CN106290934A - The process of specimen, transport and detection method - Google Patents

The process of specimen, transport and detection method Download PDF

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Publication number
CN106290934A
CN106290934A CN201510304590.1A CN201510304590A CN106290934A CN 106290934 A CN106290934 A CN 106290934A CN 201510304590 A CN201510304590 A CN 201510304590A CN 106290934 A CN106290934 A CN 106290934A
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China
Prior art keywords
specimen
lid
storage pipe
detection
sampling rod
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CN201510304590.1A
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CN106290934B (en
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陈国治
姚恺龄
徐琪
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YISIMEIQUAN BIOLOGICAL SCIENCE AND TECHNOLOGY (SHANGHAI) Co Ltd
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YISIMEIQUAN BIOLOGICAL SCIENCE AND TECHNOLOGY (SHANGHAI) Co Ltd
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Publication of CN106290934A publication Critical patent/CN106290934A/en
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Abstract

The invention discloses the process of a kind of specimen, transport and detection method, the first step, use sampling rod collect specimen;Second step, outwards winding the lid of specimen storage pipe, is stretched into by sampling rod in the body of specimen storage pipe;3rd step, by sampling rod indwelling in the body of specimen storage pipe;4th step, the specimen storage pipe that will be equipped with sampling rod is inverted and is transported above detection card;5th step, makes the specimen fluids in specimen storage pipe all be clamp-oned the sample receiving trough of detection card by water dropper, makes specimen fluids enter in multiple detection grooves of detection card.The sampling method of the present invention, the dropping of specimen fluids can be completed by the extrusion action in specimen storage pipe, it is not necessary to uses expensive sample needle to carry out the dropping of specimen fluids, it is possible to saves sampling cost;After specimen fluids extrusion from specimen storage pipe, specimen storage pipe with low cost can be abandoned, eliminate the cleaning to sample needle, alleviate the workload of operator.

Description

The process of specimen, transport and detection method
Technical field
The present invention relates to the processing method of a kind of specimen, be specifically related to the process of a kind of specimen, transport and detection method.
Background technology
At present, fast detection method has been widely used in industry-by-industry and field.In order to meet the facility and accurately of detection operation, And the demand to the analysis of big specimen batch detection, increasing professional person has been developed over all kinds of automatic detection analysis instrument, For to separate sources (as from environment, food, biological tissue etc.), the sample of different shape (solid-state, semisolid, liquid) Originally a series of full-automatic or semi-automatic Treatment Analysis activity is carried out, including sample disposal, Samples detection, interpretation of result with sentence Read, result exports printing etc..
Existing automatic detection analysis instrument, needs to use peristaltic pump or ceramic pump accurate measuring liquid, with sample needle to move accurately Work and capacity carry out absorption and the dropping of plurality of liquid.In order to avoid the cross-contamination between sample and between step, automatic detection analysis Instrument need to use multiple sample needle, or arrange and loaded down with trivial details wash pin program, and this can increase the cost of equipment itself undoubtedly.It addition, such as Fruit has the demand of multiple detection, and these instruments also need to arrange the replacement space of multiple detection device, store and operate, and this is also It it is the reason improving equipment cost.
Summary of the invention
The technical problem to be solved is to provide the process of a kind of specimen, transport and detection method, and it can save sampling Cost, improves sampling precision, improves sampling efficiency, and reduces equipment cost.
For solving above-mentioned technical problem, the technical solution of the process of specimen of the present invention, transport and detection method is:
The first step, uses sampling rod 25 collect specimen, makes the head of sampling rod 25 with specimen;
Second step, outwards winding the lid 22 filling the specimen storage pipe of diluent 24, sampling rod 25 is stretched into specimen storage pipe In body 21, the specimen of sampling rod 25 head is made to immerse the diluent 24 in body 21;
3rd step, rotates sampling rod 25 and makes the specimen of its head fully mix with the diluent 24 in body 21;By sampling rod 25 indwellings are in the body 21 of specimen storage pipe;Then the lid 22 covering specimen storage pipe makes it seal;
4th step, opens the water dropper lid 23 of specimen storage pipe, and the specimen storage pipe that will be equipped with sampling rod 25 is inverted, by mechanical hand Above transport to detection blocks;
5th step, presses the body 21 of specimen storage pipe by mechanical hand from both sides, makes the specimen fluids in specimen storage pipe by dripping Head 22-2 is all clamp-oned the sample receiving trough 32 of detection card, and specimen fluids is uniform to multiple detection grooves 33 through groove 34 from sample receiving trough 32 Diffusion, makes specimen fluids enter in multiple detection grooves 33 of detection card.
The length of described sampling rod 25 is more than the length of specimen storage pipe;Described 3rd step rotates sampling rod 25 makes the mark of its head After this fully mixes with the diluent 24 in body 21, being blocked by the afterbody of sampling rod 25, the residue making sampling rod 25 is long Degree is slightly less than body 21 length of specimen storage pipe, then by sampling rod 25 indwelling in the body 21 of specimen storage pipe.
Described sampling rod 25 is single head aseptic cotton carrier or sterile swab.
Described specimen is liquid, semisolid or solid thing to be checked.
Described specimen storage pipe includes a soft body 21, and the head of body 21 is threaded connection lid 22;Lid 22 includes Lid 22-1, the lower end of lid 22-1 is provided with female thread, the external screw thread phase of the female thread of lid 22-1 and body 21 head Coordinate, it is achieved threadeding between lid 22 and the head of body 21;The head of lid 22-1 forms a thin tube-like water dropper 22-2, water dropper 22-2 are threaded connection water dropper lid 23;Water dropper 22-2 is provided with external screw thread, the external screw thread of water dropper 22-2 with The female thread of water dropper lid 23 matches, it is achieved threadeding between water dropper 22-2 with water dropper lid 23;In described body 21 in advance Equipped with sample diluent;The hydrophobic filter paper of at least one of which 24 it is provided with in described lid 22-1.
Described detection card includes base 31, and base 31 offers a sample receiving trough 32, and the distributed about of sample receiving trough 32 has multiple inspection Surveying groove 33, multiple detection grooves 33 are distributed on same circumference, and sample receiving trough 32 is centrally located at the circle of detection groove 33 place circumference The heart;It is respectively arranged with groove 34, so that sample receiving trough 32 is connected with detection groove 33 between each detection groove 33 and sample receiving trough 32.
The sample receiving trough 32 of described detection card is circular, square, triangle or ellipse.
The detection groove 33 of described detection card is circular, square, triangle or ellipse.
The body 21 of described specimen storage pipe is elastomer.
The diameter of the water dropper 22-2 of the described specimen storage pipe diameter less than lid 22-1.
What the present invention can reach has the technical effect that
In the present invention, the sample diluent in specimen memotron is carried out inoculated by machine, and the volume of diluent is accurately controlled by machine System, it is not necessary to doctor's craft liquid feeding, can either ensure that the volume of diluent is accurate, can remove again doctor from and drip the hardship of liquid by hand, Save doctor's time.
Collection is had the sampling rod indwelling of specimen in specimen storage pipe by the present invention, can not only ensure the specimen that sampling rod is gathered Farthest extract in diluent, and during by specimen storage pipe by sampling at transport extremely detection card, will mark This is sealed in specimen storage pipe together with sampling rod, it is possible to thoroughly stop the pollution to specimen in transportation.
The present invention only need to once extrude action, and the liquid in specimen storage pipe is clamp-oned the sample receiving trough of detection card, and liquid can enter automatically Enter multiple detection groove, it is achieved the dropping to multiple detection grooves, it is not necessary to repeatedly drip action such that it is able to be greatly saved sample time, Improve sampling efficiency.
In the present invention, transport and the specimen fluids extrusion action from specimen storage pipe of specimen memotron are complete by automated machine equipment Become, it is possible to reduce the impact on testing result of the manpower factor.
In the present invention, the dropping of specimen fluids can be completed by the extrusion action in specimen storage pipe, it is not necessary to uses expensive sample-adding Pin carries out absorption and the dropping of specimen fluids, it is possible to be substantially reduced the cost of automatic analyzer;Specimen fluids is from specimen storage pipe After extrusion, discardable specimen storage pipe with low cost, eliminate the cleaning step to sample needle, not only shorten sample time, And avoid because cleaning cross-contamination between the specimen that syringe needle the most thoroughly causes.
After in the present invention, specimen fluids is extracted from specimen storage pipe, no liquid residual in specimen storage pipe, it is not necessary to worry residue mark Outside the outer discharger of this liquid.
Accompanying drawing explanation
The present invention is further detailed explanation with detailed description of the invention below in conjunction with the accompanying drawings:
Fig. 1 is the schematic diagram of the specimen storage pipe of the present invention;
Fig. 2 to Fig. 4 is the process schematic of the process of specimen of the present invention, transport and detection method;
Fig. 5 is the schematic diagram of the detection card of the present invention.
Fig. 6 is the schematic diagram of another embodiment of the detection card of the present invention;
Fig. 7 is the schematic diagram of the 3rd embodiment of the detection card of the present invention.
Description of reference numerals in figure:
11 is sampling swab, and 12 is sample-adding test tube,
13 is diluent, and 14 is base,
15 is detection groove,
21 is body, and 22 is lid,
22-1 is lid, and 22-2 is water dropper,
23 is water dropper lid, and 24 is diluent,
25 is sampling rod,
31 is base, and 32 is sample receiving trough,
33 is detection groove, and 34 is groove.
Detailed description of the invention
The process of specimen of the present invention, transport and detection method, comprise the following steps:
The first step, uses sampling rod 25 collect specimen that can break, makes the head of sampling rod 25 with specimen;Sampling rod 25 Length is more than the length of specimen storage pipe;
Sampling rod 25 can be single head aseptic cotton carrier or sterile swab;Specimen can be liquid or solid secretions;
Second step, outwards winding the lid 22 filling the specimen storage pipe of sample diluent 24, sampling rod 25 is stretched into specimen storage In the body 21 of pipe, the specimen of sampling rod 25 head is made to immerse the diluent 24 in body 21, as shown in Figure 2;
3rd step, rotates sampling rod 25 and makes the specimen of its head fully mix with the diluent 24 in body 21;Then will sampling The afterbody of rod 25 is broken, and makes the residue length of sampling rod 25 be slightly less than body 21 length of specimen storage pipe, and by sampling rod 25 indwellings are in the body 21 of specimen storage pipe, as shown in Figure 3;Then the lid 22 covering specimen storage pipe makes it seal, As shown in Figure 4;
The upper semisection of the sampling bar cut down abandons;
4th step, opens the water dropper lid 23 of specimen storage pipe, and (i.e. water dropper 22-2 is inverted by the specimen storage pipe that will be equipped with sampling rod 25 Down) and put in vaginitis automatic detection analysis instrument (for prior art), above by mechanical hand transport to detection card;
5th step, is pressed the body 21 of specimen storage pipe, makes specimen by the mechanical hand of vaginitis automatic detection analysis instrument from both sides Liquid (i.e. specimen fluids) in memotron is all clamp-oned the sample receiving trough 32 that detection blocks, specimen fluids by water dropper 22-2 by disposable Uniformly spreading to multiple detection grooves 33 through groove 34 from sample receiving trough 32, specimen fluids automatically flows into multiple detection grooves 33 of detection card In;
Multiple detection grooves 33 are respectively used to detect following index: hydrogen peroxide (H2O2), leukocyte esterase (LE), saliva Anhydride enzyme (SNA), GRD beta-glucuronidase, acetyl glucosaminidase (NAG), pH value.
As it is shown in figure 1, the specimen storage pipe of the present invention, including a resilient soft body 21 of tool, the head of body 21 leads to Cross threaded lid 22;Can deform upon after body 21 stress, not stress, restore to the original state;
Lid 22 includes that lid 22-1, the lower end of lid 22-1 are provided with female thread, the female thread of lid 22-1 and body 21 The external screw thread of head matches, it is achieved threadeding between lid 22 and the head of body 21;
The head of lid 22-1 forms a thin tube-like water dropper 22-2, and water dropper 22-2 is threaded connection water dropper lid 23;
Water dropper 22-2 is provided with external screw thread, and the external screw thread of water dropper 22-2 matches with the female thread of water dropper lid 23, it is achieved water dropper Threadeding between 22-2 with water dropper lid 23;
The hydrophobic filter paper of at least one of which 24 it is provided with in lid 22-1;When specimen storage pipe is inverted, body 21 is not pressed, dredge Water filter paper 24 can block the specimen fluids in pipe and will not automatically flow out;And when specimen storage pipe is inverted and body 21 is depressed, Hydrophobic filter paper 24 can intercept the solid in specimen fluids and semi-solid material.
As shown in Figures 5 to 7, the detection card of the present invention, including base 31, base 31 offers one and open-topped connects Sample groove 32, the distributed about of sample receiving trough 32 has multiple (generally four or six) open-topped detection groove 33, Duo Gejian Surveying groove 33 to be distributed on same circumference, sample receiving trough 32 is centrally located at the center of circle of detection groove 33 place circumference;Each detection groove Groove 34 it is respectively arranged with, so that sample receiving trough 32 is connected with detection groove 33 between 33 and sample receiving trough 32;
Sample receiving trough 32 can be circular, square, triangle or ellipse;
Detection groove 33 can be circular, square, triangle or ellipse.
The detection card of the present invention, its multiple detection grooves are distributed on same circumference, and sample receiving trough is centrally located at detection groove place circumference The center of circle so that the liquid in sample receiving trough can be with identical speed automatically into each detection groove, so that the respectively mark in detection groove This volume is identical.
Specimen mentioned by Ben Wen, can be biological sample (such as secretions), it is also possible to be food, it is also possible to be water quality water sample etc..

Claims (10)

1. the process of a specimen, transport and detection method, it is characterised in that comprise the following steps:
The first step, uses sampling rod collect specimen, makes the head of sampling rod with specimen;
Second step, outwards winding the lid filling the specimen storage pipe of diluent, is stretched into by sampling rod in the body of specimen storage pipe, Make the diluent in the specimen immersion pipe body of sampling rod head;
3rd step, rotates sampling rod and makes the specimen of its head fully mix with the diluent in body;By sampling rod indwelling in specimen In the body of memotron;Then the lid covering specimen storage pipe makes it seal;
4th step, opens the water dropper lid of specimen storage pipe, will be equipped with sampling rod specimen storage pipe be inverted, by mechanical hand transport to Above detection card;
5th step, presses the body of specimen storage pipe by mechanical hand from both sides, makes the specimen fluids in specimen storage pipe pass through water dropper All being clamp-oned the sample receiving trough of detection card, specimen fluids uniformly spreads to multiple detection grooves through groove from sample receiving trough, makes specimen fluids enter In multiple detection grooves of detection card.
The process of specimen the most according to claim 1, transport and detection method, it is characterised in that described sampling rod Length is more than the length of specimen storage pipe;The specimen that described 3rd step rotation sampling rod makes its head is abundant with the diluent in body After mixing, the afterbody of sampling rod is blocked, make the residue length of sampling rod be slightly less than the tube length of specimen storage pipe, then By sampling rod indwelling in the body of specimen storage pipe.
The process of specimen the most according to claim 1, transport and detection method, it is characterised in that described sampling rod is Single head aseptic cotton carrier or sterile swab.
The process of specimen the most according to claim 1, transport and detection method, it is characterised in that described specimen is liquid Body, semisolid or solid thing to be checked.
The process of specimen the most according to claim 1, transport and detection method, it is characterised in that described specimen storage Pipe includes a body, and the head of body is threaded connection lid;
Lid includes lid, and the lower end of lid is provided with female thread, and the female thread of lid matches with the external screw thread of body head, Realize threadeding between lid and the head of body;
The head of lid forms a thin tube-like water dropper, and water dropper is threaded connection water dropper lid;
Water dropper is provided with external screw thread, and the external screw thread of water dropper matches with the female thread of water dropper lid, it is achieved between water dropper and water dropper lid Threaded;
The hydrophobic filter paper of at least one of which it is provided with in described lid.
The process of specimen the most according to claim 1, transport and detection method, it is characterised in that described detection Ka Bao Including base, base offers a sample receiving trough, the distributed about of sample receiving trough has multiple detection groove, and multiple detection grooves are distributed in same On circumference, sample receiving trough is centrally located at the center of circle of detection groove place circumference;It is respectively arranged with ditch between each detection groove and sample receiving trough Groove, so that sample receiving trough is connected with detection groove.
The process of specimen the most according to claim 6, transport and detection method, it is characterised in that described detection card Sample receiving trough is circular, square, triangle or ellipse.
The process of specimen the most according to claim 6, transport and detection method, it is characterised in that described detection card Detection groove is circular, square, triangle or ellipse.
The process of specimen the most according to claim 1, transport and detection method, it is characterised in that described specimen storage The body of pipe is elastomer.
The process of specimen the most according to claim 1, transport and detection method, it is characterised in that described specimen storage The diameter of the water dropper of pipe is less than the diameter of lid.
CN201510304590.1A 2015-06-04 2015-06-04 Processing, transport and the detection method of sample Active CN106290934B (en)

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Application Number Priority Date Filing Date Title
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CN106290934B CN106290934B (en) 2018-06-29

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106970218A (en) * 2017-05-27 2017-07-21 深圳市瀚德标检生物工程有限公司 A kind of vaginitis self-test device
CN113281145A (en) * 2021-05-24 2021-08-20 厦门小竺医疗器械有限公司 Reagent pre-filled storage tube for detection and detection method
CN114459819A (en) * 2022-02-09 2022-05-10 中国人民解放军军事科学院军事医学研究院 Sample dilution tube and sampling kit using same

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1985174A (en) * 2004-07-12 2007-06-20 爱科来株式会社 Analyzer, method for specifying reaction vessel in analyzer, and analytical apparatus
CN102321731A (en) * 2011-07-08 2012-01-18 江苏硕世生物科技有限公司 Vaginitis detection kit and preparation method thereof
CN203376333U (en) * 2013-07-26 2014-01-01 天津微纳芯科技有限公司 Multifunctional integrated chip for multi-index detection
CN203658364U (en) * 2013-12-27 2014-06-18 益思美诠生物科技(上海)有限公司 Specimen treatment device for detecting chlamydia antigen

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1985174A (en) * 2004-07-12 2007-06-20 爱科来株式会社 Analyzer, method for specifying reaction vessel in analyzer, and analytical apparatus
CN102321731A (en) * 2011-07-08 2012-01-18 江苏硕世生物科技有限公司 Vaginitis detection kit and preparation method thereof
CN203376333U (en) * 2013-07-26 2014-01-01 天津微纳芯科技有限公司 Multifunctional integrated chip for multi-index detection
CN203658364U (en) * 2013-12-27 2014-06-18 益思美诠生物科技(上海)有限公司 Specimen treatment device for detecting chlamydia antigen

Cited By (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106970218A (en) * 2017-05-27 2017-07-21 深圳市瀚德标检生物工程有限公司 A kind of vaginitis self-test device
CN106970218B (en) * 2017-05-27 2020-01-03 深圳市瀚德标检生物工程有限公司 Vaginitis self-detection device
CN113281145A (en) * 2021-05-24 2021-08-20 厦门小竺医疗器械有限公司 Reagent pre-filled storage tube for detection and detection method
CN114459819A (en) * 2022-02-09 2022-05-10 中国人民解放军军事科学院军事医学研究院 Sample dilution tube and sampling kit using same
CN114459819B (en) * 2022-02-09 2024-05-03 中国人民解放军军事科学院军事医学研究院 Sample diluting tube and sampling kit using same

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