CN105998667A - Medicine for treating hypotension and preparation method thereof - Google Patents

Medicine for treating hypotension and preparation method thereof Download PDF

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CN105998667A
CN105998667A CN201610621536.4A CN201610621536A CN105998667A CN 105998667 A CN105998667 A CN 105998667A CN 201610621536 A CN201610621536 A CN 201610621536A CN 105998667 A CN105998667 A CN 105998667A
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李志玉
李爱花
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Abstract

The invention discloses a medicine for treating hypotension and a preparation method thereof, and belongs to the field of traditional Chinese medicines. The effective ingredient of the traditional Chinese medicine is prepared from the following raw materials: ventilago leiocarpa benth, grapes, angelica sinensis, eclipta, textile screw pine seeds, licorice roots, longan pulp, radix rehmanniae praeparata, poria cocos, Chinese dates, stephanotis chunii, lucid ganoderma, asiatic bilberry leaves, radix polygonati officinalis, cortex acanthopanacis and odontobutis obscura. The traditional Chinese medicine is prepared from compatible and complementary medicinal materials, has the effects of strengthening tendons and bones, promoting blood vessels, tonifying liver and kidneys, nourishing yin and moistening lung, nourishing stomach and promoting generation of body fluids, strengthening spleen and homogenizing stomach, calming heart and tranquilizing and the like, can directly reach the disease part by the combination effect of the medicinal materials, has the advantages of quick response, high cure rate, no toxic or side effect and the like on treatment of dizziness, headache, inappetence, fatigue, pale face, dyspepsia, cold limbs, palpitation, dyspnea and other symptoms, is low in price and easy to prepare, and is worthy of clinical wide popularization and application.

Description

One is used for treating hypotensive medicine and preparation method
Art
The present invention relates to the field of Chinese medicines, particularly relate to a kind of for treating hypotensive medicine and preparation method.
Background technology
Hypotension refers to the subnormal state of systemic arterial pressure power.The most usually cause due to hypertension the heart, The infringement of the important organ such as brain, kidney and attention, World Health Organization's also diagnostic criteria to hypertension has clear stipulaties, but Hypotensive diagnosis there is no unified standard.It is generally acknowledged that adult's artery of upper extremity blood pressure is less than 12/8kPa (90/60mmHg) Hypotension.Physiological and pathologic hypotension can be divided into according to the cause of disease, acute and chronic hypotension can be divided into according to onset form.
Acute hypotension refers to that patients' blood is decreased obviously suddenly by normal or higher level, clinically often because of brain, There is the symptom such as dizziness, pupil, limb soft, cold sweat, cardiopalmus, oliguria in the important organ ischemia such as the heart, kidney, severe patient show as fainting or Shock.Chronic hypotension refers to that blood pressure is consistently less than the state of normal range.Constitutional hypotension is more common in the women in 20-50 year And old people, the lighter can be without any symptom, and neurolysis, dizziness, headache occurs in severe one, even faints.When summer temperature is higher Become apparent from.It is 3 minutes of orthostatism in that postural hypotension is defined as changing position, shrinks drops > 20mmHg or diastole Drops > 10mmHg, simultaneously with the symptom of Low perfusion, these symptoms include: giddy, dizziness, blurred vision, weak, nauseating, Cognitive function disorder, cardiopalmus, neck back pain.Treatment of older patient with isolated systolic, with diabetes, Hypovolemia, applies diuresis Agent, expansion blood vessel medicine or antipsychotics person are susceptible to postural hypotension.
Often be it is believed that healthy nothing serious hypotension state, the major diseases such as heart and brain infraction can be caused equally；Low Blood pressure is also easily caused vision, auditory dysesthesia, induces or increase the weight of alzheimer disease, dizzy, faint, fall, incidence of fracture significantly Increase；Weak, neurolysis, the situation such as depressed, melancholy often occur, and affect quality of life.
At present, if treating hypotensive drug main based on hormone, as 9-a fludrocortisone, caffeine, ephedrine and Salt Sour's etc., it is relatively big to there is side effect in this type of medicine, and therapeutic effect is the best, the most repeatedly falls ill, the high deficiency for the treatment of cost.For This, we are badly in need of developing a kind of medicine to help patient to break away from the misery that hypotension is brought.
Summary of the invention
The invention provides a kind of for treating hypotensive medicine and preparation method；Compatibility of drugs of the present invention is suitable, phase Benefit evident, there is the effects such as bone and muscle strengthening, arteries and veins of invigorating blood circulation, liver and kidney tonifying, nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming, All medicines drug effect that is harmonious can be gone directly diseased region, and the dizziness that causes for treatment hypotension, headache, inappetence, fatigue, face are grey In vain, the symptom such as dyspepsia, four cold extremities, cardiopalmus, dyspnea has instant effect, cure rate is high, have no side effect, safe ready Etc. advantage, and low price, easily prepare, wide popularization and application on clinic.
For achieving the above object, technical scheme is implemented as follows:
One is used for treating hypotensive medicine, make described effective ingredient raw material composition and parts by weight be:
Make described effective ingredient raw material composition and parts by weight be:
Make described effective ingredient raw material composition and parts by weight be:
Make described effective ingredient raw material composition and parts by weight be:
A kind of preparation method for treating hypotensive medicine, comprises the following steps that:
(1) Radix seu Caulis Verntilaginis Leiocarpae, Fructus Pandani tectorii and Cortex Acanthopancis are immersed yellow wine 3-4 hour, after taking-up, sun dehydration, pour in pot, literary composition Fire parch, after cooling, smashs to pieces and grinds into powder, obtained the fine powder of 120 mesh, standby；
(2) add the water of 8 times amount after Fructus Vitis viniferae, Herba Ecliptae, Folium Vaccinii Bracteati and Rhizoma Polygonati Odorati being mixed, extract 2-3 hour, filter, take Medicinal liquid；In remaining residue, add the water of 6 times amount, extract 1-2 hour, filter, taking liquid；Merge twice medicinal liquid, concentrate The thick paste of relative density 1.10-1.15 at becoming 60 DEG C, drying under reduced pressure, standby；
(3) yellow wine uniform spraying will be used after Chinese angelica slicing, the most vexed, fry with low baking temperature in putting pot, take out, cool, grind into powder, obtain Cross the fine powder of 160, standby；
(4) add cooked Mel after being cut into slices by Radix Glycyrrhizae a little with boiled water, mix thoroughly, the most vexed, fry to becoming with slow fire in putting pot Buff, tack-free for degree, taking-up cools, and grinds into powder, obtains the fine powder of 180 mesh, standby；
(5) Arillus Longan, Radix Rehmanniae Preparata, Poria, Fructus Jujubae, Stephanotis chunii Tsiang, Ganoderma and Odontobutis obscura (T. Et S.) are put in container, be firstly added 10- 15 times amount distilled water immersions are after 4-5 hour, heated and boiled 3-4 hour, extract；Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extract；Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts；United extraction liquid, filters, obtains filtrate Standby；
(6) fine powder, thick paste and the filtrate mixing that step (1)-step (5) prepares, makes tablet, is described for controlling Treat hypotensive medicine.
The property of medicine of Chinese medicine used by the present invention is as follows:
Radix seu Caulis Verntilaginis Leiocarpae: sweet in the mouth, warm in nature；Return lung, spleen channel.Filling blood, bone and muscle strengthening, relax meridians.Main deficient qi and blood, has through uncomfortable, Blood deficiency amenorrhea, rheumatalgia, traumatic injury, lumbar muscle strain." Guangxi Chinese herbal medicine " carries: " blood of dispelling dispels the wind, strong muscles and bones.Eliminate-poverty blood, Rheumatic arthritis, lumbar muscle strain.”
Fructus Vitis viniferae: sweet in the mouth, acid, property is put down；Return lung, spleen, kidney channel.Fill blood, bone and muscle strengthening, diuresis.Main deficient qi and blood, the deficiency of the lung is coughed Coughing, palpitation and night sweat, excessive thirst, rheumatic arthralgia, gonorrhea, pneumonedema, varioliform exanthema is impermeable." Luchuan book on Chinese herbal medicine " carries: " nourish strong, enrich blood, heart tonifying Diuresis.Control lumbago, gastropathy, neurolysis, blood deficiency heart beating.”
Radix Angelicae Sinensis: sweet in the mouth, pungent, bitter, warm in nature；Return liver, the heart, spleen channel.Enrich blood, invigorate blood circulation, menstruction regulating and pain relieving, moisturize laxation.Main blood deficiency All cards, menoxenia, amenorrhea, dysmenorrhea, lump in the abdomen knot is poly-, and metrorrhagia, asthenia cold abdominalgia, flaccidity syndrome and arthralgia syndrome, numbness of the skin, dryness of the intestine dyschezia, after bloody dysentery Weight, ulcer sores, injury from falling down." Treatise on Febrile Disease with Notes " carries: " arteries and veins person's house of blood, all blood all belongs to the heart, and all persons of promoting blood circulation must first reinforcing the heart benefit Blood, therefore Zhang Zhongjing is controlled brothers and is fainted cold, thready pulse being about to disappear person, by the hardship temperature of Radix Angelicae Sinensis to help painstaking effort." modern medicine study confirmation, Radix Angelicae Sinensis Infusion quite can significant promotion hemoglobin and erythrocytic generation to mice.
Herba Ecliptae: sweet in the mouth, acid, cool in nature；Return liver, kidney channel.Liver and kidney tonifying, cooling blood for hemostasis.Main deficiency of the liver and kindey, has a dizzy spell, Early whitening of beard and hair, spits blood, spitting of blood, and epistaxis is had blood in stool, dysentery, metrorrhagia, traumatic hemorrhage." detailed outline " carries: " crow beard and hair, kidney tonifying is cloudy." modern Medical research confirms, application guinea pig isolated heart observes that Herba Ecliptae has increase coronary flow effect, and makes ECG T wave change Improved.
Fructus Pandani tectorii: acrid in the mouth, light, cool in nature；Return kidney,spleen,liver, stomach warp.Spleen reinforcing benefit blood, promoting the circulation of QI to relieve pain, reduce phlegm dampness removing, improving eyesight. Main dysentery, stomachache, cough, hernia, orchitis, hemorrhoid, dysuria, the raw cataracta of mesh." detailed outline is picked up any lost article from the road " carries: " tonifying the spleen and stomach, primordial QI reinforcing Gas, subdues high sun, helps the soil that declines, strong spirit, benefit blood, wide painful abdominal mass, expectorant, alcoholic intoxication, only sends out thirsty after drinking, the profit head, happily benefit Will.”
Radix Glycyrrhizae: sweet in the mouth, property is put down；Return spleen, stomach, the heart, lung meridian.QI invigorating invigorating middle warmer, relieving spasm to stop pain, nourishing the lung to arrest cough, eliminating fire and detoxication, adjust With all medicines.Main asthenia lack of appetite, leanness yellowish complexion, shortness of breath and palpitation, loose stool of suffering from abdominal pain, extremity contraction urgency pain, hysteria, cough and asthma, throat Swelling and ache, ulcerative carbuncle swells and ache, infantile carbuncle, and medicine, alimentary toxicosis." not Lu " carries: " warming the middle warmer and descending qi, stuffy sensation with restlessness is losed heart, and hinders dirty cough, Quench the thirst, qualcomm meridian, profit vim and vigour, solve hundred poison of drug.”
Arillus Longan: sweet in the mouth, warm in nature；GUIXIN, kidney,liver,spleen warp.Reinforcing the heart spleen, replenishing QI and blood, tranquilizing mind.Main deficiency of both the heart and spleen, QI and blood Palpitation with fear caused by deficiency, palpitation with a distress feeling, insomnia, forgetful, blood deficiency and yellow complexion, have through uncomfortable, metrorrhagia." the southern regions of the Yunnan Province book on Chinese herbal medicine " carries: " nourishing blood to tranquillize the mind, Long intelligence arresting sweating, whet the appetite strengthening the spleen.”
Radix Rehmanniae Preparata: sweet in the mouth, warm in nature；Return liver, kidney channel.Enriching blood moist, benefit essence fills out marrow.Main blood tiger is sallow, dizziness cardiopalmus, menstruation Uncomfortable, collapse more than, hepatic and renal YIN deficiency, hectic fever night sweat, sexual impotence of passing out semen, infertility, soreness of the waist and knees, Hiccough and deaf, the head is dim-sighted, palpus Send out the whitest, quench one's thirst, constipation, dyspnea with rapid and short breath of suffering from a deficiency of the kidney." detailed outline " carries: " filling out bone marrow, long muscle, promoting generation of vital essence and blood, tonifying five ZANG-organs, internal injury are not enough, logical blood Arteries and veins, profit knowledge, black beard and hair, man's five kinds of strain and seven kinds of impairment, woman's damaging the spleen and stomach threatened abortion, irregular menorrhea, tire produces all kinds of diseases and ailments.”
Poria: sweet in the mouth, light, property is put down；GUIXIN, spleen, lung, kidney channel.Eliminating dampness and diuresis, invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming.Main urine is not Profit, edema distension, phlegm retention cough with dyspnea, vomiting, insufficiency of the spleen lack of appetite, have loose bowels, palpitation and restlessness, insomnia forgetfulness, nebulousurine of passing out semen." medicine origin " Carry: " dehumidifying, blood between profit waist umbilicus, and middle QI invigorating are main.Control excessive yellow or red and unfavorable.”
Fructus Jujubae: sweet in the mouth, warm in nature；Return spleen, stomach warp.Tonifying the spleen and stomach, replenishing QI and blood, tranquilizing mind, adjust battalion to defend, and the property of medicine.Main taste are empty Weak, insufficiency of vital energy and blood, anorexia and loose stool, fatigue and weakness, palpitation and insomnia, woman hysteria, disharmony of nutrient QI with defensive QI." not Lu " carries: " invigorating the spleen and replenishing QI, Strongly, relieving restlessness is vexed, treats under the heart outstanding, and intestinal is out-of-the-way.”
Stephanotis chunii Tsiang: sweet in the mouth, pungent, warm in nature；Return liver, kidney channel.Enrich blood, invigorate blood circulation, stimulating milk secretion.Main menoxenia, dysmenorrhea, puerperal blood Void, hypogalactia." Xinhua's book on Chinese herbal medicine outline " carries: " root, leaf: for blood deficiency in puerperal, hypogalactia, dysmenorrhea and menoxenia.”
Ganoderma: sweet in the mouth, property is put down；Return lung, the heart, spleen, kidney channel.Replenishing QI and blood, tranquilizing mind, strengthening the spleen and stomach.Main asthenia, cardiopalmus, insomnia, Dizziness, spiritlessness and weakness, chronic cough asthma, coronary heart disease, silicosis, tumor.
Folium Vaccinii Bracteati: sour in the mouth, puckery, property is put down；GUIXIN, spleen, kidney channel.Benefit the intestines and stomach, nourishing the liver and kidney.Main deficiency of spleen-QI and stomach-QI, chronic diarrhea, few food, Deficiency of the liver and kindey, waist knee joint is weak, early whitening of beard and hair." book on Chinese herbal medicine converges and says " carries: " QI invigorating adds essence, removing heat from blood nourishing muscle and tendon.”
Rhizoma Polygonati Odorati: sweet in the mouth, property is put down；Attach to the lung and stomach meridians.Nourishing YIN and moistening the lung, nourishing the stomach to promote the production of body fluid.Main cough caused by dryness, chronic cough, calentura the moon liquid consumption hinders it Dry throat and mouth, interior-heat quenches one's thirst, deficiency of YIN diseases caused by exogenous pathogenic factor, dizzy dizziness, muscle arteries and veins spasm and pain.Supplement to the Herbal carries: " main clever, adjust vim and vigour, make us Strong." modern medicine study confirms, to anesthetized rabbit intravenous injection 20% Rhizoma Polygonati Odorati (Shandong Laoshan product) decoct, every 1,2 or 5ml, Blood pressure is all made slowly to increase.
Cortex Acanthopancis: acrid in the mouth, hardship, micro-sweet, warm in nature；Return liver, kidney channel.Wind-damp dispelling, invigorating the liver and kidney, bone and muscle strengthening, arteries and veins of invigorating blood circulation.Main air is trembled with fear Arthralgia chiefly caused by damp pathogen, lumbocrural pain, muscles and bones flaccidity is soft, the decimal a little walking retardation in children, and body void is frail, traumatic injury, fracture, edema, tinea pedis, uncontrolled urination Itch." not Lu " carries: " treating man's impotence, wet under capsule, dribbling urination, woman's pudendal pruritus and pain along the spinal column, two foot pain numbness wind are weak, five slow void Win, invigorating middle warmer benefit essence, hard muscles and bones, Qiang Zhiyi.”
Odontobutis obscura (T. Et S.): sweet in the mouth, warm in nature；Return spleen, stomach warp.Invigorating the spleen and replenishing QI, except temperature diuretic.Main insufficiency of the spleen lack of appetite, edema, eczema, scabies. Yao Kecheng " food book on Chinese herbal medicine " carries: " tonifying the spleen and stomach, benefit vigour support flourish blood.”
The present invention compared with prior art, has the advantages that
Compatibility of drugs of the present invention is suitable, brings out the best in each other, and has bone and muscle strengthening, arteries and veins of invigorating blood circulation, liver and kidney tonifying, nourishing YIN and moistening the lung, nourishing the stomach Promote the production of body fluid, the effect such as invigorating the spleen and regulating the stomach, mind tranquilizing and the heart calming, all medicines drug effect that is harmonious can be gone directly diseased region, causes for treatment hypotension The symptoms such as dizziness, headache, inappetence, fatigue, green around the gills, dyspepsia, four cold extremities, cardiopalmus, dyspnea have and take effect Hurry up, the advantage such as cure rate is high, have no side effect, safe ready, and low price, easily prepare, clinic be widely popularized Application.
Detailed description of the invention
Below in conjunction with specific embodiment, the present invention is further elaborated.
Embodiment 1
The raw material of effective ingredient of the present invention forms and weight is:
The processing step of process for preparing medicine of the present invention is:
(1) Radix seu Caulis Verntilaginis Leiocarpae, Fructus Pandani tectorii and Cortex Acanthopancis are immersed yellow wine 3-4 hour, after taking-up, sun dehydration, pour in pot, literary composition Fire parch, after cooling, smashs to pieces and grinds into powder, obtained the fine powder of 120 mesh, standby；
(2) add the water of 8 times amount after Fructus Vitis viniferae, Herba Ecliptae, Folium Vaccinii Bracteati and Rhizoma Polygonati Odorati being mixed, extract 2-3 hour, filter, take Medicinal liquid；In remaining residue, add the water of 6 times amount, extract 1-2 hour, filter, taking liquid；Merge twice medicinal liquid, concentrate The thick paste of relative density 1.10-1.15 at becoming 60 DEG C, drying under reduced pressure, standby；
(3) yellow wine uniform spraying will be used after Chinese angelica slicing, the most vexed, fry with low baking temperature in putting pot, take out, cool, grind into powder, obtain Cross the fine powder of 160, standby；
(4) add cooked Mel after being cut into slices by Radix Glycyrrhizae a little with boiled water, mix thoroughly, the most vexed, fry to becoming with slow fire in putting pot Buff, tack-free for degree, taking-up cools, and grinds into powder, obtains the fine powder of 180 mesh, standby；
(5) Arillus Longan, Radix Rehmanniae Preparata, Poria, Fructus Jujubae, Stephanotis chunii Tsiang, Ganoderma and Odontobutis obscura (T. Et S.) are put in container, be firstly added 10- 15 times amount distilled water immersions are after 4-5 hour, heated and boiled 3-4 hour, extract；Second time adds 8-10 times amount distilled water heated and boiled 2-3 hour, extract；Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts；United extraction liquid, filters, obtains filtrate Standby；
(6) fine powder, thick paste and the filtrate mixing that step (1)-step (5) prepares, makes tablet, is described for controlling Treat hypotensive medicine.
Usage and dosage: oral, every day 2 times, each 1,10 days is a course for the treatment of, can fully recover 3 to 5 courses for the treatment of, the state of an illness is tight Severe one is followed the doctor's advice the meal with wine amount of adding.
Embodiment 2
The raw material of effective ingredient of the present invention forms and weight is:
The process for preparing medicine processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 3
The raw material of effective ingredient of the present invention forms and weight is:
The process for preparing medicine processing step of the present embodiment and usage and dosage are same as in Example 1.
Embodiment 4
The raw material of effective ingredient of the present invention forms and weight is:
The process for preparing medicine processing step of the present embodiment and usage and dosage are same as in Example 1.
Clinical data:
1, case selection:
Selecting the hypotensive 320 example clinical observation that my institute or outer court make a definite diagnosis, patient is randomly divided into two groups, treatment group 160 examples, wherein male 80 example, women 80 example, age 20-75 year, 43.8 years old mean age, course of disease 1-10；Matched group 160 Example, wherein male 80 example, women 80 example, age 20-75 year, 43.2 years old mean age, course of disease 1-10.The disease of two groups of cases Journey, degrees of symptoms are basically identical, without significant difference, have comparability.
2, medicament selection:
Treatment group patient takes medicine of the present invention, every day 2 times, each 1, warm water delivery service in half an hour after meal, 10 days Being a course for the treatment of, take 3 to 5 courses for the treatment of continuously and can fully recover, the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
Matched group takes ginseng stilbene yang invigorating blood enriching capsule, by specification use, and the person of being in a bad way follows the doctor's advice the meal with wine amount of adding.
3, efficacy determination:
(1) cure: dizziness, headache, inappetence, fatigue, green around the gills, dyspepsia, four cold extremities, cardiopalmus, breathing are stranded The transference cures such as difficulty, physical recovery is normal.
(2) effective: above-mentioned symptom has been alleviated.
(3) invalid: disease is unchanged.
4, result:
Taking in the treatment group of medicine of the present invention, cure 120 examples, effective 37 examples, invalid 3 examples, cure rate is 75%, always has Efficiency 98.1%.
Curing 50 examples, effective 50 examples, invalid 60 examples in matched group, cure rate is 31.2%, total effective rate 62.5%.
Result above shows, treatment group cure rate and total effective rate are apparently higher than matched group.
Model case is illustrated:
1, Wang, female, 68 years old, retired worker, people from Suqian, Jiangsu.Patient suffers from hypotension 8 years, dizziness, fatigue, face often occurs The symptoms such as color is pale, cardiopalmus, dyspnea, blood pressure 90/60 millimetres of mercury；Took multi-medicament not cure, be situated between by friend Continue to our hospital.After taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom is clearly better；Continue to take medicine 2 of the present invention The individual course for the treatment of, above-mentioned symptom disappears, and recovery from illness is followed up a case by regular visits to, do not recurred.
2, Yuan, man, 52 years old, manager, people from Jilin Baishan.There is giddy, the symptom such as weak, nervous, blood pressure 80/50 in patient Millimetres of mercury, routine blood test is normal, and heart rate 60 beats/min uses multiple therapy methods at local hospital, and effect is the most notable.By Friend introduces to our hospital.Taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom is clearly better；Continue to take the present invention 3 courses for the treatment of of medicine, above-mentioned symptom disappears, and recovery from illness is followed up a case by regular visits to, do not recurred.
3, fourth, man, 45 years old, food factory workman, Chao County of Anhui Province Lakers.Patient occurred dizzy, weary without obvious inducement before 2 years The symptoms such as power, nervous, dyspnea, go to a doctor at local hospital, examine as hypotension, are interrupted and giving Drug therapy, do not take a favorable turn.Closely Within 1 year, conditions of patients substantially increases the weight of, to our hospital.Taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom starts to take a turn for the better；Continue Continuous take 2 courses for the treatment of of medicine of the present invention after, above-mentioned symptom disappears, recovery from illness, follows up a case by regular visits to, does not recurs.
4, Chen, man, 38 years old, programmer, Bay, Ningde, Fujian Province people.Patient suffers from hypotension more than 3 years, through multiple hospitals treatment all Do not effect a radical cure.Introduce to our hospital by local doctor, check blood pressure 75/50 millimetres of mercury, dizzy during morbidity, inappetence, Dyspepsia, cardiopalmus.Taking 3 courses for the treatment of of medicine of the present invention, above-mentioned symptom takes a turn for the better；Continue to take medicine of the present invention 2 treatment Cheng Hou, above-mentioned symptom disappears, and recovery from illness is followed up a case by regular visits to, do not recurred.
5, Zhang, female, 23 years old, student, Hubei Xiaogan people.There is dizziness, inappetence, fatigue, digestion not before 3 years in patient Good, cardio palmus shape, is diagnosed as hypotension in local hospital inspection, does not take a favorable turn after treatment, introduces my institute by friend Medical.Taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom takes a turn for the better；After continuing to take 2 courses for the treatment of of medicine of the present invention, above-mentioned Transference cure, recovery from illness, follow up a case by regular visits to, do not recur.
6, in certain, female, 20 years old, student, people from Jiaozhuo, Henan.Patient without obvious inducement occur dizziness, inappetence, fatigue, The symptom such as dyspepsia, green around the gills, increases the weight of summer.Go to a doctor and local hospital, be diagnosed as hypotension on inspection, through Drug therapy After do not take a favorable turn, the most to our hospital.After taking 2 courses for the treatment of of medicine of the present invention, above-mentioned symptom takes a turn for the better；Continue to take this After 2 courses for the treatment of of bright medicine, above-mentioned symptom disappears, and recovery from illness is followed up a case by regular visits to, do not recurred.

Claims (5)

1. one kind is used for treating hypotensive medicine, it is characterised in that: make raw material composition and the weight of described effective ingredient Amount number is:
Radix seu Caulis Verntilaginis Leiocarpae 23-56 part Fructus Vitis viniferae 18-50 part Radix Angelicae Sinensis 18-50 part Herba Ecliptae 15-47 part
Fructus Pandani tectorii 13-45 part Radix Glycyrrhizae 13-45 part Arillus Longan 12-36 part Radix Rehmanniae Preparata 11-35 part
Poria 11-35 part Fructus Jujubae 11-35 part Stephanotis chunii Tsiang 10-31 part Ganoderma 10-31 part
Folium Vaccinii Bracteati 8-28 part Rhizoma Polygonati Odorati 8-28 part Cortex Acanthopancis 7-27 part Odontobutis obscura (T. Et S.) 5-21 part.
One the most according to claim 1 is used for treating hypotensive medicine, it is characterised in that: make described medicine effective The raw material of composition forms and parts by weight are:
48 portions of Fructus Vitis viniferaes of Radix seu Caulis Verntilaginis Leiocarpae, 42 portions of Herba Ecliptaes of 42 parts of Radix Angelicae Sinensis 39 parts
37 portions of Radix Glycyrrhizaes of Fructus Pandani tectorii, 30 parts of Radix Rehmanniae Preparata of 37 portions of Arillus Longans 29 parts
29 portions of Fructus Jujubaes of Poria, 26 portions of Ganodermas of 29 parts of Stephanotis chunii Tsiangs 26 parts
23 portions of Rhizoma Polygonati Odorati of Folium Vaccinii Bracteati, 22 parts of Odontobutis obscura (T. Et S.) of 23 parts of Cortex Acanthopanciss 17 parts.
One the most according to claim 1 is used for treating hypotensive medicine, it is characterised in that: make described medicine effective The raw material of composition forms and parts by weight are:
40 portions of Fructus Vitis viniferaes of Radix seu Caulis Verntilaginis Leiocarpae, 34 portions of Herba Ecliptaes of 34 parts of Radix Angelicae Sinensis 31 parts
29 portions of Radix Glycyrrhizaes of Fructus Pandani tectorii, 24 parts of Radix Rehmanniae Preparata of 29 portions of Arillus Longans 23 parts
23 portions of Fructus Jujubaes of Poria, 21 portions of Ganodermas of 23 parts of Stephanotis chunii Tsiangs 21 parts
18 portions of Rhizoma Polygonati Odorati of Folium Vaccinii Bracteati, 17 parts of Odontobutis obscura (T. Et S.) of 18 parts of Cortex Acanthopanciss 13 parts.
One the most according to claim 1 is used for treating hypotensive medicine, it is characterised in that: make described medicine effective The raw material of composition forms and parts by weight are:
32 portions of Fructus Vitis viniferaes of Radix seu Caulis Verntilaginis Leiocarpae, 26 portions of Herba Ecliptaes of 26 parts of Radix Angelicae Sinensis 23 parts
21 portions of Radix Glycyrrhizaes of Fructus Pandani tectorii, 18 parts of Radix Rehmanniae Preparata of 21 portions of Arillus Longans 17 parts
17 portions of Fructus Jujubaes of Poria, 16 portions of Ganodermas of 17 parts of Stephanotis chunii Tsiangs 16 parts
13 portions of Rhizoma Polygonati Odorati of Folium Vaccinii Bracteati, 12 parts of Odontobutis obscura (T. Et S.) of 13 parts of Cortex Acanthopanciss 9 parts.
5. the preparation method for treating hypotensive medicine as described in any one of claim 1-4, it is characterised in that: Comprise the following steps that:
(1) Radix seu Caulis Verntilaginis Leiocarpae, Fructus Pandani tectorii and Cortex Acanthopancis are immersed yellow wine 3-4 hour, after taking-up, sun dehydration, to pour in pot, slow fire is fried System, after cooling, smashs to pieces and grinds into powder, obtained the fine powder of 120 mesh, standby；
(2) add the water of 8 times amount after Fructus Vitis viniferae, Herba Ecliptae, Folium Vaccinii Bracteati and Rhizoma Polygonati Odorati being mixed, extract 2-3 hour, filter, taking liquid； In remaining residue, add the water of 6 times amount, extract 1-2 hour, filter, taking liquid；Merge twice medicinal liquid, be condensed into 60 DEG C The thick paste of lower relative density 1.10-1.15, drying under reduced pressure, standby；
(3) yellow wine uniform spraying will be used after Chinese angelica slicing, the most vexed, fry with low baking temperature in putting pot, take out, cool, grind into powder, obtained The fine powder of 160, standby；
(4) add cooked Mel after being cut into slices by Radix Glycyrrhizae a little with boiled water, mix thoroughly, the most vexed, fry to becoming deep yellow with slow fire in putting pot Color, tack-free for degree, taking-up cools, and grinds into powder, obtains the fine powder of 180 mesh, standby；
(5) Arillus Longan, Radix Rehmanniae Preparata, Poria, Fructus Jujubae, Stephanotis chunii Tsiang, Ganoderma and Odontobutis obscura (T. Et S.) are put in container, be firstly added 10-15 times Amount distilled water immersion after 4-5 hour, heated and boiled 3-4 hour, extract；Second time adds 8-10 times amount distilled water heated and boiled 2-3 Hour, extract；Third time adds 6-8 times amount distilled water heated and boiled 1-2 hour, extracts；United extraction liquid, filters, obtains filtrate standby With；
(6) fine powder, thick paste and the filtrate mixing that step (1)-step (5) prepares, makes tablet, is described low for treating The medicine of blood pressure.
CN201610621536.4A 2016-07-30 2016-07-30 Medicine for treating hypotension and preparation method thereof Pending CN105998667A (en)

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Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050349A (en) * 2017-05-04 2017-08-18 南京苏新智慧社区服务有限公司 A kind of cream taste of toxin expelling promoting blood circulation and its preparation method and application

Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1338291A (en) * 2001-09-13 2002-03-06 徐凤玉 Chinese medicine for treating hypotension
CN1488366A (en) * 2002-10-10 2004-04-14 王太兴 Chinese medicine for treating hypotension and preparing method thereof

Patent Citations (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN1338291A (en) * 2001-09-13 2002-03-06 徐凤玉 Chinese medicine for treating hypotension
CN1488366A (en) * 2002-10-10 2004-04-14 王太兴 Chinese medicine for treating hypotension and preparing method thereof

Cited By (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN107050349A (en) * 2017-05-04 2017-08-18 南京苏新智慧社区服务有限公司 A kind of cream taste of toxin expelling promoting blood circulation and its preparation method and application

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Application publication date: 20161012