CN106377604A - Antibacterial inflammation diminishing and itching relieving traditional Chinese medicine ointment and preparation method thereof - Google Patents

Abstract

The invention discloses an antibacterial inflammation diminishing and itching relieving traditional Chinese medicine ointment and a preparation method thereof. The antibacterial inflammation diminishing and itching relieving traditional Chinese medicine ointment is prepared from the following raw material components in parts by mass: 70 to 80 parts of common sage herb, 1 to 3 parts of honeysuckle flowers, 1 to 5 parts of clove bulbs, 1 to 3 parts of radix scutellariae, 1 to 5 parts of rhizoma coptidis, 1 to 6 parts of fructus forsythia, 1 to 7 parts of camphor oil, 1 to 5 parts of cortex phellodendri, 1 to 6 parts of mint oil, 1 to 4 parts of borneol, 1 to 3 parts of eucalyptus oil, 1 to 6 parts of Chinese prickly ash and 1 to 4 parts of folium artemisiae argyi. The preparation method comprises the steps of performing preparation, soaking, decoction, filtering and evaporative concentration on non-oily medicine components in the raw materials to obtain paste, and grinding the paste with the oily components to prepare the ointment. The ointment has the effects of inhibiting bacteria and diminishing inflammation, can further promote local blood circulation, achieves the effects of eliminating swelling, diminishing inflammation, easing pain and relieving itching, and is used for treating itching and pain which are caused by dermatophytosis, welling-abscess swelling, haemorrhoids, anus pain, scalp itching, eczema, mastitis, sprain and dampen, lumbago, muscular pain, arthralgia, headache and mosquito bite.

Description

Antipruritic traditional Chinese herb medicine of a kind of anti-inflammation and preparation method thereof

（One）Technical field

The present invention relates to a kind of antipruritic traditional Chinese herb medicine of anti-inflammation, particularly a kind of with vegetable Chinese herbal medicine toad grass be mainly former What material was made be mainly used to treats tinea pedis, carbuncle swells, hemorrhoid, anus swell and ache, itching of the scalp, eczema, mastitis and sprain, frustrate The human bodies such as wound, pain in the back, courbature, arthralgia, neuralgia, headache are by easily pathogenic infection and and the mosquito such as bacterium, fungi Bite traditional Chinese herb medicines of disease such as the itch pain causing and preparation method thereof, belong to field of Chinese herbal medicine technology.

（Two）Background technology

Toad grass, leaf surfaces are rough, as the skin of toad back, therefore obtain its name.Medicine name Common Sage Herb, English name Claim Common Sage Herb.Another name：Snow is shown in grass, elephant skin grass, toad grass, leprosy clam skin, wild mustard, Lai Zicao, frog grass, snow In blue or green, black purple perilla, chenopodium ambrosiodies, monkey back of the body grass, Radix Rubiae Yunnanensis, numb hen, ditch elscholtiza, expand careless, grass etc. of passing the winter, various places call is not One.

Toad grass be born in hillside, roadside, wasteland, on the wetland of river bank, height above sea level can be to 2800m.Main product Shandong, Jiangsu, Zhejiang River, Anhui, Sichuan, Hubei etc., in addition to Xinjiang, Gansu, Qinghai, Tibet, are almost distributed in the whole nation in all parts of the country overwhelming majority and save Part.Sowing time in autumn, the summer, when autumn, the flowers are in blossom, fringe is green harvesting clean and dry or using fresh herb.At ordinary times can excavate at any time clean dry or Using fresh herb.Around the house to home also can be transplanted can plant in case of need. also can receive seed and plant again.Main chemical compositions：Contain Protocatechuic acid（protocatechuic acid）, 4- hydroxyphenyl lactic acid, homoplantaginin（homoplantaginin）, Buddhist nun pool flavones Glucoside（nepetrin）, eupafolin（eupafolin）, dinatin（hispidulin）Deng.

Toad grass as a herb, with all herbal medicine.Cool in nature, bitter, pungent, have heat-clearing, removing toxic substances, detumescence, cool blood, Diuresis, dampness removing and antipruritic the effects such as, because its drug effect is notable, in the folk prescription being commonly used for curing the disease among the people, be mainly used in treating almond Body is scorching, hemoptysis of pulmonary tuberculosis, bronchitis, ascites swelling, nephritic dropsy, uterine bleeding, have blood in stool, thrombocytopenic purpura；External application is controlled Doctor's carbuncle swells, hemorrhoid, anus swell and ache, the disease such as itching of the scalp, eczema, mastitis, vaginitis, tinea pedis.There is special efficacy to cough, to throat Swell and ache, chronic bronchitis has positive effect.

Existing using method among the people mainly has following several, and existing using method among the people mainly has following several, fills Divide and show that toad grass has good anti-inflammation effect and effect.

Using method one：It is put in pot with herb that is fresh or drying and is boiled 15 minutes about with water, then with while hot with boiling The water cleaning of toad grass or fumigate patient part, cures tinea pedis in order to external application, carbuncle swells, hemorrhoid, anus swell and ache, eczema, breast The diseases such as adenositis, vaginitis.

Using method two：Fresh and tender cauline leaf with toad grass is to boil water or brews up for treating tonsillitis, lung knot Core spitting of blood, bronchitis, ascites swelling, nephritic dropsy, uterine bleeding, have blood in stool, the disease such as thrombocytopenic purpura.

Using method three：Fried with the fresh and tender cauline leaf of toad grass（Decoct）Egg is taken, and has special efficacy to cough, and throat is swollen Bitterly, chronic bronchitis has positive effect.

Although this cheap Chinese herbal medicine evident in efficacy that is seen everywhere of toad grass is widely used as curing the disease among the people Folk prescription, but never cause the enough attention of national departments concerned and regular pharmacy corporation, widely do not developed And utilization.Though among the people have use, most of ordinary peoples are very few to its cognition, and the medical value of toad grass does not obtain To fully excavating and widely using, during use, drug effect is not not fully exerted and utilizes, the range of toad grass It is not very extensive, using method is more original and single；The active ingredient of medicine is not concentrated and is extracted, and does not have medicine The packaging changed and preparation, it is not very convenient for using, and does not also use cooperatively with other Chinese herbal medicines, forms special for treating Plant unique traditional Chinese medicinal components or the patent medicine of disease.Particularly a kind of low cost, determined curative effect, carry with easy to use with leprosy clam Toad grass is principle active component, adds other auxiliary active ingredients in order to improve drug effect, is specifically used to treat tinea pedis class disease What Chinese medicine composition was made has the ointment of anti-inflammation itching-relieving action, does not also come out.

（Three）Content of the invention

The present invention in order to make up the deficiencies in the prior art, on the basis of folk prescription among the people, there is provided a kind of with toad grass herb For principle active component, it is equipped with and other several there is anti-inflammation, antiviral, antipyretic, heat-clearing and damp-drying drug, refrigerant, purging intense heat and detonicating, only The traditional Chinese herb medicine that other Chinese herbal medicines assisting effective components of effect of itching are made, various active drug compositions synergies, it is used for Improve curative effect, improve therapeutic effect, shorten therapeutic process.Main active principle is toad grass, and auxiliary active principle is gold and silver Flower, the root of large-flowered skullcap, cloves, the coptis, the capsule of weeping forsythia, camphorated oil, golden cypress, peppermint oil, borneol, volatile oil extracted from eucalyptus' leaves or twigs, Chinese prickly ash, tarragon, the matter of each raw material components Gauge number is 70～80 parts of toad grass, 1～3 part of honeysuckle, 1～5 part of cloves, 1～3 part of the root of large-flowered skullcap, 1～5 part of the coptis, the capsule of weeping forsythia 1～6 part, 1～7 part of camphorated oil, 1～5 part of golden cypress, 1～6 part of peppermint oil, 1～4 part of borneol, 1～3 part of volatile oil extracted from eucalyptus' leaves or twigs, 1～6 part of Chinese prickly ash, 1～4 part of tarragon.

The invention has the beneficial effects as follows, this traditional Chinese medicinal components composition of raw material is simple, cheap, draws materials conveniently, processing system Make process is simple, product quality is easily controlled, patent medicine is cheap, carry with easy to use, have no toxic side effect, anti-inflammation, Antiviral effect is obvious, determined curative effect, instant effect, short treating period；Contrast is used alone toad grass curative effect and becomes apparent from, and takes effect more Hurry up, the course for the treatment of is shorter.

The ointment made of this drug regimen is directly applied to human body by the easily pathogenic bacteria para-infectious illness portion such as fungi Position and by bite by mosquitos, for treating tinea pedis, carbuncle swells, hemorrhoid, anus swell and ache, itching of the scalp, eczema, mastitis and torsion The diseases such as the itch pain that wound, contusion, pain in the back, courbature, arthralgia, neuralgia, headache and bite by mosquitos cause.

This ointment not only has the effect of anti-inflammation, also has to local skin irritation, can promote local blood Circulation, external application or local are embrocated and can be produced the IRs such as cutaneous vasodilation, the colour of skin be rubescent, and reflectivity ground affects corresponding portion The skin of position, muscle, nerve and joint, play detumescence, anti-inflammatory and analgesic activity, also have antipruritic effect.For spraining, dampening, waist Bitterly, courbature, arthralgia, neuralgia, headache and bite by mosquitos.

It is used for when treating tinea pedis, once efficient 95%, be almost recovered for 4 to 5 times, cure rate 90%, consolidate curative effect and arrived with 3 again 6 basic eliminations, will not recur in a short time.

（Four）It is embodied as

The following is an a kind of specific embodiment of the antipruritic traditional Chinese herb medicine of anti-inflammation of the present invention, main active principle is toad Grass, based on the quality of each raw material components, number dispensing is as follows：80 parts of toad grass, 5 parts of cloves, 3 parts of honeysuckle, 3 parts of the root of large-flowered skullcap, fourth 3 parts of perfume, 3 parts of the coptis, 4 parts of the capsule of weeping forsythia, 2 parts of camphorated oil, 4 parts of golden cypress, 2 parts of peppermint oil, 4 parts of borneol, 2 parts of volatile oil extracted from eucalyptus' leaves or twigs, 6 parts of Chinese prickly ash, Chinese mugwort 4 parts of leaf.

Preparation method is as follows：

Get the raw materials ready：With above-mentioned other non-oily drug component honeysuckles 3 after the section that toad 80 parts of herb of grass is cut into 1 centimeter length Part, 3 parts of the root of large-flowered skullcap, 5 parts of cloves, 3 parts of the coptis, 4 parts of the capsule of weeping forsythia, 4 parts of golden cypress, 4 parts of borneol, 6 parts of Chinese prickly ash, 4 parts of prepared slices of Chinese crude drugs of tarragon mix Close standby；

Soak

First above-mentioned non-oily drug component is put in the suitable clean marmite of capacity, plus appropriate water infiltration spice, make it fill Point absorb and to expand, add water after a while to exceed powder 5cm, soak 24h.

Decoction filtering

Above-mentioned spice after soaking is got angry decoction.First boiled with big fire, then with boiling with soft fire 1h about, switching to low baking temperature to boil is Degree, about 3h, go out slubbing concoction with filtered through gauze, then plus the original dregs of a decoction of clear water infiltration after get angry decoctions, decoction is the same, the net medicine of filter After juice, the dregs of a decoction are abandoned.Decoct the mixing of gained concoction by front twice, after standing, reprecipitation filters, and removes the dregs of a decoction.

It is concentrated by evaporation into cream

Filter in the net concoction pot of falling people, concentrated, can first be decocted with big fire, accelerate moisture evaporation, allow concoction slowly to become Thick, then use small fire instead and heat further and be stirred continuously, so that concoction is concentrated further, do not scatter on paper to being stirred to concoction and dropping in Till coming, stop decocting, here it is through the clear cream concentrating.

Lapping-in

The above-mentioned clear cream through concentrating is added the oiliness groups such as 2 parts of the camphorated oil got ready in advance, 2 parts of peppermint oil, 2 parts of volatile oil extracted from eucalyptus' leaves or twigs Divide and become fine and smooth pasty state with 1 part of vaseline, the ointment bases mixed grinding such as 1 part of lanolin, 1 part of stearic acid, then with every 5 grams for one Part, mounted box seal, perform date, weight, title etc. mark, be positioned over cool place be dried lucifuge ventilation storage stand-by.

Using method：It is para-infectious by the easily pathogenic bacteria such as fungi that the ointment that this drug regimen is made directly is applied to human body Disease sites and by bite by mosquitos, for treating tinea pedis, carbuncle swells, hemorrhoid, anus swell and ache, itching of the scalp, eczema, mastitis And sprain, dampen, the disease such as itch pain that pain in the back, courbature, arthralgia, headache and bite by mosquitos cause.

The following is ointment of the present invention easily to cause a disease the disease that fungus attack and bite by mosquitos cause for treating fungi etc. One group of concrete clinical testing data：

Test site：Select the big city Jinan City of the non-coastal non-wet thermal climate of central China

Test season：Summer 7 arrives August part, compares how sultry wet weather, the season that skin disease is easily sent out, mosquito is more.

Test crowd：Tinea pedis 50, perianal eczema Disease 20, itching of the scalp 30, arthralgia 30, vulva scabies Itch 20, bite by mosquitos 20；Age 22 to 60, average age 40 years old, the habits and customs of testing crew and working environment will It is not very severe for asking relatively stable again, and working environment will not have too big change, the comparability of test data during testing Relatively higher.

Test method：Before smearing above-mentioned ointment every time, first with warm water, the disease sites of patient are cleaned up, remove Secretion and dirt, are smeared uniformly with above-mentioned ointment.Sooner or later respectively once, 5 days is a course for the treatment of, under withdrawal observation is carried out for 3 days again One course for the treatment of, tests 2 courses for the treatment of altogether, and each course for the treatment of carries out effective evaluation after terminating.Prohibit the use of during treatment and take other Medicine and treatment method, in order to avoid affect this test effect.

Efficacy assessment standard：

1st, invalid：Compare with before treatment, symptom is not improved, or have and increase trend；

2nd, effective：Compare with before treatment, symptom substantially mitigates；

3rd, fully recover：Compare with before treatment, symptom is wholly absent.

Conclusion (of pressure testing)：Drug test process does not find the bad reactions such as allergic symptom, and test effect shows that the present invention uses Safety, total effective rate more than 93%, and also a course for the treatment of basically reaches therapeutic effect.It is bacterium infection class and non-bacterial causes Inflammation class disease active drug, there is clinical value and promotional value.

Because the morbidity of gynaecological imflammation class disease is mainly what bacterium infection caused, itself physique of patient, bad life Custom particularly sexual life custom and the factor such as used underwear, socks all may cause palindromia, cure and are not equal to root Remove.So being likely to after curing recur, want to eradicate the habits and customs that gynaecological imflammation class disease must form well cleaning, especially It is sexual life custom, give up unclean sexual life and the habit of multiple sex partner.

Because the morbidity of tinea pedis is mainly what fungal infection caused, itself physique of patient, bad life habits and use The factor such as the footgear crossed and shoe chest residual fungi all may cause tinea pedis to recur, so tinea pedis is likely to after curing recur, eradicates The hope of tinea pedis is typically little, cures and is not equal to elimination.

In addition, Lee the present inventor is wise and able suffers from tinea pedis and perianal eczema for many years, all mild episode 3 to 5 times of annual summer, Attack degree simply somewhat has the sensation scratched where it itches, as long as now timely use after ointment of the present invention smears three to five times just may be used every time Recovery from illness, at ordinary times only it is noted that the sanitation and hygiene of holding foot and anus and drying, typically will not recur, even if recurrence is also easy to Cure, demonstrate the definite curative effect of ointment of the present invention in person.

Claims (2)

1. antipruritic traditional Chinese herb medicine of a kind of anti-inflammation and preparation method thereof, is characterized in that the quality meter number proportioning of each raw material components For 70～80 parts of toad grass, 1～3 part of honeysuckle, 1～5 part of cloves, 1～3 part of the root of large-flowered skullcap, 1～5 part of the coptis, 1～6 part of the capsule of weeping forsythia, 1～7 part of camphorated oil, 1～5 part of golden cypress, 1～6 part of peppermint oil, 1～4 part of borneol, 1～3 part of volatile oil extracted from eucalyptus' leaves or twigs, 1～6 part of Chinese prickly ash, tarragon 1～ 4 parts.

2. a kind of anti-inflammation traditional Chinese herb medicine according to claim 1, is characterized in that its preparation method is by above-mentioned raw materials Middle non-oily drug component is through getting the raw materials ready, soaking, decoction filtering, be concentrated by evaporation into after cream the medium oil component and 1 with above-mentioned raw materials Part vaseline, the ointment bases mixed grinding such as 1 part of lanolin, 1 part of stearic acid become fine and smooth pasty state, are then portion with every 5 grams, fill Box seal, perform date, weight, title etc. mark, be positioned over cool place be dried lucifuge ventilation storage stand-by.