CN106234382B - A kind of bactericidal composition and its fungicide containing Thiodiazole-copper and shenqinmycin - Google Patents
A kind of bactericidal composition and its fungicide containing Thiodiazole-copper and shenqinmycin Download PDFInfo
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- CN106234382B CN106234382B CN201610715788.3A CN201610715788A CN106234382B CN 106234382 B CN106234382 B CN 106234382B CN 201610715788 A CN201610715788 A CN 201610715788A CN 106234382 B CN106234382 B CN 106234382B
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- thiodiazole
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/82—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with three ring hetero atoms
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/48—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with two nitrogen atoms as the only ring hetero atoms
- A01N43/60—1,4-Diazines; Hydrogenated 1,4-diazines
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Abstract
The present invention relates to a kind of bactericidal composition and its fungicide containing Thiodiazole-copper and shenqinmycin.The active constituent of a kind of bactericidal composition containing Thiodiazole-copper and shenqinmycin of the present invention, bactericidal composition is Thiodiazole-copper and shenqinmycin.Advantage is：The bactericidal composition can be superimposed synergy, promote mutually, play the advantage of the two well, have synergistic function；It being capable of a variety of root soil-borne diseases of integrated control.Bacterial disease and fungal disease can be prevented simultaneously, are reached a medicine and are controlled more, save spraying time and formulation rate, reduce labor intensity.
Description
Technical field
The invention belongs to pesticide fields, are related to a kind of bactericidal composition for preventing agricultural disease, more particularly to a kind of
Bactericidal composition containing Thiodiazole-copper and shenqinmycin and its fungicide.
Background technology
Current agriculture field makes part bacterium and fungal disease due to single drug and other unscientific application methods
Drug resistance is produced to many medicaments, becomes a great problem in agriculture sterilization process.Since germ generates resistance, peasant is frequent
Dispenser causes drug cost increase and increasing environmental pollution again.Some efficient pharmaceutical preparations, if long-term single use, also face
Face the risk to develop immunity to drugs, in addition, medicament newly developed is due to price height, it is difficult to popularize application in an all-round way on the market.Cause
This, search out efficiently, wide sterilization spectrum, at low cost and environmentally friendly disinfecting combine to cope with the drug resistance of disease, become ability
Field technique personnel's urgent problem to be solved.
Thiodiazole-copper is the innovative pesticide that applicant's independent research is designed and promoted, and is domestic initiation, and has formerly been obtained
National inventing patent mandate (ZL99113411.7).The structural formula of Thiodiazole-copper is as follows：
Thiodiazole-copper (thiodiazole-copper), chemistry are entitled：2- amino -5- sulfydryls -1,3,4- thiadiazoles copper, molecule
Formula C4H4N6S4Cu is organic copper class wide-spectrum bactericide, has both the multiple actions such as interior suction, conduction, prevention, protection, treatment, and control
The effect for the treatment of effect is more than protective effect, is efficient, low toxicity of new generation, the wide-spectrum bactericide for preventing bacterial diseases of crops,
There is preferable control effect to various bacillary and fungal disease, can be widely used for more than 20 kind 60 various bacterias of crop and true
The prevention of fungal disease；In addition Thiodiazole-copper promotes growth and development of plants supplemented with trace copper, maintains photosynthesis,
Improve cold-resistant, the drought-resistant ability of crop.
Root soil-borne disease is currently to be very difficult to the plant disease of prevention.Root soil-borne disease, complicated and changeable, mushroom is numerous
More, bacterium and fungal disease are concurrent, fold hair, and many single doses are prevented, and effect is all not satisfactory.To sum up, providing one kind can be with thiophene
Bacterium copper compounds, and the bactericidal composition that a medicine is controlled more is that the wound of the present invention grinds motivation.And have no at present Thiodiazole-copper and other medicaments into
Document report of the row compounding for preventing root soil-borne disease.
Invention content
It is an object of the invention to overcome the deficiencies of the prior art and provide one kind to be controlled a medicine more, reduces the amount of sowing, drop
The bactericidal composition and its fungicide containing Thiodiazole-copper and shenqinmycin of low cost.The compound disinfectant of the present invention can be saved
Peasant household's spray date reduces labor intensity, can prevent bacteriosis and fungal disease simultaneously, and it is unclear thin to solve peasant household's resolution
The application technology problem of fungus diseases and fungal disease.
Bactericidal composition provided by the invention containing Thiodiazole-copper and shenqinmycin, technical solution are：
The active constituent of a kind of bactericidal composition containing Thiodiazole-copper and shenqinmycin, the bactericidal composition is Thiodiazole-copper
And shenqinmycin.
Preferably, the quality proportioning of the Thiodiazole-copper and the shenqinmycin is 1~50: 1~50.
Preferably, the quality proportioning of the Thiodiazole-copper and the shenqinmycin is 20~50: 1~10.
The present invention also provides a kind of fungicide containing Thiodiazole-copper and shenqinmycin, including above-mentioned one kind containing thiophene bacterium
The bactericidal composition of copper and shenqinmycin, the fungicide contain the bactericidal composition more than 0.1% by weight.
Preferably, the fungicide is by weight containing 1%~90% bactericidal composition.
Preferably, the fungicide is by weight containing 21%~60% bactericidal composition.
Preferably, the dosage form of the fungicide is water dispersible granules, and the water dispersible granules include following mass percent
Component：21~60% bactericidal composition, 2%~7% wetting agent, 2%~7% dispersant, 2%~28% disintegration
Agent, 0.8%~4.5% antifoaming agent, 0.8%~4.5% plant growth regulator, 0.8%~2.8% synergist, 0.5
~5% bonding agent, filler are mended to 100%；
The preparation method of the water dispersible granules includes the following steps：
Step 1: preparing female powder：By 20%~50% Thiodiazole-copper, 1%~10% shenqinmycin, 2%~7% profit
Humectant, 2%~7% dispersant, 2%~28% disintegrant, 0.8%~4.5% antifoaming agent, 0.8%~4.5% plant
Object growth regulator, 0.8%~2.8% synergist, filler are mended to 95%~99.5%, be put into mixing screw stir it is mixed
16~19min is closed, the rotating speed of grader and batcher is adjusted, airslide disintegrating mill is then turned on and carries out air-flow crushing, after crushing
Material enters Agravicmixer, mixes 21~28min again, and grain size discharging after 10 microns or less, spare after testing；
Step 2: preparing adhesive solution：A certain amount of water is put into mixing screw and is heated to 71~89 DEG C, so
0.5%~5% bonding agent is added afterwards, stirs at least 1 hour, places spare；
Step 3: the preparation of product：Gained female powder and adhesive solution are uniformly mixed, then granulating and forming, are dried, it will
Shot-like particle after drying sieved, is discharged, is put in storage after analytical control qualification, packing to get to water dispersible granules.Above-mentioned moisture
The auxiliary material of shot agent can select following component：
Synergist includes one kind in organosilicon, loose ester group vegetable oil or palm kernel fatty acid methyl esters；
Filler includes that high clay, organobentonite, clay, diatomite, white carbon or precipitated calcium carbonate are one such；
Wetting agent includes azone, fatty alcohol polyoxyethylene ether, ethylene ether sulfate, alkyl phenol polyoxyethylene ether formaldehyde condensation
One kind in object sulfate, alkylnaphthalene sulfonate or bay alcohol radical sodium sulphate；
Dispersant includes ethoxylated dodecyl alcohol sodium sulphate, alkyl polyoxyethylene ether sulfonate, di-2-ethylhexylphosphine oxide naphthalene sulfonic acids
One kind in sodium or polycarboxylate；
Disintegrant includes one kind in sodium chloride, ammonium sulfate, sodium sulphate or soluble starch；
Plant growth regulator includes one kind in diethyl aminoethyl hexanoate, forchlorfenuron, compound sodium nitrophenolate, brassin or triacontanol.
Binder includes polyvinyl alcohol, soluble starch, dextrin, xanthans or carboxymethyl cellulose therein at least one
Kind；
Antifoaming agent includes organic silicon defoamer and/or polyether antifoam agent.
Organosilicon includes Silwet L-77, Silwet L-722, Silwet L-7001, Silwet L-7087, Silwet
L-7002、Silwet L-7200、Silwet L-7220、Silwet L-7602、Silwet L-7607、Silwet L-7608、
At least one of Silwet L-7657,309 Sylgard, Silwet 408 or Silwet 806.
Alternatively, the dosage form of the fungicide is suspending agent, the suspending agent includes the following components'mass percentage：21~
60% bactericidal composition, 0.1%~3.0% plant growth regulator, 2%~7% wetting agent, 2%~7% dispersion
Agent, 1.5%~4.5% thickener, 2%~7% antifreezing agent, 1.5%~4.5% organosilicon synergist, deionized water
It mends to 100%.
Preferably, the preparation method of the suspending agent includes the following steps：
Raw material is weighed by following mass percent：20%~50% Thiodiazole-copper, 1%~10% shenqinmycin, 0.1%
~3.0% plant growth regulator, 2%~7% wetting agent, 2%~7% dispersant, 1.5%~4.5% thickening
Agent, 2%~7% antifreezing agent, 1.5%~4.5% organosilicon synergist, deionized water are mended to 100%.
Above-mentioned raw materials are sanded 11-145 minutes in sand mill, be filtered to remove after sanding media obtain containing Thiodiazole-copper and
Shenqinmycin suspending agent；
Or by the raw material put into high shear homogeneous emulsifying machine high speed shear 10-50 minute after again carry out sand milling or
High-pressure homogeneous operation is obtained containing Thiodiazole-copper and shenqinmycin suspending agent.The auxiliary material of above-mentioned suspending agent can select following component：
Plant growth regulator include forchlorfenuron, diethyl aminoethyl hexanoate including compound sodium nitrophenolate, 6- benzylaminopurines, brassin,
One or more of triacontanol, gibberellin and ethephon (CEPHA),2-(chloroethyl) phosphonic acid, methyl α-naphthyl acetate or paclobutrazol.
Wetting agent include azone, EO/PO block polyethers, fatty alcohol polyoxyethylene ether, fatty alcohol polyoxyethylene ether sulfate,
APES formaldehyde condensation products sulfat, fat alcohol ethoxyl compound, tallow ethyoxyl amine salt, alkylnaphthalene sulphur
At least one of hydrochlorate, acyl glutamate, spaonin powder, penetrant t, bay alcohol radical sodium sulphate.
Dispersant includes APES formaldehyde condensation products sulfat, naphthalene sulfonic acid condensate sodium salt, phenolsulfonic acid
Condensation product sodium salt, methyl naphthalene sulfonate formaldehyde condensate, sodium lignin sulfonate, sodium metnylene bis-naphthalene sulfonate, acrylate homopolymer
At least one of sodium salt, polymeric polycarboxylic acid salt, dioctyl sodium sulphosuccinate salt, maleic acid-acrylic acid copolymer sodium salt.
Thickener includes xanthans, Arabic gum, aluminum magnesium silicate, sodium alginate, sodium carboxymethylcellulose, starch phosphate
At least one of sodium, starch Sodium Octenyl Succinate, polyvinyl alcohol, polyacrylic acid, polyvinylpyrrolidone.
Antifreezing agent includes methanol, ethyl alcohol, ethylene glycol, propylene glycol, glycerine, isopropanol, diethylene glycol (DEG), butyl glycol ether, third
At least one of glycol butyl ether.
Organosilicon synergist include Silwet L-77, Silwet L-722, Silwet L-7001, Silwet L-7087,
Silwet L-7002、Silwet L-7200、Silwet L-7220、Silwet L-7602、Silwet L-7607、Silwet
L-7608, Silwet L-7657, Sylgard309, Silwet408, Silwet806, times easily profit EW-211,
Fairland2408、Fairland2618、Fairland1100、FairlandP60、FairlandP50、Fairland2806、
At least one of B-204.
Preferably, the fungicide is for preventing in droop, samping off, root rot, blight dis-ease, seedling blight extremely
A kind of few crop disease.
Preferably, the application method of the fungicide be sprinkle in spraying, thick spray foundation position, seedling stage pour, pouring root or seed
Any one of seed dressing.
The implementation of the present invention includes following technique effect：
The present invention contains Thiodiazole-copper and the bactericidal composition of shenqinmycin can prevent and treat a variety of root soil well
Disease, such as seedling blight, samping off, watermelon blight, root rot, blight dis-ease etc. are passed, phytosis can be prevented simultaneously
Evil and fungal disease, also solve the problem that unclear bacterium and fungal disease are differentiated by peasant household；One medicine is controlled more, saves spraying time
And formulation rate, reduce labor intensity.With a variety of insecticide-applying way such as thick spray, spraying, pouring root and seed dressings.
Thiodiazole-copper belongs to chemically protective agents, main controlling object：Bacterial disease：Bacterial leaf streak of rice, water
The bacterial blight of rice, citrus ulcer, tomato bacterial leaf spot, soft rot of cabbage, angular leaf spot of cucumber etc.；Fungal disease：Mandarin orange
Tangerine shot hole, cotton in seedling stage damping-off, sigatoka, watermelon blight etc..Shenqinmycin, chemical name：Azophenlyene -1- carboxylics
Acid, molecular formula C13H8N202 are a kind of antibiotic secreted through biological culture by pseudomonas fluorescens M18, while having wide spectrum
Inhibit phytopathogen and promote the fungicide of the dual function of Effects on Plant Growth, has the characteristics that wide spectrum, efficient, it can be effective
Droop, blight dis-ease on the crops such as prevention rice, wheat, vegetables, epidemic disease, banded sclerotial blight, false smut, rice blast, downy mildew, item
Rust, sclerotiniose, head blight, anthracnose, gray mold, scab, leaf spot, bacterial wilt, canker, ginger plague and soil-borne disease.
The bactericidal composition of the present invention uses the thinking of chemical prevention+biological control, and verifies thiophene bacterium by test of many times
Copper+shenqinmycin bactericidal composition can be superimposed synergy, promote mutually, play the advantage of the two well, have synergy
Effect；It being capable of a variety of root soil-borne diseases of integrated control.
Composition of the present invention has following advantage compared with existing fungicide：
(1) two kinds of active components compounding shows excellent synergistic effect, the sterilization of mixed composition in composition
Effect is significantly improved compared with its single dose, treatment plus protective effect, and bactericidal effect is good；
(2) dosage is reduced, drug cost is reduced；
(3) reasonably mixture is carried out using the fungicide of the thinking of chemical prevention+biological control, the different mechanism of action,
Be conducive to delay the generation of drug resistance, while can achieve the effect that a medicine is controlled more, it is not only time saving and energy saving but also environmentally friendly, meet
The security requirement of pesticidal preparations.
Specific implementation mode
The present invention is described in detail below in conjunction with embodiment, it should be pointed out that described embodiment only purport
Convenient for the understanding of the present invention, and any restriction effect is not played to it.
One, Assays Example
The Toxicity Determination of embodiment 1, Thiodiazole-copper and shenqinmycin compounding to tomato wilt
Subjects：Tomato wilt bacterium (Fusarium oxysporum)
Test method：With reference to《People's Republic of China (PRC) agricultural industry criteria NY/T 1156.2-2006》Mycelial growth rate
Method.Each medicament is set 5 dosage processing by active constituent content respectively, by above-mentioned each pathogen PDA culture medium culture, waits for bacterium
It falls just when covering with culture dish, breaks into fungus block in colony edge with the card punch of diameter 5mm, fungus block is moved to transfer needle and is matched in advance
Manufactured toxic PDA culture medium center, is subsequently placed in culture in 25 DEG C of incubators, per treatment to be repeated 4 times.It is grown depending on CK bacterium colonies
Situation measures each processing colony diameter (cm) using crossing method slide calliper rule, finds out correction and inhibit percentage.Pass through inhibiting rate
Probit value and the logarithm of series concentration between linear regression analysis, find out the EC of each medicament50Value, further according to Sun Yunpei's Method
Calculate co-toxicity coefficient (CTC).
Drug effect calculates：Two diameters are surveyed in each bacterium colony right-angled intersection, and bacterium colony size is represented with its average.It finds out as the following formula
Bacterium colony growth inhibition ratio：Bacterium colony growth inhibition ratio %=(blank control bacterium colony increases diameter-chemicals treatment bacterium colony and increases diameter)
× 100/ blank control bacterium colony increases diameter.
Data analysis statistical is carried out to result, finds out regression straight line, EC50, related coefficient.According to Sun Yunpei (Y-P Sun) method
The EC50 managed everywhere in measurement is converted into practical poison exponent (ATI)；According to the mixture ratio, theoretical toxicity index is obtained
(TTI), the co-toxicity coefficient (CTC) of mixture is calculated according to the following formula.
The toxicity index of content (the %)+B of toxicity index × A of mixed toxicity index (the TTI)=A of theory in mixed ×
Contents (%) of the B in mixed
If co-toxicity coefficient is more than 120, show there is synergistic effect；If being significantly lower than 100, it is shown to be antagonism；100~
Between 120, it is shown to be summation action.
The The Toxicity Determination result of table 1, Thiodiazole-copper and shenqinmycin compounding to tomato wilt
| Reagent composition matches | EC50(μg/mL) | ATI | TTI | CTC |
| Thiodiazole-copper | 34.61 | 100.00 | / | / |
| Shenqinmycin | 13.24 | 261.40 | / | / |
| Thiodiazole-copper: shenqinmycin=50: 1 | 18.12 | 191.00 | 103.16 | 185.15 |
| Thiodiazole-copper: shenqinmycin=40: 1 | 16.89 | 204.91 | 103.94 | 197.15 |
| Thiodiazole-copper: shenqinmycin=30: 1 | 15.21 | 227.55 | 105.21 | 216.29 |
| Thiodiazole-copper: shenqinmycin=20: 1 | 13.02 | 265.82 | 107.69 | 246.85 |
| Thiodiazole-copper: shenqinmycin=10: 1 | 11.22 | 308.47 | 114.67 | 269.00 |
| Thiodiazole-copper: shenqinmycin=5: 1 | 10.69 | 323.76 | 126.90 | 255.13 |
| Thiodiazole-copper: shenqinmycin=2: 1 | 12.66 | 273.38 | 153.80 | 177.75 |
| Thiodiazole-copper: shenqinmycin=1: 1 | 10.92 | 316.94 | 180.70 | 175.40 |
| Thiodiazole-copper: shenqinmycin=1: 30 | 7.88 | 439.21 | 256.19 | 171.44 |
| Thiodiazole-copper: shenqinmycin=1: 50 | 8.09 | 427.81 | 258.24 | 165.67 |
The Toxicity Determination of embodiment 2, Thiodiazole-copper and shenqinmycin compounding to Strawberry Root Rot
Subjects：Pestalotiopsis photiniae (Pythium sp).Test method and drug effect calculate reference implementation example 1.
The The Toxicity Determination result of table 2, Thiodiazole-copper and shenqinmycin compounding to Strawberry Root Rot
| Reagent composition matches | EC50(μg/mL) | ATI | TTI | CTC |
| Thiodiazole-copper | 45.74 | 100.00 | / | / |
| Shenqinmycin | 36.78 | 124.36 | / | / |
| Thiodiazole-copper: shenqinmycin=50: 1 | 30.26 | 151.16 | 100.48 | 150.44 |
| Thiodiazole-copper: shenqinmycin=40: 1 | 29.11 | 157.13 | 100.59 | 156.20 |
| Thiodiazole-copper: shenqinmycin=30: 1 | 25.38 | 180.22 | 100.79 | 178.82 |
| Thiodiazole-copper: shenqinmycin=20: 1 | 21.36 | 214.14 | 101.16 | 211.68 |
| Thiodiazole-copper: shenqinmycin=10: 1 | 19.87 | 230.20 | 102.21 | 225.21 |
| Thiodiazole-copper: shenqinmycin=5: 1 | 18.27 | 250.36 | 104.06 | 240.59 |
| Thiodiazole-copper: shenqinmycin=2: 1 | 20.33 | 224.99 | 108.12 | 208.09 |
| Thiodiazole-copper: shenqinmycin=1: 1 | 23.04 | 198.52 | 112.18 | 176.97 |
| Thiodiazole-copper: shenqinmycin=1: 30 | 21.68 | 210.98 | 123.57 | 170.73 |
| Thiodiazole-copper: shenqinmycin=1: 50 | 22.03 | 207.63 | 123.88 | 167.60 |
The Toxicity Determination of embodiment 3, Thiodiazole-copper and shenqinmycin compounding to cucumber blight dis-ease
Subjects：Cucumber blight dis-ease germ (Mycosphaerella melonis).Test method and drug effect calculate ginseng
Examine embodiment 1.
The The Toxicity Determination result of table 3, Thiodiazole-copper and shenqinmycin compounding to cucumber blight dis-ease
The Toxicity Determination of embodiment 4, Thiodiazole-copper and shenqinmycin compounding to cotton seedling blight
Subjects：Cotton rhizoctonia solani (Rhizoctonia solani).Test method and drug effect calculate reference implementation
Example 1.
The The Toxicity Determination result of table 4, Thiodiazole-copper and shenqinmycin compounding to cotton seedling blight
| Reagent composition matches | EC50(μg/mL) | ATI | TTI | CTC |
| Thiodiazole-copper | 34.63 | 100.00 | / | / |
| Shenqinmycin | 15.36 | 225.46 | / | / |
| Thiodiazole-copper: shenqinmycin=50: 1 | 21.7 | 159.59 | 102.46 | 155.75 |
| Thiodiazole-copper: shenqinmycin=40: 1 | 17.23 | 200.99 | 103.06 | 195.02 |
| Thiodiazole-copper: shenqinmycin=30: 1 | 15.89 | 217.94 | 104.05 | 209.46 |
| Thiodiazole-copper: shenqinmycin=20: 1 | 12.56 | 275.72 | 105.97 | 260.17 |
| Thiodiazole-copper: shenqinmycin=10: 1 | 9.99 | 346.65 | 111.41 | 311.16 |
| Thiodiazole-copper: shenqinmycin=5: 1 | 10.51 | 329.50 | 120.91 | 272.51 |
| Thiodiazole-copper: shenqinmycin=2: 1 | 13.72 | 252.41 | 141.82 | 177.98 |
| Thiodiazole-copper: shenqinmycin=1: 1 | 12.33 | 280.86 | 162.73 | 172.59 |
| Thiodiazole-copper: shenqinmycin=1: 30 | 9.58 | 361.48 | 221.41 | 163.26 |
| Thiodiazole-copper: shenqinmycin=1: 50 | 9.87 | 350.86 | 223.00 | 157.34 |
Embodiment 5, Thiodiazole-copper and shenqinmycin compounding measure the toxicity of capsicum samping off
Subjects：To capsicum samping off germ (Pythium aphanidermatum).Test method and drug effect calculate
Reference implementation example 1.
The The Toxicity Determination result of table 5, Thiodiazole-copper and shenqinmycin compounding to capsicum samping off
Embodiment 6, Thiodiazole-copper and shenqinmycin compounding measure the toxicity of rice seedling blight
Subjects：Rice seedling blight germ (Rhizoctonia solani).Test method and drug effect are calculated with reference to real
Apply example 1.
The The Toxicity Determination result of table 6, Thiodiazole-copper and shenqinmycin compounding to rice seedling blight
| Reagent composition matches | EC50(μg/mL) | ATI | TTI | CTC |
| Thiodiazole-copper | 30.25 | 100.00 | / | / |
| Shenqinmycin | 13.69 | 220.96 | / | / |
| Thiodiazole-copper: shenqinmycin=50: 1 | 18.17 | 166.48 | 102.37 | 162.63 |
| Thiodiazole-copper: shenqinmycin=40: 1 | 17.03 | 177.63 | 102.95 | 172.54 |
| Thiodiazole-copper: shenqinmycin=30: 1 | 15.44 | 195.92 | 103.90 | 188.56 |
| Thiodiazole-copper: shenqinmycin=20: 1 | 12.11 | 249.79 | 105.76 | 236.19 |
| Thiodiazole-copper: shenqinmycin=10: 1 | 10.06 | 300.70 | 111.00 | 270.91 |
| Thiodiazole-copper: shenqinmycin=5: 1 | 10.24 | 295.41 | 120.16 | 245.85 |
| Thiodiazole-copper: shenqinmycin=2: 1 | 12.44 | 243.17 | 140.32 | 173.29 |
| Thiodiazole-copper: shenqinmycin=1: 1 | 11.22 | 269.61 | 160.48 | 168.00 |
| Thiodiazole-copper: shenqinmycin=1: 30 | 8.85 | 341.81 | 217.06 | 157.47 |
| Thiodiazole-copper: shenqinmycin=1: 50 | 8.98 | 336.86 | 218.59 | 154.11 |
By the data of Assays Example 1-6 it is found that Thiodiazole-copper and shenqinmycin proportioning are right between 1~50: 1~50
Damping-off, samping off, droop, root rot, blight dis-ease synergistic function are apparent, and its activity and bactericidal effect are not each groups
Divide active simple superposition, but has significant synergistic function.Thiodiazole-copper is matched with shenqinmycin 20~50: 1~10
Between effect it is more excellent.
Although reactive compound Thiodiazole-copper and shenqinmycin are known compound in the present invention, by above-mentioned activity
Compound compounding is then non-aobvious and easy for those skilled in the art to realize the desired more excellent bactericidal effect of the present invention
See.Known Fungicidal active compound enormous amount, on a small quantity can be with thiophene bacterium in order to be found in the reactive compound of magnanimity
Copper compounds and can reach the component of cooperative synergism effect, and applicant has paid a large amount of creative work, by life many times
Object is test and the test of pesticide effectiveness.
Two, preparation prepares embodiment
Embodiment 7
The preparation method of 51% water dispersible granules containing Thiodiazole-copper and shenqinmycin
Step 1: preparing female powder：By 50% Thiodiazole-copper, 1% shenqinmycin, 2%~7% azone, 2%~7%
Sodium methylene bis-naphthalene sulfonate or polycarboxylate, 2%~28% sodium chloride, 0.8%~4.5% polyether antifoam agent, 0.8%
~4.5% diethyl aminoethyl hexanoate, 0.8%~2.8% palm kernel fatty acid methyl esters, filler are mended to 95%~99.5%, and spiral shell is put into
It is stirred 16~19min in rotation mixing machine, the rotating speed of grader and batcher is adjusted, is then turned on airslide disintegrating mill into promoting the circulation of qi
Stream crushes, and the material after crushing enters Agravicmixer, mixes 21~28min again, grain size is at 10 microns or less after testing
After discharge, it is spare；
Step 2: preparing adhesive solution：A certain amount of water is put into mixing screw and is heated to 71~89 DEG C, so
0.5~5% polyvinyl alcohol is added afterwards, stirs at least 1 hour, places spare；
Step 3: the preparation of product：Gained female powder and adhesive solution are uniformly mixed, then granulating and forming, are dried, it will
Shot-like particle after drying sieved, is discharged, is put in storage after analytical control qualification, packing to get to water dispersible granules.
Embodiment 8
The preparation method of 31% water dispersible granules containing Thiodiazole-copper and shenqinmycin
Step 1: preparing female powder：By 30% Thiodiazole-copper, 1% shenqinmycin, 2%~7% aliphatic alcohol polyethenoxy
Ether, 2%~7% sodium methylene bis-naphthalene sulfonate or polycarboxylate, 2%~28% ammonium sulfate, 0.8%~4.5% polyethers
Antifoaming agent, 0.8%~4.5% triacontanol, filler are mended to 95%~99.5%, are put into mixing screw and are stirred 16
~19min adjusts the rotating speed of grader and batcher, is then turned on airslide disintegrating mill and carries out air-flow crushing, the material after crushing
Into Agravicmixer, 21~28min is mixed again, and grain size discharging after 10 microns or less, spare after testing；
Step 2: preparing adhesive solution：A certain amount of water is put into mixing screw and is heated to 71~89 DEG C, so
0.5~5% soluble starch is added afterwards, stirs at least 1 hour, places spare；
Step 3: the preparation of product：Gained female powder and adhesive solution are uniformly mixed, then granulating and forming, are dried, it will
Shot-like particle after drying sieved, is discharged, is put in storage after analytical control qualification, packing to get to water dispersible granules.
Embodiment 9
The preparation method of 22% water dispersible granules containing Thiodiazole-copper and shenqinmycin
Step 1: preparing female powder：By 20% Thiodiazole-copper, 2% shenqinmycin, 2%~7% ethylene ether sulfate,
2%~7% alkyl polyoxyethylene ether sulfonate, 2%~28% sodium sulphate, 0.8%~4.5% organic silicon defoamer,
0.8%~2.8% Silwet L-77, filler are mended to 95%~99.5%, be put into mixing screw and be stirred 16~
19min adjusts the rotating speed of grader and batcher, is then turned on airslide disintegrating mill and carries out air-flow crushing, material after crushing into
Enter Agravicmixer, mix 21~28min again, grain size discharging after 10 microns or less, spare after testing；
Step 2: preparing adhesive solution：A certain amount of water is put into mixing screw and is heated to 71~89 DEG C, so
0.5~5% dextrin is added afterwards, stirs at least 1 hour, places spare；
Step 3: the preparation of product：Gained female powder and adhesive solution are uniformly mixed, then granulating and forming, are dried, it will
Shot-like particle after drying sieved, is discharged, is put in storage after analytical control qualification, packing to get to water dispersible granules.
Embodiment 10
The preparation method of 60% water dispersible granules containing Thiodiazole-copper and shenqinmycin
Step 1: preparing female powder：By 50% Thiodiazole-copper, 10% shenqinmycin, 2%~7% alkyl phenol polyoxy second
Alkene ether formaldehyde condensation products sulfate, 2%~7% alkyl polyoxyethylene ether sulfonate, 2%~28% sodium sulphate, 0.8%~
4.5% organic silicon defoamer, 0.8%~4.5% brassin, 0.8%~2.8% Silwet L-7200, filler mend to
95%~99.5%, it is put into mixing screw and is stirred 16~19min, adjust the rotating speed of grader and batcher, then
It opens airslide disintegrating mill and carries out air-flow crushing, the material after crushing enters Agravicmixer, mixes 21~28min, warp again
Grain size discharging after 10 microns or less is detected, it is spare；
Step 2: preparing adhesive solution：A certain amount of water is put into mixing screw and is heated to 71~89 DEG C, so
0.5~5% xanthans is added afterwards, stirs at least 1 hour, places spare；
Step 3: the preparation of product：Gained female powder and adhesive solution are uniformly mixed, then granulating and forming, are dried, it will
Shot-like particle after drying sieved, is discharged, is put in storage after analytical control qualification, packing to get to water dispersible granules.
Embodiment 11
The preparation method of 35% water dispersible granules containing Thiodiazole-copper and shenqinmycin
Step 1: preparing female powder：By 30% Thiodiazole-copper, 5% shenqinmycin, 2%~7% alkylnaphthalene sulfonate,
2%~7% alkyl polyoxyethylene ether sulfonate, 2%~28% soluble starch, 0.8%~4.5% organosilicon defoaming
Agent, 0.8%~4.5% compound sodium nitrophenolate, 0.8%~2.8% Silwet L-7657, filler are mended to 95%~99.5%, are put
Enter and be stirred 16~19min in mixing screw, adjust grader and batcher rotating speed, be then turned on airslide disintegrating mill into
Row air-flow crushing, the material after crushing enter Agravicmixer, mix 21~28min again, grain size is at 10 microns after testing
It discharges after below, it is spare；
Step 2: preparing adhesive solution：A certain amount of water is put into mixing screw and is heated to 71~89 DEG C, so
0.5~5% carboxymethyl cellulose is added afterwards, stirs at least 1 hour, places spare；
Step 3: the preparation of product：Gained female powder and adhesive solution are uniformly mixed, then granulating and forming, are dried, it will
Shot-like particle after drying sieved, is discharged, is put in storage after analytical control qualification, packing to get to water dispersible granules.
Embodiment 12
The preparation method of 30% water dispersible granules containing Thiodiazole-copper and shenqinmycin
Step 1: preparing female powder：By 20% Thiodiazole-copper, 10% shenqinmycin, 2%~7% bay alcohol radical sulfuric acid
Sodium, 2%~7% ethoxylated dodecyl alcohol sodium sulphate, 2%~28% soluble starch, 0.8%~4.5% it is organic
Silicon defoaming agent, 0.8%~4.5% forchlorfenuron, 0.8%~2.8% Silwet 806, filler mend to 95%~
99.5%, it is put into mixing screw and is stirred 16~19min, adjust the rotating speed of grader and batcher, be then turned on gas
It flows pulverizer and carries out air-flow crushing, the material after crushing enters Agravicmixer, mixes 20~28min again, after testing grain
Diameter discharging after 10 microns or less, it is spare；
Step 2: preparing adhesive solution：A certain amount of water is put into mixing screw and is heated to 71~89 DEG C, so
0.5~5% carboxymethyl cellulose is added afterwards, stirs at least 1 hour, places spare；
Step 3: the preparation of product：Gained female powder and adhesive solution are uniformly mixed, then granulating and forming, are dried, it will
Shot-like particle after drying sieved, is discharged, is put in storage after analytical control qualification, packing to get to water dispersible granules.
Embodiment 13
The preparation method of 0.1% water dispersible granules containing Thiodiazole-copper and shenqinmycin
Step 1: preparing female powder：By 0.06% Thiodiazole-copper, 0.04% shenqinmycin, 2%~7% alkyl phenol is poly-
Ethylene oxide ether formaldehyde condensation products sulfate, 2%~7% alkyl polyoxyethylene ether sulfonate, 2%~28% sodium sulphate,
0.8%~4.5% organic silicon defoamer, 0.8%~4.5% brassin, 0.8%~2.8% Silwet L-7200,
Filler is mended to 95%~99.5%, is put into mixing screw and is stirred 16~19min, and turn of grader and batcher is adjusted
Speed is then turned on airslide disintegrating mill and carries out air-flow crushing, and the material after crushing enters Agravicmixer, mix 21 again~
28min, grain size discharging after 10 microns or less, spare after testing；
Step 2: preparing adhesive solution：A certain amount of water is put into mixing screw and is heated to 71~89 DEG C, so
0.5~5% xanthans is added afterwards, stirs at least 1 hour, places spare；
Step 3: the preparation of product：Gained female powder and adhesive solution are uniformly mixed, then granulating and forming, are dried, it will
Shot-like particle after drying sieved, is discharged, is put in storage after analytical control qualification, packing to get to water dispersible granules.
Embodiment 14
The preparation method of 1% water dispersible granules containing Thiodiazole-copper and shenqinmycin
Step 1: preparing female powder：By 0.8% Thiodiazole-copper, 0.2% shenqinmycin, 2%~7% alkyl naphthalene sulfonic acid
Salt, 2%~7% alkyl polyoxyethylene ether sulfonate, 2%~28% soluble starch, 0.8%~4.5% organosilicon
Antifoaming agent, 0.8%~4.5% compound sodium nitrophenolate, 0.8%~2.8% Silwet L-7657, filler mend to 95%~
99.5%, it is put into mixing screw and is stirred 16~19min, adjust the rotating speed of grader and batcher, be then turned on gas
It flows pulverizer and carries out air-flow crushing, the material after crushing enters Agravicmixer, mixes 21~28min again, after testing grain
Diameter discharging after 10 microns or less, it is spare；
Step 2: preparing adhesive solution：A certain amount of water is put into mixing screw and is heated to 71~89 DEG C, so
0.5~5% carboxymethyl cellulose is added afterwards, stirs at least 1 hour, places spare；
Step 3: the preparation of product：Gained female powder and adhesive solution are uniformly mixed, then granulating and forming, are dried, it will
Shot-like particle after drying sieved, is discharged, is put in storage after analytical control qualification, packing to get to water dispersible granules.
Embodiment 15
The preparation method of 90% water dispersible granules containing Thiodiazole-copper and shenqinmycin
Step 1: preparing female powder：By 60% Thiodiazole-copper, 30% shenqinmycin, 2%~7% bay alcohol radical sulfuric acid
Sodium, 2%~7% ethoxylated dodecyl alcohol sodium sulphate, 2%~28% soluble starch, 0.8%~4.5% it is organic
Silicon defoaming agent, 0.8%~4.5% forchlorfenuron, 0.8%~2.8% Silwet 806, filler mend to 95%~
99.5%, it is put into mixing screw and is stirred 16~19min, adjust the rotating speed of grader and batcher, be then turned on gas
It flows pulverizer and carries out air-flow crushing, the material after crushing enters Agravicmixer, mixes 20~28min again, after testing grain
Diameter discharging after 10 microns or less, it is spare；
Step 2: preparing adhesive solution：A certain amount of water is put into mixing screw and is heated to 71~89 DEG C, so
0.5~5% carboxymethyl cellulose is added afterwards, stirs at least 1 hour, places spare；
Step 3: the preparation of product：Gained female powder and adhesive solution are uniformly mixed, then granulating and forming, are dried, it will
Shot-like particle after drying sieved, is discharged, is put in storage after analytical control qualification, packing to get to water dispersible granules.
Above-described embodiment 7-15 overcomes that disintegration existing for the water dispersible granules containing inorganic copper fungicide is poor, suspensibility
Low disadvantage.Above-mentioned water dispersible granules can be disintegrated rapidly after entering water, and dispersion forms higher suspension dispersion, acyclic using convenience
Traditional formulations of pesticide are polluted and have the advantages that in border, and safety is good, and added value is high, good in economic efficiency.
Embodiment 16
The preparation method of 51% suspending agent containing Thiodiazole-copper and shenqinmycin
Raw material is weighed by following mass percent：50% Thiodiazole-copper, 1% shenqinmycin, 0.1%~3.0% chlorine
Pyrrole phenylurea and diethyl aminoethyl hexanoate, 2%~7% azone, 2%~7% sodium metnylene bis-naphthalene sulfonate, 1.5%~4.5% xanthan
Glue, 2%~7% diethylene glycol (DEG), 1.5%~4.5% Silwet L-77, deionized water are mended to 100%.
Above-mentioned raw materials are sanded 12-144 minutes in sand mill, be filtered to remove after sanding media obtain containing Thiodiazole-copper and
Shenqinmycin suspending agent；
Or raw material is put into after high shear homogeneous emulsifying machine high speed is sheared 10-50 minutes and carries out sand milling or high pressure again
Homogeneous operates, and obtains containing Thiodiazole-copper and shenqinmycin suspending agent.
Embodiment 17
The preparation method of 31% suspending agent containing Thiodiazole-copper and shenqinmycin
Raw material is weighed by following mass percent：30% Thiodiazole-copper, 1% shenqinmycin, 0.1%~3.0% answers
Nitre phenol sodium and 6- benzylaminopurines, 2%~7% EO/PO block polyethers, 2%~7% sodium lignin sulfonate, 1.5%~
4.5% Arabic gum, 2%~7% isopropanol, 1.5%~4.5% Silwet L-722, deionized water mend to
100%.
Above-mentioned raw materials are sanded 12-144 minutes in sand mill, be filtered to remove after sanding media obtain containing Thiodiazole-copper and
Shenqinmycin suspending agent；
Or raw material is put into after high shear homogeneous emulsifying machine high speed is sheared 10-50 minutes and carries out sand milling or high pressure again
Homogeneous operates, and obtains containing Thiodiazole-copper and shenqinmycin suspending agent.
Embodiment 18
The preparation method of 22% suspending agent containing Thiodiazole-copper and shenqinmycin
Raw material is weighed by following mass percent：20% Thiodiazole-copper, 2% shenqinmycin, 0.1%~3.0% rue
Tongue element and ethephon (CEPHA),2-(chloroethyl) phosphonic acid, 2%~7% fatty alcohol polyoxyethylene ether, 2%~7% methyl naphthalene sulfonate formaldehyde condensate,
1.5%~4.5% aluminum magnesium silicate, 2%~7% glycerine, 1.5%~4.5% Silwet L-7220, deionized water
It mends to 100%.
Above-mentioned raw materials are sanded 12-144 minutes in sand mill, be filtered to remove after sanding media obtain containing Thiodiazole-copper and
Shenqinmycin suspending agent；
Or raw material is put into after high shear homogeneous emulsifying machine high speed is sheared 10-50 minutes and carries out sand milling or high pressure again
Homogeneous operates, and obtains containing Thiodiazole-copper and shenqinmycin suspending agent.
Embodiment 19
The preparation method of 60% suspending agent containing Thiodiazole-copper and shenqinmycin
Raw material is weighed by following mass percent：50% Thiodiazole-copper, 10% shenqinmycin, 0.1%~3.0% it is red
Mycin and triacontanol, 2%~7% fatty alcohol polyoxyethylene ether sulfate, 2%~7% phenolsulfonic acid condensation product sodium salt,
1.5%~4.5% sodium alginate, 2%~7% propylene glycol, 1.5%~4.5% Sylgard309, deionized water mend to
100%.
Above-mentioned raw materials are sanded 12-144 minutes in sand mill, be filtered to remove after sanding media obtain containing Thiodiazole-copper and
Shenqinmycin suspending agent；
Or raw material is put into after high shear homogeneous emulsifying machine high speed is sheared 10-50 minutes and carries out sand milling or high pressure again
Homogeneous operates, and obtains containing Thiodiazole-copper and shenqinmycin suspending agent.
Embodiment 20
The preparation method of 35% suspending agent containing Thiodiazole-copper and shenqinmycin
Raw material is weighed by following mass percent：30% Thiodiazole-copper, 5% shenqinmycin, 2%~7% alkyl phenol
Polyoxyethylene ether formaldehyde condensation products sulfate, 2%~7% naphthalene sulfonic acid condensate sodium salt, 1.5%~4.5% carboxymethyl are fine
The plain sodium of dimension, 2%~7% ethyl alcohol, 1.5%~4.5% times easily profit EW-211, a deionized water are mended to 100%.
Above-mentioned raw materials are sanded 12-144 minutes in sand mill, be filtered to remove after sanding media obtain containing Thiodiazole-copper and
Shenqinmycin suspending agent；
Or raw material is put into after high shear homogeneous emulsifying machine high speed is sheared 10-50 minutes and carries out sand milling or high pressure again
Homogeneous operates, and obtains containing Thiodiazole-copper and shenqinmycin suspending agent.
Embodiment 21
The preparation method of 30% suspending agent containing Thiodiazole-copper and shenqinmycin
Raw material is weighed by following mass percent：20% Thiodiazole-copper, 10% shenqinmycin, the three of 0.1%~3.0%
Ten alkanols and gibberellin, 2%~7% fat alcohol ethoxyl compound, 2%~7% alkyl phenol polyoxyethylene ether formaldehyde contracting
Close object sulfate, 1.5%~4.5% starch phosphate sodium, 2%~7% methanol, 1.5%~4.5% B-204, go from
Sub- water is mended to 100%.
Above-mentioned raw materials are sanded 12-144 minutes in sand mill, be filtered to remove after sanding media obtain containing Thiodiazole-copper and
Shenqinmycin suspending agent；
Or raw material is put into after high shear homogeneous emulsifying machine high speed is sheared 10-50 minutes and carries out sand milling or high pressure again
Homogeneous operates, and obtains containing Thiodiazole-copper and shenqinmycin suspending agent.
Embodiment 22
The preparation method of 30% suspending agent containing Thiodiazole-copper and shenqinmycin
Raw material is weighed by following mass percent：15% Thiodiazole-copper, 15% shenqinmycin, 0.1%~3.0% rue
Tongue element and ethephon (CEPHA),2-(chloroethyl) phosphonic acid, 2%~7% fatty alcohol polyoxyethylene ether, 2%~7% methyl naphthalene sulfonate formaldehyde condensate,
1.5%~4.5% aluminum magnesium silicate, 2%~7% glycerine, 1.5%~4.5% Silwet L-7220, deionized water
It mends to 100%.
Above-mentioned raw materials are sanded 12-144 minutes in sand mill, be filtered to remove after sanding media obtain containing Thiodiazole-copper and
Shenqinmycin suspending agent；
Or raw material is put into after high shear homogeneous emulsifying machine high speed is sheared 10-50 minutes and carries out sand milling or high pressure again
Homogeneous operates, and obtains containing Thiodiazole-copper and shenqinmycin suspending agent.
Embodiment 23
The preparation method of 31% suspending agent containing Thiodiazole-copper and shenqinmycin
Raw material is weighed by following mass percent：1% Thiodiazole-copper, 30% shenqinmycin, 0.1%~3.0% it is red
Mycin and triacontanol, 2%~7% fatty alcohol polyoxyethylene ether sulfate, 2%~7% phenolsulfonic acid condensation product sodium salt,
1.5%~4.5% sodium alginate, 2%~7% propylene glycol, 1.5%~4.5% Sylgard309, deionized water mend to
100%.
Above-mentioned raw materials are sanded 12-144 minutes in sand mill, be filtered to remove after sanding media obtain containing Thiodiazole-copper and
Shenqinmycin suspending agent；
Or raw material is put into after high shear homogeneous emulsifying machine high speed is sheared 10-50 minutes and carries out sand milling or high pressure again
Homogeneous operates, and obtains containing Thiodiazole-copper and shenqinmycin suspending agent.
Embodiment 24
The preparation method of 80% suspending agent containing Thiodiazole-copper and shenqinmycin
Raw material is weighed by following mass percent：10% Thiodiazole-copper, 70% shenqinmycin, 0.1%~3.0% naphthalene
Acetic acid and paclobutrazol, 2%~7% APES formaldehyde condensation products sulfat, 2%~7% naphthalene-sulfonic acid condensation
Object sodium salt, 1.5%~4.5% sodium carboxymethylcellulose, 2%~7% ethyl alcohol, deionized water are mended to 100%.
Above-mentioned raw materials are sanded 12-144 minutes in sand mill, be filtered to remove after sanding media obtain containing Thiodiazole-copper and
Shenqinmycin suspending agent；
Or raw material is put into after high shear homogeneous emulsifying machine high speed is sheared 10-50 minutes and carries out sand milling or high pressure again
Homogeneous operates, and obtains containing Thiodiazole-copper and shenqinmycin suspending agent.
Embodiment 25
The preparation method of 51% suspending agent containing Thiodiazole-copper and shenqinmycin
Raw material is weighed by following mass percent：1% Thiodiazole-copper, 50% shenqinmycin, the three of 0.1%~3.0%
Ten alkanols and gibberellin, 2%~7% fat alcohol ethoxyl compound, 2%~7% alkyl phenol polyoxyethylene ether formaldehyde contracting
Close object sulfate, 1.5%~4.5% starch phosphate sodium, 2%~7% methanol, 1.5%~4.5% B-204, go from
Sub- water is mended to 100%.
Above-mentioned raw materials are sanded 12-144 minutes in sand mill, be filtered to remove after sanding media obtain containing Thiodiazole-copper and
Shenqinmycin suspending agent；
Or raw material is put into after high shear homogeneous emulsifying machine high speed is sheared 10-50 minutes and carries out sand milling or high pressure again
Homogeneous operates, and obtains containing Thiodiazole-copper and shenqinmycin suspending agent.
The active constituent of the bactericidal composition of embodiment 7-25 is Thiodiazole-copper and shenqinmycin, the Thiodiazole-copper and the Shen
The quality proportioning of piperazine mycin is 1~50: 1~50.Preferably, the quality proportioning of the Thiodiazole-copper and the shenqinmycin be 20~
50: 1~10.Fungicide contains the bactericidal composition more than 0.1% by weight.Preferably, the fungicide is with weight
Meter contains 1~90% bactericidal composition.It is further preferred that the fungicide is by weight containing 21~60% institute
State bactericidal composition.
Three, the Field information test of pesticide effectiveness
Embodiment 26
The present embodiment selects the water dispersible granules that above-described embodiment 7-25 obtains and suspending agent to carry out the test of pesticide effectiveness, comparison medicine
Agent uses 1% shenqinmycin SC and 20% Thiodiazole-copper SC.
Watermelon blight field control effectiveness test is prevented with reference to medicine inspecting institute of the Ministry of Agriculture " pesticide field efficacy medicine test criterion (two)
GB/T17980.113-2004 bactericidal agent for preventing and treating cucurbits fusarium wilt " carries out field control effectiveness test.Test medicine, comparison medicament and sky
The cell processing compareed in vain is arranged using random district's groups, plot area 25m2, 4 repetitions, pouring root.Investigate all plant in cell
Whether the classical symptom of droop, record droop morbidity strain number and investigation total strain number are had.
Diseased plant rate %=diseased plant numbers/investigation total strain number × 100
Control effect %=(blank district diseased plant rate-treatment region diseased plant rate) × 100/ blank district diseased plant rate
Table 7：Different dosage forms are to watermelon blight field control effectiveness test result prepared by embodiment 7-25
From 7 data result of table it is found that the present invention a kind of bactericidal composition containing Thiodiazole-copper and shenqinmycin, 20%~
50% Thiodiazole-copper and the active constituent of 1%~10% shenqinmycin compounding all have good drug effect and synergy to germ evil
Effect originally, when for preventing the roots soil-borne disease such as droop, samping off, root rot, blight dis-ease, seedling blight has higher
Control effect, after 1 medicine of dispenser 14 days after 7 days and 2 medicines, preventive effect killing under 85% or more, part conditions of mixture ratios
The preventive effect of bacteria composition can reach 90% or more, hence it is evident that be better than the preventive effect of Thiodiazole-copper single dose and shenqinmycin single dose.Therefore, this hair
A kind of bright bactericidal composition containing Thiodiazole-copper and shenqinmycin, preventive effect and production-increasing function are all higher than when two kinds of single doses use
Effect, complex preparation not only extend the lasting period, improve drug effect, and successfully manage the drug resistance of disease, while having again higher
Economic benefit.
Applicant has found have as long as the fungicide containing Thiodiazole-copper and shenqinmycin passes disease to root during the test
There is excellent preventive effect, refers to above-described embodiment.Preventive effect can be further increased added with plant growth regulator and synergist.It is above-mentioned
Synergist selected by embodiment is the compound of a kind of basic inactive, very low to higher mammal toxicity, but and pesticide
When mixed, it can play and extend the drug effect term of validity, improve bioactivity, reduce dosage, reduce cost, the work preserved the ecological environment
With.Can not only several times, decades of times improve pesticide control effect, can also delaying drug resistance generate, extend hard-won pesticide
The life cycle of kind.
The preventive effect of compounding agent is also related with the characteristic of selected synergist kind itself, be not fungicide it is effective at
Divide and the random mixture of synergist can synergy.Therefore before compounding, it is necessary to understand fully active ingredient and the physicochemical property of synergist, and
It is taken in from virulence, toxicity and preparation performance etc., under normal circumstances, by the different medicament of the mode of action, the mechanism of action
Mixture or according to the feature in the mechanism of action of fungicide Thiodiazole-copper and shenqinmycin selects corresponding synergist and is increased with generating
Effect acts on.The organosilicon synergist added in above-described embodiment can enhance liquid in the wet of plant surface or pest body surface
Moisten, stick and open up ability.The effective active composition in liquid is set to penetrate into target body gap rapidly and be opened in extended surface, it can be big
Increase the area coverage sprayed insecticide and penetration greatly, to improve drug effect.Considerably reduce the access times and dosage of pesticide.
Itself is without any side effects to people and animals, crop and environment, is readily biodegradable, not contaminated land.
In the compounding agent of above-described embodiment be added with plant growth regulator, effectively adjust improve crop growth and development,
Metabolic processes, optimize the interior ecological environment of crop, while significantly promoting absorption of the crop to Thiodiazole-copper and shenqinmycin
It utilizes, obtained bactericidal composition drug effect higher, sterilizing ability is stronger, is remained on crops lower；Plant growth regulator is same
Agriculture chemical compounding uses, and selects the different kinds and concentrations of plant growth regulator, also different for the preventive effect result of plant,
By a large amount of pilot studies, the plant growth regulator preferably gone out and its proportioning are obtained, it is unknown to avoid generation poisoning or effect
It is aobvious.
Four, Hygiene Toxicology is tested
Embodiment 27
Hygiene Toxicology experiment is carried out to the obtained water dispersible granules of embodiment 7-25 and suspending agent.
The water dispersible granules and suspending agent of measurement embodiment 7-25 are applied to the median lethal dose (LD for 24 hours of various animals50,
Mg/kg) or for 24 hours half lethal concentration (LC50, mg/L), experimental result is shown in Table 8：
Table 8：Hygiene Toxicology test result
Table 8 the result shows that, the median lethal dose for 24 hours of embodiment 7-25 or for 24 hours half lethal concentration numerical value are very big, explanation
Each fungicide is smaller to the murder by poisoning risk of animal, and safety is high, belongs to environmentally friendly less toxic fungicide.
Finally it should be noted that the above embodiments are merely illustrative of the technical solutions of the present invention, rather than the present invention is protected
The limitation of range is protected, although being explained in detail to the present invention with reference to preferred embodiment, those skilled in the art answer
Work as understanding, technical scheme of the present invention can be modified or replaced equivalently, without departing from the reality of technical solution of the present invention
Matter and range.
Claims (9)
1. a kind of bactericidal composition containing Thiodiazole-copper and shenqinmycin, it is characterised in that：The bactericidal composition activity at
It is divided into Thiodiazole-copper and shenqinmycin, the quality proportioning of the Thiodiazole-copper and the shenqinmycin is 1~50：1~50.
2. a kind of bactericidal composition containing Thiodiazole-copper and shenqinmycin according to claim 1, it is characterised in that：It is described
The quality proportioning of Thiodiazole-copper and the shenqinmycin is 20~50:1~10.
3. a kind of fungicide containing Thiodiazole-copper and shenqinmycin, it is characterised in that：Including one kind as claimed in claim 1 or 2
Bactericidal composition containing Thiodiazole-copper and shenqinmycin, the fungicide contain the sterilization group more than 0.1% by weight
Close object.
4. a kind of fungicide containing Thiodiazole-copper and shenqinmycin according to claim 3, it is characterised in that：The sterilization
Agent is by weight containing 1%~90% bactericidal composition.
5. a kind of fungicide containing Thiodiazole-copper and shenqinmycin according to claim 4, it is characterised in that：The sterilization
Agent is by weight containing 21%~60% bactericidal composition.
6. a kind of fungicide containing Thiodiazole-copper and shenqinmycin according to claim 3, it is characterised in that：The sterilization
The dosage form of agent is water dispersible granules, and the water dispersible granules include the following components'mass percentage：21%~60% sterilization
Composition, 2%~7% wetting agent, 2%~7% dispersant, 2%~28% disintegrant, 0.8%~4.5% defoaming
Agent, 0.8%~4.5% plant growth regulator, 0.8%~2.8% synergist, 0.5%~5% bonding agent, filler
It mends to 100%；
Alternatively, the dosage form of the fungicide is suspending agent, the suspending agent includes the following components'mass percentage：21%~
60% bactericidal composition, 0.1%~3.0% plant growth regulator, 2%~7% wetting agent, 2%~7% dispersion
Agent, 1.5%~4.5% thickener, 2%~7% antifreezing agent, 1.5%~4.5% organosilicon synergist, deionized water
It mends to 100%.
7. a kind of fungicide containing Thiodiazole-copper and shenqinmycin according to claim 6, it is characterised in that：The moisture
The preparation method of shot agent includes the following steps：
Step 1: preparing female powder：By 20%~50% Thiodiazole-copper, 1%~10% shenqinmycin, 2%~7% wetting
Agent, 2%~7% dispersant, 2%~28% disintegrant, 0.8%~4.5% antifoaming agent, 0.8%~4.5% plant
Growth regulator, 0.8%~2.8% synergist, filler are mended to 95%~99.5%, are put into mixing screw and are stirred
16~19min adjusts the rotating speed of grader and batcher, is then turned on airslide disintegrating mill and carries out air-flow crushing, the object after crushing
Material enters Agravicmixer, mixes 21~28min again, and grain size discharging after 10 microns or less, spare after testing；
Step 2: preparing adhesive solution：A certain amount of water is put into mixing screw and is heated to 71~89 DEG C, is then added
Enter 0.5%~5% bonding agent, stir at least 1 hour, places spare；
Step 3: the preparation of product：Gained female powder and adhesive solution are uniformly mixed, then granulating and forming, dry, will dry
Shot-like particle afterwards sieved, is discharged, is put in storage after analytical control qualification, packing to get to water dispersible granules.
8. according to a kind of any fungicide containing Thiodiazole-copper and shenqinmycin of claim 3-7, it is characterised in that：Institute
Fungicide is stated for preventing at least one of droop, samping off, root rot, blight dis-ease, seedling blight crop disease.
9. according to a kind of any fungicide containing Thiodiazole-copper and shenqinmycin of claim 3-7, it is characterised in that：Institute
The application method for stating fungicide be sprinkle in spraying, thick spray foundation position, seedling stage pour, any one of pouring root or seed seed dressing.
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