CN106309593A - Preparation method for traditional Chinese medicine formula for relieving dry psoriasis - Google Patents
Preparation method for traditional Chinese medicine formula for relieving dry psoriasis Download PDFInfo
- Publication number
- CN106309593A CN106309593A CN201610995442.3A CN201610995442A CN106309593A CN 106309593 A CN106309593 A CN 106309593A CN 201610995442 A CN201610995442 A CN 201610995442A CN 106309593 A CN106309593 A CN 106309593A
- Authority
- CN
- China
- Prior art keywords
- chinese medicine
- preparation
- medicine
- blood
- alleviating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Withdrawn
Links
- 239000003814 drug Substances 0.000 title claims abstract description 75
- 238000002360 preparation method Methods 0.000 title claims abstract description 15
- 201000004681 Psoriasis Diseases 0.000 title abstract description 13
- 229940079593 drug Drugs 0.000 claims abstract description 17
- XLYOFNOQVPJJNP-UHFFFAOYSA-N water Substances O XLYOFNOQVPJJNP-UHFFFAOYSA-N 0.000 claims abstract description 17
- 238000000034 method Methods 0.000 claims abstract description 7
- 239000002994 raw material Substances 0.000 claims abstract description 5
- 238000002791 soaking Methods 0.000 claims abstract description 3
- 230000001185 psoriatic effect Effects 0.000 claims description 17
- 239000007788 liquid Substances 0.000 claims description 8
- 241000903946 Clematidis Species 0.000 claims description 6
- VYQNWZOUAUKGHI-UHFFFAOYSA-N monobenzone Chemical compound C1=CC(O)=CC=C1OCC1=CC=CC=C1 VYQNWZOUAUKGHI-UHFFFAOYSA-N 0.000 claims description 6
- 238000007654 immersion Methods 0.000 claims description 4
- 210000003298 dental enamel Anatomy 0.000 claims description 3
- 238000003756 stirring Methods 0.000 claims description 3
- 238000009835 boiling Methods 0.000 claims description 2
- 238000010438 heat treatment Methods 0.000 claims description 2
- 238000002386 leaching Methods 0.000 claims description 2
- 230000000694 effects Effects 0.000 abstract description 10
- 206010067482 No adverse event Diseases 0.000 abstract 1
- 238000004140 cleaning Methods 0.000 abstract 1
- 238000001914 filtration Methods 0.000 abstract 1
- 231100000252 nontoxic Toxicity 0.000 abstract 1
- 206010015150 Erythema Diseases 0.000 description 12
- 231100000321 erythema Toxicity 0.000 description 11
- 208000003251 Pruritus Diseases 0.000 description 8
- 239000000203 mixture Substances 0.000 description 8
- 210000004185 liver Anatomy 0.000 description 7
- 210000002105 tongue Anatomy 0.000 description 7
- 208000002474 Tinea Diseases 0.000 description 6
- 210000004369 blood Anatomy 0.000 description 6
- 239000008280 blood Substances 0.000 description 6
- 210000003734 kidney Anatomy 0.000 description 6
- 241000130764 Tinea Species 0.000 description 5
- 201000010099 disease Diseases 0.000 description 5
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 5
- 230000007958 sleep Effects 0.000 description 5
- 210000000952 spleen Anatomy 0.000 description 4
- 230000035900 sweating Effects 0.000 description 4
- 206010011224 Cough Diseases 0.000 description 3
- 230000001684 chronic effect Effects 0.000 description 3
- 235000009508 confectionery Nutrition 0.000 description 3
- 210000002216 heart Anatomy 0.000 description 3
- 231100000614 poison Toxicity 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 238000012360 testing method Methods 0.000 description 3
- 206010007247 Carbuncle Diseases 0.000 description 2
- 206010010774 Constipation Diseases 0.000 description 2
- 206010017533 Fungal infection Diseases 0.000 description 2
- 208000032843 Hemorrhage Diseases 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 241000699670 Mus sp. Species 0.000 description 2
- 208000031888 Mycoses Diseases 0.000 description 2
- FAPWRFPIFSIZLT-UHFFFAOYSA-M Sodium chloride Chemical compound [Na+].[Cl-] FAPWRFPIFSIZLT-UHFFFAOYSA-M 0.000 description 2
- 230000005856 abnormality Effects 0.000 description 2
- 239000003429 antifungal agent Substances 0.000 description 2
- 210000000988 bone and bone Anatomy 0.000 description 2
- 230000001914 calming effect Effects 0.000 description 2
- 230000001276 controlling effect Effects 0.000 description 2
- 230000007812 deficiency Effects 0.000 description 2
- 230000001934 delay Effects 0.000 description 2
- 208000001848 dysentery Diseases 0.000 description 2
- 208000001780 epistaxis Diseases 0.000 description 2
- 210000003414 extremity Anatomy 0.000 description 2
- 238000003304 gavage Methods 0.000 description 2
- 208000013403 hyperactivity Diseases 0.000 description 2
- 239000008141 laxative Substances 0.000 description 2
- 210000004072 lung Anatomy 0.000 description 2
- 239000002932 luster Substances 0.000 description 2
- 230000003340 mental effect Effects 0.000 description 2
- 239000002574 poison Substances 0.000 description 2
- 230000001737 promoting effect Effects 0.000 description 2
- 238000011084 recovery Methods 0.000 description 2
- 206010040882 skin lesion Diseases 0.000 description 2
- 231100000444 skin lesion Toxicity 0.000 description 2
- 239000011780 sodium chloride Substances 0.000 description 2
- 230000002269 spontaneous effect Effects 0.000 description 2
- 210000002784 stomach Anatomy 0.000 description 2
- 238000002560 therapeutic procedure Methods 0.000 description 2
- 210000001835 viscera Anatomy 0.000 description 2
- MCSXGCZMEPXKIW-UHFFFAOYSA-N 3-hydroxy-4-[(4-methyl-2-nitrophenyl)diazenyl]-N-(3-nitrophenyl)naphthalene-2-carboxamide Chemical compound Cc1ccc(N=Nc2c(O)c(cc3ccccc23)C(=O)Nc2cccc(c2)[N+]([O-])=O)c(c1)[N+]([O-])=O MCSXGCZMEPXKIW-UHFFFAOYSA-N 0.000 description 1
- 208000008035 Back Pain Diseases 0.000 description 1
- 241000894006 Bacteria Species 0.000 description 1
- 206010005913 Body tinea Diseases 0.000 description 1
- 206010053567 Coagulopathies Diseases 0.000 description 1
- 206010051625 Conjunctival hyperaemia Diseases 0.000 description 1
- 206010010904 Convulsion Diseases 0.000 description 1
- 208000001840 Dandruff Diseases 0.000 description 1
- 206010012289 Dementia Diseases 0.000 description 1
- 206010048768 Dermatosis Diseases 0.000 description 1
- 206010012735 Diarrhoea Diseases 0.000 description 1
- 208000000059 Dyspnea Diseases 0.000 description 1
- 206010013975 Dyspnoeas Diseases 0.000 description 1
- 208000036119 Frailty Diseases 0.000 description 1
- 241000233866 Fungi Species 0.000 description 1
- PEDCQBHIVMGVHV-UHFFFAOYSA-N Glycerine Chemical compound OCC(O)CO PEDCQBHIVMGVHV-UHFFFAOYSA-N 0.000 description 1
- 206010019233 Headaches Diseases 0.000 description 1
- 206010019705 Hepatic pain Diseases 0.000 description 1
- 206010062717 Increased upper airway secretion Diseases 0.000 description 1
- 206010061218 Inflammation Diseases 0.000 description 1
- 208000008930 Low Back Pain Diseases 0.000 description 1
- 206010027514 Metrorrhagia Diseases 0.000 description 1
- 241000699666 Mus <mouse, genus> Species 0.000 description 1
- 241000475481 Nebula Species 0.000 description 1
- 206010029412 Nightmare Diseases 0.000 description 1
- 206010059013 Nocturnal emission Diseases 0.000 description 1
- 241000237502 Ostreidae Species 0.000 description 1
- 208000002193 Pain Diseases 0.000 description 1
- 206010033557 Palpitations Diseases 0.000 description 1
- 206010037660 Pyrexia Diseases 0.000 description 1
- 206010037888 Rash pustular Diseases 0.000 description 1
- 206010040943 Skin Ulcer Diseases 0.000 description 1
- 208000013738 Sleep Initiation and Maintenance disease Diseases 0.000 description 1
- 206010043866 Tinea capitis Diseases 0.000 description 1
- 201000010618 Tinea cruris Diseases 0.000 description 1
- 206010067197 Tinea manuum Diseases 0.000 description 1
- 208000025865 Ulcer Diseases 0.000 description 1
- 208000031971 Yin Deficiency Diseases 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 239000002253 acid Substances 0.000 description 1
- 206010000496 acne Diseases 0.000 description 1
- 231100000215 acute (single dose) toxicity testing Toxicity 0.000 description 1
- 230000001154 acute effect Effects 0.000 description 1
- 238000011047 acute toxicity test Methods 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 230000000202 analgesic effect Effects 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 206010003549 asthenia Diseases 0.000 description 1
- 208000034158 bleeding Diseases 0.000 description 1
- 230000000740 bleeding effect Effects 0.000 description 1
- 208000002352 blister Diseases 0.000 description 1
- 230000037396 body weight Effects 0.000 description 1
- 210000000481 breast Anatomy 0.000 description 1
- 210000000038 chest Anatomy 0.000 description 1
- 229940126678 chinese medicines Drugs 0.000 description 1
- 208000013116 chronic cough Diseases 0.000 description 1
- 230000035602 clotting Effects 0.000 description 1
- 230000036461 convulsion Effects 0.000 description 1
- 238000001816 cooling Methods 0.000 description 1
- 230000006378 damage Effects 0.000 description 1
- 230000000994 depressogenic effect Effects 0.000 description 1
- 230000009429 distress Effects 0.000 description 1
- 206010013781 dry mouth Diseases 0.000 description 1
- 238000005516 engineering process Methods 0.000 description 1
- 230000004438 eyesight Effects 0.000 description 1
- 210000004905 finger nail Anatomy 0.000 description 1
- 235000013305 food Nutrition 0.000 description 1
- 210000002683 foot Anatomy 0.000 description 1
- 230000002538 fungal effect Effects 0.000 description 1
- 210000000232 gallbladder Anatomy 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 238000005469 granulation Methods 0.000 description 1
- 230000003179 granulation Effects 0.000 description 1
- 230000002984 haematinic effect Effects 0.000 description 1
- 231100000869 headache Toxicity 0.000 description 1
- 208000035861 hematochezia Diseases 0.000 description 1
- 208000014617 hemorrhoid Diseases 0.000 description 1
- 230000001771 impaired effect Effects 0.000 description 1
- 230000002757 inflammatory effect Effects 0.000 description 1
- 230000004054 inflammatory process Effects 0.000 description 1
- 238000001802 infusion Methods 0.000 description 1
- 206010022437 insomnia Diseases 0.000 description 1
- 210000000936 intestine Anatomy 0.000 description 1
- 230000007803 itching Effects 0.000 description 1
- 210000002429 large intestine Anatomy 0.000 description 1
- 230000002475 laxative effect Effects 0.000 description 1
- RYZCLUQMCYZBJQ-UHFFFAOYSA-H lead(2+);dicarbonate;dihydroxide Chemical compound [OH-].[OH-].[Pb+2].[Pb+2].[Pb+2].[O-]C([O-])=O.[O-]C([O-])=O RYZCLUQMCYZBJQ-UHFFFAOYSA-H 0.000 description 1
- 210000000265 leukocyte Anatomy 0.000 description 1
- 231100001252 long-term toxicity Toxicity 0.000 description 1
- 201000007227 lymph node tuberculosis Diseases 0.000 description 1
- 201000004792 malaria Diseases 0.000 description 1
- 239000000463 material Substances 0.000 description 1
- 210000004914 menses Anatomy 0.000 description 1
- 230000005906 menstruation Effects 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 210000000056 organ Anatomy 0.000 description 1
- 235000020636 oyster Nutrition 0.000 description 1
- 230000008506 pathogenesis Effects 0.000 description 1
- 230000001717 pathogenic effect Effects 0.000 description 1
- 230000002093 peripheral effect Effects 0.000 description 1
- 208000026435 phlegm Diseases 0.000 description 1
- 230000019612 pigmentation Effects 0.000 description 1
- 208000014267 psoriasis 8 Diseases 0.000 description 1
- 230000001543 purgative effect Effects 0.000 description 1
- 208000029561 pustule Diseases 0.000 description 1
- 230000001105 regulatory effect Effects 0.000 description 1
- 210000004761 scalp Anatomy 0.000 description 1
- 210000000582 semen Anatomy 0.000 description 1
- 210000002027 skeletal muscle Anatomy 0.000 description 1
- 208000017520 skin disease Diseases 0.000 description 1
- 231100000019 skin ulcer Toxicity 0.000 description 1
- 201000009032 substance abuse Diseases 0.000 description 1
- 201000003875 tinea corporis Diseases 0.000 description 1
- 201000004647 tinea pedis Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 239000003440 toxic substance Substances 0.000 description 1
- 231100000820 toxicity test Toxicity 0.000 description 1
- 238000009602 toxicology test Methods 0.000 description 1
- 239000003053 toxin Substances 0.000 description 1
- 231100000765 toxin Toxicity 0.000 description 1
- 231100000397 ulcer Toxicity 0.000 description 1
- 210000003462 vein Anatomy 0.000 description 1
- 230000002618 waking effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/02—Medicinal preparations containing materials or reaction products thereof with undetermined constitution from inanimate materials
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/58—Reptiles
- A61K35/586—Turtles; Tortoises, e.g. terrapins
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/56—Materials from animals other than mammals
- A61K35/618—Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/48—Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
- A61K36/484—Glycyrrhiza (licorice)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/65—Paeoniaceae (Peony family), e.g. Chinese peony
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/70—Polygonaceae (Buckwheat family), e.g. spineflower or dock
- A61K36/704—Polygonum, e.g. knotweed
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/71—Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
- A61K36/716—Clematis (leather flower)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/33—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
- A61K2236/331—Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation or decoction
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2236/00—Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
- A61K2236/30—Extraction of the material
- A61K2236/39—Complex extraction schemes, e.g. fractionation or repeated extraction steps
Landscapes
- Health & Medical Sciences (AREA)
- Natural Medicines & Medicinal Plants (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Alternative & Traditional Medicine (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Medical Informatics (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Marine Sciences & Fisheries (AREA)
- Zoology (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
Abstract
The invention discloses a preparation method for a traditional Chinese medicine formula for relieving dry psoriasis. The method comprises the following steps: (1) weighting drugs by weight part; (2) cleaning and soaking the weighted drugs; (3) putting the soaked drugs into a decocting pot and preparing for decoction; (4) decocting with strong fire and then decocting with slow fire; (5) after decocting, adding water and decocting for the second time; (6) filtering the drugs. According to the preparation method for the traditional Chinese medicine formula provided by the invention, the steps in the operation process are clear, scientific and precise; a conclusion made on the basis of years of experience proves that the prepared medicine has an obvious effect in treating dry psoriasis; the selected medicine raw materials have no toxic effect to each other; the medicine is suitable for both mild and severe dry psoriasis patients; the application scope is wide; the method is scientific and clear; the steps are simple; the operation is convenient.
Description
Technical field
The present invention relates to technical field of Chinese medicines, specifically refer to a kind of system for alleviating the psoriatic Chinese medicine formula of blood-dryness type
Preparation Method.
Background technology
Psoriasis is commonly called as psoriasis, is that a kind of chronic inflammatory skin is sick, and the course of disease is longer, has easy tendency of recurrence, some diseases
Example almost cannot be cured all one's life.This disease is fallen ill based on person between twenty and fifty, affects bigger on the healthy of patient and mental status.Clinical table
Now with erythema, squama is main, and whole body all can be fallen ill, and with scalp, it is relatively conventional that extremity stretch side, increases the weight of the most in the winter time.
Psoriasis psoriasis one word is summarized this name of disease and is claimed to be the most unscientific, because psoriasis is not in fact
Tinea.So-called " tinea ", medically refers to some dermatosiss caused due to fungal infection, such as tinea capitis, tinea cruris, tinea corporis, tinea manus and pedis,
Fingernail tinea etc..The scurf of these tinea local is put and the most often can find that fungal mycelia or fungus make spore, use anti-true
Bacterium medicine carries out treating and often can obtain good curative effect.It is characterized in that the pimple occurring differing in size, erythema, surface is covered with silver
White squama.Psoriasis is not caused by fungal infection, is medically referred to as psoriasis.Its pathogenic factor is the most multiple
Miscellaneous, it is the most invalid to carry out treating with antifungal drug.Therefore, some patient can strain the meaning of the word, oneself take antifungal drug or
Person abuses and is coated with outside tinea medicine, instead results in and wastes money, increases the weight of the state of an illness.And owing to psoriasis is owing to body interior occurs different
Often, just cause external skin impaired and the damage of people's psychiatric aspect, so using Chinese medicine can psoriatic treatment be had very
Good curative effect.
Summary of the invention
It is an object of the invention to provide one can significantly disappear erythema, squama, alleviate skin pruritus sense, science is clear and definite,
Step is simplified, the preparation method of the Chinese medicine formula of convenient operation.
The present invention is achieved through the following technical solutions: a kind of preparation side for alleviating the psoriatic Chinese medicine formula of blood-dryness type
Method, by weight, including: Os Draconis 4-17 part, Concha Ostreae 3-22 part, Carapax et Plastrum Testudinis 5-15 part, Radix Polygoni Multiflori 4-15 part, Radix Clematidis 6-18
Part, Radix Paeoniae Alba 5-18 part, Fructus Tribuli 4-16 part, Radix Glycyrrhizae 10-30 part.
The crude drug pharmacology of a kind of preparation method for alleviating the psoriatic Chinese medicine formula of blood-dryness type of the present invention:
Os Draconis: sweet in the mouth, puckery, property is put down.Enter the heart, liver, kidney, large intestine channel.Having tranquillization with heavy prescription, arresting sweating controlling nocturnal emission with astringent drugs, stop blooding astringing intestine to stop diarrhea, and granulation promoting is held back
The effect of skin ulcer.Controlling infantile convulsion demented, palpitation with a distress feeling is forgetful, insomnia and dreamful sleep, spontaneous sweating, stranguria with turbid discharge of passing out semen, and tells nosebleed and has blood in stool, and bleeding not during menses rushes down
Dysentery proctoptosis, ulcer does not closes up.
Concha Ostreae: cold nature, salty in the mouth.Return Liver Channel, gallbladder meridian, kidney channel.Tranquillization with heavy prescription, YANG hyperactivity suppressing nourishing YIN, hard masses softening and resolving, Concha Ostreae (calcined) is received
Hold back astringent or styptic treatment for spontaneous sweating.Belong to the suppressing liver-YANG medicine of medicine for calming liver and calming endopathic wind subordinate classification.
Carapax et Plastrum Testudinis: salty in the mouth, property is put down.Enter the heart, spleen, liver three warp.YIN nourishing, YANG hyperactivity suppressing, the kidney invigorating, strong bone.Control deficiency of kidney yin, hectic fever due to YIN-deficiency labor
Heat, spits blood, epistaxis, chronic cough, and seminal emission, metrorrhagia, leukorrhagia, lumbago, the atrophic debility of bones, stirring of wind due to deficiency of YIN, chronic dysentery, chronic malaria, hemorrhoid, children's's fontanel is not
Close.
Radix Polygoni Multiflori: warm in nature is bitter in the mouth, sweet, puckery.Return Liver Channel, kidney channel, heart channel.Removing toxic substances, eliminating carbuncle, loosening bowel to relieve constipation.Belong under purgatives medicine
The laxative drug of classification.
Radix Clematidis: warm in nature is acrid in the mouth, salty.Return bladder warp.Expelling wind and removing dampness, removing obstruction in the collateral to relieve pain.Belong to dispelling of damp disease subordinate classification of dispeling the wind
Rheumatism cold expelling medicine.The Radix Paeoniae Alba: cold nature, bitter in the mouth, acid.Return Liver Channel, spleen channel.Suppressing the hyperactive liver pain relieving, nourishing blood for regulating menstruation, astringing YIN to stop sweating.Belong to qi-restoratives
The hematonic of medicine subordinate classification.
Fructus Tribuli: bitter in the mouth, warm in nature.Enter lung, liver, kidney three warp.Dissipate wind, improving eyesight, the therapeutic method to keep the adverse QI flowing downwards, promoting the circulation of blood.Control headache, itching over the body, conjunctival congestion
Swollen nebula, fullness in the chest, cough with dyspnea, lump in the abdomen, breast is difficult, carbuncle, scrofula.
Radix Glycyrrhizae: property is put down, sweet in the mouth.GUIXIN warp, stomach warp, spleen channel, lung meridian.Invigorating the spleen and replenishing QI, eliminating phlegm and stopping cough, emergency analgesic therapy, mediation
The property of medicine.Belong to the Qi-tonifying drug of classification under qi-restoratives medicine.
Further, in described step (3), decocting container is marmite, enamel ware, avoids and uses ironware.
Further, twice decoction in described step (4) and step (5) includes the soak by water 2 adding 10 times amount for the first time
Hour, second time adds the soak by water 1 hour of 8 times amount.
Further, in described step (4), slow fire fried time was no less than 30 minutes.
Further, in described step (6), filtered drug uses filtered through gauze net to filter.
The preparation method of the Chinese medicine composition of present invention step in operation clearly and also scientific and precise, be through too much
The conclusion that the experience in year is made, the medicine produced has obvious effect to psoriatic treatment, and the medicine material chosen is mutual
Between there is no toxic and side effects, slight and severe psoriatic can use, applied widely, and science clearly, simplify by step,
Convenient operation.
Detailed description of the invention
Below in conjunction with embodiment, the present invention is described in further detail, but embodiments of the present invention is not limited to this,
Without departing from the idea case in the present invention described above, according to ordinary skill knowledge and customary means, make various replacing
Change and change, all should be included within the scope of the invention.
Embodiment 1:
A kind of preparation method for alleviating the psoriatic Chinese medicine formula of blood-dryness type described in the present embodiment, comprises the following steps:
(1) represent with weight portion, weigh Os Draconis 4-17 part, Concha Ostreae 3-22 part, Carapax et Plastrum Testudinis 5-15 part, Radix Polygoni Multiflori 4-15 part, Radix Clematidis
6-18 part, Radix Paeoniae Alba 5-18 part, Fructus Tribuli 4-16 part, Radix Glycyrrhizae 10-30 part；
(2) by above-mentioned whole raw material of Chinese medicine medicines, to soak 30 minutes with clear water or pure water in advance, water consumption for immersion is 0.9 ~
1.1L；
(3) raw material of Chinese medicine medicine and the liquid medicine of immersion thereof after soaking join in decocting container, add a cover and jointly decoct；
(4) first make decocting container herb liquid seethe with excitement with high heat, re-use slow fire and boil, need to stir when boiling medicine 2 ~ 3 times；
(5) after having decocted, add proper amount of clear water or pure water did not had medicine, carry out second time and decoct, decoct duration and degree of heating method ibid；
(6) leaching medicinal liquid, obtained medicinal liquid is endo-medicine.
Wherein, in described step (3), decocting container is marmite, enamel ware, avoids by ironware, described step (4) and step
(5) twice decoction in includes adding for the first time the soak by water 2 hours of 10 times amount, and second time adds the soak by water 1 hour of 8 times amount, institute
Stating in step (4), slow fire fried time, in described step (6), filtered drug used filtered through gauze net to enter no less than 30 minutes
Row filters.
Embodiment 2:
It is used for alleviating the psoriatic Chinese medicine composition of blood-dryness type described in the present embodiment, by weight, including: Os Draconis 10 parts, male
Oyster 18 parts, Carapax et Plastrum Testudinis 11 parts, Radix Polygoni Multiflori 7 parts, Radix Clematidis 11 parts, the Radix Paeoniae Alba 15 parts, Fructus Tribuli 14 parts, 20 parts of Radix Glycyrrhizae.
Embodiment 3:
The present embodiment is on the basis of above-described embodiment, further, also includes Radix Rehmanniae Preparata 3-23 part, Periostracum Cicadae 5-25 part, Rhizoma Chuanxiong 4-
15 parts.The most originally it is used for alleviating the psoriatic Chinese medicine composition of blood-dryness type, by weight, including: Os Draconis 10 parts, Concha Ostreae 18 parts,
Carapax et Plastrum Testudinis 11 parts, Radix Polygoni Multiflori 7 parts, Radix Clematidis 11 parts, the Radix Paeoniae Alba 15 parts, Fructus Tribuli 14 parts, 20 parts of Radix Glycyrrhizae, 20 parts of Radix Rehmanniae Preparata, Periostracum Cicadae 10 parts,
Rhizoma Chuanxiong 13 parts
Other parts of the present embodiment are same as the previously described embodiments, repeat no more.
Embodiment 4
The present embodiment provides this toxicology test being used for alleviating the psoriatic Chinese medicine composition of blood-dryness type, specific as follows:
Acute toxicity test:
Experimental observation, because measuring LD50, therefore has carried out the mensuration of maximum dosage-feeding.Chinese medicine composition prepared by embodiment 1
Thing is dissolved in sterile saline, is configured to solution gavage mice, and result shows, raw with medicine maximum administration concentration 9.65
Medicine/ml, the maximum volume 50ml/kg that is administered were administered twice to mouse stomach in 24 hours, and mice maximum dosage-feeding is 763.25g
Crude drug/kg, there is not untoward reaction and death in animal, anatomic observation each internal organs no abnormality seen.
Long term toxicity test:
This test application SD rat 80, is dissolved in Chinese medicine composition prepared by embodiment 1 in sterile saline, is configured to
Solution gavage, if matched group and 24g, 35g, 49g crude drug/kg dosage group, continuous gastric infusion 12 weeks, observes the Chinese medicine of the present invention
The compositions impact on animal indices.Result of the test shows, successive administration 12 weeks, the Chinese medicine composition of the present invention is to rat
Body weight, food ration, peripheral hemogram, clotting time, electrocardiogram, organ index etc. all have no significant effect；Blood biochemical ten binomial
Index determining result, is administered 12 weeks low dose group BiLi values higher than matched group (P < 0.05)；Low dose group, middle dosage group TP value are high
In matched group (P < 0.05), but all within normal physiologic range, other index compares no significant difference with matched group.Convalescent period
Each administration group indices measured value compares equal no significant difference with matched group.The each internal organs gross examination of skeletal muscle no abnormality seen of each group.
The using method of medicine of the present invention: directly take orally.
Utilize medicine of the present invention for the clinical statistics data of various psoriatics:
Through the Clinical practice of 200 example patients, wherein man patient 114, female patient 86 example, medication age object 20-64 year.Wherein
Minimum 20 years old, maximum 64 years old, 39 years old mean age.
Model case:
1, Liu, man, 32 years old.Before one month extremity stretch the positions such as side occur erythra develop fast band, merge in blocks, general become damp red
Symptom, inflammation is obvious, and squama is many and thick, conscious Pruritus, around with blush around erythra, accompanies dry mouth and parching tongue, urinate red constipation, body of the tongue
Red deep red, few Tianjin of yellow fur, slippery and rapid pulse or stringy and rapid pulse.After the prescription using the embodiment of the present invention 3 takes 13 days orally, temperature recovery is normal, pus
Bleb and skin lesion start to disappear, and area is gradually reduced, and erythema color and luster is thin out, and squama is the most thinning, blood routine examination numeration of leukocyte
Recover to normal range.After 23 days, pustule all disappears, and the 33 days skin erythema squamas that continue to take medicine all disappear, skin smooth,
Only deposit thin pigmentation, recovery from illness.Continue to strengthen and take medicine 10 days, to strengthen curative effect.Recurrence of following up a case by regular visits to that so far there are no.
2, female, 35 years old, suffers from psoriasis 8 years.Nearly 1 year, symptom substantially increased the weight of, and erythema, squama are stretched all over the body, acute pruritus,
Night increases the weight of, and feels depressed, total suspect have people key she, no matter must someone keep company with at daytime, night, go the toilet also must be with
Household, with going, dare not go out, tell outside window and doorway always has stranger and evil spirit to haunt, often shied by nightmare in dream during night
Wake up, scared out of one's wits, dare not sleep again, the state of an illness grows with each passing day, and household is the most agonizing.Within 22nd, examine in JIUYUE in 2013, look into shape
Body is become thin, and mesh is color without god, tried out can't bear, and the whole body spreads all over the erythema that differs in size, overlying lamellar squama, peels off mesh-like seen from squama
Hemorrhage, spread all over scratch, tongue body is thin, the red no fur of matter, thready and rapid pulse.Examine as psoriasis (poison heated contain), because poison fire is disturbed and gods, therefore have
Mental symptoms.For its etiology and pathogenesis, give clearing away heat,cooling blood and removing toxin.The prescription using the embodiment of the present invention 2 is multiple after taking orally 10 days
Looking into, when reflection is taken medicine 4 days, pruritus is more violent, and a lot of tiny erythema, squama occurs again, and within nearly 2 days, pruritus alleviates, erythema, squama
Bits no longer have more, and gradually decrease, and fear still suffers from, but slightly alleviates, and has and wake up with a start time in dream still, but can continue to sleep, and looks into
Erythema color and luster alleviates all over the body, and scratch reduces, and red tongue, thready and rapid pulse, defence is constant.Checking after 20 days, pruritus substantially alleviates all over the body,
Erythema, squama start to reduce, and fear alleviates, and slightly can stable live in the comfort of layman, and household is slightly off a moment also
Not fearing, can go alone toilet, though sleep is the most stable, but not waking up with a start, red tongue, arteries and veins is slightly shown in gentle phase, continues and takes front.
Checking after 30 days, erythema, squama significantly reduce, the whole body the most not pruritus, can treat alone at home daytime, and layman also may be used under accompanying
Short time outdoor activity, sleeps stable, red tongue, and normal pulse delays, and continues and takes front.Checking during 1 first quarter moon, the whole body only has the reddest
Speckle, other skin lesion disappear, the most frightened, and antisecosis is a lot, can individually outdoor activity, it is possible to arbitrarily talk with others,
Red tongue, thin fur, normal pulse delays, because it is sick for a long time, advise its again the side's of taking medicine two weeks check again.Expire check time, the whole body without red
Speckle, squama, skin smooth as before, without frightened, is slept the most stable, can be gone out normally to go to work.
Although an embodiment of the present invention has been shown and described, it will be understood by those skilled in the art that: not
Depart from and these embodiments can be carried out multiple change under the principle of the present invention and objective, revise, replace and modification, the present invention's
Scope is limited by claim and equivalent thereof.
Claims (5)
1. the preparation method being used for alleviating the psoriatic Chinese medicine formula of blood-dryness type, it is characterised in that comprise the following steps:
(1) represent with weight portion, weigh Os Draconis 4-17 part, Concha Ostreae 3-22 part, Carapax et Plastrum Testudinis 5-15 part, Radix Polygoni Multiflori 4-15 part, Radix Clematidis
6-18 part, Radix Paeoniae Alba 5-18 part, Fructus Tribuli 4-16 part, Radix Glycyrrhizae 10-30 part；
(2) by above-mentioned whole raw material of Chinese medicine medicines, to soak 30 minutes with clear water or pure water in advance, water consumption for immersion is 0.9 ~
1.1L；
(3) raw material of Chinese medicine medicine and the liquid medicine of immersion thereof after soaking join in decocting container, add a cover and jointly decoct；
(4) first make decocting container herb liquid seethe with excitement with high heat, re-use slow fire and boil, need to stir when boiling medicine 2 ~ 3 times；
(5) after having decocted, add proper amount of clear water or pure water did not had medicine, carry out second time and decoct, decoct duration and degree of heating method ibid；
(6) leaching medicinal liquid, obtained medicinal liquid is endo-medicine.
A kind of preparation method for alleviating the psoriatic Chinese medicine formula of blood-dryness type the most according to claim 1, its feature
Being, in described step (3), decocting container is marmite, enamel ware, avoids and uses ironware.
A kind of preparation method for alleviating the psoriatic Chinese medicine formula of blood-dryness type the most according to claim 1, its feature
Being, twice decoction in described step (4) and step (5) includes adding for the first time the soak by water 2 hours of 10 times amount, and second time adds
The soak by water of 8 times amount 1 hour.
A kind of preparation method for alleviating the psoriatic Chinese medicine formula of blood-dryness type the most according to claim 1, its feature
Being, in described step (4), slow fire fried time was no less than 30 minutes.
A kind of preparation method for alleviating the psoriatic Chinese medicine formula of blood-dryness type the most according to claim 1, its feature
Being, in described step (6), filtered drug uses filtered through gauze net to filter.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610995442.3A CN106309593A (en) | 2016-11-11 | 2016-11-11 | Preparation method for traditional Chinese medicine formula for relieving dry psoriasis |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610995442.3A CN106309593A (en) | 2016-11-11 | 2016-11-11 | Preparation method for traditional Chinese medicine formula for relieving dry psoriasis |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106309593A true CN106309593A (en) | 2017-01-11 |
Family
ID=57816469
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610995442.3A Withdrawn CN106309593A (en) | 2016-11-11 | 2016-11-11 | Preparation method for traditional Chinese medicine formula for relieving dry psoriasis |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106309593A (en) |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520655A (en) * | 2013-10-25 | 2014-01-22 | 梁轶聪 | Traditional Chinese medicine composition for treating psoriasis vulgaris and preparation method thereof |
| CN105943738A (en) * | 2016-06-08 | 2016-09-21 | 尹晓彤 | Traditional Chinese medicine composition for treating psoriasis |
-
2016
- 2016-11-11 CN CN201610995442.3A patent/CN106309593A/en not_active Withdrawn
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103520655A (en) * | 2013-10-25 | 2014-01-22 | 梁轶聪 | Traditional Chinese medicine composition for treating psoriasis vulgaris and preparation method thereof |
| CN105943738A (en) * | 2016-06-08 | 2016-09-21 | 尹晓彤 | Traditional Chinese medicine composition for treating psoriasis |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102342992B (en) | Chinese medicinal composition for treating insomnia and preparation method of preparation thereof | |
| CN103071128B (en) | Externally-applied plaster for curing dysmenorrhea | |
| CN102205107B (en) | Chinese medicinal preparation for treating duodenal ulcer and preparation method thereof | |
| CN1628760A (en) | Traditional Chinese medicinal formulation for treating cardiovascular and cerebrovascular disease | |
| CN104524481B (en) | A kind of Chinese medicine for treating IBS and preparation method thereof | |
| CN101007159B (en) | Traditional Chinese medicine for preventing and controlling tumor | |
| CN103083616B (en) | Traditional Chinese medicine for treating ovarian cyst | |
| CN103585609A (en) | Traditional Chinese medicine composition for treating dysmenorrhea and preparation method thereof | |
| CN102512645A (en) | Traditional Chinese medicine composition for treating lumbago due to cold dampness | |
| CN100444871C (en) | Atoxic traditional Chinese medicine composition for treating rheumatosis and rheumatoid disease | |
| CN104998074A (en) | Traditional Chinese medicine for treating gastropathy and preparation method thereof | |
| CN106309593A (en) | Preparation method for traditional Chinese medicine formula for relieving dry psoriasis | |
| CN104257813B (en) | A kind of Chinese medicine composition of QI and blood regulating and preparation method thereof | |
| CN103432361B (en) | Chinese medicinal plaster for treating cervical erosion | |
| CN106822852A (en) | Treat pharmaceutical composition, its preparation technology and the purposes of coronary heart disease | |
| CN104840898A (en) | Traditional Chinese medicine composition for treating cholecystitis | |
| CN106309860A (en) | Preparation method for traditional Chinese medicine composition for treating psoriasis | |
| CN106344683A (en) | Preparation method of traditional Chinese medicine composition for eliminating skin erythema and squamae | |
| CN106266001A (en) | One is used for alleviating the psoriatic Chinese medicine formula of blood-dryness type | |
| CN105477384A (en) | Traditional Chinese medicine composition capable of reducing blood pressure and preparation method of composition | |
| CN104800779A (en) | Traditional Chinese medicine preparation for relieving ovary choriocarcinoma and preparation method thereof | |
| CN104225343A (en) | Chinese herbal preparation for treating urinary tract infection and preparation method thereof | |
| CN101618079B (en) | Traditional Chinese medicine for curing hemorrhoids | |
| CN113144148A (en) | Oral and external traditional Chinese medicine for treating liver depression, phlegm dampness and blood stasis type hyperplasia of mammary glands and preparation method thereof | |
| CN112972611A (en) | Pharmaceutical composition for treating hemolytic anemia and application thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| WW01 | Invention patent application withdrawn after publication | ||
| WW01 | Invention patent application withdrawn after publication |
Application publication date: 20170111 |