CN106212476A - A kind of fluorine-containing thiazole pyrrole ethyl ketone and the bactericidal composition of copper rosinate - Google Patents
A kind of fluorine-containing thiazole pyrrole ethyl ketone and the bactericidal composition of copper rosinate Download PDFInfo
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- CN106212476A CN106212476A CN201610627770.8A CN201610627770A CN106212476A CN 106212476 A CN106212476 A CN 106212476A CN 201610627770 A CN201610627770 A CN 201610627770A CN 106212476 A CN106212476 A CN 106212476A
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- Prior art keywords
- ethyl ketone
- pyrrole ethyl
- thiazole pyrrole
- copper rosinate
- fluorine
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- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/72—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms
- A01N43/74—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having rings with nitrogen atoms and oxygen or sulfur atoms as ring hetero atoms five-membered rings with one nitrogen atom and either one oxygen atom or one sulfur atom in positions 1,3
- A01N43/78—1,3-Thiazoles; Hydrogenated 1,3-thiazoles
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N37/00—Biocides, pest repellants or attractants, or plant growth regulators containing organic compounds containing a carbon atom having three bonds to hetero atoms with at the most two bonds to halogen, e.g. carboxylic acids
- A01N37/10—Aromatic or araliphatic carboxylic acids, or thio analogues thereof; Derivatives thereof
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- Life Sciences & Earth Sciences (AREA)
- Agronomy & Crop Science (AREA)
- Pest Control & Pesticides (AREA)
- Plant Pathology (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Dentistry (AREA)
- General Health & Medical Sciences (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Abstract
The invention discloses a kind of containing fluorine thiazole pyrrole ethyl ketone and the compositions of copper rosinate, in described compositions, the weight ratio of fluorine thiazole pyrrole ethyl ketone and copper rosinate is 1:30 30:1, being preferably 1:10 20:1, the compositions of the present invention shows preferable potentiation to downy mildew of garpe in described ratio range.
Description
Technical field
The present invention relates to composition pesticide field, particularly relate to a kind of fluorine-containing thiazole pyrrole ethyl ketone and the agriculture of copper rosinate
Drug composition.
Background technology
Downy mildew, late blight are the serious plant disease of danger to vegetables fruits crop.Data according to investigations, in Europe, annual valency
The pesticide being worth 1.8 hundred million Euros is used for preventing and treating downy mildew.And the economic loss that the whole world is caused because of the late blight of potato every year is up to 40
Hundred million Euros.
Fluorine thiazole pyrrole ethyl ketone, English common name oxathiapiprolin, CAS accession number 1003318-67-9, chemical name
1-(4-{4-[(5RS)-5-(2,6-difluorophenyl)-4,5-dihydro-1,2-azoles-3-base]-1,3-thiazol-2-yl }-1-piperidines
Base)-2-[5-methyl-3-(trifluoromethyl)-1H-pyrazol-1-yl] ethyl ketone, be Du Pont release in the near future there is brand-new effect machine
The antibacterial fluorine thiazole pyrrole ethyl ketone of reason then can be rated as the epoch-making product preventing and treating downy mildew and late blight.Fluorine thiazole pyrrole ethyl ketone is Du Pont
The first piperidyl thiazole isoxazolines antibacterial that company newly researches and develops, its structure includes isoxazole ring, pyrazole ring and thiazole ring.
This product lasts 14 years from being found to listing, has condensed the outstanding wisdom of Du Pont's scientists.This antibacterial is sick to Oomycete
Former bacterium has the action site of uniqueness, and downy mildew and epidemic disease to Rhizoma Solani tuber osi, Fructus Vitis viniferae, vegetable and other Featured crops have Zhuo
More preventive effect.
Copper rosinate is the new copper preparation sterilization pesticide of a kind of high-efficiency low-toxicity wide spectrum, has lasting period length, easy to use
New feature, overcome many shortcomings of former Bordeaux mixture, be the preferable antibacterial replacing Bordeaux mixture, and have prevention & protection
With treatment dual function, can be used for the frequently seen plants disease prevented and treated caused by multiple fungus and antibacterial, vegetable is had significantly thorn
Swash growth, can with other antibacterial alternately, spray effect is good.For preventing and treating downy mildew of cucurbits, epidemic disease, scab, anthrax
The various vegetables diseases such as disease, bacterial angular leaf spot, Fructus Solani melongenae damping-off, tomato late blight.
Different pesticide species compositions compound, and are the effective ways of preventing and treating corps diseases resistance generation, develop and grind
Study carefully efficiently, the complex preparation of low toxicity, low-residual there is small investment, R&D cycle short advantage, thus by researching and developing machine both at home and abroad
The attention of structure.Present inventor on the basis of lab screening and field control effectiveness test, filter out fluorine thiazole pyrrole ethyl ketone with
Copper rosinate compounds, and has obvious potentiation in certain scope to downy mildew.At present, there is no about fluorine thiazole
The report that pyrrole ethyl ketone and copper rosinate compound.
Summary of the invention
It is an object of the invention to provide a kind of Synergistic bactericidal composition being suitable for and agriculturally using, contribute to reducing pesticide
Usage amount, delay the drug-fast generation of pathogen.
For solving above-mentioned technical problem, the present invention adopts the following technical scheme that a kind of bactericidal composition, it is characterised in that
Active component includes fluorine thiazole pyrrole ethyl ketone and copper rosinate, and wherein, fluorine thiazole pyrrole ethyl ketone is 1:30-with the mass ratio of copper rosinate
30:1, preferably 1:10-20:1.
Further, in described bactericidal composition, the weight ratio of active component is 1-90%, preferably 20-60%.
Further, during the bactericidal composition of the present invention directly can be processed by pesticide, conventional preparation method is prepared as
For any one dosage form in Pesticide formulation, such as, can be cream, wettable powder, suspending agent, water dispersible granules, water
Emulsion, microemulsion, granule etc..
The compositions of the present invention can be the most blended with each material in the finished product preparation i.e. compositions of form offer, it is also possible to
Unit dose form provides, and is directly mixed in proportion in bucket or tank, is then diluted to required concentration before using.
Further, the compositions of the present invention can also add other agricultural active composition, such as antibacterial, insecticide,
The agricultural active composition such as herbicide, fertilizer.
The bactericidal composition of the present invention is applicable to prevent and kill off crops downy mildew, late blight etc..
Compared with prior art, the invention have the benefit that
(1), after the compositions of the present invention is compounding, there is in certain scope obvious synergistic function, preventive effect and single work
Property composition is compared and is significantly improved；
(2) in the compositions of the present invention, the active component mechanism of action is different, while effectively preventing and treating crop pest, permissible
Delay the drug-fast generation of pathogen, be conducive to delaying the service life of pesticide activity component, reduce further production cost
And use cost, the beneficially integrated control of resistance disease；
(3) the compositions preparation technology of the present invention is simple, is suitable for popularization and application in actual production.
Detailed description of the invention
In order to make the purpose of the present invention of the present invention, technical scheme and advantage clearer, the following tool of the present invention
Body embodiment illustrates, but the present invention is limited to absolutely not these examples.The following stated is only the preferable embodiment of the present invention, only
For explaining the present invention, but can not be therefore understands that be the restriction to the scope of the claims of the present invention.It should be pointed out that, it is all in the present invention
Spirit and principle within any amendment, equivalent or the improvement etc. made, should be included in protection scope of the present invention it
In, therefore, the protection domain of patent of the present invention should be as the criterion with claims.
One, example of formulations
1, embodiment 1:21% fluorine thiazole pyrrole ethyl ketone copper rosinate suspending agent (20:1)
Fluorine thiazole pyrrole ethyl ketone 20%
Copper rosinate 1%
Fatty alcohol-polyoxyethylene ether 6%
Sodium lignin sulfonate 4%
Arabic gum 2%
Organic silicone 2%
Potassium sorbate 0.2%
Ethylene glycol 0.8%
Deionized water surplus
2, embodiment 2:22% fluorine thiazole pyrrole ethyl ketone copper rosinate water dispersible granules (10:1)
Fluorine thiazole pyrrole ethyl ketone 20%
Copper rosinate 2%
Calcium lignosulfonate 5%
Ammonium sulfate 3%
Alkylphenol polyoxyethylene sulfate 6%
Hydroxymethyl cellulose 2%
Kaolin surplus
3, embodiment 3:30% fluorine thiazole pyrrole ethyl ketone copper rosinate wettable powder (1:1)
Fluorine thiazole pyrrole ethyl ketone 15%
Copper rosinate 15%
Sodium lignin sulfonate 5%
Sodium lauryl sulphate 6%
White carbon 5%
Kieselguhr surplus
4, embodiment 4:11% fluorine thiazole pyrrole ethyl ketone copper rosinate wettable powder (1:10)
Fluorine thiazole pyrrole ethyl ketone 1%
Copper rosinate 10%
Naphthalenesulfonate formaldehyde condensation compound 6%
Calcium lignosulfonate 4%
Pull open powder 5%
Kaolin surplus
Two, Toxicity Determination
Subjects: Plasmopara viticola
Test method: after effective inhibition concentration that prerun determines fluorine thiazole pyrrole ethyl ketone and copper rosinate, two kinds of medicaments are set not
Same Concentraton gradient, is carried out with reference to " farm-chemical indoor determination test rule antibacterial ", uses mycelial growth rate method to measure medicine
The agent virulence to crop pathogenic bacteria, measures colony diameter by decussation method after 72 h, calculates each process net growth, mycelial growth
Suppression ratio.Prevention effect is converted into probit value (y), and liquor strength (ug/mL) is converted into logarithm value (x), by minimum in terms of multiplication
Calculate concentration EC in virulence equation and suppression50, toxicity index and the co-toxicity coefficient (CTC) of medicament is calculated according to the abundant method of Sun Yun.Test knot
Fruit is shown in Table 1.
By table 1 result it can be seen that fluorine thiazole pyrrole ethyl ketone and copper rosinate weight ratio in the range of 1:30-30:1 to oenin
The co-toxicity coefficient of mildew, all more than 120, shows potentiation；Wherein, in the range of 1:10-20:1, compositions is to Portugal
The co-toxicity coefficient of grape downy mildew is all more than 140, and synergistic function becomes apparent from.
Three, field control effectiveness test
For verifying the practical application effect of the present invention further, the medicament of the embodiment of the present invention is used to carry out downy mildew of garpe field
The test of pesticide effectiveness.
Reagent agent: (1) 21% fluorine thiazole pyrrole ethyl ketone copper rosinate suspending agent (20:1)；
(2) 22% fluorine thiazole pyrrole ethyl ketone copper rosinate water dispersible granules (10:1)；
(3) 30% fluorine thiazole pyrrole ethyl ketone copper rosinate wettable powder (1:1)；
(4) 11% fluorine thiazole pyrrole ethyl ketone copper rosinate wettable powder (1:10)；
(5) comparative example 1:10% fluorine thiazole pyrrole ethyl ketone cream；
(6) comparative example 2:12% pine ester acid copper suspending agent.
Within 5 days, 10 days after medicine, investigating disease indexs and calculate preventive effect, result of the test is shown in Table 2.
By table 2 result it can be seen that the complex preparation of fluorine thiazole pyrrole ethyl ketone and the copper rosinate preventing and treating table to downy mildew of garpe
Reveal preferable lasting effect and quick-acting, hence it is evident that due to the preparation prevention effect of single active component, and in scope of medication, not
Find that described composite preparation produces poisoning to crop, show that the compositions safety of the present invention is also preferable, be worth on producing
Popularization and application.
Claims (4)
1. a bactericidal composition, it is characterised in that active component comprises fluorine thiazole pyrrole ethyl ketone and copper rosinate.
Bactericidal composition the most according to claim 1, it is characterised in that described fluorine thiazole pyrrole ethyl ketone and the weight of copper rosinate
Amount ratio is 1:30-30:1, preferably 1:10-20:1.
Bactericidal composition the most according to claim 1, it is characterised in that it can add other agricultural active composition such as
The agricultural active compositions such as antibacterial, Insecticides (tech) & Herbicides (tech), fertilizer.
4. the microbicide compositions described in claim any one of claim 1-3 is for preventing and treating the application of downy mildew of garpe.
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610627770.8A CN106212476A (en) | 2016-08-03 | 2016-08-03 | A kind of fluorine-containing thiazole pyrrole ethyl ketone and the bactericidal composition of copper rosinate |
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| CN201610627770.8A CN106212476A (en) | 2016-08-03 | 2016-08-03 | A kind of fluorine-containing thiazole pyrrole ethyl ketone and the bactericidal composition of copper rosinate |
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| CN106212476A true CN106212476A (en) | 2016-12-14 |
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Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108719308A (en) * | 2018-08-19 | 2018-11-02 | 安徽嘉联生物科技有限公司 | A kind of bactericidal composition of fluorine-containing thiazole pyrrole ethyl ketone and tiger glue adipic acid copper |
Citations (5)
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|---|---|---|---|---|
| CN101969781A (en) * | 2007-10-23 | 2011-02-09 | 杜邦公司 | Fungicidal compounds and mixtures |
| CN103478129A (en) * | 2013-10-12 | 2014-01-01 | 山东省烟台市农业科学研究院 | Agricultural compound bactericide and application thereof |
| CN104336033A (en) * | 2013-08-01 | 2015-02-11 | 陕西美邦农药有限公司 | A compound sterilization composition containing oxathiapiprolin and thiocarbamate |
| CN104336023A (en) * | 2013-08-08 | 2015-02-11 | 陕西美邦农药有限公司 | Sterilization composition containing oxathiapiprolin |
| CN104394693A (en) * | 2012-02-01 | 2015-03-04 | 纳幕尔杜邦公司 | Fungicidal pyrazole mixtures |
-
2016
- 2016-08-03 CN CN201610627770.8A patent/CN106212476A/en active Pending
Patent Citations (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101969781A (en) * | 2007-10-23 | 2011-02-09 | 杜邦公司 | Fungicidal compounds and mixtures |
| CN104394693A (en) * | 2012-02-01 | 2015-03-04 | 纳幕尔杜邦公司 | Fungicidal pyrazole mixtures |
| CN104336033A (en) * | 2013-08-01 | 2015-02-11 | 陕西美邦农药有限公司 | A compound sterilization composition containing oxathiapiprolin and thiocarbamate |
| CN104336023A (en) * | 2013-08-08 | 2015-02-11 | 陕西美邦农药有限公司 | Sterilization composition containing oxathiapiprolin |
| CN103478129A (en) * | 2013-10-12 | 2014-01-01 | 山东省烟台市农业科学研究院 | Agricultural compound bactericide and application thereof |
Non-Patent Citations (1)
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| 王运兵 等主编: "《无公害果园农药使用指南》", 31 May 2010 * |
Cited By (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN108719308A (en) * | 2018-08-19 | 2018-11-02 | 安徽嘉联生物科技有限公司 | A kind of bactericidal composition of fluorine-containing thiazole pyrrole ethyl ketone and tiger glue adipic acid copper |
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Application publication date: 20161214 |