CN106177817A - A kind of external used medicine treating acute soft tissue injury and preparation method thereof - Google Patents

A kind of external used medicine treating acute soft tissue injury and preparation method thereof Download PDF

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Publication number
CN106177817A
CN106177817A CN201610842909.0A CN201610842909A CN106177817A CN 106177817 A CN106177817 A CN 106177817A CN 201610842909 A CN201610842909 A CN 201610842909A CN 106177817 A CN106177817 A CN 106177817A
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radix
soft tissue
tissue injury
medicine
acute soft
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夏瑜
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Sichuan Jintang Haina Biomedical Technology Institute
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Sichuan Jintang Haina Biomedical Technology Institute
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/708Rheum (rhubarb)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/11Pteridophyta or Filicophyta (ferns)
    • A61K36/12Filicopsida or Pteridopsida
    • A61K36/126Drynaria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/51Gentianaceae (Gentian family)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/66Papaveraceae (Poppy family), e.g. bloodroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/744Gardenia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/80Scrophulariaceae (Figwort family)
    • A61K36/804Rehmannia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9066Curcuma, e.g. common turmeric, East Indian arrowroot or mango ginger
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0014Skin, i.e. galenical aspects of topical compositions
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/06Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
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  • Alternative & Traditional Medicine (AREA)
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  • Engineering & Computer Science (AREA)
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Abstract

The invention belongs to field of traditional Chinese, purpose is a kind of external used medicine treating acute soft tissue injury according to the traditional Chinese medical science, treatment acute soft tissue injury being recognized mechanism and providing, and each component of described medicine and mass parts ratio thereof are as follows: Radix Et Rhizoma Rhei 3~15g, Rhizoma Drynariae 10~25g, Radix Rehmanniae 10~32g, Cortex Phellodendri 8~16g, vinegar Rhizoma Corydalis 8~16g, Radix Gentianae Macrophyllae 8~16g, Sanguis Draxonis 1~1.5g, Radix Curcumae 3~12g, Fructus Gardeniae (stir-fry) 10~16g;The medicine that the present invention provides is the Chinese prescription of a treating both the principal and secondary aspects of a disease.

Description

A kind of external used medicine treating acute soft tissue injury and preparation method thereof
Technical field
The invention belongs to field of traditional Chinese, be specifically related to a kind of external used medicine treating acute soft tissue injury, especially It it is the field of external used medicine for acute soft tissue injury patient and preparation method thereof.
Background technology
Acute soft tissue injury means a series of urgency that the tissue outside the following skeleton of human motion system, skin is occurred Property dampen or (with) laceration, including muscle, ligament, fascia, tendon, synovial membrane, fat, joint capsule etc. tissue and peripheral nerve, The acute injury of the different situations of blood vessel, is clinical orthopedics department commonly encountered diseases, frequently-occurring disease.The pathological change of acute soft tissue injury removes Outside the disorganization directly contributed and dysfunction, mainly traumatic inflammation, hyperplasia and process of tissue reparation.Clinical main Local swelling to be shown as, pain, dysfunction, livid purple ecchymosis etc..Modern medicine mainly uses bag to acute soft tissue injury The physiotherapys such as bundle, partial closure, physical therapy, its curative effect is not the best enough, and rehabilitation duration is longer;And Drug therapy takes antiinflammatory town more The treatment of medicine bitterly, including non-steroid antiinflammatory immunoregulatory drugs, steroidal anti-inflammatory immune substance, desogestrel etc., but such drug side effect Relatively big, take the most in a large number and can affect many organs and the function of system.
So, just how to find a kind of medicine that can effectively treat acute soft tissue injury, be that we are badly in need of solving at present Problem certainly.
Summary of the invention
Along with the development of China's Chinese medicine, on treatment acute soft tissue injury, people gradually appreciate The advantage of Chinese traditional treatment acute soft tissue injury, and advantage, the pin such as good effect, instant effect, toxic and side effects be little over the course for the treatment of Present situation to existing western medical treatment acute soft tissue injury, it is an object of the invention to be that providing one to treat acute soft tissue damages The external used medicine of wound, to solve the most restorative problem of acute soft tissue injury patient.This medicine is with common Chinese medicine For raw material, by selecting rational medicine and mass parts ratio, can effectively treat above-mentioned acute soft tissue injury.
For reaching the purpose of foregoing invention, the technical solution adopted in the present invention is: provide one to treat acute soft tissue External used medicine of damage and preparation method thereof, it is characterised in that each component of described medicine and mass parts ratio thereof are as follows:
Radix Et Rhizoma Rhei 3~15g, Rhizoma Drynariae 10~25g, Radix Rehmanniae 10~32g, Cortex Phellodendri 8~16g, vinegar Rhizoma Corydalis 8~16g, Radix Gentianae Macrophyllae 8~ 16g, Sanguis Draxonis 1~1.5g, Radix Curcumae 3~12g, Fructus Gardeniae (stir-fry) 10~16g.
A kind of external used medicine treating acute soft tissue injury and preparation method thereof, it is characterised in that described medicine each Individual component and mass parts ratio thereof are as follows:
Radix Et Rhizoma Rhei 5~13g, Rhizoma Drynariae 12~23g, Radix Rehmanniae 12~28g, Cortex Phellodendri 10~14g, vinegar Rhizoma Corydalis 10~14g, Radix Gentianae Macrophyllae 10~ 14g, Sanguis Draxonis 1~1.4g, Radix Curcumae 5~11g, Fructus Gardeniae (stir-fry) 11~14g.
A kind of external used medicine treating acute soft tissue injury and preparation method thereof, it is characterised in that described " the most square Case " each component of medicine and mass parts ratio as follows:
Radix Et Rhizoma Rhei 12g, Rhizoma Drynariae 20g, Radix Rehmanniae 25g, Cortex Phellodendri 12g, vinegar Rhizoma Corydalis 12g, Radix Gentianae Macrophyllae 12g, Sanguis Draxonis 1.2g, Radix Curcumae 10g, Fructus Gardeniae (stir-fry) 12g.
A kind of external used medicine treating acute soft tissue injury and preparation method thereof, it is characterised in that described method includes Following steps are prepared from:
A, above-mentioned raw materials Chinese medicine is picked decontamination, dust, and after drying, be ground into according to mass parts ratio that superfine end is stand-by (to be used Ultra tiny machine grinds);
B, ground powder thing put into special-purpose stirring machine container be stirred, to be mixed uniformly after, obtain medicated powder;
C, take appropriate glycerol, stearic acid, triethanolamine, lanoline, vaseline, liquid paraffin, ethyl hydroxybenzoate and propyl hydroxybenzoate, And then heating (80 DEG C) is to melted, adds appropriate water emulsification the most again and i.e. obtains substrate in 10 minutes, when temperature is down to 50 DEG C, Add medicated powder, after agitated 10 minutes, mixing, sealed packaging, obtain externally-applied ointment.
The using method of the external used medicine of a kind of above-mentioned treatment acute soft tissue injury, it is characterised in that described user Method is: put on the skin by the externally-applied ointment prepared at the site of disease cleaned up, and sooner or later respectively applies ointment once, after treating 2~4 weeks, and symptom Fade away or fully recover.
Each raw material Chinese medicine in prescription of the present invention all has detailed note in Chinese Pharmacopoeia, China's dictionary and China's book on Chinese herbal medicine Carry.The present invention selects most common of which Chinese medicine to be raw material, gives full play to the pharmacological effect of each component:
Radix Et Rhizoma Rhei, nature and flavor: bitter, cold in nature, have and attack stagnant, clearing away damp-heat, pathogenic fire purging, removing heat from blood, blood stasis dispelling, effect of removing toxic substances, be used for treating reality Hot constipation, the accumulation of heat feeling of stuffiness in chest, damp and hot, dysentery, jaundice, gonorrhea, edema abdominal distention, dysuria, conjunctival congestion, laryngopharynx swelling and pain, aphtha of the mouth and tongue, Gastropyretic vomiting, spit blood, spit blood, epistaxis, have blood in stool, hematuria, blood-retention, amenorrhea, the stagnant stomachache of the stasis of blood in puerperal, abdominal mass accumulation, traumatic injury, heat The diseases such as poison carbuncle and ulcer, erysipelas, scald;
Rhizoma Drynariae, bitter, warm in nature, there is effect of the kidney invigorating bone strengthening, promoting blood circulation and stopping pain, be used for treating lumbago due to renal deficiency, foot and knee flaccidity, ear The diseases such as deaf, toothache, chronic diarrhea, the enuresis, injury and bone fracture and alopecia areata;
Radix Rehmanniae, nature and flavor: sweet, cold, there is clearing away heat and cooling blood, yin nourishing, effect of promoting the production of body fluid, be used for treating in calentura crimson tongue excessive thirst, the deficiency of YIN Heat, hectic fever due to YIN-deficiency consumptive fever, interior-heat are quenched one's thirst, are spitted blood, epistaxis, send out the diseases such as speckle dermexanthesis;
Cortex Phellodendri, nature and flavor: bitter, cold, there is heat clearing and damp drying, eliminating fire and detoxication, effect except hectic fever due to YIN-deficiency clearind deficient heat, be used for treating damp and hot rushing down The diseases such as dysentery, jaundice, leukorrhagia, pyretic stranguria, tinea pedis, flaccidity are warded off, hectic fever due to YIN-deficiency consumptive fever, night sweat, seminal emission, sore swollen toxin, eczema pruritus;
Vinegar Rhizoma Corydalis, nature and flavor: acrid, bitter, warm, nontoxic, have invigorate blood circulation, dissipating blood stasis, regulate the flow of vital energy, effect of pain relieving, be used for treating trusted subordinate's waist The diseases such as all pains of knee joint, menoxenia, lump in the abdomen, metrorrhagia, puerperal blood faints, lochiorrhea, traumatic injury;
Radix Gentianae Macrophyllae, nature and flavor: pungent, bitter, flat, there is effect of wind-damp dispelling, clearing away damp-heat, stopping numbness pain, be used for treating rheumatic arthralgia, muscle arteries and veins is arrested The diseases such as contraction, joint are ached, afternoon fever, infantile malnutrition heating;
Sanguis Draxonis, nature and flavor: sweet in the mouth, salty, property are put down, mild toxicity has effect of dissipating blood stasis analgesic therapy, hemostasis, promoting tissue regeneration and ulcer healing, falls for treatment Beat the diseases such as damage, ecchymoma due to internal injury, dysmenorrhea, postpartum stagnation stomachache, continuous bleeding due to traumatic injury, scrofula, ecthyma unhealed for long time and hemorrhoid;
Radix Curcumae, nature and flavor: acrid in the mouth, hardship, cold in nature, have invigorate blood circulation only can, promoting QI circulation for relieving depression, the removing heat from blood that clears away heart-fire, effect of depressed liver-energy dispersing and function of gallbladder promoting, be used for The treatment chest and abdomen side of body all pains of rib, dysmenorrhes, amenorrhea, abdominal mass caking, calentura coma, demented, infantile convulsion, spit blood, be defeated in battle standby, stranguria with blood, sand The diseases such as pouring, jaundice;
Fructus Gardeniae (is fried), nature and flavor: bitter, cold, has effect of heat clearing away, pathogenic fire purging, removing heat from blood, is used for treating calentura restlessness of asrhenia type and insomnia, jaundice, pouring Sick, quench one's thirst, conjunctival congestion, pharyngalgia, haematemesis, epistaxis, dysentery, hematuria, pathopyretic ulcer, sprain and swell and ache.
Medicine of the present invention is differential diagnosis of diseases based on Chinese traditional treatment acute soft tissue injury and the dialectical principle combined, from pharmacology Effect and mechanism of action are thought: demonstrate,prove with regard to acute soft tissue injury one, each raw material herbal medicine efficacy in medicine provided by the present invention Play altogether, above-mentioned disease is had good therapeutic effect.
Detailed description of the invention
The present invention is aiming at the treatment of above-mentioned acute soft tissue injury and a kind of Chinese medicine formula of proposing, uses this formula The medicine effect of preparation is good, and instant effect is the Chinese prescription of a treating both the principal and secondary aspects of a disease, is particularly suitable for Clinical practice.Below in conjunction with this The detailed description of the invention of invention is described in further detail:
Embodiment 1:
A kind of external used medicine treating acute soft tissue injury, it is characterised in that each component of described medicine and mass parts thereof Ratio is as follows:
Radix Et Rhizoma Rhei 12g, Rhizoma Drynariae 20g, Radix Rehmanniae 25g, Cortex Phellodendri 12g, vinegar Rhizoma Corydalis 12g, Radix Gentianae Macrophyllae 12g, Sanguis Draxonis 1.2g, Radix Curcumae 10g, Fructus Gardeniae (stir-fry) 12g.
Embodiment 2:
A kind of external used medicine treating acute soft tissue injury, it is characterised in that each component of described medicine and mass parts thereof Ratio is as follows:
Radix Et Rhizoma Rhei 13g, Rhizoma Drynariae 23g, Radix Rehmanniae 28g, Cortex Phellodendri 14g, vinegar Rhizoma Corydalis 14g, Radix Gentianae Macrophyllae 14g, Sanguis Draxonis 1.4g, Radix Curcumae 11g, Fructus Gardeniae (stir-fry) 14g.
Embodiment 3:
A kind of external used medicine treating acute soft tissue injury, it is characterised in that each component of described medicine and mass parts thereof Ratio is as follows:
Radix Et Rhizoma Rhei 15g, Rhizoma Drynariae 25g, Radix Rehmanniae 32g, Cortex Phellodendri 16g, vinegar Rhizoma Corydalis 16g, Radix Gentianae Macrophyllae 16g, Sanguis Draxonis 1.5g, Radix Curcumae 12g, Fructus Gardeniae (stir-fry) 16g.
Model case
Through clinical conditions acute soft tissue injury totally 725 example, the age is 410 examples of more than 42 years old, and only 315 examples are 42 years old Below.705 examples of recovery from illness in 725 example patients, 20 effective examples, total effective rate reaches 100%.

Claims (3)

1. the external used medicine treating acute soft tissue injury, it is characterised in that each component of described medicine and quality thereof Part ratio is as follows:
Radix Et Rhizoma Rhei 3~15g, Rhizoma Drynariae 10~25g, Radix Rehmanniae 10~32g, Cortex Phellodendri 8~16g, vinegar Rhizoma Corydalis 8~16g, Radix Gentianae Macrophyllae 8~ 16g, Sanguis Draxonis 1~1.5g, Radix Curcumae 3~12g, Fructus Gardeniae (stir-fry) 10~16g.
The external used medicine for the treatment of acute soft tissue injury the most according to claim 1, it is characterised in that described medicine each Individual component and mass parts ratio thereof are as follows:
Radix Et Rhizoma Rhei 5~13g, Rhizoma Drynariae 12~23g, Radix Rehmanniae 12~28g, Cortex Phellodendri 10~14g, vinegar Rhizoma Corydalis 10~14g, Radix Gentianae Macrophyllae 10~ 14g, Sanguis Draxonis 1~1.4g, Radix Curcumae 5~11g, Fructus Gardeniae (stir-fry) 11~14g.
3. according to the external used medicine of the treatment acute soft tissue injury described in claim 1 to 2, it is characterised in that described medicine Each component and mass parts ratio as follows:
Radix Et Rhizoma Rhei 12g, Rhizoma Drynariae 20g, Radix Rehmanniae 25g, Cortex Phellodendri 12g, vinegar Rhizoma Corydalis 12g, Radix Gentianae Macrophyllae 12g, Sanguis Draxonis 1.2g, Radix Curcumae 10g, Fructus Gardeniae (stir-fry) 12g.
CN201610842909.0A 2016-09-23 2016-09-23 A kind of external used medicine treating acute soft tissue injury and preparation method thereof Withdrawn CN106177817A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114028487A (en) * 2021-09-08 2022-02-11 山东省运动康复研究中心 Pharmaceutical composition and preparation for treating acute soft tissue injury

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101890121A (en) * 2009-05-21 2010-11-24 杨明 External medicinal composition for treating acute soft tissue injury and preparation method and application thereof

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101890121A (en) * 2009-05-21 2010-11-24 杨明 External medicinal composition for treating acute soft tissue injury and preparation method and application thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN114028487A (en) * 2021-09-08 2022-02-11 山东省运动康复研究中心 Pharmaceutical composition and preparation for treating acute soft tissue injury

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