CN105999118A - Traditional Chinese medicinal composition for treating chloasma - Google Patents
Traditional Chinese medicinal composition for treating chloasma Download PDFInfo
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Abstract
The invention discloses a traditional Chinese medicinal composition for treating chloasma. The traditional Chinese medicinal composition is prepared from the following traditional Chinese medicinal raw materials in parts by weight: 10 to 30 parts of stellaria yunnanensis, 10 to 20 parts of herb of cupleaf passionflower, 10 to 20 parts of rhizoma polygonati odorati, 5 to 15 parts of radix angelicae dahurioae, 10 to 20 parts of bark or root of pendulous euonymus, 10 to 20 parts of semen coicis, 10 to 20 parts of Chinese trumpetcreeper flower, 5 to 15 parts of herba selaginellae, 10 to 20 parts of herba menthae, 10 to 20 parts of root of himalayan prinsepia, 5 to 15 parts of rhizoma atractylodis, 10 to 20 parts of semen oroxyli, 10 to 20 parts of semen cuscutae, 10 to 20 parts of radix lithospermi, 5 to 15 parts of folium isatidis, 10 to 20 parts of herba ecliptae, 5 to 15 parts of rose, 10 to 20 parts of longan, 10 to 20 parts of cortex dictamni, 5 to 15 parts of radix curcumae, 10 to 20 parts of motherwort herb, 10 to 20 parts of lightyellow sophora root and 5 to 15 parts of liquorice root. The traditional Chinese medicinal composition disclosed by the invention has the efficacies of clearing away heat and toxic materials, promoting blood circulation to remove blood stasis, soothing the liver and relieving depression and cooling blood and removing ecchymosis, is remarkable in curative effect of treating the chloasma, and is safe and reliable.
Description
Technical field
The present invention relates to the medicinal preparation not determining structure of a kind of traditional herbal medicines, a kind of Chinese medicine composition treating chloasma.
Background technology
Chloasma is also referred to as chloasma hepaticum, and for the yellowish-brown pigmentation of face, many symmetrical butterflies are distributed in buccal.Being more common in women, in its blood, estrogen level height is main cause, falls ill relevant with gestation, Long-term Oral contraceptive, menoxenia.The most often show themselves in that yellowish-brown or dark brown patch, be often symmetrically distributed in cheekbone buccal, it is possible to involving socket of the eye week, forehead, upper lip and nose, edge is the most more apparent.Without subjective symptom and general malaise.Psychentonia, stays up late, and fatigue can increase the weight of skin lesion.At present, clinical treatment chloasma is usually taken the medicines such as external tyrosinase inhibitor ointment, though tool certain curative effect, but need life-time service, it is easily generated dependency, and cures the symptoms, not the disease.
Chloasma, traditional Chinese medical science primary disease is called " miscellaneous diseases on face ", " chloasma ", " dusty face ", " butterfly spot " etc..Its mechanism is evil criminal's skin, disharmony between QI and blood, stagnation of QI due to depression of the liver, caused by energy stagnation and blood stasis.
According to theory of Chinese medical science, for the pathogeny of chloasma, with dispersing the stagnated live-QI to relieve the stagnation of QI, blood circulation promoting and blood stasis dispelling as the rule for the treatment of, carry out dialectical composition of prescription, to reach the purpose for the treatment of both the principal and secondary aspects of a disease.
Summary of the invention
Prior art uses the Drug therapy chloasma such as tyrosinase inhibitor ointment there is the deficiency that drug dependence is strong, cure the symptoms, not the disease to overcome, the present invention provide a kind of prepare conveniently, evident in efficacy, safe and reliable, the Chinese medicine composition for the treatment of chloasma that has no side effect.
nullThe technical solution adopted for the present invention to solve the technical problems is: a kind of Chinese medicine composition treating chloasma，It is characterized in that: its raw material of Chinese medicine and weight be: Radix Stellariae Yunnanensis 10-30 part，Herba Passiflorae Cupiformis 10-20 part，Rhizoma Polygonati Odorati 10-20 part，Radix Angelicae Dahuricae 5-15 part，Cortex seu Radix Euonymi oxyphyllae 10-20 part，Semen Coicis 10-20 part，Flos Campsis 10-20 part，Cortex Phellodendri 5-15 part，Herba Menthae 10-20 part，Radix prinsepiae utilis 10-20 part，Rhizoma Atractylodis 5-15 part，Semen Oroxyli 10-20 part，Semen Cuscutae 10-20 part，Radix Arnebiae (Radix Lithospermi) 10-20 part，Folium Isatidis 5-15 part，Herba Ecliptae 10-20 part，Flos Rosae Rugosae 5-15 part，Arillus Longan 10-20 part，Cortex Dictamni 10-20 part，Radix Curcumae 5-15 part，Herba Leonuri 10-20 part，Radix Sophorae Flavescentis 10-20 part，Radix Glycyrrhizae 5-15 part.
The preferred technical solution of the present invention is: a kind of Chinese medicine composition treating chloasma, it is characterized in that: its raw material of Chinese medicine and weight be: Radix Stellariae Yunnanensis 20 parts, Herba Passiflorae Cupiformis 15 parts, Rhizoma Polygonati Odorati 15 parts, the Radix Angelicae Dahuricae 10 parts, Cortex seu Radix Euonymi oxyphyllae 15 parts, Semen Coicis 15 parts, Flos Campsis 15 parts, Cortex Phellodendri 10 parts, Herba Menthae 15 parts, Radix prinsepiae utilis 15 parts, Rhizoma Atractylodis 10 parts, Semen Oroxyli 15 parts, Semen Cuscutae 15 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Folium Isatidis 10 parts, Herba Ecliptae 15 parts, Flos Rosae Rugosae 10 parts, Arillus Longan 15 parts, Cortex Dictamni 15 parts, Radix Curcumae 10 parts, Herba Leonuri 15 parts, Radix Sophorae Flavescentis 15 parts, 10 parts of Radix Glycyrrhizae.
Chinese medicine composition of the present invention is under Traditional Chinese medical theory and clinical experience instruct, selected medicament composing prescription.In Chinese medicine composition of the present invention: Radix Stellariae Yunnanensis has effect of strengthening spleen and nourishing blood, the liver and the kidney tonifying, detumescence；Herba Passiflorae Cupiformis has effect of expelling wind and removing dampness, promoting blood circulation and stopping pain, tranquilizing by nourishing the heart；Rhizoma Polygonati Odorati has effect of nourishing YIN to relieve dryness, promoting the production of body fluid to quench thirst；The Radix Angelicae Dahuricae has relieving exterior syndrome and dispelling cold, expelling pathogenic wind and restoring the functions of orifices in face, promoting blood circulation and stopping pain, dampness leukorrhagia stopping, effect of detumescence and apocenosis；Cortex seu Radix Euonymi oxyphyllae has effect of expelling wind and removing dampness, promoting blood circulation to restore menstrual flow, promoting diuresis to remove toxic substance；Semen Coicis has inducing diuresis to remove edema, spleen invigorating is dried, effect of arthralgia relieving by relaxing muscles and tendons, clearing away heat and discharging pus；Flos Campsis has effect of clearing away heat and cooling blood, blood stasis-eliminating and stagnation-dissipating, dispelling wind for relieving itching；Cortex Phellodendri has heat clearing and damp drying, pathogenic fire purging except steaming, effect of detoxification sore treatment；Herba Menthae has dispelling wind and heat pathogens, clear profit removing toxic substances, effect of dispersing the stagnated live-QI to relieve the stagnation of QI；Radix prinsepiae utilis has astringes the lung, only void cough, effect of chronic cough；Rhizoma Atractylodis have drying damp and strengthening spleen, effect of expelling wind and cold；Semen Oroxyli has effect of removing heat from the lung and relieving sorethroat, dispersing the stagnated liver-QI for regulating the stomach；Semen Cuscutae has the kidney invigorating and essence nourishing, effect of nourishing the liver spleen invigorating；Radix Arnebiae (Radix Lithospermi) has clearing away heat and cooling blood, blood circulation promoting and blood stasis dispelling, effect of removing toxic substances rash；Folium Isatidis has effect of heat-clearing and toxic substances removing, blood cooling and ecchymoses removing；Herba Ecliptae has effect of nourishing the liver and kidney, cooling blood for hemostasis；Flos Rosae Rugosae has effect of promoting QI circulation for relieving depression, promoting blood flow to regulate menstruation；Arillus Longan has benefiting QI and nourishing blood, the strengthening the spleen that whets the appetite, the effect of Fructus Alpiniae Oxyphyllae of calming the nerves；Cortex Dictamni has heat clearing and damp drying, the effect of removing toxic substances of dispeling the wind；Radix Curcumae has effect of regulating qi to disperse stagnation, heart fire-clearing upset-relieving；Herba Leonuri has effect of promoting blood flow to regulate menstruation, inducing diuresis to remove edema, heat-clearing and toxic substances removing；Radix Sophorae Flavescentis has effect of heat clearing and damp drying, wind dispelling insecticide；Radix Glycyrrhizae has effect of invigorating the spleen and replenishing QI, heat-clearing and toxic substances removing, expelling phlegm for arresting cough, coordinating the actions of various ingredients in a prescription.Drug component in the present composition, through dialectical compatibility, complements each other using, and has synergism, plays effect of heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, dispersing the stagnated live-QI to relieve the stagnation of QI, blood cooling and ecchymoses removing altogether, and chloasma reaches the purpose for the treatment of both the principal and secondary aspects of a disease.
The component of the present composition all uses natural raw material of Chinese medicine, and its preparation is easy, medicine source is wide, low cost.It follows the prescriptions principle of the traditional Chinese medical science, and various component drug use the use that is decocted in water for oral dose.By clinic application checking and middle adverse drug reaction (ADR) safety evaluatio, it is evident in efficacy, safe and reliable, mild in medicine property and, toxic and side effects does not occurs, total effective rate 92%, cure rate reaches 73%.
Detailed description of the invention
Below in conjunction with embodiment, the present invention will be further described.
Embodiment
1
A kind of Chinese medicine composition treating chloasma, its raw material of Chinese medicine and weight proportion be: Radix Stellariae Yunnanensis 20g, Herba Passiflorae Cupiformis 15g, Rhizoma Polygonati Odorati 15g, Radix Angelicae Dahuricae 10g, Cortex seu Radix Euonymi oxyphyllae 15g, Semen Coicis 15g, Flos Campsis 15g, Cortex Phellodendri 10g, Herba Menthae 15g, Radix prinsepiae utilis 15g, Rhizoma Atractylodis 10g, Semen Oroxyli 15g, Semen Cuscutae 15g, Radix Arnebiae (Radix Lithospermi) 15g, Folium Isatidis 10g, Herba Ecliptae 15g, Flos Rosae Rugosae 10g, Arillus Longan 15g, Cortex Dictamni 15g, Radix Curcumae 10g, Herba Leonuri 15g, Radix Sophorae Flavescentis 15g, Radix Glycyrrhizae 10g.
Embodiment
2
A kind of Chinese medicine composition treating chloasma, its raw material of Chinese medicine and weight proportion be: Radix Stellariae Yunnanensis 30g, Herba Passiflorae Cupiformis 10g, Rhizoma Polygonati Odorati 20g, Radix Angelicae Dahuricae 5g, Cortex seu Radix Euonymi oxyphyllae 20g, Semen Coicis 10g, Flos Campsis 20g, Cortex Phellodendri 5g, Herba Menthae 20g, Radix prinsepiae utilis 10g, Rhizoma Atractylodis 15g, Semen Oroxyli 10g, Semen Cuscutae 20g, Radix Arnebiae (Radix Lithospermi) 10g, Folium Isatidis 15g, Herba Ecliptae 10g, Flos Rosae Rugosae 15g, Arillus Longan 10g, Cortex Dictamni 20g, Radix Curcumae 5g, Herba Leonuri 20g, Radix Sophorae Flavescentis 10g, Radix Glycyrrhizae 15g.
Embodiment
3
A kind of Chinese medicine composition treating chloasma, its raw material of Chinese medicine and weight proportion be: Radix Stellariae Yunnanensis 10g, Herba Passiflorae Cupiformis 20g, Rhizoma Polygonati Odorati 10g, Radix Angelicae Dahuricae 15g, Cortex seu Radix Euonymi oxyphyllae 10g, Semen Coicis 20g, Flos Campsis 10g, Cortex Phellodendri 15g, Herba Menthae 10g, Radix prinsepiae utilis 20g, Rhizoma Atractylodis 5g, Semen Oroxyli 20g, Semen Cuscutae 10g, Radix Arnebiae (Radix Lithospermi) 20g, Folium Isatidis 5g, Herba Ecliptae 20g, Flos Rosae Rugosae 5g, Arillus Longan 20g, Cortex Dictamni 10g, Radix Curcumae 15g, Herba Leonuri 10g, Radix Sophorae Flavescentis 20g, Radix Glycyrrhizae 5g.
Embodiment
4
A kind of Chinese medicine composition treating chloasma, its raw material of Chinese medicine and weight proportion be: Radix Stellariae Yunnanensis 23g, Herba Passiflorae Cupiformis 12g, Rhizoma Polygonati Odorati 17g, Radix Angelicae Dahuricae 7g, Cortex seu Radix Euonymi oxyphyllae 18g, Semen Coicis 12g, Flos Campsis 17g, Cortex Phellodendri 7g, Herba Menthae 18g, Radix prinsepiae utilis 12g, Rhizoma Atractylodis 13g, Semen Oroxyli 12g, Semen Cuscutae 18g, Radix Arnebiae (Radix Lithospermi) 12g, Folium Isatidis 13g, Herba Ecliptae 12g, Flos Rosae Rugosae 13g, Arillus Longan 12g, Cortex Dictamni 18g, Radix Curcumae 7g, Herba Leonuri 18g, Radix Sophorae Flavescentis 12g, Radix Glycyrrhizae 13g.
Embodiment
5
A kind of Chinese medicine composition treating chloasma, its raw material of Chinese medicine and weight proportion be: Radix Stellariae Yunnanensis 17g, Herba Passiflorae Cupiformis 18g, Rhizoma Polygonati Odorati 12g, Radix Angelicae Dahuricae 13g, Cortex seu Radix Euonymi oxyphyllae 12g, Semen Coicis 18g, Flos Campsis 12g, Cortex Phellodendri 13g, Herba Menthae 12g, Radix prinsepiae utilis 18g, Rhizoma Atractylodis 7g, Semen Oroxyli 18g, Semen Cuscutae 12g, Radix Arnebiae (Radix Lithospermi) 17g, Folium Isatidis 7g, Herba Ecliptae 18g, Flos Rosae Rugosae 7g, Arillus Longan 18g, Cortex Dictamni 12g, Radix Curcumae 13g, Herba Leonuri 12g, Radix Sophorae Flavescentis 18g, Radix Glycyrrhizae 7g.
Chinese medicine composition in embodiment of the present invention decocting method routinely produces medicament.Concrete grammar is as follows: put in container by the raw material of Chinese medicine of prescription, adds cold water and covers powder, soak 15～20 minutes, added water no powder about 8 centimetres, carries out decocting for the first time, at a simmer before use intense fire to decoct, with slow fire boiling 20～30 minutes after boiling；Second time decocts, and added water no powder about 6 centimetres, decocts 15～20 minutes after water boiling.Twice decoction is removed slag extracting juice, merges.
The present invention, with a kind of Chinese medicine composition treating chloasma given by embodiment 1, does clinical efficacy and is summarized as follows:
One, general data: Chinese medicine composition of the present invention is applied to clinical observation case female 64 example, age 20～65 years old.
Two, diagnostic criteria:
1, face skin lesion is black speck, puts down in skin, color such as dust and dirt, light brown or light black, without pain of itching；
2, often occur at facial areas such as volume, eyebrow, cheek, bridge of the nose, lips；
3, being more common in woman, onset has chronic process；
4, hyperpigmentation during tissue pathology checking shows epidermis, also has more pigment addicted to melanocyte in corium；Minority lymphocytic infiltration can be had at blood vessel and perifollicolar.
Three, usage and dosage: during clinical practice, one day potion, decocting twice extracting juice about 400ml, point early, late twice warm is taken, and within six days, is a course for the treatment of.Take medicine period avoid eating anything raw or cold, pungent thing.
Four, criterion of therapeutical effect:
1, cure: facial skin is normal skin tone；
2, take a turn for the better: skin lesion disappears more than 30%；
3, do not heal: skin lesion is without significant change, or disappears less than 30%.
Five, therapeutic effect: in this clinical observation case, take medicine 5-10 the course for the treatment of, cure 47 examples, take a turn for the better 12 examples, the most 5 examples.During treatment centering clinical drug cause all types of anaphylaxis, cause suspected of medicine in terms of each system of human body, organ, the function of tissue and form abnormal, cause the mutagenesis reactions such as cancer, the dependency of medicine suspected of medicine and think that other untoward reaction important or valuable are evaluated, in i.e., adverse drug reaction (ADR) is evaluated, and untoward reaction and toxic and side effects do not occur.
Six, model case:
Case 1: Lu, female, 32 years old.Patient's readme: filbert little speckle, painless gargalesthesia occurs in period of gestation face.Gestation uses inhibitor ointment to smear after terminating, and effect is also and inconspicuous.After 4 courses for the treatment of of medicament taking prepared by Chinese medicine composition of the present invention, conscious speckle substantially disappears, of pink and healthy-looking；Continue to take 3 courses for the treatment of, transference cure, cure.
Case 2: grandson, female, 54 years old.Patient's readme: suffer from chloasma for many years, from the beginning of time cover with speckle filbert, irregular at bilateral cheek, become apparent from after Exposure to Sunlight in summer.The most over the past half year, skin lesion is more and more serious, and speckle only increases.Taking 4 courses for the treatment of of medicament prepared by Chinese medicine composition of the present invention, brown patch is substantially desalinated, and skin lesion disappears many；Continuing after taking 6 courses for the treatment of, facial skin is normal skin tone, cures.
Claims (2)
1. the Chinese medicine composition treating chloasma, it is characterized in that: its raw material of Chinese medicine and weight be: Radix Stellariae Yunnanensis 10-30 part, Herba Passiflorae Cupiformis 10-20 part, Rhizoma Polygonati Odorati 10-20 part, Radix Angelicae Dahuricae 5-15 part, Cortex seu Radix Euonymi oxyphyllae 10-20 part, Semen Coicis 10-20 part, Flos Campsis 10-20 part, Cortex Phellodendri 5-15 part, Herba Menthae 10-20 part, Radix prinsepiae utilis 10-20 part, Rhizoma Atractylodis 5-15 part, Semen Oroxyli 10-20 part, Semen Cuscutae 10-20 part, Radix Arnebiae (Radix Lithospermi) 10-20 part, Folium Isatidis 5-15 part, Herba Ecliptae 10-20 part, Flos Rosae Rugosae 5-15 part, Arillus Longan 10-20 part, Cortex Dictamni 10-20 part, Radix Curcumae 5-15 part, Herba Leonuri 10-20 part, Radix Sophorae Flavescentis 10-20 part, Radix Glycyrrhizae 5-15 part.
A kind of Chinese medicine composition treating chloasma the most according to claim 1, it is characterized in that: its raw material of Chinese medicine and weight be: Radix Stellariae Yunnanensis 20 parts, Herba Passiflorae Cupiformis 15 parts, Rhizoma Polygonati Odorati 15 parts, the Radix Angelicae Dahuricae 10 parts, Cortex seu Radix Euonymi oxyphyllae 15 parts, Semen Coicis 15 parts, Flos Campsis 15 parts, Cortex Phellodendri 10 parts, Herba Menthae 15 parts, Radix prinsepiae utilis 15 parts, Rhizoma Atractylodis 10 parts, Semen Oroxyli 15 parts, Semen Cuscutae 15 parts, Radix Arnebiae (Radix Lithospermi) 15 parts, Folium Isatidis 10 parts, Herba Ecliptae 15 parts, Flos Rosae Rugosae 10 parts, Arillus Longan 15 parts, Cortex Dictamni 15 parts, Radix Curcumae 10 parts, Herba Leonuri 15 parts, Radix Sophorae Flavescentis 15 parts, 10 parts of Radix Glycyrrhizae.
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