CN106214862B - A kind of Traditional Chinese veterinary medicine oral solution and preparation method thereof preventing and treating the atypical newcastle disease of chicken - Google Patents

A kind of Traditional Chinese veterinary medicine oral solution and preparation method thereof preventing and treating the atypical newcastle disease of chicken Download PDF

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CN106214862B
CN106214862B CN201610695005.XA CN201610695005A CN106214862B CN 106214862 B CN106214862 B CN 106214862B CN 201610695005 A CN201610695005 A CN 201610695005A CN 106214862 B CN106214862 B CN 106214862B
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chicken
radix
newcastle disease
traditional chinese
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CN106214862A (en
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赵增成
林树乾
宋敏训
李桂明
黄中利
冯敏燕
杨世发
傅剑
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Poultry Research Institute Shandong Academy of Agricultural Sciences
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Abstract

The invention belongs to field of traditional Chinese veterinary, particularly disclose a kind of Traditional Chinese veterinary medicine oral solution and preparation method thereof for preventing and treating the atypical newcastle disease of chicken.The Traditional Chinese veterinary medicine oral solution of the atypical newcastle disease of prevention and treatment chicken is using hairyvein agrimony, herba lysimachiae, Radix Isatidis, Radix Astragali, polygonum cuspidate, rhizome of cyrtomium, radix scutellariae, radix ampelopsis, Radix Glycyrrhizae as active constituent, it is made by certain parts by weight, dedicated for preventing and treating the chronic newcastle disease of chicken, it is significant in efficacy, can drink water medication, and poultry medication is convenient, degree of being absorbed and utilized height, drug residue free is of great significance to the green and healthy cultivation of guarantee poultry.

Description

A kind of Traditional Chinese veterinary medicine oral solution and preparation method thereof preventing and treating the atypical newcastle disease of chicken
Technical field
The invention belongs to field of traditional Chinese veterinary, in particular to a kind of Traditional Chinese veterinary medicine oral solution for preventing and treating the atypical newcastle disease of chicken and Preparation method.
Background technique
Newcastle disease (ND) is that acute, the hot, septic of one kind of the fowl as caused by newcastle disease virus and high degree in contact pass It catches an illness, illness has very high disease incidence characterized by high fever, expiratory dyspnea, diarrhea, neurological disorders, mucous membrane and serous coat bleeding And case fatality rate, it is a kind of Infectious Diseases for endangering aviculture.With the generally use of vaccine, the typical newcastle disease of high mortality Less generation, but with disease incidence 10%-30%, clinical symptoms are unobvious, pathological change is not true to type, the death rate is not high, lay eggs The non typical newcastle disease that chicken egg drop reduction is characterized then repeated, and have brought tremendous economic losses to aviculture.
Newcastle disease mainly uses vaccine immunity to be prevented, and chicken group there is no specific treatment medicine, especially exist once falling ill The antiviral Western medicine such as amantadine, Ribavirin disables after poultry in China, and the treatment of newcastle disease has become more outstanding Problem.Chinese herbal medicine is a big treasure-house of China's traditional medicine, has the characteristics that Yin Yang balancing, eliminating pathogen to support vital qi, treating both manifestation and root cause of disease, positive day Benefit becomes the hot spot of new antiviral drug research.Because Chinese medicine has, effect is unique, antiviral spectrum is wide, toxic side effect is small, significant in efficacy The advantages that, many large size livestock and poultry cultivation enterprises make herbal medicine as the emphasis for preventing, treating disease and promotion growth of animal Herbal medicine use with object, middle-size and small-size farm (family) is also increasingly extensive.With the continuous improvement of people's living standards, China Apparent variation has occurred in people's diet structure, and green products of domestic animal is favored by market deeply.It solves to raise by herbal control Western medicine residue problem in poultry product produces nontoxic, harmless animal products, becomes the inexorable trend of the following animal husbandry development. Therefore, a kind of Chinese herbal medicine non typical newcastle disease according to caused by diagnosis and treatment based on an overall analysis of the illness and the patient's condition principle prevention and treatment exogenous disease plague is needed.
Summary of the invention
Reasonable simple, each composition proportion, good effect are prepared, without medicine the technical problem to be solved in the present invention is to provide a kind of Residual, poultry is easy to absorption, the Traditional Chinese veterinary medicine oral solution of the prevention and treatment atypical newcastle disease of chicken easy to use and preparation method thereof.
The technical solution of the present invention is as follows:
It is a kind of prevent and treat the atypical newcastle disease of chicken Traditional Chinese veterinary medicine oral solution, active constituent by following parts by weight raw material Be made: 10~30 parts of hairyvein agrimony, 10~30 parts of Radix Isatidis, 7~21 parts of Radix Astragali, 10~30 parts of polygonum cuspidate, is passed through at 12~36 parts of herba lysimachiae Many 18~24 parts, 18~24 parts of radix scutellariaes, 7~21 parts of radix ampelopsis, 3~9 parts of Radix Glycyrrhizae.
The Traditional Chinese veterinary medicine oral solution of the atypical newcastle disease of prevention and treatment chicken, the weight proportion of preferred each raw material are as follows: red crowned crane It is 20 parts of grass, 24 parts of herba lysimachiae, 20 parts of Radix Isatidis, 14 parts of Radix Astragali, 20 parts of polygonum cuspidate, 21 parts of rhizome of cyrtomium, 21 parts of radix scutellariae, 14 parts of radix ampelopsis, sweet 6 parts of grass.
The preparation method of the Traditional Chinese veterinary medicine oral solution of the atypical newcastle disease of prevention and treatment chicken, using following steps:
(1) each raw material mixing for weighing above-mentioned parts by weight is placed in Chinese medicine extracting tank, is added water to cook 2 times, specific side Method are as follows: for the first time plus the water of 7 times of weight, immersion 1 hour are boiled 1 hour, and first-time filtrate is obtained after filtering；Second plus 3 times of weight Water, boil 0.5 hour, after filtering secondary filtrate；
(2) merge first-time filtrate obtained and secondary filtrate in step (1), obtain merging filtrate；Merging filtrate is depressurized dense It is reduced to every milliliter of concentrate and is equivalent to 1g crude drug, obtain concentrate；
(3) it will be added in concentrate made from step (2) and account for concentrate weight than the sodium benzoate for 0.3%, stirring is equal The even Traditional Chinese veterinary medicine oral solution to get the prevention and treatment atypical newcastle disease of chicken.
Usage and dosage: daily 1ml/kg weight, drinking-water are used in conjunction 4-5 days.
The pharmacological property and pharmacology analysis of Chinese medicine material selected by the present invention are as follows:
Polygonum cuspidate: mildly bitter flavor, cold nature.Enter liver, gallbladder, lung three to pass through.It is clearing heat and detoxicating with removing dampness through diuresis and removing jaundice, removing blood stasis and acesodyne, cough-relieving The function of resolving sputum.Cure mainly jaundice with damp-heat pathogen, stranguria with turbid discharge, leukorrhagia, rheumatic arthralgia, carbuncle sore tumefacting virus, scald, menostasis, abdominal mass, instep beats damage Wound, cough with lung heat.
Hairyvein agrimony: it is bitter, puckery, it is mild-natured.Enter the heart, liver two passes through.With astringing to arrest bleeding, detoxification sore treatment, desinsection, puckery sweat, cough-relieving Function.Cure mainly hemoptysis, spit blood, bleeding from five sense organs or subcutaneous tissue, hematuria, metrorrhagia and metrostaxis, bloody flux, malaria, diabete hidrosis, overstrain cough etc. diseases, control trichomonad outside The diseases such as property vaginitis, furuncle sore carbuncle swells, hemorrhoid.
Radix Isatidis: bitter, it is cold in nature.Enter the heart, stomach two passes through.With clearing heat and detoxicating, cool blood, the function of relieving sore-throat.Poison when curing mainly warm epidemic disease, Fever pharyngalgia, febrile virulent maculae, mumps, scarlet fever, major part pestilence, erysipelas, carbuncle swells.
Herba lysimachiae: sweet in flavor, salty, cold nature.Enter liver, gallbladder, kidney, bladder four to pass through.It is clearing heat and detoxicating with promoting diuresis for stranguria, dissipate the stasis of blood Detumescence, eliminating dampness and heat, Sha Lin, urine is puckery to have a pain, jaundice and reddish urine, the function of carbuncle swells furunculosis.Cure mainly liver and gallbladder and stone in urinary system, heat gonorrhea, Nephritic dropsy, jaundice with damp-heat pathogen, sore carbuncle swells, venomous snake bite, traumatic injury.
Radix Astragali: sweet in flavor, slightly warm in nature.Enter spleen, lung two passes through.Consolidate table, the function of torr sore myogenic with polishing.Physically weak spontaneous perspiration is cured mainly, Chronic diarrhea, rectal prolapse, uterine prolapse, chronic nephritis, physically weak edema, chronic ulcer, the long disunion of the open sore part.
Rhizome of cyrtomium: bitter, it is slightly cold.Return liver, the spleen channel.With desinsection, heat-clearing, removing toxic substances, the function of cooling blood and hemostasis.Cure mainly wind-heat sense It emits, warms ecchymosis, spit blood, hemoptysis, bleeding from five sense organs or subcutaneous tissue, hematochezia, metrorrhagia and metrostaxis, bloody flux, the intestinal parasitic diseases such as leukorrhagia and hook, ascarid, tapeworm.
Radix scutellariae: it is bitter, cold in nature, enter the heart, lung, gallbladder, large intestine channel.With excess fire is rushed down, except damp and hot, hemostasis, the function of miscarriage prevention.It cures mainly High fever polydipsia, cough with lung heat, damp-heat dysentery, jaundice, heat gonorrhea are spat, are defeated in battle, collapse, are leaked, red eye, swell pain, threatened abortion, carbuncle swells furunculosis.
Radix ampelopsis: bitter, pungent, cold nature.Enter the heart, lung, liver, spleen four to pass through.With clearing heat and detoxicating, eliminating stagnation to stop pain, myogenic sore Function.Treatment of ulcer pyogenic infections, scrofula, scald, wet sore, a kind of malaria, frightened epilepsy, bloody flux, intestines wind, anal fistula, leukorrhea, traumatic injury, wound Bleeding.
Radix Glycyrrhizae: it is sweet in flavor, it is mild-natured.Enter the heart, lung, spleen, stomach four to pass through.With with middle emergency, moistening lung, removing toxic substances, the function of coordinating the drug actions of a prescription. Cure mainly weakness of the spleen and the stomach, deficiency of food, abdominal pain loose stool, overstrain fever, consumptive lung disease cough, palpitaition, frightened epilepsy；It is raw to use, control abscess of throat, digestibility Ulcer, ulcer sores solve poisoning of drug and food poisoning.
The present invention prevents and treats the Traditional Chinese veterinary medicine oral solution and preparation method thereof of the atypical newcastle disease of chicken, for the physiological status of chicken And health status, by plurality of raw materials mix and match, scientific composition, it is main ingredient, hairyvein agrimony, plate that wherein polygonum cuspidate, radix scutellariae are clearing heat and detoxicating Lan Gen, rhizome of cyrtomium, radix ampelopsis, herba lysimachiae cooling blood and hemostasis, eliminating stagnation to stop pain, eliminating dampness and heat are ministerial drug, and Radix Astragali invigorating qi for consolidating superficies are assistant, Radix Glycyrrhizae tune It is to make with all medicines.Each raw material has complementary advantages, and using its mutual collaboration or resistant function, has clearing heat and detoxicating, eliminating dampness cool blood The effect of, it can be used for the prevention and treatment of the atypical newcastle disease of chicken, good effect, no drug residue.
Specific embodiment
In order to which technical solution of the present invention is more clearly understood, with reference to embodiments, the present invention is carried out further It is described in detail.
Embodiment 1:
The Traditional Chinese veterinary medicine oral solution of the atypical newcastle disease of prevention and treatment chicken, is made of the raw material of following weight:
20 kilograms of hairyvein agrimony, 24 kilograms of herba lysimachiae, 20 kilograms of Radix Isatidis, 14 kilograms of Radix Astragali, 20 kilograms of polygonum cuspidate, rhizome of cyrtomium 21,000 Gram, 21 kilograms of radix scutellariae, 14 kilograms of radix ampelopsis, 6 kilograms of Radix Glycyrrhizae；
The preparation method of the Traditional Chinese veterinary medicine oral solution of the atypical newcastle disease of prevention and treatment chicken, using following steps:
(1) each raw material (160 kilograms total) for weighing above-mentioned weight, puts into Chinese medicine extracting tank after mixing, Chinese medicine is added The water (i.e. 1120 kilograms) that 7 times of raw material weight impregnates 1 hour, decocts, is kept for 1 hour after boiling, tapping filters once to filter Liquid；The dregs of a decoction add 3 times of Chinese medicine material weight of water (i.e. 480 kilograms), decoct, are kept for 0.5 hour after boiling, tapping, filter Obtain secondary filtrate；
(2) merge first-time filtrate obtained and secondary filtrate in step (1), obtain merging filtrate, be placed in efficient concentration device It is concentrated under reduced pressure, medical fluid is concentrated into every milliliter of concentrate and is equivalent to 1g crude drug (i.e. 160 liters), obtains concentrate；
(3) it will be added in concentrate made from step (2) and account for concentrate weight than the sodium benzoate anti-corrosion for 0.3%, stirred With the filling Traditional Chinese veterinary medicine oral solution to get the prevention and treatment atypical newcastle disease of chicken of 250ml plastic drug package after mixing uniformly.
Usage and dosage: daily 1ml/kg weight, drinking-water are used in conjunction 4-5 days.
Embodiment 2:
The Traditional Chinese veterinary medicine oral solution of the atypical newcastle disease of prevention and treatment chicken, is made of the raw material of following weight: hairyvein agrimony 30,000 Gram, 36 kilograms of herba lysimachiae, 30 kilograms of Radix Isatidis, 21 kilograms of Radix Astragali, 30 kilograms of polygonum cuspidate, 24 kilograms of rhizome of cyrtomium, 24 kilograms of radix scutellariae, radix ampelopsis 21 kilograms, 9 kilograms of Radix Glycyrrhizae；
Preparation method and usage and dosage are the same as embodiment 1.
Embodiment 3:
The Traditional Chinese veterinary medicine oral solution of the atypical newcastle disease of prevention and treatment chicken, is made of the raw material of following weight: hairyvein agrimony 10,000 Gram, 12 kilograms of herba lysimachiae, 10 kilograms of Radix Isatidis, 7 kilograms of Radix Astragali, 10 kilograms of polygonum cuspidate, 18 kilograms of rhizome of cyrtomium, 18 kilograms of radix scutellariae, radix ampelopsis 7 Kilogram, 3 kilograms of Radix Glycyrrhizae；
Preparation method and usage and dosage are the same as embodiment 1.
Embodiment 4:
The Traditional Chinese veterinary medicine oral solution of the atypical newcastle disease of prevention and treatment chicken, is made of the raw material of following weight: hairyvein agrimony 15,000 Gram, 18 kilograms of herba lysimachiae, 15 kilograms of Radix Isatidis, 10.5 kilograms of Radix Astragali, 15 kilograms of polygonum cuspidate, 19.5 kilograms of rhizome of cyrtomium, radix scutellariae 19.5 thousand Gram, 10.5 kilograms of radix ampelopsis, 4.5 kilograms of Radix Glycyrrhizae；
Preparation method and usage and dosage are the same as embodiment 1.
Embodiment 5:
The Traditional Chinese veterinary medicine oral solution of the atypical newcastle disease of prevention and treatment chicken, is made of the raw material of following weight: hairyvein agrimony 25,000 Gram, 30 kilograms of herba lysimachiae, 25 kilograms of Radix Isatidis, 17.5 kilograms of Radix Astragali, 25 kilograms of polygonum cuspidate, 22.5 kilograms of rhizome of cyrtomium, radix scutellariae 22.5 thousand Gram, 17.5 kilograms of radix ampelopsis, 7.5 kilograms of Radix Glycyrrhizae；
Preparation method and usage and dosage are the same as embodiment 1.
Test example (one):
Traditional Chinese veterinary medicine oral solution for the verifying present invention prevention and treatment atypical newcastle disease of chicken imitates the prevention and treatment of newcastle disease virus Fruit, the In-vitro Inhibitory Effect of the present invention will be further illustrated by the following test examples oral solution to newcastle disease virus (NDV):
1 material
Experimental animal: 11 age in days SPF chicken embryos.
Virus: F48E8 plants of newcastle disease virus NDV, EID50It is 10-8.36/0.1mL。
Investigational agent: trial drug of the oral solution of 1-5 of embodiment of the present invention preparation as test example (one).
Comparison medicine: Moroxydine Hydrochloride, the production of Liaoning pharmacy head factory are made into the solution for standby of 0.1% concentration with PBS.
2 methods
2.1 egg inoculation
First use normal saline dilution at 200EID for F48E8 plants of NDV50Virus liquid, then by 1-5 system of the embodiment of the present invention Each 1mL of standby oral solution is mixed in microcentrifugal tube with equivalent NDV dilution respectively, after 37 DEG C of water-bath effect 0.5h, respectively It is inoculated with 11 age in days SPF chick embryo allantoic cavities, 0.2mL/ embryo, 10 pieces/group, as test group 1-5.
Physiological saline 1ml is mixed with equivalent NDV dilution, after 37 DEG C of water-bath 0.5h, the SPF chicken embryo urine of 11 ages in days of inoculation Blister cavities, 0.2mL/ embryo, 10 pieces/group, as positive controls.
0.1% Moroxydine Hydrochloride solution 1ml is mixed with equivalent NDV dilution, 37 DEG C of water-bath 0.5h, 11 ages in days of inoculation SPF chick embryo allantoic cavity, 0.2mL/ embryo, 10 pieces/group, as drug control group.
It after egg inoculation is complete, sets 37 DEG C of insulating boxs and is incubated for 96h, per a chicken embryo is checked for 24 hours, discard the dead germ in for 24 hours, Survival chicken embryo is set 4 DEG C of refrigerators and is saved after dead germ and 96h after for 24 hours.Record chicken embryo death time and quantity.
2.2 hemagglutination tests: being carried out using micro-agglutination method, measures NDV hemagglutinative titer (HA) in every piece of chick embryo allantoic liquid.
The analysis of 2.3 data: data analysis is carried out to the chicken embryo survival rate of each group, hemagglutinative titer using SPSS software, is determined Otherness between each group.
3 results
Chicken embryo is all survived after test 1-5 group 96 hours, Moroxydine Hydrochloride group and in positive controls chicken embryo 72 hours it is equal It is all dead, statistical analysis show to test between 1-5 group chicken embryo survival rate and positive controls there are extremely significant difference (p < 0.01), and Moroxydine Hydrochloride group and positive control group difference be not significant (p > 0.05).From the point of view of HA titre, 1-5 group HA is tested Titre is 0, positive controls 8.6, and Moroxydine Hydrochloride group is 7.8, and presence is extremely aobvious between test 1-5 group and positive controls It writes difference (p<0.01), and Moroxydine Hydrochloride group and positive control group difference be not significant (p>0.05).Test result is detailed in table 1。
1 test example of table (one) chicken embryo test result
Experiments have shown that oral solution of the present invention in vitro significantly inhibits NDV proliferation.
Test example (two):
The interaction between each ingredient of Traditional Chinese veterinary medicine oral solution in order to verify the present invention prevention and treatment atypical newcastle disease of chicken, It is further described below by way of test example.
1 material
Experimental animal: 11 age in days SPF chicken embryos.
Virus: F48E8 plants of newcastle disease virus NDV, EID50It is 10-8.36/0.1mL。
Investigational agent: oral solution and appoint from 1 oral solution, 9 kinds of raw materials of the embodiment of the present invention prepared by the embodiment of the present invention 1 Meaning choose it is one of, two kinds, three kinds, four kinds, five kinds, six kinds, seven kinds, eight kinds oral solution is made, as test example (two) Test group drug.
2 methods
2.1 egg inoculation
First use normal saline dilution at 200EID for F48E8 plants of NDV50Virus liquid, then by test example (two) each test group Each 1mL of drug is mixed in microcentrifugal tube with equivalent NDV dilution respectively, after 37 DEG C of water-bath effect 0.5h, is inoculated with 11 respectively Age in days SPF chick embryo allantoic cavity, 0.2mL/ embryo, 10 pieces/group, as test group.
Physiological saline 1ml is mixed with equivalent NDV dilution, after 37 DEG C of water-bath 0.5h, the SPF chicken embryo urine of 11 ages in days of inoculation Blister cavities, 0.2mL/ embryo, 10 pieces/group, as positive controls.
2.2 hemagglutination tests: being carried out using micro-agglutination method, measures NDV hemagglutinative titer (HA) in every piece of chick embryo allantoic liquid.
The analysis of 2.3 data: data analysis is carried out to the chicken embryo survival rate of each group, hemagglutinative titer using SPSS software, is determined Otherness between each group.
3 results
Chicken embryo is all dead in positive controls 48 hours, and HA titre is 8.6；Oral solution group (1-1 prepared by embodiment 1 Group), chicken embryo is all survived, and HA titre is 0；2-1 group is to 2-27 group, and each group chicken embryo survival rate is between 10%~60%, HA Titre is between 4.7~8.2.Statistical analysis shows oral solution group chicken embryo survival rate, HA titre and the positive prepared by embodiment 1 There are extremely significant difference (p < 0.01) between control group.From the point of view of test result, oral solution effect prepared by embodiment 1 is superior to it Its each test group.
Wherein 28 groups of experimental result is now chosen to be described as follows:
Each test group oral liquid component in 2 test example of table (two)
Each test group drug of test example (two) the preparation method is as follows:
(1) each raw material is weighed, is put into Chinese medicine extracting tank after mixing, 7 times of Chinese medicine material weight of water is added, it is small to impregnate 1 When, it decocts, is kept for 1 hour after boiling, tapping filters to obtain first-time filtrate；The dregs of a decoction add 3 times of Chinese medicine material weight of water, decoct It boils, is kept for 0.5 hour after boiling, tapping filters to obtain secondary filtrate；
(2) merge first-time filtrate obtained and secondary filtrate in step (1), obtain merging filtrate, be placed in efficient concentration device It is concentrated under reduced pressure, medical fluid is concentrated into every milliliter of concentrate and is equivalent to 1g crude drug, obtains concentrate；
(3) it will be added in concentrate made from step (2) and account for concentrate weight than the sodium benzoate anti-corrosion for 0.3%, stirred It is filling to get the test group oral solution with 250ml plastic drug package after mixing uniformly.
3 test example of table (two) chicken embryo test result
Experiments have shown that oral solution of the present invention significantly inhibits NDV proliferation, drug ratio is best, hence it is evident that excellent In other each group drugs.
Application examples:
Case 1:
Jinan farm, wherein the blue brown laying hen more than 8000 in sea that a henhouse is raised is only, chicken group starts to send out when 230 age in days Disease, diseased chicken spirit is depressed, and feed intake decline has respiratory symptom, draws green loose stool, and egg drop reduction is fragmentary daily dead.It cuts open Inspection is died of illness chicken, glandular stomach nipple slight bleeding, muscular stomach cuticula ulcer, has bleeding spot under cuticula, entire enteron aisle diffusivity goes out Blood, intestinal mucosa fall off, cecal tonsil swelling bleeding, the coronal fatty bleeding of cardiac muscle, tracheae hyperemia bleeding, ovarian follicle necrosis.According to Clinical symptoms and dissect lesion, are diagnosed as atypical newcastle disease.Oral solution of the present invention is begun to use to be treated, every chicken is every Its 1ml, 2 concentrations drinking-water medications of upper and lower noon point, is used in conjunction 5 days.After medication 3 days, chicken symptom starts to mitigate, and feed intake is significant Increase, the 7th day after medication, chicken group restores normal completely.
Case 2:
Weifang raiser raises 817 Broiler chicks 10000, and when 41 age in days starts to fall ill, and chicken group's spirit is depressed, feeding Amount decline, draws green loose stool, and individual chickens occur turn-taking, turn round the nervous symptoms such as neck, and dead more than 30 daily, dissect is died of illness chicken, gland Stomach nipple slight bleeding, muscular stomach cuticula bleed bottom, intestinal mucosa bleeding, there is jujube core shape ulcer in some gut associated lymphatic tissues, blind Intestinal tonsil body swelling bleeding, the heart are preced with fatty bleeding, and tunica mucosa tracheae bleeding is chronic newcastle disease through clinical diagnosis.Use this immediately Invention oral solution is treated, the daily 0.5ml of every chicken, and 2 concentrations drinking-water medications of upper and lower noon point, chicken group is dead after being used in conjunction 5 days Stop, spirit, appetite restore normal.

Claims (3)

1. a kind of Traditional Chinese veterinary medicine oral solution for preventing and treating the atypical newcastle disease of chicken, it is characterized in that: its active constituent is by following parts by weight Several raw materials are made: 10~30 parts of hairyvein agrimony, 12~36 parts of herba lysimachiae, 10~30 parts of Radix Isatidis, 7~21 parts of Radix Astragali, polygonum cuspidate 10 ~30 parts, 18~24 parts of rhizome of cyrtomium, 18~24 parts of radix scutellariae, 7~21 parts of radix ampelopsis, 3~9 parts of Radix Glycyrrhizae.
2. it is according to claim 1 prevention and treatment the atypical newcastle disease of chicken Traditional Chinese veterinary medicine oral solution, it is characterized in that: its activity at Divide and be prepared from the following raw materials in parts by weight: 20 parts of hairyvein agrimony, 24 parts of herba lysimachiae, 20 parts of Radix Isatidis, 14 parts of Radix Astragali, polygonum cuspidate 20 Part, 21 parts of rhizome of cyrtomium, 21 parts of radix scutellariae, 14 parts of radix ampelopsis, 6 parts of Radix Glycyrrhizae.
3. a kind of preparation side of the Traditional Chinese veterinary medicine oral solution of the prevention and treatment atypical newcastle disease of chicken according to claim 1 to 2 Method, it is characterized in that: including the following steps:
(1) each raw material mixing for weighing above-mentioned parts by weight is placed in Chinese medicine extracting tank, is added water to cook 2 times, method particularly includes: For the first time plus the water of 7 times of weight, immersion 1 hour are boiled 1 hour, and first-time filtrate is obtained after filtering；Add the water of 3 times of weight for the second time, It boils 0.5 hour, secondary filtrate is obtained after filtering；
(2) merge first-time filtrate obtained and secondary filtrate in step (1), obtain merging filtrate；Merging filtrate is concentrated under reduced pressure into Every milliliter of concentrate is equivalent to 1g crude drug, obtains concentrate；
(3) it will be added in concentrate made from step (2) and account for concentrate weight than the sodium benzoate for 0.3%, stirred evenly, i.e., Obtain the Traditional Chinese veterinary medicine oral solution of the prevention and treatment atypical newcastle disease of chicken.
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CN104288268A (en) * 2013-07-16 2015-01-21 李振达 Traditional Chinese medicinal formula for preventing and treating common diseases of chicken

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CN104288268A (en) * 2013-07-16 2015-01-21 李振达 Traditional Chinese medicinal formula for preventing and treating common diseases of chicken

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