CN106056173A - Biobank intelligent management system based on RFID and management method thereof - Google Patents
Biobank intelligent management system based on RFID and management method thereof Download PDFInfo
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- CN106056173A CN106056173A CN201610345891.3A CN201610345891A CN106056173A CN 106056173 A CN106056173 A CN 106056173A CN 201610345891 A CN201610345891 A CN 201610345891A CN 106056173 A CN106056173 A CN 106056173A
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- G—PHYSICS
- G06—COMPUTING; CALCULATING OR COUNTING
- G06K—GRAPHICAL DATA READING; PRESENTATION OF DATA; RECORD CARRIERS; HANDLING RECORD CARRIERS
- G06K17/00—Methods or arrangements for effecting co-operative working between equipments covered by two or more of main groups G06K1/00 - G06K15/00, e.g. automatic card files incorporating conveying and reading operations
- G06K17/0022—Methods or arrangements for effecting co-operative working between equipments covered by two or more of main groups G06K1/00 - G06K15/00, e.g. automatic card files incorporating conveying and reading operations arrangements or provisious for transferring data to distant stations, e.g. from a sensing device
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Abstract
Provided is a biobank intelligent management system based on RFID, comprising a technician terminal device, an RFID electronic label reader-writer, an electronic label printer, a server and an intelligent check and analysis system which are connected to form a local area network, and also comprising a plurality of RFID electronic label biological sample registers, wherein each RFID electronic label biological sample register bears an RFID electronic label, the RFID electronic label cooperates with the RFID electronic label reader-writer, and the intelligent check and analysis system compares different RFID electronic labels. The biobank intelligent management system can effectively perform intelligent digital management, and improve biobank identification and sample tracking.
Description
Technical field
The present invention relates to medicine technology field, a kind of biological sample bank intelligent management system based on RFID and
Management method.
Background technology
Biological sample bank, also known as biobank (Biobank), is primarily referred to as standardization and collects, processes, stores and apply strong
Health and the biomacromolecule of disease organism, cell, tissue and organ equal samples (include human organ tissue, whole blood, blood plasma,
Serum, biological fluid or processed biological specimen (DNA, RNA, albumen etc.) and face relevant to these biological specimens
Bed, pathology, treat, follow up a case by regular visits to, data and quality control, information management and the application system such as informed consent.
The manual type that overwhelming majority hospital or R&D institution use at present manages biological sample bank.Exist the most all
Many problems:
Storage box space availability ratio: after sample accumulation to some, manual mode is searched and to deposit sample extremely difficult
And easily make mistakes, container (such as refrigerator, the liquid nitrogen container) utilization ratio depositing sample also can be gradually lowered.Because sample at the beginning
Originally it is probably what classified order was deposited, but according to the difference of scientific research demand, sampling can take sample away from the diverse location of container,
After a period of time, container can produce substantial amounts of scattered room and but cannot effectively utilize.This is accomplished by utilizing information system
Carry out the distribution automatically of sample deposit position and search, improving the space efficiency utilization of the containers such as refrigerator.
The accuracy of sampling: this is directly connected to experimental result and research conclusion, the most out in the cold.We once listened
Said such example: a problem studying certain women's diseases, it is provided that a collection of clinical samples enters to commerce services mechanism
Row gene analysis, has been found that in experimentation that the patient that some of them sample is corresponding is male, and this allows for this this base of lot sample
Originally value is lost.Such problem is avoided to occur, can be by the most ripe low temperature bar coded sticker technology, scanning
Bar code carries out the verification of relevant information in software tool, just can effectively guarantee the accuracy of sampling.
The effectiveness followed up a case by regular visits to: patient resource is the most important strategic resource of hospital.Patient is carried out regular follow-up management, makes
Patient obtains lasting observation and reasonable successive treatment, services, preferably solve patient's slight illness before improving hospital doctor and after doctor
Hardship, and lasting, long-range doulbe-sides' victory relation is set up one by one with patient.Facilitate doctor that patient is followed the tracks of observation simultaneously, grasp first-hand
Data carries out statistical analysis, accumulates experience, beneficially research work carry out the raising with professional skill, be preferably clothes for patients
Business.
The management of supporting clinical data: the purpose collecting and preserving sample is for the needs according to clinical research, to disease
The sample of people screens, and obtains the expression such as the external symptom of patient and inherent gene, albumen by molecular biology experiment
Between association, if a sample lacks the most supporting clinical data, then that screens is based on insufficient grounds, and the scientific research value of sample is just
Have a greatly reduced quality.
The quality control of biological specimen: include sample collection subpackage, put in storage, sample, outbound whole during to sample matter
The monitoring of amount, it is to avoid the quality problems such as pollution, degraded occurs in sample.
Therefore, how to improve the security reliability of each biological sample bank experiment, realize the automatically record of data simultaneously so that
In inquiry in the future, analyze, add up, be the problem needing in prior art to solve.
Summary of the invention
It is an object of the invention to provide a kind of biological sample bank intelligent management system based on RFID and management method thereof,
Can effectively solve above-mentioned drawback.
The technical scheme is that
A kind of biological sample bank intelligent management system based on RFID, including technician terminal equipment, RFID
Read write line, electronic tag printer, server and intelligence verification and the system of analysis, described technician terminal equipment, RFID electronics
Tag read-write equipment, electronic tag printer, server and intelligence verification connect and compose LAN with analysis system, described based on
The biological sample bank intelligent management system of RFID also includes multiple radio frequency identification electronic label biological specimen receptacle, each
Described radio frequency identification electronic label biological specimen receptacle carrying RFID, described RFID is with described
RFID read write line coordinates, intelligence verification compare different RFID from analysis system.
Described technician terminal equipment is smart mobile phone or panel computer.
A kind of biological sample bank intelligent management based on RFID, is characterized in that comprising the following steps:
1) technician terminal equipment is according to logon information record operator；
2) technician uses the technician terminal equipment record organization sample collection date；
3) technician uses the technician terminal equipment record major arteries blood supply detachment time, and when specimens from pri is in vitro
Between；
4) technician uses technician terminal equipment record clinical research key；
5) technician uses technician terminal equipment to take pictures, and records sample general pathology situation；
6) technician uses radio frequency identification electronic label biological specimen receptacle to extract biological specimen；
7) technician uses technician terminal equipment record cryopreserved tissue sample to insert the liquid nitrogen time, and paraffin embedding group
Knit sample and insert the formalin time；
8) technician terminal equipment automatic decision tissue samples is from vitro to inserting liquid nitrogen or formalin time less than setting
Fixed minute, and record；
9) sample is sent back to biological sample bank by technician, and puts in storage, penetrates by the scanning of RFID read write line is wireless
Frequency identifies that electronic tag biological specimen receptacle obtains storage location, is shown in screen, and specifying information is as follows, and technician terminal sets
The date and time into liquid nitrogen container deposited by memorandum；
10) technician terminal equipment record centrifugal condition, centrifugation time, centrifuge model；
11, the supernatant obtained after being centrifuged is transferred in the yellow lid cryopreservation tube that numbering is corresponding, at technician terminal equipment
On fill in.
Described technician terminal equipment is smart mobile phone or panel computer.
The invention has the beneficial effects as follows:
The biological sample bank intelligent management system based on RFID of the present invention and management method thereof can effectively be carried out can only
Digital management, the identification of perfect biological sample bank and follow the trail of sample:
A) sample after extraction, subpackage should be able to be traced back to original sample by information system and be associated with its information；
B) every part of sample should have and only only one or a group identifier number (numeral or bar shaped in information system
Code)；
C) sample from collect process, store, transport of providing and delivering, use after residue return the overall process of storage again etc. and all answer
By effective record；
D) transfer of biological specimen should be by timely record, and information system can trace back to the change of each sample storage location
More.
The biological sample bank intelligent management system based on RFID of the present invention and management method thereof solve biological sample bank
Gathering the security concern during preserving, system is numbered for different biological specimen distribution sole electron, each link
Processing the correctness all being checked biological specimen by computer according to uniqueness, any error system all can pass through voice and image
Automatic alarm, system can control strict to experiment flow, it is to avoid misses operation link.
Stop the error that laboratory anthropic factor occurs.Management for laboratory provides data to support all of operation data
Automatically record, persistence, can review, can retrieve, can automatically analyze out form.Improved flow for laboratory is got positive
Promote meaning.
Achieve the science digital management of experiment flow, make operation more transparent, testimony of a witness association and the electronization of verification
Display, cross-check information doctors and patients visualize shared, and data can forever retain in case checking, and eliminate patient's doubt, strengthen the letter of doctors and patients
Appoint.Improving laboratory work efficient, the design of system has taken into full account the custom that existing lab assistant operate, device therefor with
Flow scheme design has been passed through on-the-spot test many times and has been improved, and greatly reduces original manual processing links, accelerates process
Speed, accomplishes fully to discharge the operating pressure of people, improves work efficiency.
Accompanying drawing explanation
Fig. 1 is the system structure schematic diagram of the present invention.
Detailed description of the invention
The invention will be further described below in conjunction with the accompanying drawings:
Such as Fig. 1, a kind of biological sample bank intelligent management system based on RFID, including technician terminal equipment, RFID electricity
Subtab read write line, electronic tag printer, server and intelligence verification and the system of analysis, described technician terminal equipment,
RFID read write line, electronic tag printer, server and intelligence verification connect and compose LAN with analysis system,
Described biological sample bank intelligent management system based on RFID also includes that multiple radio frequency identification electronic label biological specimen is deposited
Put device, each described radio frequency identification electronic label biological specimen receptacle carrying RFID, described RFID electronics
Label coordinates with described RFID read write line, intelligence verification carry out different RFID from analysis system
Comparison.
Described technician terminal equipment is smart mobile phone or panel computer.
A kind of biological sample bank intelligent management based on RFID, is characterized in that comprising the following steps:
1) technician terminal equipment is according to logon information record operator；
2) technician uses the technician terminal equipment record organization sample collection date；
3) technician uses the technician terminal equipment record major arteries blood supply detachment time, and when specimens from pri is in vitro
Between；
4) technician uses technician terminal equipment record clinical research key；
5) technician uses technician terminal equipment to take pictures, and records sample general pathology situation；
6) technician uses radio frequency identification electronic label biological specimen receptacle to extract biological specimen；
7) technician uses technician terminal equipment record cryopreserved tissue sample to insert the liquid nitrogen time, and paraffin embedding group
Knit sample and insert the formalin time；
8) technician terminal equipment automatic decision tissue samples is from vitro to inserting liquid nitrogen or formalin time less than setting
Fixed minute, and record；
9) sample is sent back to biological sample bank by technician, and puts in storage, penetrates by the scanning of RFID read write line is wireless
Frequency identifies that electronic tag biological specimen receptacle obtains storage location, is shown in screen, and specifying information is as follows, and technician terminal sets
The date and time into liquid nitrogen container deposited by memorandum；
10) technician terminal equipment record centrifugal condition, centrifugation time, centrifuge model；
11, the supernatant obtained after being centrifuged is transferred in the yellow lid cryopreservation tube that numbering is corresponding, at technician terminal equipment
On fill in.
Described technician terminal equipment is smart mobile phone or panel computer.
It is CT500's that RFID read write line can be selected for the model of Shanghai Chu Teng Information Technology Co., Ltd production
RFID read write line.
Server can be selected for the R720 server of Dell.Electronic tag printer can be selected for Toshiba SX5 model printer.
Intelligence verification can be selected for, with analysis system, the product that Shanghai Chu Teng Information Technology Co., Ltd produces.
Embodiment one, blood sample collect flow process
1, technician terminal equipment is according to logon information record operator (Clinical Researcher)；
2, Clinical Researcher signs Informed Consent Form, uses technician terminal equipment to take Informed Consent Form, simultaneously in skill
Informed Consent Form version number (drop-down menu) is recorded on art person's terminal unit；
3, nurse's blood drawing, Clinical Researcher uses technician terminal equipment record: the blood drawing date, the blood drawing time, bleeder,
Bleeder job number；
4, EDTA-K2 anticoagulant tube (purple lid) soft dematron 10 times, technician terminal equipment record (single choice)；5, clinical research
Blood sample is delivered to biological sample bank by member, uses technician terminal equipment record delivery time；
6, technician terminal equipment automatic decision from blood drawing to whether sending to biological sample bank more than 40 minutes, and record.
Embodiment two, solid tumor tissue sample collection flow process
1, technician terminal equipment is according to logon information record operator (technician)；
2, technician uses the technician terminal equipment record organization sample collection date；
3, technician uses the technician terminal equipment record major arteries blood supply detachment time, and when specimens from pri is in vitro
Between；
4, technician uses technician terminal equipment record clinical research key；
5, technician uses technician terminal equipment to take pictures, and records sample general pathology situation；
6, technician is according to SOP requirement, carries out tissue samples and draws materials；
7, technician uses technician terminal equipment record cryopreserved tissue sample to insert the liquid nitrogen time, and paraffin embedding group
Knit sample and insert the formalin time；
8, technician terminal equipment automatic decision tissue samples is from vitro to inserting liquid nitrogen or formalin time less than 20
Minute, and record；
9, sample is sent back to biological sample bank by technician, and puts in storage (from biological sample bank software acquisition storage location, display
In screen, specifying information is as follows), the date and time into liquid nitrogen container deposited in technician terminal equipment record；
Liquid nitrogen container number: shelf number: box number:
| FT-1 | FT-2 | FT-3 | FN-1 | FN-2 | FN-3 |
10, technician uses technician terminal equipment record special circumstances.
Embodiment three, cystic tumor sample collection flow process
1, technician terminal equipment is according to logon information record operator (technician)；
2, technician uses the technician terminal equipment record organization sample collection date；
3, technician uses the technician terminal equipment record major arteries blood supply detachment time, and when specimens from pri is in vitro
Between；
4, technician uses technician terminal equipment record clinical research key；
5, technician uses technician terminal equipment to take pictures, and records sample general pathology situation；
6, increase takes capsule liquid specimen, and technician uses 3 EP pipes respectively to take 1mL capsule liquid；
7, technician uses technician terminal equipment record cryopreserved tissue sample to insert the liquid nitrogen time, and paraffin embedding group
Knit sample and insert the formalin time；
8, technician terminal equipment automatic decision tissue samples is from vitro to inserting liquid nitrogen or formalin time less than 20
Minute, and record；
9, sample is sent back to biological sample bank by technician, and puts in storage (from biological sample bank software acquisition storage location, display
In screen, specifying information is as follows), the date and time into liquid nitrogen container deposited in technician terminal equipment record；
Liquid nitrogen container number: shelf number: box number:
| FT-1 | FT-2 | FT-3 | FN-1 | FN-2 | FN-3 |
10, technician adds 100uL DPBS in equipped with the 1.5mL EP pipe of capsule liquid, uses technician terminal equipment note
Record (single choice)；
11, centrifugal, technician terminal equipment record centrifugal condition (drop-down menu), centrifugation time (drop-down menu), centrifugal
Type number (drop-down menu)；
12, supernatant is transferred in the yellow lid cryopreservation tube that numbering is corresponding, technician terminal equipment is filled in and (reaches
The direct of SOP requirement beats √ in space, please fill in about volume such as what volume was not up to, and the non-subpackage of volume deficiency is then in space
In beat ×):
13, by capsule liquid sample warehouse-in, (obtaining storage location from biological sample bank software, be shown in screen, specifying information is such as
Under), the date and time into refrigerator deposited in technician terminal equipment record；
Refrigerator number: grid number: shelf number: box number:
14, technician uses technician terminal equipment record special circumstances.
Embodiment four, serum sample separation process (possible multiple clinical samples operate simultaneously)
1, technician terminal equipment is according to logon information record operator (technician)；
2, technician's subpackage blood plasma, according to subpackage situation, fills on technician terminal equipment and (reaches the straight of SOP requirement
Beat √ in being connected on space, as volume not up to please fill in about volume, the non-subpackage of volume deficiency then beats in space ×):
| (μL) | 1 | 2 | 3 | 4 | 5 | 6 |
| Blood plasma | ||||||
| Hemocyte |
3, technician is centrifuged, technician terminal equipment record centrifugal condition (drop-down menu), centrifugation time (drop-down menu),
Centrifuge model (drop-down menu)；
4, by blood sample warehouse-in, (obtaining storage location from biological sample bank software, be shown in screen, specifying information is such as
Under), the date and time into refrigerator deposited in technician terminal equipment record；
Refrigerator number: grid number: shelf number: box number:
| 1 | 2 | 3 | 4 | 5 | 6 | |
| Blood plasma | ||||||
| Hemocyte |
5, technician terminal equipment automatic decision from blood drawing to whether inserting refrigerator more than 2 hours, and record；
6, technician uses technician terminal equipment record special circumstances.
Embodiment five, serum sample separation process (possible multiple clinical samples operate simultaneously)
1, technician terminal equipment is according to logon information record operator (technician)；
2, technician confirms that serum sample has stood 30 minutes before centrifugal, fills in (single on technician terminal equipment
Choosing)；
3, technician is centrifuged, technician terminal equipment record centrifugal condition (drop-down menu), centrifugation time (drop-down menu),
Centrifuge model (drop-down menu)；
4, technician's subpackage serum, according to subpackage situation, fills on technician terminal equipment and (reaches the straight of SOP requirement
Beat √ in being connected on space, as volume not up to please fill in about volume, the non-subpackage of volume deficiency then beats in space ×):
5, by blood sample warehouse-in, (obtaining storage location from biological sample bank software, be shown in screen, specifying information is such as
Under), the date and time into refrigerator deposited in technician terminal equipment record；
Refrigerator number: grid number: shelf number: box number:
| 1 | 2 | 3 | 4 | |
| Serum |
6, technician terminal equipment automatic decision from blood drawing to whether inserting refrigerator more than 2 hours, and record；
7, technician uses technician terminal equipment record special circumstances.
Embodiment described above is only to be described the preferred embodiment of the present invention, the not structure to the present invention
Thinking and scope is defined, without departing under design concept premise of the present invention, in this area, ordinary skill technical staff is to this
Various modification that bright technical scheme is made and improvement, all should fall into protection scope of the present invention, the skill that the present invention is claimed
Art content is the most all recorded in detail in the claims.
Claims (4)
1. a biological sample bank intelligent management system based on RFID, is characterized in that including technician terminal equipment, RFID electricity
Subtab read write line, electronic tag printer, server and intelligence verification and the system of analysis, described technician terminal equipment,
RFID read write line, electronic tag printer, server and intelligence verification connect and compose LAN with analysis system,
Described biological sample bank intelligent management system based on RFID also includes that multiple radio frequency identification electronic label biological specimen is deposited
Put device, each described radio frequency identification electronic label biological specimen receptacle carrying RFID, described RFID electronics
Label coordinates with described RFID read write line, intelligence verification carry out different RFID from analysis system
Comparison.
Biological sample bank intelligent management system based on RFID the most according to claim 1, it is characterised in that described technology
Member's terminal unit is smart mobile phone or panel computer.
3. a biological sample bank intelligent management based on RFID, is characterized in that comprising the following steps:
1) technician terminal equipment is according to logon information record operator；
2) technician uses the technician terminal equipment record organization sample collection date；
3) technician uses technician terminal equipment record major arteries blood supply detachment time, and specimens from pri isolated time；
4) technician uses technician terminal equipment record clinical research key；
5) technician uses technician terminal equipment to take pictures, and records sample general pathology situation；
6) technician uses radio frequency identification electronic label biological specimen receptacle to extract biological specimen；
7) technician uses technician terminal equipment record cryopreserved tissue sample to insert the liquid nitrogen time, and paraffin-embedded tissue sample
Originally the formalin time is inserted；
8) technician terminal equipment automatic decision tissue samples is from vitro to inserting liquid nitrogen or formalin time less than setting point
Clock, and record；
9) sample is sent back to biological sample bank by technician, and puts in storage, is known by RFID read write line scanning less radio-frequency
Other electronic tag biological specimen receptacle obtains storage location, is shown in screen, and specifying information is as follows, and technician terminal equipment is remembered
Record the date and time putting into liquid nitrogen container；
10) technician terminal equipment record centrifugal condition, centrifugation time, centrifuge model；
11, the supernatant obtained after being centrifuged is transferred in the yellow lid cryopreservation tube that numbering is corresponding, fills out on technician terminal equipment
Write.
Biological sample bank intelligent management based on RFID the most according to claim 1, it is characterised in that described technology
Member's terminal unit is smart mobile phone or panel computer.
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|---|---|---|---|
| CN201610345891.3A CN106056173A (en) | 2016-05-23 | 2016-05-23 | Biobank intelligent management system based on RFID and management method thereof |
Applications Claiming Priority (1)
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|---|---|---|---|
| CN201610345891.3A CN106056173A (en) | 2016-05-23 | 2016-05-23 | Biobank intelligent management system based on RFID and management method thereof |
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Cited By (8)
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|---|---|---|---|---|
| CN106372818A (en) * | 2016-11-04 | 2017-02-01 | 成都青软青之软件有限公司 | Laboratory sample flow management system |
| CN108564145A (en) * | 2017-12-29 | 2018-09-21 | 北京康瑞德医疗器械有限公司 | Operating room Pathologic specimen management information system |
| CN110143390A (en) * | 2019-06-05 | 2019-08-20 | 深圳市维思安科技发展有限公司 | Blood product access arrangement, blood product access method |
| CN111783913A (en) * | 2020-06-29 | 2020-10-16 | 重庆市柏玮熠科技有限公司 | IVF sample freezing positioning system |
| CN113057160A (en) * | 2020-01-02 | 2021-07-02 | 钟影 | Biological sample freezing management processing method and system |
| CN117132061A (en) * | 2023-08-28 | 2023-11-28 | 阿坝藏族羌族自治州食品药品检验研究中心 | System and method for managing traditional Chinese medicine specimen data based on wireless radio frequency |
| CN117236839A (en) * | 2022-09-21 | 2023-12-15 | 昭衍(北京)检测技术有限公司 | Sample management method and system |
| CN117556841A (en) * | 2024-01-11 | 2024-02-13 | 力盟生命科技(深圳)有限公司 | Biological sample checking and tracing system and method |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN106372818A (en) * | 2016-11-04 | 2017-02-01 | 成都青软青之软件有限公司 | Laboratory sample flow management system |
| CN108564145A (en) * | 2017-12-29 | 2018-09-21 | 北京康瑞德医疗器械有限公司 | Operating room Pathologic specimen management information system |
| CN110143390A (en) * | 2019-06-05 | 2019-08-20 | 深圳市维思安科技发展有限公司 | Blood product access arrangement, blood product access method |
| CN113057160A (en) * | 2020-01-02 | 2021-07-02 | 钟影 | Biological sample freezing management processing method and system |
| CN111783913A (en) * | 2020-06-29 | 2020-10-16 | 重庆市柏玮熠科技有限公司 | IVF sample freezing positioning system |
| CN117236839A (en) * | 2022-09-21 | 2023-12-15 | 昭衍(北京)检测技术有限公司 | Sample management method and system |
| CN117132061A (en) * | 2023-08-28 | 2023-11-28 | 阿坝藏族羌族自治州食品药品检验研究中心 | System and method for managing traditional Chinese medicine specimen data based on wireless radio frequency |
| CN117132061B (en) * | 2023-08-28 | 2024-03-08 | 阿坝藏族羌族自治州食品药品检验研究中心 | System and method for managing traditional Chinese medicine specimen data based on wireless radio frequency |
| CN117556841A (en) * | 2024-01-11 | 2024-02-13 | 力盟生命科技(深圳)有限公司 | Biological sample checking and tracing system and method |
| CN117556841B (en) * | 2024-01-11 | 2024-05-07 | 力盟生命科技(深圳)有限公司 | Biological sample checking and tracing system and method |
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