CN106042552A - Moisture absorption type high-barrier blister packaging rigid sheet - Google Patents
Moisture absorption type high-barrier blister packaging rigid sheet Download PDFInfo
- Publication number
- CN106042552A CN106042552A CN201610408584.5A CN201610408584A CN106042552A CN 106042552 A CN106042552 A CN 106042552A CN 201610408584 A CN201610408584 A CN 201610408584A CN 106042552 A CN106042552 A CN 106042552A
- Authority
- CN
- China
- Prior art keywords
- moisture absorption
- type high
- absorption type
- barrier
- blister package
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
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Classifications
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- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/06—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material
- B32B27/08—Layered products comprising a layer of synthetic resin as the main or only constituent of a layer, which is next to another layer of the same or of a different material of synthetic resin
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/18—Layered products comprising a layer of synthetic resin characterised by the use of special additives
- B32B27/20—Layered products comprising a layer of synthetic resin characterised by the use of special additives using fillers, pigments, thixotroping agents
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/30—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers
- B32B27/304—Layered products comprising a layer of synthetic resin comprising vinyl (co)polymers; comprising acrylic (co)polymers comprising vinyl halide (co)polymers, e.g. PVC, PVDC, PVF, PVDF
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B27/00—Layered products comprising a layer of synthetic resin
- B32B27/32—Layered products comprising a layer of synthetic resin comprising polyolefins
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B7/00—Layered products characterised by the relation between layers; Layered products characterised by the relative orientation of features between layers, or by the relative values of a measurable parameter between layers, i.e. products comprising layers having different physical, chemical or physicochemical properties; Layered products characterised by the interconnection of layers
- B32B7/04—Interconnection of layers
- B32B7/12—Interconnection of layers using interposed adhesives or interposed materials with bonding properties
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2307/00—Properties of the layers or laminate
- B32B2307/70—Other properties
- B32B2307/728—Hydrophilic
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B32—LAYERED PRODUCTS
- B32B—LAYERED PRODUCTS, i.e. PRODUCTS BUILT-UP OF STRATA OF FLAT OR NON-FLAT, e.g. CELLULAR OR HONEYCOMB, FORM
- B32B2439/00—Containers; Receptacles
- B32B2439/80—Medical packaging
Landscapes
- Laminated Bodies (AREA)
- Packages (AREA)
Abstract
The invention relates to a moisture absorption type high-barrier blister packaging rigid sheet. The moisture absorption type high-barrier blister packaging rigid sheet comprises a polytrifluorochloroethylene layer, a first polyurethane adhesive layer, a polyvinyl chloride layer, a second polyurethane adhesive and a moisture absorption film layer. By combination of high-barrier materials and moisture absorption functional materials, permeation of vapor on the front surface of packaging materials towards inner package space can be reduced while moisture permeating towards the inner package space from edges of heat seal portions of the packaging materials can be effectively and fixedly adsorbed, and moisture in air sealed in packages can be adsorbed and reduced, so that a quality protection function of medicine blister packages can be improved.
Description
Technical field
The present invention relates to drug packing material field, particularly to a kind of moisture absorption type high-barrier blister package stiff sheet.
Background technology
China medical bubble-cap packaged form development in recent years speed quickly, to simple in construction, quick heat sealing equipment
Demand increases day by day, and occurs in that multiple choices, and the product for many little and difficult packagings provides effective solution.At medicine
Product blister packaging materials aspect, the past, China relied primarily on import, and up till now, blister package aluminium foil and blister material are the most complete
Portion domesticizes, and can meet the demand of domestic drug packaging；The development of domestic one-tenth bubble base material gradually forms seriation, from the most extensive
The PVC stiff sheet used, to composites such as PVDC coated sheet and the plastic-aluminum combined sheet materials of cold forming.
Medicine is very sensitive to humidity, so as base material used in medicine blister package, it is desirable to bubble-cap material
Material can protect medicine effectively, and therefore the packaging material of high-barrier are applied in high-grade blister package.And according to medicine
These design of materials to water vapor sensitive in various degree, are become the product line of different barrier property, to obtain barrier property by product
Optimal collocation with packing cost.
Polytrifluorochloroethylene stiff sheet material has good vapor water barriers performance, but for the medicine of some special pearls requirements
Product packaging still suffers from technical deficiency.In know-why, it can only reduce packaging material front steam to package interior
The infiltration in space, and this barrier is the best, and corresponding packaging material cost is the highest.Simple packaging material of pursuing intercept
Property, it is impossible to effectively solve external water steam to packaging material from edge, heat-sealing portion to the infiltration in package interior space, can not subtract
Moisture in air in moisture part of few drug substance surface absorption when packaging operation and inclosure packaging.Typical a kind of packaging is then
The blister package of effervescent tablet, the gas phenomenon that rises as can not be effectively removed moisture during packaging operation, then after causing packaging.
And if blister packaging materials used self has the effect of the fixing moisture of absorption, then can fix from bag by active adsorption
Edge, package material heat-sealing portion, to the infiltration moisture in package interior space, also can adsorb and reduce the moisture enclosed in the interior air of packaging,
Thus improve the function of guaranteeing the quality of medicine blister package.
Summary of the invention
The deficiency existed for prior art, this case provides a kind of moisture absorption type high-barrier blister package stiff sheet, due to bubble
Cover packaging inner layer material has an effect of the fixing moisture of absorption, therefore can active adsorption fixing from edge, packaging material heat-sealing portion to
The infiltration moisture in package interior space, also can adsorb and reduce the moisture enclosed in the interior air of packaging, thus improve medicine blister pack
The function of guaranteeing the quality of dress.
For achieving the above object, this case is achieved through the following technical solutions:
A kind of moisture absorption type high-barrier blister package stiff sheet, it is sequentially provided with under upper: polytrifluorochloroethylene layer, first gather
Urethane adhesive layer, polyvinyl chloride layer, the second adhesive for polyurethane layer and hygroscopic film layer.
Preferably, described moisture absorption type high-barrier blister package stiff sheet, wherein, the thickness of described polytrifluorochloroethylene layer
For 15-102 μm.
Preferably, described moisture absorption type high-barrier blister package stiff sheet, wherein, the thickness of described polyvinyl chloride layer is
60-200μm。
Preferably, described moisture absorption type high-barrier blister package stiff sheet, wherein, the thickness of described hygroscopic film layer is
50-100μm。
Preferably, described moisture absorption type high-barrier blister package stiff sheet, wherein, described hygroscopic film layer include poly-
Ethylene and modifying agent.
Preferably, described moisture absorption type high-barrier blister package stiff sheet, wherein, described modifying agent includes:
Cyclic olefine copolymer 40-50wt%；
Kieselguhr 5-10wt%；
Zeolite crystal 40-55wt%；
Above-mentioned each component sum is 100wt%.
Preferably, described moisture absorption type high-barrier blister package stiff sheet, wherein, in parts by weight, described polyethylene: institute
State modifying agent=100: 10-18.
Preferably, described moisture absorption type high-barrier blister package stiff sheet, wherein, the particle diameter of described zeolite crystal is 2-5 μ
m。
The invention has the beneficial effects as follows: high barrier material is combined with moisture absorbing material by this case, can reduce
The infiltration to package interior space of the packaging material front steam, moreover it is possible to active adsorption fixing from edge, packaging material heat-sealing portion to
The infiltration moisture in package interior space, also can adsorb and reduce the moisture enclosed in the interior air of packaging, thus improve medicine blister pack
The function of guaranteeing the quality of dress.
Accompanying drawing explanation
Fig. 1 is the structural representation of moisture absorption type high-barrier blister package stiff sheet.
Detailed description of the invention
The present invention is described in further detail below in conjunction with the accompanying drawings, to make those skilled in the art with reference to description literary composition
Word can be implemented according to this.
As it is shown in figure 1, the moisture absorption type high-barrier blister package stiff sheet of an embodiment is listed in this case, it sets under upper successively
Have: polytrifluorochloroethylene layer the 1, first adhesive for polyurethane layer 2, polyvinyl chloride layer the 3, second adhesive for polyurethane layer 4 and moisture absorption
Thin layer 5.
Wherein, the thickness of polytrifluorochloroethylene layer 1 is preferably 15-102 μm.
Wherein, the thickness of polyvinyl chloride layer 3 is preferably 60-200 μm.
Wherein, the thickness of hygroscopic film layer 5 is preferably 50-100 μm.
Wherein, hygroscopic film layer 5 includes polyethylene and modifying agent.
As another embodiment of this case, wherein, modifying agent includes:
Cyclic olefine copolymer 40-50wt%；
Kieselguhr 5-10wt%；
Zeolite crystal 40-55wt%；
Above-mentioned each component sum is 100wt%.
In modifying agent, three kinds of compositions as an inseparable organic whole, the common moisture absorption improving polyethylene and
Guarantee the quality function.Wherein, cyclic olefine copolymer is mainly used in improving the lock aqueous energy of polyethylene so that hydrone at high temperature will not
To bubble-cap Inner extrusion；Kieselguhr is mainly used in solving zeolite crystal and the mixed consistency problem of polyethylene, with overcome because of
The introducing of zeolite crystal and cause the toughness of polyethylene to be affected, meanwhile, cyclic olefine copolymer can also improve polyethylene with
The adhesive for polyurethane bond strength when being heat-sealed and stability；Kieselguhr can reduce zeolite crystal at different temperatures
The difference of the coefficient of expansion so that the sensitivity of temperature is slowed up by zeolite crystal, so that zeolite crystal is to hydrone
Sweeping along ability not to be influenced by temperature, the moisture pick-up properties making packaging material is more stable.
Wherein, the proportioning of polyethylene and modifying agent has a preferred scope, in parts by weight, polyethylene: modifying agent=
100∶10-18.If beyond this scope, the moisture pick-up properties causing blister packaging materials being affected.
Wherein, the particle diameter of zeolite crystal is preferably 2-5 μm.
Research finds, in zeolite crystal, the outward appearance of moisture pick-up properties and final products is had necessarily by the size of zeolite
Impact, the particle diameter of zeolite is preferably controlled within the scope of 2-5 μm.
Except including polyethylene and modifying agent in hygroscopic film layer, may preferably further comprise the surfactant of routine,
These surfactants need to be only that polyethylene field is conventional, and this case no longer limits at this.
The moist steam absorbance of the moisture absorption type high-barrier blister package stiff sheet of this case (MVTR/38 DEG C, 90%RH (g/ (m2·
24h)) ＜ 0.1, barrier rank is fabulous；Its internal hydroscopicity ＞ 0.05%/1d.
Although embodiment of the present invention are disclosed as above, but it is not restricted in description and embodiment listed
Using, it can be applied to various applicable the field of the invention completely, for those skilled in the art, and can be easily
Realizing other amendment, therefore under the general concept limited without departing substantially from claim and equivalency range, the present invention does not limit
In specific details with shown here as the legend with description.
Claims (8)
1. a moisture absorption type high-barrier blister package stiff sheet, it is characterised in that be sequentially provided with under upper: polytrifluorochloroethylene
Layer, the first adhesive for polyurethane layer, polyvinyl chloride layer, the second adhesive for polyurethane layer and hygroscopic film layer.
2. moisture absorption type high-barrier blister package stiff sheet as claimed in claim 1, it is characterised in that described polytrifluorochloroethylene layer
Thickness be 15-102 μm.
3. moisture absorption type high-barrier blister package stiff sheet as claimed in claim 1, it is characterised in that the thickness of described polyvinyl chloride layer
Degree is 60-200 μm.
4. moisture absorption type high-barrier blister package stiff sheet as claimed in claim 1, it is characterised in that the thickness of described hygroscopic film layer
Degree is 50-100 μm.
5. moisture absorption type high-barrier blister package stiff sheet as claimed in claim 1, it is characterised in that wrap in described hygroscopic film layer
Polyethylene and modifying agent are included.
6. moisture absorption type high-barrier blister package stiff sheet as claimed in claim 5, it is characterised in that described modifying agent includes:
Cyclic olefine copolymer 40-50wt%；
Kieselguhr 5-10wt%；
Zeolite crystal 40-55wt%；
Above-mentioned each component sum is 100wt%.
7. moisture absorption type high-barrier blister package stiff sheet as claimed in claim 6, it is characterised in that in parts by weight, described poly-
Ethylene: described modifying agent=100: 10-18.
8. moisture absorption type high-barrier blister package stiff sheet as claimed in claim 6, it is characterised in that the particle diameter of described zeolite crystal
For 2-5 μm.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610408584.5A CN106042552B (en) | 2016-06-12 | 2016-06-12 | Moisture absorption type high-barrier blister package stiff sheet |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610408584.5A CN106042552B (en) | 2016-06-12 | 2016-06-12 | Moisture absorption type high-barrier blister package stiff sheet |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| CN106042552A true CN106042552A (en) | 2016-10-26 |
| CN106042552B CN106042552B (en) | 2018-06-26 |
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Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| CN201610408584.5A Active CN106042552B (en) | 2016-06-12 | 2016-06-12 | Moisture absorption type high-barrier blister package stiff sheet |
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Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US20110266189A1 (en) * | 2010-05-03 | 2011-11-03 | Tom Nicole L | Blister packaging |
| CN102438825A (en) * | 2009-03-20 | 2012-05-02 | 阿姆科挠性物品克罗伊茨林根有限公司 | Cover foil designed as push-through foil for a blister package |
| CN102615892A (en) * | 2011-01-27 | 2012-08-01 | 苏州海顺包装材料有限公司 | Medicinal full-insulation transparent composite hard sheet |
| CN205674634U (en) * | 2016-06-12 | 2016-11-09 | 苏州海顺包装材料有限公司 | Moisture absorption type high-barrier blister package stiff sheet |
-
2016
- 2016-06-12 CN CN201610408584.5A patent/CN106042552B/en active Active
Patent Citations (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN102438825A (en) * | 2009-03-20 | 2012-05-02 | 阿姆科挠性物品克罗伊茨林根有限公司 | Cover foil designed as push-through foil for a blister package |
| US20110266189A1 (en) * | 2010-05-03 | 2011-11-03 | Tom Nicole L | Blister packaging |
| CN102615892A (en) * | 2011-01-27 | 2012-08-01 | 苏州海顺包装材料有限公司 | Medicinal full-insulation transparent composite hard sheet |
| CN205674634U (en) * | 2016-06-12 | 2016-11-09 | 苏州海顺包装材料有限公司 | Moisture absorption type high-barrier blister package stiff sheet |
Also Published As
| Publication number | Publication date |
|---|---|
| CN106042552B (en) | 2018-06-26 |
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