CN106377639A - 一种用于治疗骨折及扭伤的外用中药膏剂及其制备方法 - Google Patents
一种用于治疗骨折及扭伤的外用中药膏剂及其制备方法 Download PDFInfo
- Publication number
- CN106377639A CN106377639A CN201610887648.4A CN201610887648A CN106377639A CN 106377639 A CN106377639 A CN 106377639A CN 201610887648 A CN201610887648 A CN 201610887648A CN 106377639 A CN106377639 A CN 106377639A
- Authority
- CN
- China
- Prior art keywords
- parts
- radix
- traditional chinese
- cortex
- raw material
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/889—Arecaceae, Palmae or Palmaceae (Palm family), e.g. date or coconut palm or palmetto
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/36—Skin; Hair; Nails; Sebaceous glands; Cerumen; Epidermis; Epithelial cells; Keratinocytes; Langerhans cells; Ectodermal cells
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/583—Snakes; Lizards, e.g. chameleons
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/616—Echinodermata, e.g. starfish, sea cucumbers or sea urchins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/21—Amaranthaceae (Amaranth family), e.g. pigweed, rockwort or globe amaranth
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
- A61K36/258—Panax (ginseng)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/27—Asclepiadaceae (Milkweed family), e.g. hoya
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/35—Caprifoliaceae (Honeysuckle family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/36—Caryophyllaceae (Pink family), e.g. babysbreath or soapwort
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/39—Convolvulaceae (Morning-glory family), e.g. bindweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/42—Cucurbitaceae (Cucumber family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/487—Psoralea
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
- A61K36/537—Salvia (sage)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/56—Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/57—Magnoliaceae (Magnolia family)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/88—Liliopsida (monocotyledons)
- A61K36/896—Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
- A61K47/30—Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
- A61K47/36—Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/50—Methods involving additional extraction steps
- A61K2236/51—Concentration or drying of the extract, e.g. Lyophilisation, freeze-drying or spray-drying
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Epidemiology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Botany (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Alternative & Traditional Medicine (AREA)
- Zoology (AREA)
- Cell Biology (AREA)
- Dermatology (AREA)
- Biomedical Technology (AREA)
- Developmental Biology & Embryology (AREA)
- Immunology (AREA)
- Virology (AREA)
- Inorganic Chemistry (AREA)
- Marine Sciences & Fisheries (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
本发明公开了一种用于治疗骨折及扭伤的外用中药膏剂及其制备方法,由藏红花、土贝母、鬼针草、金铁锁、丁公藤、马钱子、地枫皮、滴血根、徐长卿、丹参、三七、香加皮、走马箭、半枫荷、银线草、风寒草、沙棘、独活、补骨脂、马比木、海参、牛膝、何首乌、血竭、穿山甲、乌梢蛇和淀粉制备而成,将各原料分别洗净晾干,粉碎过筛,按配比混合,加水煎煮两次,合并滤液后加淀粉混合,减压浓缩至稠膏,降至室温,即可。本发明采用中药制成,使用方便,用药后无副作用,缩短术后恢复时间,具有活血止痛、续筋健骨的作用,安全可靠,疗程短,疗效快,效果好,有利于伤口愈合以及减轻疼痛症状。
Description
技术领域
本发明涉及中药技术领域,具体是一种用于治疗骨折及扭伤的外用中药膏剂及其制备方法。
背景技术
人们在进行高强度的肢体运动时,容易在腰部、膝、肩、肘、颈、腕关节和躁关节部位发生扭挫筋伤。扭挫伤通常是由肌肉、筋膜、韧带、软骨和关节超负荷运动或用力过猛而引起的,症状表现为红肿癖血或伴随外皮出血,同时也往往伴随着各种并发炎症。
无论是偶发性的筋骨损伤,还是外感性的骨科炎症,以及骨科术后的愈合期,病患都需要承受剧烈的疼痛、肢体痉挛等痛苦。针对以上诸种病痛的治疗,医院大多采用止痛药、广谱杀菌消炎药等方法进行处理。这种处理方法往往缺乏针对性,未能从引起炎症的根源入手,也不能加快伤口的愈合,停药后仍无法减轻患者的疼痛,见效迟缓,治疗时间较长,对风湿性的骨科炎症更是无能为力。
发明内容
本发明的目的在于提供一种用于治疗骨折及扭伤的外用中药膏剂及其制备方法,以解决上述背景技术中提出的问题。
为实现上述目的,本发明提供如下技术方案:
一种用于治疗骨折及扭伤的外用中药膏剂,由以下重量份的原料制备而成:藏红花12~16份,土贝母10~14份,鬼针草18~24份,金铁锁16~18份,丁公藤11~15份,马钱子12~16份,地枫皮13~17份,滴血根8~12份,徐长卿6~8份,丹参6~8份,三七15~19份,香加皮11~13份,走马箭9~11份,半枫荷9~13份,银线草6~10份,风寒草6~8份,沙棘10~16份,独活12~16份,补骨脂10~14份,马比木13~15份,海参10~14份,牛膝5~9份,何首乌8~12份,血竭4~6份,穿山甲4~6份,乌梢蛇3~5份,淀粉30~40份。
作为本发明进一步的方案:由以下重量份的原料制备而成:藏红花14份,土贝母12份,鬼针草21份,金铁锁17份,丁公藤13份,马钱子14份,地枫皮15份,滴血根10份,徐长卿7份,丹参7份,三七17份,香加皮12份,走马箭10份,半枫荷11份,银线草8份,风寒草7份,沙棘13份,独活14份,补骨脂12份,马比木14份,海参12份,牛膝7份,何首乌10份,血竭5份,穿山甲5份,乌梢蛇4份,淀粉35份。
一种所述的用于治疗骨折及扭伤的外用中药膏剂的制备方法,具体步骤如下:
(1)将上述中药原料分别洗净晾干,然后粉碎至60~80目,过筛后,备用;
(2)将上述粉碎后的原料按配比混合,加入原料总重量12~14倍的水,并在60~64℃下浸泡2~3h,加热煎煮2~3h,过滤,滤液备用;滤渣中加入滤渣质量8~10倍的水,加热煮沸2~3h,过滤,滤液备用;合并两次滤液;
(3)将淀粉加入合并的滤液中,加热煮沸20~24min,冷却,在50~56℃下减压浓缩成相对密度为1.30~1.40的稠膏,冷却至室温,紫外线照射杀菌,即可。
与现有技术相比,本发明的有益效果是:
本发明采用中药制成,使用方便,用药后无副作用,缩短术后恢复时间,具有活血止痛、续筋健骨的作用,安全可靠,疗程短,疗效快,效果好,有利于伤口愈合以及减轻疼痛症状。
具体实施方式
下面将结合本发明实施例,对本发明实施例中的技术方案进行清楚、完整地描述,显然,所描述的实施例仅仅是本发明一部分实施例,而不是全部的实施例。基于本发明中的实施例,本领域普通技术人员在没有做出创造性劳动前提下所获得的所有其他实施例,都属于本发明保护的范围。
实施例1
用于治疗骨折及扭伤的外用中药膏剂,由以下重量的原料制备而成:藏红花12g,土贝母14g,鬼针草18g,金铁锁18g,丁公藤11g,马钱子16g,地枫皮13g,滴血根12g,徐长卿6g,丹参8g,三七15g,香加皮13g,走马箭9g,半枫荷13g,银线草6g,风寒草8g,沙棘10g,独活16g,补骨脂10g,马比木15g,海参10g,牛膝9g,何首乌8g,血竭6g,穿山甲4g,乌梢蛇5g,淀粉30g。
上述中药制剂的制备步骤如下:
(1)将上述中药原料分别洗净晾干,然后粉碎至60目,过筛后,备用;
(2)将上述粉碎后的原料按配比混合,加入原料总重量12倍的水,并在60℃下浸泡2h,加热煎煮2h,过滤,滤液备用;滤渣中加入滤渣质量8倍的水,加热煮沸2h,过滤,滤液备用;合并两次滤液;
(3)将淀粉加入合并的滤液中,加热煮沸20min,冷却,在50℃下减压浓缩成相对密度为1.30~1.40的稠膏,冷却至室温,紫外线照射杀菌,即可。
实施例2
用于治疗骨折及扭伤的外用中药膏剂,由以下重量的原料制备而成:藏红花14g,土贝母12g,鬼针草21g,金铁锁17g,丁公藤13g,马钱子14g,地枫皮15g,滴血根10g,徐长卿7g,丹参7g,三七17g,香加皮12g,走马箭10g,半枫荷11g,银线草8g,风寒草7g,沙棘13g,独活14g,补骨脂12g,马比木14g,海参12g,牛膝7g,何首乌10g,血竭5g,穿山甲5g,乌梢蛇4g,淀粉35g。
上述中药制剂的制备步骤如下:
(1)将上述中药原料分别洗净晾干,然后粉碎至70目,过筛后,备用;
(2)将上述粉碎后的原料按配比混合,加入原料总重量13倍的水,并在62℃下浸泡2.5h,加热煎煮2.5min,过滤,滤液备用;滤渣中加入滤渣质量9倍的水,加热煮沸2.5min,过滤,滤液备用;合并两次滤液;
(3)将淀粉加入合并的滤液中,加热煮沸22min,冷却,在53℃下减压浓缩成相对密度为1.30~1.40的稠膏,冷却至室温,紫外线照射杀菌,即可。
实施例3
用于治疗骨折及扭伤的外用中药膏剂,由以下重量的原料制备而成:藏红花16g,土贝母10g,鬼针草24g,金铁锁16g,丁公藤15g,马钱子12g,地枫皮17g,滴血根8g,徐长卿8g,丹参6g,三七19g,香加皮11g,走马箭11g,半枫荷9g,银线草10g,风寒草6g,沙棘16g,独活12g,补骨脂14g,马比木13g,海参14g,牛膝5g,何首乌12g,血竭4g,穿山甲6g,乌梢蛇3g,淀粉40g。
上述中药制剂的制备步骤如下:
(1)将上述中药原料分别洗净晾干,然后粉碎至80目,过筛后,备用;
(2)将上述粉碎后的原料按配比混合,加入原料总重量14倍的水,并在64℃下浸泡3h,加热煎煮3h,过滤,滤液备用;滤渣中加入滤渣质量10倍的水,加热煮沸3h,过滤,滤液备用;合并两次滤液;
(3)将淀粉加入合并的滤液中,加热煮沸24min,冷却,在56℃下减压浓缩成相对密度为1.30~1.40的稠膏,冷却至室温,紫外线照射杀菌,即可。
治疗效果:
本发明中药组合物通过随机抽取200例患者中,男80例,女70例,年龄最小16岁,最大80岁,病程最短的10天,最长50天。以及对照组的采用现有骨折外敷药治疗50例患者,男30例,女20例,年龄最大60岁,最小20岁,病程最短7天,最长3年。患者均具有典型的临床症状和体征。
将制得的药膏外敷于患处,每次一贴,两日更换,3天一个疗程。根据患者病情轻重计算治疗时间,轻度患者贴1-3疗程左右,重病患者连贴3-10疗程即可痊愈。
疗效判定标准
痊愈:骨折处以及筋骨损伤处疼痛明显缓解,红肿消失,疲血消解,肌肉紧张、痉挛症状缓解、消失,能正常活动;骨科炎症患者疼痛明显缓解,红肿部位变小、明显缓解,肌肉酸痛无力症状明显缓解。
好转:骨折处以及筋骨损伤处疼痛有所缓解;骨科炎症患者疼痛有所缓解。
无效:骨折处伤口、疼痛以及损伤的痊愈时间不随用药而发生改变。
组别 | 例数 | 痊愈 | 好转 | 无效 | 有效率 |
治疗组 | 200 | 190 | 10 | 0 | 100% |
对比组 | 50 | 20 | 20 | 10 | 80% |
典型案例:
1、连某,男,39岁,因外伤导致胫腓骨骨干骨折,后经手术复位,之后创伤处一直疼痛难忍,术后15天采用本发明膏剂外敷于患处,使用2个疗程后,患处疼痛减轻,继续使用3个疗程,可支撑拐杖行走,行走时患处有疼痛感,继续服用2个疗程,患处基本无疼痛感,可脱离拐杖支撑行走,痊愈后患处无任何后遗症。
2、时某,女,20岁,因工导致胳膊骨折,术后复位,住院治疗3天后出院回家,之后通过止疼片止痛,停药后疼痛难忍,后使用本发明膏剂进行治疗,1个疗程后疼痛减轻,后续使用2个疗程,胳膊可做小范围活动,再使用两个疗程,可正常生活,骨折处愈合良好。
3、刘某,男,45岁,农民,常年患有风湿性关节炎,病情时有反复,发作起来疼痛难忍、彻夜难眠,遇到阴雨天气全身骨骼如裂,痛不欲生,来本院问诊时,发现多数骨节有水肿现象,膝关节部位肌肉萎缩,全身无力感严重,以本发明膏剂敷于患处后以绷带绑扎,正常在田间劳作,每2日换药一次,3个疗程9天后复诊,明显感到敷药处发热,但疼痛感未见减少。继续敷用,第6个疗程结束,疼痛感完全消失,能正常劳动,风湿性关节炎基本痊愈。
对于本领域技术人员而言,显然本发明不限于上述示范性实施例的细节,而且在不背离本发明的精神或基本特征的情况下,能够以其他的具体形式实现本发明。因此,无论从哪一点来看,均应将实施例看作是示范性的,而且是非限制性的,本发明的范围由所附权利要求而不是上述说明限定,因此旨在将落在权利要求的等同要件的含义和范围内的所有变化囊括在本发明内。
Claims (3)
1.一种用于治疗骨折及扭伤的外用中药膏剂,其特征在于,由以下重量份的原料制备而成:藏红花12~16份,土贝母10~14份,鬼针草18~24份,金铁锁16~18份,丁公藤11~15份,马钱子12~16份,地枫皮13~17份,滴血根8~12份,徐长卿6~8份,丹参6~8份,三七15~19份,香加皮11~13份,走马箭9~11份,半枫荷9~13份,银线草6~10份,风寒草6~8份,沙棘10~16份,独活12~16份,补骨脂10~14份,马比木13~15份,海参10~14份,牛膝5~9份,何首乌8~12份,血竭4~6份,穿山甲4~6份,乌梢蛇3~5份,淀粉30~40份。
2.根据权利要求1所述的用于治疗骨折及扭伤的外用中药膏剂,其特征在于,由以下重量份的原料制备而成:藏红花14份,土贝母12份,鬼针草21份,金铁锁17份,丁公藤13份,马钱子14份,地枫皮15份,滴血根10份,徐长卿7份,丹参7份,三七17份,香加皮12份,走马箭10份,半枫荷11份,银线草8份,风寒草7份,沙棘13份,独活14份,补骨脂12份,马比木14份,海参12份,牛膝7份,何首乌10份,血竭5份,穿山甲5份,乌梢蛇4份,淀粉35份。
3.一种如权利要求1或2所述的用于治疗骨折及扭伤的外用中药膏剂的制备方法,其特征在于,具体步骤如下:
(1)将上述中药原料分别洗净晾干,然后粉碎至60~80目,过筛后,备用;
(2)将上述粉碎后的原料按配比混合,加入原料总重量12~14倍的水,并在60~64℃下浸泡2~3h,加热煎煮2~3h,过滤,滤液备用;滤渣中加入滤渣质量8~10倍的水,加热煮沸2~3h,过滤,滤液备用;合并两次滤液;
(3)将淀粉加入合并的滤液中,加热煮沸20~24min,冷却,在50~56℃下减压浓缩成相对密度为1.30~1.40的稠膏,冷却至室温,紫外线照射杀菌,即可。
Priority Applications (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610887648.4A CN106377639A (zh) | 2016-10-11 | 2016-10-11 | 一种用于治疗骨折及扭伤的外用中药膏剂及其制备方法 |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN201610887648.4A CN106377639A (zh) | 2016-10-11 | 2016-10-11 | 一种用于治疗骨折及扭伤的外用中药膏剂及其制备方法 |
Publications (1)
Publication Number | Publication Date |
---|---|
CN106377639A true CN106377639A (zh) | 2017-02-08 |
Family
ID=57936139
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN201610887648.4A Pending CN106377639A (zh) | 2016-10-11 | 2016-10-11 | 一种用于治疗骨折及扭伤的外用中药膏剂及其制备方法 |
Country Status (1)
Country | Link |
---|---|
CN (1) | CN106377639A (zh) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106943585A (zh) * | 2017-05-17 | 2017-07-14 | 贵州红润生物科技有限公司 | 一种用于治疗扭伤消肿止痛的三七外用复方制剂及制备方法 |
-
2016
- 2016-10-11 CN CN201610887648.4A patent/CN106377639A/zh active Pending
Non-Patent Citations (1)
Title |
---|
屈强: "《骨伤病症》", 30 April 2016, 中国医药科技出版社 * |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN106943585A (zh) * | 2017-05-17 | 2017-07-14 | 贵州红润生物科技有限公司 | 一种用于治疗扭伤消肿止痛的三七外用复方制剂及制备方法 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
CN102988657A (zh) | 一种治疗骨折及跌打损伤的膏药及其制备方法 | |
CN105920540A (zh) | 一种活络油及其制备方法 | |
CN105982976B (zh) | 治疗骨关节疾病的骨骼渗透液及其制备方法 | |
CN101234153A (zh) | 治疗骨折的外用药物 | |
CN101361817A (zh) | 一种治疗骨筋损伤的中药制剂 | |
CN103566278B (zh) | 接骨丹 | |
CN102085283B (zh) | 一种治疗骨化性肌炎的中药 | |
CN106377639A (zh) | 一种用于治疗骨折及扭伤的外用中药膏剂及其制备方法 | |
CN102552608A (zh) | 一种治疗骨折、骨损伤的药物组合物及其制备方法和用途 | |
CN103285203B (zh) | 用于预防和治疗骨折的中药组合物及其制备方法 | |
CN105232905A (zh) | 一种治疗骨质增生的中药制剂及其制备方法 | |
CN103385985B (zh) | 一种快速接筋骨的中草药组合物 | |
CN103623350A (zh) | 一种促进骨折愈合的中药膏药 | |
CN105126062A (zh) | 一种用于治疗跌打损伤的中药组合物及其制备方法 | |
CN104524066A (zh) | 用于治疗桡骨远端骨折的接骨膏 | |
CN112755134B (zh) | 一种用于治疗骨质增生的膏药及其制备方法 | |
CN103877393A (zh) | 一种治疗创伤性膝关节滑膜炎的中药组合物及其应用 | |
CN103127344B (zh) | 治疗骨折不愈合、骨折迟缓性愈合的中药制剂及制备方法 | |
CN108186983A (zh) | 一种用于治疗风湿骨病的膏药及其制备方法 | |
CN103083602B (zh) | 一种治疗腰椎病的外用药物组合物 | |
CN105998642A (zh) | 一种髌骨骨折术后外用接骨药膏及其制备方法 | |
CN105412889A (zh) | 治疗腰椎间盘突出的中药蜜丸及其制备方法 | |
CN108888736B (zh) | 一种外用接骨续筋药及其制备方法 | |
CN104784336A (zh) | 一种治疗风湿腿痛的中药喷剂 | |
CN105233158A (zh) | 一种治疗颈椎病的中药组合物及其制备方法 |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C06 | Publication | ||
PB01 | Publication | ||
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
RJ01 | Rejection of invention patent application after publication | ||
RJ01 | Rejection of invention patent application after publication |
Application publication date: 20170208 |