CN1060083C - 肺结核丸药及其制备方法 - Google Patents
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Abstract
本发明涉及一种肺结核丸及其备方法,其配方为:砂仁9-10克,麻黄25-30克,紫苑20-40克,甘草10-15克,当归5-20克,黄芪20克,枇杷叶20-30克,金银花15-20克,建曲15-20克,山楂18-20克,川贝母10克,白芨15-20克,百部15克,麦冬18-20克,白芥子25-30克,五味子20克,雷米封、PS和/或利复平50-60片(0.5克/片),共制成120丸,每丸药9克。临床资料表明,本发明的肺结核丸地肺结核的治愈率高达86.78%,总有效率95.8%,愈后不复发,长期服用无毒副作用,无抗药性,对不同类型的患者和不同类型的肺结核皆显效。
Description
本发明涉及一种专治肺结核的中成丸药及其制备方法。
西药治疗肺结核通常采用雷米封、对胺基水杨酸钠和/或利福平,长期取用后有毒副作用,会产生抗药性,愈后易复发。
本发明的目的在于开发一种对肺结核治愈率高的、愈后不复发的、毒副作用小且无抗药性的肺结核丸及其制备方法。
本发明的肺结核丸是一种组合物,原料药物组成如下:
砂仁9—10克,麻黄25—30克,紫苑20—40克,甘草10—15克,当归15—20克,黄芪20克,枇杷叶20—30克,金银花15—20克,建曲15—20克,山楂18—20克,川贝母10克,白芨15—20克,百部15克,麦冬18—20克,白芥子25—30克,五味子20克,雷米封、对胺基水杨酸钠和/或利福平50—60片(0.5克/片),共制成120丸,每丸约9克。
上述组合物中还可加如下原料药物:
桔梗10—15克 丹参10—20克 地骨皮10—15克
本发明肺结核丸的制备方法为:
1.捡净药内的泥砂、杂物等,用粗筛筛去泥土及杂物等粉末;
2.按上述配比先粗粉碎,再磨成细粉,搅拌均匀;
3.用紫外线照射消毒细粉;
4.将蜂蜜加热过滤,再用铜锅煎熬,去净蜡沫,熬至滴液成珠;
5.将上述药粉与蜂蜜搅拌均匀,制成每丸约九克的园球状,再用紫外线消毒过的纸和蜡壳包装后,用蜡密封。
临床资料表明,肺结核丸治疗肺结核的治愈率高达86.78%,总有效率为95.87%。具体情况如下:
患者:男1429人,女1406人,共2835人,年龄:10岁以下94例,11—20岁235例,21—30岁1265例,31—40岁68例,41—50岁235例,51—60岁209例,60岁以上116例;病程:6个月以下者1699例,6—12个月有1775例,12个月以上561例;分型:原发型肺结核680例,血型播散型420例,浸润型1429例,慢性纤维空调型235例,结核性胸膜炎71例。
服法:每日子、午、卯、酉四时各服1丸,小儿酌减。
疗程:4—6个月
治疗标准:
1.治愈:痰菌连续阴性(或连续阴转),病变吸收或无活动性;空洞
闭合均达半年以上者;如有空洞,则需痰菌连续阴转一年
以上者;全身症状消失。
2.显效:全身症状明显改善;痰菌连续阴转,病变明显吸收或吸收;
空洞闭合或缩小,均达三个月以上者。
3.有效:全身症状改善;痰菌阴转,病变明显吸收、吸收或无改变,
空洞闭合,缩小或无改变,均达一个月以上者;痰菌连续
阴性,病变吸收,空洞缩小,均达一个月以上者。
4.无效:全身症状、痰菌、X红均无改变。
治疗结果:
本组2835例病人中,临床治愈2461例,占86.78%;显效209例,占7.44%;有效48例,占1.65%;无效117例,占4.13%,总有效率达95.87%。2835例肺结核病例疗效统计
治愈 | 显效 | 有效 | 无效 | 合计 |
246186.78 | 2097.44 | 481.65 | 1174.13 | 2835100% |
病例一:
张××,男,29岁,汾西矿务局柳湾矿工人。患慢性纤维空洞型肺结核7年,中西医治疗,时轻时重。85年10月就诊时,见形体瘦弱,面色白,低热,盗汗,胸闷气促,咳嗽无力,痰多,清稀,痰中带血,有时咯血不止,纳呆腹胀。舌质淡、胖嫩,边有齿痕,苔白腻,脉沉细无力。
辩证:阴伤气耗,肺脾同病,致使肺失清肃,脾失健运,为肺痨后期之病变。肺气虚,故咳嗽无力,气短声低;气不化津,而成痰疾,则见痰清稀而量多;气虚不能固卫,故身热,自汗。其则一派气不摄血,脾不健运的见证。
诊断:肺痨(气阴两虚)
治法:滋阴润肺,益气健脾
方药:肺结核丸
服法:每日子、午、卯、酉四时各服1丸,温开水送下,服药期间忌服生葱、生蒜、烟酒。
调护:注意卧床休息,调节营养。
辅助检查:血红蛋白8.5克,血沉52mm/H,痰涂(+);X线拍片见:慢性纤维空洞型肺结核进展期。
治疗结果:入院后服肺结核丸,服法同前。经两个月治疗,饮食增加,精神好转,咯血停止,偶尔咳嗽,痰量减少。X线透视见病灶有所吸收。四个月后,全身症状明显改善,痰菌阴转。共住院治疗六个月,全身症状消失,空洞闭合,痰菌连续四个月阴转。97年5月下井采煤,至今随访未复发。
病例二:
王××,男,33岁,灵石县委干部。患浸润型肺结核一年半,咳嗽,咳血,胸痛,短气加剧二月,于82年2月就诊。症见形体消瘦,面色黧黑,咳嗽剧烈,痰中带血,声音嘶哑,胸痛短气,发热汗出,纳差,舌质紫暗,脉细涩。
辩证:病久血淤,肺脉阻滞,失却肃降功能,故咳嗽剧烈而痰中带血,淤血不行,营虚卫热,则发热汗出,胸阳不振,则胸痛而短气,舌质紫暗,脉细涩,为血脉淤阻之征。
诊断:肺痨(气血淤滞型)
治则:润肺化痰,祛淤通络。
方药:肺结核丸
服法:从早晨六时起,每隔六小时服一丸,温开水送下。服药期忌服生葱、生蒜、长期禁烟酒。
调护:增加营养,卧床休息
辅助检查:血红蛋白8克%,血沉48mm/H,淡涂(+),X线片所见:右肺浸润型肺结核(进展期)。
治疗结果:注院后治疗一个月,咳嗽胸痛明显减轻,痰涂阴转,三月后诸症消失,经化验检查,血红蛋白13克%,血沉2mm/H,痰涂连续阴转。X片示:右肺散在多数个小点状硬结钙化阴影,两肺纹理较粗糙,92年2月随访至今未复发。
临床资料表明,本发明肺结核丸的效果是显而易的:
1.治愈率高达86.78%,总有效率95.87%。
2.愈后随访表明,愈后不复发。
3.对患者随访表明肺结核丸无毒副作用,无抗药性。
4.对不同年龄的患者,不同类型的肺结核皆有显效。
Claims (2)
1.一种肺结核丸药,其特征在于原料药物组成如下:砂仁9—10克,麻黄25—30克,紫苑20—40克,甘草10—15克,当归15—20克,黄芪20克,枇杷叶20—30克,金银花15—20克,建曲15—20克,山楂18—20克,川贝母10克,白芨15—20克,百部15克,麦冬18—20克,白芥子25—30克,五味子20克,雷米封、对胺基水杨酸钠和/或每片20.5克的利福平60—60片。
2.如权利要求1所述的肺结核丸的制法,其特征在于:
(1)检净药内的泥砂、杂物等,用粗筛筛去泥土及杂物等粉末;
(2)按上述配比先粗粉碎,再磨成细粉,搅拌均匀;
(3)用紫外线照射消毒细粉;
(4)将蜂蜜加热过滤,再用铜锅煎熬,去净蜡沫,熬至滴液成珠;
(5)将上述药粉与蜂蜜搅拌均匀,制成每丸约九克的园球状,再用紫外线消毒过的纸和蜡壳包装后,用蜡密封。
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CN1106290A (zh) * | 1994-02-02 | 1995-08-09 | 刘玉正 | 中药结核康及其制造方法 |
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中医杂志1993,34(8) 1993.8.31 王学瑞,中药治疗药物流产后出血的疗效观察 * |
安徽中医学院学报1994,13(1) 1994.1.31 张翠萍,固冲清宫汤治疗药物流产后出血过多48例 * |
安徽中医学院学报1994,13(1) 1994.1.31 张翠萍,固冲清宫汤治疗药物流产后出血过多48例;中医杂志1993,34(8) 1993.8.31 王学瑞,中药治疗药物流产后出血的疗效观察 * |
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