CN106387350A - Preparation method of compound feed additive by using plant extracts to replace antibiotics - Google Patents
Preparation method of compound feed additive by using plant extracts to replace antibiotics Download PDFInfo
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- CN106387350A CN106387350A CN201610871261.XA CN201610871261A CN106387350A CN 106387350 A CN106387350 A CN 106387350A CN 201610871261 A CN201610871261 A CN 201610871261A CN 106387350 A CN106387350 A CN 106387350A
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Abstract
The present invention discloses a preparation method of a compound feed additive by using plant extracts to replace antibiotics, belonging to the technical field of feed additives. The preparation method of the compound feed additive by using the plant extracts to replace the antibiotics comprises the following steps: S1: raw material selecting; S2: squeezing and filtering; S3: needed juice obtaining; S4: additive combining; S5: heating and stirring; and S6: drying and molding. The preparation method of the compound feed additive by using the plant extracts to replace the antibiotics uses the plant extracts as the compound feed additive to replace the antibiotics, reduces the amounts of chemical drug abuses, and avoids damages to animals due to excessive drugs. The plant extracts are green and natural, and the use of the plant extracts lowers costs and saves money.
Description
Technical field
The present invention relates to field of feed additive technology, specially a kind of mixed feed of plant extract substitute antibiotics adds
Plus the preparation method of agent.
Background technology
Antibiotic is applied widely as feed addictive, in prevention Animal diseases, promotes the aspects such as growth of animal to do
Gone out tremendous contribution, but in recent years, antibiotic in a large amount of uses of livestock-raising industry, particularly unscientific abuse so that
Bacterial drug resistance increases.In addition, medicament residue causes animal production safety problem also to be closed by entirely national, whole industry
Note.With the continuous improvement recognizing for antibiotic potential risk factor, more and more country takes measures to limit and even prohibits
The only application of antibioticses additive, scholars are sought for studying the substitute of antibiotic, and wherein plant extracts is at some
European countries have been used widely, and effect is fairly obvious, the research to plant extracts for some scholars domestic in recent years
Also constantly strengthen, such as Chinese Patent Application No. is that a kind of 201410381748.0 plant extract feeds of substitute antibiotics add
Plus agent, belong to feed additive field.This feed addictive is made up of cinnamic acid, anise alcohol, curcumin and appropriate carrier, and this replaces
Plant extract feed additive for antibiotic is relatively costly, for this reason, we have proposed a kind of plant extract substitute antibiotics
Composite feed additive preparation method.
Content of the invention
It is an object of the invention to provide a kind of preparation method of the composite feed additive of plant extract substitute antibiotics,
With solve above-mentioned background technology in propose antibiotic livestock-raising industry a large amount of uses, particularly unscientific abuse,
Make the problem that bacterial drug resistance increases.
For achieving the above object, the present invention provides following technical scheme：A kind of the compound of plant extract substitute antibiotics is raised
The preparation method of feed additives, the step of the composite feed additive preparation method of this plant extract substitute antibiotics is as follows：
S1：Choose raw material：Raw material are respectively：The Radix Astragali, Radix Isatidis, glutinous rehmannia, and the Radix Astragali：Radix Isatidis：Glutinous rehmannia=4:3:3
And by above materials classification, Preservation Treatment；
S2：Squeeze the juice, filter：Raw material after Preservation Treatment in step S1 separately are carried out squeezing the juice operation, the juice after squeezing the juice
Liquid filters through sieves and is retained separately；
S3：Juice needed for acquisition：Juice after preserving in step S2 is obtained, and juice is stood, after filtering off precipitation, make
Respectively the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice are carried out with dissolving absorption with organic solvent, and absorption juice is organic molten
Agent carries out Multi-layer technology, and the juice after extraction adopts way of distillation distillation to obtain；
S4：Proportioning additive：The Radix Astragali obtaining in step S3, Radix Isatidis and glutinous rehmannia raw material juice are placed in clean beaker
In, add carrier in beaker, the addition quality of carrier is three times of the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice gross mass,
Add vitamin E and vitamin C in raw material juice, and vitamin E：Vitamin C：The Radix Astragali=1:1:200；
S5：Heating stirring：There is in obtaining step S4 carrier and the beaker of the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice,
It is stirred using stirring rod after adding carrier, the raw material after stirring is taken out and is placed in drying receptacle, drying receptacle is heated
And stir, the material left after stirring is cooled to normal temperature；
S6：It is dried, be molded：The compound being cooled to normal temperature in step S5 is obtained, the compound after acquisition is placed in mould
In, the mould after assembling is placed in interior is dried, dried compound packaging is placed in preserving in freezer.
Preferably, the operation of squeezing the juice in described step S2 adopts Domestic fruit extractor, and mixing speed turns every point for 500-600
Clock.
Preferably, filter in described step S2 and filter initially with rove, filtering times are that the liquid after filtration is adopted twice
Filtered with spun yarn.
Preferably, the carrier in described step S4 is specially protein carrier.
Preferably, the stirring in described step S5 adopts hand operated mixing, stirs to the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice
Liquid is mixed completely with carrier, during stirring, beaker is heated, and heating-up temperature is 60-70 degree Celsius.
Preferably, indoor temperature is dried in described step S6 and is 50-60 degree Celsius, drying time is 4-5 hour.
Preferably, in described step S5, the temperature of freezer is 0-5 degree Celsius.
Compared with prior art, the invention has the beneficial effects as follows：The mixed feed of this plant extract substitute antibiotics adds
The preparation method of agent, is used plant extraction liquid substitute antibiotics as composite feed additive, decreases chemicals abuse
Situation, it is to avoid excessively multipair animal damages medicine, using plant extraction liquid green sky heat, reduces cost, saving fund.
Brief description
Fig. 1 is preparation method flow chart of the present invention.
Specific embodiment
Below in conjunction with the accompanying drawing in the embodiment of the present invention, the technical scheme in the embodiment of the present invention is carried out clear, complete
Site preparation description is it is clear that described embodiment is only a part of embodiment of the present invention, rather than whole embodiments.It is based on
Embodiment in the present invention, it is every other that those of ordinary skill in the art are obtained under the premise of not making creative work
Embodiment, broadly falls into the scope of protection of the invention.
Embodiment one
A kind of preparation method of the composite feed additive of plant extract substitute antibiotics, this plant extract substitute antibiotics
Composite feed additive preparation method step as follows：
S1：Choose raw material：Raw material are respectively：The Radix Astragali, Radix Isatidis, glutinous rehmannia, and the Radix Astragali：Radix Isatidis：Glutinous rehmannia=4:3:3
And by above materials classification, Preservation Treatment；
S2：Squeeze the juice, filter：Raw material after Preservation Treatment in step S1 separately are carried out squeezing the juice operation, and operation of squeezing the juice is adopted
With Domestic fruit extractor, mixing speed is 500 rpms, and the juice after squeezing the juice filters through sieves and is retained separately, and filters
Filter initially with rove, filtering times are twice, the liquid after filtration adopts spun yarn to filter；
S3：Juice needed for acquisition：Juice after preserving in step S2 is obtained, and juice is stood, after filtering off precipitation, make
Respectively the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice are carried out with dissolving absorption with organic solvent, and absorption juice is organic molten
Agent carries out Multi-layer technology, and the juice after extraction adopts way of distillation distillation to obtain；
S4：Proportioning additive：The Radix Astragali obtaining in step S3, Radix Isatidis and glutinous rehmannia raw material juice are placed in clean beaker
In, add carrier in beaker, carrier is specially protein carrier, the addition quality of carrier is the Radix Astragali, Radix Isatidis and ground xanthan
Three times of material juice gross mass, add vitamin E and vitamin C in raw material juice, and vitamin E：Vitamin C：Yellow
Stilbene=1:1:200；
S5：Heating stirring：There is in obtaining step S4 carrier and the beaker of the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice,
It is stirred using stirring rod after adding carrier, stirring adopts hand operated mixing, stirs to the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice
Liquid is mixed completely with carrier, during stirring, beaker is heated, and heating-up temperature is 60 degrees Celsius, the raw material taking-up after stirring is placed in dry
In dry container, drying receptacle is heated and stirs, the material left after stirring is cooled to normal temperature；
S6：It is dried, be molded：The compound being cooled to normal temperature in step S5 is obtained, the compound after acquisition is placed in mould
In, the mould after assembling is placed in interior is dried, indoor temperature is dried and is 50 degrees Celsius, drying time is 4 hours, after being dried
Compound packaging be placed in preserving in freezer, the temperature of freezer is 0 degree Celsius.
Embodiment two
A kind of preparation method of the composite feed additive of plant extract substitute antibiotics, this plant extract substitute antibiotics
Composite feed additive preparation method step as follows：
S1：Choose raw material：Raw material are respectively：The Radix Astragali, Radix Isatidis, glutinous rehmannia, and the Radix Astragali：Radix Isatidis：Glutinous rehmannia=4:3:3
And by above materials classification, Preservation Treatment；
S2：Squeeze the juice, filter：Raw material after Preservation Treatment in step S1 separately are carried out squeezing the juice operation, and operation of squeezing the juice is adopted
With Domestic fruit extractor, mixing speed is 550 rpms, and the juice after squeezing the juice filters through sieves and is retained separately, and filters
Filter initially with rove, filtering times are twice, the liquid after filtration adopts spun yarn to filter；
S3：Juice needed for acquisition：Juice after preserving in step S2 is obtained, and juice is stood, after filtering off precipitation, make
Respectively the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice are carried out with dissolving absorption with organic solvent, and absorption juice is organic molten
Agent carries out Multi-layer technology, and the juice after extraction adopts way of distillation distillation to obtain；
S4：Proportioning additive：The Radix Astragali obtaining in step S3, Radix Isatidis and glutinous rehmannia raw material juice are placed in clean beaker
In, add carrier in beaker, carrier is specially protein carrier, the addition quality of carrier is the Radix Astragali, Radix Isatidis and ground xanthan
Three times of material juice gross mass, add vitamin E and vitamin C in raw material juice, and vitamin E：Vitamin C：Yellow
Stilbene=1:1:200；
S5：Heating stirring：There is in obtaining step S4 carrier and the beaker of the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice,
It is stirred using stirring rod after adding carrier, stirring adopts hand operated mixing, stirs to the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice
Liquid is mixed completely with carrier, during stirring, beaker is heated, and heating-up temperature is 65 degrees Celsius, the raw material taking-up after stirring is placed in dry
In dry container, drying receptacle is heated and stirs, the material left after stirring is cooled to normal temperature；
S6：It is dried, be molded：The compound being cooled to normal temperature in step S5 is obtained, the compound after acquisition is placed in mould
In, the mould after assembling is placed in interior is dried, indoor temperature is dried and is 55 degrees Celsius, drying time is 4.5 hours, is dried
Compound packaging afterwards is placed in preserving in freezer, and the temperature of freezer is 2.5 degrees Celsius.
Embodiment three
A kind of preparation method of the composite feed additive of plant extract substitute antibiotics, this plant extract substitute antibiotics
Composite feed additive preparation method step as follows：
S1：Choose raw material：Raw material are respectively：The Radix Astragali, Radix Isatidis, glutinous rehmannia, and the Radix Astragali：Radix Isatidis：Glutinous rehmannia=4:3:3
And by above materials classification, Preservation Treatment；
S2：Squeeze the juice, filter：Raw material after Preservation Treatment in step S1 separately are carried out squeezing the juice operation, and operation of squeezing the juice is adopted
With Domestic fruit extractor, mixing speed is 600 rpms, and the juice after squeezing the juice filters through sieves and is retained separately, and filters
Filter initially with rove, filtering times are twice, the liquid after filtration adopts spun yarn to filter；
S3：Juice needed for acquisition：Juice after preserving in step S2 is obtained, and juice is stood, after filtering off precipitation, make
Respectively the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice are carried out with dissolving absorption with organic solvent, and absorption juice is organic molten
Agent carries out Multi-layer technology, and the juice after extraction adopts way of distillation distillation to obtain；
S4：Proportioning additive：The Radix Astragali obtaining in step S3, Radix Isatidis and glutinous rehmannia raw material juice are placed in clean beaker
In, add carrier in beaker, carrier is specially protein carrier, the addition quality of carrier is the Radix Astragali, Radix Isatidis and ground xanthan
Three times of material juice gross mass, add vitamin E and vitamin C in raw material juice, and vitamin E：Vitamin C：Yellow
Stilbene=1:1:200；
S5：Heating stirring：There is in obtaining step S4 carrier and the beaker of the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice,
It is stirred using stirring rod after adding carrier, stirring adopts hand operated mixing, stirs to the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice
Liquid is mixed completely with carrier, during stirring, beaker is heated, and heating-up temperature is 70 degrees Celsius, the raw material taking-up after stirring is placed in dry
In dry container, drying receptacle is heated and stirs, the material left after stirring is cooled to normal temperature；
S6：It is dried, be molded：The compound being cooled to normal temperature in step S5 is obtained, the compound after acquisition is placed in mould
In, the mould after assembling is placed in interior is dried, indoor temperature is dried and is 60 degrees Celsius, drying time is 5 hours, after being dried
Compound packaging be placed in preserving in freezer, the temperature of freezer is 5 degrees Celsius.
Experimental result according to embodiment one, two, three is summarized and is drawn：Optimum implementation is embodiment two.
Although an embodiment of the present invention has been shown and described, for the ordinary skill in the art, permissible
Understand and can carry out multiple changes, modification, replacement to these embodiments without departing from the principles and spirit of the present invention
And modification, the scope of the present invention be defined by the appended.
Claims (7)
1. a kind of preparation method of the composite feed additive of plant extract substitute antibiotics it is characterised in that：This plant extract
The step of the composite feed additive preparation method of substitute antibiotics is as follows：
S1：Choose raw material：Raw material are respectively：The Radix Astragali, Radix Isatidis, glutinous rehmannia, and the Radix Astragali：Radix Isatidis：Glutinous rehmannia=4:3:3 and will
Above materials classification, Preservation Treatment；
S2：Squeeze the juice, filter：Raw material after Preservation Treatment in step S1 separately are carried out squeezing the juice operation, the juice warp after squeezing the juice
Cross sieves to filter and be retained separately；
S3：Juice needed for acquisition：Juice after preserving in step S2 obtains, and juice is stood, after filtering off precipitation, using having
Machine solvent carries out dissolving absorption respectively to the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice, and the organic solvent of absorption juice is entered
Row Multi-layer technology, the juice after extraction adopts way of distillation distillation to obtain；
S4：Proportioning additive：The Radix Astragali obtaining in step S3, Radix Isatidis and glutinous rehmannia raw material juice are placed in clean beaker,
Add carrier in beaker, the addition quality of carrier is three times of the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice gross mass, Xiang Yuan
Vitamin E and vitamin C is added in material juice, and vitamin E：Vitamin C：The Radix Astragali=1:1:200；
S5：Heating stirring：There are in obtaining step S4 carrier and the Radix Astragali, Radix Isatidis, glutinous rehmannia, vitamin E and vitamin C raw material
The beaker of juice, is stirred using stirring rod after adding carrier, the raw material after stirring is taken out and is placed in drying receptacle, to dry
Dry container heats and stirs, and the material left after stirring is cooled to normal temperature；
S6：It is dried, be molded：The compound being cooled to normal temperature in step S5 is obtained, the compound after acquisition is placed in mould, will
Mould after assembling is placed in and interior is dried, and dried compound packaging is placed in preserving in freezer.
2. the preparation method of the composite feed additive of a kind of plant extract substitute antibiotics according to claim 1, its
It is characterised by：Operation of squeezing the juice in described step S2 adopts Domestic fruit extractor, and mixing speed is 500-600 rpm.
3. the preparation method of the composite feed additive of a kind of plant extract substitute antibiotics according to claim 1, its
It is characterised by：Filter in described step S2 and filter initially with rove, filtering times are that the liquid after filtration adopts spun yarn twice
Filter.
4. the preparation method of the composite feed additive of a kind of plant extract substitute antibiotics according to claim 1, its
It is characterised by：Carrier in described step S4 is specially protein carrier.
5. the preparation method of the composite feed additive of a kind of plant extract substitute antibiotics according to claim 1, its
It is characterised by：Stirring in described step S5 adopts hand operated mixing, stirs to the Radix Astragali, Radix Isatidis and glutinous rehmannia raw material juice and load
Body mixes completely, during stirring, beaker is heated, and heating-up temperature is 60-70 degree Celsius.
6. the preparation method of the composite feed additive of a kind of plant extract substitute antibiotics according to claim 1, its
It is characterised by：Indoor temperature is dried in described step S6 and is 50-60 degree Celsius, drying time is 4-5 hour.
7. the preparation method of the composite feed additive of a kind of plant extract substitute antibiotics according to claim 1, its
It is characterised by：In described step S5, the temperature of freezer is 0-5 degree Celsius.
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| CN201610871261.XA CN106387350A (en) | 2016-09-30 | 2016-09-30 | Preparation method of compound feed additive by using plant extracts to replace antibiotics |
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| CN1394634A (en) * | 2002-08-26 | 2003-02-05 | 河北万岁制药集团有限公司 | Preparation process of fresh isatis root juice |
| CN102172265A (en) * | 2011-04-02 | 2011-09-07 | 湖南广安生物技术股份有限公司 | Feed additive for improving stress resistance, meat color and meat quality of grown fattening pig and application thereof |
| CN102524584A (en) * | 2012-01-20 | 2012-07-04 | 漳州双胞胎饲料有限公司 | Composite pig feed additive for effectively preventing edema of pigs |
| CN103892049A (en) * | 2014-04-02 | 2014-07-02 | 北京康华远景科技有限公司 | Plant feed additive for preventing porcine diarrhea and preparation method |
| CN105641031A (en) * | 2014-12-02 | 2016-06-08 | 北京大北农动物保健科技有限责任公司 | Compound pharmaceutical composition for strengthening body resistance and removing toxin, use and feed thereof |
-
2016
- 2016-09-30 CN CN201610871261.XA patent/CN106387350A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1394634A (en) * | 2002-08-26 | 2003-02-05 | 河北万岁制药集团有限公司 | Preparation process of fresh isatis root juice |
| CN102172265A (en) * | 2011-04-02 | 2011-09-07 | 湖南广安生物技术股份有限公司 | Feed additive for improving stress resistance, meat color and meat quality of grown fattening pig and application thereof |
| CN102524584A (en) * | 2012-01-20 | 2012-07-04 | 漳州双胞胎饲料有限公司 | Composite pig feed additive for effectively preventing edema of pigs |
| CN103892049A (en) * | 2014-04-02 | 2014-07-02 | 北京康华远景科技有限公司 | Plant feed additive for preventing porcine diarrhea and preparation method |
| CN105641031A (en) * | 2014-12-02 | 2016-06-08 | 北京大北农动物保健科技有限责任公司 | Compound pharmaceutical composition for strengthening body resistance and removing toxin, use and feed thereof |
Non-Patent Citations (1)
| Title |
|---|
| 陈功锡等: "《湘西药用植物资源开发与可持续利用》", 31 May 2015, 西南交通大学出版社 * |
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