CN106309244A - Whitening composition containing multiple fresh flowers and preparation method thereof - Google Patents
Whitening composition containing multiple fresh flowers and preparation method thereof Download PDFInfo
- Publication number
- CN106309244A CN106309244A CN201610882488.4A CN201610882488A CN106309244A CN 106309244 A CN106309244 A CN 106309244A CN 201610882488 A CN201610882488 A CN 201610882488A CN 106309244 A CN106309244 A CN 106309244A
- Authority
- CN
- China
- Prior art keywords
- extract
- flower
- lightening compositions
- flos
- stirring
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/67—Vitamins
- A61K8/673—Vitamin B group
- A61K8/675—Vitamin B3 or vitamin B3 active, e.g. nicotinamide, nicotinic acid, nicotinyl aldehyde
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Birds (AREA)
- Dermatology (AREA)
- Epidemiology (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Cosmetics (AREA)
- Medicines Containing Plant Substances (AREA)
Abstract
The invention provides a whitening composition containing multiple fresh flowers and a preparation method thereof. The whitening composition comprises the following components in mass percent: 1.0%-10.0% of butylene glycol, 0.01%-0.8% of xanthan gum, 1.0%-10.0% of sodium lactate, 0.1%-5.0% of panthenol, 0.1%-10.0% of peony extract, 0.1%-10.0% of safflower extract, 0.1%-10.0% of paeonia lactiflora extract, 0.1%-10.0% of peach blossom extract, 0.1%-2.0% of nicotinamide, 0.1%-0.8% of phenoxyethanol, 0.1%-0.8% of caprylyl glycol and balance of de-ionized water. The whitening composition containing multiple fresh flowers provided by the invention not only has low cost, good whitening effect and long acting whitening effect, but also has good moisturizing, inflammation diminishing and soothing effects.
Description
Technical field
The invention belongs to cosmetic technical field, particularly to a kind of lightening compositions containing multiple flower and preparation thereof
Method.
Background technology
" skin such as lipoid, if face Flos persicae ", these two words are usually used to describe beauty, and this U.S.A is also our Aisan one
The straight target pursued.People increasingly pursue healthy pale skin so that the demand of lightening compositions is the biggest.Skin
Color is mainly contained within melanic quantity, size and distribution according to Skin Cell and determines.
In conjunction with the activity problems of tryrosinase, mainly from two Study of ways, one is the damage type suppression of tryrosinase, can
Directly the active site of tryrosinase is modified so that tryrosinase loses the effect to melanocyte precursor-tyrosine；Two
It is the non-damage type suppression of tryrosinase, by the biosynthesis of suppression tryrosinase or by carrying out competing with substrate tyrosine
Strive, thus reach to suppress melanic formation.Secondly melanic transmission should be stoped.Some material can suppress melanin granule
The process shifted to horn cell from melanocyte.Finally, melanic metabolism should be accelerated.It is synthesized at melanin granule
After, on the one hand can be reduced, make the oxidation state melanin granule reduction of black become the reproducibility melanin granule of white,
Secondly, the melanin granule being transferred in skin corium is mainly by the lysosome of cell, by sending out with some enzyme in lysosome
Raw effect, final catabolism falls, so, cell can be stimulated to produce lysosomal material by adding, shorten cutin metabolism
Cycle, thus accelerate cuticular coming off.
The whitening composition used on market by sources divides, and can be divided into plant extract class and synthesis class, and this two big class is beautiful
Bai Chengfen shows respective pluses and minuses, plant extract class natural component safety, effect diversification, but its shortcoming is that cost is remote
Synthesis constituents to be exceeded.And it is low to synthesize constituents general cost, low price, preferable with the compatibility of other compositions, but
Shortcoming is that effect aspect is the most single, effect narrow scope.
Traditional plant extract class whitening composition extracts according to water heating leaching method mostly, this method equipment is simple,
Low cost, easy and simple to handle, but there is active component and destroy the shortcoming big, impurity content is high.
Summary of the invention
The present invention is to make up the some shortcomings that prior art exists, it is provided that a kind of lightening compositions containing multiple flower,
This lightening compositions not only low cost and whitening effect are good, not only have long-acting whitening effect, but also have well guarantor
Wet, antiinflammatory and the effect releived.
The present invention is for reaching its purpose, and the technical scheme of employing is as follows:
A kind of lightening compositions containing multiple flower, including each component of following mass percent: butanediol 1.0%～
10.0%, HANSHENGJIAO 0.01%～0.8%, sodium lactate 1.0%～10.0%, pantothenylol 0.1%～5.0%, Flos Moutan extract
0.1%～10.0%, Flos Carthami extract 0.1%～10.0%, flower of Paeonia lactiflora Pal1. extract 0.1%～10.0%, Flos persicae extract
0.1%～10.0%, nicotiamide 0.1%～2.0%, phenoxyethanol 0.1%～0.8%, caprylyl glycol 0.1%～0.8%, surplus
For deionized water.
Preferably, described Flos Moutan extract, Flos Carthami extract, flower of Paeonia lactiflora Pal1. extract, Flos persicae extract according to include as
Prepared by the method for lower step:
1) petal is ground into unqualified；
2) by step 1) unqualified addition in supercritical extraction reactor, in supercritical extraction reactor, input carbon-dioxide flow
Body, carbon dioxide flow rate is 10～20kg/h, and extracting pressure is 25～30MPa, and extraction temperature is 25-35 DEG C；
3) from supercritical extraction reactor, take out extraction gained mixture, feed the mixture into supercritical separating still, point
Tripping power is 6～8MPa, and temperature is 35～36 DEG C；
4) by step 3) gained separation product is added to the water by solid-liquid ratio 1: 5～15 (unit is g/L), adds thermal distillation 2～4
Hour, recycling of condensed steam obtains extract.
It is further preferred that step 1) in, petal is ground into particle diameter≤80 purpose unqualified.
As a kind of detailed description of the invention, step 2) in, extraction time is 2～4 hours.
As a kind of detailed description of the invention, step 3) in, disengaging time is 1～3 hour.
As a kind of detailed description of the invention, step 4) in, use straight fire to add thermal distillation.
Second aspect present invention provides a kind of method preparing lightening compositions as described above, comprises the steps:
1) HANSHENGJIAO is used butanediol moistening, adds in aqueous phase pot, under stirring, be sequentially added into sodium lactate, pantothenylol,
Deionized water, is warming up to 80 DEG C, and insulation, until being completely dissolved；
2) by step 1) gained mixture sucked in emulsifying pot by vacuum, homogenizing；
3) it is cooled to 40～50 DEG C, nicotiamide is added in emulsifying pot, stirring and evenly mixing；
4) Flos Moutan extract, Flos Carthami extract, flower of Paeonia lactiflora Pal1. extract and Flos persicae extract are added in emulsifying pot, stirring
Mixing；
5) it is cooled to less than 40 DEG C, remaining components is added in emulsifying pot, stirring and evenly mixing.
The technical scheme that the present invention provides has the advantages that
1, the lightening compositions that the present invention provides, several flower extracts therein use the method for optimization of the present invention to prepare
And obtain, substantial amounts of highly purified extract can be extracted rapidly on the premise of not destroying flower active skull cap components, no
Only yield is high, and impurity is few, and extraction process need not use any solvent, the problem stopping dissolvent residual, keeps extracting
The natural characteristic of thing, effective ingredient activity is high.This is compared with tradition flower extraction process, there is clear superiority, and tradition flower carries
Taking technique can lose the active component in flower significantly so that effect of product substantially weakens, and the present invention uses the extraction of optimization
Technique prepares flower extract so that the active component in product obtains the reservation of maximum, and this extracting solution has pleasant sky
So the fragrance of a flower, can substitute traditional synthetic essence completely, and the safety of product also gets a promotion.
Four kinds of flower extract combination collocation prepared by the optimization method using the present invention prepare the present invention's together
Lightening compositions, makes obtained product have good whitening, skin lightening, moisturizing, antiinflammatory, the effect such as releive.
2, the lightening compositions that the present invention provides can suppress the activity of tryrosinase, blocks melanin transport, suppresses black
Chromogenesis, may be used in skin-lightening cosmetic, shows effect of excellence at aspects such as whitening, moisturizing, antioxidation.
3, four kinds of flower extract combination being made an addition in the lightening compositions of the present invention, mutual synergism, by work
Blood, the method accelerating metabolism and suppression tryrosinase carries out whitening, and effect is the most notable.
4, the lightening compositions safety that the present invention provides is high, goes for various people.
5, the flower extract added prepares according to method for optimizing, can retain the natural flavor of flower itself, product
Without to add artificial essence and flavoring agent, the zest of product can be reduced, it is provided that use sensation as snug as a bug in a rug.
6, synthesis whitening composition nicotiamide high with cost performance for the flower whitening composition of natural origin is combined, Ke Yida
To more preferably whitening effect, cost also can control within the scope of reasonably simultaneously.
Accompanying drawing explanation
Fig. 1 is moisturizing test result.
Detailed description of the invention
Below in conjunction with the accompanying drawings technical scheme is described further:
Embodiment 1～3 lightening compositions preparation example of the present invention
Embodiment 1～3 weighs each raw material according to formula as shown in table 1 below.
Table 1 formula table (in table, each numeral is the mass percent in formula)
The lightening compositions of embodiment 1～3 is prepared in accordance with the following steps:
1) by the butanediol moistening of the HANSHENGJIAO in A group, it is subsequently adding in aqueous phase pot, opens stirring, be sequentially added in A group
Other raw materials remaining, are warming up to 80 DEG C, are incubated 10 minutes, until being completely dissolved.
2) mixing speed of emulsifying pot is maintained at 300 revs/min, by step 1) gained mixture sucked by vacuum, low
Speed homogenizing 5 minutes.Start cooling.
3), when dropping to 45 DEG C, each raw material of B group is added in emulsifying pot, open stirring, mix homogeneously；
4) each raw material of C group is sequentially added in emulsifying pot, stirs；
5) stirring is when being cooled to less than 40 DEG C, adds each raw material of D group, stirs 10 minutes until uniform；When being down to 38 DEG C
Filter discharging.
6) check qualified, discharging fill.
Flos Moutan extract in embodiment 1-3, Flos Carthami extract, flower of Paeonia lactiflora Pal1. extract, Flos persicae extract respectively according to
Prepared by following steps:
1), select that high-quality is fresh, complete and pure fresh petal, after cleaning up with pure water, put into reducing mechanism
It is ground into particle diameter≤80 purpose unqualified；
2), material powder is transported in supercritical extraction reactor, input CO in supercritical extraction reactor2Fluid, CO2Flow velocity
For 15kg/h, extracting pressure is adjusted to 28MPa, extraction temperature is to extract at 30 DEG C, extracts 3 hours；
3), take out extraction mixture from supercritical extraction reactor outlet, mixture is input in supercritical separating still, separates
Pressure is adjusted to 6～8MPa, temperature is 35～36 DEG C, separates 2 hours；
4), be that 1: 10 (unit is g/L) is added to the water the above product that separates by solid-liquid ratio, straight fire adds thermal distillation 3 hours,
Steam condensation recovery obtains flower extract.
Reference examples 1～3
Reference examples 1～3 weighs each component according to formula shown in table 1；
The preparation method of reference examples 1～3 lightening compositions, with reference to embodiment 1～the carrying out of 3, repeats no more.
Efficacy test
One, long-acting whitening effect evaluation
Test sample: embodiment 1, embodiment 2, embodiment 3, reference examples 1, reference examples 2, reference examples 3
Test purpose: used skin-protection product by adult female volunteer the most continuously, is assessed this skin protection and produces
Product effect in terms of whitening.
Volunteer's age: 25～44 years old
Sex: women
Volunteer's number: 180 people
Volunteer's face skin quality: blee is obscure, matt
Whitening effect: buccal
Product uses frequency: uniform application after face cleaning, every day 2 times, the most once, produce with using after using product surrounding
After product eight weeks.
Test event: long-acting whitening effect
Appraisal procedure: use the mode of questionnaire survey, understands experimenter in 4 weeks and 8 weeks after using product and uses product
The evaluation of the improvement situation of the rear colour of skin.Judging quota is broadly divided into: whitening effect.Result is divided into: DeGrain, effect one
As, more apparent, clearly.
1) after, using product surrounding
Experiment conclusion:
The whitening effect statistics that each experimental group volunteer tries out 28 days shows:
In 30 volunteers using embodiment 1, the volunteer of 50% is had to feel to have obviously whitening effect.
In 30 volunteers using embodiment 2, the volunteer of 53.3% is had to feel to have obviously whitening effect.
In 30 volunteers using embodiment 3, the volunteer of 60% is had to feel to have obviously whitening effect.
In 30 volunteers using reference examples 1, the volunteer of only 20% feels to have obviously whitening effect.
In 30 volunteers using reference examples 2, the volunteer of only 10% feels to have obviously whitening effect.
In 30 volunteers using reference examples 3, the volunteer of only 13.3% feels to have obviously whitening to imitate
Really.
Result shows, the embodiment 1～4 cleawhite over-night essences containing four kinds of flower extracting solution, whitening effect is substantially better than right
As usual.
2), use product after eight weeks
Experiment conclusion:
Use the volunteer of cleawhite over-night essences, the whitening effect statistics display of 56 days:
In 30 volunteers using embodiment 1, the volunteer of 56.7% is had to feel to have obviously whitening effect.
In 30 volunteers using embodiment 2, the volunteer of 60% is had to feel to have obviously whitening effect.
In 30 volunteers using embodiment 3, the volunteer of 66.7% is had to feel to have obviously whitening effect.
In 30 volunteers using reference examples 1, the volunteer of only 20% feels to have obviously whitening effect.
In 30 volunteers using reference examples 2, the volunteer of only 10% feels to have obviously whitening effect.
In 30 volunteers using reference examples 3, the volunteer of only 10% feels to have obviously whitening effect.
Result shows, the embodiment 1-3 cleawhite over-night essences containing four kinds of flower extracting solution, whitening effect is substantially better than comparison
Example.
Two, performance of keeping humidity assessment
Appraisal procedure:
1) tested material: embodiment 1, embodiment 2, embodiment 3, reference examples 1
2) experimenter: totally 30 people, male 10 people, female 20 people, age 21～49 years old, meet experimenter and volunteer inclusion criteria.
3) appraisal procedure: the sample of 70ul is applied to two wrist medial parts.Front conductivity measured value will be smeared and be set to 1, see
Examine before smearing, 5,15,30,60 minutes change in values after smearing.Evaluate the moisture retention of sample successively.
4) assessment result: observing the change in value of conductivity, result is as shown in Figure 1.
Experiment conclusion: test result indicate that, the moisture retention after embodiment 1,2,3 is smeared is significantly higher than reference examples 1.
During carrying out efficacy test, user all represents that the product of embodiment of the present invention 1-3 has the pleasant fragrance of a flower,
And product uses gentle as snug as a bug in a rug, do not find any allergy or stimulate phenomenon.
The above, be only presently preferred embodiments of the present invention, and the present invention not does any pro forma restriction, therefore
All contents without departing from technical solution of the present invention, any simply repair made for any of the above embodiments according to the technical spirit of the present invention
Change, equivalent variations and modification, all still fall within the range of technical solution of the present invention.
Claims (7)
1. the lightening compositions containing multiple flower, it is characterised in that include each component of following mass percent: fourth two
Alcohol 1.0%～10.0%, HANSHENGJIAO 0.01%～0.8%, sodium lactate 1.0%～10.0%, pantothenylol 0.1%～5.0%, Paeonia suffruticosa
Flower extract 0.1%～10.0%, Flos Carthami extract 0.1%～10.0%, flower of Paeonia lactiflora Pal1. extract 0.1%～10.0%, Flos persicae
Extract 0.1%～10.0%, nicotiamide 0.1%～2.0%, phenoxyethanol 0.1%～0.8%, caprylyl glycol 0.1%～
0.8%, surplus is deionized water.
Lightening compositions the most according to claim 1, it is characterised in that described Flos Moutan extract, Flos Carthami extract, Chinese herbaceous peony
Medicine flower extract or Flos persicae extract are prepared according to the method comprised the steps:
1) petal is ground into unqualified；
2) by step 1) unqualified addition in supercritical extraction reactor, in supercritical extraction reactor, input CO 2 fluid, two
Carbonoxide flow velocity is 10～20kg/h, and extracting pressure is 25～30MPa, and extraction temperature is 25～35 DEG C；
3) from supercritical extraction reactor, take out extraction gained mixture, feed the mixture into supercritical separating still, separate pressure
Power is 6～8MPa, and temperature is 35～36 DEG C；
4) by step 3) gained separation product is added to the water by solid-liquid ratio 1: 5～15 (unit is g/L), adds thermal distillation 2～4 little
Time, recycling of condensed steam obtains extract.
Lightening compositions the most according to claim 2, it is characterised in that step 1) in, petal is ground into particle diameter≤80
Purpose is unqualified.
Lightening compositions the most according to claim 2, it is characterised in that step 2) in, extraction time is 2～4 hours.
Lightening compositions the most according to claim 2, it is characterised in that step 3) in, disengaging time is 1～3 hour.
Lightening compositions the most according to claim 2, it is characterised in that step 4) in, use straight fire to add thermal distillation.
7. the method for the lightening compositions prepared as described in any one of claim 1～6, it is characterised in that include as follows
Step:
1) HANSHENGJIAO is used butanediol moistening, adds in aqueous phase pot, under stirring, be sequentially added into sodium lactate, pantothenylol, go from
Sub-water, is warming up to 80 DEG C, and insulation, until being completely dissolved；
2) by step 1) gained mixture sucked in emulsifying pot by vacuum, homogenizing；
3) it is cooled to 40～50 DEG C, nicotiamide is added in emulsifying pot, stirring and evenly mixing；
4) adding in emulsifying pot by Flos Moutan extract, Flos Carthami extract, flower of Paeonia lactiflora Pal1. extract and Flos persicae extract, stirring is mixed
Even；
5) it is cooled to less than 40 DEG C, remaining components is added in emulsifying pot, stirring and evenly mixing.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610882488.4A CN106309244B (en) | 2016-10-09 | 2016-10-09 | It is a kind of containing there are many lightening compositions of fresh flower and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610882488.4A CN106309244B (en) | 2016-10-09 | 2016-10-09 | It is a kind of containing there are many lightening compositions of fresh flower and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106309244A true CN106309244A (en) | 2017-01-11 |
| CN106309244B CN106309244B (en) | 2019-04-16 |
Family
ID=57821365
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610882488.4A Active CN106309244B (en) | 2016-10-09 | 2016-10-09 | It is a kind of containing there are many lightening compositions of fresh flower and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106309244B (en) |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108379182A (en) * | 2018-05-31 | 2018-08-10 | 傅清杰 | A Chinese medicine functional mask |
| CN110613650A (en) * | 2019-10-25 | 2019-12-27 | 上海伽誉生物科技有限公司 | Essence containing okra hydrolyzed glycoprotein SILKY-WSP and preparation method thereof |
| CN110693780A (en) * | 2019-10-31 | 2020-01-17 | 广东密尚生物科技有限公司 | Skin nourishing composition and application thereof, and skin nourishing mask liquid |
Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003012495A (en) * | 2001-07-06 | 2003-01-15 | Kanebo Ltd | Cosmetic |
| CN103830137A (en) * | 2014-01-20 | 2014-06-04 | 上海珈叶生物技术有限公司 | Plant extract composition with whitening effect, preparation and preparation method thereof |
-
2016
- 2016-10-09 CN CN201610882488.4A patent/CN106309244B/en active Active
Patent Citations (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JP2003012495A (en) * | 2001-07-06 | 2003-01-15 | Kanebo Ltd | Cosmetic |
| CN103830137A (en) * | 2014-01-20 | 2014-06-04 | 上海珈叶生物技术有限公司 | Plant extract composition with whitening effect, preparation and preparation method thereof |
Non-Patent Citations (1)
| Title |
|---|
| 姚九莲: "《中药外用指南》", 31 May 2010, 金盾出版社 * |
Cited By (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108379182A (en) * | 2018-05-31 | 2018-08-10 | 傅清杰 | A Chinese medicine functional mask |
| CN110613650A (en) * | 2019-10-25 | 2019-12-27 | 上海伽誉生物科技有限公司 | Essence containing okra hydrolyzed glycoprotein SILKY-WSP and preparation method thereof |
| CN110693780A (en) * | 2019-10-31 | 2020-01-17 | 广东密尚生物科技有限公司 | Skin nourishing composition and application thereof, and skin nourishing mask liquid |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106309244B (en) | 2019-04-16 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN103494754B (en) | Hair-loss preventing and hair-restoring shampoo of herbal essences and biochemical component formula and preparation method thereof | |
| CN103705414B (en) | A kind of eye cream | |
| CN103784365B (en) | Skin whitener and preparation method thereof | |
| CN106309244A (en) | Whitening composition containing multiple fresh flowers and preparation method thereof | |
| CN102754756A (en) | Natural plant feed additive for improving tear stains of poodles and preparation method thereof | |
| JP5117061B2 (en) | Moisturizing composition | |
| CN103083213A (en) | Acer truncatum oil skincare cream and preparation method thereof | |
| CN105902478A (en) | Moisturizing anti-aging cosmetic containing cedrela sinensis extract and preparation method of moisturizing anti-aging cosmetic | |
| CN102058513B (en) | Chinese herbal medicine crude solution and cosmetic containing same | |
| CN102755280B (en) | Chinese herbal medicine shampoo and preparation method thereof | |
| CN106236676A (en) | A kind of vegetable composition with senile-resistant efficacy and application thereof | |
| CN109223686A (en) | A kind of light formula of bath cream with moistening skin-care function | |
| CN105998652A (en) | Traditional Chinese medicine composition and application and preparation thereof | |
| CN104873433A (en) | Moxa skin cream and preparing method thereof | |
| AU2011358953B2 (en) | Hair growth agent / hair tonic | |
| CN105342966B (en) | Skin care moisturiser containing Hirudo japonica and preparation method thereof | |
| CN105476895B (en) | A kind of hair-washing composition containing lotus active constituent | |
| CN106119044A (en) | A kind of looks improving and the skin nourishing cider and preparation method thereof | |
| CN109971567A (en) | A kind of Chinese medicine cosmetic perfumed soap and preparation method thereof | |
| CN104706566A (en) | Pawpaw seed oil antiwrinkling sleeping mask and preparation method thereof | |
| CN102475649A (en) | Radix Trichosanthis nutritional skin care lotion | |
| CN108210433A (en) | Cardamom skin care compositions and its application with oil-control and/or acne-removing | |
| JP2008001666A (en) | Moisture-keeping composition | |
| CN110585074B (en) | Application of rose essential oil balm in cosmetics | |
| CN112156048A (en) | Natural whitening face cleaning powder and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| PB01 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20190926 Address after: Room 204, Building 5, Dingye Group, No. 9 Xinglong Road, Pukou District, Nanjing City, Jiangsu Province, 210000 Patentee after: Nanjing Miaochuntang Pharmaceutical Technology Co.,Ltd. Address before: 510000 Tianhe District, Guangdong Tianhe East Road, No. 240, No. Patentee before: GUANGZHOU ZHIYUAN BIOTECHNOLOGY CO.,LTD. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20201228 Address after: Room 904, Dingye group, No.9, Xinglong Road, Pukou District, Nanjing City, Jiangsu Province, 210000 Patentee after: Hangfu (Nanjing) Biomedical Technology Co.,Ltd. Address before: Room 204, building 5, Dingye group, 9 Xinglong Road, Pukou District, Nanjing City, Jiangsu Province, 210000 Patentee before: Nanjing Miaochuntang Pharmaceutical Technology Co.,Ltd. |
|
| TR01 | Transfer of patent right | ||
| TR01 | Transfer of patent right |
Effective date of registration: 20220708 Address after: 210000 room 208, 2nd floor, dingmeng e-commerce Pioneer Park, 101 Tianhua East Road, Yanjiang street, Jiangbei new district, Nanjing City, Jiangsu Province Patentee after: Nanjing Miaochuntang Pharmaceutical Technology Co.,Ltd. Address before: Room 904, Dingye group, No.9, Xinglong Road, Pukou District, Nanjing City, Jiangsu Province, 210000 Patentee before: Hangfu (Nanjing) Biomedical Technology Co.,Ltd. |