CN106086078B - 一种car‑t细胞毒性指示载体 - Google Patents
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Abstract
Description
指示细胞数目D | D10 | D100 | D1000 | D10000 | D100000 |
荧光素酶活力值 | 681 | 8554 | 85870 | 975411 | 31931660 |
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CN201610537806.3A CN106086078B (zh) | 2016-07-08 | 2016-07-08 | 一种car‑t细胞毒性指示载体 |
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Families Citing this family (5)
Publication number | Priority date | Publication date | Assignee | Title |
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CN106822184A (zh) * | 2016-12-15 | 2017-06-13 | 梁爱斌 | 多靶点联合的car‑t细胞制剂与制备方法 |
WO2019157691A1 (zh) | 2018-02-14 | 2019-08-22 | 宜明细胞生物科技有限公司 | 一种重组嵌合抗原受体基因及其应用 |
CN108753916A (zh) * | 2018-06-04 | 2018-11-06 | 杭州启澜生物医学技术有限公司 | 一种快速评估car-t细胞体外杀伤效率的方法 |
CN110129370B (zh) * | 2019-05-06 | 2021-07-20 | 山东昂科诺生物科技有限公司 | 一种car-t毒性指示细胞的快速构建方法 |
CN111358956B (zh) * | 2020-03-25 | 2021-07-09 | 南京鼓楼医院 | 一种纳米开关分子及其控制激活的实体瘤靶向性car-t细胞 |
Citations (3)
Publication number | Priority date | Publication date | Assignee | Title |
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CN104910279A (zh) * | 2015-06-05 | 2015-09-16 | 重庆倍思益生物科技有限公司 | 靶向癌胚抗原的嵌合抗原受体、慢病毒表达载体及其制备方法和应用 |
CN105418765A (zh) * | 2014-08-26 | 2016-03-23 | 西比曼生物科技(上海)有限公司 | Cd19靶向性的嵌合抗原受体和nkt细胞及其制法和应用 |
CN105602992A (zh) * | 2016-03-17 | 2016-05-25 | 上海优卡迪生物医药科技有限公司 | 一种基于复制缺陷性重组慢病毒的car-t转基因载体及其构建方法和应用 |
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Publication number | Priority date | Publication date | Assignee | Title |
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CN105418765A (zh) * | 2014-08-26 | 2016-03-23 | 西比曼生物科技(上海)有限公司 | Cd19靶向性的嵌合抗原受体和nkt细胞及其制法和应用 |
CN104910279A (zh) * | 2015-06-05 | 2015-09-16 | 重庆倍思益生物科技有限公司 | 靶向癌胚抗原的嵌合抗原受体、慢病毒表达载体及其制备方法和应用 |
CN105602992A (zh) * | 2016-03-17 | 2016-05-25 | 上海优卡迪生物医药科技有限公司 | 一种基于复制缺陷性重组慢病毒的car-t转基因载体及其构建方法和应用 |
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Effective date of registration: 20191115 Address after: Room 206, building 17, Life Science City, pharmaceutical Valley Industrial Park, 1777 Dazheng Road, East District, high tech Zone, Jinan City, Shandong Province 250000 Patentee after: Jinan Yiming Medical Technology Co.,Ltd. Address before: 100000 1 floor 125, 3 tower 538, Yongfeng Tun, Haidian District, Beijing. Patentee before: Yiming (Beijing) Cell Biotechnology Co.,Ltd. |
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CP03 | Change of name, title or address |
Address after: Room 206, building 17, Life Science City, pharmaceutical Valley Industrial Park, 1777 Dazheng Road, East Street, high tech Zone, Jinan City, Shandong Province Patentee after: Yiming (Jinan) Biotechnology Co.,Ltd. Country or region after: China Address before: Room 206, building 17, Life Science City, pharmaceutical Valley Industrial Park, 1777 Dazheng Road, East Street, high tech Zone, Jinan City, Shandong Province Patentee before: Jinan Yiming Medical Technology Co.,Ltd. Country or region before: China |