CN106073768A - The non-invasive detection of human cortical brain's electroneurographic signal high sensitivity and analysis process system - Google Patents
The non-invasive detection of human cortical brain's electroneurographic signal high sensitivity and analysis process system Download PDFInfo
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- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
- A61B5/369—Electroencephalography [EEG]
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- A61B5/25—Bioelectric electrodes therefor
- A61B5/279—Bioelectric electrodes therefor specially adapted for particular uses
- A61B5/291—Bioelectric electrodes therefor specially adapted for particular uses for electroencephalography [EEG]
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- A—HUMAN NECESSITIES
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- A61B5/00—Measuring for diagnostic purposes; Identification of persons
- A61B5/24—Detecting, measuring or recording bioelectric or biomagnetic signals of the body or parts thereof
- A61B5/316—Modalities, i.e. specific diagnostic methods
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Abstract
The present invention relates to a kind of human cortical brain's non-invasive detection of electroneurographic signal high sensitivity and analysis process system, its technical characteristics is: include full electromagnetic shielding bus transfer electrode cap, data bus interface signal amplifier, analog-digital converter and computer；Being provided with multiple full electromagnetic shieldings short matrix self-aiming on full electromagnetic shielding bus transfer electrode cap and self-deploy scalp microelectrode array module, full electromagnetic shielding short matrix self-aiming self-deploys scalp microelectrode array module and is self-deployed scalp microelectrode by multiple full electromagnetic shielding self-aimings and constitute by certain matrix arrangement；Computer is analyzed processing by the internal real-time analysis process system of signal data.The present invention is reasonable in design, provides a kind of solution easy, feasible, accurate, reliable for the foundation of non-invasive people's brain computer interfaces, have reasonable in design, easy and simple to handle, capacity of resisting disturbance strong, noinvasive, accurately, the feature such as in real time.
Description
Technical field
The invention belongs to human cortical brain's electroneurographic signal detection technique field, especially a kind of human cortical brain's electroneurographic signal
The non-invasive detection of high sensitivity and analysis process system.
Background technology
At present, the diagnosis to some disease still relies on EEG (electrocardiogram) examination clinically, but EEG (electrocardiogram) examination precision and sensitive
Degree is subject to the decay in the signal attenuation such as electrode material restriction causes, signal of telecommunication transmittance process, external environment electromagnetic interference, information
The restriction of the many factors such as analysis means, causes the EEG signals details of acquisition lack, precision and real-time reduction；And electroencephalogram
In inspection scalp electrode lay and wiring is the most loaded down with trivial details, scalp electrode is easily subject to the impact such as hair, scalp oils and fats, dirt
And affect precision.The most relatively advanced magneticencephalogram inspection, can detect the atomic weak brain magnetic wave of cranium brain, but, because inspection
Look into environmental requirement harshness and inspection fee costliness still can not be popularized.In terms of scientific research, people's brain computer interfaces has become as generation
The problem of boundary's research in extensive range, and human brain Computer Interface Technology it is crucial that how to obtain high accuracy, high sensitivity and reality
Time EEG signals, at present conventional method does not all obtain preferable effect, has breakthrough to obtain human cortical brain's signal of telecommunication
Method mostly be implant electrode or microchip in brain, but these methods are invasive, owing to people's brain surgery exists greatly
Risk, all these methods, at present also in animal experiment stage, want to be generalized to clinic and also need to the longer time.
Summary of the invention
In place of it is an object of the invention to make up the deficiencies in the prior art, it is provided that a kind of reasonable in design, easy and simple to handle, anti-dry
Ability of disturbing is strong, noinvasive, accurate, real-time human cortical brain's non-invasive detection of electroneurographic signal high sensitivity and analysis process system.
The present invention solves it and technical problem is that and take techniques below scheme to realize:
A kind of human cortical brain's non-invasive detection of electroneurographic signal high sensitivity and analysis process system, including full electromagnetic shielding
Bus transfer electrode cap, data bus interface signal amplifier, analog-digital converter and computer；Described full electromagnetic shielding bus passes
On transmission of electricity polar cap, multiple full electromagnetic shieldings short matrix self-aiming is installed and self-deploys scalp microelectrode array module, described full electromagnetism
Shield short matrix self-aiming to self-deploy scalp microelectrode array module and self-deployed the micro-electricity of scalp by multiple full electromagnetic shielding self-aimings
Pole is constituted by certain matrix arrangement；Described full electromagnetic shielding short matrix self-aiming self-deploys scalp microelectrode array module at scalp
Surface detection gathers the signal of telecommunication that human cortical brain's electrical activity maps mutually in scalp surface, by full electromagnetic shielding bus transfer electrode
Cap transmits to data bus interface signal amplifier, data bus interface signal amplifier amplify and be transferred to after analog digital conversion
Computer, computer is analyzed processing by the internal real-time analysis process system of signal data.
Described full electromagnetic shielding bus transfer electrode cap includes electrode cap modular interface slot, electrode cap main body and electrode
Cap bus cable, multiple electrode cap modular interface slots are arranged in electrode cap body surfaces, at electrode cap modular interface
Full electromagnetic shielding short matrix self-aiming is installed in slot and self-deploys scalp microelectrode array module, described electrode cap bus cable
One end be connected with each electrode cap modular interface slot respectively, the other end of this electrode cap bus cable and data/address bus
Interface signal amplifier is connected.
Described electrode cap main body lower end is also equipped with Liang Ge ear hollow out forms, two arrays of electrodes cap frenulum, and Liang Ge ear engraves
Empty forms are arranged on the left and right sides of electrode cap main body lower end for pressing from both sides normal electrode, the upper end of two arrays of electrodes cap frenulum in ear
Installing electrode cap main body lower end, the lower end of electrode cap frenulum and electrode cap frenulum are fastened snap close and are linked together.
Described full electromagnetic shielding short matrix self-aiming self-deploys scalp microelectrode array module and includes microelectrode array module
Matrix part, electrode wires collect plug, full electromagnetic shielding self-aiming self-deploys scalp microelectrode and microelectrode array module matrix part
Interconnector；Full electromagnetic shielding self-aiming self-deploys in scalp microelectrode is inlaid in microelectrode array module matrix part and arranges in array
In the multiple cylindrical hole slot of row and collect plug by microelectrode array module matrix part interconnector with electrode wires to be connected,
Described electrode wires collects plug and is arranged on the side of microelectrode array module matrix part, collects in electrode wires and is provided with conduction on plug
Terminal, this electrode wires collects plug for being connected with the electrode cap modular interface slot of full electromagnetic shielding bus transfer electrode cap
Connect.
Described electrode wires collects plug and microelectrode array module matrix part interconnector all uses electromagnetic armouring structure.
Described electrode cap modular interface slot is provided with the socket in electrode cap modular interface slot, microelectrode array
Module matrix part is inlaid in electrode cap modular interface slot, and the electrode wires in microelectrode array module collects plug and electrode
Socket in hat cone massing interface slot is installed together, the socket extraction electrode cap in each electrode cap modular interface slot
Interconnector collects composition electrode cap bus cable.
Socket in described electrode cap modular interface slot, electrode cap interconnector, electrode cap bus cable all use
Electromagnetic armouring structure.
Described full electromagnetic shielding self-aiming self-deploy scalp microelectrode include electrode column, flexible deployable electro-insulating rubber post,
Cylindrical helical spring, electrode column trocar sheath, electrode wires, electro-insulating rubber pipe, deployable Graphene flexible conductive film and electromagnetic screen
Cover rubber；Described electrode column surface-coated has Graphene coating and is sleeved on electrode column trocar sheath and the deployable electro-insulating rubber of flexibility
In post, the flexible upper end of deployable electro-insulating rubber post is connected fixing with the lower end of electrode column trocar sheath, under this electro-insulating rubber post
End is connected fixing with electrode column head；The bottom of described electrode wires is connected with the upper end of electrode column, is wrapped with in electrode wires
Insulating barrier and electro-magnetic screen layer, electrode wires is fixed by being arranged on the electro-insulating rubber pipe of electrode column outer sleeve upper；Described
Deployable Graphene flexible conductive film covers the rear surface at flexible deployable electro-insulating rubber post, and is connected with electrode column head
And mutually conduct electricity；Stating the top parcel electrode column trocar sheath of electromagnetic shield rubber, flexible deployable electro-insulating rubber post is wrapped up in bottom
Top.
Described electrode column uses the good argent of electric conductivity as main material, and this electrode column head is blunt round hemisphere
Shape, this electrode column main body is cylinder, is provided with stop retainer ring for limiting electrode column relative to electrode in electrode column main body
The range of movement of post trocar sheath also stops cylindrical helical spring.
Described electrode column trocar sheath is drum-shaped hard ambroin pipe, is provided with annulus, middle circle in electrode column trocar sheath
Ring and lower annulus, on this, annulus is used for fixed insulation rubber tube extraction electrode line, and in this, annulus is used for supporting electrode column slip
And limiting spring, this lower annulus is used for supporting electrode column and slides and limit its downward range of motion.
Advantages of the present invention and good effect be:
1, that short for full electromagnetic shielding matrix self-aiming self-deploys scalp microelectrode array module, modular interface is complete for the present invention
Electromagnetic shielding bus transfer electrode cap, data bus interface signal amplifier, analog-digital converter, computer structure altogether, in real time
Detect collection human cortical brain's electrical activity in micro-electromagnetic signal of scalp surface phase mapping area and to be amplified also numeral conversion, lead to
Crossing computer the data collected are analyzed in real time and processed, the scalp microelectrode in system can be avoided hair and guide voluntarily to scalp
Surface, electrode head can prolong scalp surface expansion voluntarily thus increase effective contact area of electrode and scalp, and electrode uses and leads
The most excellent grapheme material of electrical property also uses full design of Electromagnetic Shielding by the system before analog-digital converter, thus ensures
The intensity of the signal collected and precision.
2, the full electromagnetic shielding self-conductance of the present invention consists of short quoted from extension Graphene scalp microelectrode group dense arrangement
Matrix array module, can catch scope and the change of corresponding cortex electrical activity more subtly.The full electromagnetism of modular interface
Mask bus transmission electrode cap uses quoted from extension Graphene scalp microelectrode array module with the short matrix self-conductance of full electromagnetic shielding
Modular interface design carries out grafting and uses bus design to be connected with background devices, and examiner can be that those who are investigated quickly pacify
Dress scalp microelectrode also connects background devices.
3, the present invention uses modular interface to design, can according to check or experiment need increase scalp microelectrode array
The module that module or replacing damage, thus reduce plant maintenance and maintenance cost.The data collected are carried out real-time by computer
Analyze and process, and result is stored, exports to the analysis for deliberation of the equipment specified or port and application.Collected data
Also can be utilized by a part of existing electroencephalogramsignal signal analyzing software by integrating.
4, the present invention be research human cortical brain's bioelectrical activity, the early stage of some department of neurology systemic diseases and Precise Diagnosis,
And the foundation of non-invasive people's brain computer interfaces provides a kind of solution easy, feasible, accurate, reliable, have and set
Count that reasonable, easy and simple to handle, capacity of resisting disturbance is strong, noinvasive, accurately, the feature such as in real time.
Accompanying drawing explanation
Fig. 1 is the system connection diagram of the present invention；
Fig. 2 is the structural representation that full electromagnetic shielding self-aiming self-deploys scalp microelectrode；
Fig. 3 is that full electromagnetic shielding self-aiming self-deploys structural representation after the expansion of scalp microelectrode；
Fig. 4 is the schematic three dimensional views that full electromagnetic shielding self-aiming self-deploys scalp microelectrode；
Fig. 5 is the three-dimensional perspective schematic diagram that full electromagnetic shielding short matrix self-aiming self-deploys scalp microelectrode array module；
Fig. 6 is the interconnector schematic diagram that full electromagnetic shielding short matrix self-aiming self-deploys scalp microelectrode array module；
Fig. 7 is the schematic three dimensional views that full electromagnetic shielding short matrix self-aiming self-deploys scalp microelectrode array module；
Fig. 8 is the structural representation of modular interface full electromagnetic shielding bus transfer electrode cap；
Fig. 9 is the structural representation (being not inserted into scalp microelectrode array module) of electrode cap modular interface；
Figure 10 is the structural representation (having inserted scalp microelectrode array module) of electrode cap modular interface；
Figure 11 is the circuit system block diagram of the present invention；
Figure 12 is that microelectrode array tridimensional model figure compares figure with two dimensional surface；
Figure 13 is microelectrode array transient potential D prism map；
Figure 14 is microelectrode array transient potential X-Y scheme；
Figure 15 is the software processes block diagram of computer.
Detailed description of the invention
Below in conjunction with accompanying drawing, the embodiment of the present invention is further described:
A kind of human cortical brain's non-invasive detection of electroneurographic signal high sensitivity and analysis process system, as it is shown in figure 1, include
Modular interface full electromagnetic shielding bus transfer electrode cap, data bus interface signal amplifier, analog-digital converter and computer.
Multiple full electromagnetic shieldings short matrix self-aiming is installed on described modular interface full electromagnetic shielding bus transfer electrode cap bootstrap
Beginning skin microelectrode array module, described full electromagnetic shielding short matrix self-aiming self-deploys scalp microelectrode array module by full electricity
Magnetic shield self-aiming self-deploys scalp microelectrode and constitutes by certain matrix arrangement.Described full electromagnetic shielding short matrix self-aiming is bootstrapped
Beginning skin microelectrode array module gathers, in scalp surface detection, the signal of telecommunication that human cortical brain's electrical activity maps mutually in scalp surface,
Transmitted to data bus interface signal amplifier by the data bus interface of full electromagnetic shielding bus transfer electrode cap, by signal
Amplifier amplifies and is transferred to computer after analog digital conversion.Signal data is installed in computer and analyzes and processes system in real time
System, computer to collected data by automatically analyzing in real time, process, and result is stored, output to the equipment specified or
Port is for deliberation, analyze and apply.Below each several part in system is illustrated respectively:
As shown in Figures 2 to 4, described full electromagnetic shielding self-aiming self-deploys scalp microelectrode and includes electrode column 1-1, electrode
Post surface Graphene coating 1-2, flexible deployable electro-insulating rubber post 1-3, cylindrical helical spring 1-4, electrode column trocar sheath 1-
5, electrode wires 1-6, the insulating barrier of electrode wires core outer wrap and electro-magnetic screen layer 1-7, electro-insulating rubber pipe 1-8, deployable stone
Ink alkene flexible conductive film 1-9 and electromagnetic shield rubber 1-10.Below the various piece of scalp microelectrode is illustrated respectively:
Electrode column 1-1: using the argent that electric conductivity is good as main material, this electrode column head 1-a is blunt circle
Hemispherical, electrode column main body 1-b is cylinder, is provided with stop retainer ring 1-c, this stop retainer ring in electrode column main body 1-b
1-c relative to the range of movement of electrode column trocar sheath and stops cylindrical helical spring 1-4 for limiting electrode column；At electrode column
It is that flexible deployable electro-insulating rubber post launches guide portion 1-d between lower end and the electrode column head of main body.
Electrode column surface Graphene coating 1-2: be coated on electrode column surface, this electrode column surface Graphene coating has
Good electric conductivity.
Flexible deployable electro-insulating rubber post 1-3: the most thinning, outside the upper end of this electro-insulating rubber post is with electrode column
The lower end of sleeve pipe connects fixing, and the lower end of this electro-insulating rubber post is connected fixing with electrode column head.
Cylindrical helical spring 1-4: be arranged in electrode column trocar sheath, it is fixed that its lower end is blocked retainer ring, its upper end quilt
Electrode column trocar sheath limits.
Electrode column trocar sheath 1-5: for drum-shaped hard ambroin pipe, be used for supporting electrode column along the electrode column trocar sheath longitudinal axis
Slide in direction, the bottom of electrode column trocar sheath and flexibility deployable electro-insulating rubber post 1-3 compact siro spinning technology.This electrode column trocar sheath sets
Having upper annulus 1-e, middle annulus 1-f, lower annulus 1-g, wherein, upper annulus is used for fixed insulation rubber tube 1-8 extraction electrode line,
Middle annulus is used for supporting electrode column and slides and limit spring, and lower annulus is used for supporting electrode column and slides and limit it and move downward model
Enclose, in electrode column trocar sheath, form an an electrode wires surge bunker 1-h and spring-compressed storehouse 1-i.
Electrode wires 1-6: use the metal materials such as high conductive silver to be arranged in electrode column trocar sheath 1-5, bottom it
It is connected with the upper end of electrode column；
Insulating barrier and electro-magnetic screen layer 1-7: be wrapped in outside electrode wires core.
Electro-insulating rubber pipe 1-8: for fixing and from the upper annulus extraction electrode line of electrode column trocar sheath 1-5.
Deployable Graphene flexible conductive film 1-9: cover the rear surface at flexible deployable electro-insulating rubber post 1-3, and
Being connected with electrode column head and mutually conduct electricity, after expansion, electrode in the form of annular discs and scalp are in close contact, increase scalp microelectrode with
Scalp contact area.
Electromagnetic shield rubber 1-10: rubber is internal has good electromagnetic shielding action containing metallic particles such as silver, stops
The outside electromagnetic interference between electromagnetic shielding interference and microelectrode.The top parcel electrode column overcoat of electromagnetic shield rubber 1-10
Pipe, flexible deployable electro-insulating rubber post 1-3 top is wrapped up in bottom, when flexible deployable electro-insulating rubber post 1-3 deforms unfolded
After, maskable external electromagnetic interference is to deployable Graphene flexible conductive film electrode influences.
Whole full electromagnetic shielding self-aiming self-deploys scalp microelectrode streamlined in pointed end of arrangement so that scalp is micro-
Electrode avoids hair smoothly during dropping to scalp surface, electrode column head is blunt circle, permissible under the most certain pressure
Go deep into a scalp skin surface part but scalp skin will not be punctured, so can arrange scalp surface oil stain or dirt, with
Scalp surface is in close contact, and Graphene has good affinity because having outstanding electric conductivity simultaneously to tissue,
So there being the electrode column with Graphene coating can greatly strengthen the intensity of the collected signal of telecommunication and reduce in transmitting procedure
Loss.Stopping declining when electrode column head arrives at and gos deep into scalp skin rear electrode post, now electrode column trocar sheath continues to decline
Time with electrode column generation relative motion compression spring, the most flexible deployable electro-insulating rubber post by electrode column trocar sheath to
Under pressure and deform, because flexible deployable electro-insulating rubber vial wall is the most thinning by thickness from top to bottom, so from
Lower end thinnest part (flexible deployable electro-insulating rubber post outwards deforms expansion beginning portion) 1-12 starts deformation, and can open up along flexibility
Open electro-insulating rubber post to launch the channeling direction of guide portion 1-d and outwards against scalp surface and gradually extend deformation, from flexible deployable
Folding at electro-insulating rubber post folding part 1-11 and form double-layer circular plate-like, disk upper strata has coating for EMI shielding, disk lower floor to have soft
Property conducting film and scalp 1-13 be in close contact and be conductively connected with electrode column head, as it is shown on figure 3, scalp 1-13 ecto-entad depends on
Secondary for skin layer, hypodermis layer, galea aponeurotica layer.
As shown in Figures 5 to 7, full electromagnetic shielding short matrix self-aiming self-deploys scalp microelectrode array module, including micro-
Electrod-array module matrix part 2-1, the conducting terminal 2-3 that electrode wires collects plug 2-2, electrode wires collects in plug, scalp are micro-
Electrode 2-4 and microelectrode array module matrix part interconnector 2-5.
Microelectrode array module matrix part 2-1: in flat cube, is made up of insulation duroplasts, and one side has in array
The multiple cylindrical hole slot of arrangement, scalp microelectrode may be inserted into wherein, makes scalp microelectrode form short matrix array.This enforcement
The microelectrode array module matrix part that example is given is flat cube, it practice, microelectrode array module matrix part shape also may be used
Think other shape, such as circular, oval or given shape (as a certain cerebral cortex functional areas scalp maps shape), accordingly
The corresponding corresponding shape of electrode cap modular interface slot.
Electrode wires collects plug 2-2: connect corresponding scalp by microelectrode array module matrix part interconnector micro-
The electrode wires of electrode, after scalp microelectrode array module inserts electrode cap modular interface slot, connects with electrode cap modularity
Socket in mouth slot plugs.
Electrode wires collects the conducting terminal 2-3 in plug: is arranged on electrode wires and collects on plug.
Scalp microelectrode 2-4 is that the full electromagnetic shielding self-aiming shown in Fig. 2 to Fig. 4 self-deploys scalp microelectrode.
Microelectrode array module matrix part interconnector 2-5: every line one end connects the electrode that scalp microelectrode is drawn
Line, the other end connects electrode wires and collects the conducting terminal on plug, as shown in Figure 6.
Above-mentioned electrode wires collects plug 2-2 and microelectrode array module matrix part interconnector 2-5 and all uses electromagnetic shielding
Design.In module, microelectrode quantity and array arrangement mode can adjust according to specific requirement, collect number of terminals in plug conducting
Adjust also dependent on specific requirement.
As shown in Figure 8, modular interface full electromagnetic shielding bus transfer electrode cap includes electrode cap modular interface slot
3-1, electrode cap main body 3-2, ear hollow out forms 3-3, electrode cap frenulum 3-4, electrode cap frenulum fasten snap close 3-5, electrode cap
Bus cable 3-6.Multiple electrode cap modular interface slots are arranged in electrode cap body surfaces, and ear's hollow out forms are arranged on
The left and right sides of electrode cap main body lower end is so that pressing from both sides normal electrode in ear, and electrode cap is installed in the upper end of two arrays of electrodes cap frenulum
Main body lower end, the lower end of electrode cap frenulum and electrode cap frenulum tie-down snap close link together, and electrode cap bus cable is arranged on
Lower end on rear side of electrode cap main body.
Electrode cap modular interface slot self-deploys scalp microelectrode battle array for the full electromagnetic shielding of plug-in mounting short matrix self-aiming
Row module, it specifically installs relation as shown in FIG. 9 and 10.Electrode cap modular interface slot 3-1 is provided with electrode cap module
Changing the socket 3-7 in interface slot, microelectrode array module matrix part is inlaid in electrode cap modular interface slot, microelectrode
Electrode wires in array module collects plug and is installed together with the socket 3-7 in electrode cap modular interface slot, electrode cap
Socket extraction electrode cap interconnector 3-8 in modular interface slot also links together with electrode cap bus cable.Such as Fig. 9
Shown in, when microelectrode module being pressed in the direction of arrows in electrode cap modular interface slot, electrode wires collects plug and electrode
Socket in hat cone massing interface slot plugs, and such as Figure 10, and is aggregated into electrode cap bus electricity by electrode cap interconnector
In cable.
Socket in electrode cap modular interface slot, electrode cap interconnector, electrode cap bus cable all use electromagnetism
Shielding design.
Data bus interface signal amplifier: be connected with electrode cap bus cable, is used for receiving electrode cap bus cable
Signal and amplify, and will amplify after signal be sent to analog-digital converter.
Analog-digital converter: be connected with data bus interface signal amplifier, the mould transmitted for receiving signal amplifier
Intend signal and convert analog signals into the incoming computer of digital signal.
Whole human cortical brain's non-invasive detection of electroneurographic signal high sensitivity and the connection of analysis process system, such as Figure 11 institute
Show.
Signal data real-time analysis process system is installed, to computer to collected data by real time in computer
Automatically analyze, process.Owing to scalp microelectrode arranges closely, by multiple method obtain intensity more preferably, disturb and be lost
Less signal of telecommunication, such that it is able to Electrical Activities of Cerebral Cortex is carried out fine potentiometric analysis in the mapping of scalp surface, can be right
Some nervous system disease carries out finer analysis to the impact of brain, accomplishes early diagnosis, Precise Diagnosis, even to certain
A little nervous system disease have new understanding.Original data storage unit, real-time analysis and processing unit it is provided with in computer
(1) original data storage unit: countershaft records each scalp microelectrode and collects Scalp Potential data on time.
(2) analysis and processing unit realizes positioning analysis, qualitative analysis data base, action intent data storehouse and tradition in real time
Analyze, wherein:
Positioning analysis: as depicted in figs. 12 a and 12b, scalp corresponding to scalp microelectrode in a certain scalp microelectrode module
Coordinate, by analyzing in module each scalp microelectrode at potential data sometime, such as Figure 13, shown in 14, the micro-electricity of coordinate B2
Electrode potential is slightly below B2 (Lycoperdon polymorphum Vitt represents) apparently higher than other electrodes (black represents), coordinate A2, B1, B3, C2 microelectrode current potential,
Other coordinate microelectrode current potentials the lowest (white represent), we can see that coordinate B2 is focal electric discharge origin intuitively, along with
The passage of time, it to periphery spread, form an electric field, electric field gradually weakens.System can analyze all heads by countershaft on time
The potential change of each scalp microelectrode in skin microelectrode module, thus analysis part or the change of whole brain potential.
Qualitative analysis data base: the characteristic of more known nervous system disease is stored in qualitative analysis data base, is
Unite the initial data obtained and data automatic comparison in data base, thus automatically analyze out initial data and some nervous system
The matching degree of genius morbi data, thus assist medical worker to derive possible diagnosis.
Action intent data storehouse: storage normal population single action and the EEG signals characteristic of composite move, as lifted
Left forearm, close the composite moves such as the single actions such as right eye, walking.Immediately the original data signal obtained is intended to by system with action
Data base compares, and immediately derives people's intention now, and the enabling signal this being intended to is set to periphery by port output
Standby, such as assist, rehabilitation equipments etc. such as mechanical arm, machinery lower limb, make people's brain computer interfaces be possibly realized.
Traditional analysis: by initial data conversion be output as tradition lead more electroencephalogram waveform for research or user analysis make
With.
(3) output unit: analysis result can be exported to display device, printing device and can be exported to health by port
Multiple equipment, assist etc., it might even be possible to manipulation computer, as shown in figure 15.
The expanded function of signal data real-time analysis process system is installed in computer: this is that interior all software is the most permissible
Upgrading, all property data bases all can constantly be upgraded and share, can add more nervous system disease characteristic, to data
The variation of parsing software, meets the clinical and different requirements of scientific research, adds the availability of system, autgmentability and reduce maintenance
Cost.Some electroencephalogramsignal signal analyzing softwares that native system data are currently known by data point reuse compatibility, farthest meet
User or the use habit of researcher.Native system also can be miniaturized by single-chip microcomputer or computer, and whole system volume is permissible
The least even carrying with, creating for people's brain computer interfaces civil nature may.
It is emphasized that embodiment of the present invention is illustrative rather than determinate, bag the most of the present invention
Include the embodiment being not limited to described in detailed description of the invention, every by those skilled in the art according to technical scheme
Other embodiments drawn, also belong to the scope of protection of the invention.
Claims (10)
1. human cortical brain's non-invasive detection of electroneurographic signal high sensitivity and analysis process system, it is characterised in that: include
Full electromagnetic shielding bus transfer electrode cap, data bus interface signal amplifier, analog-digital converter and computer；Described full electromagnetism
Multiple full electromagnetic shieldings short matrix self-aiming is installed on mask bus transmission electrode cap and self-deploys scalp microelectrode array module,
Described full electromagnetic shielding short matrix self-aiming self-deploys scalp microelectrode array module and is bootstrapped by multiple full electromagnetic shielding self-aimings
Beginning skin microelectrode is constituted by certain matrix arrangement；Described full electromagnetic shielding short matrix self-aiming self-deploys scalp microelectrode array
Module gathers, in scalp surface detection, the signal of telecommunication that human cortical brain's electrical activity maps mutually in scalp surface, total by full electromagnetic shielding
Line transmission electrode cap transmits to data bus interface signal amplifier, data bus interface signal amplifier amplify and modulus turns
Being transferred to computer after changing, computer is analyzed processing by the internal real-time analysis process system of signal data.
Human cortical brain's non-invasive detection of electroneurographic signal high sensitivity the most according to claim 1 and analysis process system,
It is characterized in that: described full electromagnetic shielding bus transfer electrode cap include electrode cap modular interface slot, electrode cap main body and
Electrode cap bus cable, multiple electrode cap modular interface slots are arranged in electrode cap body surfaces, in electrode cap modularity
Full electromagnetic shielding short matrix self-aiming is installed in interface slot and self-deploys scalp microelectrode array module, described electrode cap bus electricity
One end of cable be connected with each electrode cap modular interface slot respectively, the other end of this electrode cap bus cable and data
Bus interface signals amplifier is connected.
Human cortical brain's non-invasive detection of electroneurographic signal high sensitivity the most according to claim 2 and analysis process system,
It is characterized in that: described electrode cap main body lower end is also equipped with Liang Ge ear hollow out forms, two arrays of electrodes cap frenulum, Liang Ge ear
Hollow out forms are arranged on the left and right sides of electrode cap main body lower end for pressing from both sides normal electrode in ear, two arrays of electrodes cap frenulum upper
End installs electrode cap main body lower end, and the lower end of electrode cap frenulum and electrode cap frenulum are fastened snap close and linked together.
Human cortical brain's non-invasive detection of electroneurographic signal high sensitivity the most according to claim 1 and analysis process system,
It is characterized in that: described full electromagnetic shielding short matrix self-aiming self-deploys scalp microelectrode array module and includes microelectrode array mould
Block matrix part, electrode wires collect plug, full electromagnetic shielding self-aiming self-deploys scalp microelectrode and microelectrode array module matrix
Portion's interconnector；Full electromagnetic shielding self-aiming self-deploys scalp microelectrode and is inlaid in microelectrode array module matrix part in array
In the multiple cylindrical hole slot of arrangement and collect plug by microelectrode array module matrix part interconnector with electrode wires to be connected
Connecing, described electrode wires collects plug and is arranged on the side of microelectrode array module matrix part, collects in electrode wires and is provided with on plug
Conducting terminal, this electrode wires collects plug for the electrode cap modular interface slot with full electromagnetic shielding bus transfer electrode cap
It is connected.
Human cortical brain's non-invasive detection of electroneurographic signal high sensitivity the most according to claim 4 and analysis process system,
It is characterized in that: described electrode wires collects plug and microelectrode array module matrix part interconnector all uses electromagnetic shielding to tie
Structure.
6. according to the human cortical brain's non-invasive detection of electroneurographic signal high sensitivity described in any one of claim 3 to 5 and analysis
Processing system, it is characterised in that: be provided with in electrode cap modular interface slot in described electrode cap modular interface slot inserts
Seat, microelectrode array module matrix part is inlaid in electrode cap modular interface slot, the electrode wires in microelectrode array module
Collect plug to be installed together with the socket in electrode cap modular interface slot, in each electrode cap modular interface slot
Socket extraction electrode cap interconnector collects composition electrode cap bus cable.
Human cortical brain's non-invasive detection of electroneurographic signal high sensitivity the most according to claim 6 and analysis process system,
It is characterized in that: the socket in described electrode cap modular interface slot, electrode cap interconnector, electrode cap bus cable are all adopted
Use electromagnetic armouring structure.
Human cortical brain's non-invasive detection of electroneurographic signal high sensitivity the most according to claim 1 and analysis process system,
It is characterized in that: described full electromagnetic shielding self-aiming self-deploys scalp microelectrode and includes electrode column, flexible deployable electro-insulating rubber
Post, cylindrical helical spring, electrode column trocar sheath, electrode wires, electro-insulating rubber pipe, deployable Graphene flexible conductive film and electromagnetism
Screen rubber；Described electrode column surface-coated has Graphene coating and is sleeved on electrode column trocar sheath and flexibility deployable insulation rubber
In glue post, the flexible upper end of deployable electro-insulating rubber post is connected fixing with the lower end of electrode column trocar sheath, this electro-insulating rubber post
Lower end is connected fixing with electrode column head；Described cylindrical helical spring is installed and is used for over the electrode shaft limiting electrode column trocar sheath
Range of movement；The bottom of described electrode wires is connected with the upper end of electrode column, is wrapped with insulating barrier and electromagnetism in electrode wires
Screen layer, electrode wires is fixed by being arranged on the electro-insulating rubber pipe of electrode column outer sleeve upper；Described deployable Graphene
Flexible conductive film covers the rear surface at flexible deployable electro-insulating rubber post, and is connected with electrode column head and mutually conducts electricity；
Stating the top parcel electrode column trocar sheath of electromagnetic shield rubber, flexible deployable electro-insulating rubber post top is wrapped up in bottom.
Human cortical brain's non-invasive detection of electroneurographic signal high sensitivity the most according to claim 1 and analysis process system,
It is characterized in that: described electrode column uses the good argent of electric conductivity as main material, and this electrode column head is blunt circle
Hemispherical, this electrode column main body is cylinder, electrode column main body is provided with stop retainer ring for limit electrode column relative to
The range of movement of electrode column trocar sheath also stops cylindrical helical spring.
Human cortical brain's non-invasive detection of electroneurographic signal high sensitivity the most according to claim 1 and analysis process system,
It is characterized in that: described electrode column trocar sheath is drum-shaped hard ambroin pipe, be provided with in electrode column trocar sheath annulus, in
Annulus and lower annulus, on this, annulus is used for fixed insulation rubber tube extraction electrode line, and in this, annulus is used for supporting electrode column cunning
Moving and limit spring, this lower annulus is used for supporting electrode column and slides and limit its downward range of motion.
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