CN106350488B - 用于***的pd-1封闭cik的制备方法 - Google Patents
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- CN106350488B CN106350488B CN201610833367.0A CN201610833367A CN106350488B CN 106350488 B CN106350488 B CN 106350488B CN 201610833367 A CN201610833367 A CN 201610833367A CN 106350488 B CN106350488 B CN 106350488B
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
- C12N5/06—Animal cells or tissues; Human cells or tissues
- C12N5/0602—Vertebrate cells
- C12N5/0634—Cells from the blood or the immune system
- C12N5/0646—Natural killers cells [NK], NKT cells
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K35/14—Blood; Artificial blood
- A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/23—Interleukins [IL]
- C12N2501/2302—Interleukin-2 (IL-2)
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N2501/00—Active agents used in cell culture processes, e.g. differentation
- C12N2501/20—Cytokines; Chemokines
- C12N2501/24—Interferons [IFN]
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CN201610833367.0A CN106350488B (zh) | 2016-09-19 | 2016-09-19 | 用于***的pd-1封闭cik的制备方法 |
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CN201610833367.0A CN106350488B (zh) | 2016-09-19 | 2016-09-19 | 用于***的pd-1封闭cik的制备方法 |
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CN106350488A CN106350488A (zh) | 2017-01-25 |
CN106350488B true CN106350488B (zh) | 2019-09-27 |
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CN201610833367.0A Active CN106350488B (zh) | 2016-09-19 | 2016-09-19 | 用于***的pd-1封闭cik的制备方法 |
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Families Citing this family (4)
Publication number | Priority date | Publication date | Assignee | Title |
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CN108048397A (zh) * | 2017-12-15 | 2018-05-18 | 海南博鳌银丰康养国际医院有限公司 | 一种利用靶向pd-1抗体沉默免疫细胞负调控受体的方法 |
CN109913413B (zh) * | 2019-03-05 | 2020-10-30 | 广州筑康生物技术有限公司 | 一种加载pd-1抗体的t细胞体外培养方法、其细胞制剂及其应用 |
CN110747167B (zh) * | 2019-10-31 | 2021-11-02 | 秦森邦 | 一种半合子bak细胞的制备方法及其应用 |
CN110656084B (zh) * | 2019-10-31 | 2021-10-01 | 秦森邦 | Bak细胞及其制备试剂盒和制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105713878A (zh) * | 2015-12-21 | 2016-06-29 | 杭州特马赛生物技术有限公司 | 一种体外扩增cd8+t细胞的方法 |
CN105861433A (zh) * | 2016-04-27 | 2016-08-17 | 天津普瑞赛尔生物科技有限公司 | 制备具有高效肿瘤杀伤性cik细胞制剂的方法及制得的cik细胞制剂 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
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JOP20200094A1 (ar) * | 2014-01-24 | 2017-06-16 | Dana Farber Cancer Inst Inc | جزيئات جسم مضاد لـ pd-1 واستخداماتها |
WO2016054555A2 (en) * | 2014-10-03 | 2016-04-07 | Novartis Ag | Combination therapies |
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- 2016-09-19 CN CN201610833367.0A patent/CN106350488B/zh active Active
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
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CN105713878A (zh) * | 2015-12-21 | 2016-06-29 | 杭州特马赛生物技术有限公司 | 一种体外扩增cd8+t细胞的方法 |
CN105861433A (zh) * | 2016-04-27 | 2016-08-17 | 天津普瑞赛尔生物科技有限公司 | 制备具有高效肿瘤杀伤性cik细胞制剂的方法及制得的cik细胞制剂 |
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