CN106317050B - 一种苯基噻唑衍生物及其制备方法与应用 - Google Patents
一种苯基噻唑衍生物及其制备方法与应用 Download PDFInfo
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- CN106317050B CN106317050B CN201610711245.4A CN201610711245A CN106317050B CN 106317050 B CN106317050 B CN 106317050B CN 201610711245 A CN201610711245 A CN 201610711245A CN 106317050 B CN106317050 B CN 106317050B
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- trpc6
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
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- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
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CN201610711245.4A CN106317050B (zh) | 2016-08-24 | 2016-08-24 | 一种苯基噻唑衍生物及其制备方法与应用 |
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CN201610711245.4A CN106317050B (zh) | 2016-08-24 | 2016-08-24 | 一种苯基噻唑衍生物及其制备方法与应用 |
Publications (2)
Publication Number | Publication Date |
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CN106317050A CN106317050A (zh) | 2017-01-11 |
CN106317050B true CN106317050B (zh) | 2018-11-23 |
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CN201610711245.4A Active CN106317050B (zh) | 2016-08-24 | 2016-08-24 | 一种苯基噻唑衍生物及其制备方法与应用 |
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Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
PT3786160T (pt) | 2017-10-27 | 2022-08-19 | Boehringer Ingelheim Int | Derivados de piridina e suas utilizações terapêuticas como inibidores de trpc6 |
CN109666006B (zh) * | 2018-12-07 | 2022-09-02 | 烟台大学 | 芳基衍生联噻唑类化合物及其制备方法和应用 |
AR121846A1 (es) | 2020-04-16 | 2022-07-13 | Teijin Pharma Ltd | Derivado de arilo o heteroarilo |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1948502A (zh) * | 2005-10-14 | 2007-04-18 | 中国科学院上海生命科学研究院 | Trpc在抗肿瘤药物筛选中的应用及其抑制剂的药物用途 |
CN101048158A (zh) * | 2004-08-13 | 2007-10-03 | 健泰科生物技术公司 | 利用atp的酶的噻唑-类抑制剂 |
CN104987345A (zh) * | 2009-09-28 | 2015-10-21 | 霍夫曼-拉罗奇有限公司 | 苯并氧杂*pi3k抑制剂化合物和使用方法 |
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2016
- 2016-08-24 CN CN201610711245.4A patent/CN106317050B/zh active Active
Patent Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN101048158A (zh) * | 2004-08-13 | 2007-10-03 | 健泰科生物技术公司 | 利用atp的酶的噻唑-类抑制剂 |
CN1948502A (zh) * | 2005-10-14 | 2007-04-18 | 中国科学院上海生命科学研究院 | Trpc在抗肿瘤药物筛选中的应用及其抑制剂的药物用途 |
CN104987345A (zh) * | 2009-09-28 | 2015-10-21 | 霍夫曼-拉罗奇有限公司 | 苯并氧杂*pi3k抑制剂化合物和使用方法 |
Non-Patent Citations (2)
Title |
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460999-40-0;CA;《STN-Registry》;20021014;第1页 * |
483983-49-9;CA;《STN-Registry》;20030131;第1页 * |
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CN106317050A (zh) | 2017-01-11 |
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Application publication date: 20170111 Assignee: Shandong Luye Pharmaceutical Co.,Ltd. Assignor: Yantai University Contract record no.: X2020990000071 Denomination of invention: Pheny-ithiaxal derivative and preparing method and application thereof Granted publication date: 20181123 License type: Common License Record date: 20200210 |
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Denomination of invention: A phenylthiazole derivative and its preparation method and Application Effective date of registration: 20211214 Granted publication date: 20181123 Pledgee: Yantai financing guarantee Group Co.,Ltd. Pledgor: Yantai University Registration number: Y2021980014850 |
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