CN106109760A - For treating the medicine of prolapse of lumbar intervertebral disc - Google Patents

For treating the medicine of prolapse of lumbar intervertebral disc Download PDF

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CN106109760A
CN106109760A CN201610673578.2A CN201610673578A CN106109760A CN 106109760 A CN106109760 A CN 106109760A CN 201610673578 A CN201610673578 A CN 201610673578A CN 106109760 A CN106109760 A CN 106109760A
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radix
intervertebral disc
lumbar intervertebral
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黄琴
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Abstract

The invention discloses a kind of medicine for treating prolapse of lumbar intervertebral disc, be made up of the raw material of following weight parts proportioning: eupolyphoge sinensis 5 15 parts, Scorpio 5 15 parts, Zaocys 5 15 parts, 12 24 parts of Flos Carthami, Radix Angelicae Pubescentis 8 15 parts, Radix Saposhnikoviae 5 15 parts, Rhizoma Curculiginis 12 18 parts, the Cortex Eucommiae 8 15 parts, Radix Morindae Officinalis 15 20 parts, Squama Manis 5 15 parts, Pheretima 18 25 parts, Radix Aconiti Kusnezoffii 8 15 parts, Semen Strychni 8 18 parts, Radix Notoginseng 15 25 parts.The present invention treats the medicine that chronic lumbar vertebrae intercalated disc is prominent, choose 14 kinds of natural Chinese medicine scientific compatibility, formula is simple, and each crude drug synergism plays blood circulation promoting and blood stasis dispelling, the effect of reducing swelling and alleviating pain, instant effect, treating both the principal and secondary aspects of a disease, has no side effect, and its preparation method is simple, taking convenience, low cost, effective percentage reaches more than 96%.

Description

For treating the medicine of prolapse of lumbar intervertebral disc
Technical field
The present invention relates to Chinese medicine, a kind of medicine for treating prolapse of lumbar intervertebral disc.
Background technology
Prolapse of lumbar intervertebral disc is one of the most common illness of Orthopaedics Clinic, is also the most common reason of lumbago and skelalgia. Review history, just describe the outward appearance of intervertebral disc as far back as Vesalius in 1543.The twenties in 20th century, the Shmorl of Germany is successively Deliver 11 relevant intervertebral disc to dissect and the article of pathology, intervertebral disc has been done wide research.1932, Barr was first Proposition prolapse of lumbar intervertebral disc is the reason that lumbago and skelalgia is possible.Thereafter, Barr and Mixter propose first relevant lumbar intervertebral disc dash forward Go out concept and the Therapeutic Method of disease.Hereafter, lumbar intervertebral disc prominent (taking off) is gone out the basic research of disease the most deeply, thus more Improve the clinical diagnosis of primary disease and the effect for the treatment of.
Prolapse of lumbar intervertebral disc, is primarily due to lumbar intervertebral disc each several part (vertebral pulp, fibrous ring and cartilaginous lamina), especially marrow Core, after having degenerative change in various degree, under the effect of external force factor, the Anular disruption of intervertebral disc, nucleus pulposus from Rupture part prominent (or abjection), in rear or intraspinal tube, to cause adjacent ridge nerve root stimulated or oppress, thus produce waist Portion's pain, a series of clinical symptoms such as side lower limb or double numbness of lower limbs, pain.According to prominent position can be divided into central type, The other type of central authorities, lateral and far lateral.Some types projecting degree is heavier, and chronic phase sharp ache.
The method of clinical treatment chronic lumbar vertebrae disc herniation is more, but curative effect is the most not ideal enough, and treatment cycle is long, and treats Imitate the most notable.
Summary of the invention
It is an object of the invention to provide a kind of good effect, low cost, have no side effect for treating prolapse of lumbar intervertebral disc Medicine.
The technical scheme realizing the object of the invention is:
A kind of medicine for treating prolapse of lumbar intervertebral disc, is made up of the raw material of following weight parts proportioning:
Eupolyphoge sinensis 5-15 part, Scorpio 5-15 part, Zaocys 5-15 part, Flos Carthami 12-24 part, Radix Angelicae Pubescentis 8-15 part, Radix Saposhnikoviae 5-15 part, Rhizoma Curculiginis 12-18 part, Cortex Eucommiae 8-15 part, Radix Morindae Officinalis 15-20 part, Squama Manis 5-15 part, Pheretima 18-25 part, Radix Aconiti Kusnezoffii 8-15 part, Semen Strychni Sub-8-18 part, Radix Notoginseng 15-25 part.
The above-mentioned medicine for treating prolapse of lumbar intervertebral disc, optimum weight part proportioning of each raw material is:
Eupolyphoge sinensis 10 parts, Scorpio 10 parts, Zaocys 10 parts, 18 parts of Flos Carthami, Radix Angelicae Pubescentis 12 parts, Radix Saposhnikoviae 10 parts, Rhizoma Curculiginis 15 parts, the Cortex Eucommiae 12 parts, Radix Morindae Officinalis 18 parts, Squama Manis 10 parts, Pheretima 22 parts, Radix Aconiti Kusnezoffii 12 parts, Semen Strychni 13 parts, Radix Notoginseng 20 parts.
Described raw medicinal material is in shop of Chinese medicines and commercially available.
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, after adding alcohol dipping 6-8 days that 5-7 times of concentration of material quantity is 40-60%, filter and remove residue, decompression filtrate recycling ethanol is extremely Taste without alcohol, obtains concentrated solution 80-100 part, standby;
(2) in the concentrated solution that step (1) prepares, add 800-1000 part water and 0.8-1 part potassium sorbate, stir evenly, stand 24-30h, filters, obtains filtrate, standby;
(3) separately with 60-100 part sucrose, add 120-140 part water boil 30-40min, filter, standby;
(4) the filtrate mixing of step (2) and (3) is placed in container, adds 800-1000 part water, bottle after cooling, seal After carry out sterilization treatment, make product.
In the present invention, the pharmacology of each crude drug, effect are as follows:
Eupolyphoge sinensis: removing blood stasis with potent drugs blood, reuniting the fractured tendons and bones.For injured bone, blood stasis amenorrhea, lump in the abdomen mass in the abdomen.
Scorpio: endogenous wind stopping spasmolytic, removing obstruction in the collateral to relieve pain, dispersing pathogen accumulation.For liver-wind stirring up internally, spasm is twitched, infantile convulsion, middle air portHemiplegia, tetanus, rheumatoid arthritis stubborn, migraine and general headache, skin infection, scrofula.
Zaocys: dispel the wind, dredging collateral, effect of relieving convulsion.For treating rheumatoid arthritis stubborn, numbness contracture, middle air port eye fish sticking its mouth out of the water tiltedly, Hemiplegia, tic spasm, tetanus, leprosy, scabies.
Flos Carthami: there is promoting blood circulation to restore menstrual flow, effect of eliminating stasis to stop pain.For amenorrhea, dysmenorrhea, lochia, lump in the abdomen mass in the abdomen, the thoracic obstruction Pained, the stagnant stomachache of the stasis of blood, breast side of body twinge, injury from falling down, skin infection swells and ache.
Radix Angelicae Pubescentis: expelling wind and dampness;Dispersing cold for relieving pain.For anemofrigid-damp arthralgia;Lumbocrural pain;Few the moon volt wind headache, toothache of having a headache.
Radix Saposhnikoviae: have expelling pathogenic wind from the body surface, removing dampness to relieve pain, effect of relieving convulsion.
Rhizoma Curculiginis: there is reinforcing the kidney and supporting YANG, benefiting essence-blood, bone and muscle strengthening and the effect of promoting the circulation of blood detumescence, be mainly used in insufficiency of kidney-YANG, sexual impotence The diseases such as seminal emission, chronic consumptive disease internal injury and bones and muscles pain.
The Cortex Eucommiae: be the dry bark of the Eucommiaceae plant Cortex Eucommiae, is Chinese famous and precious tonic herb.Its sweet in the mouth, warm in nature.There is benefit Liver and kidney tonifying, bone and muscle strengthening, Chong and Ren Meridians regulating, solid through antiabortive effect.The lumbago and skelalgia or aching and limp unable that insufficiency of kidney-YANG causes, liver can be treated The diseases such as born of the same parents' tire that the deficiency of vital energy causes is not solid, scrotum pruritus due to damp pathogen.
Squama Manis: can blood circulation promoting and dispersing pathogen accumulation, stimulating milk secretion of stimulating the menstrual flow, the routed heavily fortified point of eliminating carbuncle.Main blood stasis amenorrhea, lump in the abdomen, rheumatic arthralgia, agalactia, Carbuncle, scrofula etc..
Pheretima: have heat clearing away arresting convulsion, dredging collateral, relieving asthma, effect of diuresis.After parch for high heat, coma, infantile convulsion tic, The diseases such as arthralgia, dyspnea and cough due to lung-heat, oliguria edema, hypertension.
Radix Aconiti Kusnezoffii: expelling wind and removing dampness, antalgic.For anemofrigid-damp arthralgia, arthralgia, trusted subordinate's cold type of pain, colic of cold type is had a pain, and anaesthetizes Pain relieving.
Semen Strychni: 1. removing obstruction in the collateral to relieve pain: numb with dispelling the wind and dampness pathogens insensitive impediment or contracture.2, dispersing swelling and dissipating binds: with controlling wound pain caused by ecchymoma And ulcer sore pain.In recent years plant cancerous protuberance with Zhiduo County, have certain curative effect.3. treatment poliomyelitis sequela, prolapse of lumbar intervertebral disc, three Fork neuralgia, rheumatoid arthritis, traumatic injury, pain due to blood stasis, anemofrigid-damp arthralgia, general joint contracture, numbness, cancerous protuberance etc.. Cure mainly throat arthralgia pain, swollen ulcer drug, migratory arthralgia pain, fracture, facial paralysis, myasthenia gravis.
Radix Notoginseng: dissipating blood stasis stops blooding, subduing swelling and relieving pain.For spitting blood, spit blood, epistaxis, to have blood in stool, metrorrhagia, traumatic hemorrhage, chest and abdomen sting Bitterly, tumbling and swelling.
The present invention, for treating the medicine of prolapse of lumbar intervertebral disc, chooses 14 kinds of natural Chinese medicine scientific compatibility, and formula is simple, respectively Crude drug synergism plays blood circulation promoting and blood stasis dispelling, the effect of reducing swelling and alleviating pain, instant effect, and treating both the principal and secondary aspects of a disease has no side effect, and its system Preparation Method is simple, taking convenience, low cost.
Detailed description of the invention
Below in conjunction with embodiment, present invention is further described, but is not limitation of the invention.
Embodiment 1
A kind of medicine for treating prolapse of lumbar intervertebral disc, is made up of the raw material of following weight parts proportioning:
Eupolyphoge sinensis 5kg, Scorpio 5kg, Zaocys 5kg, Flos Carthami 12kg, Radix Angelicae Pubescentis 8kg, Radix Saposhnikoviae 5kg, Rhizoma Curculiginis 12kg, Cortex Eucommiae 8kg, Radix Morindae Officinalis 15kg, Squama Manis 5kg, Pheretima 18kg, Radix Aconiti Kusnezoffii 8kg, Semen Strychni 8kg, Radix Notoginseng 15kg.
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, adding 5 times of concentration of material quantity is the alcohol dipping of 40% after 6 days, filter and remove residue, decompression filtrate recycling ethanol to without alcohol taste, Obtain concentrated solution 80kg, standby;
(2) in the concentrated solution that step (1) prepares, add 800kg water and 0.8kg potassium sorbate, stir evenly, stand 24h, mistake Filter, obtains filtrate, standby;
(3) separately use 60kg sucrose, add 120kg water boil 30min, filter, standby;
(4) filtrate of step (2) and (3) mixed be placed in container, add 800kg water, bottle after cooling, seal after carry out Sterilization treatment, makes product.
Embodiment 2
A kind of medicine for treating prolapse of lumbar intervertebral disc, is made up of the raw material of following weight parts proportioning:
Eupolyphoge sinensis 10kg, Scorpio 10kg, Zaocys 10kg, Flos Carthami 18kg, Radix Angelicae Pubescentis 12kg, Radix Saposhnikoviae 10kg, Rhizoma Curculiginis 15kg, the Cortex Eucommiae 12kg, Radix Morindae Officinalis 18kg, Squama Manis 10kg, Pheretima 22kg, Radix Aconiti Kusnezoffii 12kg, Semen Strychni 13kg, Radix Notoginseng 20kg.
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, adding 6 times of concentration of material quantity is the alcohol dipping of 50% after 7 days, filter and remove residue, decompression filtrate recycling ethanol to without alcohol taste, Obtain concentrated solution 90kg, standby;
(2) in the concentrated solution that step (1) prepares, add 900kg water and 0.9kg potassium sorbate, stir evenly, stand 27h, mistake Filter, obtains filtrate, standby;
(3) separately use 80kg sucrose, add 130kg water boil 35min, filter, standby;
(4) filtrate of step (2) and (3) mixed be placed in container, add 900kg water, bottle after cooling, seal after carry out Sterilization treatment, makes product.
Embodiment 3
A kind of medicine for treating prolapse of lumbar intervertebral disc, is made up of the raw material of following weight parts proportioning:
Eupolyphoge sinensis 15kg, Scorpio 15kg, Zaocys 15kg, Flos Carthami 24kg, Radix Angelicae Pubescentis 15kg, Radix Saposhnikoviae 15kg, Rhizoma Curculiginis 18kg, the Cortex Eucommiae 15kg, Radix Morindae Officinalis 20kg, Squama Manis 15kg, Pheretima 25kg, Radix Aconiti Kusnezoffii 15kg, Semen Strychni 18kg, Radix Notoginseng 25kg.
The preparation method of medicine of the present invention is as follows:
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, are mixed together and are placed in container In, adding 7 times of concentration of material quantity is the alcohol dipping of 60% after 8 days, filter and remove residue, decompression filtrate recycling ethanol to without alcohol taste, Obtain concentrated solution 100kg, standby;
(2) in the concentrated solution that step (1) prepares, add 1000kg water and 1kg potassium sorbate, stir evenly, stand 30h, mistake Filter, obtains filtrate, standby;
(3) separately use 100kg sucrose, add 140kg water boil 40min, filter, standby;
(4) filtrate of step (2) and (3) mixed be placed in container, add 1000kg water, bottle after cooling, seal laggard Row sterilization treatment, makes product.
In order to prove the clinical efficacy of Chinese medicine of the present invention further, select to accept 90 examples in patient for medical treatment, to medicine of the present invention Curative effect carry out clinical observation.In age 30-50 year, being randomly divided into 3 groups, often group is 30 examples, respectively experimental group 1-3 group.
Experimental group 1-3 group takes the medicine of embodiment 1-3 respectively, three times a day, takes 3g with yellow wine every time, within 20 days, is one The individual course for the treatment of, take 1-2 the course for the treatment of continuously.The most effective 84 examples, effective 86 examples, cure 83 examples, invalid 4 examples, cure rate 92%, have Efficiency 96%.

Claims (7)

1., for treating a medicine for prolapse of lumbar intervertebral disc, it is characterized in that: be made up of the raw material of following weight parts proportioning:
Eupolyphoge sinensis 5-15 part, Scorpio 5-15 part, Zaocys 5-15 part, Flos Carthami 12-24 part, Radix Angelicae Pubescentis 8-15 part, Radix Saposhnikoviae 5-15 part, Rhizoma Curculiginis 12-18 part, Cortex Eucommiae 8-15 part, Radix Morindae Officinalis 15-20 part, Squama Manis 5-15 part, Pheretima 18-25 part, Radix Aconiti Kusnezoffii 8-15 part, Semen Strychni 8- 18 parts, Radix Notoginseng 15-25 part.
Medicine for treating prolapse of lumbar intervertebral disc the most according to claim 1, is characterized in that: the weight portion of each raw material is joined Than being:
Eupolyphoge sinensis 10 parts, Scorpio 10 parts, Zaocys 10 parts, 18 parts of Flos Carthami, Radix Angelicae Pubescentis 12 parts, Radix Saposhnikoviae 10 parts, Rhizoma Curculiginis 15 parts, the Cortex Eucommiae 12 Part, Radix Morindae Officinalis 18 parts, Squama Manis 10 parts, Pheretima 22 parts, Radix Aconiti Kusnezoffii 12 parts, Semen Strychni 13 parts, Radix Notoginseng 20 parts.
3., for treating a preparation method for the medicine of prolapse of lumbar intervertebral disc, it is characterized in that: specifically comprise the following steps that
(1) weigh each crude drug by weight ratio, whole crude drug are ground into coarse powder, be mixed together and be placed in container, add After entering alcohol dipping 6-8 days of 5-7 times of concentration of material quantity, filter and remove residue, decompression filtrate recycling ethanol, to without alcohol taste, obtains concentrated solution 80-100 part is standby;
(2) in the concentrated solution that step (1) prepares, add water and potassium sorbate, stir evenly, stand 24-30h, filter, obtain filtrate, standby With;
(3) separately with sucrose, add water boil 30-40min, filter, standby;
(4) filtrate of step (2) and (3) mixed be placed in container, add water, bottle after cooling, seal after carry out sterilization treatment, Make product.
The preparation method of the medicine for treating prolapse of lumbar intervertebral disc the most according to claim 3, is characterized in that: described step The concentration of the ethanol suddenly added in (1) is 40-60%.
The preparation method of the medicine for treating prolapse of lumbar intervertebral disc the most according to claim 3, is characterized in that: described step Suddenly in (2), the addition of water is 800-1000 part, and the addition of potassium sorbate is 0.8-1 part.
The preparation method of the medicine for treating prolapse of lumbar intervertebral disc the most according to claim 3, is characterized in that: described step Suddenly the amount of the sucrose in (3) is 60-100 part, and the amount of water is 120-140 part.
The preparation method of the medicine for treating prolapse of lumbar intervertebral disc the most according to claim 3, is characterized in that: described step Suddenly in (4), the addition of water is 800-1000 part.
CN201610673578.2A 2016-08-16 2016-08-16 For treating the medicine of prolapse of lumbar intervertebral disc Pending CN106109760A (en)

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Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105012592A (en) * 2015-07-27 2015-11-04 刘杰 Drug for treatment of chronic lumbar disc herniation

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN105012592A (en) * 2015-07-27 2015-11-04 刘杰 Drug for treatment of chronic lumbar disc herniation

Non-Patent Citations (1)

* Cited by examiner, † Cited by third party
Title
余宜春: "综合保守治疗腰椎间盘突出症250例", 《中医药临床杂志》 *

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