CN106137186A - The high reliability acquisition method of EEG signals - Google Patents

The high reliability acquisition method of EEG signals Download PDF

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CN106137186A
CN106137186A CN201610565381.7A CN201610565381A CN106137186A CN 106137186 A CN106137186 A CN 106137186A CN 201610565381 A CN201610565381 A CN 201610565381A CN 106137186 A CN106137186 A CN 106137186A
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eeg signals
programmable amplifier
sensor
amplification
high reliability
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CN106137186B (en
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周琳
陈林瑞
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Sichuan Dongding Lizhi Information Technology Co Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/24Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
    • A61B5/316Modalities, i.e. specific diagnostic methods
    • A61B5/369Electroencephalography [EEG]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0004Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network characterised by the type of physiological signal transmitted
    • A61B5/0006ECG or EEG signals
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/68Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient
    • A61B5/6801Arrangements of detecting, measuring or recording means, e.g. sensors, in relation to patient specially adapted to be attached to or worn on the body surface
    • A61B5/6802Sensor mounted on worn items
    • A61B5/6803Head-worn items, e.g. helmets, masks, headphones or goggles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7203Signal processing specially adapted for physiological signals or for diagnostic purposes for noise prevention, reduction or removal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7221Determining signal validity, reliability or quality
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation

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Abstract

In order to improve the wireless reliability of brain wave wireless collection scheme, solid foundation is provided for accurately processing of eeg signal and ensures reliably, the invention provides the high reliability acquisition method of a kind of EEG signals, including arranging initial EEG signals sensor array and auxiliary EEG signals sensor array, and through the multiple working cycle started from the 0th moment T0, determine the duty of each EEG signals sensor, and and then the step such as the amplification that each described programmable amplifier is set when the second moment T2.Auxiliary EEG signals sensor according to present invention original creation, the EEG signals that combining wireless transmission unit sends, can at a high speed, process the EEG signals that must process efficiently, the signal to noise ratio making EEG signals to be analyzed improves 30% 40%, makes eeg signal acquisition reliability averagely improve about 40% 55%.

Description

The high reliability acquisition method of EEG signals
Technical field
The present invention relates to eeg signal acquisition technology, more particularly, to the high reliability collection side of a kind of EEG signals Method.
Background technology
EEG signals (EEG) is a kind of typical bioelectrical signals, is the overall of cerebral cortex cranial nerve cell electrical activity Reflection, wherein contains substantial amounts of physiology and pathological information, is one of the important physiological parameter of Clinical detection, is also cognitive section The important means of the area researches such as, brain-computer interface and Alertness.Owing to tradition electroencephalogramsignal signal collection equipment is the hugest, no Being easy to the in good time acquisition of EEG signals, therefore the research and development of wireless remote electroencephalogramsignal signal collection equipment are significant.
Although existing data acquisition scheme need not user be familiar with brain wave acquisition electrode arrange position, but its In transmission of wireless signals itself exist some hinder eeg signals gather reliabilities factors.Such as, CN201410166176.4 discloses a kind of brain wave acquisition transfer approach, including: gather and lead EEG signals more;Lead brain by described more The signal of telecommunication is converted into optical signal;Receive described optical signal and the described optical signal received is converted into first signal of telecommunication;By institute State first signal of telecommunication to be digitized processing to obtain second signal of telecommunication;Described second signal of telecommunication is transmitted to gathering main frame.To the greatest extent Manage it and can solve the problem that wireless data link is unstable to a certain extent, but turning due to photoelectricity/electro-optical signal Change the distortion causing primary signal.On the other hand, owing to the signal to noise ratio of EEG signals is the lowest, jam-to-signal valid data Amplitude bigger so that signal is fallen into oblivion by noise substantially, and separating difficulty is very big, and the noise related to does not comprises only head fortune The interference that dynamic, facial muscle movements causes, also includes interference that power-supply fluctuation causes etc..
Therefore, in the environment of brain electric transducer is wirelessly connected with data process end, improve as wide as possible The collection reliability of EEG signals and the signal to noise ratio of EEG signals, be this area always endeavour solve problem.
Summary of the invention
In order to improve the wireless reliability of brain wave wireless collection scheme, provide solid for accurately processing of eeg signal Basis and ensure reliably, the invention provides the high reliability acquisition method of a kind of EEG signals, including:
(1) multiple EEG signals sensor acquisition EEG signals is utilized;
(2) multiple programmable amplifier is set, each programmable amplifier described and each EEG signals sensor described Connect correspondingly, amplify the letter of each EEG signals sensor output with the amplification according to each programmable amplifier Number;
(3) multiple enumerator is set, described individual count device and described programmable amplifier one_to_one corresponding, individual count device Count value be fixed value and the sequence number of the corresponding programmable amplifier of this fixed value;
(4) wireless transmission unit is set, the outfan of described wireless transmission unit and each described programmable amplifier with And the outfan of individual count device is connected;
(5) described programmable amplifier is exported by described wireless transmission unit signal and with this programmable amplifier phase The count value of corresponding enumerator is wirelessly transmitted to EEG signals controller with the form of the first array;
(6) through the multiple working cycle started from the 0th moment T0, the duty of each EEG signals sensor is determined, And and then the amplification of each described programmable amplifier is set when the second moment T2, wherein 1 working cycle includes step Suddenly the operation of (5).
This step (6) farther includes:
(61) at the 0th moment T0, it is assumed that the amplification of each programmable amplifier is the set of the first amplification;
(62) after described 0th moment T0, through multiple working cycle, wherein 1 working cycle includes step (5) Operation, when arriving the first moment T1, EEG signals controller is stored in the 0th moment T0 and subsequent the plurality of work Each EEG signals sensor in initial EEG signals sensor array in cycle and auxiliary EEG signals sensor array Output output valve after the amplification of programmable amplifier corresponding thereto, and determine each brain telecommunications according to these output valves The duty of number sensor, then according to described EEG signals working sensor state, arranges and senses with each EEG signals The amplification of the programmable amplifier that device is corresponding is the set of the second amplification;
(63) the second moment T2 arrived after experiencing again multiple working cycle after the first moment T1, described EEG signals Controller, according to the work state information of EEG signals sensor, arranges the amplification of each described programmable amplifier, makes Constant within next one time period equal with T0 to T2, then repeat step (61)-(63), until receiving EEG signals Till gathering termination signal, wherein T2 > T1.
Further, described EEG signals sensor uses dry electrode sensor.
Further, described dry electrode sensor uses the ThinkGear AM chip of Neurosky company of the U.S..
Further, the amplification of described programmable amplifier is 0-99.
Further, communicated by Bluetooth chip between described wireless transmission unit and EEG signals controller.
Further, described step (5) farther includes: described wireless transmission unit can will be compiled described in each in t The signal of journey amplifier output and the count value of the enumerator corresponding with each programmable amplifier described are with N number of first number The form of group, and the first array of the signal of the described programmable amplifier output including non-zero is wirelessly transmitted to brain Electrical signal control.
Further, described 1 working cycle includes the operation of a step (5).
Further, 3-4 working cycle it is spaced between described first moment T1 and described 0th moment T0.
Further, described Bluetooth chip uses the BLUENRG-MS chip of TI company.
Further, described EEG signals working sensor state includes working properly and operation irregularity two states.
Further, when described EEG signals working sensor state is state working properly, arrange and each brain electricity The amplification of the programmable amplifier that signal transducer is corresponding is an amplification in the set of the first amplification; Otherwise it is set to 0.
The beneficial effect comprise that
(1) according to the auxiliary EEG signals sensor of present invention original creation, the EEG signals that combining wireless transmission unit sends, Can at a high speed, process the EEG signals that must process efficiently, wherein process according to the EEG signals reliability of independent research Algorithm, compares the various algorithms of the prior art directly processed including noise signal, it is possible to make EEG signals to be analyzed Signal to noise ratio improve 30%-40%;
(2) according to the EEG signals reliability algorithm of the present invention, it is possible to adaptively changing reduces the power consumption of Bluetooth chip, Make the data transmission credibility under communication be greatly improved, test (i.e. in prior art according to inventor In the case of and in the context of this application, respectively by gather stipulated number data after, analytical data for analyze α E.E.G and This mode of total degree of available data is drawn after the availability of β E.E.G) reliability that records averagely improves about 40%- 55%.
(3) which brain telecommunications is the EEG signals that can arrive based on user information and Real-time Collection, periodically differentiate Number sensor acquisition to EEG signals be useful signal;
(4) can feed back according to the result of EEG signals, thus adjust the EEG signals sending EEG signals The duty of sensor so that EEG Processing efficiency is able to significantly increase;
(5) work of the sensor gathering EEG signals can according to the real-time status of EEG signals, be changed adaptively State, so that the power consumption occurrence dynamics of the Bluetooth communication chip of transmission EEG signals changes, is conducive to reducing EEG signals Gather required power consumption, thus the working life of wireless transmission unit at user when improving eeg signal acquisition.
Accompanying drawing explanation
Fig. 1 shows the FB(flow block) of the high reliability acquisition method of the EEG signals according to the present invention.
Detailed description of the invention
As it is shown in figure 1, the high reliability acquisition method of a kind of EEG signals of the present invention, including:
(1) multiple EEG signals sensor acquisition EEG signals is utilized;Specifically, this step includes:
First, initial EEG signals sensor array is set: i × j described EEG signals sensor is arranged to i row × J row (such as, as normally used in prior art, for cover the sensor array of user head), wherein i and j Being the natural number more than 1, wherein j row EEG signals sensor represents that EEG signals sensor is arranged on along user head The EEG signals sensor being electrically connected to each other on the front of contouring to the direction at rear, multiple, i row represents along user The EEG signals sensor the most not electrically connected on the left of contouring head to the direction of right, multiple, every string brain electricity Signal transducer is linked together by signal bus and electrical bus each other;Those skilled in the art should know: On above-mentioned each " arrange ", distance between adjacent brain electric signal sensor also differs, unless the contouring head of user is close to partly Spherical.In the present invention, user represent the object of EEG signals to be collected, user head refer to user typically wear or Dress the region of dry electrode sensor, the such as region of head hair line.
Secondly, auxiliary EEG signals sensor array is set: measure the direction at front to the rear of user contouring head On, along longest distance L of user headmaxWith beeline Lmin;EEG signals described in i-th on jth row passes On sensor, towards the direction at center, the user crown, distance to bePosition, arrange auxiliary brain electricity Signal transducer, wherein corresponding with EEG signals sensor described in the i-th on described jth row described auxiliary EEG signals Sensor is also coupled on described signal bus, LjThe side at front to the rear along user contouring head it is listed in for jth Length upwards, " | | " represent the computing that takes absolute value,Represent and take integer value;
Each EEG signals in described initial EEG signals sensor array and auxiliary EEG signals sensor array passes Sensor is become to be suitable for user by shaping silica gel to be worn over the structure of head.
If the output of the EEG signals sensor being positioned at the i-th row jth row in described initial EEG signals sensor array Voltage is Vi,jT (), t represents the temporal information that collection relates to.
If the EEG signals sensor being positioned at the i-th row jth row in described initial EEG signals sensor array is corresponding The output voltage of auxiliary EEG signals sensor is Vi',j(t)。
(2) multiple programmable amplifier is set, each programmable amplifier described and each EEG signals sensor described Connect correspondingly, amplify the letter of each EEG signals sensor output with the amplification according to each programmable amplifier Number;In this step, for each in described initial EEG signals sensor array and auxiliary EEG signals sensor array EEG signals sensor arranges programmable amplifier.
(3) multiple enumerator is set, described individual count device and described programmable amplifier one_to_one corresponding, individual count device Count value be fixed value and the sequence number of the corresponding programmable amplifier of this fixed value;In this step, for described initially Each EEG signals sensor in EEG signals sensor array and auxiliary EEG signals sensor array arranges enumerator, To identify this EEG signals sensor in whole initial EEG signals sensor array and auxiliary EEG signals sensor array All EEG signals sensors in sequence number, this sequence number whole initial EEG signals sensor array and auxiliary EEG signals All EEG signals sensors in sensor array are unique value.For ease of describing, by initial EEG signals sensor array Total number of row midbrain electric signal sensor is denoted as i × j, described auxiliary EEG signals sensor array midbrain electric signal sensor Total number be denoted as i × j, the most described initial EEG signals sensor array and auxiliary EEG signals sensor array midbrain telecommunications Total number of number sensor is 2 × i × j;
(4) wireless transmission unit is set, the outfan of described wireless transmission unit and each described programmable amplifier with And the outfan of individual count device is connected;
(5) described programmable amplifier is exported by described wireless transmission unit signal and with this programmable amplifier phase The count value of corresponding enumerator is wirelessly transmitted to EEG signals controller with the form of the first array;Excellent according to the present invention Selecting embodiment, described programmable amplifier can include the programmable resistor of resistance and instrumentation amplifier, wherein resistance can The resistor of programming is opened or closed for the signal received according to described wireless transmission unit, thus correspondingly produces defeated The signal entering this programmable amplifier produces 0 times of amplification (i.e. this programmable amplifier outfan non-output signal) or produces basis The signal that described wireless transmission unit receives carries out the amplification of specified multiple.According to a preferred embodiment of the invention, described resistance It is worth programmable resistor and passes through digital circuit, then reconnect instrumentation amplifier by D/A converting circuit.
(6) through the multiple working cycle started from the 0th moment T0, the duty of each EEG signals sensor is determined, And and then the amplification of each described programmable amplifier is set when the second moment T2.
This step (6) preferably includes:
(61) at the 0th moment T0, it is assumed that the amplification of each programmable amplifier is the set of the first amplification, if The programmable amplifier that serial number kth EEG signals sensor correspondence is connected the first amplification in this set is Ak
(62) after described 0th moment T0, through multiple working cycle, wherein 1 working cycle includes step (5) Operation, when arriving the first moment T1, EEG signals controller is stored in the 0th moment T0 and subsequent the plurality of work Each EEG signals sensor in initial EEG signals sensor array in cycle and auxiliary EEG signals sensor array Output output valve after the amplification of programmable amplifier corresponding thereto, and determine each brain telecommunications according to these output valves The duty of number sensor, then according to described EEG signals working sensor state, arranges and senses with each EEG signals The amplification of the programmable amplifier that device is corresponding is the set of the second amplification, if serial number kth EEG signals passes The programmable amplifier that sensor correspondence is connected the second amplification in this set is A'k;This step specifically includes:
First, before the first moment T1, experience M the working cycle (such as, M=3) altogether after being located at the 0th moment T0, For the T working cycle after the 0th moment T0, wherein T is more than 1 and T < M, described initial EEG signals sensor array In the output voltage of EEG signals sensor being positioned at the i-th row jth row beDescribed initial EEG signals sensor array The output voltage of auxiliary EEG signals sensor corresponding to EEG signals sensor being positioned at the i-th row jth row in row is
Then, rule of thumb formulaWith Between relation, determine the duty of EEG signals sensor of the i-th row jth row;IfThen think what the i-th row jth arranged The duty of EEG signals sensor is state working properly;It is otherwise operation irregularity state, by the brain electricity of the i-th row jth row The amplification of the corresponding programmable amplifier of signal transducer is set to A'k, the hereafter work shape of this EEG signals sensor State determines that mode is: judge
(63) the second moment T2 (such as, P=6) arrived after experiencing again P working cycle after the first moment T1, institute State the EEG signals controller work state information according to EEG signals sensor, putting of each described programmable amplifier is set Big multiple, is allowed to constant within the next time period equal with T0 to T2, then repeats step (61)-(63), until receiving To eeg signal acquisition termination signal, wherein T2 > T1, and the positive integer that P is M times.Specifically, this step includes:
If before arriving T2, calculate the work shape of above-mentioned i-th row jth row EEG signals sensor every M working cycle State, if arrive the second moment T2, the number of times that duty is state working properly of the i-th row jth row EEG signals sensor WithBetween magnitude relationship, if the former is more than the latter, then the EEG signals sensor by the i-th row jth row is corresponding The amplification of programmable amplifier reverts to the amplification that the T0 moment stores;Otherwise, this EEG signals sensor is corresponding The amplification of programmable amplifier be set to 0;
During the above-mentioned amplification arranging programmable amplifier, EEG signals controller is to described wireless transmission unit Sending such second array, this second array includes that multipair data, every pair of data all include following two parts data:
(1) Part I data: EEG signals sensor number;
(2) Part II data: putting of the programmable amplifier that the EEG signals sensor corresponding with this numbering is corresponding Big multiple.
After described wireless transmission unit receives above-mentioned second array, respectively data are carried out as follows by each of which Process: according to wherein Part I data, arrange the EEG signals sensor corresponding with these Part I data corresponding can The amplification of programming amplifier is the Part II data in a pair described data.
Preferably, described EEG signals sensor uses dry electrode sensor.
Preferably, described dry electrode sensor uses the ThinkGear AM chip of Neurosky company of the U.S..
Preferably, the amplification of described programmable amplifier is 0-99.
Preferably, communicated by Bluetooth chip between described wireless transmission unit and EEG signals controller.
Preferably, described step (5) farther includes: described wireless transmission unit is described able to programme by each in t The signal of amplifier output and the count value of the enumerator corresponding with each programmable amplifier described are with N number of first array Form, and the first array of signal that the described programmable amplifier including non-zero exports is wirelessly transmitted to brain electricity Signal controller.
Preferably, described 1 working cycle includes the operation of a step (5).
3-4 working cycle it is spaced between described first moment T1 and described 0th moment T0.
Preferably, described Bluetooth chip uses the BLUENRG-MS chip of TI company.
Preferably, described EEG signals working sensor state includes working properly and operation irregularity two states.
Preferably, when described EEG signals working sensor state is state working properly, arrange and each brain telecommunications An amplification in the set that amplification is the first amplification of number programmable amplifier that sensor is corresponding;No Then it is set to 0.
The narration made for presently preferred embodiments of the present invention above is the purpose for illustrating, and is not intended to limit present invention essence Really for disclosed form, learn and make an amendment or change to be possible based on above teaching or from embodiments of the invention , embodiment is for explaining orally the principle of the present invention and allowing those skilled in the art utilize the present invention to exist with various embodiments Actual application is upper and selects and narration, and the technological thought attempt of the present invention is determined by claim and equalization thereof.

Claims (10)

1. a high reliability acquisition method for EEG signals, including:
(1) multiple EEG signals sensor acquisition EEG signals is utilized;
(2) arranging multiple programmable amplifier, each programmable amplifier described is with each EEG signals sensor described one by one Correspondingly connected, the signal of each EEG signals sensor output is amplified with the amplification according to each programmable amplifier;
(3) multiple enumerator is set, described individual count device and described programmable amplifier one_to_one corresponding, the meter of individual count device Numerical value is fixed value and the sequence number of the corresponding programmable amplifier of this fixed value;
(4) wireless transmission unit is set, the outfan of described wireless transmission unit and each described programmable amplifier and each The outfan of individual enumerator is connected;
(5) described programmable amplifier is exported by described wireless transmission unit signal and corresponding with this programmable amplifier The count value of enumerator be wirelessly transmitted to EEG signals controller with the form of the first array;
(6) through the multiple working cycle started from the 0th moment T0, determine the duty of each EEG signals sensor, go forward side by side And the amplification of each described programmable amplifier is set when the second moment T2.
The high reliability acquisition method of EEG signals the most according to claim 1, it is characterised in that described EEG signals passes Sensor uses dry electrode sensor.
The high reliability acquisition method of EEG signals the most according to claim 2, it is characterised in that described dry electrode sensing Device uses the ThinkGear AM chip of Neurosky company of the U.S..
The high reliability acquisition method of EEG signals the most according to claim 1, it is characterised in that described amplification able to programme The amplification of device is 0-99.
The high reliability acquisition method of EEG signals the most according to claim 1, it is characterised in that described in be wirelessly transferred list Communicated by Bluetooth chip between unit and EEG signals controller.
The high reliability acquisition method of EEG signals the most according to claim 1, it is characterised in that described step (5) is entered One step includes: signal that each described programmable amplifier is exported in t by described wireless transmission unit and with described respectively The count value of the enumerator that individual programmable amplifier is corresponding is with the form of N number of first array, and by the institute including non-zero First array of the signal stating programmable amplifier output is wirelessly transmitted to EEG signals controller.
The high reliability acquisition method of EEG signals the most according to claim 1, it is characterised in that described 1 work week Phase includes the operation of a step (5).
The high reliability acquisition method of EEG signals the most according to claim 1, it is characterised in that described Bluetooth chip is adopted With the BLUENRG-MS chip of TI company.
The high reliability acquisition method of EEG signals the most according to claim 1, it is characterised in that described EEG signals passes Sense device working state includes working properly and operation irregularity two states.
The high reliability acquisition method of EEG signals the most according to claim 9, it is characterised in that when described brain telecommunications When number working sensor state is state working properly, the programmable amplifier corresponding with each EEG signals sensor is set The set that amplification is the first amplification in an amplification;Otherwise it is set to 0.
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