CN106075120A - A kind of Eczema Creams agent - Google Patents

A kind of Eczema Creams agent Download PDF

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Publication number
CN106075120A
CN106075120A CN201610526378.4A CN201610526378A CN106075120A CN 106075120 A CN106075120 A CN 106075120A CN 201610526378 A CN201610526378 A CN 201610526378A CN 106075120 A CN106075120 A CN 106075120A
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parts
eczema
agent
skin
purified water
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CN106075120B (en
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贾艳
诸辉
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Ningbo Xi Nuoya Marine Organisms Science And Technology Ltd
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Ningbo Xi Nuoya Marine Organisms Science And Technology Ltd
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A61K31/716—Glucans
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/25—Araliaceae (Ginseng family), e.g. ivy, aralia, schefflera or tetrapanax
    • A61K36/258—Panax (ginseng)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/32—Burseraceae (Frankincense family)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/53—Lamiaceae or Labiatae (Mint family), e.g. thyme, rosemary or lavender
    • A61K36/535—Perilla (beefsteak plant)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/61—Myrtaceae (Myrtle family), e.g. teatree or eucalyptus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/185—Magnoliopsida (dicotyledons)
    • A61K36/87—Vitaceae or Ampelidaceae (Vine or Grape family), e.g. wine grapes, muscadine or peppervine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00—Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18—Magnoliophyta (angiosperms)
    • A61K36/88—Liliopsida (monocotyledons)
    • A61K36/899—Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels

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  • Health & Medical Sciences (AREA)
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Abstract

The invention discloses the Eczema Creams agent of the dermatosis such as a kind for the treatment of eczema containing beta glucan composition, dermatitis, there is the effects such as sterilization, antiinflammatory, moisturizing and desalination pigment, combine with the composition of raw materials of natural botanical source, for fields such as skin care item, health product and medical products.Described Eczema Creams agent is made up of the raw material of following weight portion: emulsifying agent 2～6 parts, crude vegetal 5～20 parts, beta glucan 25～35 parts, Herba Portulacae extract 2～10 parts, Radix Notoginseng total arasaponins 0.1～2 parts, purified water 20～80 parts.

Description

A kind of Eczema Creams agent
Technical field
The present invention relates to a kind of pharmaceutical preparation treating dermatosis, particularly relate to a kind of treat eczema, dermatitis wet Rash ointment.
Background technology
Eczema is a kind of common anaphylaxis dermatosis, with rubescent, edema, pruritus and dry for characterize, can with incrustation, Peel off, bubble, ftracture, hemorrhage or oozing of blood, the course of disease is irregular, in recurrent exerbation, acute pruritus.Recently studying display, eczema can Infected by multiple-microorganism and cause, staphylococcus aureus, pityrosporum furfur etc. can be detected at eczema skin lesion.Treatment eczema Primary focus is sterilization, antipruritic, antiinflammatory and moisturizing.Rely primarily on glucocorticoids preparation, tar class clinically at present Preparation, immunomodulator or antibiotic external preparation treat eczema.But prolonged application hormone and antibiotic, be easily generated clinically The local untoward reaction such as drug resistance, atrophoderma, telangiectasis, pigmentation.
Chinese medicine composition or the Chinese and western medicinal composition for the treatment of eczema in prior art have disclosed, but prescription is complicated.Such as:
Publication number CN 101391000 A file discloses a kind of topical composition treating eczema and preparation method thereof, Composite formula in percentage by weight is 1%-10% Pollen Pini extract, 1%-10% Pollen Tyjphae extract and 1%- 10% Spora Lygodii extract, wherein Pollen Pini extract, Pollen Tyjphae extract and Spora Lygodii extract content in the composition is total With should be at 5%-30%, auxiliary agent includes Pulvis Talci, stearic acid, Borneolum Syntheticum, menthol, glyceryl monostearate, sodium alginate, card ripple Nurse, triethanolamine, glycerol, vegetable oil, azone etc..
Publication number CN 102861271 A file discloses externally applied anti-inflammation antipruritic ointment preparation and preparation method thereof, according to Weight ratio a combination thereof thing proportioning is Radix Sophorae Flavescentis 20-50 part, Fructus Cnidii 10-20 part, Fructus Kochiae 20-30 part, Cortex Phellodendri 20-30 part, Rhizoma Atractylodis 20-30 part, Rhizoma Smilacis Glabrae 20-40 part, dried Alumen 10-20 part, Mentholum is appropriate, and ability after needing repeatedly to extract with 70% dehydrated alcohol Can be made into.
Publication number CN 102861274 A file discloses a kind of external application Chinese medicine treating eczema, according to its group of weight ratio Compound proportioning is Radix Astragali 20-30 part, Radix Saposhnikoviae 10-20 part, Radix Cynanchi Paniculati 10-20 part, Rhizoma Atractylodis Macrocephalae (parched) 10-20 part, Herba Schizonepetae 10-20 part, hardship Ginseng 10-20 part, Semen Coicis 15-25 part, Periostracum Cicadae 10-20 part, Radix Glycyrrhizae 6-15 part, Cortex Pseudolaricis 15-25 part, Rhizoma Smilacis Glabrae 10-25 part, cnidium monnieri Sub-20-30 part, Herba Menthae 10-20 part, Radix Scutellariae 10-20 part, Cortex Dictamni 20-30 part.
Publication number CN 104706824 A file discloses a kind of Chinese medicine preparation treating eczema, according to its group of weight ratio Compound proportioning is Olibanum 8 parts, Rhizoma Atractylodis 7 parts, the Cortex Eucommiae 8 parts, Cortex Dictamni 5 parts, Radix Polygalae 18 parts, Fructus Cnidii 5 parts, Folium Isatidis 3 parts, gold silver Spend 8 parts, Semen Plantaginis 0.5 part.
Summary of the invention
The present invention provides a kind of eczema ointment treating the dermatosis such as eczema, dermatitis, with natural materials source for raw material system Becoming, formula combination is simple, it is possible to sterilization, antipruritic, antiinflammatory and moisturizing, and has antiallergic and repair the effect of impaired skin, Performance is gentle, non-stimulated to skin, have no side effect, do not produce drug resistance, easy to use and environmental protection, is particularly well-suited to motherhood Woman, infant and high-risk sensitive group.
For achieving the above object, the technical solution used in the present invention is: a kind of Eczema Creams agent containing beta glucan, including Following raw material:
Beta glucan 25-35 part, Herba Portulacae extract 2-10 part, Radix Notoginseng total arasaponins 0.1-2 part, crude vegetal 5-20 Part, emulsifying agent 2-6 part, purified water 20-80 part.
Described emulsifying agent is formulated by described weight portion by following three kinds of raw materials: cetearyl alcohol 0.5-3 part, spermaceti Stearyl glucoside 1-5 part, glyceryl monostearate 1-6 part.
Described crude vegetal by following six kinds of raw materials any two to five kinds formulated with following weight portion:
Shea butter 0.1～8 parts；
Semen Tritici aestivi germ oil 0.1～8 parts；
Oleum Vitis viniferae 0.1～8 parts；
Oleum Caryophylli 0.1～8 parts；
Olive oil 0.1～8 parts；
Perilla oil 0.1～8 parts.
Preferably, described purified water is distilled water or deionized water.
The present invention uses the beneficial effect of aforementioned schemes and the advantage to be:
1. raw material described in, with natural materials for source, gentle can act on skin after certain proportioning non-stimulatedly, Play sterilization, antipruritic, antiinflammatory and effect of moisturizing.
Wherein:
Beta glucan is with 1, and 3 glycosidic bonds are main chain, and 1,6 glycosidic bond is the naturally occurring polysaccharide of side chain, with patent Method described in application number 201510725996.7 file obtains, i.e. by Schizophyllum commune Franch． fermented extracted.Skin can be improved thin The multiplication rate of born of the same parents, promotes collagen protein and the generation of elastin laminin, helps to update and repair impaired skin, promotes healing of cicatrix Close；Keep moisture of skin, improve the moisturizing degree of skin and the smoothness that compacts；Suppression histamine release of mast cell and de-effectively Grain effect, sensitive skin of releiving, reduces chafing.
Herba Portulacae extract is the stem from Herba Portulacae and leaf, the bioactive substance obtained with low-temperature extraction method, molten Solution prepares in the butanediol solution of 39.5%, has broad-spectrum antiseptic and antiinflammatory, anti-allergic effects, and can promote epithelial cell Physiological function is replied.
Radix Notoginseng total arasaponins is the effective ingredient extracting separation from high-quality Radix Notoginseng, including more than 20 kinds of saponin active substances, 17 Plant trace element, albumen, abundant vitamin, polysaccharide etc., there is removing free radical, antiinflammatory, antioxidation, improve local skin The blood circulation of skin and metabolism, strengthen the immunity of skin, accelerating wound healing, repair the impaired skin of inflammation.
Shea butter has the effect promoting skin regeneration, preventing photoaging, to the skin suffering from dermatitis, sunburn and scar Have and significantly promote Healing.The top layer of skin there are the most long-term moistening effect, its spreadability and percutaneous absorbability Fairly the best, it is particularly well-suited to without greasy formula, stimulation of releiving, moisten epidermal area.
Semen Tritici aestivi germ oil contains abundant vitamin E and vitamin B complex, and vitamin E has holding moisture, skin of moistening Function, the lipid in protection Skin Cell film and protein so that it is play the effect being combined with moisture, maintain the normal generation of cell Thank, and the microcirculation of skin can be improved, strengthen the immunity of skin；Vitamin B complex includes vitamin B1, B2, B6 etc., is to constitute The component of the necessary protease of skin metabolism, simultaneously can activated epithelial, antiinflammatory moisturizing, alleviate pachylosis situation.
Oleum Vitis viniferae can promote the appropriately crosslinked of collagen protein with skin nutrition cell, prevent skin from wrinkle and capsule occur Bubble, and the coarse and keratinization of skin, and there is the effect removing free radical, accelerate skin metabolism, protect epiderm skin Cell and regenerative cell；Keep moisture of skin, and oily oiliness skin-friendly is strong, is easily absorbed by the skin, be suitable for various skin and use.
The medical value of Oleum Caryophylli is mainly embodied by eugenol, the polar group on aromatic rings in its chemical constitution, energy The active group of some enzyme is combined in microorganism, destroys the normal metabolic function of microorganism, reaches to suppress fungus, the work of antibacterial With.Oleum Caryophylli can promote Drug Percutaneous Absorption.
Vitamin kind and quantity relatively other oils contained by olive oil substantially want many, as wherein vitamin A (and A is former) has Having and make skin smooth, delicacy and increase the effect of its elasticity, vitamin B1 has the function flattening skin fine corrugations, vitamin C has enhancing vessel wall elasticity, expands the effects such as blood flow.
Rich in alpha-linolenic acid in perilla oil, alpha-linolenic acid has Platelet Activating Factor and the work of leukotriene generation With, thus there is effect of anti-allergic inflammation.
Choosing above-mentioned crude vegetal is cream base, it is possible to makes full use of crude vegetal and disappears skin moisture-keeping sterilization The effects such as scorching, promotion skin injury healing, auxiliary Main Ingredients and Appearance plays drug effect.
2. the raw material that the present invention uses obtains simplicity, and Herba Portulacae extract and Radix Notoginseng total arasaponins are all commercially available, Beta glucan belongs to a kind of extracellular polysaccharide, originates various, such as Lentinus Edodes, Schizophyllum commune Franch．, Ganoderma, yeast etc., to split pleat in the present invention Bacterium is as the source strain of beta glucan, i.e. by Schizophyllum commune Franch． fermented extracted.Schizophyllum commune Franch． is wide at China's distributional region, strain Resource is the abundantest.Main Ingredients and Appearance formula of the present invention is simple, takes 3 kinds of raw material prescriptions to be formed.Therefore before there is scale application Scape.
Detailed description of the invention
Describe embodiments of the present invention in detail below with reference to specific embodiment, whereby how the present invention is applied skill Art means solve technical problem, and the process that realizes reaching technique effect can fully understand and implement according to this.
If not specializing, the conventional hands that the technological means employed in embodiment is well known to those skilled in the art Section, the reagent used and product are also available commercial.The source of agents useful for same, trade name and be necessary to list it Constituent person, all indicates when occurring first.
Embodiment one
A kind of Eczema Creams agent, including following raw material:
Beta glucan 25 parts
Herba Portulacae extract 2 parts
Radix Notoginseng total arasaponins 0.2 part
Semen Tritici aestivi germ oil 3 parts
Oleum Vitis viniferae 3 parts
Cetearyl alcohol 0.5 part
Cetearyl glucoside 1 part
Glyceryl monostearate 1 part
Distilled water 30 parts
Embodiment two
A kind of Eczema Creams agent, including following raw material:
Beta glucan 35 parts
Herba Portulacae extract 8 parts
Radix Notoginseng total arasaponins 1 part
Shea butter 5 parts
Semen Tritici aestivi germ oil 2 parts
Oleum Vitis viniferae 3 parts
8 parts of olive oil
Perilla oil 0.5 part
Cetearyl alcohol 2 parts
Cetearyl glucoside 3 parts
Glyceryl monostearate 1 part
Distilled water 80 parts
Embodiment three
A kind of Eczema Creams agent, including following raw material:
Beta glucan 28 parts
Herba Portulacae extract 3 parts
Radix Notoginseng total arasaponins 0.3 part
Semen Tritici aestivi germ oil 2.5 parts
Oleum Caryophylli 0.5 part
4 parts of olive oil
Cetearyl alcohol 0.6 part
Cetearyl glucoside 1 part
Glyceryl monostearate 1 part
Distilled water 40 parts
Embodiment four
A kind of Eczema Creams agent, including following raw material:
Beta glucan 32 parts
Herba Portulacae extract 6 parts
Radix Notoginseng total arasaponins 0.8 part
Shea butter 4 parts
Semen Tritici aestivi germ oil 4 parts
Perilla oil 3 parts
Cetearyl alcohol 2 parts
Cetearyl glucoside 1 part
Glyceryl monostearate 1 part
Deionized water 60 parts
Embodiment five
A kind of Eczema Creams agent, including following raw material:
Beta glucan 30 parts
Herba Portulacae extract 5 parts
Radix Notoginseng total arasaponins 0.5 part
Shea butter 3 parts
Oleum Vitis viniferae 1 part
3 parts of olive oil
Perilla oil 2 parts
Cetearyl alcohol 0.6 part
Cetearyl glucoside part 1.3 parts
Glyceryl monostearate 1 part
Deionized water 52.5 parts
The present embodiment is optimal case of the present invention.
Drug test
The present invention has carried out animal experiment about inflammatory symptom inhibitory action and skin irritation.Research process is as follows:
Test material: white mice, 18～22g, male and female half and half；Rat, 160～180g, male and female half and half.
Medicine and reagent: eczema ointment, dimethylbenzene, vaseline
Research method 1: the impact of xylol induced mice auricle edema
Take 18～22g Kunming mouse 30, be randomly divided into two groups, often group 15, male and female half and half, respectively matched group, Eczema ointment group, matched group is coated with excipient (vaseline), and remaining group is coated with relative medicine respectively in mouse right ear, 0.5g/, often Days 2 times, for three days on end, after the 4th day coating 1 hour each group wash away medicine with distilled water, clean with dry cotton ball.Respectively organize mice Auris dextra is only coated with dimethylbenzene 0.05ml/, and left ear compares, and puts to death animal after 30 minutes, with 8mm card punch, mice left and right ear is same Cut Deng position homalographic, with scales/electronic balance weighing, with the difference of left and right auricle weight as swelling, calculate each group of swelling, ask Go out inhibitory rate of intumesce, result such as following table:
Note: compare with matched group, * p < 0.05
Result shows, eczema ointment can substantially alleviate dimethylbenzene induced mice ear swelling degree, has mice ear inflammation Obvious inhibiting effect.
Research method 2: the local excitation to rat intact skin is tested
Take rat 10, go to 2 pieces, hair-fields what spinal column both sides, back curved scissors cut 2.5cm x 2.5cm, note not damaging Hinder skin.Test Shi Meikuai unhairing district is coated with 0.5g eczema ointment and 0.5g substrate (vaseline), respectively with one layer of oilpaper and bilayer Immobilization with adhesive tape after gauze covering.With scrub water after 24 hours, remove remaining ointment and vaseline, observe and remove after left drug 1 Hour, 24 hours, 48 hours and the skin wound repair (coating position is with or without erythema, edema) of 72 hours, be integrated evaluate As a result, respectively going hair-fields skin to have no the irritant reaction such as erythema, edema, integrated value is 0.Show eczema ointment to rat intact skin without Zest.

Claims (6)

1. an Eczema Creams agent, it is characterised in that include following weight parts raw material:
Beta glucan 25-35 part, Herba Portulacae extract 2-10 part, Radix Notoginseng total arasaponins 0.1-2 part, crude vegetal 5-20 part, breast Agent 2-6 part, purified water 20-80 part.
Eczema Creams agent the most according to claim 1, it is characterised in that described emulsifying agent is pressed described by following three kinds of raw materials Weight portion is formulated: cetearyl alcohol 0.5-3 part, cetearyl glucoside 1-5 part, glyceryl monostearate 1-6 part.
Eczema Creams agent the most according to claim 1, it is characterised in that described crude vegetal is by following six kinds of raw materials Any two to five kinds formulated with following weight portion:
Shea butter 0.1～8 parts；
Semen Tritici aestivi germ oil 0.1～8 parts；
Oleum Vitis viniferae 0.1～8 parts；
Oleum Caryophylli 0.1～8 parts；
Olive oil 0.1～8 parts；
Perilla oil 0.1～8 parts.
Eczema Creams agent the most according to claim 1, it is characterised in that: described purified water is distilled water or deionized water.
Eczema Creams agent the most according to claim 1, it is characterised in that: in parts by weight, it preferably includes following raw material: Beta glucan 28-32 part, Herba Portulacae extract 3-7 part, Radix Notoginseng total arasaponins 0.3-0.8 part, crude vegetal 7-12 part, emulsifying agent 2-4 part, purified water 40-60 part.
Eczema Creams agent the most according to claim 1, it is characterised in that: in parts by weight, optimization formula combination include β- Glucosan 30 parts, Herba Portulacae extract 5 parts, Radix Notoginseng total arasaponins 0.5 part, shea butter 3 parts, Oleum Vitis viniferae 1 part, 3 parts of olive oil, Perilla oil 2 parts, cetearyl alcohol 0.6 part, cetearyl glucoside 1.3 parts, glyceryl monostearate 1 part, purified water 52.5 Part.
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Cited By (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107096017A (en) * 2017-06-27 2017-08-29 成都斌能节能环保科技有限公司 Treat dermopathic external medicine composition and its application method
CN109010403A (en) * 2018-10-24 2018-12-18 王秀国 A kind of health care eczema ointment
CN109125146A (en) * 2018-11-06 2019-01-04 南京中医药大学 The composition and its application in cosmetics of a kind of ganoderma lucidum polysaccharide and caryophyllus oil
CN110025569A (en) * 2019-05-16 2019-07-19 吉林农业科技学院 A kind of Polysaccharide from Portulaca oleracea emulsifiable paste and preparation method thereof
CN110769836A (en) * 2018-05-23 2020-02-07 浙江立恩生物科技有限公司 Biological polysaccharide for preventing and treating acne and hormone-dependent dermatitis and application thereof
CN111713625A (en) * 2020-06-12 2020-09-29 江苏微康生物科技有限公司 Bacillus coagulans solid beverage with efficacy of relieving eczema and preparation method thereof
CN111973620A (en) * 2019-05-21 2020-11-24 浙江立恩生物科技有限公司 Biological polysaccharide for preventing and treating hormone-dependent dermatitis and application thereof
US20210393720A1 (en) * 2020-05-29 2021-12-23 Edmund Waller Hair Growth Compositions
CN114432380A (en) * 2022-02-25 2022-05-06 李楠 Traditional Chinese medicine and probiotic composition of cream for treating eczema and preparation process of traditional Chinese medicine and probiotic composition
CN115737474A (en) * 2022-08-30 2023-03-07 江苏长泰药业有限公司 Preparation method of glucan emulsion, composition containing glucan emulsion and application of composition

Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1327828A (en) * 2001-06-12 2001-12-26 马永明 Adhesive bandage able to relieve inflammation, astringe and grow muscle and its preparing process
CN1771969A (en) * 2005-10-31 2006-05-17 西安交大科技园博源生物医药有限责任公司 Externally applied emulsion for treating dermatitis and eczema
CN103385905A (en) * 2013-08-17 2013-11-13 福建医科大学附属第一医院 Compound external traditional Chinese medicinal preparation for treating eczematous dermatitis diseases
CN105255964A (en) * 2015-10-30 2016-01-20 宁波希诺亚海洋生物科技有限公司 Production method of beta-glucan

Patent Citations (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1327828A (en) * 2001-06-12 2001-12-26 马永明 Adhesive bandage able to relieve inflammation, astringe and grow muscle and its preparing process
CN1771969A (en) * 2005-10-31 2006-05-17 西安交大科技园博源生物医药有限责任公司 Externally applied emulsion for treating dermatitis and eczema
CN103385905A (en) * 2013-08-17 2013-11-13 福建医科大学附属第一医院 Compound external traditional Chinese medicinal preparation for treating eczematous dermatitis diseases
CN105255964A (en) * 2015-10-30 2016-01-20 宁波希诺亚海洋生物科技有限公司 Production method of beta-glucan

Non-Patent Citations (7)

* Cited by examiner, † Cited by third party
Title
吴艳等: "含马齿苋及牛油果树提取物护肤品对乏脂性湿疹临床效果观察", 《临床皮肤科杂志》 *
宋烈昌等: "三七总皂甙镇痛抗炎作用的实验观察", 《云南植物研究》 *
李淑慧等: "三七总皂苷抗炎作用机制的实验研究", 《中草药》 *
王国玉等: "马齿苋水提取物抗炎作用研究", 《河北医学》 *
葛一漫等: "马齿苋提取物对湿疹大鼠皮肤炎症肿胀度影响的研究", 《中国民族民间医药》 *
蔡成岗等: "β-葡聚糖结构功能与开发研究进展", 《农产品加工.学刊》 *
高天文等: "《西京皮肤科临床工作手册》", 31 August 2012, 第四军医大学出版社 *

Cited By (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107096017A (en) * 2017-06-27 2017-08-29 成都斌能节能环保科技有限公司 Treat dermopathic external medicine composition and its application method
CN110769836A (en) * 2018-05-23 2020-02-07 浙江立恩生物科技有限公司 Biological polysaccharide for preventing and treating acne and hormone-dependent dermatitis and application thereof
CN109010403A (en) * 2018-10-24 2018-12-18 王秀国 A kind of health care eczema ointment
CN109125146A (en) * 2018-11-06 2019-01-04 南京中医药大学 The composition and its application in cosmetics of a kind of ganoderma lucidum polysaccharide and caryophyllus oil
CN110025569A (en) * 2019-05-16 2019-07-19 吉林农业科技学院 A kind of Polysaccharide from Portulaca oleracea emulsifiable paste and preparation method thereof
CN111973620A (en) * 2019-05-21 2020-11-24 浙江立恩生物科技有限公司 Biological polysaccharide for preventing and treating hormone-dependent dermatitis and application thereof
WO2020233681A1 (en) * 2019-05-21 2020-11-26 浙江立恩生物科技有限公司 Biological polysaccharide having effect of preventing and treating hormone-dependent dermatitis and application thereof
CN113840613A (en) * 2019-05-21 2021-12-24 浙江立恩生物科技有限公司 Biological polysaccharide with effects of preventing and treating hormone-dependent dermatitis and application thereof
CN111973620B (en) * 2019-05-21 2024-04-16 浙江立恩生物科技有限公司 Biological polysaccharide for preventing and treating hormone-dependent dermatitis and application thereof
US20210393720A1 (en) * 2020-05-29 2021-12-23 Edmund Waller Hair Growth Compositions
CN111713625A (en) * 2020-06-12 2020-09-29 江苏微康生物科技有限公司 Bacillus coagulans solid beverage with efficacy of relieving eczema and preparation method thereof
CN114432380A (en) * 2022-02-25 2022-05-06 李楠 Traditional Chinese medicine and probiotic composition of cream for treating eczema and preparation process of traditional Chinese medicine and probiotic composition
CN115737474A (en) * 2022-08-30 2023-03-07 江苏长泰药业有限公司 Preparation method of glucan emulsion, composition containing glucan emulsion and application of composition
CN115737474B (en) * 2022-08-30 2023-11-10 江苏长泰药业股份有限公司 Preparation method of glucan emulsion, composition containing glucan emulsion and application of composition

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