CN105997008A - Adaptive adjustment system and method for signals of biosensors - Google Patents

Adaptive adjustment system and method for signals of biosensors Download PDF

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Publication number
CN105997008A
CN105997008A CN201610473883.7A CN201610473883A CN105997008A CN 105997008 A CN105997008 A CN 105997008A CN 201610473883 A CN201610473883 A CN 201610473883A CN 105997008 A CN105997008 A CN 105997008A
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CN
China
Prior art keywords
potentiometer
resistance
biosensor
voltage
output
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CN201610473883.7A
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Chinese (zh)
Inventor
张贯京
陈兴明
张少鹏
高伟明
李慧玲
周起有
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Shenzhen Beiwo Deke Biotechnology Research Institute Co Ltd
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Shenzhen Beiwo Deke Biotechnology Research Institute Co Ltd
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Application filed by Shenzhen Beiwo Deke Biotechnology Research Institute Co Ltd filed Critical Shenzhen Beiwo Deke Biotechnology Research Institute Co Ltd
Priority to CN201610473883.7A priority Critical patent/CN105997008A/en
Priority to PCT/CN2016/101871 priority patent/WO2017219544A1/en
Publication of CN105997008A publication Critical patent/CN105997008A/en
Pending legal-status Critical Current

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Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/72Signal processing specially adapted for physiological signals or for diagnostic purposes
    • A61B5/7225Details of analog processing, e.g. isolation amplifier, gain or sensitivity adjustment, filtering, baseline or drift compensation

Abstract

The invention discloses an adaptive adjustment system and method for signals of biosensors. The method comprises the following steps: controlling a double-throw switch to be off to enable the voltage difference between a positive electrode input end and a negative electrode input end of a biosensor circuit to be zero; adjusting the resistance value of a first potentiometer and synchronously adjusting the resistance value of a second potentiometer to adjust the voltage at an output end of the biosensor circuit to be zero; controlling the double-throw switch to be on to enable bioelectrical signals detected by a detection head to be output to the biosensor circuit; detecting the strength of the bioelectrical signals output by the biosensor circuit; adjusting the resistance value of a third potentiometer and synchronously adjusting the resistance value of a fourth potentiometer to dynamically adjust the bioelectrical signals, in a preset strength threshold range, output by the biosensor circuit. The method has the advantages that the phenomenon of circuit temperature drift of the biosensor can be eliminated, the bioelectrical signals with appropriate strength can be output adaptively, the output electrical characteristics of the biosensor are stabilized, and the sensitivity of the biosensor is improved.

Description

The signal adaptive regulation system and method for biosensor
Technical field
The present invention relates to field of biosensors, the signal adaptive particularly relating to a kind of biosensor is adjusted Joint system and method.
Background technology
In biosensor circuit, even if being zero by input voltage, measure output with sensitive direct current table End, also can change output voltage slowly.This input voltage is zero and output voltage is not zero and delays The phenomenon of slow change, referred to as null offset phenomenon.In biosensor circuit, the change of any parameter, The change varying with temperature such as the fluctuation of supply voltage, aging, the semiconductor element parameter of element and producing, All will produce the drift of output voltage.It is to produce by the change of the semiconductor device parameter caused by variations in temperature The main cause of raw null offset phenomenon, the most also referred to as null offset is temperature drift.
Usually, biosensor (such as pressure transducer, pulse transducer or heart rate sensor etc.) The sensitivity required is the highest, if the generation temperature drift of this type of biosensor circuit, could be obvious Affect the change of resistance value and cause output voltage unstable, thus have influence on the sensitivity of biosensor. Additionally, due to the bioelectrical signals (such as blood pressure, pulse or heart rate signal) of human body generation is strong time possible Time weak, the bioelectrical signals that the detecting head of biosensor senses is the most at times strong and at other times weak, in order to allow biological biography The bioelectrical signals of sensor output appropriate signals intensity, it is therefore desirable to carry out the bioelectrical signals sensed Carry out again exporting after carrying out Automatic adjusument obtaining stable bioelectrical signals.
Summary of the invention
Present invention is primarily targeted at signal adaptive regulation system and the side that a kind of biosensor is provided Method, it is intended to solve biosensor circuit and cause sensitivity the highest because of temperature drift and cannot be automatically adjusted The problem of bioelectrical signals intensity.
For achieving the above object, the invention provides the signal adaptive regulation system of a kind of biosensor, It is applied in the single-chip microcomputer of biosensor, it is characterised in that described single-chip microcomputer connects biological first electricity Position device, the second potentiometer, the 3rd potentiometer, the 4th potentiometer and biosensor circuit, this biology Sensor circuit is connected by the first potentiometer and the second potentiometer commutator, and this commutator connects Having detecting head, the first potentiometer includes that the first balancing resistance, the second potentiometer include the second balancing resistance, 3rd potentiometer includes the 3rd balancing resistance, and the 4th potentiometer includes the 4th balancing resistance, described single-chip microcomputer End is controlled including the first control end, the second control end, the 3rd control end, the 4th control end and the 5th, Wherein, described signal adaptive regulation system includes:
Switch control module, makes biosensor electricity for controlling end control commutator disconnection by the 5th The electrode input end on road and the voltage difference of negative input are zero, when the outfan electricity of biosensor circuit When pressure is zero, controls end by the 5th and control the bioelectrical signals that commutator Guan Bi makes detecting head measure Output is to biosensor circuit;
Temperature drift cancellation module, controls the contact slip of the first balancing resistance for controlling end by first To change the resistance value of the first potentiometer and touching by second control end Synchronization Control the second balancing resistance Head slides and is set to zero by the output end voltage of biosensor circuit changing the resistance value of the second potentiometer;
Signal adaptive adjustment module, for detecting the letter of the bioelectrical signals of biosensor circuit output Whether number intensity is in preset strength threshold range, at the signal intensity of the bioelectrical signals of output In preset strength threshold range, control end by the 3rd and control the contact slip of the 3rd balancing resistance to change Become the resistance value of the 3rd potentiometer and slided by the contact of the 4th control end Synchronization Control the 4th balancing resistance The dynamic resistance value to change the 4th potentiometer dynamically regulates the output end voltage of biosensor circuit, makes The signal intensity of the bioelectrical signals of biosensor circuit output is in preset strength threshold range.
Preferably, described temperature drift cancellation module is additionally operable to the output end voltage when biosensor circuit When being zero, control end by first and control the contact of the first balancing resistance and control the by the second control end The contact of two balancing resistance stops sliding and fixed position simultaneously.
Preferably, described preset strength threshold value pre-sets and is stored in the memorizer of described single-chip microcomputer, Strength criterion as the bioelectrical signals of biosensor circuit output.
Preferably, described first potentiometer also includes the first voltage regulation resistance, this first voltage regulation resistance and first Balancing resistance is connected, and described second potentiometer also includes the second voltage regulation resistance, this second voltage regulation resistance and the Two balancing resistance series connection, described first voltage regulation resistance and the second voltage regulation resistance for keep the first potentiometer and Second potentiometer output burning voltage is not damaged by with protection biosensor circuit.
Preferably, described 3rd potentiometer also includes the 3rd voltage regulation resistance, the 3rd voltage regulation resistance and the 3rd Balancing resistance is connected, and described 4th potentiometer also includes the 4th voltage regulation resistance, the 4th voltage regulation resistance and the Four balance resistant series, described 3rd voltage regulation resistance and the 4th voltage regulation resistance for keep the 3rd potentiometer and 4th potentiometer output burning voltage makes the bioelectrical signals that biosensor circuit output is stable.
For achieving the above object, present invention also offers the signal adaptive regulation side of a kind of biosensor Method, is applied in the single-chip microcomputer of biosensor, described single-chip microcomputer connect have biological first potentiometer, the Two potentiometers, the 3rd potentiometer, the 4th potentiometer and biosensor circuit, this biosensor electricity Road is connected by the first potentiometer and the second potentiometer commutator, and this commutator connects detecting head, First potentiometer includes that the first balancing resistance, the second potentiometer include the second balancing resistance, the 3rd potentiometer Including the 3rd balancing resistance, the 4th potentiometer includes that the 4th balancing resistance, described single-chip microcomputer include the first control End processed, the second control end, the 3rd control end, the 4th control end and the 5th control end, wherein, described Signal adaptive control method includes step:
Control end control commutator by the 5th and disconnect the electrode input end making biosensor circuit with negative The voltage difference of pole input is zero;
Control end by first and control the contact slip of the first balancing resistance with the resistance changing the first potentiometer Value and the contact by second control end Synchronization Control the second balancing resistance slide to change the second potentiometer Resistance value the output end voltage of biosensor circuit is set to zero;
When the output end voltage of biosensor circuit is zero, controls end by the 5th and control commutator The bioelectrical signals that Guan Bi makes detecting head measure exports to biosensor circuit;
Whether the signal intensity of the bioelectrical signals of detection biosensor circuit output is in preset strength threshold In the range of value;
When the signal intensity of the bioelectrical signals of output is not in preset strength threshold range, by the 3rd Control end to control the contact of the 3rd balancing resistance and slide to change the resistance value of the 3rd potentiometer and by the Four contacts controlling end Synchronization Control the 4th balancing resistance slide and move with the resistance value of change the 4th potentiometer The output end voltage of state regulation biosensor circuit, makes the bioelectrical signals that biosensor circuit exports Signal intensity be in preset strength threshold range.
Preferably, the signal adaptive control method of described biosensor further comprises the steps of: when biology passes When the output end voltage of sensor circuit is zero, by first control end control the first balancing resistance contact and The contact being controlled the second balancing resistance by the second control end stops sliding and fixed position simultaneously.
Preferably, described preset strength threshold value pre-sets and is stored in the memorizer of described single-chip microcomputer, Strength criterion as the bioelectrical signals of biosensor circuit output.
Preferably, described first potentiometer also includes the first voltage regulation resistance, this first voltage regulation resistance and first Balancing resistance is connected, and described second potentiometer also includes the second voltage regulation resistance, this second voltage regulation resistance and the Two balancing resistance series connection, described first voltage regulation resistance and the second voltage regulation resistance for keep the first potentiometer and Second potentiometer output burning voltage is not damaged by with protection biosensor circuit.
Preferably, described 3rd potentiometer also includes the 3rd voltage regulation resistance, the 3rd voltage regulation resistance and the 3rd Balancing resistance is connected, and described 4th potentiometer also includes the 4th voltage regulation resistance, the 4th voltage regulation resistance and the Four balance resistant series, described 3rd voltage regulation resistance and the 4th voltage regulation resistance for keep the 3rd potentiometer and 4th potentiometer output burning voltage makes the bioelectrical signals that biosensor circuit output is stable.
Compared to prior art, the signal adaptive regulation system and method for biosensor of the present invention Use technique scheme, achieve following technique effect, can either automatically eliminate biosensor and produce Circuit temperature drift phenomenon, eliminate circuit temperature drift phenomenon and the sensitivity of biosensor produced Adverse effect, the biology of proper strength can be exported again adaptively according to the power of bioelectrical signals The signal of telecommunication, thus stabilize biosensor output electrical characteristic, improve the sensitivity of biosensor, Achieve the effect that the bioelectrical signals of biosensor self adaptation measurand is strong and weak.
Accompanying drawing explanation
Fig. 1 is the applied environment of the signal adaptive regulation system preferred embodiment of biosensor of the present invention Schematic diagram;
Fig. 2 is the functional module of the signal adaptive regulation System Preferred embodiments of biosensor of the present invention Schematic diagram;
Fig. 3 is the flow chart of the signal adaptive control method preferred embodiment of biosensor of the present invention.
The realization of the object of the invention, functional characteristics and advantage will in conjunction with the embodiments, do referring to the drawings further Explanation.
Detailed description of the invention
By further illustrating the technological means and effect that the present invention taked by reaching above-mentioned purpose, below In conjunction with accompanying drawing and preferred embodiment, detailed description of the invention, structure, feature and effect thereof of the present invention is entered Row describes in detail.Should be appreciated that specific embodiment described herein only in order to explain the present invention, and It is not used in the restriction present invention.
As it is shown in figure 1, the signal adaptive regulation system that Fig. 1 is biosensor of the present invention is preferably implemented The applied environment schematic diagram of example.In the present embodiment, described signal adaptive regulation system 10 is applied to list In sheet machine 8, this single-chip microcomputer 8 be connected to first potentiometer the 3, second potentiometer the 4, the 3rd potentiometer 5, 4th potentiometer 6 and biosensor circuit 7.Described biosensor circuit 7 is by the first potentiometer 3 and second potentiometer 4 connect have commutator 2, this commutator 2 connects detecting head 1.Specifically, Two outfans of described detecting head 1 are connected to two inputs of commutator 2, described commutator 2 An outfan be connected to the input of the first potentiometer 3, another output of described commutator 2 End is connected to the input of the second potentiometer 4.The outfan of the first potentiometer 3 is connected to biosensor The electrode input end of circuit 7, the outfan of the second potentiometer 4 is connected to the negative of biosensor 7 circuit Pole input, the outfan of described biosensor circuit 7 is connected to the signal input part of single-chip microcomputer 8, One end of 3rd potentiometer 5 is connected to the electrode input end of biosensor circuit 7, the 3rd potentiometer 5 The other end be earth terminal, the negative pole that one end of the 4th potentiometer 6 is connected to biosensor circuit 7 is defeated Entering end, one end of the 4th potentiometer 6 is connected to the outfan of biosensor circuit 7.Described double-throw is opened Close 2, first potentiometer the 3, second potentiometer the 4, the 3rd potentiometer 5 and the 4th potentiometer 6 is connected to On single-chip microcomputer 8.Described single-chip microcomputer 8 is microprocessor, single-chip microcomputer, signal processing chip or signal control Coremaking sheet.Described preset strength threshold range pre-sets and is stored in described single-chip microcomputer 8, as life The strength criterion of the bioelectrical signals of thing sensor circuit 7 output.Described biosensor circuit 7 uses Existing biosensor (such as pressure transducer, pulse transducer or heart rate sensor etc.) existing letter Number process circuit, generally comprise digital-to-analogue (A/D) change-over circuit, signal filter circuit etc., the present embodiment is not It is specifically addressed.
In the present embodiment, described first potentiometer 3 includes the first balancing resistance DR1 and the first voltage stabilizing electricity Resistance R1, the first balancing resistance DR1 and the first voltage regulation resistance R1 series connection.Described second potentiometer 4 includes Second balancing resistance DR2 and the second voltage regulation resistance R2, the second balancing resistance DR2 and the second voltage regulation resistance R2 connects.Described 3rd potentiometer 5 includes the 3rd balancing resistance DR3 and the 3rd voltage regulation resistance R3, the Three balancing resistance DR3 and the 3rd voltage regulation resistance R3 series connection.Described 4th potentiometer 6 includes the 4th balance Resistance DR4 and the 4th voltage regulation resistance R4, the 4th balancing resistance DR4 and the 4th voltage regulation resistance R4 series connection.
Two outfans of described detecting head 1 are connected to two inputs of commutator 2, described double-throw One outfan of switch 2 is connected to the input of the first balancing resistance DR1, described commutator 2 Another outfan is connected to the input of the second balancing resistance DR2, the output of the first voltage regulation resistance R1 End is connected to the electrode input end of biosensor circuit 7, and the outfan of the second voltage regulation resistance R2 is connected to The negative input of biosensor circuit 7, the outfan of described biosensor circuit 7 is connected to list The signal input part S0 of sheet machine 8.First control end S1 of described single-chip microcomputer 8 is connected to the first balancing resistance The control end of DR1, the second control end S2 of described single-chip microcomputer 8 is connected to the second balancing resistance DR2 Control end.3rd control end S3 of described single-chip microcomputer 8 is connected to the control end of the 3rd balancing resistance DR3, One end of 3rd balancing resistance DR3 is earth terminal, and the other end of the 3rd balancing resistance DR3 is connected to the 3rd One end of voltage regulation resistance R3, the other end of the 3rd voltage regulation resistance R3 is connected to biosensor circuit 7 Electrode input end.4th control end S4 of described single-chip microcomputer 8 is connected to the control of the 4th balancing resistance DR42 End processed, it is (that is: biological that one end of the 4th balancing resistance DR4 is connected to the signal input part S0 of single-chip microcomputer 8 The outfan of sensor circuit 7), the other end of the 4th balancing resistance DR4 is connected to the 4th voltage regulation resistance One end of R4, the other end of the 4th voltage regulation resistance R4 is connected to the negative pole input of biosensor circuit 7 End.5th control end S5 of described single-chip microcomputer 8 is connected to the control end of described commutator 2, for certainly Being opened or closed of dynamic control commutator 2.
Described single-chip microcomputer 8 is used for controlling commutator 2 when disconnecting, by regulating the first potentiometer 3 and The voltage-regulation that biosensor circuit 7 produces because of temperature drift phenomenon is by the resistance value of two potentiometers 4 Zero.Described single-chip microcomputer 8 is additionally operable to control commutator 2 when closing, by regulation the 3rd potentiometer 5 He The bioelectrical signals intensity that the resistance value of the 4th potentiometer 5 makes described biosensor 7 circuit export is in In preset strength threshold range.
In eliminating the temperature drift phenomena process that biosensor circuit 7 produces, when the first balancing resistance When the contact of DR1 and the second balancing resistance DR2 slides into zero end resistance value, producing higher voltage may Biosensor circuit 7 can be damaged.Therefore, the present embodiment uses the first voltage regulation resistance R1 and second steady Piezoresistance R2 ensures the first potentiometer 3 and stability of the second potentiometer 4 output voltage.When first is flat When the contact of weighing apparatus resistance DR1 and the second balancing resistance DR2 slides, described first voltage regulation resistance R1 and the Two voltage regulation resistance R2 are for keeping the first potentiometer 3 and the second potentiometer 4 to export burning voltage, thus protect Protect biosensor circuit 7 to damage because of overtension.
During the signal intensity of the bioelectrical signals of regulation biosensor circuit 7 output, when the 3rd When the contact of balancing resistance DR3 and the 4th balancing resistance DR4 slides into zero end resistance value, produce higher Voltage may biosensor circuit 7.Therefore, the present embodiment uses the 3rd voltage regulation resistance R3 and the Four voltage regulation resistance R4 ensure the 3rd potentiometer 5 and the stability of the 4th potentiometer 6 output voltage.When When the contact of three balancing resistance DR3 and the 4th balancing resistance DR4 slides, described 3rd voltage regulation resistance R3 Make raw with the 4th voltage regulation resistance R2 for keeping the 3rd potentiometer 5 and the 4th potentiometer 6 to export burning voltage Thing sensor circuit 7 exports stable bioelectrical signals.
As in figure 2 it is shown, the signal adaptive regulation system that Fig. 2 is biosensor of the present invention is preferable to carry out The high-level schematic functional block diagram of example.In the present embodiment, described signal adaptive regulation system 10 is installed also Running in described single-chip microcomputer 8, this single-chip microcomputer 8 also include but not limited to, microcontroller 11 and Memorizer 12.Described signal adaptive regulation system 10 include but not limited to, switch control module 101, temperature drift cancellation module 103 and signal adaptive adjustment module 103.Mould alleged by the present invention Block refer to a kind of can be performed by the microcontroller 11 of single-chip microcomputer 8 and the one of fixing function can be completed Family computer programmed instruction section, it is stored in the memorizer 12 of single-chip microcomputer 8.
In the present embodiment, described microcontroller 11 can be a kind of microprocessor, micro-control unit (MCU), signal processing chip or have signal control function signaling control unit.Described storage Device 12 can be a kind of read only memory ROM, electrically-erasable memorizer EEPROM or flash Device FLASH etc..
Shown in Fig. 1, described switch control module 101 is used for when detecting head 1 unlatching measurement is tested right During as bioelectrical signals (the such as electrocardiosignal) of (such as human body), control end S5 by the 5th and control Commutator 2 disconnects and makes the electrode input end of biosensor circuit 7 with the voltage difference of negative input be Zero.When the output end voltage of biosensor circuit 7 is zero, described switch control module 101 is also used The biological telecommunications that commutator 2 Guan Bi makes the measurement of described detecting head 1 arrive is controlled in controlling end S5 by the 5th Number output is to described biosensor circuit 7.
Described temperature drift cancellation module 102 controls the first balancing resistance for controlling end S1 by first The contact of DR1 slides to change the resistance value of the first potentiometer 3 and synchronizes control by the second control end S2 The contact making the second balancing resistance DR2 slides to change the resistance value of the second potentiometer 4 by biosensor The output end voltage of circuit 7 is set to zero.When the output end voltage of biosensor circuit 7 is zero, institute State temperature drift cancellation module 102 to be additionally operable to control the first balancing resistance DR1 by the first control end S1 Contact and control end S2 by second and control the contact of the second balancing resistance DR2 and stop sliding also simultaneously Fixed position, now can eliminate the temperature drift phenomenon of biosensor circuit 7 generation to bio-sensing The adverse effect that the sensitivity of device 7 produces, stabilizes the electrical characteristic of biosensor circuit 7 output.
When the output end voltage of biosensor circuit 7 is zero, i.e. may utilize detecting head 1 and measure tested The bioelectrical signals of object.The bioelectrical signals produced due to human body (believe by such as blood pressure, pulse or heart rate Number) may be at times strong and at other times weak, the bioelectrical signals that the detecting head 1 of biosensor senses is the most at times strong and at other times weak, In order to allow biosensor export the bioelectrical signals of appropriate signals intensity, it is therefore desirable to carry out sensing Bioelectrical signals carry out Automatic adjusument after carry out again exporting obtaining stable bioelectrical signals.In this reality Executing in example, described signal adaptive adjustment module 103 is for detecting the life of biosensor circuit 7 output Whether the signal intensity of the thing signal of telecommunication is in preset strength threshold range, when the bioelectrical signals exported Signal intensity is not in preset strength threshold range, controls end S3 by the 3rd and controls the 3rd balancing resistance The contact of DR3 slides to change the resistance value of the 3rd potentiometer 5 and synchronizes control by the 4th control end S4 The contact slip making the 4th balancing resistance DR4 dynamically regulates life with the resistance value changing the 4th potentiometer 6 The output end voltage of thing sensor circuit 7, makes the letter of the bioelectrical signals that biosensor circuit 7 exports Number intensity is in preset strength threshold range, thus stabilizes the biology of biosensor circuit 7 output Electrical signal intensity, achieves the effect that the bioelectrical signals of biosensor self adaptation measurand is strong and weak.
As it is shown on figure 3, the signal adaptive control method that Fig. 3 is biosensor of the present invention is preferable to carry out The flow chart of example.In the present embodiment, described signal adaptive control method is applied to biosensor Single-chip microcomputer 8 in, shown in Fig. 1 and Fig. 2, the method comprising the steps of S31 is to step S37:
Step S31, the positive pole being made biosensor circuit by the 5th control end control commutator disconnection is defeated The voltage difference entering end and negative input is zero;Specifically, measurement measurand (example is opened when detecting head 1 Such as human body) bioelectrical signals (such as electrocardiosignal) time, switch control module 101 is by the 5th control End S5 processed controls commutator 2 and disconnects electrode input end and the negative input making biosensor circuit 7 Voltage difference be zero.
Step S32, controls end by first and controls the contact slip of the first balancing resistance to change the first current potential The resistance value of device the contact by second control end Synchronization Control the second balancing resistance slide to change second The output end voltage of biosensor circuit is set to zero by the resistance value of potentiometer;Specifically, temperature drift Cancellation module 102 controls end S1 by first and controls the contact slip of the first balancing resistance DR1 to change The resistance value of the first potentiometer 3 and by second control end S2 Synchronization Control the second balancing resistance DR2 Contact slide with the resistance value output end voltage by biosensor circuit 7 changing the second potentiometer 4 Set to zero.
Step S33, when the output end voltage of biosensor circuit is zero, controls end by first and controls The contact of the first balancing resistance and control end by second and control the contact of the second balancing resistance and stop sliding simultaneously Dynamic;Specifically, when the output end voltage of biosensor circuit 7 is zero, temperature drift cancellation module 102 control end S1 by first controls the contact of the first balancing resistance DR1 and by the second control end S2 The contact controlling the second balancing resistance DR2 stops sliding and fixed position simultaneously, now can eliminate biology The adverse effect that the sensitivity of biosensor 7 is produced by the temperature drift phenomenon that sensor circuit 7 produces, Stabilize the electrical characteristic of biosensor circuit 7 output.
Step S34, controls end by the 5th and controls the biological telecommunications that commutator Guan Bi makes detecting head measure Number output to biosensor circuit;Specifically, it is zero when the output end voltage of biosensor circuit 7 Time, i.e. may utilize detecting head 1 and measure the bioelectrical signals of measurand, now switch control module 101 Control end S5 by the 5th and control the bioelectrical signals that commutator 2 Guan Bi makes the measurement of described detecting head 1 arrive Output is to described biosensor circuit 7.
Step S35, the signal intensity of the bioelectrical signals of detection biosensor circuit output;Specifically, Signal adaptive adjustment module 103 detects the bioelectrical signals of biosensor circuit 7 outfan output Signal intensity.
Step S36, whether signal intensity is in preset strength threshold range;Specifically, signal adaptive Adjustment module 103 judges that the signal intensity of the bioelectrical signals that biosensor circuit 7 outfan exports is No it is in preset strength threshold range.Described preset strength threshold range pre-sets and is stored in monolithic In the memorizer 11 of machine 8, as the strength criterion of the bioelectrical signals of biosensor circuit 7 output. If the signal intensity of biosensor circuit 7 output is not in preset strength threshold range, then flow process is returned Return step S35;If the signal intensity of biosensor circuit 7 output is in preset strength threshold range, Then flow performing step S37.
Step S37, controls end by the 3rd and controls the contact slip of the 3rd balancing resistance to change the 3rd current potential The resistance value of device and the contact by the 4th control end Synchronization Control the 4th balancing resistance slide to change the The resistance value of four potentiometers dynamically regulates the output voltage of biosensor circuit and makes biosensor circuit The signal intensity of the bioelectrical signals of output is in preset strength threshold range;Specifically, signal is adaptive The contact answering adjustment module 103 to control the 3rd balancing resistance DR3 by the 3rd control end S3 slides to change Become the resistance value of the 3rd potentiometer 5 and by the 4th control end S4 Synchronization Control the 4th balancing resistance DR4 Contact slide with change the 4th potentiometer 6 resistance value dynamically regulate the defeated of biosensor circuit 7 Go out terminal voltage, make the signal intensity of the bioelectrical signals that biosensor circuit 7 exports be in preset strength In threshold range, thus stabilize the bioelectrical signals intensity of biosensor circuit 7 output, achieve The effect that the bioelectrical signals of biosensor self adaptation measurand is strong and weak.
The signal adaptive regulation system and method for biosensor of the present invention is by controlling the first current potential The electricity that biosensor circuit 7 is produced by the resistance value of device 3 and the second potentiometer 4 because of temperature drift phenomenon Pressure automatic zero set, eliminates the adverse effect that the sensitivity of biosensor is produced by temperature drift phenomenon, Thus stabilize biosensor output electrical characteristic.Additionally, by controlling the 3rd potentiometer 5 and the 4th The resistance value of potentiometer 6 dynamically regulates the bioelectrical signals of biosensor circuit 7 output and is in properly In signal strength range, thus the bioelectrical signals intensity of stabilate sensor circuit 7 output, obtain The effect that the bioelectrical signals of biosensor self adaptation measurand is strong and weak.
These are only the preferred embodiments of the present invention, not thereby limit the scope of the claims of the present invention, every Utilize equivalent structure or equivalent function conversion that description of the invention and accompanying drawing content made, or directly or Connect and be used in other relevant technical fields, be the most in like manner included in the scope of patent protection of the present invention.

Claims (10)

1. a signal adaptive regulation system for biosensor, is applied to the single-chip microcomputer of biosensor In, it is characterised in that described single-chip microcomputer connects biological first potentiometer, the second potentiometer, the 3rd electricity Position device, the 4th potentiometer and biosensor circuit, this biosensor circuit passes through the first potentiometer Connecting with the second potentiometer and have commutator, this commutator connects detecting head, and the first potentiometer includes First balancing resistance, the second potentiometer includes that the second balancing resistance, the 3rd potentiometer include the 3rd balance electricity Resistance, the 4th potentiometer includes that the 4th balancing resistance, described single-chip microcomputer include the first control end, the second control End, the 3rd control end, the 4th control end and the 5th control end, and wherein, described signal adaptive regulates System includes:
Switch control module, makes biosensor electricity for controlling end control commutator disconnection by the 5th The electrode input end on road and the voltage difference of negative input are zero, when the outfan electricity of biosensor circuit When pressure is zero, controls end by the 5th and control the bioelectrical signals that commutator Guan Bi makes detecting head measure Output is to biosensor circuit;
Temperature drift cancellation module, controls the contact slip of the first balancing resistance for controlling end by first To change the resistance value of the first potentiometer and touching by second control end Synchronization Control the second balancing resistance Head slides and is set to zero by the output end voltage of biosensor circuit changing the resistance value of the second potentiometer;
Signal adaptive adjustment module, for detecting the letter of the bioelectrical signals of biosensor circuit output Whether number intensity is in preset strength threshold range, at the signal intensity of the bioelectrical signals of output In preset strength threshold range, control end by the 3rd and control the contact slip of the 3rd balancing resistance to change Become the resistance value of the 3rd potentiometer and slided by the contact of the 4th control end Synchronization Control the 4th balancing resistance The dynamic resistance value to change the 4th potentiometer dynamically regulates the output end voltage of biosensor circuit, makes The signal intensity of the bioelectrical signals of biosensor circuit output is in preset strength threshold range.
2. the signal adaptive regulation system of biosensor as claimed in claim 1, it is characterised in that Described temperature drift cancellation module is additionally operable to, when the output end voltage of biosensor circuit is zero, pass through First controls end controls the contact of the first balancing resistance and controls the second balancing resistance by the second control end Contact stops sliding and fixed position simultaneously.
3. the signal adaptive regulation system of biosensor as claimed in claim 1, it is characterised in that Described preset strength threshold value pre-sets and is stored in the memorizer of described single-chip microcomputer, as bio-sensing The strength criterion of the bioelectrical signals of device circuit output.
4. the signal adaptive regulation system of biosensor as claimed in claim 1, it is characterised in that Described first potentiometer also includes the first voltage regulation resistance, this first voltage regulation resistance and the series connection of the first balancing resistance, Described second potentiometer also includes the second voltage regulation resistance, this second voltage regulation resistance and the series connection of the second balancing resistance, Described first voltage regulation resistance and the second voltage regulation resistance are for keeping the first potentiometer and the output of the second potentiometer steady Determine voltage to be not damaged by with protection biosensor circuit.
5. the signal adaptive regulation system of biosensor as claimed in claim 1, it is characterised in that Described 3rd potentiometer also includes the 3rd voltage regulation resistance, the 3rd voltage regulation resistance and the series connection of the 3rd balancing resistance, Described 4th potentiometer also includes the 4th voltage regulation resistance, the 4th voltage regulation resistance and the 4th balance resistant series, Described 3rd voltage regulation resistance and the 4th voltage regulation resistance are for keeping the 3rd potentiometer and the output of the 4th potentiometer steady Determining voltage makes biosensor circuit export stable bioelectrical signals.
6. a signal adaptive control method for biosensor, is applied to the single-chip microcomputer of biosensor In, it is characterised in that described single-chip microcomputer connects biological first potentiometer, the second potentiometer, the 3rd electricity Position device, the 4th potentiometer and biosensor circuit, this biosensor circuit passes through the first potentiometer Connecting with the second potentiometer and have commutator, this commutator connects detecting head, described first potentiometer Including the first balancing resistance, the second potentiometer includes that the second balancing resistance, described 3rd potentiometer include Three balancing resistance, described 4th potentiometer includes that the 4th balancing resistance, described single-chip microcomputer include the first control End, the second control end, the 3rd control end, the 4th control end and the 5th control end, wherein, described letter Number adaptive regulation method includes step:
Control end control commutator by the 5th and disconnect the electrode input end making biosensor circuit with negative The voltage difference of pole input is zero;
Control end by first and control the contact slip of the first balancing resistance with the resistance changing the first potentiometer Value and the contact by second control end Synchronization Control the second balancing resistance slide to change the second potentiometer Resistance value the output end voltage of biosensor circuit is set to zero;
When the output end voltage of biosensor circuit is zero, controls end by the 5th and control commutator The bioelectrical signals that Guan Bi makes detecting head measure exports to biosensor circuit;
Whether the signal intensity of the bioelectrical signals of detection biosensor circuit output is in preset strength threshold In the range of value;
When the signal intensity of the bioelectrical signals of output is not in preset strength threshold range, by the 3rd Control end to control the contact of the 3rd balancing resistance and slide to change the resistance value of the 3rd potentiometer and by the Four contacts controlling end Synchronization Control the 4th balancing resistance slide and move with the resistance value of change the 4th potentiometer The output end voltage of state regulation biosensor circuit, makes the bioelectrical signals that biosensor circuit exports Signal intensity be in preset strength threshold range.
7. the signal adaptive control method of biosensor as claimed in claim 6, it is characterised in that The method further comprises the steps of: when the output end voltage of biosensor circuit is zero, controls by first The while that end controlling the contact of the first balancing resistance and controls, by second, the contact that end controls the second balancing resistance Stop sliding and fixed position.
8. the signal adaptive control method of biosensor as claimed in claim 6, it is characterised in that Described preset strength threshold value pre-sets and is stored in the memorizer of described single-chip microcomputer, as bio-sensing The strength criterion of the bioelectrical signals of device circuit output.
9. the signal adaptive control method of biosensor as claimed in claim 6, it is characterised in that Described first potentiometer also includes the first voltage regulation resistance, this first voltage regulation resistance and the series connection of the first balancing resistance, Described second potentiometer also includes the second voltage regulation resistance, this second voltage regulation resistance and the series connection of the second balancing resistance, Described first voltage regulation resistance and the second voltage regulation resistance are for keeping the first potentiometer and the output of the second potentiometer steady Determine voltage to be not damaged by with protection biosensor circuit.
10. the signal adaptive control method of biosensor as claimed in claim 6, its feature exists In, described 3rd potentiometer also includes the 3rd voltage regulation resistance, the 3rd voltage regulation resistance and the 3rd balancing resistance Series connection, described 4th potentiometer also includes the 4th voltage regulation resistance, the 4th voltage regulation resistance and the 4th balance electricity Resistance series connection, described 3rd voltage regulation resistance and the 4th voltage regulation resistance are for keeping the 3rd potentiometer and the 4th current potential Device output burning voltage makes the bioelectrical signals that biosensor circuit output is stable.
CN201610473883.7A 2016-06-25 2016-06-25 Adaptive adjustment system and method for signals of biosensors Pending CN105997008A (en)

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