CN106214548A - A kind of Skin whitening care cosmetics compositions and preparation method thereof - Google Patents
A kind of Skin whitening care cosmetics compositions and preparation method thereof Download PDFInfo
- Publication number
- CN106214548A CN106214548A CN201610710283.8A CN201610710283A CN106214548A CN 106214548 A CN106214548 A CN 106214548A CN 201610710283 A CN201610710283 A CN 201610710283A CN 106214548 A CN106214548 A CN 106214548A
- Authority
- CN
- China
- Prior art keywords
- component
- extract
- skin whitening
- care cosmetics
- agent
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/64—Proteins; Peptides; Derivatives or degradation products thereof
- A61K8/66—Enzymes
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q19/00—Preparations for care of the skin
- A61Q19/02—Preparations for care of the skin for chemically bleaching or whitening the skin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2800/00—Properties of cosmetic compositions or active ingredients thereof or formulation aids used therein and process related aspects
- A61K2800/74—Biological properties of particular ingredients
- A61K2800/78—Enzyme modulators, e.g. Enzyme agonists
- A61K2800/782—Enzyme inhibitors; Enzyme antagonists
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Mycology (AREA)
- Microbiology (AREA)
- Botany (AREA)
- Biotechnology (AREA)
- Engineering & Computer Science (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
Abstract
The invention discloses a kind of Skin whitening care cosmetics compositions and preparation method.The combination of these skin care item comprises component A, B component and component C especially.By weight percentage, described component A comprises emulsifying agent, squalane, hexadecanol, polydimethylsiloxane；B component comprises deionized water, thickening agent, polyhydric alcohol, wetting agent；Component C comprises deionization cooling water, leaf of Herba Origani extract, Flos Bombacis Malabarici extract, Fructus Melo extract, nonapeptide 1, western Radix rumicis acetosae extract, hydrolysis Europe Lee, bromelain, preservative, essence.Considering from experimental result, the present invention can be finally reached the result of Synergistic.Compared with single whitening agent, in the case of identical whitening effect, used by the present invention, whitening agent consumption is the most on the low side.And effect is more preferable.
Description
Technical field
The present invention relates to a kind of skin care item, belong to daily chemical products technical field, particularly relate to one and there is white-skinned face function
Composite skin care product.
Background technology
We look back the course of mankind's whitening, mainly experienced by with the next stage:
First stage: hide the white stage, skin will be spread on by white powder thing, it is achieved the whitening of physical property.This early stage
Whitewash honey etc. can only the skin whitening of apparent property, it is impossible to the skin whitening of essence, also can cause the problems such as clogging of pores.
Second stage strips off the whitening stage, becomes usually through physics mill stripping chemical attacks such as composition or fruit acid such as adding mineral
Point, mill stripping or stimulation epidermal keratinocyte make its fast-falling, thus reach to change the purpose of skin bleaching, such as scrubbing cream or skin-changing cream
Deng.Life-time service can cause skin immunity decline, be one typically cure the symptoms, not the disease morbid state whitening mode.
Local whitening stage phase III, i.e. by adding various whitening compositions, from the interference epidermis of local, difference position
Melanic formation or accelerate its catabolism, relatively for the former, third generation product is in the understanding of lightening mechanism and application side
There has been qualitative leap in face, but it still rests on the circumscribed whitening stage.And a lot of safety problem occurs in material choice:
Lead hydrargyrum--suppressing tryrosinase by the copper needed for replacing tryrosinase effect, bio-toxicity is big, destroys the multiple organ of human body；
Hydroquinone--cytotoxicity, destroys melanocyte；Rhododendrol--there is white macula in excessively whitening.
We analyze the formation determiner of human skin.
The color of human skin is affected by pigment system, is mainly determined by melanin therein.Melanin is by epidermis
The melanocyte of bottom produces.Melanocyte has dendroid to dash forward.This dendroid protrudes into epidermal keratinocyte, main merit
Can be to pass to horn cell with ripe melanin granule.
Ultraviolet irradiates and some other factor can cause epidermis cell to produce inflammatory factor, reactive oxygen free radical, α-rush
Black hormone etc..These materials some can promote melanocyte multiple fission, and generate tryrosinase, some can improve tyrosine
Enzymatic activity.Result causes melanin to accelerate to generate exactly.
After melanin generates, horn cell can be passed to by dendron.And along with horn cell gradually to external migration, final one
Rise and come off.And stay melanin in melanocyte and gradually digest as well as the passage of time, disperse.
It is metabolic imbalance that melanin generates on process nature, and degradation speed is less than aggregate velocity, long time sedimentation
Caused.The formation time is the most long, and melanin quantity between epidermis and corium is the most, piles up the tightst, is more difficult to
Scatter, it is difficult to metabolism is fallen.The traditional Chinese medical science interprets this as " causing QI-blood circulation not smooth, skin loses supports and the speckle that adds lustre to ".
The present invention is properly termed as the fourth stage of whitening, equalizes the whitening stage, i.e. considers each ring of skin-whitening
Joint.Generate inducement (ultraviolet irradiations) from melanin, melanin generate process to last melanin digest discharge process etc. each
Link considers.The raw material selecting gentle safety high carries out compatibility, and is finally reached collaborative whitening, the knot of efficient whitening
Really.
People are seeking one or more white-skinned face function composition compounded combination always, in order to reach to equalize the merit of skin whitening
Effect.But the most do not find ripe effective scheme.
Summary of the invention
It is an object of the invention to provide a kind of new Skin whitening care cosmetics compositions, it can consider each of skin-whitening
Individual link, reaches to equalize effect of skin whitening.
Another object of the present invention is to provide the preparation method of a kind of above-mentioned Skin whitening care cosmetics compositions.
To achieve these goals, the present invention adopts the following technical scheme that.
A kind of Skin whitening care cosmetics compositions, comprising white-skinned face function combination A, described white-skinned face function combination A is: leaf of Herba Origani extracts
Thing, Flos Bombacis Malabarici extract, Fructus Melo extract, nonapeptide-1, western Radix rumicis acetosae extract, hydrolysis Europe Lee, bromelain.
The Skin whitening care cosmetics compositions of the present invention, described white-skinned face function combination A comprises following components in percentage by weight:
Leaf of Herba Origani extract 0.1%-10%, Flos Bombacis Malabarici extract 0.1%-10%, Fructus Melo extract 0.1%-3%, nine
Peptide-10.1%-2%, western Radix rumicis acetosae extract 0.1%-10%, hydrolysis Europe Lee 0.1%-10%, bromelain 0.1%-
3%.
The Skin whitening care cosmetics compositions of the present invention, also comprises emulsifying agent 1%-3%, squalane 3%-8%, hexadecanol 1%-
3%, polydimethylsiloxane 0.5%-5%.
The Skin whitening care cosmetics compositions of the present invention, also comprises thickening agent 0.1%-3%, polyhydric alcohol 0.1%-10%, moisturizing
Agent 0.1%-10%.
The Skin whitening care cosmetics compositions of the present invention, described emulsifying agent is selected from: glyceryl stearate and PEG-100 stearic acid
Ester, stearoyl-glutamic acid sodium, cetearyl alcohol and Coco-Glucoside, C14-22 alcohol and the one of C12-20 alkyl androstanediol or
Person is two or more；
Described thickening agent is selected from AVC, carbomer, sodium acrylate/acryloyl two
One or more in N-methyltaurine sodium copolymer and 2-Methylpentadecane and Polyoxyethylene Sorbitan Monooleate, HANSHENGJIAO, cellulose；
One or more in butanediol, glycerol, propylene glycol of described polyhydric alcohol；
Described wetting agent is selected from one or more in glycerol, butanediol, hyaluronate sodium, glucosan, pantothenylol；
The Skin whitening care cosmetics compositions of the present invention, also comprises preservative 0.1%-0.8%, essence 0.01%-0.2%, goes
Ionized water surplus.
The Skin whitening care cosmetics compositions of the present invention, comprises component A, B component, component C；By weight percentage, described A group
Subpackage contains emulsifying agent 1%-3%, squalane 3%-8%, hexadecanol 1%-3%, polydimethylsiloxane 0.5%-5%；B component
Comprise deionized water 40%-80%, thickening agent 0.1%-3%, polyhydric alcohol 0.1%-10%, wetting agent 0.1%-10%；Component C
Comprise deionization cooling water 0.1%-5%, leaf of Herba Origani extract 0.1%-10%, Flos Bombacis Malabarici extract 0.1%-10%, Fructus Melo
Extract 0.1%-3%, nonapeptide-1 0.1%-2%, western Radix rumicis acetosae extract 0.1%-10%, hydrolysis Europe Lee 0.1%-10%,
Bromelain 0.1%-3%, preservative 0.1%-0.8%, essence 0.01%-0.2%.
The preparation method of the Skin whitening care cosmetics compositions of the present invention, comprises the steps:
1) component A adding oil phase pot, be heated to 80 DEG C, stirring and dissolving is complete；
2) B component adding emulsifying pot, be heated to 80 DEG C, stirring and dissolving is complete；
3) by component A suction emulsifying pot, emulsifying together with B component, insulation；
4) stirring cools to 35 DEG C, component C is added in emulsifying pot, stirs, and it is qualified to check, discharging.
The present invention has the advantages that.
According to the guidance of equilibrium whitening thought, the invention discloses a kind of Skin whitening care cosmetics group containing white-skinned face function component
Compound.
What is called of the present invention equilibrium whitening refers to:
1) inducement generated from pre-anti-melanin considers.Leaf of Herba Origani extract contained 50% polyphenol, through radiation in two hours
After irradiation, the active matter of 90% is constant.It is a kind of natural sunscreen, is also a kind of high anti-oxidizing activities thing, can be effective
Opposing DPPH and ultra-oxygen anion free radical.Add in the present invention combines and can be not added with any chemical sun, and be effective against
The ultraviolet irradiation to skin.And then reduce consequent inflammatory factor and oxygen-derived free radicals etc., and above-mentioned substance can make cheese
Propylhomoserin enzymatic activity increases, and then increases melanic generation.
2) from antiinflammatory, the release of suppression inflammatory factor considers.Flos Bombacis Malabarici in herbal tea five-flower tea, has the merit dispelling noxious dampness
Effect.Flos Bombacis Malabarici extract can promote that cell discharges Buchner's bodies, the release of suppression inflammatory factor, reduces because of UVA and UVB
Irradiate the quantity causing cell rupture dead, protect skin.And then reduce the facilitation that melanin is generated by inflammatory factor.Ancient
There is card side, " Kaibao Bencao ": main cholera attacked by pestiferous factors, red white chronic dysentery, except sweet hideing, scabies.Tooth worm pain, and boil clothes and contain it, water logging
Wash mesh, except skin is red." Nanning City's medicine will ": detumescence, dissipating blood stasis, pain relieving.Treating cough, only postnatal blood stasis is had a pain.
3) from antioxidation, free radical resisting considers.The south Provencal slips of the method quilt because it produces the Fructus Melo of high-quality forever
Known to the world.This place Charente Fructus Melo is containing the superoxide dismutase SOD far above other area Fructus Melos, and SOD is by science
Boundary is known as the strongest antioxidant.The Fructus Melo extract in this place confirms to have superpower antioxidation and free radical resisting after deliberation
Ability.In vitro technique result shows that it has the ability that well suppression melanin generates.
4) consider from suppression α-melanotropin.Nonapeptide-1 is the antagonist of α-melanotropin, by the combination with MC1-R,
Inhibit the combination of MC1-R Yu α-melanotropin, thus inhibit tyrosinase activity, eventually reduce melanic generation.
5) consider from suppression tyrosinase activity.Western Radix rumicis acetosae extract vitamin A, vitamin C and oxalic acid, suppress tyrosine
Enzyme is very competent.Melanic formation can be suppressed, desalinate pigmentation, reduce senile plaque, improve skin shine.Thus reach
To whitening effect.
6) from blocking the consideration of melanic transfer process.Hydrolysis Europe Lee is verified by experiments and keratinocyte can be suppressed black
The phagocytosis of pigment, thus reach whitening effect.And rest on the melanin in melanocyte and increase that to feed back to melanin thin
One signal black pigment of born of the same parents generates excess.This negative feedback mechanism can make melanocyte reduce continuation and produce melanin.
Meanwhile, rest on the melanin in melanocyte also can gradually disperse, digestion.
7) from accelerating the consideration of cuticular metabolism.After melanin enters horny layer, can come off together along with horny layer.
Bromelain may act on the aging cutin layer on human body skin, promotes it to degenerate, decompose, remove, and promotes skin new old generation
Thank, reduce the skin color depth phenomenon caused because of Exposure to Sunlight.Skin care is made to present good delicate state.
8) considering from experimental result, the present invention can be finally reached the result of Synergistic.Compared with single whitening agent,
In the case of identical whitening effect, used by the present invention, whitening agent consumption is the most on the low side.And effect is more preferable.
Detailed description of the invention
The invention provides a kind of Skin whitening care cosmetics compositions, it comprises white-skinned face function component: leaf of Herba Origani extract, kapok
Flower extract, Fructus Melo extract, nonapeptide-1, western Radix rumicis acetosae extract, hydrolysis Europe Lee, bromelain.
This leaf of Herba Origani extract has effect of natural sun-prevention, can pre-resisting ultraviolet radiation, weaken because of ultraviolet irradiate
The melanin caused excessively generates.This Flos Bombacis Malabarici extract has anti-inflammatory efficacy, can weaken the melanin that inflammatory factor causes
Excessively generate.This nonapeptide-1 has effect of suppression α-melanotropin, thus it is excessive to weaken the melanin that α-melanotropin causes
Generate.This western Radix rumicis acetosae extract can suppress tyrosinase activity, thus weaken melanin and generate.This hydrolysis Europe Lee can press down
Horn cell processed is to melanic phagocytosis, thus blocks melanin transhipment path, reaches whitening effect.
This bromelain can accelerate cuticular metabolism, thus accelerates melanic metabolism to reach whitening effect
Really.This Fructus Melo extract has effect of antioxidation, free radical resisting, can weaken the melanin that free radical causes and excessively generate.
Below by way of concrete preferred embodiment, the Skin whitening care cosmetics compositions of the present invention is further qualified, but the present invention
It is not limited in below example.
Percentage ratio in following example is weight percentage.The component raw material used is commercial products.
Embodiment 1
The Skin whitening care cosmetics compositions of the embodiment of the present invention, by weight percentage, comprises component A, B component, component C.
Wherein: described component A comprises stearoyl-glutamic acid sodium 0.5%, glyceryl stearate 1%, squalane 3%, 16
Alcohol 1%, polydimethylsiloxane 2%；B component comprises deionized water 65.1%, xanthan gum 0.5%, butanediol 5%, glucosan
3%；Component C comprises deionization cooling water 3%, leaf of Herba Origani extract 2%, Flos Bombacis Malabarici extract 2%, Fructus Melo extract 1%, nine
Peptide-1 1%, western Radix rumicis acetosae extract 5%, hydrolysis Europe Lee 3%, bromelain 1%, PE90100.8%, essence 0.1%.
The Skin whitening care cosmetics compositions its preparation method of the present invention, comprises the following steps:
1) component A adding oil phase pot, be heated to 80 DEG C, stirring and dissolving is complete；
2) B component adding emulsifying pot, be heated to 80 DEG C, stirring and dissolving is complete；
3) by component A suction emulsifying pot, emulsifying together with B component, insulation；
4) stirring cools to 35 DEG C, component C is added in emulsifying pot, stirs, and it is qualified to check, discharging.
Embodiment 2
The Skin whitening care cosmetics compositions of the embodiment of the present invention, by weight percentage, comprises component A, B component, component C.
Wherein: by weight percentage, described component A comprises glyceryl stearate and PEG-100 stearate 1.2%, whale
Wax stearyl alcohol and Coco-Glucoside 0.8%, squalane 5%, hexadecanol 1.5%, polydimethylsiloxane 3%；B component comprises
Deionized water 46.6%, carbomer 0.5%, triethanolamine 0.5%, glycerol 6%, glycerol 5%；Component C comprises deionization cooling
Water 4%, leaf of Herba Origani extract 4%, Flos Bombacis Malabarici extract 5%, Fructus Melo extract 2%, nonapeptide-11.5%, western Radix rumicis acetosae extract
6%, hydrolysis Europe Lee 5%, bromelain 1.5%, PE9010 0.8%, essence 0.1%.
The Skin whitening care cosmetics compositions its preparation method of the present invention, comprises the following steps:
1) component A adding oil phase pot, be heated to 80 DEG C, stirring and dissolving is complete；
2) B component adding emulsifying pot, be heated to 80 DEG C, stirring and dissolving is complete；
3) by component A suction emulsifying pot, emulsifying together with B component, insulation；
4) stirring cools to 35 DEG C, component C is added in emulsifying pot, stirs, and it is qualified to check, discharging.
Embodiment 3
The Skin whitening care cosmetics compositions of the embodiment of the present invention, by weight percentage, comprises component A, B component, component C.
Wherein: by weight percentage, described component A comprise glyceryl stearate and PEG-100 stearate 1.5%,
C14-22 alcohol and C12-20 alkyl androstanediol 1%, squalane 5%, hexadecanol 2%, polydimethylsiloxane 4%；B component comprises
Deionized water 40.1%, sodium acrylate/sodium acryloyldimethyl taurate copolymers and 2-Methylpentadecane and polysorbate-
801.5%, propylene glycol 4%, bextran 45 %；Component C comprises deionization cooling water 5%, leaf of Herba Origani extract 5%, Flos Bombacis Malabarici carry
Take thing 6%, Fructus Melo extract 3%, nonapeptide-1 2%, western Radix rumicis acetosae extract 7%, hydrolysis Europe Lee 6%, bromelain 2%,
PE9010 0.8%, essence 0.1%.
The Skin whitening care cosmetics compositions its preparation method of the present invention, comprises the following steps:
1) component A adding oil phase pot, be heated to 80 DEG C, stirring and dissolving is complete；
2) B component adding emulsifying pot, be heated to 80 DEG C, stirring and dissolving is complete；
3) by component A suction emulsifying pot, emulsifying together with B component, insulation；
4) stirring cools to 35 DEG C, component C is added in emulsifying pot, stirs, and it is qualified to check, discharging.
Embodiment 4
The Skin whitening care cosmetics compositions of the embodiment of the present invention, by weight percentage, comprises component A, B component, component C.
Wherein: by weight percentage, described component A comprise glyceryl stearate and PEG-100 stearate 1.5%,
C14-22 alcohol and C12-20 alkyl androstanediol 1%, squalane 5%, hexadecanol 2%, polydimethylsiloxane 4%；B component comprises
Deionized water 40.1%, sodium acrylate/sodium acryloyldimethyl taurate copolymers and 2-Methylpentadecane and polysorbate-
801.5%, glycerol 4%, bextran 45 %；Component C comprises deionization cooling water 5%, leaf of Herba Origani extract 5%, Flos Bombacis Malabarici extraction
Thing 6%, Fructus Melo extract 3%, nonapeptide-1 2%, western Radix rumicis acetosae extract 7%, hydrolysis Europe Lee 6%, bromelain 2%,
PE9010 0.8%, essence 0.1%.
The Skin whitening care cosmetics compositions its preparation method of the present invention, with embodiment 1.
Embodiment 5
The Skin whitening care cosmetics compositions of the embodiment of the present invention, by weight percentage, comprises component A, B component, component C.
Wherein: by weight percentage, described component A comprise glyceryl stearate and PEG-100 stearate 1.5%,
C14-22 alcohol and C12-20 alkyl androstanediol 1%, squalane 5%, hexadecanol 2%, polydimethylsiloxane 4%；B component comprises
Deionized water 40.1%, sodium acrylate/sodium acryloyldimethyl taurate copolymers and 2-Methylpentadecane and polysorbate-
801.5%, glycerol 4%, bextran 45 %；Component C comprises deionization cooling water 5%, leaf of Herba Origani extract 5%, Flos Bombacis Malabarici extraction
Thing 6%, Fructus Melo extract 3%, nonapeptide-1 2%, western Radix rumicis acetosae extract 7%, hydrolysis Europe Lee 6%, bromelain 2%,
PE9010 0.8%, essence 0.1%.
The Skin whitening care cosmetics compositions its preparation method of the present invention, with embodiment 1.
Whitening effect is tested
1, test sample:
Sample A described in embodiment 1 and blank sample B.
2, crowd is selected:
Age range 25-45 year
Each 50 of sex men and women
Test October in season-December
In Guangdong Province, region
3, process of the test:
Select the left and right arm of experimenter as tested region, random rotation labelling；
Test instrunment is used to carry out initial value data collection by technical staff；
In the tested district (the same area) crossed through clean water, every day is the most each once, and during experiment, recipient site is not
Other any cosmetics in addition to tested sample can be used；
Experimenter uses test article eight weeks continuously, and periodically carries out data acquisition during testing.
Statistical analysis, paired t-test, average.
In formula: the tested region of Tn changes over numerical value
T0 tested region initial value
KTn blank region changes over numerical value
KT0 blank region initial value
4, test instrunment
Dermal melanin and haemachrome test probe Mexameter MX18 (Germany CK company-MPA9)
5, test index:
MI value characterizes melanic index, and the measurement scope of instrument is 0～999, measures numerical value the highest, illustrates in skin black
Pigment content is the highest.
6, experimental result see table shown in 1.
The numerical value that table 1 test person group mean M1 changed with the testing time
Drawn by above experimental data:
Initial value rate of change relatively remains negative value, and has certain statistical significance.Blank relatively becomes
Rate also remains negative value.Finally conclude that embodiment 1 sample A has a good whitening effect, and over time
Passage whitening effect becomes apparent.
Effect application test example 2
2, security test
Method for testing security: select 30 triers, the skin care item of embodiment 1-5 are carried out patch test, passes through naked eyes
Observe, after 24 hours, observe dermoreaction.The extent of reaction and grade scoring standard see table shown in 2.
Table 2 patch test grade scoring standard
Result shows, in embodiment 1,30 people are negative, and 0 people is suspicious reaction.In case 2,30 people are negative instead
Should, 0 people is suspicious reaction.In case 3,30 people are negative, and 0 people is suspicious reaction.
According to " cosmetics health specification " 2007 editions human body skin patch experimental judgment standards, case 1-3 is to human body invariably
Good reaction.
The skin whitener of the present invention has good whitening effect, is provided simultaneously with higher safety mildness.
Effect application test example 3
3, lightening compositions of the present invention and tradition whitening agent are with effect addition contrast experiment
1, test sample:
Sample A: be prepared according to the method for embodiment 1, with embodiment 1 be different only in that following component is in formula
Consumption be respectively as follows: leaf of Herba Origani extract 0.5%, Flos Bombacis Malabarici extract 0.5%, Fructus Melo extract 0.4%, nonapeptide-10.2%,
Western Radix rumicis acetosae extract 0.5%, hydrolysis Europe Lee 0.5%, bromelain 0.2%,
Sample B1: prepare according to the method for embodiment 1, different from embodiment 1 are, with alpha-arbutin as whitening in B1
Component, and do not add the leaf of Herba Origani extract in embodiment 1, Flos Bombacis Malabarici extract, Fructus Melo extract, nonapeptide-1, western Radix rumicis acetosae
Extract, hydrolysis Europe Lee, bromelain；
Sample B2: prepare according to the method for embodiment 1, different from embodiment 1 are, substitute real in B1 with VC ethylether
Execute the leaf of Herba Origani extract in example, Flos Bombacis Malabarici extract, Fructus Melo extract, nonapeptide-1, western Radix rumicis acetosae extract, hydrolysis Europe Lee,
Bromelain；
Sample B3: prepare according to the method for embodiment 1, different from embodiment 1 are, substitute with nicotiamide and implement in B3
Leaf of Herba Origani extract in example, Flos Bombacis Malabarici extract, Fructus Melo extract, nonapeptide-1, western Radix rumicis acetosae extract, hydrolysis Europe Lee, spinach
Trailing plants protease.
2, crowd is selected:
Age range 25-45 year
Each 50 of sex men and women
Test October in season-December
In Guangdong Province, region
3, process of the test:
Select the left and right arm of experimenter as tested region, random rotation labelling；
Test instrunment is used to carry out initial value data collection by technical staff；
In the tested district (the same area) crossed through clean water, every day is the most each once, and during experiment, recipient site is not
Other any cosmetics in addition to tested sample can be used；
Experimenter uses test article eight weeks continuously, and periodically carries out data acquisition during testing.
4, test instrunment
Dermal melanin and haemachrome tester Mexameter MX18 (CK company of Germany)
5, test index:
MI value is for characterizing melanic index, and the measurement scope of instrument is 0～999, measures numerical value the highest, illustrates in skin
Melanin content is the highest.
6, experiment purpose
Test whitening agent addition required in the sample B1-B3 close with sample A white-skinned face function.
7, experimental result
After tested, finding that B1-B3 reaches the whitening effect identical with sample A, the addition of its whitening agent is respectively required for reaching
Consumption as shown in table 3 below.
Table 3 sample B1-B3 tests with sample A white-skinned face function
From experimental result, the present invention the most single whitening agent addition is less but whitening effect is good, and does not has after use
Irritant, product safe to use.
The above, be only presently preferred embodiments of the present invention, and the present invention not makees any pro forma restriction, therefore
Every without departing from technical solution of the present invention content, any simply repaiied according to what above example made by the technical spirit of the present invention
Change, equivalent variations and modification, all still fall within the range of technical solution of the present invention.
Claims (9)
1. a Skin whitening care cosmetics compositions, it is characterised in that: comprising white-skinned face function combination A, described white-skinned face function combination A is:
Leaf of Herba Origani extract, Flos Bombacis Malabarici extract, Fructus Melo extract, nonapeptide-1, western Radix rumicis acetosae extract, hydrolysis Europe Lee, bromelain
Enzyme.
2. as claimed in claim 1 Skin whitening care cosmetics compositions, it is characterised in that: described white-skinned face function combination A comprise with
The component of lower percentage by weight:
Leaf of Herba Origani extract 0.1%-10%, Flos Bombacis Malabarici extract 0.1%-10%, Fructus Melo extract 0.1%-3%, nonapeptide-
10.1%-2%, western Radix rumicis acetosae extract 0.1%-10%, hydrolysis Europe Lee 0.1%-10%, bromelain 0.1%-3%.
3. Skin whitening care cosmetics compositions as claimed in claim 2, it is characterised in that: also comprise emulsifying agent 1%-3%, spiny dogfish
Alkane 3%-8%, hexadecanol 1%-3%, polydimethylsiloxane 0.5%-5%.
4. as claimed in claim 3 Skin whitening care cosmetics compositions, it is characterised in that: also comprise thickening agent 0.1%-3%, many
Unit alcohol 0.1%-10%, wetting agent 0.1%-10%.
5. Skin whitening care cosmetics compositions as claimed in claim 4, it is characterised in that: described emulsifying agent is selected from glycerol stearate
Ester and PEG-100 stearate, stearoyl-glutamic acid sodium, cetearyl alcohol and Coco-Glucoside, C14-22 alcohol and C12-20
More than the one or two kinds of of alkyl androstanediol；
Described thickening agent is selected from AVC, carbomer, sodium acrylate/acryloyldimethyl
One or more in Taurate Copolymer and 2-Methylpentadecane and Polyoxyethylene Sorbitan Monooleate, HANSHENGJIAO, cellulose；
One or more in butanediol, glycerol, propylene glycol of described polyhydric alcohol；
Described wetting agent is selected from one or more in glycerol, butanediol, hyaluronate sodium, glucosan, pantothenylol.
6. the Skin whitening care cosmetics compositions as according to any one of claims 1-5, it is characterised in that: also comprise preservative
0.1%-0.8%, essence 0.01%-0.2%, deionized water surplus.
7. Skin whitening care cosmetics compositions as claimed in claim 1, it is characterised in that: comprise component A, B component, component C；Press
Percentage by weight meter, described component A comprises emulsifying agent 1%-3%, squalane 3%-8%, hexadecanol 1%-3%, poly dimethyl
Siloxanes 0.5%-5%；B component comprise deionized water 40%-80%, thickening agent 0.1%-3%, polyhydric alcohol 0.1%-10%,
Wetting agent 0.1%-10%；Component C comprises deionization cooling water 0.1%-5%, leaf of Herba Origani extract 0.1%-10%, Flos Bombacis Malabarici
Extract 0.1%-10%, Fructus Melo extract 0.1%-3%, nonapeptide-1 0.1%-2%, western Radix rumicis acetosae extract 0.1%-10%,
Hydrolysis Europe Lee 0.1%-10%, bromelain 0.1%-3%, preservative 0.1%-0.8%, essence 0.01%-0.2%.
8. Skin whitening care cosmetics compositions as claimed in claim 7, it is characterised in that: described emulsifying agent is selected from glycerol stearate
Ester and PEG-100 stearate, stearoyl-glutamic acid sodium, cetearyl alcohol and Coco-Glucoside, C14-22 alcohol and C12-20
More than the one or two kinds of of alkyl androstanediol；
Described thickening agent is selected from AVC, carbomer, sodium acrylate/acryloyldimethyl
One or more in Taurate Copolymer and 2-Methylpentadecane and Polyoxyethylene Sorbitan Monooleate, HANSHENGJIAO, cellulose；
One or more in butanediol, glycerol, propylene glycol of described polyhydric alcohol；
Described wetting agent is selected from one or more in glycerol, butanediol, hyaluronate sodium, glucosan, pantothenylol.
9. the preparation method of Skin whitening care cosmetics compositions as claimed in claim 7, it is characterised in that comprise the steps:
1) component A adding oil phase pot, be heated to 80 DEG C, stirring and dissolving is complete；
2) B component adding emulsifying pot, be heated to 80 DEG C, stirring and dissolving is complete；
3) by component A suction emulsifying pot, emulsifying together with B component, insulation；
4) stirring cools to 35 DEG C, component C is added in emulsifying pot, stirs, and it is qualified to check, discharging.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610710283.8A CN106214548B (en) | 2016-08-23 | 2016-08-23 | A kind of Skin whitening care cosmetics composition and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610710283.8A CN106214548B (en) | 2016-08-23 | 2016-08-23 | A kind of Skin whitening care cosmetics composition and preparation method thereof |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106214548A true CN106214548A (en) | 2016-12-14 |
| CN106214548B CN106214548B (en) | 2018-11-20 |
Family
ID=57554108
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610710283.8A Active CN106214548B (en) | 2016-08-23 | 2016-08-23 | A kind of Skin whitening care cosmetics composition and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106214548B (en) |
Cited By (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107049912A (en) * | 2017-01-10 | 2017-08-18 | 韩后化妆品股份有限公司 | Lightening compositions and its application containing green tea fermentation filtrate |
| CN107412061A (en) * | 2017-08-09 | 2017-12-01 | 广东丸美生物技术股份有限公司 | Skin matrix, preparation method and applications and cosmetics and preparation method thereof |
| CN108618993A (en) * | 2018-07-16 | 2018-10-09 | 广东格烯生物科技股份有限公司 | A kind of lightening compositions and its preparation method and application |
| CN108785121A (en) * | 2018-06-27 | 2018-11-13 | 广州达人研选生物科技有限公司 | A kind of whitening mask liquid and preparation method thereof |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103211725A (en) * | 2013-04-15 | 2013-07-24 | 广州环亚化妆品科技有限公司 | Vegetable fat composition cosmetic with whitening effect and preparation method of cosmetic |
| CN104352382A (en) * | 2014-10-20 | 2015-02-18 | 东莞市阿比亚能源科技有限公司 | Essence |
| CN105662908A (en) * | 2016-01-29 | 2016-06-15 | 广州康钰生物科技有限公司 | Gel matched with other water-in-oil emulsions for use and preparation method of gel |
-
2016
- 2016-08-23 CN CN201610710283.8A patent/CN106214548B/en active Active
Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN103211725A (en) * | 2013-04-15 | 2013-07-24 | 广州环亚化妆品科技有限公司 | Vegetable fat composition cosmetic with whitening effect and preparation method of cosmetic |
| CN104352382A (en) * | 2014-10-20 | 2015-02-18 | 东莞市阿比亚能源科技有限公司 | Essence |
| CN105662908A (en) * | 2016-01-29 | 2016-06-15 | 广州康钰生物科技有限公司 | Gel matched with other water-in-oil emulsions for use and preparation method of gel |
Cited By (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107049912A (en) * | 2017-01-10 | 2017-08-18 | 韩后化妆品股份有限公司 | Lightening compositions and its application containing green tea fermentation filtrate |
| CN107412061A (en) * | 2017-08-09 | 2017-12-01 | 广东丸美生物技术股份有限公司 | Skin matrix, preparation method and applications and cosmetics and preparation method thereof |
| CN107412061B (en) * | 2017-08-09 | 2019-09-13 | 广东丸美生物技术股份有限公司 | Skin matrix, preparation method and applications and cosmetics and preparation method thereof |
| CN108785121A (en) * | 2018-06-27 | 2018-11-13 | 广州达人研选生物科技有限公司 | A kind of whitening mask liquid and preparation method thereof |
| CN108785121B (en) * | 2018-06-27 | 2021-10-08 | 广州达人研选生物科技有限公司 | Whitening mask liquid and preparation method thereof |
| CN108618993A (en) * | 2018-07-16 | 2018-10-09 | 广东格烯生物科技股份有限公司 | A kind of lightening compositions and its preparation method and application |
| CN108618993B (en) * | 2018-07-16 | 2021-07-27 | 广东格烯生物科技股份有限公司 | Whitening composition and preparation method and application thereof |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106214548B (en) | 2018-11-20 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN102293733B (en) | Overall whitening and speckle removal skin care product | |
| CN106265236A (en) | A kind of lightening compositions and the skin care item containing said composition | |
| WO2015135313A1 (en) | Borojo skin care product and use thereof for natural moisturizing, anti-ageing, anti-uv, anti-anaphylaxis and whitening | |
| CN109528603A (en) | Lightening compositions, whitening brightening cream comprising lightening compositions and preparation method thereof | |
| CN101125119A (en) | Tibetan materia medica with whitening anti-senility function and application thereof | |
| CN103565730A (en) | Scented tea whitening skin-moistening cream and preparation method thereof | |
| TW200812638A (en) | Compositions comprising kakadu plum extract or acai berry extract | |
| CN106214548A (en) | A kind of Skin whitening care cosmetics compositions and preparation method thereof | |
| CN106176566A (en) | Cosmetic composition with white-skinned face function and preparation method thereof | |
| CN110859791B (en) | Skin whitening composition, application thereof and skin whitening mask | |
| CN112043661B (en) | Whitening aloe gel and preparation method thereof | |
| CN103340821A (en) | Whitening yellow fading cream | |
| CN109276529A (en) | A kind of lightening compositions and the whitening lotion comprising the composition | |
| CN110693780A (en) | Skin nourishing composition and application thereof, and skin nourishing mask liquid | |
| CN108379196A (en) | A kind of plant whitening spot-eliminating composition and its application | |
| CN113693990A (en) | Composition for effectively resisting oxidation and preserving moisture as well as preparation method and application thereof | |
| CN106727150A (en) | A kind of sun-proof skin care cosmetic composition and its application | |
| KR20170137552A (en) | Composition for improving skin condition comprising herb extracts mixture | |
| CN106963674A (en) | A kind of Whitening, spot composition and its application | |
| CN105596273A (en) | Soothing, moistening, brightening and whitening emulsion and preparation method thereof | |
| CN108014056A (en) | Skin relaxes liquid living and method | |
| CN108703911B (en) | Composition with moisturizing and whitening effects and preparation method and application thereof | |
| CN102961275A (en) | Araliaceae Acanthopanax trifoliatus ethanol extract-containing skin cosmetic | |
| CN108785196A (en) | A kind of composition for smoothing acne hole acne print and its application in cosmetics | |
| CN112842983B (en) | Herbal emulsion for sensitive muscle repair and preparation method thereof |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| SE01 | Entry into force of request for substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| GR01 | Patent grant | ||
| GR01 | Patent grant |