CN106075557A - A kind of liquid wound protection material formed containing nanoaperture flexible membrane - Google Patents
A kind of liquid wound protection material formed containing nanoaperture flexible membrane Download PDFInfo
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- CN106075557A CN106075557A CN201610466871.1A CN201610466871A CN106075557A CN 106075557 A CN106075557 A CN 106075557A CN 201610466871 A CN201610466871 A CN 201610466871A CN 106075557 A CN106075557 A CN 106075557A
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- protection material
- flexible membrane
- formed containing
- wound protection
- material formed
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61L—METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS IN GENERAL; DISINFECTION, STERILISATION OR DEODORISATION OF AIR; CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES; MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS OR SURGICAL ARTICLES
- A61L26/00—Chemical aspects of, or use of materials for, wound dressings or bandages in liquid, gel or powder form
- A61L26/0061—Use of materials characterised by their function or physical properties
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- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Materials Engineering (AREA)
- Epidemiology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Materials For Medical Uses (AREA)
Abstract
The invention belongs to field of medical article technology, relate to a kind of Wound protection material.A kind of liquid wound protection material formed containing nanoaperture flexible membrane, including following components in percentage by weight: celluloid 4 20%, non-drying oils and fats 2 20%, plasticiser 0.3 20%, volatile solvent 20 80%, anticorrosion and bactericidal agent 0.01 10%.The liquid wound protection material formed containing nanoaperture flexible membrane of the present invention; utilize the occupation time process of non-drying oils and fats in liquid; after volatilizer volatilizees; the waterproofing membrane of nano aperture can be had in wound surface formation; the existence of nanoaperture ensure that steam normally through thin film, thus can be protected wound and promote the healing of wound.
Description
Technical field
The invention belongs to field of medical article technology, relate to a kind of Wound protection material.
Background technology
Presently commercially available many protecting wound surface materials such as part polyethylene alcoholic product or mackintosh product water steam without
Method penetrates, and causes wound to turn white swelling, affects speed of wound healing and effect, and traditional gauze or adhesive bandage product rise not
To waterproof action, it is easily caused wound infection.Therefore, a kind of no cytotoxicity is prepared；Without sensitization；There is stronger anti-sense
Metachromia energy；The preferably the most preferable mechanical performance of physical characteristic is to be suitable for the protection of any erose wound surface；Have
The wound dressing of the exchange in suitable aperture, it is ensured that while wound surface moist environment, beneficially gas and the discharge of tissue fluid is
Current desired.
Summary of the invention
It is an object of the invention to provide a kind of Wound protection material, this material be a kind of use film former, volatile solvent,
The fluent material that non-volatile oils and fats and other compositions are mixed with, has suitable aperture, it is ensured that wound surface moist environment same
Time, the beneficially exchange of gas and the discharge of tissue fluid.
To achieve these goals, the technical solution used in the present invention is: one can be formed containing nanoaperture flexible membrane
Liquid wound protection material, including following components in percentage by weight: celluloid 4-20%, non-drying oils and fats 2-20%,
Plasticiser 0.3-20%, volatile solvent 20-80%, anticorrosion and bactericidal agent 0.01-10%.
Described non-drying oils and fats is selected from vitamin E, Vitamin E acetate, pantothenylol, Oleum Ricini, Oleum sesami, soybean oil, flower
Oil generation, isopropyl palmitate, ricinoleic acid glyceride, ethylhexyl palmitate, Adeps Bovis seu Bubali resin, stearate, alcohol benzoate, oneself
Adipate, cocoanut oil alcohol caprylate, cocoanut oil alcohol decanoin, dicaprylyl carbonate, stearic alcohol ether, isononyl isononanoate, oleyl alcohol mustard
Acid esters, Semen Myristicae bright flesh myristic acid fat, dicaprylyl ether, tetramethylolmethane four ester, hexyldecanol, hexyldecanol laurate, octanoic acid
Monooctyl ester, octyl, octanoic acid Propylheptyl, spermaceti alcohol ester, decyl oleate, hydrogenated vegetable oil glyceride, octyl dodecanol, hexyl
Decanol, octyl dodecanol myristinate, isopropyl myristate, Parleam, hydrogenation poly-certain herbaceous plants with big flowers alkene, octanoic acid glycerol three
Any one in ester, tricaprin, or the mixture that two or more arbitrary proportion mixes.
Described plasticiser is selected from glycerol, Camphora, polyvinylpyrrolidone, tributyl 2-acetylcitrate, polyvinyl alcohol contracting fourth
Any one in aldehyde, or the mixture that two or more arbitrary proportion mixes.
Described volatile solvent is selected from ethyl acetate, butyl acetate, pentyl acetate, eugenol, Essential Oil of Radix Angelicae Dahuricae, isopropyl
Any one in alcohol, ethanol, or the mixing liquid that two or more arbitrary proportion mixes.
Described anticorrosion and bactericidal agent pricks bromine selected from benzyl alcohol, hydroxyquinoline, triclosan, alkyl Benzalkonii Chloridum, benzalkonium chloride, benzene
Any one in ammonium, chlorhexidine, iodine or povidone iodine.
The described liquid wound protection material formed containing nanoaperture flexible membrane, can be at celluloid after film forming
Forming nanoscale hole between fiber, the hole average pore size formed is 0.2-30000nm.
This material can directly be packed and use as liquid adhesive bandage, or prefabricated film forming and suitably cut out molding and
Use after the subsequent treatment such as paving glue.
The liquid wound protection material formed containing nanoaperture flexible membrane of the present invention, utilizes non-drying oil in liquid
The occupation time process of fat, after volatilizer volatilizees, can have the waterproofing membrane of nano aperture, nanoaperture in wound surface formation
Existence ensure that steam normally through thin film, thus can be protected wound and promote the healing of wound.
Detailed description of the invention
Example 1: a kind of liquid wound protection material formed containing nanoaperture flexible membrane, including following weight portion
Component: celluloid 12%, isopropyl palmitate 10%, ricinoleic acid glyceride 2.5%, Camphora 0.5%, ethyl acetate 50%, acetic acid
Butyl ester 15%, benzyl alcohol 10%.
Under agitation, celluloid will be added in batches in addition to celluloid after all substances mix homogeneously
And mix homogeneously.After degassed process, subpackage also airtight keeps in Dark Place.Obtain the liquid wound that can be formed containing nanoaperture flexible membrane
Mouth protection material.
Embodiment 2, a kind of liquid wound protection material formed containing nanoaperture flexible membrane, including following weight portion
Component: celluloid 18%, vitamin E 5%, Oleum sesami 2%, Oleum Ricini 4%, stearate 2%, glycerol 5%, polyvinyl alcohol contract
Butyraldehyde 3%, pentyl acetate 15%, butyl acetate 13%, isopropanol 8%, eugenol 15%, benzalkonium bromide 10%.
Under agitation, celluloid will be added in batches in addition to celluloid after all substances mix homogeneously
And mix homogeneously.After degassed process, subpackage also airtight keeps in Dark Place.Obtain the liquid wound that can be formed containing nanoaperture flexible membrane
Mouth protection material.
Embodiment 3, a kind of liquid wound protection material formed containing nanoaperture flexible membrane, including following weight portion
Component: celluloid 20%, ethylhexyl palmitate 5%, dicaprylyl ether 5%, hexyldecanol laurate 3%, acetyl Fructus Citri Limoniae
Acid tributyl 6%, polyvinyl butyral resin 3%, pentyl acetate 10%, ethanol 8%, Essential Oil of Radix Angelicae Dahuricae 20%, isopropanol 10%, hibitane
10%。
Under agitation, celluloid will be added in batches in addition to celluloid after all substances mix homogeneously
And mix homogeneously.After degassed process, subpackage also airtight keeps in Dark Place.Obtain the liquid wound that can be formed containing nanoaperture flexible membrane
Mouth protection material.
Embodiment 4, a kind of liquid wound protection material formed containing nanoaperture flexible membrane, including following weight portion
Component: celluloid 17%, octanoic acid Propylheptyl 2%, spermaceti alcohol ester 2%, decyl oleate 1%, isononyl isononanoate 2%, oleyl alcohol
Eruciate 3%, cocoanut oil alcohol decanoin 3%, polyvinylpyrrolidone 5%, glycerol 5%, ethyl acetate 20%, Essential Oil of Radix Angelicae Dahuricae 15%, different
Propanol 15%, povidone iodine 10%.
Under agitation, celluloid will be added in batches in addition to celluloid after all substances mix homogeneously
And mix homogeneously.After degassed process, subpackage also airtight keeps in Dark Place.Obtain the liquid wound that can be formed containing nanoaperture flexible membrane
Mouth protection material.
Embodiment 5, a kind of liquid wound protection material formed containing nanoaperture flexible membrane, including following weight portion
Component: celluloid 15%, Parleam 2%, hydrogenate poly-certain herbaceous plants with big flowers alkene 5%, Trivent OCG 5%, tricaprin
3%, Camphora 5%, glycerol 5%, tributyl 2-acetylcitrate 5%, butyl acetate 18%, eugenol 12%, isopropanol 15%, ethanol 5%, hydroxyl
Base quinoline 10%.
Under agitation, celluloid will be added in batches in addition to celluloid after all substances mix homogeneously
And mix homogeneously.After degassed process, subpackage also airtight keeps in Dark Place.Obtain the liquid wound that can be formed containing nanoaperture flexible membrane
Mouth protection material.
Claims (6)
1. the liquid wound protection material that a kind can be formed containing nanoaperture flexible membrane, it is characterised in that: include following weight
The component of percentage ratio: celluloid 4-20%, non-drying oils and fats 2-20%, plasticiser 0.3-20%, volatile solvent 20-80%,
Anticorrosion and bactericidal agent 0.01-10%.
The liquid wound protection material formed containing nanoaperture flexible membrane the most according to claim 1, its feature exists
In: described non-drying oils and fats selected from vitamin E, Vitamin E acetate, pantothenylol, Oleum Ricini, Oleum sesami, soybean oil, Oleum Arachidis hypogaeae semen,
Isopropyl palmitate, ricinoleic acid glyceride, ethylhexyl palmitate, Adeps Bovis seu Bubali resin, stearate, alcohol benzoate, adipic acid
Dibutyl ester, cocoanut oil alcohol caprylate, cocoanut oil alcohol decanoin, dicaprylyl carbonate, stearic alcohol ether, isononyl isononanoate, oleyl alcohol eruciate,
Semen Myristicae bright flesh myristic acid fat, dicaprylyl ether, tetramethylolmethane four ester, hexyldecanol, hexyldecanol laurate, octyl octanoate,
Octyl, octanoic acid Propylheptyl, spermaceti alcohol ester, decyl oleate, hydrogenated vegetable oil glyceride, octyl dodecanol, hexyldecanol,
Octyl dodecanol myristinate, isopropyl myristate, Parleam, hydrogenation poly-certain herbaceous plants with big flowers alkene, Trivent OCG, capric acid
Any one in triglyceride, or the mixture that two or more arbitrary proportion mixes.
The liquid wound protection material formed containing nanoaperture flexible membrane the most according to claim 1, its feature exists
In: described plasticiser is in glycerol, Camphora, polyvinylpyrrolidone, tributyl 2-acetylcitrate, polyvinyl butyral resin
Any one, or the mixture that two or more arbitrary proportion mixes.
The liquid wound protection material formed containing nanoaperture flexible membrane the most according to claim 1, its feature exists
In: described volatile solvent is selected from ethyl acetate, butyl acetate, pentyl acetate, eugenol, Essential Oil of Radix Angelicae Dahuricae, isopropanol, ethanol
In any one, or the mixing liquid that two or more arbitrary proportion mixes.
The liquid wound protection material formed containing nanoaperture flexible membrane the most according to claim 1, its feature exists
In: described anticorrosion and bactericidal agent is selected from benzyl alcohol, hydroxyquinoline, triclosan, alkyl Benzalkonii Chloridum, benzalkonium chloride, benzalkonium bromide, chlorine
Any one in own fixed, iodine or povidone iodine.
6. according to the liquid wound protection material formed containing nanoaperture flexible membrane described in any one of claim 1-5,
It is characterized in that: nanoscale hole, the average hole of hole formed after material filming, can be formed between cellulose nitrate cellulose fiber
Footpath is 0.2-30000nm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610466871.1A CN106075557A (en) | 2016-06-24 | 2016-06-24 | A kind of liquid wound protection material formed containing nanoaperture flexible membrane |
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| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610466871.1A CN106075557A (en) | 2016-06-24 | 2016-06-24 | A kind of liquid wound protection material formed containing nanoaperture flexible membrane |
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| CN106075557A true CN106075557A (en) | 2016-11-09 |
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| CN201610466871.1A Pending CN106075557A (en) | 2016-06-24 | 2016-06-24 | A kind of liquid wound protection material formed containing nanoaperture flexible membrane |
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Cited By (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107412847A (en) * | 2017-07-01 | 2017-12-01 | 南京乐齐医药科技有限公司 | A kind of Wound dressing of liquid form and preparation method thereof |
| CN108578762A (en) * | 2018-05-21 | 2018-09-28 | 上海耐定工贸有限公司 | A kind of conveniently liquid bandage and preparation method thereof |
| CN108904876A (en) * | 2018-10-15 | 2018-11-30 | 长春艾迪尔医用科技发展有限公司 | A kind of liquid wound dressing and preparation method thereof |
| CN108939145A (en) * | 2018-08-13 | 2018-12-07 | 西安中天生物医药有限公司 | A kind of liquid adhesive bandage and preparation method thereof |
| CN110101900A (en) * | 2019-06-20 | 2019-08-09 | 江西高大生物医疗科技有限公司 | A kind of film forming agent of the insulation blocking surface of a wound |
| CN110898092A (en) * | 2019-11-25 | 2020-03-24 | 上海强德食品科技有限公司 | Liquid hemostatic and detumescence patch composition and preparation method thereof |
| CN110947028A (en) * | 2019-12-06 | 2020-04-03 | 通化师范学院 | Ag nano particles prepared from soybean leaching solution and preparation method of liquid adhesive bandage of Ag nano particles |
| CN112165960A (en) * | 2018-04-06 | 2021-01-01 | 佩利斯护理有限公司 | Composition for treating chronic wounds |
| CN115887747A (en) * | 2022-10-22 | 2023-04-04 | 湖南中腾湘岳生物科技有限公司 | Liquid wound protection material containing nano-pore flexible membrane and preparation method thereof |
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| CN101031280A (en) * | 2004-07-29 | 2007-09-05 | 布隆多控股有限公司 | Skin coating composition and its application |
| CN102058900A (en) * | 2010-12-13 | 2011-05-18 | 都本立 | Waterproof liquid bandage for wound surface protection and preparation method thereof |
| CN104971377A (en) * | 2015-06-23 | 2015-10-14 | 潘秀娟 | Liquid wound glue and preparation method |
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Patent Citations (4)
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| CN101031280A (en) * | 2004-07-29 | 2007-09-05 | 布隆多控股有限公司 | Skin coating composition and its application |
| CN102058900A (en) * | 2010-12-13 | 2011-05-18 | 都本立 | Waterproof liquid bandage for wound surface protection and preparation method thereof |
| CN104971377A (en) * | 2015-06-23 | 2015-10-14 | 潘秀娟 | Liquid wound glue and preparation method |
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Cited By (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN107412847A (en) * | 2017-07-01 | 2017-12-01 | 南京乐齐医药科技有限公司 | A kind of Wound dressing of liquid form and preparation method thereof |
| CN112165960A (en) * | 2018-04-06 | 2021-01-01 | 佩利斯护理有限公司 | Composition for treating chronic wounds |
| CN108578762A (en) * | 2018-05-21 | 2018-09-28 | 上海耐定工贸有限公司 | A kind of conveniently liquid bandage and preparation method thereof |
| CN108939145A (en) * | 2018-08-13 | 2018-12-07 | 西安中天生物医药有限公司 | A kind of liquid adhesive bandage and preparation method thereof |
| CN108904876A (en) * | 2018-10-15 | 2018-11-30 | 长春艾迪尔医用科技发展有限公司 | A kind of liquid wound dressing and preparation method thereof |
| CN110101900A (en) * | 2019-06-20 | 2019-08-09 | 江西高大生物医疗科技有限公司 | A kind of film forming agent of the insulation blocking surface of a wound |
| CN110898092A (en) * | 2019-11-25 | 2020-03-24 | 上海强德食品科技有限公司 | Liquid hemostatic and detumescence patch composition and preparation method thereof |
| CN110947028A (en) * | 2019-12-06 | 2020-04-03 | 通化师范学院 | Ag nano particles prepared from soybean leaching solution and preparation method of liquid adhesive bandage of Ag nano particles |
| CN115887747A (en) * | 2022-10-22 | 2023-04-04 | 湖南中腾湘岳生物科技有限公司 | Liquid wound protection material containing nano-pore flexible membrane and preparation method thereof |
| CN115887747B (en) * | 2022-10-22 | 2024-02-20 | 湖南中腾湘岳生物科技有限公司 | Liquid wound protection material containing nano-pore flexible membrane and preparation method thereof |
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| C06 | Publication | ||
| PB01 | Publication | ||
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| RJ01 | Rejection of invention patent application after publication | ||
| RJ01 | Rejection of invention patent application after publication |
Application publication date: 20161109 |