstacle, this health promoting wine is according to Traditional Chinese health Theory, in conjunction with women physique characteristic, formula each taste medicine phases are mutually worked in coordination with, and reach the effect improving the health care of sleep obstacle.
A kind of Female health wine improving the health care of sleep obstacle, including following raw material:
Preferably, the described Female health wine improving the health care of sleep obstacle, including following raw material:
It is furthermore preferred that the described Female health wine improving the health care of sleep obstacle, including following raw material:
Most preferably, the described Female health wine improving the health care of sleep obstacle, including following raw material:
Preferably, the weight part ratio of described honeysuckle organic acid, pachyman and Semen Nelumbinis polyphenol is:10-28:5-18:8- 20.
It is furthermore preferred that the weight part ratio of described honeysuckle organic acid, pachyman and Semen Nelumbinis polyphenol is 15-25:8-15: 10-18.
Preferably, described wine is white wine, and Alcohol degree is 12-14%vol.
The Female health wine improving the health care of sleep obstacle of the present invention, its preparation method comprises the following steps:
1) allocate:Honeysuckle organic acid, pachyman, Semen Nelumbinis polyphenol and wine are placed in blend tank, and stirring and dissolving is equal After even, obtain mixed liquor;
2) stand:Mixed liquor stands 2~3 days;
3) filter:Using nuclepore membrane filter, pore size filter is 0.2~0.8 μm;
4) fill:Fill is in capacity in the burgundy bottle of 750mL.
Preferably, microporous filter membrane aperture is 0.45~0.65 μm.Microporous filter membrane aperture is excessive, and solid particle polluter has Part remains, the clarity of impact wine.Using the microporous filter membrane of 0.45~0.65 μm of size, solid particle, gained can be removed Health promoting wine entirety local flavor is full, liquid is limpid.
Honeysuckle organic acid be from the dry flower of caprifoliaceae plant Radix Ophiopogoniss extract and come, have heat-clearing and toxic substances removing, dredge Dissipate wind-heat acts on.Its main component is chlorogenic acid, has protective effect to liver and splenic trauma, and it also has antibacterial action in addition, Can be used as the preservative of health promoting wine of the present invention.
Pachyman is to extract from funguses Poria sporophore, is mainly made up of glucosan.It can improve cell Immunity, increases appetite, improves the health care of sleep obstacle and muscle power, alleviates anxiety.
Semen Nelumbinis polyphenol is to extract fruit after the seed of Nymphaeceae platymiscium shells and come, and it has calm peace God, invigorating the spleen and replenishing QI, nourishing the heart and kidney effect.It has stronger Scavenging ability, can purify blood, improve microcirculation.
The honeysuckle organic acid of the present invention, pachyman and three kinds of medicines of Semen Nelumbinis polyphenol are coordinated to use, have tranquillizing and allaying excitement, Nourishing the heart and kidney, hepatoprotective spleen invigorating etc. act on.Meanwhile, the present invention is with wine as base liquor, rich in several amino acids and micro unit Element, in addition three kinds of medicines of the present invention work in coordination with and use, play altogether and improve the health care of sleep obstacle effect.
Compared with prior art, the invention has the beneficial effects as follows:(1) middle the effective elements of the medicine is added directly into wine In, improve soak time length in Traditional health care wine preparation technology, effective ingredient dissolution rate is low and dissolution component is miscellaneous defect; (2) with wine as base liquor, it belongs to alkaline drink wine, and Alcohol degree is low, and suitable women can adjust body constitution acidity degree;(3) Honeysuckle organic acid, pachyman and three kinds of medicines of Semen Nelumbinis polyphenol are coordinated to use, and have tranquillizing and allaying excitement, nourishing the heart and kidney, hepatoprotective are good for Spleen etc. acts on, and meanwhile, with wine as base liquor, by the power of the venting QI-blood of wine, plays the effect of improve the health care of sleep obstacle altogether; (4) raw material is all belonging to the material that the medicine-food two-purpose that food and medicine Surveillance Authority specifies can be used for health food, nontoxic secondary makees With.
Specific embodiment
With reference to specific embodiment, the present invention is further described, but embodiment of the present invention is not limited only to this.
Embodiment 1
A kind of Female health wine improving the health care of sleep obstacle, including following raw material:5 parts of honeysuckle organic acid, Poria 17 parts of polysaccharide, 20 parts of Semen Nelumbinis polyphenol, the white wine of balance of 12%vol, totally 1000 parts.
Preparation method:The white wine of honeysuckle organic acid, pachyman, Semen Nelumbinis polyphenol and 12%vol is placed in allotment In tank, after stirring and dissolving is uniform, obtain mixed liquor;Mixed liquor stands 2 days;Using nuclepore membrane filter, pore size filter is 0.8 μ m;Fill is in capacity in the burgundy bottle of 750mL.
Embodiment 2
A kind of Female health wine improving the health care of sleep obstacle, including following raw material:18 parts of honeysuckle organic acid, Poria 20 parts of polysaccharide, 5 parts of Semen Nelumbinis polyphenol, the red wine of balance of 12%vol, totally 1000 parts.
Preparation method:The red wine of honeysuckle organic acid, pachyman, Semen Nelumbinis polyphenol and 12%vol is placed in allotment In tank, after stirring and dissolving is uniform, obtain mixed liquor;Mixed liquor stands 2 days;Using nuclepore membrane filter, pore size filter is 0.22 μ m;Fill is in capacity in the burgundy bottle of 750mL.
Embodiment 3
A kind of Female health wine improving the health care of sleep obstacle, including following raw material:30 parts of honeysuckle organic acid, Poria 3 parts of polysaccharide, 10 parts of Semen Nelumbinis polyphenol, the white wine of balance of 14%vol, totally 1000 parts.
Preparation method:The white wine of honeysuckle organic acid, pachyman, Semen Nelumbinis polyphenol and 14%vol is placed in allotment In tank, after stirring and dissolving is uniform, obtain mixed liquor;Mixed liquor stands 3 days;Using nuclepore membrane filter, pore size filter is 0.65 μ m;Fill is in capacity in the burgundy bottle of 750mL.
Embodiment 4
A kind of Female health wine improving the health care of sleep obstacle, including following raw material:10 parts of honeysuckle organic acid, Poria 8 parts of polysaccharide, 9 parts of Semen Nelumbinis polyphenol, the red wine of balance of 14%vol, totally 1000 parts.
Preparation method:The red wine of honeysuckle organic acid, pachyman, Semen Nelumbinis polyphenol and 14%vol is placed in allotment In tank, after stirring and dissolving is uniform, obtain mixed liquor;Mixed liquor stands 2 days;Using nuclepore membrane filter, pore size filter is 0.45 μ m;Fill is in capacity in the burgundy bottle of 750mL.
Embodiment 5
A kind of Female health wine improving the health care of sleep obstacle, including following raw material:20 parts of honeysuckle organic acid, Poria 12 parts of polysaccharide, 16 parts of Semen Nelumbinis polyphenol, the white wine of balance of 13%vol, totally 1000 parts.
Preparation method:The white wine of honeysuckle organic acid, pachyman, Semen Nelumbinis polyphenol and 12%vol is placed in allotment In tank, after stirring and dissolving is uniform, obtain mixed liquor;Mixed liquor stands 2 days;Using nuclepore membrane filter, pore size filter is 0.45 μ m;Fill is in capacity in the burgundy bottle of 750mL.
Improve the health care of sleep obstacle efficacy test
Foundation of the present invention《Chinese medicine health care product food is developed and exploitation》Health food in (party is firm, and Xiao Ying edits) improves sleeps The method of inspection of dormancy obstructive action, with the direct sleep experiments of mice, extends the pentobarbital sodium experiment length of one's sleep, pentobarbital sodium Sub-threshold dose hypnosis is tested, and the experiment of barbital sodium Sleep latency carries out improving the health care of sleep the experiment of obstacle power test.
1st, experimental technique:Choose healthy ICR mice 40, male, 18~22g, keep free water during experiment and enter Food, feeding environment temperature is 22 ± 2 DEG C, and adaptability is tested after feeding 3-7 days.Using the health promoting wine of embodiment 5 as tested Sample, distilled water is blank control group.Mice is randomly divided into 4 groups, every group 10, and respectively embodiment 5 is high, neutralize low dosage Group, wherein high, medium and low three dosage group consumptions are respectively 40g/Kg, 20g/Kg, 10g/Kg, and blank control group gives same volume Distilled water, each dosage 0.2mL/10g, daily gavage once, continuous 30d.
2nd, experimental result
2.1 direct sleep experiments, after mice gives sample, observe mice active situation in 60min, each group mouse stomach Sleep phenomenon does not occur afterwards, result as shown in table 1, illustrates that the health promoting wine of the embodiment of the present invention 5 does not have direct syngignoscism.
The 2.2 prolongation pentobarbital sodium hypnosis time experiment embodiment of the present invention 5 are low, middle dose group can significantly extend mice and sleep The dormancy time, there is significant difference (p compared with matched group<0.05), high dose group and matched group there was no significant difference (p< 0.05), the results are shown in Table 2.
Table 2 extends the pentobarbital sodium experiment length of one's sleep
Note:* compare with matched group, p<0.05.
2.3 pentobarbital sodium sub-threshold lull dosage experiments
The mice sleep incidence rate of the basic, normal, high dosage group of the embodiment of the present invention 5 is compared with blank control group, all has notable Sex differernce (p<0.05), the results are shown in Table 3.
Table 3 pentobarbital sodium sub-threshold lull dosage experimental result
Note:* compare with matched group, p<0.05.
The 2.4 barbital sodium sleep latency experiment basic, normal, high dosage group mice sleep shorter latencies of the embodiment of the present invention 5, Compare with blank control group and all have significant difference (p<0.05), the results are shown in Table 4.
Table 4 barbital sodium Sleep latency experimental result
Note:* compare with matched group, p<0.05.
3 conclusions:The present invention improves the health care of sleep in obstacle Efficacy experiments, and the direct sleep experiments result of mice is negative, and prolongs The experiment length of one's sleep of long pentobarbital sodium, pentobarbital sodium sub-threshold dose hypnosis experiment, barbital sodium Sleep latency experiment knot Fruit is the positive, and according to function of health food touchstone, health wine set of the present invention is significantly improved effect of sleep disorder.
Embodiment described above is only better embodiment of the present invention, all without prejudice to the principle of the invention, on present invention basis On carry out substitute equivalents, simple superposition, belong to protection scope of the present invention.

Claims (9)

1. a kind of Female health wine improving the health care of sleep obstacle is it is characterised in that include following raw material:
2. a kind of Female health wine improving the health care of sleep obstacle according to claim 1 is it is characterised in that include following weight Part raw material:
3. a kind of Female health wine improving the health care of sleep obstacle according to claim 2 is it is characterised in that include following weight Part raw material:
4. a kind of Female health wine improving the health care of sleep obstacle according to any one of claim 1-3 is it is characterised in that include Following raw material:
5. a kind of Female health wine improving the health care of sleep obstacle according to any one of claim 1-3 is it is characterised in that described The weight part ratio of honeysuckle organic acid, pachyman and Semen Nelumbinis polyphenol is:10-28:5-18:8-20.
6. a kind of Female health wine improving the health care of sleep according to claim 5 is it is characterised in that described Flos Lonicerae is organic The weight part ratio of acid, pachyman and Semen Nelumbinis polyphenol is 15-25:8-15:10-18.
7. a kind of Female health wine improving the health care of sleep obstacle according to any one of claim 1-3 is it is characterised in that described Wine is white wine.
8. a kind of Female health wine improving the health care of sleep obstacle according to claim 7 is it is characterised in that described white wine Alcohol degree is 12-14%vol.
9. a kind of Female health wine improving the health care of sleep obstacle according to any one of right 1-3 is it is characterised in that described gold silver Flower its preservative of organic acid effect.
CN201611182683.2A 2016-12-20 2016-12-20 Female healthcare wine for alleviating sleep disorders Pending CN106398936A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110878243A (en) * 2019-12-19 2020-03-13 北京百利生葡萄酒业有限公司 Peony grape wine

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102911831A (en) * 2011-08-03 2013-02-06 葛双铭 Tonic grape wine
CN103720987A (en) * 2012-10-11 2014-04-16 钱宝明 Lotus seed health care wine for spleen insufficiency and diarrhea
CN104130891A (en) * 2014-06-27 2014-11-05 苏州颉田农业开发有限公司 Manufacturing process for poria cocos grape wine
CN105331478A (en) * 2015-11-26 2016-02-17 阜阳市金湖丰农业科技有限公司 Anti-oxidation brandy

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102911831A (en) * 2011-08-03 2013-02-06 葛双铭 Tonic grape wine
CN103720987A (en) * 2012-10-11 2014-04-16 钱宝明 Lotus seed health care wine for spleen insufficiency and diarrhea
CN104130891A (en) * 2014-06-27 2014-11-05 苏州颉田农业开发有限公司 Manufacturing process for poria cocos grape wine
CN105331478A (en) * 2015-11-26 2016-02-17 阜阳市金湖丰农业科技有限公司 Anti-oxidation brandy

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王金丹: "金银花中绿原酸的研究进展", 《农业科技与装备》 *
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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110878243A (en) * 2019-12-19 2020-03-13 北京百利生葡萄酒业有限公司 Peony grape wine

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Application publication date: 20170215