CN106038872A - Composition with function of alleviating asthenopia - Google Patents

Composition with function of alleviating asthenopia Download PDF

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Publication number
CN106038872A
CN106038872A CN201610467974.XA CN201610467974A CN106038872A CN 106038872 A CN106038872 A CN 106038872A CN 201610467974 A CN201610467974 A CN 201610467974A CN 106038872 A CN106038872 A CN 106038872A
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extract
weight portion
weight
aloe
citri tangerinae
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何云
汪长国
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HUBEI LISHENGTANG BIOTECHNOLOGY CO Ltd
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HUBEI LISHENGTANG BIOTECHNOLOGY CO Ltd
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/886Aloeaceae (Aloe family), e.g. aloe vera
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/28Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/45Ericaceae or Vacciniaceae (Heath or Blueberry family), e.g. blueberry, cranberry or bilberry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/48Fabaceae or Leguminosae (Pea or Legume family); Caesalpiniaceae; Mimosaceae; Papilionaceae
    • A61K36/482Cassia, e.g. golden shower tree
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/73Rosaceae (Rose family), e.g. strawberry, chokeberry, blackberry, pear or firethorn
    • A61K36/738Rosa (rose)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/81Solanaceae (Potato family), e.g. tobacco, nightshade, tomato, belladonna, capsicum or jimsonweed
    • A61K36/815Lycium (desert-thorn)
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/896Liliaceae (Lily family), e.g. daylily, plantain lily, Hyacinth or narcissus
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/30Macromolecular organic or inorganic compounds, e.g. inorganic polyphosphates
    • A61K47/36Polysaccharides; Derivatives thereof, e.g. gums, starch, alginate, dextrin, hyaluronic acid, chitosan, inulin, agar or pectin
    • A61K47/38Cellulose; Derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/30Extraction of the material
    • A61K2236/33Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones
    • A61K2236/331Extraction of the material involving extraction with hydrophilic solvents, e.g. lower alcohols, esters or ketones using water, e.g. cold water, infusion, tea, steam distillation, decoction
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K2236/00Isolation or extraction methods of medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicine
    • A61K2236/50Methods involving additional extraction steps
    • A61K2236/53Liquid-solid separation, e.g. centrifugation, sedimentation or crystallization

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
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  • Microbiology (AREA)
  • Medical Informatics (AREA)
  • Botany (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Inorganic Chemistry (AREA)
  • Medicines Containing Plant Substances (AREA)
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Abstract

The invention provides a composition with function of alleviating asthenopia. The composition with function of alleviating asthenopia is prepared from the following substances in parts by weight: 10-60 parts of a bilberry extract, 5-20 parts of a wolfberry extract, 5-20 parts of an extract of semen cassiae, 5-20 parts of an extract of marigold flower, 5-20 parts of rose condensed juice and 5-40 parts of an aloe extract. The composition has the advantages that an effect of treating and alleviating asthenopia is achieved; on the basis of utilizing a bilberry extract and a wolfberry extract as active ingredients in the existing composition, the extract of semen cassiae, the extract of marigold flower, the rose condensed juice and the aloe extract are additionally added and are capable of achieving a synergistic effect, so that the composition provided by the invention has a favorable health efficacy of alleviating asthenopia.

Description

A kind of have the compositions alleviating asthenopia function
Technical field
The invention belongs to field of medicaments, be specifically related to composition and the preparation side of a kind of compositions alleviating asthenopia function Method.
Background technology
At present, in modern society, due to TV and the general and increase with life stress that works of computer, cause eyes Tired and relevant eye class disease increases day by day.Asthenopia is also known as eyestrain, and asthenopia is owing to excess eye-using (including: read Official documents and correspondence, operating computer, surf the Net, see the factor such as TV, driving) and environmental factors (dry, air conditioner surroundings etc.) cause A series of eyes malaise symptoms, mainly show as that eyes are dry and astringent, the acid of foreign body sensation, blurred vision, eyes is swollen.Give by Pericarpium Citri tangerinae Extract and Fructus Lycii molecular eye care medicine, but figure place is less, fail to use widely and have soothing the liver, improving eyesight and clear away heart-fire merit The Chinese crude drug of energy, to give full play to Chinese crude drug synergism raising curative effect in treatment and health care.
Summary of the invention
The purpose of the present invention is aiming at above-mentioned deficiency, and provides a kind of compositions having and alleviating asthenopia function.
The present invention is mainly made up of the material of following parts by weight: Pericarpium Citri tangerinae extract 10-60 weight portion, wolfberry fruit extract 5-20 weight portion, Semen Cassiae extract 5-20 weight portion, marigold flower extract 5-20 weight portion, Flos Rosae Rugosae concentrated juice 5-20 Weight portion and Aloe extract 5-40 weight portion composition.
Pericarpium Citri tangerinae extract therein requires the % Han anthocyanidin >=20.0.
Mainly it is made up of the material of following parts by weight: Pericarpium Citri tangerinae extract 40 weight portion, wolfberry fruit extract 10 weight Part, Semen Cassiae extract 10 weight portion, marigold flower extract 10 weight portion, Flos Rosae Rugosae concentrated juice 10 weight portion, Aloe are extracted Thing 25 weight portion forms.
By Pericarpium Citri tangerinae extract 10-60 weight portion, wolfberry fruit extract 5-20 weight portion, marigold flower extract 5-20 weight The conventional oral dosage formulations that amount part, Aloe extract 5-40 weight portion and the acceptable adjuvant of pharmaceutics are prepared by mixing into.
Described adjuvant include lactose 1-4 weight portion, mannitol 2-10 weight portion, aspartame 0.5-2 weight portion, Sodium carboxymethyl cellulose 0.5-2 weight portion.
Comprise the steps:
(1) taken Aloe is cut fritter, after smashing to pieces, add isopyknic distilled water, at 20 DEG C, ultrasonic cell disruption instrument enters Row is broken, centrifugal, filters;Filtrate adds the stirring of equal-volume ethanol, places 24 hours, then machine is centrifuged by centrifugation, abandoning supernatant, Precipitation washing with alcohol, sucking filtration is dried, and obtains Aloe extract standby;
(3) Pericarpium Citri tangerinae extract 10-60 weight portion, wolfberry fruit extract 5-20 weight portion, Semen Cassiae extract 5-20 weight are taken Part, marigold flower extract 5-20 weight portion, Flos Rosae Rugosae concentrated juice 5-20 weight portion and Aloe extract 5-40 parts by weight of crushed The conventional oral dosage formulations that adjuvant acceptable with pharmaceutics is prepared by mixing into.
Pericarpium Citri tangerinae: for Ericaceae Vaccinium fallen leaves or evergreen shrubs, fruit is berry, blue or red, subcircular.Wherein Blue fruit Pericarpium Citri tangerinae is commonly called as blue berry.Blue berry is the wild plant that a kind of tolerance to cold is extremely strong, and China mainly produces in Xing'anling mountains forest zone. The U.S., Canada, Japan and other countries are set to functional food and health product blue berry, are favored by people.According to the U.S., day This and the research of Europe scholar, often edible blue berry goods, can vision enhancing, anti-eye strain significantly.Pericarpium Citri tangerinae contains Anthocyanidin.
The critical function of anthocyanidin is activation and the resynthesis effect promoting erythropsin, thus improves eye and regard acuity, Accelerate dark surrounds and adapt to ability.Anthocyanidin also is able to be effectively improved myopia vulnerable period, in early days myopia and the hypermetropia of low myopia Power situation, effective percentage reaches 77.12%, but this improvement is typically in the range of 2-3 row (logarithmic visual acuity chart).Week is light preferably etc. to be also demonstrated Pericarpium Citri tangerinae extract compound vitamin A can improve vision, alleviates asthenopia, puies forward eyes duration of photopic vision, hence it is evident that improve ophthalmic bloated, Ophthalmalgia, photophobia, regarding dry and astringent.
Fructus Lycii: property is put down, and sweet in the mouth, returns liver, kidney channel.There is effect of tonifying liver, kidney tonifying, improving eyesight.Compendium of Material Medica is recorded: " Chinese holly Qi, kidney-tonifying sperm-generating, nourishing the liver, improving eyesight, hard muscles and bones, fatigue taking away, easy color, bleach, improving eyesight is calmed the nerves, and makes us long-lived ".Fructus Lycii and ten thousand longevity Flos Chrysanthemi compatibility, can the oculopathy that causes for the treatment of the liver void, as seen, distinguished and admirable tear, nebula hide the disease such as eyeball, cataract.
Semen Cassiae: bitter in the mouth, sweet, salty, cold nature, enter liver, kidney, large intestine channel;Loosening bowel to relieve constipation, blood fat reducing improving eyesight, treatment constipation and Hyperlipidemia, hypertension.Liver heat removing and eyesight improving, diuretic relieving constipation, there are laxative action, reducing blood pressure and blood fat.
Marigold flower: property is pungent, sweet in the mouth, hardship, it is slightly cold, returns liver, lung meridian.There is the merit of liver heat removing and eyesight improving, heat-clearing and toxic substances removing, dispelling wind and heat pathogens Effect.The headache conjunctival congestion that causes for disturbing upward of liver-fire, regarding diseases such as thing mistake flowers." book on Chinese herbal medicine justice " claim " poor fall is let out, can receive take the photograph void positive and Receive under being attributed to, therefore be mesh section key medicine ".
Flos Rosae Rugosae: sweet in the mouth, warm in nature, fragrant odour, mild in medicine property and, toxin expelling, and blood dissipating blood stasis, blood stasis dispelling of having one's ideas straightened out, soothing the liver be amusing, promote Enter bile secretion, help digest, regulation mechanism.
Aloe: nature and flavor are bitter, cold, enter liver, the heart, spleen channel.Can heat clearing away, relieving constipation.Compendium of Material Medica is recorded: " improving eyesight relieving palpitation ".
The method have the advantages that: the present invention has treatment and alleviates asthenopic effect, existing with Pericarpium Citri tangerinae extract with Chinese holly On the basis of Qi extract is active component, increase Semen Cassiae extract, marigold flower, Flos Rosae Rugosae concentrated juice and Aloe extract, Serve the effect of Synergistic, have and preferably alleviate asthenopic health-care effect.
Detailed description of the invention
The present invention is mainly made up of the material of following parts by weight: Pericarpium Citri tangerinae extract 10-60 weight portion, wolfberry fruit extract 5-20 weight portion, Semen Cassiae extract 5-20 weight portion, marigold flower extract 5-20 weight portion, Flos Rosae Rugosae concentrated juice 5-20 Weight portion and Aloe extract 5-40 weight portion composition.
Pericarpium Citri tangerinae extract therein requires the % Han anthocyanidin >=20.0.
Mainly it is made up of the material of following parts by weight: Pericarpium Citri tangerinae extract 40 weight portion, wolfberry fruit extract 10 weight Part, Semen Cassiae extract 10 weight portion, marigold flower extract 10 weight portion, Flos Rosae Rugosae concentrated juice 10 weight portion, Aloe are extracted Thing 25 weight portion forms.
By Pericarpium Citri tangerinae extract 10-60 weight portion, wolfberry fruit extract 5-20 weight portion, marigold flower extract 5-20 weight The conventional oral dosage formulations that amount part, Aloe extract 5-40 weight portion and the acceptable adjuvant of pharmaceutics are prepared by mixing into.
Described adjuvant include lactose 1-4 weight portion, mannitol 2-10 weight portion, aspartame 0.5-2 weight portion, Sodium carboxymethyl cellulose 0.5-2 weight portion.
Comprise the steps:
(1) taken Aloe is cut fritter, after smashing to pieces, add isopyknic distilled water, at 20 DEG C, ultrasonic cell disruption instrument enters Row is broken, centrifugal, filters;Filtrate adds the stirring of equal-volume ethanol, places 24 hours, then machine is centrifuged by centrifugation, abandoning supernatant, Precipitation washing with alcohol, sucking filtration is dried, and obtains Aloe extract standby;
(3) Pericarpium Citri tangerinae extract 10-60 weight portion, wolfberry fruit extract 5-20 weight portion, Semen Cassiae extract 5-20 weight are taken Part, marigold flower extract 5-20 weight portion, Flos Rosae Rugosae concentrated juice 5-20 weight portion and Aloe extract 5-40 parts by weight of crushed The conventional oral dosage formulations that adjuvant acceptable with pharmaceutics is prepared by mixing into.
Embodiment 1:
(1) take the Pericarpium Citri tangerinae extract 300g that buys in market, Fructus Lycii extract 35g, Semen Cassiae extract 35g, marigold flower carry Take thing 30g, Flos Rosae Rugosae concentrated juice 5g;
(2) take fresh Aloe and cut fritter, after smashing to pieces, add isopyknic distilled water, at 20 DEG C, ultrasonic cell disruption instrument is carried out Broken, centrifugal, filter.Filtrate adds the stirring of equal-volume ethanol, places 24 hours, then machine is centrifuged by centrifugation, and abandoning supernatant is heavy Shallow lake washing with alcohol, sucking filtration is dried, and obtains Aloe extract and takes out 35g;
(3) take adjuvant lactose 20 g, mannitol 60 g, aspartame 10g and sodium carboxymethyl cellulose 10g to pulverize, cross 100 mesh Sieve, prepares Powdered. lactose 20 g, powdery mannitol 60 g, powdery aspartame 10g and powdery sodium carboxymethyl cellulose 10g;
(4) by Powdered. lactose 20 g, powdery mannitol 60 g, powdery aspartame 10g, powdery sodium carboxymethyl cellulose 10g, reed Luxuriant growth extract 35g, Pericarpium Citri tangerinae extract 300g, Fructus Lycii extract 35g, Semen Cassiae extract 35g, marigold flower extract 30g Mix with Flos Rosae Rugosae concentrated juice 5g, add pvp and pelletize, 40 DEG C of drying, granulate, add appropriate bitterness masking agent and make 1000 Chewable tablet.
Embodiment 2:
(1) take the Pericarpium Citri tangerinae extract 180g that buys in market, Fructus Lycii extract 60g, Semen Cassiae extract 60g, marigold flower carry Take thing 6g, Flos Rosae Rugosae concentrated juice 8g.
(2) take fresh Aloe and cut fritter, after smashing to pieces, add isopyknic distilled water, at 20 DEG C in ultrasonic cell disruption instrument Crush, centrifugal, filter.Filtrate adds the stirring of equal-volume ethanol, places 24 hours, then machine is centrifuged by centrifugation, supernatant discarded Liquid, precipitation washing with alcohol, sucking filtration is dried, and obtains Aloe extract and takes out 100g.
(3) take adjuvant lactose 20 g, mannitol 60 g, aspartame 10g and sodium carboxymethyl cellulose 10g to pulverize, cross 100 Mesh sieve, prepares Powdered. lactose 20 g, powdery mannitol 60 g, powdery aspartame 10g and powdery sodium carboxymethyl cellulose 10g;
(4) by Powdered. lactose 20 g, powdery mannitol 60 g, powdery aspartame 10g, powdery sodium carboxymethyl cellulose 10g, reed Luxuriant growth extract 100g, Pericarpium Citri tangerinae extract 180g, Fructus Lycii extract 60g, Semen Cassiae extract 60g, marigold flower extract 6g Mix with Flos Rosae Rugosae concentrated juice 5g, add pvp and pelletize, 40 DEG C of drying, granulate, add appropriate bitterness masking agent and make 1000 Chewable tablet.
Embodiment 3:
(1) take market and buy commodity Pericarpium Citri tangerinae extract 280g, Fructus Lycii extract 30g, Semen Cassiae extract 30g, marigold flower Extract 30g, Flos Rosae Rugosae concentrated juice 5g.
(2) take fresh Aloe and cut fritter, after smashing to pieces, add isopyknic distilled water, at 20 DEG C in ultrasonic cell disruption instrument Crush, centrifugal, filter.Filtrate adds the stirring of equal-volume ethanol, places 24 hours, then machine is centrifuged by centrifugation, supernatant discarded Liquid, precipitation washing with alcohol, sucking filtration is dried, and obtains Aloe extract and takes out 60g.
(3) take adjuvant lactose 20 g, mannitol 60 g, aspartame 10g and sodium carboxymethyl cellulose 10g to pulverize, cross 100 Mesh sieve, prepares Powdered. lactose 20 g, powdery mannitol 60 g, powdery aspartame 10g and powdery sodium carboxymethyl cellulose 10g;
(4) by Powdered. lactose 20 g, powdery mannitol 60 g, powdery aspartame 10g, powdery sodium carboxymethyl cellulose 10g, reed Luxuriant growth extract 60g, Pericarpium Citri tangerinae extract 280g, Fructus Lycii extract 30g, Semen Cassiae extract 30g, marigold flower extract 30g Mix with Flos Rosae Rugosae concentrated juice 5g, add pvp and pelletize, 40 DEG C of drying, granulate, add appropriate bitterness masking agent and make 1000 Chewable tablet.
Embodiment 4:
(1) the commodity Pericarpium Citri tangerinae extract 240g of market purchase, Fructus Lycii extract 50g, Semen Cassiae extract 50g, Flos Tagetis Erectae are taken Flower extract 50g, Flos Rosae Rugosae concentrated juice 5g.
(2) take fresh Aloe and cut fritter, after smashing to pieces, add isopyknic distilled water, at 20 DEG C in ultrasonic cell disruption instrument Crush, centrifugal, filter.Filtrate adds the stirring of equal-volume ethanol, places 24 hours, then machine is centrifuged by centrifugation, supernatant discarded Liquid, precipitation washing with alcohol, sucking filtration is dried, and obtains Aloe extract and takes out 60g,
(3) take adjuvant lactose 20 g, mannitol 60 g, aspartame 10g and sodium carboxymethyl cellulose 10g to pulverize, cross 100 mesh Sieve, prepares Powdered. lactose 20 g, powdery mannitol 60 g, powdery aspartame 10g and powdery sodium carboxymethyl cellulose 10g;
(4) by Powdered. lactose 20 g, powdery mannitol 60 g, powdery aspartame 10g, powdery sodium carboxymethyl cellulose 10g, reed Luxuriant growth extract 60g, Pericarpium Citri tangerinae extract 240g, Fructus Lycii extract 50g, Semen Cassiae extract 50g, marigold flower extract 50g Mix with Flos Rosae Rugosae concentrated juice 5g, add pvp and pelletize, 40 DEG C of drying, granulate, add appropriate bitterness masking agent and make 1000 Chewable tablet.

Claims (6)

1. one kind has the compositions alleviating asthenopia function, it is characterised in that: it is made up of the material of following parts by weight: more Fructus Citri tangerinae extract 10-60 weight portion, wolfberry fruit extract 5-20 weight portion, Semen Cassiae extract 5-20 weight portion, marigold flower carry Take thing 5-20 weight portion, Flos Rosae Rugosae concentrated juice 5-20 weight portion and Aloe extract 5-40 weight portion composition.
2. there is the compositions alleviating asthenopia function according to a kind of described in claim 1, it is characterised in that: therein more Fructus Citri tangerinae extract requires the % Han anthocyanidin >=20.0.
3. according to a kind of compositions with alleviation asthenopia function described in claim 1, it is characterised in that: by following heavy The material of amount number is made: Pericarpium Citri tangerinae extract 40 weight portion, wolfberry fruit extract 10 weight portion, Semen Cassiae extract 10 weight Part, marigold flower extract 10 weight portion, Flos Rosae Rugosae concentrated juice 10 weight portion, Aloe extract 25 weight portion composition.
4. according to a kind of compositions with alleviation asthenopia function described in claim 1, it is characterised in that: by following heavy The material of amount number is made;Pericarpium Citri tangerinae extract 10-60 weight portion, wolfberry fruit extract 5-20 weight portion, marigold flower extract 5-20 weight portion, Aloe extract 5-40 weight portion.
5. according to a kind of compositions with alleviation asthenopia function described in claim 4, it is characterised in that it also has lactose 1-4 weight portion, mannitol 2-10 weight portion, aspartame 0.5-2 weight portion, sodium carboxymethyl cellulose 0.5-2 weight portion.
6. a preparation method with the compositions alleviating asthenopia function, it is characterised in that comprise the steps:
(1) taken Aloe is cut fritter, after smashing to pieces, add isopyknic distilled water, at 20 DEG C, ultrasonic cell disruption instrument enters Row is broken, centrifugal, filters;Filtrate adds the stirring of equal-volume ethanol, places 24 hours, then machine is centrifuged by centrifugation, abandoning supernatant, Precipitation washing with alcohol, sucking filtration is dried, and obtains Aloe extract standby;
(3) Pericarpium Citri tangerinae extract 10-60 weight portion, wolfberry fruit extract 5-20 weight portion, Semen Cassiae extract 5-20 weight are taken Part, marigold flower extract 5-20 weight portion, Flos Rosae Rugosae concentrated juice 5-20 weight portion and Aloe extract 5-40 parts by weight of crushed The conventional oral dosage formulations that adjuvant acceptable with pharmaceutics is prepared by mixing into.
CN201610467974.XA 2016-06-24 2016-06-24 Composition with function of alleviating asthenopia Pending CN106038872A (en)

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Cited By (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106491947A (en) * 2016-11-18 2017-03-15 烟台新时代健康产业有限公司 A kind of composition for relieving asthenopia and its preparation
CN108095112A (en) * 2017-12-18 2018-06-01 苏州诺衡生命科技有限公司 One kind contributes to health food for relieving visual fatigues of health food and preparation method
CN111067098A (en) * 2019-12-16 2020-04-28 宁波君瑞生物科技有限公司 Solid preparation with eye health protection effect

Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102552639A (en) * 2012-02-15 2012-07-11 吉林修正药业新药开发有限公司 Traditional Chinese medicine possessing function for alleviating asthenopia and its preparation method

Patent Citations (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN102552639A (en) * 2012-02-15 2012-07-11 吉林修正药业新药开发有限公司 Traditional Chinese medicine possessing function for alleviating asthenopia and its preparation method

Cited By (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN106491947A (en) * 2016-11-18 2017-03-15 烟台新时代健康产业有限公司 A kind of composition for relieving asthenopia and its preparation
CN106491947B (en) * 2016-11-18 2019-11-26 烟台新时代健康产业有限公司 A kind of composition for relieving asthenopia and its preparation
CN108095112A (en) * 2017-12-18 2018-06-01 苏州诺衡生命科技有限公司 One kind contributes to health food for relieving visual fatigues of health food and preparation method
CN111067098A (en) * 2019-12-16 2020-04-28 宁波君瑞生物科技有限公司 Solid preparation with eye health protection effect

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Application publication date: 20161026