CN106038053B - Medicine-filling device after eyeball - Google Patents
Medicine-filling device after eyeball Download PDFInfo
- Publication number
- CN106038053B CN106038053B CN201610520825.5A CN201610520825A CN106038053B CN 106038053 B CN106038053 B CN 106038053B CN 201610520825 A CN201610520825 A CN 201610520825A CN 106038053 B CN106038053 B CN 106038053B
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- Prior art keywords
- syringe needle
- medicine
- support plate
- filling device
- screw thread
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Classifications
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/0008—Introducing ophthalmic products into the ocular cavity or retaining products therein
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61F—FILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
- A61F9/00—Methods or devices for treatment of the eyes; Devices for putting-in contact lenses; Devices to correct squinting; Apparatus to guide the blind; Protective devices for the eyes, carried on the body or in the hand
- A61F9/007—Methods or devices for eye surgery
- A61F9/00736—Instruments for removal of intra-ocular material or intra-ocular injection, e.g. cataract instruments
Abstract
The invention discloses medicine-filling devices after a bulb comprising syringe and epitheca, the syringe include injector cartridge, piston push rod, piston, the first protruding portion, the first syringe needle and the first support plate；The epitheca includes epitheca cylinder, the second protruding portion, the second syringe needle and the second support plate；It is wherein provided with internal screw thread on the distal side inner wall of epitheca cylinder, and is provided with external screw thread on the distal side outer wall of injector cartridge；The distal end of first syringe needle is blunt and the distal end of the second syringe needle is sharp；The distal portions of first syringe needle are equipped with one or more medicine-pouring ports；With one or more stomatas are provided on the bottom surface of epitheca cylinder.Using medicine-filling device after ball of the invention, the second syringe needle and the first syringe needle execute puncture and removing function respectively, and using the medicine-pouring port injection on the first syringe needle, can reach the multipurpose of active control injection site depth, injection amount and rate of administration simultaneously.
Description
Technical field
The present invention relates to a kind of eye medicine-filling devices, and in particular, to eye medicine-filling device after a bulb.
Background technique
Retrobulbar injection is that flesh cone after infusion of medicine eyeball is interior to reach treatment and anesthetic effect.The operation is mainly used for eye
The Ophthalmic ganglia blockage of interior operation is anaesthetized, the inflammation at eye rear portion, such as retrobulbar neuritis, choroiditis, the retinitis and view
Nethike embrane central artery obstruction, green light ophthalmagra person can also be used as the administration route of local treatment.
However, using conventional needles (such as syringe needle after 1.25 inches, 25 or 27G syringe needle or short inclined-plane, more blunt ball) into
Row retrobulbar injection needs more skilled operative skill.Even if having skilled operative skill, the inherent defect of conventional needles and
Complicated anatomical structure after ball, which makes retrobulbar injection still, has very important complication rate, becomes a wind
The dangerous higher medical care precess of degree.
Common retrobulbar injection complication includes：1) retrobulbar bleeding：Inserting needle too depth and syringe needle are very much sharp keen injure when injection
Blood vessel in socket of the eye shows as progressive exophthalmos, and fissura palpebrae cannot be closed, and socket of the eye pressure increases, subconjunctival hemorrhage or subcutaneous extvavasated blood.2) black
It is dim：Since needle point enters vagina nervi optici, injection of medicine excessively causes optic nerve oedema to be pressurized, and eyesight falls sharply or due to oppression eyeball
Cause arter centralis retinae spasm too long, leads to temporary amaurosis.3) eyeball compression reflex：Some patientss may occur in which eye in injection
Oculo cardiac reflex shows as decreased heart rate, and arrhythmia cordis is with dizzy, uncomfortable in chest, vomiting, perspiration etc..The reason is that patient's high-pressure or
Due to pressure is applied to eyeball.4) transient diplopia, strabismus, ptosis.5) eyelid subcutaneous hemorrhage：Needle point brushes up against hair when injection
Caused by thin blood vessel.6) eyelid, chemosis, bleeding：Eyelid and chemosis are mostly that medicine irritation causes vascular permeability to sexually revise institute
It causes；Eyelid and conjunctival hemorrhage are that syringe needle injures subcutaneously or conjunctiva thin vessels lead to subcutaneous extvavasated blood；Subconjunctival hemorrhage：Due to inserting needle mistake
Shallowly, caused by inserting needle position is improper or mismate causes drug to enter under bulbar conjunctiva.7) optic nerve injury：It is needle point too cutting edge of a knife or a sword
Benefit, inserting needle is too deep or needle angle is incorrect causes.8) arter centralis retinae, venous embolism：With hypertensive arteriosclerosis
Be people at highest risk with spiritual high-pressure person, when retrobulbar injection can lead to intraocular pressure increase cause arter centralis retinae, vein by
Pressure, causes strong ischemia；Patient's arteria carotis has patch formation, atherosis, vasopasm thrombus breaks loose to lead to retina
Central artery, venous embolism are formed.9) misoperation or injection needle are excessively sharp puncture eyeball, lead to intraocular drops, ball
Interior infection or intraocular drug toxic reaction etc..
Therefore, need to develop and design in the art it is a kind of easy to operate, it is highly-safe and can easily control inserting needle
Medicine-filling device after the ball of depth.
Summary of the invention
To solve the above problem in the prior art, the object of the present invention is to provide a kind of easy to operate, highly-safe
Medicine-filling device (below sometimes referred to as " medicine-filling device of the invention ") after ball.
Medicine-filling device includes after ball of the invention：Syringe and the epitheca for accommodating the syringe, the syringe include
It injector cartridge, piston push rod, piston, the first protruding portion, the first syringe needle and is surrounded at the proximal end of injector cartridge
First support plate of the injector cartridge setting；And the epitheca include epitheca cylinder, the second protruding portion, the second syringe needle with
And around the second support plate of epitheca cylinder setting at the proximal end of epitheca cylinder；Wherein in second support plate
It is equipped with groove, the groove is sized to enough receiving first support plates；In the distal side of the epitheca cylinder
Internal screw thread or external screw thread are provided on inner wall, and being provided on the distal side outer wall of the injector cartridge can be with the epitheca
The corresponding external screw thread or internal screw thread of the internal screw thread or external screw thread engagement on cylinder, and first support plate is by structure
It causes to rotate with direction identical with the screw-in direction of the external screw thread or internal screw thread on the syringe；Described first
Protruding portion be configured to protrude outward from the bottom surface of the injector cartridge and the distal end of first protruding portion with it is described
The connection of first syringe needle, and the distal end of first syringe needle is blunt；Second protruding portion is configured to from described outer
The bottom surface of sheath cylinder protrudes outward and the distal end of second protruding portion is connect with second syringe needle, and described second
The distal end of syringe needle is sharp；The length of first syringe needle is configured to greater than the length of second syringe needle and described the
The outer diameter of one syringe needle is less than the internal diameter of second syringe needle；The distal portions of first syringe needle are equipped with one or more injections
Mouthful；One or more stomatas are provided with on the bottom surface of the epitheca cylinder.
In the present invention, it is to be understood that external screw thread or internal screw thread on syringe to be threaded into direction unrestricted
System, can use right-handed thread or left hand thread.Therefore, mentioned above " first support plate be configured to
Direction identical with the screw-in direction of the external screw thread or internal screw thread on the syringe rotates " mean that user is operating
While the first support plate can be only pulled or rotated with finger, the direction pulled or rotated should be with the external screw thread on syringe
Or the screw-in direction of internal screw thread is identical, i.e. clockwise direction or left hand direction.
In the present invention, the essential structure of syringe and used material are unrestricted, can be using normal in this field
The ordinary syringe construction and common used material used is advised, as long as can be realized the purpose of injection.For example, injector cartridge,
The construction of the basic element of character such as piston push rod, piston, the first syringe needle can be using any money well known in the prior art in this field
The design of syringe；Manufacturing material used by the needle and syringe head after ball of the invention in medicine-filling device simultaneously can also benefit
With any suitable material known in state of the art, for example, medical plastic (such as Teflon, polyethylene, poly- third
Alkene, other conventional medical plastics etc.) or medical metal material (for example, medical steel, such as 304L medical stainless steel, other than medical steel
Other medical metals, metal alloy etc.) or their any combination.
In the present invention, in order to adapt to the anatomical structure of eyeball and the requirement of retrobulbar injection, the size of syringe can join
According to the common 5ml specification of syringe in market (generally, clinically range of the retrobulbar injection liquid volume in about 3- about 5ml), example
Such as, outer diameter can be 1.0cm~1.5cm, and internal diameter can be 0.8cm~1.2cm, and externally threaded crest height and tooth bottom height can be each
From for 0.5mm~1.5mm.Dimension of inner screw thread on epitheca and epitheca can size according to syringe and externally threaded tooth
It rises and is correspondingly configured with tooth bottom height, as long as can accommodate and support syringe and ensure the external screw thread on syringe and epitheca
Internal screw thread on cylinder engages and forms firm threaded connection.It is to be understood that the only conduct of above-mentioned numberical range
Example, the scope of the present invention are not limited to these specific example ranges, and those skilled in the art can be in disclosure according to the present invention
Hold and principle combination concrete application situation is suitably sized to select.
In the present invention, manufacture epitheca used by material it is unrestricted, can using with the material of syringe it is identical or
Similar material, as long as can be realized the purpose for accommodating syringe, ensuring the operation of syringe and firmly puncturing.It is preferred that
Ground, the considerations of for robustness and stability, the rigidity for manufacturing material used by epitheca can be greater than the material of syringe
Rigidity.As example, the construction of the components such as epitheca cylinder, second syringe needle can use medical plastic (such as Teflon, poly- second
Alkene, polypropylene, other conventional medical plastics etc.) or medical metal material (for example, medical steel, medical such as 304L medical stainless steel
Other medical metals other than steel, metal alloy etc.) or their any combination.
In the present invention, since ophthalmic injection device and syringe needle are generally more elongated, setting the first protruding portion and
The purpose of second protruding portion acts as the pedestal of syringe needle, can effectively disperse and be buffered in tissue application when syringe needle enters tissue
Reaction force in syringe needle root, while reducing the swing or shaking of fine needle, to improve the stability of syringe needle.Therefore,
In a preferred embodiment, the shape of the first protruding portion and the second protruding portion can be selected from taper, rectangle, hemispherical, half
Any one of elliposoidal, preferably taper or hemispherical.In the present invention, the material of the first protruding portion and the second protruding portion is manufactured
It is unrestricted, as long as reaching above-mentioned purpose.As example, (such as Teflon, polyethylene, can be gathered using medical plastic
Propylene, other conventional medical plastics etc.) or medical metal material (for example, medical steel, such as 304L medical stainless steel, medical steel with
Other outer medical metals, metal alloy etc.) or their any combination.
Preferably, for manufacturing the material of the first protruding portion and the second protruding portion and the material of the first syringe needle and the second syringe needle
It is identical to reach above-mentioned purpose, while avoiding due to different materials hardness and difference flexible and causing the machinery of junction strong
The risk of degree decline or easy fracture.It is highly preferred that the material of the first protruding portion is also identical as the material of injector cartridge, and second
The material of protruding portion is also identical as the material of epitheca cylinder.
In a preferred embodiment, the first protruding portion is preferably identical with the shape of the second protruding portion, in this way when
When being bonded in the groove of the first support plate the second support plate of screw-in with the second support plate, the first protruding portion can be with the second protruding portion
It is tightly bonded together, further increases the overall stability of device.
In a further preferred embodiment, under original state (that is, preparing state), the first support plate and the second support
Scheduled distance can be separated by between plate, it thus can between the bottom surface of injector cartridge and the distal side inner wall and bottom surface of epitheca cylinder
To form the first Room.Gas air, nitrogen etc., such as sterile sky of preferably sterile gas can be accommodated in the first interior
Gas or sterile nitrogen etc..First Room and the gas wherein accommodated and the one or more being arranged on epitheca cylinder bottom surface
Stomata can cooperate movement of the injector cartridge in epitheca cylinder, in order to avoid generated in the moving process of injector cartridge any
Influence mobile air resistance.
In a preferred embodiment, the preset distance between the first support plate and the second support plate in the initial state
The screwing length of external screw thread and internal screw thread can be less than or equal to.The purpose of this design be when the first support plate by turn into
When entering in the groove of the second support plate, the external screw thread on injector cartridge does not reach or reaches exactly to the internal screw thread of epitheca cylinder
End, else if the preset distance be greater than external screw thread and internal screw thread screwing length, it is excessive in the first support plate turn
In the case where, the external screw thread on injector cartridge may destroy epitheca cylinder.
In the present invention, it is preferred to which the material of the first support plate of manufacture is identical as injector cartridge material, second is manufactured
The material of fagging is identical as epitheca cylinder material.For the first support plate and the second support in medicine-filling device after ball of the invention
The shape of plate is not particularly limited, as long as easily rotating or pulling the first support plate convenient for user's finger.As
Example, the first support plate and/or the second support plate can use the rules such as circle, ellipse, rectangle, triangle, diamond shape, ship shape
Shape or other irregular shapes for being convenient for user's finger to pull or rotate.
In a preferred embodiment, internal screw thread and/or external screw thread have 2~6 threads, preferably 2~4 screw threads
Tooth, most preferably 3 threads.It is to be understood that screw thread mentioned in the present invention can be single thread and multi start thread, it is excellent
Single thread is selected, if using multi start thread, preferred double thread.It, should be according to the first syringe needle but in the case where multi start thread
The size of the position adjustment screw pitch of upper medicine-pouring port and the number of screw pitch.
In the present invention, the tooth form of screw thread is unrestricted, can use triangle thread well known in the art, rectangle spiral shell
The tooth forms such as line, circular thread, trapezoidal thread and saw-tooth thread, as long as can be realized stable threaded connection.
In addition, it will be understood by those skilled in the art that the selection of external screw thread and internal screw thread is unrestricted, for example, can be
External screw thread is set on injector cartridge, corresponding internal screw thread is set on epitheca cylinder, vice versa, as long as being capable of forming stabilization
Threaded connection and convenient for manufacture.
In medicine-filling device of the invention, second Room can have in syringe, wherein medicament to be injected can be accommodated.When
Under injection state, i.e., when the first syringe needle reaches predetermined position, user can push syringe piston push rod, will be wait infuse
It penetrates medicament and is injected into injection site from syringe.In the present invention, the type and form of medicament to be injected are unrestricted.Institute
Stating medicament can be drug, be also possible to the not sterile saline of drug containing, Ringer's solution, buffer, distilled water etc..Institute
The form for stating medicament can be solution, suspension, emulsion, ointment, gel-forming solution, gelling agent, can bioerosion it is poly-
Close object or non-bioerodible polymers, biodegradable polymers or non-biodegradable polymer, etc..In addition, described
Medicament is also possible to following dosage form：It can also be used as drug-reservoir after it is injected into injection site to exist to controllable
The form of release (for example, sustained release) discharges drug.
Pharmaceutical dosage form for injection may include the acceptable pharmaceutically active agents of one or more ophthalmology, and may be used also
To include one or more inactive drug excipients.The example of the pharmaceutically active agents includes anti-infective, including but not
It is limited to, antibiotic, antivirotic and antifungal agent；Antiabnormal reaction agent and mast cell stabilizers；Steroidal and non-steroidal anti-inflammatory
Agent (such as nepafenac)；Cyclooxygenase-2 inhibitors, for example, Cox-1 and Cox-2 inhibitor；The group of anti-infective and anti-inflammatory agent
It closes；Decongestant；Betimol, including but not limited to, adrenergic agent, beta-adrenergic blockers, α-adrenaline
Agonist, parasympathomimetics, anticholinesterase, carbonic anhydrase inhibitor and prostaglandin；The group of Betimol
It closes；Antioxidant；Nutritional supplement；For treating the drug of macular cystoid edema, for example, non-steroidal anti-inflammatory drugs；For treating
The drug of ARMD, for example, angiogenesis inhibitors and cellosolve；Wound regulator, for example, growth factor；Antimetabolite；Nerve
Protective agent, for example, Eliprodil；With for treating deutomerite disease (including but not limited to, ARMD, CNV, retinopathy, retina
Inflammation, uveitis, macular edema and glaucoma) inhibition angiogenesis steroids.
In a preferred embodiment, multiple medicine-pouring ports can be configured on the first syringe needle along the vertical of the first syringe needle
It is uniformly distributed to direction.In the present invention, the number of medicine-pouring port and arrangement mode are unrestricted.For example, multiple medicine-pouring ports can be with
Single, two row or multi-row are oppositely disposed on the longitudinal direction of the first syringe needle, or the alternately various forms such as distribution.According to purpose
2 or more medicine-pouring ports, preferably 3-6 injection can be set in purposes, the type of injection drug, injection amount and rate of administration
Mouthful.Under constant injection pressure, medicine-pouring port is more, and when injection more disperses the pressure of local organization, is not to concentrate on
One or two point avoids the hypertonia at local a single point and the raising of socket of the eye pressure or vascular compression is caused to generate oedema.Separately
Outside, the design of this multiple medicine-pouring ports can make drug be injected at multiple positions in inserting needle path, avoid drug in short-term
Between be accumulated in caused by some position to the instantaneous compressing of optic nerve and then cause blindness.
Preferably, the spacing between two neighboring medicine-pouring port can be equal to 1 lead (note of external screw thread or internal screw thread：?
In the case where single thread, 1 lead=1 screw pitch, in the case where double thread, 1 lead=2 screw pitch).
Therefore, in a preferred embodiment, the first syringe needle can be configured to since the position of original state
It rotates the first support plate and revolves and expose in the second syringe needle described in Shi Nengcong that turns around and expose at least one medicine-pouring port.Further excellent
In the embodiment of choosing, the first support plate can be configured to the first syringe needle for each revolution and expose at least one from the second syringe needle
A medicine-pouring port.In another further preferred embodiment, the first syringe needle can be configured to revolve when the first support plate
Enter when being bonded in the groove of the second support plate with the second support plate, all medicine-pouring ports on the first syringe needle are all exposed to the second syringe needle
Except.
Purposes of these above-mentioned designs are when the circle of threads turn one (that is, the first support plate rotation one enclose), syringe
Cylinder is distally advanced a lead, and at this moment the first syringe needle can expose from the second syringe needle, and expose at least one note
Medicine mouth, preferably a medicine-pouring port (note：Those skilled in the art can according to actual needs, design the number of the medicine-pouring port of exposing
Mesh), and per revolution, just expose another medicine-pouring port until the first support plate drops into the groove of the second support plate
In, all medicine-pouring ports all expose.The advantages of this design is, first can by presetting the length of the second syringe needle
To accurately control the depth of puncture；Secondly, after being punctured to the depth of needs, by the way that the first support plate to be rotated to different circles
Number, user not only can control the depth of needle of the first syringe needle, while can control the medicine-pouring port number exposed on the first syringe needle
Mesh, to achieve the purpose that active control injection site depth, injection amount and rate of administration simultaneously.
In a preferred embodiment, the first syringe needle or the second syringe needle can be with the first protruding portion or the second protruding portion
It is integrally formed.
In a further preferred embodiment, the first syringe needle or the second syringe needle and the first protruding portion or the second protruding portion can be with
It is detachably connected.The advantages of this embodiment, is that the syringe needle of different sizes, different size can be used, for example, different
Length, different diameters, different number of medicine-pouring port, different medicine-pouring port arrangement mode etc., as long as keeping above-mentioned skill
Art feature is (for example, the length of the first syringe needle is longer than the length of the second syringe needle；The outer diameter of first syringe needle is less than in the second syringe needle
Diameter；The distal end of first syringe needle is blunt；The distal end of second syringe needle be point etc.) and realize above-mentioned purpose and technology
Effect.
In a preferred embodiment, the first support plate is equipped with the gyrobearing for being used to indicate first support plate
Label, such as arrow mark.In a further preferred embodiment, the second support plate is equipped with and is used to indicate the first support
The aid mark of the gyrobearing of plate, such as arrow mark.In the present invention, the label being used to indicate can be set
Any position in one support plate, and the aid mark being used to indicate can be set in the second support plate with described first
At the corresponding position of the label being used to indicate in support plate.The combination of the label and the aid mark can be used for referring to
Show whether the first support plate has rotated a circle or half-turn, so that instruction user there are several medicine-pouring ports to be exposed to the second syringe needle indirectly
Approximate location locating for the outer and distal end of the first syringe needle.
In the present invention, the length of the first syringe needle and the second syringe needle can be previously according to eye anatomy and clinical experience
To determine.Preferably, the length of the second syringe needle can be set as being less than the distance that margo orbitalis China and foreign countries 1/3 are bored to flesh, such second needle
The probability that head punctures sclera substantially reduces；The length of the first syringe needle is set as to bore as deep as flesh after stretching out from the second syringe needle simultaneously
And further to the injection site near sclera.Be attached on the sclera after temporal limbus corneae at 6.9mm due to musculus rectus lateralis and
The a length of 40.6mm of flesh (referring to ophthalmology, the second edition, People's Health Publisher, the first edition of in August, 2005, page 78), therefore flesh
The substantially linear distance of pitch cone radius temporal limbus corneae is calculated as 47.5mm.In view of the first syringe needle inserting needle path and non-rectilinear away from
From, therefore the maximum length of the first syringe needle is not preferably greater than 50mm, length range can be 47.5mm-50mm.
In the present invention, the outer diameter and inner diameter of the first syringe needle and the second syringe needle is referred to the size of conventional needles, for example,
Outer diameter can be 16G~30G (such as 1.16mm~0.16mm), the model of preferably 19G~25G (for example, 0.7mm~0.26mm)
It encloses.In addition, the outer diameter of the first syringe needle is less than the internal diameter of the second syringe needle, degree is unrestricted, as long as can ensure that the first syringe needle
It can easily be stretched out from the second syringe needle and guarantee that the strength and stiffness of the first syringe needle are enough to generate removing in ocular tissue
Effect.
In one embodiment, epitheca cylinder (various can be suitable for by transparent material for example, well known in the art
Medical transparent plastic material, high molecular material or glass) made of, the purpose is to allow user that can penetrate epitheca cylinder
See the position of syringe piston, the scale on the amount of liquid and syringe that accommodate in syringe.
Beneficial effects of the present invention
1. medicine-filling device after ball through the invention executes puncture procedure using the tip of the second syringe needle, utilizes the first needle
The blunt nosed carry out strip operation of head, thus considerably reduces prior art syringe needle and is easy to puncture the wind of blood vessel or surrounding tissue
Danger, reduces the incidence of complication.
2. by the length for presetting the second syringe needle, so that the depth of needle of the second syringe needle can not reach sclera, because
This is also greatly lowered the damage probability of the tip of the second syringe needle, can also significantly reduce relevant to vascular tissue injury
The incidence of complication.
3. after the stretching of the first syringe needle, can use the first syringe needle since the depth of needle of the second syringe needle is before flesh cone
It is blunt nosed that predetermined injection site is reached by strip operation, it further reduced the incidence of damage complication.
4. user can use the first support plate of rotation to control after being punctured to the depth of needs using the second syringe needle
The depth of needle of first syringe needle, while can control the medicine-pouring port number exposed on the first syringe needle, it is actively controlled to reach simultaneously
The multipurpose of injection site depth processed, injection amount and rate of administration.
5. using multiple medicine-pouring port injections, to the pressure of local organization to keep away when can not only disperse injection
The local pressure exempted from single injection point is excessively high, and multiple positions of the drug injection in inserting needle path can be avoided
Drug concentrates on some position, thus effectively avoids local pressure is excessively high local edema or drug part Rapid Accumulation is caused to be oppressed
Optic nerve causes the complication of blindness.
Detailed description of the invention
Fig. 1 be ball of the invention after medicine-filling device an embodiment structural schematic diagram.
Fig. 2A -2B be Fig. 1 in ball after medicine-filling device the distal side inner wall of epitheca cylinder and the distal side of injector cartridge outside
The schematic diagram of wall, wherein Fig. 2A shows the internal screw thread being located on epitheca cylinder inboard wall, and Fig. 2 B, which is shown, is located at injector cartridge
External screw thread on outer wall.
Fig. 3 shows the state that the first syringe needle of medicine-filling device after the ball of Fig. 1 exposes from the second syringe needle.
Fig. 4 is the bottom view of the epitheca cylinder bottom surface of medicine-filling device after the ball in Fig. 1, is shown and is located at epitheca cylinder
Stomata on bottom surface.
Fig. 5 A-5C is enlarged view of the proximal part under different conditions of medicine-filling device after the ball in Fig. 1, wherein Fig. 5 A
For first state, that is, original state schematic diagram, Fig. 5 B is the second state, i.e. the first support plate has been pulled a state when circle
Schematic diagram, Fig. 5 C be the third state, i.e. the schematic diagram that the first support plate falls into the state in the groove of the second support plate.
Fig. 6 A-6B be different conditions under Fig. 1 ball after the first support plate of medicine-filling device and the top view of the second support plate,
Wherein Fig. 6 A shows the top view under original state；Fig. 6 B shows the schematic diagram of the first support plate of rotation, the bending in figure
Arrow represents the direction of the first support plate rotation.
The schematic diagram of four kinds of states of medicine-filling device after the ball that Fig. 7 A-7D is Fig. 1, wherein Fig. 7 A is original state or preparation
State；Fig. 7 B is intermediate working condition, and Fig. 7 B is state when the first support plate is pulled a circle, and Fig. 7 C is maximum functional shape
State, the first support plate is fallen into the groove of the second support plate at this time；Fig. 7 D is injection state.
Fig. 8 A-8E is the operating procedure schematic diagram that injection operation is carried out using the retrobulbar injection device of Fig. 1.
Appended drawing reference：
Medicine-filling device after 1 ball of the invention
2 epitheca cylinders
3 injector cartridges
4 second syringe needles
5 first syringe needles
6 second protruding portions
7 first protruding portions
8 second support plates
9 first support plates
10 pistons
11 stomatas
12 medicine-pouring ports
13 second Rooms
Room 14 first
15 external screw threads
16 internal screw threads
17 grooves
18 piston push rods
19 first support plate marker arrows
20 second support plate marker arrows
Specific embodiment
The preferred embodiments of the invention are described with reference to the accompanying drawing, it will be understood by those skilled in the art that be below with reference to
Embodiment described in attached drawing or embodiment, which are merely to illustrate, realizes preferred forms of the invention, rather than by model of the invention
It encloses and is limited to these embodiments.The present invention can make various modifications and variations on the basis of following embodiments.These change
It is included within the scope of the present invention into variation.
Definition
Distal side or distal end：In the present specification, when description the device of the invention refers to " distal side or distal end ", which is
Refer to far from user or the close side from syringe needle.
Nearside or proximal end：In the present specification, when description the device of the invention refers to " nearside or proximal end ", which is
Refer to close to user or far from the side of syringe needle.
Screw thread：Refer on cylinder or conical surface, be formed by the continuous protrusion with regulation tooth form along helix,
Its protrusions refers to the entity part between two sides of screw thread, and also known as tooth is (referring to national technical standard, screw thread term GB/T
14791-93)。
Helix：Along the track for the point that cylinder or conical surface move, the axial displacement of the point and corresponding angular displacement
Cheng Ding ratio (referring to GB/T 14791-93).
External screw thread：Refer to and be formed by screw thread on cylinder or external conical surface (referring to GB/T 14791-93).
Internal screw thread：Refer to and be formed by screw thread on cylinder or tapered interior surface (referring to GB/T 14791-93).
Single thread：Refer to and be formed by screw thread along a helix (referring to GB/T 14791-93).
Right-handed thread：Refer to the screw thread screwed in when rotating clockwise (referring to GB/T 14791-93).
Left hand thread：Refer to the screw thread screwed in when rotation counterclockwise (referring to GB/T 14791-93).
Crest is high：Refer on form of thread, by crest along perpendicular to axis of thread direction to middle line distance (referring to
GB/T 14791-93)。
Tooth bottom is high：Refer on form of thread, by tooth bottom along perpendicular to axis of thread direction to middle line distance (referring to
GB/T 14791-93)。
Thread height：Refer on form of thread, crest is to tooth bottom perpendicular to the distance on axis of thread direction.
Screw pitch：Adjacent two tooth corresponds to the axial distance of point-to-point transmission on middle line, in short, first tooth of screw thread and
The axial distance of two teeth.
Lead：Adjacent two tooth corresponds to the axial distance of point-to-point transmission on middle line on same helix, in short, being exactly spiral shell
Line revolves the moved axial distance that turns around.If screw thread is single line or one start screw, screw pitch is equal with lead, if screw thread
It is two-wire or double thread, then lead is twice of screw pitch, and so on.
Tooth form：On the section by the axis of thread, the chamfered shape of screw thread (referring to GB/T 14791-93).
Screwing length：Length of thread engagement is that threadingly axis direction mutually screws part to two mutually matched screw threads
Length (referring to GB/T 14791-93).
Diameter：The definition of diameter is arrived by a planar graph or solid (such as circle, conic section, ball, cube) center
The distance of point-to-point transmission on side.Herein, diameter refers to the maximum length for referring to object.Object with irregular shape is come
It says, diameter is the length of the longest cross section of the object.In addition, herein, if diameter refers both to without otherwise indicated
Outer diameter.
Fig. 1 is structural schematic diagram of the embodiment under preparation state of medicine-filling device after ball of the invention.In Fig. 1
In, medicine-filling device 1 includes after ball：Syringe and the epitheca for accommodating syringe, the syringe includes injector cartridge 3, piston
Push rod 18, piston 10, the first protruding portion 7, the first syringe needle 5 and at the proximal end of injector cartridge 3 surround syringe cylinder
The first support plate 9 that body 3 is arranged；And epitheca includes epitheca cylinder 2, the second protruding portion 6, the second syringe needle 4 and in epitheca cylinder
The second support plate 8 being arranged at the proximal end of body 2 around epitheca cylinder 2；Groove 17 is wherein equipped in the second support plate 8,
The groove 17 is sized to the first support plate 9 of enough receivings；Interior spiral shell is provided on the distal side inner wall of epitheca cylinder 2
Line 16, and the corresponding external screw thread 15 that can be engaged with internal screw thread 16 is provided on the distal side outer wall of injector cartridge, and
And first support plate 9 be configured to rotate with direction identical with the screw-in direction of external screw thread 15；First protruding portion 7 is from note
The bottom surface of emitter cylinder 3 protrudes outward and the distal end of the first protruding portion 7 is connect with the first syringe needle 5, and the first syringe needle 5
Distal end is blunt；Second protruding portion 6 protruded outward from the bottom surface of epitheca cylinder 2 and the distal end of the second protruding portion 6 with
The connection of second syringe needle 4, and the distal end of the second syringe needle 4 is sharp；The length of first syringe needle 5 is greater than the length of the second syringe needle 4
Internal diameter of the outer diameter of degree and the first syringe needle 5 less than the second syringe needle 4；The distal portions of first syringe needle 5 are equipped with one or more injections
Mouth 12；With one or more stomatas 11 are provided on the bottom surface of epitheca cylinder 2.It can be seen in fig. 1 that the first protruding portion 7
It is identical with 6 shape of the second protruding portion, it is conical by its shape.In the bottom surface of injector cartridge 3 and the distal side inner wall of epitheca cylinder 2 and
The first Room 14 is formed between bottom surface, can accommodate gas, preferably filtrated air as the case may be in the first Room 14.It is using
In the case where aseptic gas, after aseptic gas being poured into during medicine-filling device after manufacturing ball of the invention, with through going out
The adhesive tape or plug seal stomata 11 of bacterium.Second Room 13 in syringe shown in Fig. 1 can accommodate medicine to be injected in advance
Agent, such as the gelling agent or gel-forming solution, sterile saline etc. of drug solution to be injected, drug containing.
After the ball of Fig. 1 in medicine-filling device 1, the length of the first syringe needle 5 is greater than the length (note of the second syringe needle 4：Needle length
In terms of the distance between needle point and the syringe needle root for being connected to protruding portion).It should be noted that the length of the first syringe needle 5 and the second syringe needle 4
Difference be at least greater than the distance between the medicine-pouring port of farthest side and the medicine-pouring port of recent side so that medicine-pouring port 12 can all from
Second syringe needle 4 exposes.
In Fig. 1, the first syringe needle 5 or the second syringe needle 4 and the first protruding portion 7 or the second protruding portion 6 can be one respectively
It is molding, it also can be respectively detachably connected.
Although should be understood that in Fig. 1, the first protruding portion 7 and the second protruding portion 6 are shown as conical projections, this hair
Bright to be not limited to this, first protruding portion of medicine-filling device and the second protruding portion can be using other shapes such as after ball of the invention
Rectangle, hemispherical, semielliptical shape etc., as described above.
Using single thread in medicine-filling device 1 after the ball of Fig. 1, therefore the lead and spiral shell of screw thread in this case
Away from equal.In Fig. 1, it is shown that external screw thread 15 has 3 threads, it is to be understood that, the invention is not limited thereto, this field skill
Art personnel can design 1,2 or 3 or more, preferably 2-6 thread according to specific needs.Form of thread in Fig. 1 is
Triangle, as described above, can also be using other tooth form rectangular thread, circular thread, trapezoidal thread and buttless threads etc.
Tooth form realizes that the present invention, the present invention do not have any restrictions to this.In addition, in Fig. 1, the first support plate 9 in the initial state
Preset distance between the second support plate 8 is equal to the screwing length (that is, 3 screw pitch) of external screw thread and internal screw thread.
Fig. 2A is the partial enlarged view of Fig. 1, shows the internal screw thread 16 on the distal side inner wall for being located at epitheca cylinder 2, figure
2B is the partial enlarged view of Fig. 1, shows the external screw thread 15 on the distal side outer wall for being located at injector cartridge 3.It should be appreciated that this
Invention is not limited to this, as described above, external screw thread can also be set on epitheca cylinder, and spiral shell in being arranged on injector cartridge
Line.3 medicine-pouring ports 12 are equipped on the first syringe needle 5 in addition, can see from Fig. 2 B, and this 3 medicine-pouring ports are in the first syringe needle 5
It is uniformly distributed on longitudinal direction.It is to be understood that number and arrangement side as described above, in the present invention, to medicine-pouring port 12
Formula is not particularly limited.
Fig. 3 shows the state that the first syringe needle 5 of medicine-filling device 1 after the ball of Fig. 1 exposes from the second syringe needle 4.The institute in Fig. 3
The state shown, external screw thread 15 have rotated a circle, at this time on the first syringe needle 5 medicine-pouring port 12 of farthest side from the second syringe needle 4
Expose, and other two medicine-pouring port 12 is still in the second syringe needle 4.It should be noted that in the present embodiment, two neighboring injection
Spacing between mouth 12 is equal to 1 lead of external screw thread 15 or internal screw thread 16, that is, a screw pitch.Furthermore, it is to be understood that such as
It is upper described, according to specific needs and application, can also be designed to when external screw thread 15 is revolved and turned around, on the first syringe needle 5 extremely
Few two medicine-pouring ports 12 expose from the second syringe needle 4.
Fig. 4 is the bottom view of the bottom surface of the epitheca cylinder 2 of medicine-filling device 1 after the ball in Fig. 1, is shown and is located at epitheca
Stomata 11 on the bottom surface of cylinder 2.Although showing two symmetrical stomatas 11 in Fig. 4, in practical applications, such as
It will be appreciated by persons skilled in the art that the number and arrangement mode of stomata 13 are unrestricted, as long as reaching the mesh of exhaust
?.
Enlarged view of the proximal part of medicine-filling device 1 under different conditions after the ball that Fig. 5 A-5C is Fig. 1.Fig. 5 A is shown
First state, that is, original state, in this case, the first support plate 9 is not rotated, at this time the first support plate 9 and the second support
Preset distance between plate 8 (precisely, with the groove 17 of the second support plate 8) is equal to screwing for external screw thread 15 and internal screw thread 16
Length (sees also Fig. 7 A)；Fig. 5 B shows the second state, and in this case, the first support plate 9, which is pulled, has rotated a circle；Figure
5C shows the third state, and in this case, the first support plate 9 is fallen into the groove 17 of the second support plate 8 after being rotated by 3 circles
And the bottom surface of the first support plate 9 is bonded that (note, in the present embodiment, 9 maximum of the first support plate can be with the top surface of groove 17
3 circle of rotation).
Fig. 6 A-6B is the first support plate 9 of medicine-filling device 1 and the vertical view of the second support plate 8 after the ball of Fig. 1 under different conditions
Figure.
Fig. 6 A shows the top view under original state, the visible side (right side in figure) in the first support plate 9 in figure
Label 19 equipped with arrow sample, and ipsilateral (right side in figure) in the second support plate is equipped with the aid mark 20 of arrow sample,
Label 19 and label 20 align at this time.It should be understood that as described above, the label 19 or aid mark 20 can be distinguished
Any position in first support plate 9 and the second support plate 8 is set.
Fig. 6 B shows the rotation of the first support plate 9, and the curved arrow in figure represents the direction of the first support plate 9 rotation.
It should be understood that although the direction of rotation shown in fig. 6b is clockwise, can also to use rotation counterclockwise
Turn direction.It should be noted that when using direction of rotation counterclockwise, in the design the screw thread side of external screw thread 15 and internal screw thread 16
To should accordingly change.
The combination of label 19 and label 20 shown in Fig. 6 A-6B can be used to indicate the rotation of the first support plate 9 to user
The orientation turned then illustrates user by the if label 19 is aligned again with label 20 after user rotates the first support plate 9
One support plate 9 has rotated a circle.Although the position grouping of the label 19 and label 20 that show in Fig. 6 A-6B is used to refer to first
Whether support plate 9 has rotated a circle, but the position of label 19 and label 20 can also be arranged and refer to when the two is aligned again
Show that the first support plate 9 has rotated at the position of half-turn.
It is also shown from Fig. 6 A-6B, the shape of the first support plate 9 and the second support plate 8 is ship shape.As long as described above,
Easily rotate or pull the first support plate convenient for user, the first support plate and/or the second support plate can also using it is round,
The shapes such as ellipse, rectangle, triangle, diamond shape.
The schematic diagram of four kinds of states of medicine-filling device 1 after the ball that Fig. 7 A-7D is Fig. 1.
Fig. 7 A is original state, and in this case, the first support plate 9 and the second support plate 8 are (precisely, with the at this time
The groove 17 of two support plates 8) between preset distance be equal to external screw thread 15 and internal screw thread 16 screwing length, at this point, the first needle
First 5 and medicine-pouring port 12 be hidden in the second syringe needle 4.
Fig. 7 B is intermediate working condition, and the first support plate 9 has been rotated a circle at this time, meanwhile, external screw thread 15 is also correspondingly
A circle is had rotated, the first syringe needle 5 is stretched out from the second syringe needle 4 at this time, and exposes the medicine-pouring port 12 of farthest side.In this embodiment party
In case, the first support plate 9 can also be rotated 2 circle (not shown), and two medicine-pouring ports 12 on such first syringe needle 5 are from
Expose in two syringe needles 4.
Fig. 7 C is maximum rating, and in this case, the first support plate 9 falls into the second support plate 8 after being rotated by 3 circles
Groove 17 in and the bottom surface of the first support plate 9 be bonded with the top surface of groove 17.At this point, the first protruding portion 7 and second is prominent
Portion 6 fits together, and the aseptic gas accommodated in the first Room 14 is discharged from stomata 11, and the first Room 14 disappears, while the first syringe needle 5
On three medicine-pouring ports 12 all expose from the second syringe needle 4.At this moment reach maximum rating.It is understood that institute here
The maximum rating of finger refers to the 1 attainable maximum rating of institute of medicine-filling device after ball, and not necessarily user is in reality
Final working condition when border operates.In practical applications, user can be according to specific needs (for example, injection is specific
Position, depth and injection amount etc.), determine final working condition, i.e., medicine-filling device 1 is in intermediate working condition still most after ball
Big working condition encloses number required for rotating the first support plate, subsequently into injection state (see below).
Fig. 7 D shows injection state, and in this case, user presses the piston push rod 18 of syringe, will be received in the
Medicament in two Room 13 is injected into required injection site, and after injection, second Room 13 disappears.
The foregoing describe an embodiment of medicine-filling device after ball of the invention original state, intermediate working condition,
Structure under maximum rating and injection state.It shows in Fig. 8 A-8E and is injected using the retrobulbar injection device 1 of Fig. 1
The operation chart of operation.Illustrate to utilize 1 injection of medicine-filling device operation of the invention shown in FIG. 1 below with reference to Fig. 8 A-8E
Illustrative steps：
Fig. 8 A：With the lower eyelid and upper skin of cheek under alcohol wipe patient at margo orbitalis, advise patient to watching attentively above nose, by the
Two syringe needles 4 (also can be under surface anesthesia, by fornix under temporo with the skin inserting needle of outer 1/3 intersection just above by socket of the eye lower edge 1/3
Portion's inserting needle).
Fig. 8 B：Inserting needle about 1cm is supported to orbital septum, and the second syringe needle 4 is slowly turned to direction on nose.
Fig. 8 C：After the second syringe needle 4 turns to above nose, keep epitheca cylinder 2 motionless with the hand for holding medicine-filling device 1, rotation
First support plate 9, and the label 19 in the first support plate 9 is observed, needed for reaching after circle number, observation ensures the first support plate 9
On label 19 be aligned with the label 20 in the second support plate 8, the first syringe needle 5 is stretched out from the second syringe needle 4 at this time.
Fig. 8 D：Continue on the slow inserting needle in direction on nose, pass through socket of the eye every enter muscle cone.
Fig. 8 E：After reaching in muscle cone, not in the blood vessels, pressing piston pushes away the needle point of pumpback and determining first syringe needle 5
The slow liquid medicine injection of bar 18.Medicine-filling device 1 is slowly extracted from former inserting needle direction after injection, and patient is advised to be closed eyelid, is used
Gauze is pinned, and is gently oppressed and is massaged eyeball at least 2 minutes, prevents retrobulbar bleeding.
Pay attention to：The maximum depth of needle of first syringe needle 5 is no more than 5cm.
The present invention includes non-limiting embodiments below：
1. medicine-filling device after a bulb, including：Syringe and the epitheca for accommodating the syringe, wherein the syringe packet
It includes injector cartridge, piston push rod, piston, the first protruding portion, the first syringe needle and is enclosed at the proximal end of injector cartridge
Around the first support plate of injector cartridge setting；And
The epitheca includes epitheca cylinder, the second protruding portion, the second syringe needle and encloses at the proximal end of epitheca cylinder
Around the second support plate of epitheca cylinder setting；
Groove is wherein equipped in second support plate, the groove is sized to enough receivings described first
Support plate；
Internal screw thread or external screw thread are provided on the distal side inner wall of the epitheca cylinder, and in the remote of the injector cartridge
Be provided on the outer wall of side can on the epitheca cylinder the internal screw thread or external screw thread engagement corresponding external screw thread or
Internal screw thread, and first support plate is configured to the rotation with the external screw thread or internal screw thread on the syringe
Enter the identical direction in direction to rotate；
First protruding portion is configured to protrude outward from the bottom surface of the injector cartridge and first protruding portion
Distal end connect with first syringe needle, and the distal end of first syringe needle is blunt；
Second protruding portion is configured to protrude outward from the bottom surface of the epitheca cylinder and second protruding portion
Distal end is connect with second syringe needle, and the distal end of second syringe needle is sharp；
The length of first syringe needle is configured to the outer diameter of length and first syringe needle greater than second syringe needle
Less than the internal diameter of second syringe needle；
The distal portions of first syringe needle are equipped with one or more medicine-pouring ports, preferably 3-6 medicine-pouring port；With
One or more stomatas are provided on the bottom surface of the epitheca cylinder.
2. medicine-filling device after ball described in embodiment 1, it is characterised in that first protruding portion and described second protrudes
The shape in portion is identical, and first protruding portion is configured to screw in the groove of second support plate when first support plate
In can be tightly bonded together with second protruding portion when being bonded with second support plate.
3. medicine-filling device after ball described in embodiment 1 or 2, it is characterised in that first protruding portion and described second is dashed forward
The shape in portion each is selected from any one of taper, rectangle, hemispherical, semielliptical shape, preferably taper or hemispherical out.
4. medicine-filling device after ball described in embodiment 1, it is characterised in that in the initial state, first support plate with
Predetermined distance between second support plate, thus in the bottom surface of the injector cartridge and the distal side of the epitheca cylinder
The first Room is formed between wall and bottom surface.
5. retrobulbar injection device described in embodiment 4, it is characterised in that the described first indoor receiving gas such as air,
Nitrogen etc., preferably sterile gas such as filtrated air or sterile nitrogen etc..
6. medicine-filling device after ball described in embodiment 4, it is characterised in that in the initial state first support plate with
The preset distance between second support plate is less than or equal to the screwing length of the external screw thread and the internal screw thread.
7. medicine-filling device after ball described in any one of embodiment 1-6, it is characterised in that the internal screw thread and/or outer spiral shell
Line has 2~5 threads, preferably 2~4 threads, most preferably 3 threads.
8. medicine-filling device after ball described in embodiment 1, it is characterised in that multiple medicine-pouring ports are configured to described first
Longitudinal direction on syringe needle along first syringe needle is uniformly distributed.
9. medicine-filling device after ball described in embodiment 8, it is characterised in that the spacing between the two neighboring medicine-pouring port
Equal to 1 lead of the external screw thread or the internal screw thread.
10. medicine-filling device after ball described in embodiment 4, it is characterised in that first syringe needle is configured to work as from initial
The position of state, which starts turning first support plate and revolves, exposes in the second syringe needle described in Shi Nengcong that turns around and exposes at least one
A medicine-pouring port.
11. medicine-filling device after ball described in any one of embodiment 1-10, it is characterised in that the first support plate quilt
It is configured to first syringe needle for each revolution and exposes at least one medicine-pouring port from second syringe needle.
12. medicine-filling device after ball described in any one of embodiment 1-11, it is characterised in that first syringe needle is by structure
It causes when being bonded in the groove that first support plate screws in second support plate with second support plate, described first
All medicine-pouring ports on syringe needle are all exposed to except second syringe needle.
13. medicine-filling device after ball described in any one of embodiment 1-12, it is characterised in that first syringe needle and institute
It is integrally formed that the first protruding portion and/or second syringe needle, which are stated, with second protruding portion.
14. medicine-filling device after ball described in any one of embodiment 1-12, it is characterised in that first syringe needle and institute
It states detachably connected the first protruding portion or second syringe needle and second protruding portion is detachably connected, or both
Combination.
15. medicine-filling device after ball described in any one of embodiment 1-14, it is characterised in that in first support plate
It is equipped with the label for being used to indicate the gyrobearing of first support plate, such as arrow mark.
16. medicine-filling device after ball described in any one of embodiment 1-15, it is characterised in that in second support plate
It is equipped with the aid mark for being used to indicate the gyrobearing of first support plate, such as arrow mark.
17. medicine-filling device after ball described in any one of embodiment 1-16, it is characterised in that the epitheca cylinder be by
Made of transparent material.
The present invention is illustrated by specific embodiment and embodiment above, but it is evident that without departing substantially from this
Under the premise of the spirit and scope of invention, those skilled in the art can make various changes to above-mentioned specific embodiment, and
And these changes are intended to be included within the scope of the present invention.
Claims (22)
1. medicine-filling device after a bulb, including：Syringe and the epitheca for accommodating the syringe, it is characterised in that
The syringe includes injector cartridge, piston push rod, piston, the first protruding portion, the first syringe needle and in syringe cylinder
Around the first support plate of injector cartridge setting at the proximal end of body；And
The epitheca includes epitheca cylinder, the second protruding portion, the second syringe needle and surrounds institute at the proximal end of epitheca cylinder
State the second support plate of epitheca cylinder setting；
Groove is wherein equipped in second support plate, the groove is sized to enough receivings first support
Plate；
Internal screw thread or external screw thread are provided on the distal side inner wall of the epitheca cylinder, and outside the distal side of the injector cartridge
Being provided on wall can be with the corresponding external screw thread or interior spiral shell of the internal screw thread or external screw thread engagement on the epitheca cylinder
Line, and first support plate is configured to the screw-in side with the external screw thread or internal screw thread on the syringe
It is rotated to identical direction；
First protruding portion be configured to protrude outward from the bottom surface of the injector cartridge and first protruding portion it is remote
Side end is connect with first syringe needle, and the distal end of first syringe needle is blunt；
Second protruding portion is configured to protrude outward from the bottom surface of the epitheca cylinder and the distal side of second protruding portion
End is connect with second syringe needle, and the distal end of second syringe needle is sharp；
The length of first syringe needle is configured to greater than the length of second syringe needle and the outer diameter of first syringe needle is less than
The internal diameter of second syringe needle；
The distal portions of first syringe needle are equipped with one or more medicine-pouring ports；With
One or more stomatas are provided on the bottom surface of the epitheca cylinder.
2. medicine-filling device after ball described in claim 1, it is characterised in that the distal portions of first syringe needle are equipped with 3-6 note
Medicine mouth.
3. medicine-filling device after ball described in claim 1, it is characterised in that first protruding portion and second protruding portion
Shape is identical, and first protruding portion be configured to when first support plate screw in the groove of second support plate with
Second support plate can be tightly bonded together when being bonded with second protruding portion.
4. medicine-filling device after ball described in claim 1, it is characterised in that first protruding portion and second protruding portion
Shape each is selected from any one of taper, rectangle, hemispherical, semielliptical shape.
5. medicine-filling device after ball described in claim 1, it is characterised in that first protruding portion and second protruding portion
Shape is respectively taper or hemispherical.
6. medicine-filling device after ball described in claim 1, it is characterised in that in the initial state, first support plate with it is described
Predetermined distance between second support plate, thus the distal side inner wall of the bottom surface of the injector cartridge and the epitheca cylinder and
The first Room is formed between bottom surface.
7. medicine-filling device after ball as claimed in claim 6, it is characterised in that the described first indoor receiving gas.
8. medicine-filling device after ball as claimed in claim 7, it is characterised in that the gas is filtrated air or sterile nitrogen.
9. medicine-filling device after ball as claimed in claim 6, it is characterised in that in the initial state first support plate with it is described
The preset distance between second support plate is less than or equal to the screwing length of the external screw thread and the internal screw thread.
10. medicine-filling device after ball described in claim 1, it is characterised in that the internal screw thread and/or external screw thread have 2~5
Thread.
11. medicine-filling device after ball described in claim 1, it is characterised in that the internal screw thread and/or external screw thread have 2~4
Thread.
12. medicine-filling device after ball described in claim 1, it is characterised in that the internal screw thread and/or external screw thread have 3 screw threads
Tooth.
13. medicine-filling device after ball described in claim 1, it is characterised in that multiple medicine-pouring ports are configured in first syringe needle
On be uniformly distributed along the longitudinal direction of first syringe needle.
14. medicine-filling device after ball described in claim 13, it is characterised in that the spacing etc. between the two neighboring medicine-pouring port
In 1 lead of the external screw thread or the internal screw thread.
15. medicine-filling device after ball as claimed in claim 6, it is characterised in that first syringe needle is configured to work as from original state
Position start turning first support plate rotation and turn around and expose in the second syringe needle described in Shi Nengcong and expose at least one note
Medicine mouth.
16. medicine-filling device after ball described in claim 1, it is characterised in that first support plate is configured to for each revolution
First syringe needle exposes at least one medicine-pouring port from second syringe needle.
17. medicine-filling device after ball described in claim 1, it is characterised in that first syringe needle is configured to when described first
Fagging screws in when being bonded in the groove of second support plate with second support plate, all injections on first syringe needle
Mouth is all exposed to except second syringe needle.
18. medicine-filling device after ball described in claim 1, it is characterised in that first syringe needle and first protruding portion and/
Or second syringe needle and second protruding portion are integrally formed.
19. medicine-filling device after ball described in claim 1, it is characterised in that first syringe needle and first protruding portion are removable
Connect with unloading or second syringe needle and second protruding portion it is detachably connected, or both combination.
20. medicine-filling device after ball described in claim 1, it is characterised in that be equipped in first support plate and be used to indicate institute
State the label of the gyrobearing of the first support plate.
21. medicine-filling device after ball described in claim 1, it is characterised in that be equipped in second support plate and be used to indicate institute
State the aid mark of the gyrobearing of the first support plate.
22. medicine-filling device after ball described in any one of claim 1-21, it is characterised in that the epitheca cylinder is by transparent
Made of material.
Priority Applications (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610520825.5A CN106038053B (en) | 2016-07-05 | 2016-07-05 | Medicine-filling device after eyeball |
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| CN201610520825.5A CN106038053B (en) | 2016-07-05 | 2016-07-05 | Medicine-filling device after eyeball |
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| CN106038053A CN106038053A (en) | 2016-10-26 |
| CN106038053B true CN106038053B (en) | 2018-11-20 |
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN108478326B (en) * | 2018-05-03 | 2020-11-03 | 乐清市然景电气有限公司 | Transition tube for an injection medical device |
| CN108524100A (en) * | 2018-05-03 | 2018-09-14 | 张琦 | Auripuncture, Injection in Tympanic Cavity medical treatment device |
| CN111991624B (en) * | 2018-05-03 | 2024-01-30 | 张琦 | Function conversion module for injection medical device |
| CN109172140A (en) * | 2018-08-13 | 2019-01-11 | 张琦 | For the crossover connection in auripuncture, Injection in Tympanic Cavity medical device |
| CN112155850A (en) * | 2018-08-13 | 2021-01-01 | 张琦 | Anti-misoperation tympanic membrane puncture and intratympanic injection medical device |
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