CN106176003A - A kind of intravascular stent, its preparation method and application - Google Patents
A kind of intravascular stent, its preparation method and application Download PDFInfo
- Publication number
- CN106176003A CN106176003A CN201610525145.2A CN201610525145A CN106176003A CN 106176003 A CN106176003 A CN 106176003A CN 201610525145 A CN201610525145 A CN 201610525145A CN 106176003 A CN106176003 A CN 106176003A
- Authority
- CN
- China
- Prior art keywords
- intravascular stent
- repeated monomer
- section
- repeated
- intravascular
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
- 238000002360 preparation method Methods 0.000 title claims abstract description 7
- 239000000178 monomer Substances 0.000 claims abstract description 95
- 210000003111 iliac vein Anatomy 0.000 claims abstract description 28
- 210000004204 blood vessel Anatomy 0.000 claims description 13
- 238000000034 method Methods 0.000 claims description 10
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 8
- 239000000463 material Substances 0.000 claims description 8
- 229910052751 metal Inorganic materials 0.000 claims description 7
- 239000002184 metal Substances 0.000 claims description 7
- 229910045601 alloy Inorganic materials 0.000 claims description 6
- 239000000956 alloy Substances 0.000 claims description 6
- 229910000831 Steel Inorganic materials 0.000 claims description 5
- 229920002988 biodegradable polymer Polymers 0.000 claims description 5
- 239000004621 biodegradable polymer Substances 0.000 claims description 5
- 230000008569 process Effects 0.000 claims description 5
- 239000010959 steel Substances 0.000 claims description 5
- 229910000861 Mg alloy Inorganic materials 0.000 claims description 4
- 229910001362 Ta alloys Inorganic materials 0.000 claims description 3
- 229910001069 Ti alloy Inorganic materials 0.000 claims description 3
- 238000013461 design Methods 0.000 claims description 3
- 229910052742 iron Inorganic materials 0.000 claims description 3
- 238000005554 pickling Methods 0.000 claims description 3
- 230000008859 change Effects 0.000 claims description 2
- 150000002739 metals Chemical class 0.000 claims description 2
- 239000004744 fabric Substances 0.000 claims 1
- 210000003462 vein Anatomy 0.000 abstract description 7
- 208000007536 Thrombosis Diseases 0.000 abstract description 6
- 230000015572 biosynthetic process Effects 0.000 abstract description 5
- 230000006378 damage Effects 0.000 abstract description 3
- 230000000694 effects Effects 0.000 abstract description 3
- 239000007943 implant Substances 0.000 abstract description 3
- 206010070995 Vascular compression Diseases 0.000 description 5
- 208000011580 syndromic disease Diseases 0.000 description 5
- 239000008280 blood Substances 0.000 description 4
- 210000004369 blood Anatomy 0.000 description 4
- 210000000988 bone and bone Anatomy 0.000 description 4
- 238000010586 diagram Methods 0.000 description 4
- 210000003141 lower extremity Anatomy 0.000 description 4
- 208000027418 Wounds and injury Diseases 0.000 description 3
- 230000017531 blood circulation Effects 0.000 description 3
- 201000010099 disease Diseases 0.000 description 3
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 3
- 206010047249 Venous thrombosis Diseases 0.000 description 2
- 238000010276 construction Methods 0.000 description 2
- 238000001514 detection method Methods 0.000 description 2
- 238000009826 distribution Methods 0.000 description 2
- 238000005516 engineering process Methods 0.000 description 2
- PCHJSUWPFVWCPO-UHFFFAOYSA-N gold Chemical compound [Au] PCHJSUWPFVWCPO-UHFFFAOYSA-N 0.000 description 2
- 239000010931 gold Substances 0.000 description 2
- 229910052737 gold Inorganic materials 0.000 description 2
- 238000010147 laser engraving Methods 0.000 description 2
- 229910001000 nickel titanium Inorganic materials 0.000 description 2
- 238000011160 research Methods 0.000 description 2
- 230000000638 stimulation Effects 0.000 description 2
- 238000007631 vascular surgery Methods 0.000 description 2
- 229910018131 Al-Mn Inorganic materials 0.000 description 1
- 229910018461 Al—Mn Inorganic materials 0.000 description 1
- 229910000684 Cobalt-chrome Inorganic materials 0.000 description 1
- 206010051055 Deep vein thrombosis Diseases 0.000 description 1
- 229910000640 Fe alloy Inorganic materials 0.000 description 1
- 229910001021 Ferroalloy Inorganic materials 0.000 description 1
- FYYHWMGAXLPEAU-UHFFFAOYSA-N Magnesium Chemical compound [Mg] FYYHWMGAXLPEAU-UHFFFAOYSA-N 0.000 description 1
- 206010034272 Pelvic venous thrombosis Diseases 0.000 description 1
- 229920000954 Polyglycolide Polymers 0.000 description 1
- 208000006193 Pulmonary infarction Diseases 0.000 description 1
- 206010046996 Varicose vein Diseases 0.000 description 1
- WAIPAZQMEIHHTJ-UHFFFAOYSA-N [Cr].[Co] Chemical compound [Cr].[Co] WAIPAZQMEIHHTJ-UHFFFAOYSA-N 0.000 description 1
- HZEWFHLRYVTOIW-UHFFFAOYSA-N [Ti].[Ni] Chemical compound [Ti].[Ni] HZEWFHLRYVTOIW-UHFFFAOYSA-N 0.000 description 1
- 210000001015 abdomen Anatomy 0.000 description 1
- 239000000654 additive Substances 0.000 description 1
- 230000000996 additive effect Effects 0.000 description 1
- 230000002411 adverse Effects 0.000 description 1
- 238000013459 approach Methods 0.000 description 1
- 210000001367 artery Anatomy 0.000 description 1
- 230000008901 benefit Effects 0.000 description 1
- 238000009954 braiding Methods 0.000 description 1
- 239000010952 cobalt-chrome Substances 0.000 description 1
- 238000005520 cutting process Methods 0.000 description 1
- 230000007812 deficiency Effects 0.000 description 1
- 238000011161 development Methods 0.000 description 1
- 238000007599 discharging Methods 0.000 description 1
- 210000003191 femoral vein Anatomy 0.000 description 1
- 239000003292 glue Substances 0.000 description 1
- 210000003090 iliac artery Anatomy 0.000 description 1
- 210000003692 ilium Anatomy 0.000 description 1
- KHYBPSFKEHXSLX-UHFFFAOYSA-N iminotitanium Chemical compound [Ti]=N KHYBPSFKEHXSLX-UHFFFAOYSA-N 0.000 description 1
- 238000002513 implantation Methods 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 208000014674 injury Diseases 0.000 description 1
- 210000004731 jugular vein Anatomy 0.000 description 1
- 238000002372 labelling Methods 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000011777 magnesium Substances 0.000 description 1
- 229910052749 magnesium Inorganic materials 0.000 description 1
- 238000004519 manufacturing process Methods 0.000 description 1
- 238000012986 modification Methods 0.000 description 1
- 230000004048 modification Effects 0.000 description 1
- 229920000747 poly(lactic acid) Polymers 0.000 description 1
- 229920001610 polycaprolactone Polymers 0.000 description 1
- 239000004633 polyglycolic acid Substances 0.000 description 1
- 239000004626 polylactic acid Substances 0.000 description 1
- 230000007575 pulmonary infarction Effects 0.000 description 1
- 238000012827 research and development Methods 0.000 description 1
- 210000003752 saphenous vein Anatomy 0.000 description 1
- 230000008961 swelling Effects 0.000 description 1
- 208000024891 symptom Diseases 0.000 description 1
- 230000001225 therapeutic effect Effects 0.000 description 1
- 238000002560 therapeutic procedure Methods 0.000 description 1
- 230000008320 venous blood flow Effects 0.000 description 1
- 208000037997 venous disease Diseases 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/02—Prostheses implantable into the body
- A61F2/04—Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
- A61F2/06—Blood vessels
- A61F2/07—Stent-grafts
- A61F2002/072—Encapsulated stents, e.g. wire or whole stent embedded in lining
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91508—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other the meander having a difference in amplitude along the band
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91516—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other the meander having a change in frequency along the band
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/91533—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other characterised by the phase between adjacent bands
- A61F2002/91541—Adjacent bands are arranged out of phase
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F2/00—Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/82—Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
- A61F2/86—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure
- A61F2/90—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure
- A61F2/91—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes
- A61F2/915—Stents in a form characterised by the wire-like elements; Stents in the form characterised by a net-like or mesh-like structure characterised by a net-like or mesh-like structure made from perforated sheet material or tubes, e.g. perforated by laser cuts or etched holes with bands having a meander structure, adjacent bands being connected to each other
- A61F2002/9155—Adjacent bands being connected to each other
- A61F2002/91575—Adjacent bands being connected to each other connected peak to trough
Landscapes
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Biomedical Technology (AREA)
- Heart & Thoracic Surgery (AREA)
- Life Sciences & Earth Sciences (AREA)
- Cardiology (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Transplantation (AREA)
- Veterinary Medicine (AREA)
- Vascular Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Optics & Photonics (AREA)
- Physics & Mathematics (AREA)
- Gastroenterology & Hepatology (AREA)
- Pulmonology (AREA)
- Prostheses (AREA)
Abstract
The present invention relates to a kind of intravascular stent, its preparation method and application, intravascular stent includes positioning section and supporting section, location section includes multiple first repeated monomer, support section and include at least two support unit and at least one connection unit, support unit includes multiple second repeated monomer, the number of the first repeated monomer is different from the number of the second repeated monomer, it is positioned at the second repeated monomer supported before and after section in the support unit at two ends to connect one to one to constitute closed-loop structure with the second repeated monomer in another adjacent support unit by the first connection unit.The intravascular stent of the present invention is particularly well-suited to iliac vein, good to the support effect of iliac vein, and damage to wall of vein is little, intravascular stent can be prevented effectively from and implant the formation of secondary thrombus in after-poppet, in addition, the intravascular stent of the present invention can be good at positioning in iliac vein, improves the accuracy of release, easy and simple to handle.
Description
Technical field
The invention belongs to medical instruments field, be specifically related to a kind of intravascular stent, its preparation method and application.
Background technology
Venous disease is most commonly seen in vascular surgery disease, especially deep vein thrombosis of lower extremity and lower limb great saphenous vein
Varicose is the most common.And having in the reason that both diseases are formed is caused by iliac vein compression greatly.Iliac vein is subject to
Pressure syndrome (iliacveincompressionsyndrome, IVCS) means that iliac vein is oppressed by iliac artery, causes intracavity to glue
Even, narrow or inaccessible, thus there is the syndrome of range of clinical symptom, also known as May Thurner, Cockett syndrome.Ilium is quiet
Arteries and veins iliac vein incidence rate is 20%～34%.
Solving compression of vein to perform the operation in treatment, owing to needs enter abdomen operation, wound is relatively big, and patient is the most difficult always
To accept, therefore the operation number of cases at China's report is less.Cause a lot of patient's lower extremity swelling and distension to solve, have some patients because of
The blood stasis of blood is stagnant there is phlebothrombosis.From the development of eighties of last century the nineties interventional technique, domestic begin through balloon expandable,
The method of frame implantation solves iliac vein compression, and through the clinical treatment of nearly 20 years, the method for interventional therapy was vascular surgery
Boundary is accepted, simultaneously because wound is little, patient also can accept, and the most domestic have a lot of hospital to carry out this work.Simultaneously
Also have a lot of doctors that this technology is used for the patient of iliac vein thrombosis sequela.Along with being significantly increased of clinical disease number of cases,
And clinic uses the arterial bracket that bore is bigger to treat the patient of detection of iliac vein compression syndrome at present always, thus occur in that one
Individual important problem, i.e. in support, the probability of secondary thrombus is higher, and this is little with arterial bracket mesh, and the structure of iliac vein is led
Cause arterial bracket and must stretch into postcava 1-1.5 centimetre, and its support force does not causes designed by vein.
At present, the research report of lot of domestic and foreign shows, the support designed with detection of iliac vein compression syndrome as indication
Less.Domestic self-inflated bone vein support (utility model: 201520126120.6) that can be taken off effectively prevents deep veins of lower limb
The pulmonary infarction that thrombus breaks loose causes, after completing therapeutic purposes, can take out through jugular vein or femoral vein approach and avoid support long-term
Indwelling produces complication.For treating the narrow support of iliac vein (utility model: 201320053442.3) by nickel-titanium metal silk
The latticed webmaster that braiding is coiled into, webmaster front tube actinal surface is inclined-plane, and inclined-plane is 40 degree with the angle of webmaster section, and webmaster has
Oval labelling circle, it is achieved accurate positioning.But these bone vein supports yet suffer from some problems: be not all suitable for recovering
Bone venous blood flow state and increase blood flow, and it is easily caused the formation of thrombosis, thus be necessary to carry out novel bone venous branch
The research and development of frame and applied research.
Summary of the invention
The technical problem to be solved is to overcome the deficiencies in the prior art, it is provided that the blood vessel that a kind of structure is different props up
Frame, its preparation method and application, this intravascular stent has and is not easily formed thrombosis, and histocompatibility is good, the support force to vein
Suitably and not affect blood flow, simple in construction, easy to operate, accurate positioning, it is possible to meet the needs to iliac vein treatment in clinic.
For solving above technical problem, the present invention adopts the following technical scheme that
It is an object of the present invention to provide a kind of intravascular stent, it can become from the compressive state with the first cross-sectional diameter
Change the expansion state to the second cross-sectional diameter having had extended,
Described intravascular stent is included on the axis direction of described intravascular stent the location section being connected and supports section,
Described location section includes circumferentially distributed multiple first repeated monomers along described intravascular stent,
The described section that supports is included on the axis direction of described intravascular stent at least two support unit adjoined one another
Connecting unit with at least one, described support unit includes circumferentially distributed multiple second weights along described intravascular stent
Multiple monomer,
The number of the first described repeated monomer is different from the number of the second described repeated monomer, is positioned at described support section
Before and after two ends described support unit in the second repeated monomer by described first connection unit and adjacent another
The second repeated monomer in individual described support unit connects one to one to constitute closed-loop structure.
According to an embodiment of the invention, the number of the first described repeated monomer is single less than the second described repetition
The number of body.
Preferably, the number of the second described repeated monomer is 2 ~ 4 times of the number of the first described repeated monomer, described
The number of the first repeated monomer be 4 to 10.
Further, the described leading section supporting section connects the first developing cell.
According to a preferred aspect of the present invention, the leading section of described the second repeated monomer supporting section connects the
One developing cell, the number of the first developing cell can equal can not also wait with the number of the first described repeated monomer.
In the present invention, the first repeated monomer can be connected with the second repeated monomer, it is also possible to is connected with being connected unit.
According to an embodiment of the invention, the bearing of trend of described location section and the axle of described intravascular stent
The angle in line direction is 0 ° ~ 60 °.
Preferably, it is 0 ° when the bearing of trend of described location section with the angle of the axis direction of described intravascular stent
Time, described intravascular stent is substantially in cylinder；Bearing of trend and the axle of described intravascular stent when described location section
When line direction has angle, described location section is from the one end being connected with described support section towards leading section gradually
Direction away from the axis of described intravascular stent extends.
According to a preferred aspect of the present invention, the leading section of the first described repeated monomer is fillet, the circular arc of fillet
Internal diameter radius is more than or equal to 0.1mm.
According to a preferred aspect of the present invention, a length of 5 ~ 15mm of the first described repeated monomer, preferably 10 ~
15mm；The described a length of 40 ~ 140mm, preferably 60 ~ 120mm that support section；The thickness of described intravascular stent is 0.1 ~
0.3mm。
According to an embodiment of the invention, a length of 1 ~ 7mm of the second described repeated monomer, preferably 2 ~ 5mm.
Preferably, the described rearward end supporting section connects multiple second developing cell.It is further preferable that it is described
The number of the second developing cell is 3 to 10.
According to a specific embodiment of the present invention, the described unit that connects includes the week along described intravascular stent
To multiple connectors of distribution, the number of described connector is not more than the number of the second described repeated monomer.
Specifically, be positioned at described support before and after section the number of the described connector connected in unit at two ends with
The number of the second described repeated monomer is equal, is positioned at the described connection connected in unit at the described middle part supporting section
The number of body is less than the number of the second described repeated monomer.
Preferably, the width of described connector is 0.1 ~ 0.3mm.
In the present invention, the width of described connector is equal with the width of the first described repeated monomer.
In the present invention, the width of the second described repeated monomer can use regular width, such as 0.1 ~ 0.3mm.
According to a specific embodiment of the present invention, it is flat that the leading section of multiple the first described repeated monomers is formed
Face and the axis perpendicular of described intravascular stent.
According to a specific embodiment of the present invention, it is flat that the leading section of multiple the first described repeated monomers is formed
Face is 45 ° ~ 89 ° with the angle of the axis of described intravascular stent.
In the present invention, the material of described intravascular stent is rustless steel, memorial alloy, titanium alloy, tantalum alloy, the conjunction of cobalt chromium
One or more in gold, biodegradable metals, biodegradable polymer, magnesium alloy, pure iron.
It is a further object to provide the preparation method of a kind of above-mentioned intravascular stent, by material according to support Design
Path on drawing carries out cut, then processes obtain described intravascular stent through pickling, electrochemical process.
Certainly, the intravascular stent of the present invention can also use additive method to be prepared, and such as, weaves or welds.
Third object of the present invention is to provide a kind of stent delivery system, and it includes above-mentioned intravascular stent.
Fourth object of the present invention is to provide a kind of above-mentioned intravascular stent purposes in bifurcated vessels.
Preferably, the present invention provides a kind of above-mentioned intravascular stent purposes in iliac vein.
The present invention is defined as the front of intravascular stent with side, section place, location, is defined as blood supporting side, section place
The rear of pipe holder.
Angle defined in the present invention is the angle less than 90 ° formed between straight line and plane or straight line and straight line.
The total length of the intravascular stent in the present invention refers to that the leading section of the first repeated monomer is to the second developing cell
Long vertical dimension.The length of the first repeated monomer and the second repeated monomer refers to that the leading section of each repeated monomer is to rearward end
Vertical dimension.The length supporting section refers to the vertical dimension between the first developing cell to the second developing cell.
Due to the enforcement of technique scheme, the present invention compared with prior art has the advantage that
The intravascular stent of the present invention is particularly well-suited to iliac vein, good to the support effect of iliac vein, and the injury to wall of vein is little,
Can be prevented effectively from intravascular stent and implant the formation of secondary thrombus in after-poppet, the present invention is by closing the formation of supports section two ends
Ring structure, middle employing open loop structure, it is possible to well improve the support at two ends after the support force at two ends, beneficially support discharge
Uniformity and expansion uniformity, thus reduce the damage to blood vessel wall.Additionally, the intravascular stent of the present invention can be good at
Iliac vein positions, improves the accuracy of release, easy and simple to handle, the simple in construction of the intravascular stent of the present invention, produce
Convenient, low cost, thus have important practical significance and good potential applicability in clinical practice.
Accompanying drawing explanation
Fig. 1 is schematic diagram (bearing of trend of location section and the blood vessel that the intravascular stent of embodiment 1 is implanted in iliac vein
The axis direction of support is consistent)；
Fig. 2 is the structural representation that the intravascular stent of embodiment 1 is launched into plane；
Fig. 3 is the intravascular stent axonometric chart (bearing of trend of location section and the axle of intravascular stent at expansion state of embodiment 1
Line direction is consistent)；
Fig. 4 is the intravascular stent axonometric chart (location section is horn mouth shape) at expansion state of embodiment 1；
Fig. 5 is the enlarged drawing of the first connector；
Fig. 6 is the enlarged drawing of the first repeated monomer；
Fig. 7 is the structural representation that the intravascular stent of embodiment 2 is launched into plane；
Fig. 8 is the intravascular stent axonometric chart (bearing of trend of location section and the axle of intravascular stent at expansion state of embodiment 2
Line direction is consistent)；
Fig. 9 is the intravascular stent axonometric chart (location section is horn mouth shape) at expansion state of embodiment 2；
Figure 10 is the schematic diagram (location section is horn mouth shape) that the intravascular stent of embodiment 1 is implanted in iliac vein；
Figure 11 is that (bearing of trend of location section props up the schematic diagram that is implanted in iliac vein of the intravascular stent of embodiment 2 with blood vessel
The axis direction of frame is consistent)；
Figure 12 is the schematic diagram (location section is horn mouth shape) that the intravascular stent of embodiment 2 is implanted in iliac vein；
Wherein: 1, location section；11, the first repeated monomer；2, central support section；21, support unit；211, second repeats list
Body；22, unit is connected；221, connector；4, the first developing cell；5, the second developing cell；β is the front end of the first repeated monomer
The angle of the axis of the plane that portion is formed and intravascular stent；W1 is the width of connector；W3 is the width of the first repeated monomer；
W4 is the width of the second repeated monomer；L1 is the length of the first repeated monomer；L2 is the length supporting section；L4 is the second repetition
The length of monomer；L6 is the intravascular stent total length when expansion state.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described in detail, but the present invention is not limited to following enforcement
Example.
The intravascular stent of the present invention is primarily adapted for use in bifurcated vessels, is particularly well-suited in iliac vein (such as Fig. 1).By blood
During iliac vein implanted by pipe holder, intravascular stent is arranged in the carrier of stent delivery system, now, at intravascular stent
In compressive state, after intravascular stent is delivered to correct position by carrier, discharging intravascular stent, intravascular stent expands outwardly to
Expansion state, thus iliac vein is played a supporting role, intravascular stent has the first cross section when compressive state, at expansion shape
There is during state state the second cross section, and, the diameter of the first cross section is less than the diameter of the second cross section.In the present invention, the
One cross section and the second cross section are the cross section supporting section 2, and the axis perpendicular of this cross section and intravascular stent.This reality
Executing in example, the external diameter of the second cross section is 10 ~ 20mm, preferably 12 ~ 16mm.
The material of intravascular stent is rustless steel, memorial alloy, titanium alloy, tantalum alloy, cochrome, biodegradable gold
One or more in genus, biodegradable polymer, magnesium alloy, pure iron.Rustless steel can use SUS-316L rustless steel etc..Note
Recall alloy and can use Ni-Ti alloy, Cu-Al-Mn alloy etc..Cochrome can use CoCr-L605 cochrome etc..Biology can
Degraded metal is a kind of metal that can decompose in human body, the purest magnesium, magnesium alloy, pure iron and ferroalloy etc..Biodegradable
Polymer can be polylactic acid, polyglycolic acid, poly-(lactic acid-6-caprolactone), the biodegradable such as poly-(glycolic-6-caprolactone)
Polymer.In addition, it is possible in vivo in degradable metal, coat a kind of biodegradable polymer material to be used as blood vessel and prop up
The material of frame.
The intravascular stent of the present invention can utilize laser engraving one-shot forming.The production process of laser engraving: first, based on
Support Design drawing utilizes CAM to create cutting path；Secondly, metal or macromolecular material are carried out cut；Finally, pass through
Pickling and electrochemical process improve surface smoothness, make each edge shape mellow and full.
As shown in Figures 2 and 3, intravascular stent is included in the positioning area connected from front to back on the axis direction of intravascular stent
Section 1 and support section 2.
Location section 1 includes circumferentially distributed multiple first repeated monomers 11 along intravascular stent.
Support section 2 and be included at least two support unit 21 adjoined one another on the axis direction of intravascular stent and at least
One connects unit 22, and support unit 21 includes circumferentially distributed multiple second repeated monomers 211 along intravascular stent, connects
Unit 22 includes the circumferentially distributed multiple connectors 221 along intravascular stent, and the number of connector 221 is not more than the second repetition
The number of monomer 211.It is positioned at the second repeated monomer 211 supported before and after section 2 in the support unit 21 at two ends by first
Connect the connector 221 in unit 22 with the second repeated monomer 211 one_to_one corresponding in another adjacent support unit 21 even
Connect to constitute closed-loop structure, therefore, be positioned at and support the number of the connector 221 connected in unit 22 at two ends before and after section 2
Equal with the number of the second repeated monomer 211, be positioned at the middle part supporting section 2 the connector 221 connected in unit 22
Number is less than the number of the second repeated monomer 211, it is preferable that the number of the second repeated monomer 211 in each support unit 21 is
2 ~ 3 times of connector 221 number in each connection unit 22.Therefore, the support unit at the middle part supporting section 2 it is positioned at for opening
Ring structure.
The first repeated monomer 11 in the present invention and the structure of the second repeated monomer 211 can be can form hole any
Shape, such as V-type, grid type, rhombus etc..The connector 221 distribution mode on whole intravascular stent can be arbitrary, example
Such as form of straight lines, V-type, W type, S type, N-type etc..
In the present invention, the leading section connection supporting section 2 has the first developing cell 4, in the present embodiment, supports section 2
The leading section of the second repeated monomer 211 connects has the first developing cell 4, the setting of the first developing cell 4 to make intravascular stent energy
Enough well realization positions, and facilitates doctor to find point of release accurately.
In the present embodiment, the rearward end of the first repeated monomer 11 is connected with the leading section of the second repeated monomer 211.
In the present invention, the number of the first repeated monomer 11 is 4 to 10, and the number of the first developing cell 4 repeats with first
The number of monomer 11 is equal or different.
In the present invention, the rearward end connection supporting section 2 has multiple second developing cell 5, the number of the second developing cell 5
It is 3 to 10, and, the number of the second developing cell 5 is equal with the number of the first developing cell 4.In the present embodiment, second shows
Shadow unit 5 can be connected with support unit 21, or is connected with being connected unit 22, and the second developing cell 5 props up along blood vessel
The circumference of frame is uniformly distributed.
In the present invention, the number of the first repeated monomer 11 is different from the number of the second repeated monomer 211.Preferably, first
The number of repeated monomer 11 is less than the number of the second repeated monomer 211, and in the present embodiment, the number of the second repeated monomer 211 is
2 ~ 4 times of the number of the first repeated monomer 11, thus ensure that the aperture that the first repeated monomer 11 is formed is relatively big, as shown in Figure 1 will
After intravascular stent implants iliac vein, when location section 1 extends postcava, it is possible to avoid because the aperture of intravascular stent is less to leading
The formation of hyperamization bolt and avoid positioning section 1 blood flow of opposite iliac vein is impacted.
In the present embodiment, the bearing of trend of location section 1 is 0 ° ~ 45 ° with the angle of the axis direction of intravascular stent.Such as figure
Shown in 3, the bearing of trend of location section 1 is consistent with the axis direction of intravascular stent, i.e. angle is 0 °, and now, intravascular stent exists
Substantially in cylinder type during expansion state.As shown in Figure 4, the bearing of trend of location section 1 is deposited with the axis direction of intravascular stent
At angle, and, location section 1 gradually props up away from blood vessel towards leading section from the one end being connected with support section 2
The direction of the axis of frame extends, i.e. location section 1 is in the horn mouth shape the most gradually expanded outwardly.
In the present embodiment, the width W1(of connector 221 is as shown in Figure 5) it is 0.1 ~ 0.3mm.The width W1 of connector 221
With the width W3(of the first repeated monomer 11 as shown in Figure 6) equal.The width W4(of the second repeated monomer 211 is as shown in Figure 5) can
To use regular width, such as 0.1 ~ 0.3mm.
In the present embodiment, the thickness 0.1 ~ 0.3mm(of intravascular stent is not shown), the thickness of intravascular stent refers to that blood vessel props up
The external diameter of the cross section of frame and the difference of internal diameter.
In the present embodiment, the leading section of the first repeated monomer 11 is fillet, and the circular arc internal diameter radius of fillet is more than 0.1mm
(not shown), thus decrease the intravascular stent stimulation to blood vessel.
In the present embodiment, length L1 of the first repeated monomer 11 is 5 ~ 15mm, preferably 10 ~ 15mm, the first repeated monomer
The length of 11 is long, and the leading section of the first repeated monomer 11 can be caused to touch the blood vessel wall on opposite and cause the stimulation to blood vessel
Etc. adverse effect；The length of the first repeated monomer 11 is too short, then can affect intravascular stent location in iliac vein so that blood vessel
Support cannot stably be implanted in desired location.
Length L2 supporting section 2 is 40 ~ 140mm, preferably 60 ~ 120mm, and length L4 of the second repeated monomer 211 is 1
~ 7mm, preferably 2 ~ 5mm.That is, supporting section 2 and generally comprise 16 support units 21, certainly, the number of support unit 21 also may be used
To be adjusted according to actual needs.
The intravascular stent of the present invention total length L 6 when expansion state is 50 ~ 120mm, preferably 60 ~ 100mm.
Embodiment 1 is identical with the foregoing of embodiment 2, difference only with: in embodiment 1, multiple first repeated monomers
The plane that the leading section of 11 is formed and the axis perpendicular of intravascular stent, as shown in Figures 2 and 3.In embodiment 2, Duo Ge
The plane that the leading section of one repeated monomer 11 is formed and the axes intersect of intravascular stent, and multiple first repeated monomer 11
The plane that leading section is formed is 45 ° ~ 89 ° with the angle β of the axis of intravascular stent, as shown in Figs. 7-9, wherein, and Fig. 7 to 9
In, the plane that the leading section of multiple first repeated monomers 11 is formed is 70 ° with the angle β of the axis of intravascular stent, embodiment 2
In, the length of the first repeated monomer 11 gradually changes, but, its length range should be at the first repeated monomer of above-mentioned restriction
Within the length range of 11.
Above the present invention is described in detail, its object is to allow the personage being familiar with this art will appreciate that this
Invention content and be carried out, can not limit the scope of the invention with this, and the invention is not restricted to above-mentioned enforcement
Example, all equivalence changes made according to the spirit of the present invention or modification, all should contain within protection scope of the present invention.
Claims (16)
1. an intravascular stent, its can change to have had extended from the compressive state with the first cross-sectional diameter
The expansion state of two cross-sectional diameters, it is characterised in that:
Described intravascular stent is included on the axis direction of described intravascular stent the location section (1) and Support being connected
Section (2),
Described location section (1) includes circumferentially distributed multiple first repeated monomers (11) along described intravascular stent,
Described support section (2) is included on the axis direction of described intravascular stent at least two adjoined one another and supports single
Unit (21) and at least one connection unit (22), described support unit (21) includes dividing along the circumference of described intravascular stent
Multiple second repeated monomers (211) of cloth,
The number of described the first repeated monomer (11) is different from the number of described the second repeated monomer (211), is positioned at described
Support section (2) before and after two ends described support unit (21) in the second repeated monomer (211) by described the
One connects unit (22) with the second repeated monomer (211) one_to_one corresponding in adjacent another described support unit (21) even
Connect to constitute closed-loop structure.
Intravascular stent the most according to claim 1, it is characterised in that: the number of described the first repeated monomer (11) is less than
The number of described the second repeated monomer (211).
Intravascular stent the most according to claim 2, it is characterised in that: the number of described the second repeated monomer (211) is
2 ~ 4 times of the number of described the first repeated monomer (11), the number of described the first repeated monomer (11) is 4 to 10.
Intravascular stent the most according to claim 1, it is characterised in that: the leading section of described support section (2) connects to be had
First developing cell (4).
Intravascular stent the most according to claim 1, it is characterised in that: the bearing of trend of described location section (1) and institute
The angle of the axis direction of the intravascular stent stated is 0 ° ~ 60 °.
Intravascular stent the most according to claim 1, it is characterised in that: the leading section of described the first repeated monomer (11) is
Fillet, the circular arc internal diameter radius of fillet is more than or equal to 0.1mm.
Intravascular stent the most according to claim 1, it is characterised in that: described the first repeated monomer (11) a length of 5 ~
15mm, a length of 40 ~ 140mm of described support section (2), the thickness of described intravascular stent is 0.1 ~ 0.3mm.
Intravascular stent the most according to claim 1, it is characterised in that: the rearward end of described support section (2) connects to be had
Multiple second developing cells (5), the number of described the second developing cell (5) is 3 to 10.
Intravascular stent the most according to claim 1, it is characterised in that: described connection unit (22) includes along described
Circumferentially distributed multiple connectors (221) of intravascular stent, the number of described connector (221) is not more than described second
The number of repeated monomer (211), the width of described connector (221) is 0.1 ~ 0.3 mm.
Intravascular stent the most according to claim 9, it is characterised in that: it is positioned at two ends before and after described support section (2)
Described connection unit (22) in the number of connector (221) equal with the number of described the second repeated monomer (211),
The number of the connector (221) in the described connection unit (22) at the middle part being positioned at described support section (2) is less than described
The number of the second repeated monomer (211).
11. intravascular stents according to claim 1, it is characterised in that: before multiple described the first repeated monomers (11)
The plane that end is formed and the axis perpendicular of described intravascular stent.
12. intravascular stents according to claim 1, it is characterised in that: before multiple described the first repeated monomers (11)
The plane that end is formed is 45 ° ~ 89 ° with the angle of the axis of described intravascular stent.
13. intravascular stents according to claim 1, it is characterised in that: the material of described intravascular stent is rustless steel, note
Recall in alloy, titanium alloy, tantalum alloy, cochrome, biodegradable metals, biodegradable polymer, magnesium alloy, pure iron
One or more.
The preparation method of 14. 1 kinds of intravascular stents as according to any one of claim 1 to 13, it is characterised in that: by material
Carry out cut according to the path on support Design drawing, then process obtain described blood vessel through pickling, electrochemical process
Support.
15. 1 kinds of intravascular stents as according to any one of claim 1 to 13 purposes in bifurcated vessels.
16. 1 kinds of intravascular stents as according to any one of claim 1 to 13 purposes in iliac vein.
Priority Applications (5)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610525145.2A CN106176003B (en) | 2016-07-06 | 2016-07-06 | A kind of intravascular stent, preparation method and application |
| PCT/CN2016/089590 WO2017185529A1 (en) | 2016-04-27 | 2016-07-11 | Vascular stent, preparation method therefor, and application thereof |
| EP16900039.5A EP3449878A4 (en) | 2016-04-27 | 2016-07-11 | Vascular stent, preparation method therefor, and application thereof |
| US15/737,365 US10695201B2 (en) | 2016-04-27 | 2016-07-11 | Intravascular stent, preparation method and use thereof |
| US16/878,320 US11471309B2 (en) | 2016-04-27 | 2020-05-19 | Intravascular stent, preparation method and use thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610525145.2A CN106176003B (en) | 2016-07-06 | 2016-07-06 | A kind of intravascular stent, preparation method and application |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106176003A true CN106176003A (en) | 2016-12-07 |
| CN106176003B CN106176003B (en) | 2018-12-28 |
Family
ID=57466393
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610525145.2A Active CN106176003B (en) | 2016-04-27 | 2016-07-06 | A kind of intravascular stent, preparation method and application |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106176003B (en) |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106821563A (en) * | 2017-03-15 | 2017-06-13 | 山东吉威医疗制品有限公司 | A kind of support for lesion at branch vessel opening |
| CN110292471A (en) * | 2019-08-01 | 2019-10-01 | 吴忠隐 | A kind of vein bracket |
| CN110613540A (en) * | 2019-10-24 | 2019-12-27 | 上海唯域医疗科技有限公司 | Blood vessel implantation stent |
| CN111818882A (en) * | 2018-03-09 | 2020-10-23 | 维斯帕医疗公司 | Implantable stent |
| WO2021253216A1 (en) * | 2020-06-16 | 2021-12-23 | Suzhou Venmed Technology Co., Ltd. | Intravascular stent |
Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN2710576Y (en) * | 2004-03-10 | 2005-07-20 | 杨大智 | Laser curved 'quasi sine' tube type nickel titanium alloy support |
| CN1691924A (en) * | 2002-09-27 | 2005-11-02 | 医学技术设备公司 | Implantable stent with modified ends |
| US20070119295A1 (en) * | 2002-11-15 | 2007-05-31 | Scimed Life Systems, Inc. | Braided stent and method for its manufacture |
| CN2917584Y (en) * | 2004-09-30 | 2007-07-04 | 大连理工大学 | Laser etching nickel-titanium alloy self-swelling type jumping-proof supporting stand |
| US20090118810A1 (en) * | 2002-09-27 | 2009-05-07 | Medlogics Device Corporation | Stent assembly system |
| CN203408130U (en) * | 2013-08-12 | 2014-01-29 | 万瑞飞鸿(北京)医疗器材有限公司 | Self-expansion carotid artery covered stent |
| CN105726174A (en) * | 2016-04-27 | 2016-07-06 | 苏州天鸿盛捷医疗器械有限公司 | Intravascular stent and preparation method and application thereof |
-
2016
- 2016-07-06 CN CN201610525145.2A patent/CN106176003B/en active Active
Patent Citations (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1691924A (en) * | 2002-09-27 | 2005-11-02 | 医学技术设备公司 | Implantable stent with modified ends |
| US20090118810A1 (en) * | 2002-09-27 | 2009-05-07 | Medlogics Device Corporation | Stent assembly system |
| US20070119295A1 (en) * | 2002-11-15 | 2007-05-31 | Scimed Life Systems, Inc. | Braided stent and method for its manufacture |
| CN2710576Y (en) * | 2004-03-10 | 2005-07-20 | 杨大智 | Laser curved 'quasi sine' tube type nickel titanium alloy support |
| CN2917584Y (en) * | 2004-09-30 | 2007-07-04 | 大连理工大学 | Laser etching nickel-titanium alloy self-swelling type jumping-proof supporting stand |
| CN203408130U (en) * | 2013-08-12 | 2014-01-29 | 万瑞飞鸿(北京)医疗器材有限公司 | Self-expansion carotid artery covered stent |
| CN105726174A (en) * | 2016-04-27 | 2016-07-06 | 苏州天鸿盛捷医疗器械有限公司 | Intravascular stent and preparation method and application thereof |
Cited By (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN106821563A (en) * | 2017-03-15 | 2017-06-13 | 山东吉威医疗制品有限公司 | A kind of support for lesion at branch vessel opening |
| CN111818882A (en) * | 2018-03-09 | 2020-10-23 | 维斯帕医疗公司 | Implantable stent |
| CN110292471A (en) * | 2019-08-01 | 2019-10-01 | 吴忠隐 | A kind of vein bracket |
| CN110613540A (en) * | 2019-10-24 | 2019-12-27 | 上海唯域医疗科技有限公司 | Blood vessel implantation stent |
| WO2021253216A1 (en) * | 2020-06-16 | 2021-12-23 | Suzhou Venmed Technology Co., Ltd. | Intravascular stent |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106176003B (en) | 2018-12-28 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| CN105726174B (en) | A kind of intravascular stent, preparation method and application | |
| CN106176003A (en) | A kind of intravascular stent, its preparation method and application | |
| CN204951247U (en) | Biodegradable metal blood vessel support | |
| CN106691647B (en) | A kind of biodegradable metals intravascular stent and its application | |
| CN105726178B (en) | A kind of intravascular stent, its preparation method and application | |
| CN105796220A (en) | Intravascular stent and preparation method and application thereof | |
| WO2011131115A1 (en) | Stent for bifurcated vessel | |
| CN110393605B (en) | Aortic arch area branch tectorial membrane support blood vessel composite set | |
| CN103550017A (en) | Intravascular stent applicable to conical blood vessel | |
| US11471309B2 (en) | Intravascular stent, preparation method and use thereof | |
| CN207168613U (en) | A kind of intravascular stent | |
| US10695201B2 (en) | Intravascular stent, preparation method and use thereof | |
| CN203988521U (en) | A kind of asymmetric conical intravascular stent | |
| CN203425071U (en) | Blood vessel stent suitable for conical blood vessel | |
| CN103300951A (en) | Vertebral artery stent | |
| CN106236342A (en) | A kind of implanted complete biological absorbable blood vessel polymer support | |
| WO2009052703A1 (en) | Nested stent in body lumen | |
| CN206534738U (en) | Aorta tectorial membrane stent | |
| CN206342572U (en) | A kind of intravascular stent | |
| CN107874877A (en) | Aorta tectorial membrane stent | |
| CN206372164U (en) | A kind of intravascular stent | |
| CN105796219B (en) | A kind of intravascular stent, its preparation method and application | |
| CN111374809B (en) | Vertebral artery stent | |
| CN107550611A (en) | A kind of intravascular stent | |
| CN109602523B (en) | Recoverable medicine support |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| CB03 | Change of inventor or designer information | ||
| CB03 | Change of inventor or designer information |
Inventor after: Feng Haiquan Inventor after: Li Xiaoqiang Inventor after: Cao Ping Inventor after: Wang Xiaotian Inventor after: Tang Lie Inventor after: Wang Yonggang Inventor before: Feng Haiquan Inventor before: Li Xiaoqiang Inventor before: Wang Xiaotian Inventor before: Tang Lie Inventor before: Wang Yonggang |
|
| GR01 | Patent grant | ||
| GR01 | Patent grant | ||
| CP03 | Change of name, title or address | ||
| CP03 | Change of name, title or address |
Address after: Rooms 202, 501, and 502, Building 7, No. 188 Fuchunjiang Road, High tech Zone, Suzhou City, Jiangsu Province, 215000 Patentee after: SUZHOU VENMED TECHNOLOGY Co.,Ltd. Country or region after: China Address before: 215163 south 2nd floor, building 11, No.8 Jinfeng Road, science and Technology City, Suzhou high tech Zone, Jiangsu Province Patentee before: SUZHOU VENMED TECHNOLOGY Co.,Ltd. Country or region before: China |