CN106109319A - A kind of oral nursing liquid and preparation method thereof - Google Patents
A kind of oral nursing liquid and preparation method thereof Download PDFInfo
- Publication number
- CN106109319A CN106109319A CN201610601096.6A CN201610601096A CN106109319A CN 106109319 A CN106109319 A CN 106109319A CN 201610601096 A CN201610601096 A CN 201610601096A CN 106109319 A CN106109319 A CN 106109319A
- Authority
- CN
- China
- Prior art keywords
- parts
- oral
- nursing liquid
- borneolum syntheticum
- magnesium silicate
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Pending
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/23—Sulfur; Selenium; Tellurium; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/19—Cosmetics or similar toiletry preparations characterised by the composition containing inorganic ingredients
- A61K8/25—Silicon; Compounds thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/34—Alcohols
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/33—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing oxygen
- A61K8/36—Carboxylic acids; Salts or anhydrides thereof
- A61K8/365—Hydroxycarboxylic acids; Ketocarboxylic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/30—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
- A61K8/49—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds
- A61K8/494—Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing heterocyclic compounds with more than one nitrogen as the only hetero atom
- A61K8/4946—Imidazoles or their condensed derivatives, e.g. benzimidazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/72—Cosmetics or similar toiletry preparations characterised by the composition containing organic macromolecular compounds
- A61K8/73—Polysaccharides
- A61K8/733—Alginic acid; Salts thereof
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/92—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof
- A61K8/922—Oils, fats or waxes; Derivatives thereof, e.g. hydrogenation products thereof of vegetable origin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q11/00—Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61Q—SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
- A61Q17/00—Barrier preparations; Preparations brought into direct contact with the skin for affording protection against external influences, e.g. sunlight, X-rays or other harmful rays, corrosive materials, bacteria or insect stings
- A61Q17/005—Antimicrobial preparations
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Birds (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Emergency Medicine (AREA)
- Biotechnology (AREA)
- Botany (AREA)
- Microbiology (AREA)
- Mycology (AREA)
- Engineering & Computer Science (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Oral & Maxillofacial Surgery (AREA)
- Dermatology (AREA)
- Cosmetics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Medicinal Preparation (AREA)
Abstract
The present invention relates to a kind of oral nursing liquid, it is made up of according to weight fraction following components: active ionized calcium 10 35 parts, Matrii Sulfas Exsiccatus 39 parts, Borneolum Syntheticum 13 parts, Flos Caryophylli bud quintessence oil 5 15 parts, lithium magnesium silicate 0.5 3 parts, Aloe extract 3.5 11 parts, sodium alginate 15 parts, allantoin 15 parts, citric acid 13 parts.The oral nursing liquid of the present invention for reducing because of Abwehrkraft des Koepers, oral cavity self-cleaning action weakens, in oral cavity dysbacteriosis and cause oral inflammation, ulcer, sinusitis, the illness such as otitis media.Also it is applicable in oral cavity implement sterilization and the sterilization in oral cavity before and after operation (exodontia, Dental Implant etc.) is treated, collection cleaning, degerming, the oral nursing liquid of nursing effect.
Description
Technical field
The present invention relates to sterilizing cleaning articles for use, particularly to a kind of oral nursing liquid and preparation method thereof.
Background technology
Oral cavity is one of main path of pathogenic microorganism intrusion human body.With the presence of substantial amounts of antibacterial in normal person oral cavity,
Wherein having plenty of pathogenic bacterium, when resistance of human body reduces, and drinking-water, food-intake are few, chew and the action of tongue reduces, salivation is not
Foot, when self-cleaning action is impacted, antibacterial can seize the opportunity and breed rapidly in moistening, warm oral cavity, cause oral inflammation, ulcer,
The illness such as parotitis, otitis media；Even with blood, lymph, cause other organs infection, bring harm to whole body；Make for a long time
With the patient of antibiotics, fungal infection can be induced again due to dysbacteriosis.So, carry out mouth care particularly significant to patient,
Sooner or later brushing teeth and have become as the common oral care custom of modern, but research shows, the long-pending oral surfaces that only accounts for of dental surface amasss
25%, only by the cleaning that can not complete full oral cavity of brushing teeth, the antibacterial that oral cavity Midst density is higher can cause the acceleration of dental plaque
Accumulation.According to the suggestion of American Dental Association (ADA), proper use of collutory not only can be with fresh breath, moreover it is possible to decompose tooth bacterium
Speckle, prevention decayed tooth, gingivitis and the formation of dental calculus.Although collutory can not replace brushing teeth, but it from we life also
Do not become estranged, and use collutory can realize overall sterilizing oral afterwards brushing teeth.It addition, in order to the implication moment is pure and fresh, city
On face, collutory can be divided into prescription and the big class of OTC (over-the-counter) two, and the effective ingredient (such as hibitane) of prescription class collutory, if making for a long time
With dental stain can be caused, even there are certain side effect, 1%～3% hydrogenperoxide steam generator: anticorrosion, deodorant, it is adaptable to oral cavity
Infection have fester, slough person, 1%～4% sodium bicarbonate solution: belong to alkaline solution, it is adaptable to fungal infection, as mouth
Sense, the spirit solvent too aggressive in this type of collutory, but it has to be noticed that " ethanol in collutory is carcinogenic ", some collutory
In containing ethanol or class antibiotic.Normal oral bacteria ecology may be destroyed, kill profitable strain, cause flora disorderly
Disorderly；If the collutory of class antibiotic is also possible to make antibacterial produce drug resistance.
Summary of the invention
For problems of the prior art, the present invention provides a kind of oral nursing liquid and preparation method thereof.
Technical scheme is as follows:
A kind of oral nursing liquid, is made up of according to weight fraction following components:
Active ionized calcium 10-35 part, Matrii Sulfas Exsiccatus 3-9 part, Borneolum Syntheticum 1-3 part, Flos Caryophylli bud quintessence oil 5-15 part, lithium magnesium silicate 0.5-
3 parts, Aloe extract 3.5-11 part, sodium alginate 1-5 part, allantoin 1-5 part, citric acid 1-3 part.
Preparation method specifically comprises the following steps that
(1) Borneolum Syntheticum is added in the medical alcohol of 10ml and dissolve, standby；Lithium magnesium silicate is added the deionized water of 300ml
In, stir evenly, standby；
(2) being dissolved in the deionized water of 200ml by active ionized calcium, uniform stirring, to all dissolving, sequentially adds profound
Bright powder, Borneolum Syntheticum solution, sodium alginate, uniform stirring, add allantoin and lithium magnesium silicate solution, mix homogeneously；
(3) 25 minutes are stood, after removing bubble, evacuation 0.1mmHg deaeration；Then add Aloe extract, stir 15
Minute, static in a moment, add Flos Caryophylli bud quintessence oil；
(4) citric acid, static 24h are added.
1, active ionized calcium is water-soluble active powder, meets water and i.e. dissolves, and it mainly comprises five kinds of main hot spring level alkalescence
Mineral, exists with ionic forms: calcium ion (Ca2+), magnesium ion (Mg2+), potassium ion (K+), sodium ion (Na+), germanium ion
(Ge2+), easily it is absorbed by the body.Calcium ion powder: use the raw materials such as natural Margarita, Corallium Japonicum Kishinouye, Achates, Concha Ostreae, application height
Science and technology ion exchange and calcining rich in calcium, magnesium, potassium, sodium, manganese, the preparation of germanium ion, based on calcium ion.Calcium ion
Calcining heat typically all at 1,400 1800 degree, there is toxin expelling, hyperoxia, alkalescence, activity. alkalescence can bacteria growing inhibiting, especially
At antioxidation, anti-inflammatory, sterilize, sterilize, promote epidermis blood circulation, get rid of toxin, and then improve human body from outside to inside new
When old metabolism human body acid poison is higher, cell will face death and cause inflammation phenomenon, or injured cell faces death, with
And wound infection antibacterial etc., all will cause inflammation phenomenon, owing to calcium ion can neutralize acid poison, active cell, and make antibacterial without
Method is survived, and inflammation phenomenon therefore can be made to rapidly disappear, and China marine site is vast, has abundant living marine resources, its production technology
Simply, raw material sources are extensive, thus popularizing application prospect is wide.
2, lithium magnesium silicate: this product is silicate mineral material, has nano microcrystalline structure.In water, dispersion forms transparence
Thixotropy colloid, dispersed particle size size about 20-50 nanometer.Inorganic substances, not by antibacterial and heated mechanical failure by shear
Decomposing, will not will not be gone mouldy by microbial attack, viscosity does not varies with temperature, and can be hydrated with ionized water at normal temperatures, expand
For suspension colloid, good weatherability.When concentration is 1.5 one 2.5%, forms transparent or semitransparent thixotropic solution, eliminate and add
Thermal technology's sequence, the calcium in energy-saving convenient lithium magnesium silicate, magnesium ion are all the important component parts of skeleton and tooth；Magnesium share with calcium,
Absorbing of calcium can be helped, reduce calcareous loss, consolidate skeleton and tooth；Magnesium share with calcium, can prevent osteoporosis.
Gum can be good for for toothpaste to clean the teeth
3, citric acid:
Chemical composition: citric acid is a kind of tricarboxylic acids compounds, and therefore and to other carboxylic acids have similar physics and
Chemical property.When being heated to 175 DEG C, it can decompose generation carbon dioxide and water, remains some white crystals.Citric acid is a kind of
Stronger organic acid, has 3 H+ to ionize；Heating can resolve into multi-products, reacts with acid, alkali, glycerol etc..
Effect and pharmacology: sterilize, promote infiltration, adjustment vascular permeability
4, sodium alginate has another name called sodium alginate, seaweed gel, Algin, alginate, is by the natural polysaccharide extracted in Thallus Laminariae (Thallus Eckloniae)
Carbohydrate.Be widely used in food, weave, print and dye, papermaking, the product such as daily-use chemical industry, gingiva pharmaceutically can be suppressed to go out
Blood.
5, allantoin effectively suppresses dental plaque, protection mucosal tissue, promotes hyperplasia；
6, to be that Natrii Sulfas is dried through air slaking prepared for Matrii Sulfas Exsiccatus.Main sulfur acid sodium (Na2SO4).
[character] this product is white powder.Odorless, salty in the mouth.Have draw moist.
[nature and flavor with return through] are salty, bitter, cold.Return stomach, large intestine channel.
[function with cure mainly] purging heat to relax the bowels, moistening for dryness and softening hard mass, detumescence of relieving inflammation or internal heat.For excess-heat constipation, constipation due to dry stool, stagnant abdomen
Bitterly；External treatment laryngopharynx swelling and pain, aphtha of the mouth and tongue, gingival swelling and pain, conjunctival congestion, carbuncle, erysipelas.
7, Borneolum Syntheticum has an antiphlogistic and bactericidal function, therefore often and Oleum menthae is with for dentifrice, prickly-heat powder, Oleum concha Mactrae and Folium Pini abnormal smells from the patient
Spray etc..
8, Flos Caryophylli bud quintessence oil has the function of anti-inflammatory analgetic, to toothache, headache, dysmenorrhea, stomachache, rheumatalgia and arthritis
Deng there being good curative effect.
9, containing abundant glue liquid in the blade that Aloe is plump, this glue liquid has prevents and treats ulcer, promotes wound
Mouth healing, stimulating cellular growth and the effect of hemostasis, be also a kind of natural preservative and wetting agent.
Flos Caryophylli bud quintessence oil goods number of the present invention: ECO_CL, Aloe extraction elite goods number: RMNAB purchase in Xiang source
Asia company limited
The oral nursing liquid of the present invention has good cleaning, degerming, nursing effect, and in raw material, each component cooperates,
Reach cleaning, the effect of degerming nursing；Oral nursing liquid of the present invention is for subtracting because of Abwehrkraft des Koepers reduction, oral cavity self-cleaning action
Dysbacteriosis in weak, oral cavity and cause oral inflammation, ulcer, sinusitis, the illness such as otitis media.Also it is applicable in oral cavity real
Operate on the sterilization in oral cavity and sterilization before and after (exodontia, Dental Implant etc.) treatment, collection cleaning, degerming, the mouth care of nursing effect
Liquid.Without any zest, without chemical sterilization composition, not spirituosity.Colourless transparent liquid.Meanwhile, preparation method of the present invention letter
Single, but the order of addition of considered critical raw material, make conditioning liquid reach optimal effect.
Detailed description of the invention
Following example are used for illustrating the present invention, but are not limited to the scope of the present invention.Without departing substantially from present invention spirit
In the case of essence, the amendment that the inventive method, step or condition are made or replacement, belong to the protection model of the present invention
Enclose.
If not specializing, the conventional means that technological means used in embodiment is well known to those skilled in the art.
A kind of oral nursing liquid, is made up of according to weight following components:
Active ionized calcium 10g, Matrii Sulfas Exsiccatus 3g, Borneolum Syntheticum 1g, Flos Caryophylli bud quintessence oil 5g, lithium magnesium silicate 0.5g, Aloe extract
3.5g, sodium alginate 1g, allantoin 1g, citric acid 1g.
Preparation method specifically comprises the following steps that
(1) Borneolum Syntheticum is added in the medical alcohol of 10ml and dissolve, standby；Lithium magnesium silicate is added the deionized water of 300ml
In, stir evenly, standby；
(2) being dissolved in the deionized water of 200ml by active ionized calcium, uniform stirring, to all dissolving, sequentially adds profound
Bright powder, Borneolum Syntheticum solution, sodium alginate, uniform stirring, add allantoin and lithium magnesium silicate solution, mix homogeneously；
(3) 25 minutes are stood, after removing bubble, evacuation 0.1mmHg deaeration；Then add Aloe extract, stir 15
Minute, static in a moment, add Flos Caryophylli bud quintessence oil；
(4) citric acid, static 24h are added.
Embodiment 2
A kind of oral nursing liquid, is made up of according to weight following components:
Active ionized calcium 20g, Matrii Sulfas Exsiccatus 6g, Borneolum Syntheticum 2g, Flos Caryophylli bud quintessence oil 10g, lithium magnesium silicate 1.5g, Aloe extract
8g, sodium alginate 3g, allantoin 3g, citric acid 2g.
Embodiment 3
A kind of oral nursing liquid, is made up of according to weight following components:
Active ionized calcium 35g, Matrii Sulfas Exsiccatus 9g, Borneolum Syntheticum 3g, Flos Caryophylli bud quintessence oil 15g, lithium magnesium silicate 3g, Aloe extract 11g,
Sodium alginate 5g, allantoin 5g, citric acid 3g.
Preparation method is same as in Example 1.
Embodiment 1
The present invention chooses Dental implantion patient 6 people, male 4 people, women 2 people, and the age, between 35-55 year, is randomly divided into two
Group, one group of patient gargles with compound recipe hibitane the most afterwards, and one group of patient gargles with oral nursing liquid of the present invention the most afterwards
Mouthful, both of which uses preoperative rinsing the mouth twice, each 3 minutes, and each 5ml gargles 3-4 time postoperative every day, and each rinsing the mouth 3-5 divides
Clock.Patient takes out stitches and observes situation in patient's mouth for 7 days.
Result
The most there is not the phenomenon infected in the patient using compound recipe hibitane oral nursing liquid of the present invention, takes out stitches smoothly, effect
Fruit is satisfied.But using in the patient of compound recipe hibitane, there is coloring in various degree on tongue body surface, inquires patient, and coloring degree is relatively
Deep patient compliance is preferable, and every day uses compound recipe record the most surely to gargle in strict accordance with doctor's advice.And use benefit and Li Yuan oral cavity clear
One group of patient of cleaning and nursing liquid none be found to have tongue body coloring appearance.
Test example two
The present invention chooses health adult 20 people, is randomly divided into two groups, and two groups of people the most first gargle with normal saline, for avoiding taking
Sample difference has same people, samples in 20 human mouth, carries out labelling and send antibacterial culturing.Following 10 people one group, uses compound recipe for one group
Hibitane rinsing the mouth spues after 5 minutes sampling, another group beneficial and vertical source oral cavity cleaning and nursing liquid rinsing the mouth five minutes, carries out labelling,
Send antibacterial culturing, observe the change of bacterium colony before and after 20 people's samplings, and the contrast of two bacterium colony situations after gargling.
After cultivating due to oral cavity sampling, colony count is more, and normal saline samples total plate count location 1 after gargling, observe two
After group is gargled, clump count changes, and one group of normal saline by major part killing bacteria in oral cavity about more than 70%, but can examine not
Difficult discovery, and the sterilization effect of oral nursing liquid of the present invention a group is more than 90%.
Interpretation of result
Oral cavity cleaning and nursing liquid of the present invention is the same with compound recipe hibitane effect a strongest sterilization effect, but mouth of the present invention
Chamber cleaning-nursing liquid has its irreplaceable colourless, nontoxic, non-stimulated, preservative free, and can sterilize rapidly, and life-time service is without pair
Effect.
The advantage of effect.Its main component active ionized calcium and Borneolum Syntheticum, colourless, nontoxic, non-stimulated, preservative free, can be fast
Speed sterilization also forms protecting film, and test proves that long-time use has no side effect, and has no drug resistance, and using method is the most square
Just, greatly simplify clinical manipulation step relative to povidone iodine, compound recipe hibitane, save the time, be more convenient for clinical practice
Sterilizing: oral nursing liquid composition of the present invention is mainly the solution group that main component is made by active ionized calcium and Borneolum Syntheticum
Becoming, active ionized calcium is directly entered thalline, makes the unique mechanism of action that thalline is choked to death, and can kill the mankind being in contact with it
The microorganisms such as the various bacteria known, fungus, mycete, spore.It is to pathogenic bacteria of drug-resistant such as antibiotic-resistance E. coli, drug resistance gold Fructus Vitis viniferae ball
Bacterium, drug-resistant pseudomonas aeruginosa, streptococcus pyogenes, drug resistance enterococcus, anaerobe etc. has comprehensive antibacterial activity；Burn and scald is injured wound
Common antibacterial such as staphylococcus aureus, escherichia coli, bacillus pyocyaneus, Candida albicans and other G+, the G-in surface causes a disease
Bacterium has bactericidal action；To rhinitis, draw otitis media and also have powerful anti-inflammation and sterilization effect.
The embodiment above is the embodiment that the present invention is optimal, but embodiment of the present invention are not by above-mentioned embodiment party
The restriction of case, other any under conditions of the principle of the invention, can be real by changing produced by the form of parameter
Execute example, within being all contained in protection scope of the present invention.
Claims (4)
1. an oral nursing liquid, it is characterised in that composed of the following components:
Active ionized calcium, Matrii Sulfas Exsiccatus, Borneolum Syntheticum, Flos Caryophylli bud quintessence oil, lithium magnesium silicate, Aloe extract, sodium alginate, allantoin, Chinese holly
Rafter acid.
Oral nursing liquid the most according to claim 1, it is characterised in that be made up of according to weight fraction following components:
Active ionized calcium 10-35 part, Matrii Sulfas Exsiccatus 3-9 part, Borneolum Syntheticum 1-3 part, Flos Caryophylli bud quintessence oil 5-15 part, lithium magnesium silicate 0.5-3 part,
Aloe extract 3.5-11 part, sodium alginate 1-5 part, allantoin 1-5 part, citric acid 1-3 part.
Oral nursing liquid the most according to claim 2, it is characterised in that be made up of according to weight fraction following components:
Active ionized calcium 20 parts, Matrii Sulfas Exsiccatus 6 parts, Borneolum Syntheticum 2 parts, Flos Caryophylli bud quintessence oil 10 parts, lithium magnesium silicate 1.5 parts, Aloe extract 8
Part, sodium alginate 3 parts, allantoin 3 parts, citric acid 2 parts.
4. the preparation method according to the oral nursing liquid described in any one of claim 1-3, it is characterised in that concrete steps
As follows:
(1) Borneolum Syntheticum is added in 20ml medical alcohol dissolve, standby；Lithium magnesium silicate is added in the deionized water of 300ml, stir
Even, standby；
(2) active ionized calcium is dissolved in the deionized water of 200ml, uniform stirring to all dissolving, sequentially add Matrii Sulfas Exsiccatus,
Borneolum Syntheticum solution, sodium alginate, uniform stirring, add allantoin and lithium magnesium silicate solution, mix homogeneously；
(3) 25 minutes are stood, after removing bubble, evacuation 0.1mmHg deaeration；Then add Aloe extract, stir 15 minutes,
Static in a moment, add Flos Caryophylli bud quintessence oil；
(4) citric acid, static 24h are added.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610601096.6A CN106109319A (en) | 2016-07-28 | 2016-07-28 | A kind of oral nursing liquid and preparation method thereof |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610601096.6A CN106109319A (en) | 2016-07-28 | 2016-07-28 | A kind of oral nursing liquid and preparation method thereof |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| CN106109319A true CN106109319A (en) | 2016-11-16 |
Family
ID=57290047
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610601096.6A Pending CN106109319A (en) | 2016-07-28 | 2016-07-28 | A kind of oral nursing liquid and preparation method thereof |
Country Status (1)
| Country | Link |
|---|---|
| CN (1) | CN106109319A (en) |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| RU2712121C1 (en) * | 2018-11-29 | 2020-01-24 | Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "Институт биологии южных морей имени А.О. Ковалевского РАН" (ФИЦ ИнБЮМ) | Oral and throat care means |
| CN110856702A (en) * | 2018-08-23 | 2020-03-03 | 上海利康消毒高科技有限公司 | Dental implant oral care gel and preparation method thereof |
Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1080531A (en) * | 1993-06-08 | 1994-01-12 | 夏学东 | Quick effect active ion calcium |
| CN101416925A (en) * | 2008-10-27 | 2009-04-29 | 郭进军 | Child edible mouth cleaning solution formulation, production technique and tooth-protection infection prevention effect |
| CN103120703A (en) * | 2013-01-06 | 2013-05-29 | 王峥 | Care solution for cleaning nasal cavity and related composition |
| CN104721117A (en) * | 2015-02-12 | 2015-06-24 | 青岛食安生物工程有限公司 | Active calcium bacteriostatic mouth wash |
-
2016
- 2016-07-28 CN CN201610601096.6A patent/CN106109319A/en active Pending
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN1080531A (en) * | 1993-06-08 | 1994-01-12 | 夏学东 | Quick effect active ion calcium |
| CN101416925A (en) * | 2008-10-27 | 2009-04-29 | 郭进军 | Child edible mouth cleaning solution formulation, production technique and tooth-protection infection prevention effect |
| CN103120703A (en) * | 2013-01-06 | 2013-05-29 | 王峥 | Care solution for cleaning nasal cavity and related composition |
| CN104721117A (en) * | 2015-02-12 | 2015-06-24 | 青岛食安生物工程有限公司 | Active calcium bacteriostatic mouth wash |
Non-Patent Citations (2)
| Title |
|---|
| 杨进 等: "《一百天学中药》", 31 October 2015, 上海科学技术出版社 * |
| 耿春芳 等: ""益和立源口腔清洁护理液在消毒***中的应用"", 《中外健康文摘》 * |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN110856702A (en) * | 2018-08-23 | 2020-03-03 | 上海利康消毒高科技有限公司 | Dental implant oral care gel and preparation method thereof |
| RU2712121C1 (en) * | 2018-11-29 | 2020-01-24 | Федеральное государственное бюджетное учреждение науки Федеральный исследовательский центр "Институт биологии южных морей имени А.О. Ковалевского РАН" (ФИЦ ИнБЮМ) | Oral and throat care means |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| Haapasalo et al. | Eradication of endodontic infection by instrumentation and irrigation solutions | |
| KR101481371B1 (en) | Toothpaste composition containing Curcuma longa L and production method thereof | |
| CN107811890A (en) | A kind of oral cavity caring toothpaste composition | |
| Agarwal et al. | Comparison of antimicrobial efficacy of aqueous ozone, green tea, and normal saline as irrigants in pulpectomy procedures of primary teeth | |
| CN104207957B (en) | A kind of fibroin conditioning liquid with koro whitening function and preparation method thereof | |
| CN106538629A (en) | A kind of livestock-raising disinfectant and preparation method thereof | |
| CN102251438B (en) | Antiseptic fragrant paper towel and manufacturing method thereof | |
| CN102861206A (en) | Sterilizing and disinfecting aerosol for skin mucous membrane and preparation method thereof | |
| CN106109319A (en) | A kind of oral nursing liquid and preparation method thereof | |
| US4978535A (en) | Method for cleaning contact lenses | |
| CN106473961A (en) | A kind of gargarism and preparation method | |
| CN106265452A (en) | A kind of green lemon toothpaste and preparation method thereof | |
| CN104524559A (en) | Lysostaphic complex enzyme oral cavity disinfectant and preparation method thereof | |
| Teke et al. | In vitro antimicrobial activity of some commercial toothpastes | |
| CN104606085B (en) | A kind of chlorhexidine acetate nano-emulsion gargle of antibacterial and preparation method thereof | |
| WO2020087766A1 (en) | Use of benzofuran derivative | |
| CN110151574A (en) | A kind of stability chlorine dioxide gargle and preparation method thereof | |
| CN106420938B (en) | A kind of Chinese medicine composition and preparation method thereof for treating oral inflammation and pharyngitis | |
| CN1229104C (en) | Composition for preventing and curing gingivitis | |
| CN104324062A (en) | American ginseng conversion saponin, traditional Chinese medicine mouth care composition thereof and preparation method and application | |
| CN107485584A (en) | A kind of oral care composition | |
| CN109512683B (en) | Povidone-iodine composition and preparation method and application thereof | |
| CN1943625B (en) | Oral sterilizing liquid | |
| US20220313570A1 (en) | Use of magnesium hydride in preparation of composition for preventing and treating chronic periodontitis, and magnesium hydride toothpaste | |
| BR112021007388A2 (en) | BIOFLAVONOID COMPOSITIONS AND THEIR USE |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| C06 | Publication | ||
| PB01 | Publication | ||
| C10 | Entry into substantive examination | ||
| SE01 | Entry into force of request for substantive examination | ||
| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20161116 |