CN106110120A - A kind of Chinese medicine composition treating depression - Google Patents

A kind of Chinese medicine composition treating depression Download PDF

Info

Publication number
CN106110120A
CN106110120A CN201610569148.6A CN201610569148A CN106110120A CN 106110120 A CN106110120 A CN 106110120A CN 201610569148 A CN201610569148 A CN 201610569148A CN 106110120 A CN106110120 A CN 106110120A
Authority
CN
China
Prior art keywords
parts
radix
herba
fructus
chinese medicine
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Withdrawn
Application number
CN201610569148.6A
Other languages
Chinese (zh)
Inventor
杜娜
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Priority to CN201610569148.6A priority Critical patent/CN106110120A/en
Publication of CN106110120A publication Critical patent/CN106110120A/en
Withdrawn legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/904Stemonaceae (Stemona family), e.g. croomia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K33/00Medicinal preparations containing inorganic active ingredients
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/618Molluscs, e.g. fresh-water molluscs, oysters, clams, squids, octopus, cuttlefish, snails or slugs
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/56Materials from animals other than mammals
    • A61K35/63Arthropods
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/232Angelica
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/23Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
    • A61K36/234Cnidium (snowparsley)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/24Apocynaceae (Dogbane family), e.g. plumeria or periwinkle
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/282Artemisia, e.g. wormwood or sagebrush
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • A61K36/288Taraxacum (dandelion)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/31Brassicaceae or Cruciferae (Mustard family), e.g. broccoli, cabbage or kohlrabi
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/42Cucurbitaceae (Cucumber family)
    • A61K36/428Trichosanthes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/53Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/532Agastache, e.g. giant hyssop
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/56Loganiaceae (Logania family), e.g. trumpetflower or pinkroot
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/63Oleaceae (Olive family), e.g. jasmine, lilac or ash tree
    • A61K36/634Forsythia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/65Paeoniaceae (Peony family), e.g. Chinese peony
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/70Polygonaceae (Buckwheat family), e.g. spineflower or dock
    • A61K36/704Polygonum, e.g. knotweed
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/71Ranunculaceae (Buttercup family), e.g. larkspur, hepatica, hydrastis, columbine or goldenseal
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/734Crataegus (hawthorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/74Rubiaceae (Madder family)
    • A61K36/746Morinda
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/75Rutaceae (Rue family)
    • A61K36/756Phellodendron, e.g. corktree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/89Cyperaceae (Sedge family)
    • A61K36/8905Cyperus (flatsedge)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/898Orchidaceae (Orchid family)

Landscapes

  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Marine Sciences & Fisheries (AREA)
  • Zoology (AREA)
  • Insects & Arthropods (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a kind of Chinese medicine composition treating depression, belong to technical field of Chinese medicines.Solve the defect that existing medicine easily recurs.By Cortex Phellodendri 15 parts, Flos Buddlejae 38 parts, Pseudobulbus Cremastrae Seu Pleiones 38 parts, Caulis Trachelospermi 25 parts, Herba Taxilli 5 10 parts, Radix Morindae Officinalis 6 10 parts, Rhizoma Cyperi 10 15 parts, Aspongopus 5 10 parts, Herba Artemisiae Anomalae 15 parts, Semen Sinapis Albae 10 15 parts, Pumex 38 parts, the Radix Stemonae 13 parts, Concha Margaritifera 5 10 parts, Flos Albiziae 8 12 parts, Caulis Polygoni Multiflori 10 15 parts, Styrax 6 10 parts, the Radix Paeoniae Alba 48 parts, Radix Angelicae Sinensis 58 parts, Fructus Cnidii 13 parts, Semen Trigonellae 38 parts, Radix Trichosanthis 13 parts, Medulla Junci 13 parts, 38 parts of Seem Lablab Album, Flos Rosae Chinensis 6 10 parts, Herba Pogostemonis 5 10 parts, Herba Taraxaci 8 12 parts, Fructus Crataegi 6 10 parts, Fructus Forsythiae 6 10 parts, Fructus Lycii 15 parts composition.The present invention is suitable for patients with depression and takes.

Description

A kind of Chinese medicine composition treating depression
Technical field
The present invention relates to a kind of Chinese medicine composition treating depression, belong to technical field of Chinese medicines.
Background technology
Depression is referred to as " blue secret worry " in west, is a kind of common mental sickness, mainly shows as depressed, Interest lowers, pessimistic, retardation of thinking, lacks initiative, and self-accusation is from crime, and diet, sleep are poor, worry oneself suffer from various disease, Feeling that whole body many places are uncomfortable, severe patient may occur in which suicidal thought and behavior.Depression seriously perplexs the live and work of patient, gives Family and society bring white elephant, and the patients with depression of about 15% dies from suicide.
Western medical treatment depression not only cost is high, and the course for the treatment of is long, and side effect is big.The traditional Chinese medical science thinks the Etiological of depression Become homeless foster for the liver failing to maintain the normal flow of QI, dysfunction of the spleen in transportation, the heart, although liver, spleen, three internal organs of the heart all have relevant, but emphasize particularly on different fields.Depression of liver-QI Many with gas, blood, fire relevant, and eat, wet, expectorant prevailing relationship in spleen, the heart then more shows as deficiency syndrome, as lack of preservation of spirit, deficiency of heart-blood, The heart-yin virtual loss etc., also have some to belong to vital QI being weakened and pathogen being violent, the syndrome of simulataneous insufficiency and excessive.Depression is the most sick at gas, prolonged illness and blood, therefore the stagnation of QI The syndrome of blood stasis is the most common, and depression is not healed, and often undermines spleen, kidney, causes that yang-energy is depressed, mental deterioration Syndrome.
Summary of the invention
It is an object of the invention to provide a kind of Chinese medicine composition treating depression, short treating period, determined curative effect.
The Chinese medicine composition of described treatment depression, is made up of the raw material of Chinese medicine of following weight portion:
Cortex Phellodendri 1-5 part, Flos Buddlejae 3-8 part, Pseudobulbus Cremastrae Seu Pleiones 3-8 part, Caulis Trachelospermi 2-5 part, Herba Taxilli 5-10 part, Radix Morindae Officinalis 6-10 Part, Rhizoma Cyperi 10-15 part, Aspongopus 5-10 part, Herba Artemisiae Anomalae 1-5 part, Semen Sinapis Albae 10-15 part, Pumex 3-8 part, Radix Stemonae 1-3 part, Concha Margaritifera 5-10 part, Flos Albiziae 8-12 part, Caulis Polygoni Multiflori 10-15 part, Styrax 6-10 part, Radix Paeoniae Alba 4-8 part, Radix Angelicae Sinensis 5-8 part, cnidium monnieri Sub-1-3 part, Semen Trigonellae 3-8 part, Radix Trichosanthis 1-3 part, Medulla Junci 1-3 part, Seem Lablab Album 3-8 part, Flos Rosae Chinensis 6-10 part, Herba Pogostemonis 5-10 Part, Herba Taraxaci 8-12 part, Fructus Crataegi 6-10 part, Fructus Forsythiae 6-10 part, Fructus Lycii 1-5 part.
Preferably treat the Chinese medicine composition of depression, be made up of the raw material of Chinese medicine of following weight portion:
Cortex Phellodendri 3 parts, Flos Buddlejae 5 parts, Pseudobulbus Cremastrae Seu Pleiones 5 parts, Caulis Trachelospermi 3 parts, Herba Taxilli 8 parts, Radix Morindae Officinalis 8 parts, Rhizoma Cyperi 12 parts, nine Fragrant worm 7 parts, Herba Artemisiae Anomalae 3 parts, Semen Sinapis Albae 12 parts, Pumex 5 parts, the Radix Stemonae 2 parts, Concha Margaritifera 7 parts, Flos Albiziae 10 parts, Caulis Polygoni Multiflori 12 Part, Styrax 8 parts, the Radix Paeoniae Alba 6 parts, Radix Angelicae Sinensis 6 parts, Fructus Cnidii 2 parts, Semen Trigonellae 5 parts, Radix Trichosanthis 2 parts, Medulla Junci 2 parts, 5 parts of Seem Lablab Album, Flos Rosae Chinensis 8 parts, Herba Pogostemonis 8 parts, Herba Taraxaci 10 parts, Fructus Crataegi 8 parts, Fructus Forsythiae 8 parts, Fructus Lycii 3 parts.
Each Mechanism of TCM:
Cortex Phellodendri: bitter, cold.Return kidney, bladder warp.Function with cure mainly: heat clearing and damp drying, pathogenic fire purging except steam, detoxification sore treatment.For damp and hot Dysentery, jaundice dark coloured urine, leukorrhagia pudendal pruritus, the puckery pain of pyretic stranguria, tinea pedis flaccidity is preesed, hectic fever due to YIN-deficiency consumptive fever, night sweat, and seminal emission, sore swollen toxin, eczema is wet Skin ulcer.
Flos Buddlejae: sweet, is slightly cold.Return Liver Channel.Function with cure mainly: clearing away heat-fire, nourishing the liver to improve visual acuity, nebula removing.For conjunctival congestion and swelling pain, Many tear photophobia, the raw nebula film of mesh, hepatasthenia dim eyesight, blurring of vision.
Pseudobulbus Cremastrae Seu Pleiones: sweet, micro-pungent is cool.Return liver, spleen channel.Function with cure mainly: heat-clearing and toxic substances removing, dissipating phlegm and resolving masses.For carbuncle furuncle Poison, scrofula sucutaneous nodule, snake bite and insect sting, lame abdominal mass mass in the abdomen.
Caulis Trachelospermi: bitter, is slightly cold.GUIXIN, liver, kidney channel.Function with cure mainly: dispelling wind and removing obstruction in the collateral, removing heat from blood subside a swelling.For rheumatic fever Numbness, muscle arteries and veins contracture, soreness of waist and knee joint, sore throat, injury from falling down.
Herba Taxilli: bitter, sweet, flat.Return liver, kidney channel.Function with cure mainly: wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, antiabortive unit.For Rheumatic arthralgia, soreness of the waist and knees, muscles and bones is unable, metrorrhagia through many, blood leaking in gestation, frequent fetal movement, have a dizzy spell.
Radix Morindae Officinalis: sweet, pungent, tepor.Return kidney, Liver Channel.Function with cure mainly: kidney-replenishing, bone and muscle strengthening, wind-damp dispelling.For sexual impotence Seminal emission, cold womb is infertile, menoxenia, and few abdomen cold type of pain, rheumatic arthralgia, muscles and bones flaccidity is soft.
Rhizoma Cyperi: hardship pungent, micro-, micro-sweet, flat.Return liver, spleen, tri-jiao channel.Function with cure mainly: dispersing the stagnated live-QI to relieve the stagnation of QI, regulating the flow of QI to ease the stomach, regulating menstruation Pain relieving.For stagnation of QI due to depression of the liver, distending pain in the chest and hypochondrium, hernia pain, distending pain of the breast, stagnation of QI in spleen and stomach, gastral cavity abdomen painful abdominal mass is vexed, distension pain, menstruation Uncomfortable, amenorrhea dysmenorrhea.
Aspongopus: salty, temperature.Return liver,spleen,kidney warp.Function with cure mainly: regulating QI to relieve pain, warming middle-JIAO is supporing yang.For cold syndrome of the stomach distending pain, Stomachache due to hyperactive liver-QI attacking the stomach, impotence due to deficiency of the kidney, soreness of waist and knee joint.
Herba Artemisiae Anomalae: bitter, temperature.Enter the heart, spleen channel.Function cures mainly: removing blood stasis stimulates the menstrual flow, healing up sore and subduing swelling.Controlling amenorrhea lump in the abdomen, chest and abdomen are swollen Bitterly, puerperal blood stasis, traumatic injury, incised wound is hemorrhage, carbuncle poison swell.
Semen Sinapis Albae: pungent, temperature.Enter lung, stomach warp.Function cures mainly: promoting the circulation of QI eliminating phlegm, warming stomach for dispelling cold, removing obstruction in the collateral to relieve pain, mass dissipating and swelling eliminating.
Pumex: salty, cold.Function cures mainly: removing heat from the lung and dissipating phlegm, hard masses softening and resolving.For cough due to lung-heat, yellowish thick sputum, spitting of blood, prop up Tracheitis, tuberculous lymphadenitis.
The Radix Stemonae: sweet, bitter, tepor.Return lung meridian.Function with cure mainly: nourishing the lung to keep the adverse QI downward cough-relieving, parasite killing delousing.Cough for new chronic cough, Pulmonary tuberculosis cough, pertussis;Outer for head louse, body louse, enterobiasis, pudendal pruritus.Honey Radix Stemonae nourishing the lung to arrest cough.For deficiency of YIN chronic cough.
Concha Margaritifera: salty, cold.Return liver, heart channel.Function with cure mainly: suppressing the hyperactive liver and subsiding YANG, arresting convulsion of calming the nerves, improving acuity of vision and removing nebula.For having a headache Dizziness, palpitation with fear insomnia, cataract, blurring of vision.
Flos Albiziae: sweet, bitter, flat.Function cures mainly: merit is in resolving depression of regulating the flow of vital energy, tranquilizing by nourishing the heart, and network pain relieving.Control depression of liver-QI, breast Vexed, hypochondriac pain, heart peratodynia, forgetful, insomnia, traumatic injury pain.
Caulis Polygoni Multiflori: sweet micro-hardship is flat.It is included into the heart, Liver Channel.Function cures mainly: nourish heart, and calms the nerves, and dredging collateral dispels the wind.Control insomnia, labor Wound, hyperhidrosis, blood deficiency general pain, carbuncle, scrofula, wind skin ulcer scabies.
Styrax: pungent, temperature.GUIXIN, spleen channel.Function with cure mainly: have one's ideas straightened out, ward off dirty, pain relieving.For apoplexy syncope due to accumulation of phlegm, suddenly dusk Fall, obstruction of qi in the chest and cardialgia, chest and abdomen cold type of pain, infantile convulsion.
The Radix Paeoniae Alba: bitter, sour, is slightly cold.Return liver, spleen channel.Function with cure mainly: nourishing blood for regulating menstruation, astringing YIN to stop sweating, easing the affected liver to relieve pain, stabilize Liver-yang.For blood deficiency and yellow complexion, menoxenia, spontaneous perspiration, night sweat, hypochondriac pain, stomachache, limb pain twin, dizziness of having a headache.
Radix Angelicae Sinensis: sweet, acrid, warm.Return liver, the heart, spleen channel.Function with cure mainly: replenishing and activating blood, menstruction regulating and pain relieving, loosening bowel to relieve constipation.For Blood deficiency and yellow complexion, dizziness cardiopalmus, menoxenia, amenorrhea dysmenorrhea, asthenia cold abdominalgia, rheumatic arthralgia, injury from falling down, ulcer sores, dryness of the intestine Constipation.
Fructus Cnidii: pungent, bitter, temperature;Slightly poisonous.Return kidney channel.Function with cure mainly: dampness is dispeled the wind, killing parasites for relieving itching, warming the kidney to invigorate YANG. For pudendal pruritus leukorrhagia, eczema pruritus, arthralgia chiefly caused by damp pathogen lumbago, impotence due to deficiency of the kidney, cold womb is infertile.
Semen Trigonellae: warm in nature, bitter in the mouth.Function cures mainly: the kidney warming, cold relieving, pain relieving.For kidney cold caused by deficiency, cold and pain in the lower abdomen, hernia Gas, the disturbance of lower legs due to pathogenic cold and dampness.
Radix Trichosanthis: hardship sweet, micro-, is slightly cold.Attach to the lung and stomach meridians.Function with cure mainly: clearing away heat-fire, promoting the production of body fluid to quench thirst, detumescence and apocenosis. For calentura excessive thirst, lung-heat type cough, interior-heat quenches one's thirst, sore swollen toxin.
Medulla Junci: sweet, light, is slightly cold.GUIXIN, lung, small intestine meridian.Function with cure mainly: clearing away heart-fire, diuresis.For vexed mistake Sleep, the puckery pain of oliguria, aphtha of the mouth and tongue.
Seem Lablab Album: sweet is flat.Enter spleen, stomach warp.Function cures mainly: spleen invigorating and in, removing dampness of relieving summer heat.Control heat-damp in summer to vomit and diarrhoea, insufficiency of the spleen vomiting, Lack of appetite chronic diarrhea, water retention quenches one's thirst, leucorrhea with red and white discharge, infantile malnutrition.
Flos Rosae Chinensis: sweet, temperature.Return Liver Channel.Function with cure mainly: promoting blood flow to regulate menstruation, dispersing the stagnated live-QI to relieve the stagnation of QI.For qi depression to blood stasis, menstruation is not Adjust, dysmenorrhea, amenorrhea, distending pain in the chest and hypochondrium.
Herba Pogostemonis: slightly warm in nature, acrid in the mouth.Dispelling summer-heat from superficies of the body, removing dampness to restore normal function of the stomach.For summer-heat damp cold, uncomfortable in chest, stomachache vomiting and diarrhoea.
Herba Taraxaci: bitter, dry, cold.Return liver, stomach warp.Function with cure mainly: heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, inducing diuresis for treating stranguria syndrome.For Furuncle swelling toxin, acute mastitis, scrofula, conjunctival congestion, pharyngalgia, lung abscess, acute appendicitis, jaundice due to damp-heat, the puckery pain of pyretic stranguria.
Fructus Crataegi: sour, sweet, tepor.Return spleen, stomach, Liver Channel.Function with cure mainly: promoting digestion and invigorating the stomach, circulation of qi promoting dissipating blood stasis, change turbid blood fat reducing.With In meat stagnation, gastral cavilty distension, dysentery stomachache, blood stasis amenorrhea, postpartum stagnation, trusted subordinate's twinge, obstruction of qi in the chest and cardialgia, hernia pain, height Lipidemia.Fructus Crataegi (parched to brown) dyspepsia and intestinal stasis relieving effect strengthens.For meat stagnation, dysentery is not well.
Fructus Forsythiae: cold nature, bitter in the mouth.Heat-clearing and toxic substances removing, dispersing swelling and dissipating binds, dispelling wind and heat pathogens.For carbuncle, scrofula, acute mastitis, erysipelas, Anemopyretic cold, epidemic febrile disease from the beginning of, warm is joined the army, high hot excessive thirst, and coma sends out speckle, the puckery pain of pyretic stranguria.
Fructus Lycii: sweet is flat.Return liver, kidney channel.Function with cure mainly: nourishing the liver and kidney, replenishing vital essence to improve eyesight.For asthenia damage of essence, waist knee joint Aching, vertigo and tinnitus, impotence and seminal emission, interior-heat quenches one's thirst, blood deficiency and yellow complexion, and blurred vision is failed to understand.
Compared with prior art the invention has the beneficial effects as follows:
The present invention is based on theory of Chinese medical science, and compatibility science, medication is reasonable, uses safe without toxic side effect, and all medicines share Have depressed liver-energy dispersing and QI regulating, tonifying speen and tonifying kidney, promoting QI circulation for relieving depression, tranquilizing by nourishing the heart, blood circulation promoting and blood stasis dispelling, warming for resolving cold-phlegm, benefiting qi and nourishing blood, dredge the meridian passage, Effects such as Yin-nourishing and Yang-supporting, it is possible to cure fast and effectively due to pressing down that the liver failing to maintain the normal flow of QI, dysfunction of the spleen in transportation, the heart become homeless that the reason such as foster causes Strongly fragrant disease, low cost of the present invention, painful little, short treating period, good effect, cure rate height.
Below in conjunction with clinical trial and model case, the invention will be further described.
One, clinical trial:
1, clinical data:
Randomly select patients with depression 100 example, wherein male 54, women 46, the age between 16 to 76 years old, generally Lab testing can have urine (serotonin) to send minimizing and cerebrospinal fluid serotonin content to lower, but needs clinically to get rid of because of brain Inflammation, the cerebral tumor, cerebrovascular, the depressive emotion that parkinson disease are occurred together;Need to get rid of the depressed feelings that physical disease is occurred together simultaneously Thread, such as hypothyroidism, chronic hepatitis, systemic lupus erythematosus (sle) etc..It is slow that cardinal symptom shows as hypothymergasia, thinking Slow, speech action reduces, slow, sentimentality, pessimistic and worldweary, be in a very depressed state shakiness, and mood is irritated, sigh in despair, enterprise of committing suiside Figure, insomnia forgetfulness, interest blank, palpitation and being susceptible to fright, susceptible to sorrow is easily cried.
2, Therapeutic Method:
Chinese medicine composition potion every day of the present invention, is decocted in water for oral dose, point twice one after each meal, 5 days 1 courses for the treatment of, general medication 4 sooner or later The individual course for the treatment of.
3, criterion of therapeutical effect:
Recovery from illness: every inspection all shows normally, simultaneous phenomenon disappears;
Effective: every inspection all tends to normal, and simultaneous phenomenon alleviates;
Invalid: each clinical symptoms is without improving.
4, therapeutic outcome:
100 example patients with depression, after 4 courses for the treatment of of taking medicine, 95 people's recoveries from illness, 4 people are effective, and 1 people is invalid, total cure rate 95%, total effective rate 99%, follow up a case by regular visits to 1 year without patients with recurrent.
Model case:
Feng, man, 42 years old, suffer from depression for many years, hypothymergasia when coming to go to a doctor, retardation of thinking, love are stayed alone, how anxious kind Sense, pessimistic and worldweary, sigh in despair, insomnia forgetfulness, once to do various treatment, took a turn for the better when being all treatment, a period of time recurs again, makes With 2 courses for the treatment of of Chinese medicine composition of the present invention, the symptom such as depressed, insomnia forgetfulness, sigh in despair is clearly better, medication four treatment Journey, every inspection all shows normally, and simultaneous phenomenon disappears, and follows up a case by regular visits to 3 years without recurrence.
Shut out certain, female, 54 years old, suffer from depression for many years, when coming to go to a doctor, language motion is slow, emotional instability, insomnia forgetfulness, Palpitation and being susceptible to fright, susceptible to sorrow is easily cried, and once did various treatment, and took a turn for the better when being all treatment, and a period of time recurs again, uses Chinese medicine of the present invention 2 courses for the treatment of of compositions, being emotionally stable, love speaking and laughing, four courses for the treatment of of medication, every inspection all shows that normally simultaneous phenomenon disappears Lose, follow up a case by regular visits to 3 years without recurrence.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention will be further described.
Embodiment 1
The Chinese medicine composition of described treatment depression, is made up of the raw material of Chinese medicine of following weight portion:
Cortex Phellodendri 1 part, Flos Buddlejae 3 parts, Pseudobulbus Cremastrae Seu Pleiones 3 parts, Caulis Trachelospermi 2 parts, Herba Taxilli 5 parts, Radix Morindae Officinalis 6 parts, Rhizoma Cyperi 10 parts, nine Fragrant worm 5 parts, Herba Artemisiae Anomalae 1 part, Semen Sinapis Albae 10 parts, Pumex 3 parts, the Radix Stemonae 1 part, Concha Margaritifera 5 parts, Flos Albiziae 8 parts, Caulis Polygoni Multiflori 10 Part, Styrax 6 parts, the Radix Paeoniae Alba 4 parts, Radix Angelicae Sinensis 5 parts, Fructus Cnidii 1 part, Semen Trigonellae 3 parts, Radix Trichosanthis 1 part, Medulla Junci 1 part, 3 parts of Seem Lablab Album, Flos Rosae Chinensis 6 parts, Herba Pogostemonis 5 parts, Herba Taraxaci 8 parts, Fructus Crataegi 6 parts, Fructus Forsythiae 6 parts, Fructus Lycii 1 part.
Embodiment 2
The Chinese medicine composition of described treatment depression, is made up of the raw material of Chinese medicine of following weight portion:
Cortex Phellodendri 3 parts, Flos Buddlejae 5 parts, Pseudobulbus Cremastrae Seu Pleiones 5 parts, Caulis Trachelospermi 3 parts, Herba Taxilli 8 parts, Radix Morindae Officinalis 8 parts, Rhizoma Cyperi 12 parts, nine Fragrant worm 7 parts, Herba Artemisiae Anomalae 3 parts, Semen Sinapis Albae 12 parts, Pumex 5 parts, the Radix Stemonae 2 parts, Concha Margaritifera 7 parts, Flos Albiziae 10 parts, Caulis Polygoni Multiflori 12 Part, Styrax 8 parts, the Radix Paeoniae Alba 6 parts, Radix Angelicae Sinensis 6 parts, Fructus Cnidii 2 parts, Semen Trigonellae 5 parts, Radix Trichosanthis 2 parts, Medulla Junci 2 parts, 5 parts of Seem Lablab Album, Flos Rosae Chinensis 8 parts, Herba Pogostemonis 8 parts, Herba Taraxaci 10 parts, Fructus Crataegi 8 parts, Fructus Forsythiae 8 parts, Fructus Lycii 3 parts.
Embodiment 3
The Chinese medicine composition of described treatment depression, is made up of the raw material of Chinese medicine of following weight portion:
Cortex Phellodendri 5 parts, Flos Buddlejae 8 parts, Pseudobulbus Cremastrae Seu Pleiones 8 parts, Caulis Trachelospermi 5 parts, Herba Taxilli 10 parts, Radix Morindae Officinalis 10 parts, Rhizoma Cyperi 15 parts, Aspongopus 10 parts, Herba Artemisiae Anomalae 5 parts, Semen Sinapis Albae 15 parts, Pumex 8 parts, the Radix Stemonae 3 parts, Concha Margaritifera 10 parts, Flos Albiziae 12 parts, Polygonm multiflorum Thunb 15 parts of rattan, Styrax 10 parts, the Radix Paeoniae Alba 8 parts, Radix Angelicae Sinensis 8 parts, Fructus Cnidii 3 parts, Semen Trigonellae 8 parts, Radix Trichosanthis 3 parts, Medulla Junci 3 parts, flat Bean 8 parts, Chinese rose 10 parts, Herba Pogostemonis 10 parts, Herba Taraxaci 12 parts, Fructus Crataegi 10 parts, Fructus Forsythiae 10 parts, Fructus Lycii 5 parts.

Claims (2)

1. the Chinese medicine composition treating depression, it is characterised in that be made up of the raw material of Chinese medicine of following weight portion:
Cortex Phellodendri 1-5 part, Flos Buddlejae 3-8 part, Pseudobulbus Cremastrae Seu Pleiones 3-8 part, Caulis Trachelospermi 2-5 part, Herba Taxilli 5-10 part, Radix Morindae Officinalis 6-10 part, Rhizoma Cyperi 10-15 part, Aspongopus 5-10 part, Herba Artemisiae Anomalae 1-5 part, Semen Sinapis Albae 10-15 part, Pumex 3-8 part, Radix Stemonae 1-3 part, Margarita Female 5-10 part, Flos Albiziae 8-12 part, Caulis Polygoni Multiflori 10-15 part, Styrax 6-10 part, Radix Paeoniae Alba 4-8 part, Radix Angelicae Sinensis 5-8 part, Fructus Cnidii 1- 3 parts, Semen Trigonellae 3-8 part, Radix Trichosanthis 1-3 part, Medulla Junci 1-3 part, Seem Lablab Album 3-8 part, Flos Rosae Chinensis 6-10 part, Herba Pogostemonis 5-10 part, Pu Herba Taraxaci 8-12 part, Fructus Crataegi 6-10 part, Fructus Forsythiae 6-10 part, Fructus Lycii 1-5 part.
The Chinese medicine composition for the treatment of depression the most according to claim 1, it is characterised in that by the Chinese medicine of following weight portion Raw material forms:
Cortex Phellodendri 3 parts, Flos Buddlejae 5 parts, Pseudobulbus Cremastrae Seu Pleiones 5 parts, Caulis Trachelospermi 3 parts, Herba Taxilli 8 parts, Radix Morindae Officinalis 8 parts, Rhizoma Cyperi 12 parts, Aspongopus 7 parts, Herba Artemisiae Anomalae 3 parts, Semen Sinapis Albae 12 parts, Pumex 5 parts, the Radix Stemonae 2 parts, Concha Margaritifera 7 parts, Flos Albiziae 10 parts, Caulis Polygoni Multiflori 12 parts, Soviet Union Blending 8 parts, the Radix Paeoniae Alba 6 parts, Radix Angelicae Sinensis 6 parts, Fructus Cnidii 2 parts, Semen Trigonellae 5 parts, Radix Trichosanthis 2 parts, Medulla Junci 2 parts, 5 parts of Seem Lablab Album, Chinese rose Spend 8 parts, Herba Pogostemonis 8 parts, Herba Taraxaci 10 parts, Fructus Crataegi 8 parts, Fructus Forsythiae 8 parts, Fructus Lycii 3 parts.
CN201610569148.6A 2016-07-19 2016-07-19 A kind of Chinese medicine composition treating depression Withdrawn CN106110120A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
CN201610569148.6A CN106110120A (en) 2016-07-19 2016-07-19 A kind of Chinese medicine composition treating depression

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CN201610569148.6A CN106110120A (en) 2016-07-19 2016-07-19 A kind of Chinese medicine composition treating depression

Publications (1)

Publication Number Publication Date
CN106110120A true CN106110120A (en) 2016-11-16

Family

ID=57288946

Family Applications (1)

Application Number Title Priority Date Filing Date
CN201610569148.6A Withdrawn CN106110120A (en) 2016-07-19 2016-07-19 A kind of Chinese medicine composition treating depression

Country Status (1)

Country Link
CN (1) CN106110120A (en)

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106975008A (en) * 2017-03-02 2017-07-25 青岛市妇女儿童医院 A kind of Chinese medicine composition for being used to treat child depression

Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1994451A (en) * 2006-12-27 2007-07-11 河南太龙药业股份有限公司 Chinese medicinal composition for treating depression, its preparation method and application
CN101085231A (en) * 2007-06-20 2007-12-12 济南新境界企业管理咨询有限公司 Internal-applied traditional Chinese medicine composition for treating depression
CN104225450A (en) * 2013-06-24 2014-12-24 山东明仁福瑞达制药股份有限公司 Traditional Chinese medicine for treating depression

Patent Citations (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1994451A (en) * 2006-12-27 2007-07-11 河南太龙药业股份有限公司 Chinese medicinal composition for treating depression, its preparation method and application
CN101085231A (en) * 2007-06-20 2007-12-12 济南新境界企业管理咨询有限公司 Internal-applied traditional Chinese medicine composition for treating depression
CN104225450A (en) * 2013-06-24 2014-12-24 山东明仁福瑞达制药股份有限公司 Traditional Chinese medicine for treating depression

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106975008A (en) * 2017-03-02 2017-07-25 青岛市妇女儿童医院 A kind of Chinese medicine composition for being used to treat child depression

Similar Documents

Publication Publication Date Title
CN103816254A (en) Chinese herba preparation for treating anemofrigid-damp arthralgia and muscle and bone strain and application method of Chinese herba preparation
CN105816617A (en) Traditional Chinese medicine composition for treating obesity type polycystic ovarian syndrome
CN105288191A (en) Medicinal moxa stick for treating breast lumps
CN100548352C (en) A kind of Chinese medicine composition of orally taken for curing depression
CN107095905A (en) A kind of healthful moxibustion bar and moxibustion cream
CN106266999A (en) A kind of Chinese medicine composition treating irritability and palpitation and insomnia and preparation method thereof
CN104257778B (en) A kind of Chinese medicine treating rheumatic arthritis
CN103393825B (en) Traditional Chinese medicine for treating catatonic headache and preparation method thereof
CN104721758A (en) Pharmaceutical for treating ovarian cyst and preparing method thereof
CN104524462A (en) Traditional Chinese medicine formula for treating craniocerebral injury or intracranial tumour postoperative vertigo
CN108272986A (en) A kind of draft is bathed powder
CN107537015A (en) It is a kind of treat rheumatism fever and chills caused by numbness disease pill medicine and preparation method
CN106110120A (en) A kind of Chinese medicine composition treating depression
CN105999117A (en) Preparation of traditional Chinese medicine plaster applied to meridian blistering cupping detoxification and using method of traditional Chinese medicine plaster
CN104547553A (en) Traditional Chinese medicine for treating nervous endocrine disorder
CN104367827A (en) Traditional Chinese medicine for treating spleen-qi deficiency-weakness syndrome type somnolence
CN104162139A (en) Traditional Chinese medicine capsule and matched hot paste for treating secondary hypothyroidism
CN106214831A (en) One treats leukodermic Chinese medicine for oral administration ball and preparation method thereof
CN106215165A (en) A kind of Chinese medicine composition for treating wind and cold type of blood-stasis obstructing in the interior scapulohumeral periarthritis
CN105456955A (en) Medicine preparation for treating depressive disorder and application thereof
CN106166233A (en) A kind of Chinese medicine composition treating endocrine disturbance
CN106214870A (en) A kind of lavipeditum powder treating rheumatic arthritis and preparation method thereof
CN105878497A (en) Medicinal moxa stick capable of treating insomnia
CN105311562A (en) Traditional Chinese medicine for calming livers and reducing blood pressures
CN105288549A (en) Medicinal moxa stick for treating breast lumps

Legal Events

Date Code Title Description
C06 Publication
PB01 Publication
C10 Entry into substantive examination
SE01 Entry into force of request for substantive examination
WW01 Invention patent application withdrawn after publication
WW01 Invention patent application withdrawn after publication

Application publication date: 20161116