CN105963201A - Medicinal and edible sugar reducing toothpaste and preparation method thereof - Google Patents
Medicinal and edible sugar reducing toothpaste and preparation method thereof Download PDFInfo
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- CN105963201A CN105963201A CN201610473007.4A CN201610473007A CN105963201A CN 105963201 A CN105963201 A CN 105963201A CN 201610473007 A CN201610473007 A CN 201610473007A CN 105963201 A CN105963201 A CN 105963201A
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- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K8/00—Cosmetics or similar toiletry preparations
- A61K8/18—Cosmetics or similar toiletry preparations characterised by the composition
- A61K8/96—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution
- A61K8/97—Cosmetics or similar toiletry preparations characterised by the composition containing materials, or derivatives thereof of undetermined constitution from algae, fungi, lichens or plants; from derivatives thereof
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- A61K36/06—Fungi, e.g. yeasts
- A61K36/07—Basidiomycota, e.g. Cryptococcus
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
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- A61K36/18—Magnoliophyta (angiosperms)
- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/23—Apiaceae or Umbelliferae (Carrot family), e.g. dill, chervil, coriander or cumin
- A61K36/232—Angelica
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- A61K36/185—Magnoliopsida (dicotyledons)
- A61K36/28—Asteraceae or Compositae (Aster or Sunflower family), e.g. chamomile, feverfew, yarrow or echinacea
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- A61K47/44—Oils, fats or waxes according to two or more groups of A61K47/02-A61K47/42; Natural or modified natural oils, fats or waxes, e.g. castor oil, polyethoxylated castor oil, montan wax, lignite, shellac, rosin, beeswax or lanolin
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Abstract
The invention discloses medicinal and edible sugar reducing toothpaste and a preparation method thereof, relates to toothpaste containing medicinal and edible plant ingredients and a preparation method for the toothpaste containing the medicinal and edible plant ingredients, and aims to solve the problems of undiversified use of conventional toothpaste with a diabetes prevention and treatment effect, poor sugar reducing effects of a traditional Chinese medicinal formula and incapability of protecting health and treating diabetes and complications thereof for a long time. The medicinal and edible sugar reducing toothpaste is prepared from a bitter melon extract, a polygonatum odoratum extract, a platycodon extract, a yam extract, a reed rhizome extract, a reinforcement phase extract, a humectant, an abrasive agent, an adhesive, a foaming agent, a spice, a sweetening agent, a food coloring, a preservative and the balance of de-ionized water. The sugar reducing toothpaste containing the medicinal and edible active ingredients have conventional oral cavity cleaning effects, and in addition, the active ingredients also have the effect of reducing blood sugar, blood fat and blood pressure, and have good healthcare and treatment effects on diabetes, complications thereof, cardiovascular and cerebrovascular diseases and metabolic diseases.
Description
Technical field
The present invention relates to a kind of toothpaste containing medicine food dual purpose plant composition and preparation method thereof.
Background technology
Recently as the raising of living standards of the people, the prevalence of diabetes increases year by year.Diabetes have become in China and have continued
The third-largest chronic disease after tumor, cardiovascular disease, causes huge spirit and financial burden to people.Diabetes pair
The infringement of health is long-term, concealment, gradually and general, and most of patients need to use insulin all the life, and carries out medicine and control
Treat.If but life-time service insulin, and take hypoglycemic medicine, the health of patient can be damaged again because of side effects of pharmaceutical drugs
Healthy.And some medicinal and edible plant has significantly effect to reducing blood glucose, it is substantially without toxicity, side effect, can life-time service,
There is good blood sugar reducing health effect.
The main active ingredient of Fructus Momordicae charantiae is momordica saponins, Fructus Momordicae charantiae glucoside (polysaccharide), water-soluble amino acid, flavonoid, the life of multiple dimension
Element, trace element, mineral etc., have effect of eliminating inflammation and expelling toxin, eliminating phlegm and stopping cough, also can treat hypertension, hyperlipidemia, height
Blood glucose, the disease such as fatty liver.Containing Rhizoma Polygonati Odorati total saponins and fragrant solomonseal rhizome polyoses in Rhizoma Polygonati Odorati, there is blood sugar lowering, defying age, quench one's thirst, anti-
Effect of tumor, also can repair islet function.The thick saponin of Radix Platycodonis contained in Radix Platycodonis has calmness, analgesia, refrigeration function, again
Energy blood sugar lowering, cholesterol reducing, relaxing smooth muscle.It is strong that Rhizoma Dioscoreae has nourishing, aid digestion, holds back sweating due to debility, effect of antidiarrheal,
Cure mainly insufficiency of the spleen diarrhoea, cough due to deficiency of the lung, diabetes are quenched one's thirst.Rhizoma Phragmitis energy heat clearing away, blood fat reducing, blood pressure lowering, to hypertension, hyperlipidemia,
The diseases such as arteriosclerosis, diabetes, obesity all have good curative effect.Rhizoma Polygonati is flat, sweet in the mouth, enters the heart, spleen, lung, kidney
Four warps, energy spleen reinforcing the lung moistening and production of body fluid promoting, there is good effect of lowering blood sugar.Herba Portulacae is nutritious, has enhancing myocardial function, prevents
Control heart disease, blood pressure lowering, blood sugar lowering, protection gastric mucosa, cosmetic slimming, effect of defying age.Rhizoma Dioscoreae contains batatasins,
There is the effect of blood sugar lowering, blood fat reducing.Containing N-sugar compounds in Rhizoma Phragmitis, there is the pharmacological action that suppression blood glucose rises, available
In preventing and treating and treatment diabetes.The harmful substances such as internal unnecessary fat, cholesterol can be excreted by Fructus Cannabis, Ji Nengpai
Poison fat-reducing, yin nourishing can nourish kidney liver again, be eaten for a long time, not only have chronic forms inflammation, constipation, hypertension and diabetes etc.
Significant curative effect, the benefit that also nourishes heart blood, the effect of life lengthening.Radix Glycyrrhizae contains treatment diabetes natural component, can help to drop blood
Sugar, antiinflammatory.The Radix Angelicae Dahuricae dispels the wind, dampness, detumescence, and pain relieving can control headache, supraorbital bone pain, toothache, nasal sinusitis, and cold-damp is suffered from abdominal pain,
And blood glucose can be reduced.Fructus Momordicae charantiae bitter in the mouth, sweet, salty, cold nature, enter liver, kidney, large intestine channel, loosening bowel to relieve constipation, blood fat reducing improving eyesight,
Treatment constipation and hyperlipidemia, diabetes, hypertension.Bulbus Lilii has nourishing the lung to arrest cough, mind tranquilizing and the heart calming, cancer-resisting, modern medicine
Pharmacological research confirms that Bulbus Lilii polysaccharide has obvious blood sugar reducing function.CitrusaurantiumL.Var.amara Engl. sweet in the mouth, micro-hardship, dispersing the stagnated liver-QI for regulating the stomach, resolving depression of regulating the flow of vital energy,
Cure mainly that painful abdominal mass in the heart is vexed, abdominal distention, vomiting are eaten less, and are had reduction blood glucose effect.Fructus Phyllanthi has blood sugar lowering and improves sugar
The sick complication effect of urine, flavonoid that its hypoglycemic activity may be contained with it and phytosterin compound, multiple organic acid and
Chromium, germanium, zinc, selenium and other trace elements are relevant.Fructus Citri Sarcodactylis has benefit think of of refreshing oneself, the improving eyesight that clears away heart-fire, diuresis removing toxic substances, fitness are prolonged life,
Blood sugar lowering, keep fit the health-care effecies such as body and mind.Fructus Hippophae contains multivitamin, fatty acid, trace element, sub-oil element, Fructus Hippophae
Flavone, superoxides isoreactivity material and the various aminoacid of needed by human body, can improve carbohydrate metabolism, have type 2 diabetes mellitus
Auxiliary therapeutic action.Japanese raisintree fruit sweet in the mouth, property are flat, nontoxic, have relieving restlessness of quenching the thirst, and go on diaphragm hot, moistening five ZANG-organs, profit defecation,
Diabetes are had auxiliary therapeutic action by the same Mel of merit.Lycium barbarum polysaccharide in Fructus Lycii is super in being remarkably reinforced damaged islet cells
The activity of superoxide dismutase (SOD), improves the oxidation resistance of islet cells, alleviates the peroxide damage to cell,
Dialdehyde growing amount in reducing, Fructus Lycii has certain protective effect to islet cells.Fructus Gardeniae have hepatoprotective, function of gallbladder promoting, blood pressure lowering,
Calm, stop blooding, the effect such as detumescence, be usually used in treating the diseases such as icterohepatitis, bruise, hypertension, diabetes.Fu
Lecithin contained by Siberian cocklebur and choline, can strengthen and improve cerebral function, and su-fuling diuresis effect is good, helps blood sugar lowering and fat-reducing.
Bulbus Allii Macrostemonis has effect that spleen invigorating is regulated the flow of vital energy, its contained Bulbus Allii Macrostemonis saponin A hypoglycemic, blood fat reducing, fat-reducing.Flos Sophorae bitter in the mouth, property is flat,
Nontoxic, there is effect of heat clearing away, removing heat from blood, hemostasis, blood pressure lowering, to haematemesis, hematuria, hypertension, hyperlipemia, blood vessel
Hardening, diabetes etc. have significant curative effect.Herba Cichorii is clearing away heat-damp and promoting diuresis, spleen invigorating medicine, can reduce blood glucose, blood fat, to diabetes
The Developmental and Metabolic Disorder caused and complication thereof have certain preventive and therapeutic effect.Flos Chrysanthemi induces sweat heat clearing away, and liver heat removing and eyesight improving can resist
Virus, it is also possible to blood sugar lowering, blood fat reducing.Above medicinal and edible plant blood sugar lowering determined curative effect, substantially without toxicity, side effect, tool
There is good health-care treatment.
Toothpaste is as requisite dental care products ordinary person's every day, and along with science and technology development, all kinds of toothpaste are come out one after another.
The purposes of toothpaste does not the most terminate in oral cavity cleaning, may also be combined with Chinese medicine and pharmacy, by scientific composition, reaches other health-care effecies.
During daily brushing teeth, active component contained in toothpaste can be through sublingual vein, oral cavity blood capillary and mucosa penetration, suction
Income blood, it is to avoid the first of active substance is closed elimination effect by the organs such as Liver and kidney, can reduce Liver and kidney burden simultaneously.Early, brush teeth evening
Become the custom of people, by the way of brushing teeth, absorbed active ingredient of Chinese herbs, there is the advantages such as side effect is little, be easily accepted by,
And can achieve many things at one stroke, get twice the result with half the effort.
Have Chinese medicine ingredients toothpaste at present and include that mica filled polypropylene, shiny pricklyash toothpaste etc., effect are mainly the pre-of oral disease
Prevent and treatment.Chinese patent literature CN103083212A discloses a kind of red sage root toothpaste, and prescription includes: Radix Salviae Miltiorrhizae extract,
Radix Codonopsis extract, Folium Ginkgo extract, Folium Nelumbinis extract, what Radix Platycodonis extract, Radix Angelicae Dahuricae extract etc..This prescription mostly is tool
Having the Chinese medicine ingredients of cardioprotection, its function of reducing blood sugar is more weak, and application has certain limitation.Chinese patent literature
CN101112376A discloses a kind of toothpaste for nursing cardiac and cerebral blood vessel with Rhizoma Phragmitis as main component.This toothpaste component is to the preventing and treating heart
Cerebrovascular disease has certain effect, but effective ingredient is single, and effect is limited.It is thus desirable to scientific composition, huge from China
In Chinese material medicine resource reasonably combined, develop effect more preferable and the most nontoxic there is blood sugar lowering, prevent and treat diabetic complication
The plant toothpaste with health therapy function.
Summary of the invention
The invention aims to solve existing have prevent and treat that the toothpaste purposes of diabetes effect is single, Chinese prescription hypoglycemic effect
More weak and long-term care treatment diabetes and the problem of complication thereof can not be reached, and a kind of medicine-food two-purpose blood sugar lowering toothpaste is provided
And preparation method thereof.
A kind of medicine-food two-purpose blood sugar lowering toothpaste of the present invention presses mass fraction by Fructus Momordicae charantiae extract 1%~10%, Rhizoma Polygonati Odorati extract
1%~5%, Radix Platycodonis extract 1%~5%, Rhizoma Dioscoreae extract 1%~5%, Rhizoma Phragmitis extract 1%~5%, enhancing phase extract
0%~6%, wetting agent 5%~60%, abrasivus 12%~60%, binding agent 0.5%~4%, foaming agent 1%~5.5%, perfume
Material 0%~2%, sweeting agent 0%~1%, food coloring 0%~1%, prepared by the deionized water of preservative 0%~0.5% and surplus
Form;
Described enhancing be mutually Rhizoma Polygonati, Herba Portulacae, Radix Puerariae, Folium Mori, Fructus Cannabis, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, Semen Cassiae, Bulbus Lilii,
CitrusaurantiumL.Var.amara Engl., Fructus Phyllanthi, Fructus Citri Sarcodactylis, Fructus Hippophae, Japanese raisintree fruit, Fructus Lycii, Fructus Gardeniae, Poria, Bulbus Allii Macrostemonis, Flos Sophorae, Herba Cichorii and Flos Chrysanthemi
In a kind of or any two kinds combination or the combination of any three kinds.
The preparation method of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present invention is frightened according to the following steps to be carried out:
One, by mass fraction weigh Fructus Momordicae charantiae extract 1%~10%, Rhizoma Polygonati Odorati extract 1%~5%, Radix Platycodonis extract 1%~5%,
Rhizoma Dioscoreae extract 1%~5%, Rhizoma Phragmitis extract 1%~5%, strengthen phase extract 0%~6%, wetting agent 5%~60%, rub
Liniment 12%~60%, binding agent 0.5%~4%, foaming agent 1%~5.5%, spice 0%~2%, sweeting agent 0%~1%, food
With pigment 0%~1%, preservative 0%~0.5% and the deionized water of surplus;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, vacuum be-0.09MPa~
Stir under conditions of-0.096MPa, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Beneficial effects of the present invention:
The main active ingredient of Fructus Momordicae charantiae selected by blood sugar reducing health raw material of toothpaste of the present invention is momordica saponins, Fructus Momordicae charantiae glucoside (polysaccharide), water-soluble
Acidic amino acid, flavonoid, multivitamin, trace element, mineral etc., have effect of eliminating inflammation and expelling toxin, eliminating phlegm and stopping cough,
Also can treat the diseases such as hypertension, hyperlipidemia, hyperglycemia, fatty liver.Containing Rhizoma Polygonati Odorati total saponins and fragrant solomonseal rhizome polyoses in Rhizoma Polygonati Odorati, tool
There are blood sugar lowering, defying age, quench one's thirst, effect of antitumor, also can repair islet function.The thick saponin of Radix Platycodonis contained in Radix Platycodonis
Have calmness, analgesia, a refrigeration function, again can blood sugar lowering, cholesterol reducing, relaxing smooth muscle.It is strong that Rhizoma Dioscoreae has nourishing, helps
Digestion, holds back sweating due to debility, effect of antidiarrheal, cures mainly insufficiency of the spleen diarrhoea, cough due to deficiency of the lung, diabetes are quenched one's thirst.Rhizoma Phragmitis energy heat clearing away, blood fat reducing,
Blood pressure lowering, all has good curative effect to diseases such as hypertension, hyperlipidemia, arteriosclerosis, diabetes, obesity.Above five kinds
Medicine food dual purpose plant is respectively provided with good blood sugar reducing health effect.
For increasing effect of above-mentioned plant formula, the also alternative Rhizoma Polygonati that adds of blood sugar reducing health toothpaste of the present invention, Herba Portulacae,
Rhizoma Dioscoreae, Rhizoma Phragmitis, Fructus Cannabis, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, Fructus Momordicae charantiae, Bulbus Lilii, CitrusaurantiumL.Var.amara Engl., Fructus Phyllanthi, Fructus Citri Sarcodactylis, Fructus Hippophae, Japanese raisintree fruit,
Fructus Lycii, Fructus Gardeniae, Poria, Bulbus Allii Macrostemonis, Flos Sophorae, Herba Cichorii, Flos Chrysanthemi.
Rhizoma Polygonati is flat, sweet in the mouth, enters the heart, spleen, lung, kidney four warp, energy spleen reinforcing the lung moistening and production of body fluid promoting, has good effect of lowering blood sugar.
Herba Portulacae is nutritious, has enhancing myocardial function, prevents and treats heart disease, blood pressure lowering, blood sugar lowering, protection gastric mucosa, beauty treatment
Fat-reducing, effect of defying age.Rhizoma Dioscoreae contains batatasins, has the effect of blood sugar lowering, blood fat reducing.Rhizoma Phragmitis closes containing N-saccharifying
Thing, has the pharmacological action that suppression blood glucose rises, can be used for preventing and treating and treating diabetes.Fructus Cannabis can be by internal unnecessary fat
The harmful substance such as fat, cholesterol excretes, and can lose weight by toxin expelling, yin nourishing can nourish kidney liver again, be eaten for a long time, the most right
Chronic forms inflammation, constipation, hypertension and diabetes etc. have significant curative effect, the benefit that also nourishes heart blood, the effect of life lengthening.Sweet
Grass, containing treatment diabetes natural component, can help blood sugar lowering, antiinflammatory.The Radix Angelicae Dahuricae dispels the wind, dampness, detumescence, and pain relieving can be controlled
Headache, supraorbital bone pain, toothache, nasal sinusitis, cold-damp is suffered from abdominal pain, and can be reduced blood glucose.Fructus Momordicae charantiae bitter in the mouth, sweet, salty, cold nature,
Enter liver, kidney, large intestine channel, loosening bowel to relieve constipation, blood fat reducing improving eyesight, treatment constipation and hyperlipidemia, diabetes, hypertension.Bulbus Lilii has
Nourishing the lung to arrest cough, mind tranquilizing and the heart calming, cancer-resisting, modern pharmacology research is had to confirm that Bulbus Lilii polysaccharide has obvious blood sugar reducing function.
CitrusaurantiumL.Var.amara Engl. sweet in the mouth, micro-hardship, dispersing the stagnated liver-QI for regulating the stomach, resolving depression of regulating the flow of vital energy, cure mainly that painful abdominal mass in the heart is vexed, abdominal distention, vomiting are eaten less, and had
Reduce blood glucose effect.Fructus Phyllanthi has blood sugar lowering and improves diabetic complication effect, its hypoglycemic activity may with its contained by
Flavonoid and phytosterin compound, multiple organic acid and chromium, germanium, zinc, selenium and other trace elements relevant.Fructus Citri Sarcodactylis has and carries
God's benefit think of, the improving eyesight that clears away heart-fire, diuresis removing toxic substances, fitness are prolonged life, blood sugar lowering, keep fit the health-care effecies such as body and mind.Fructus Hippophae contains multiple
Vitamin, fatty acid, trace element, sub-oil element, Fructus Hippophae flavone, superoxides isoreactivity material and needed by human body various
Aminoacid, can improve carbohydrate metabolism, type 2 diabetes mellitus is had auxiliary therapeutic action.Japanese raisintree fruit sweet in the mouth, property are flat, nontoxic, have
Quench the thirst relieving restlessness, remove heat on diaphragm, moistening five ZANG-organs, profit defecation, the same Mel of merit, diabetes are had auxiliary therapeutic action.Fructus Lycii
In lycium barbarum polysaccharide can be remarkably reinforced the activity of superoxide dismutase (SOD) in damaged islet cells, improve islet cells
Oxidation resistance, alleviates the peroxide damage to cell, and dialdehyde growing amount in reducing, islet cells is had necessarily by Fructus Lycii
Protective effect.Fructus Gardeniae have hepatoprotective, function of gallbladder promoting, blood pressure lowering, calmness, stop blooding, the effect such as detumescence, be usually used in treating icteric
The diseases such as hepatitis, bruise, hypertension, diabetes.Lecithin contained by Poria and choline, can strengthen and improve cerebral function,
Su-fuling diuresis effect is good, helps blood sugar lowering and fat-reducing.Bulbus Allii Macrostemonis has effect that spleen invigorating is regulated the flow of vital energy, its contained Bulbus Allii Macrostemonis saponin A
Hypoglycemic, blood fat reducing, fat-reducing.Flos Sophorae bitter in the mouth, property is put down, nontoxic, has effect of heat clearing away, removing heat from blood, hemostasis, blood pressure lowering, right
Haematemesis, hematuria, hypertension, hyperlipemia, sclerosis of blood vessels, diabetes etc. have significant curative effect.Herba Cichorii be clearing away heat-damp and promoting diuresis,
Spleen invigorating medicine, can reduce blood glucose, blood fat, and the Developmental and Metabolic Disorder causing diabetes and complication thereof have certain preventing
Control effect.Flos Chrysanthemi induces sweat heat clearing away, liver heat removing and eyesight improving, can antiviral, it is also possible to blood sugar lowering, blood fat reducing.Above medicine-food two-purpose is planted
Thing blood sugar lowering determined curative effect, substantially without toxicity, side effect, has good health-care treatment.Above medicine food dual purpose plant all has
There is good blood sugar reducing health effect.
The medicine food dual purpose plant active component Fructus Momordicae charantiae added in toothpaste of the present invention, Rhizoma Polygonati Odorati, Radix Platycodonis, Rhizoma Dioscoreae, Rhizoma Phragmitis, Rhizoma Polygonati,
Herba Portulacae, Rhizoma Dioscoreae, Rhizoma Phragmitis, Fructus Cannabis, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, Fructus Momordicae charantiae, Bulbus Lilii, CitrusaurantiumL.Var.amara Engl., Fructus Phyllanthi, Fructus Citri Sarcodactylis, Fructus Hippophae,
Japanese raisintree fruit, Fructus Lycii, Fructus Gardeniae, Poria, Bulbus Allii Macrostemonis, Flos Sophorae, Herba Cichorii, Flos Chrysanthemi, is according to Chinese medical theory scientific compatibility
Become, there is heat clearing and damp drying, reducing weight and blood fat, reducing pressure and sugar, reduction serum cholesterol, effect of triglyceride, also can remove
Halitosis, treatment dental bed swells and ache, words raw skin ulcer, toothache due to dental caries.By every day early, evening brush teeth, active component through sublingual vein,
Oral cavity blood capillary and mucosa penetration, absorbed into serum, it is to avoid the first of active ingredient of Chinese herbs is closed elimination effect by the organs such as Liver and kidney,
Liver and kidney burden can be alleviated simultaneously.This formula toothpaste and related oral care products, in addition to having traditional oral cavity cleaning effect, are lived
Property composition also can reduce blood glucose, blood fat, blood pressure, to diabetes and complication thereof, and cardiovascular and cerebrovascular vessel and metabolic disease tool
There is good health protection and therapeutic action.
Detailed description of the invention
Detailed description of the invention one: a kind of medicine-food two-purpose blood sugar lowering toothpaste of present embodiment presses mass fraction by Fructus Momordicae charantiae extract
1%~10%, Rhizoma Polygonati Odorati extract 1%~5%, Radix Platycodonis extract 1%~5%, Rhizoma Dioscoreae extract 1%~5%, Rhizoma Phragmitis extract
1%~5%, strengthen phase extract 0%~6%, wetting agent 5%~60%, abrasivus 12%~60%, binding agent 0.5%~4%,
Foaming agent 1%~5.5%, spice 0%~2%, sweeting agent 0%~1%, food coloring 0%~1%, preservative 0%~0.5% He
The deionized water of surplus is prepared from;
Described enhancing be mutually Rhizoma Polygonati, Herba Portulacae, Radix Puerariae, Folium Mori, Fructus Cannabis, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, Semen Cassiae, Bulbus Lilii,
CitrusaurantiumL.Var.amara Engl., Fructus Phyllanthi, Fructus Citri Sarcodactylis, Fructus Hippophae, Japanese raisintree fruit, Fructus Lycii, Fructus Gardeniae, Poria, Bulbus Allii Macrostemonis, Flos Sophorae, Herba Cichorii and Flos Chrysanthemi
In a kind of or any two kinds combination or the combination of any three kinds.
Detailed description of the invention two: present embodiment is unlike detailed description of the invention one: described a kind of medicine-food two-purpose blood sugar lowering
Toothpaste press mass fraction by Fructus Momordicae charantiae extract 8%, Rhizoma Polygonati Odorati extract 3%, Radix Platycodonis extract 3%, Rhizoma Dioscoreae extract 3%,
Rhizoma Phragmitis extract 3%, strengthen phase extract 6%, wetting agent 25%, abrasivus 35%, binding agent 1%, foaming agent 2%,
Spice 0.5%, sweeting agent 0.2%, food coloring 0.5%, the deionized water of preservative 0.3% and surplus is prepared from.Its
His step and parameter are identical with detailed description of the invention one.
Detailed description of the invention three: present embodiment is unlike detailed description of the invention one or two: described Fructus Momordicae charantiae extract
Preparation process is: is carried out Fructus Momordicae charantiae removing impurity, adds the deionized water of 8~16 times of Fructus Momordicae charantiae volumes after pulverizing, decocts
Boil 2 times, each 1 hour, merge after 2 times are decocted the extracting solution filtration of gained, merge, to after filtering, the extracting solution obtained
With activated carbon decolorizing, finally it is concentrated into the extractum that density is 1.10~1.30, obtains Fructus Momordicae charantiae extract;
The preparation process of described Rhizoma Polygonati Odorati extract is: be carried out Rhizoma Polygonati Odorati removing impurity, adds 8~16 times of jade after pulverizing
The deionized water of bamboo volume, decocts 2 times, each 1 hour, merges decoct the extracting solution filtration of gained by 2 times after, right
Merge the extracting solution activated carbon decolorizing obtained after filtration, be finally concentrated into the extractum that density is 1.10~1.30, obtain Rhizoma Polygonati Odorati
Extract;
The preparation process of described Radix Platycodonis extract is: be carried out Radix Platycodonis removing impurity, adds 8~16 times of Fructus Citri tangerinaes after pulverizing
The deionized water of stalk volume, decocts 2 times, each 1 hour, merges decoct the extracting solution filtration of gained by 2 times after, right
Merge the extracting solution activated carbon decolorizing obtained after filtration, be finally concentrated into the extractum that density is 1.10~1.30, obtain Radix Platycodonis
Extract;
The preparation process of described Rhizoma Dioscoreae extract is: be carried out Rhizoma Dioscoreae removing impurity, adds 8~16 times of mountains after pulverizing
The deionized water of medicine volume, decocts 2 times, each 1 hour, merges decoct the extracting solution filtration of gained by 2 times after, right
Merge the extracting solution activated carbon decolorizing obtained after filtration, be finally concentrated into the extractum that density is 1.10~1.30, obtain Rhizoma Dioscoreae
Extract;
The preparation process of described Rhizoma Phragmitis extract is: be carried out Rhizoma Phragmitis removing impurity, adds 8~16 times of reeds after pulverizing
The deionized water of root volume, decocts 2 times, each 1 hour, merges decoct the extracting solution filtration of gained by 2 times after, right
Merge the extracting solution activated carbon decolorizing obtained after filtration, be finally concentrated into the extractum that density is 1.10~1.30, obtain Rhizoma Phragmitis
Extract.Other steps and parameter are identical with detailed description of the invention one or two.
Detailed description of the invention four: present embodiment is unlike one of detailed description of the invention one to three: described Fructus Momordicae charantiae extracts
The preparation process of thing is: being carried out Fructus Momordicae charantiae removing impurity, the concentration adding 8~16 times of Fructus Momordicae charantiae volumes after pulverizing is 70%
Alcohol reflux 3 times, each 2 hours, 3 times are extracted after the extracting solution of gained filters and merge, merge after filtering
The extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.10~1.30, obtains Fructus Momordicae charantiae extract;
The preparation process of described Rhizoma Polygonati Odorati extract is: be carried out Rhizoma Polygonati Odorati removing impurity, adds 8~16 times of jade after pulverizing
The concentration of bamboo volume is the alcohol reflux 3 times of 70%, each 2 hours, extracts the extracting solution mistake of gained by 3 times
Merge after filter, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the leaching that density is 1.10~1.30
Cream, obtains Rhizoma Polygonati Odorati extract;
The preparation process of described Radix Platycodonis extract is: be carried out Radix Platycodonis removing impurity, adds 8~16 times of Fructus Citri tangerinaes after pulverizing
The alcohol reflux that concentration is 70% of stalk volume 3 times, each 2 hours, extracts the extracting solution mistake of gained by 3 times
Merge after filter, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the leaching that density is 1.10~1.30
Cream, obtains Radix Platycodonis extract;
The preparation process of described Rhizoma Dioscoreae extract is: be carried out Rhizoma Dioscoreae removing impurity, adds 8~16 times of mountains after pulverizing
The concentration of medicine volume is the alcohol reflux 3 times of 70%, each 2 hours, extracts the extracting solution mistake of gained by 3 times
Merge after filter, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the leaching that density is 1.10~1.30
Cream, obtains Rhizoma Dioscoreae extract;
The preparation process of described Rhizoma Phragmitis extract is: be carried out Rhizoma Phragmitis removing impurity, adds 8~16 times of reeds after pulverizing
The concentration of root volume is the alcohol reflux 3 times of 70%, each 2 hours, extracts the extracting solution mistake of gained by 3 times
Merge after filter, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the leaching that density is 1.10~1.30
Cream, obtains Rhizoma Phragmitis extract.Other steps and parameter are identical with one of detailed description of the invention one to three.
Detailed description of the invention five: present embodiment is unlike one of detailed description of the invention one to four: described enhancing carries mutually
The preparation process taking thing is: is carried out enhancing mutually removing impurity, carries out water and carry or alcohol extraction, merge after filtering after pulverizing
The extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.10~1.30, obtains strengthening phase extract.
Other steps and parameter are identical with one of detailed description of the invention one to four.
Detailed description of the invention six: present embodiment is unlike one of detailed description of the invention one to five: described water puies forward process
For: the enhancing after pulverizing is added to 8~16 times of deionized waters strengthening phase volume amounts, decocts 2 times, each 1 hour,
Merge after 2 times are decocted the extracting solution filtration of gained, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, the denseest
It is reduced to the extractum that density is 1.10~1.30.Other steps and parameter are identical with one of detailed description of the invention one to five.
Detailed description of the invention seven: present embodiment is unlike one of detailed description of the invention one to six: described alcohol extraction process
For: the enhancing after pulverizing is added to 8~16 times of alcohol reflux that concentration is 70% 3 times strengthening phase volume amounts, often
Secondary 2 hours, merge after 3 times are extracted the extracting solution filtration of gained, take off merging the extracting solution activated carbon obtained after filtering
Color, is finally concentrated into the extractum that density is 1.10~1.30.Other steps and parameter and one of detailed description of the invention one to six phase
With.
Detailed description of the invention eight: present embodiment is unlike one of detailed description of the invention one to seven: described wetting agent is
Glycerol, propylene glycol, glycerol, Polyethylene Glycol or sorbitol;Described abrasivus is calcium phosphate dibasic anhydrous, hydrogen phosphate dihydrate
Calcium, anhydride silica, anhydrous calcium pyrophosphate, calcium carbonate, clinochlore powder, calcite in powder or aluminium hydroxide;Described
Binding agent is sodium carboxymethyl cellulose, carbomer, carboxyethyl cellulose, hydroxypropyl melon glue, carrageenan, thickening type two
Silicon oxide, colloidality aluminium-magnesium silicate, sodium alginate or yellow natural gum powder.Other steps and parameter and detailed description of the invention one to seven it
One is identical.
Detailed description of the invention nine: present embodiment is unlike one of detailed description of the invention one to eight: described foaming agent is
Sodium lauryl sulphate, acyl glutamic acid sodium, sodium lauroyl sarcosine or methyl cocoa aliphatic radical sodium taurocholate;Described spice
For purple lemon sesame oil, orange oil, mandarin oil, Soviet Union's oil, Oleum Menthae Rotundifoliae, wintergreen oil, Radix Platycodonis oil, Oleum Cinnamomi, Oleum Anisi Stellati, thin
Lotus oil, Mentholum, Borneolum Syntheticum, lauryl aldehyde, citral, vanillin or pentyl acetate.Other steps and parameter be embodied as
One of mode one to eight is identical.
Detailed description of the invention ten: present embodiment is unlike one of detailed description of the invention one to nine: described sweeting agent is
Sucrose, saccharin, cyclamate, xylitol, stevioside, disodium glycyrrhizinate, tripotassium glycyrrhetate trisodium glycyrrhetinate alive;Described
Food coloring is purple, pink colour, blue or green;Described preservative is p-Hydroxybenzoate, sodium benzoate, Pyrusussuriensis
Acid potassium or sorbitol.Other steps and parameter are identical with one of detailed description of the invention one to nine.
Detailed description of the invention 11: a kind of medicine-food two-purpose blood sugar lowering toothpaste of present embodiment and preparation method thereof, it is characterised in that
The method sequentially includes the following steps:
One, by mass fraction weigh Fructus Momordicae charantiae extract 1%~10%, Rhizoma Polygonati Odorati extract 1%~5%, Radix Platycodonis extract 1%~5%,
Rhizoma Dioscoreae extract 1%~5%, Rhizoma Phragmitis extract 1%~5%, strengthen phase extract 0%~6%, wetting agent 5%~60%, rub
Liniment 12%~60%, binding agent 0.5%~4%, foaming agent 1%~5.5%, spice 0%~2%, sweeting agent 0%~1%, food
With pigment 0%~1%, preservative 0%~0.5% and the deionized water of surplus;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, vacuum be-0.09MPa~
Stir under conditions of-0.096MPa, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 1, a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment are carried by Fructus Momordicae charantiae extract 8%, Rhizoma Polygonati Odorati by mass fraction
Take thing 3%, Radix Platycodonis extract 3%, Rhizoma Dioscoreae extract 3%, Rhizoma Phragmitis extract 3%, Rhizoma Polygonati extract 3%, Herba portulacae carry
Take thing 3%, glycerol 25%, anhydride silica 35%, carrageenan 1%, sodium lauryl sulphate 2%, Oleum menthae 0.5%,
Xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 9.5% are prepared from.
The preparation process of described Fructus Momordicae charantiae extract is: be carried out Fructus Momordicae charantiae removing impurity, adds 12 times of Fructus Momordicae charantiaes after pulverizing
The deionized water of volume, decocts 2 times, each 1 hour, merges, to mistake decoct the extracting solution filtration of gained by 2 times after
Merge the extracting solution activated carbon decolorizing obtained after filter, be finally concentrated into the extractum that density is 1.20, obtain Fructus Momordicae charantiae extract.
The preparation process of described Rhizoma Polygonati Odorati extract is: be carried out Rhizoma Polygonati Odorati removing impurity, adds 12 times of Rhizoma Polygonati Odorati after pulverizing
The deionized water of volume, decocts 2 times, each 1 hour, merges, to mistake decoct the extracting solution filtration of gained by 2 times after
Merge the extracting solution activated carbon decolorizing obtained after filter, be finally concentrated into the extractum that density is 1.20, obtain Rhizoma Polygonati Odorati extract.
The preparation process of described Radix Platycodonis extract is: be carried out Radix Platycodonis removing impurity, adds 12 times of Radix Platycodoniss after pulverizing
The deionized water of volume, decocts 2 times, each 1 hour, merges, to mistake decoct the extracting solution filtration of gained by 2 times after
Merge the extracting solution activated carbon decolorizing obtained after filter, be finally concentrated into the extractum that density is 1.20, obtain Radix Platycodonis extract.
The preparation process of described Rhizoma Dioscoreae extract is: be carried out Rhizoma Dioscoreae removing impurity, adds 12 times of Rhizoma Dioscoreaes after pulverizing
The deionized water of volume, decocts 2 times, each 1 hour, merges, to mistake decoct the extracting solution filtration of gained by 2 times after
Merge the extracting solution activated carbon decolorizing obtained after filter, be finally concentrated into the extractum that density is 1.20, obtain Rhizoma Dioscoreae extract;
The preparation process of described Rhizoma Phragmitis extract is: be carried out Rhizoma Phragmitis removing impurity, adds 12 times of Rhizoma Phragmitiss after pulverizing
The deionized water of volume, decocts 2 times, each 1 hour, merges, to mistake decoct the extracting solution filtration of gained by 2 times after
Merge the extracting solution activated carbon decolorizing obtained after filter, be finally concentrated into the extractum that density is 1.20, obtain Rhizoma Phragmitis extract.
The preparation process of described enhancing phase extract is: is 1. carried out Herba portulacae removing impurity, carries out water and carry after pulverizing,
Merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20, obtain Herba portulacae
Extract;2. it is carried out Rhizoma Polygonati removing impurity, carries out water after pulverizing and carry, live to merging the extracting solution obtained after filtering
Property carbon decoloring, is finally concentrated into the extractum that density is 1.20, obtains Rhizoma Polygonati extract;
Water in the present embodiment puies forward process: Rhizoma Polygonati and Herba portulacae after pulverizing are separately added into 12 times of object accumulated amounts to be extracted
Deionized water, decoct 2 times, each 1 hour, 2 times decocted after the extracting solution of gained filters and merge, close after filtering
And the extracting solution activated carbon decolorizing obtained, finally it is concentrated into the extractum that density is 1.20.
The preparation method of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 8%, Rhizoma Polygonati Odorati extract 3%, Radix Platycodonis extract 3%, Rhizoma Dioscoreae extract are weighed by mass fraction
3%, Rhizoma Phragmitis extract 3%, Rhizoma Polygonati extract 3%, Herba portulacae extract 3%, glycerol 25%, anhydride silica 35%,
Carrageenan 1%, sodium lauryl sulphate 2%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, benzene
Sodium formate 0.3% and deionized water 9.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 2, the Fructus Momordicae charantiae extract 14% of the present embodiment, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae are extracted
Thing 1%, Rhizoma Phragmitis extract 1%, glycerol 30%, anhydride silica 35%, carrageenan 2%, sodium lauryl sulphate
2%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 11.5%
It is prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is same as in Example 1.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 14%, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae extraction are weighed by mass fraction
Thing 1%, Rhizoma Phragmitis extract 1%, glycerol 30%, anhydride silica 35%, carrageenan 2%, sodium lauryl sulphate
2%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 11.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 3, the Fructus Momordicae charantiae extract 15% of the present embodiment, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae are extracted
Thing 1%, Rhizoma Phragmitis extract 1%, Radix Puerariae extract 1%, Folium Mori extract 1%, glycerol 30%, anhydride silica 35%,
Carrageenan 1%, sodium lauryl sulphate 2.5%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, benzene
Sodium formate 0.3% and deionized water 9% are prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is same as in Example 1.
The preparation process of described enhancing phase extract is: is 1. carried out Radix Puerariae removing impurity, carries out water and carry after pulverizing,
Merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20, obtain Radix Puerariae and carry
Take thing;2. it is carried out Folium Mori removing impurity, carries out water after pulverizing and carry, to merging the extracting solution activity obtained after filtering
Carbon decoloring, is finally concentrated into the extractum that density is 1.20, obtains Folium Mori extract.
Water in the present embodiment puies forward process: Radix Puerariae and Folium Mori after pulverizing are separately added into 12 times of object accumulated amounts to be extracted
Deionized water, decocts 2 times, each 1 hour, merges, merge after filtering decoct the extracting solution filtration of gained by 2 times after
The extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.20.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 15%, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae extraction are weighed by mass fraction
Thing 1%, Rhizoma Phragmitis extract 1%, Radix Puerariae extract 1%, Folium Mori extract 1%, glycerol 30%, anhydride silica 35%,
Carrageenan 1%, sodium lauryl sulphate 2.5%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, benzene
Sodium formate 0.3% and deionized water 9%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 4, the Fructus Momordicae charantiae extract 12% of the present embodiment, Rhizoma Polygonati Odorati extract 2%, Radix Platycodonis extract 2%, Rhizoma Dioscoreae are extracted
Thing 2%, Rhizoma Phragmitis extract 2%, Herba Cichorii extract 1%, Fructus Cannabis extract 1%, glycerol 35%, anhydride silica
25%, carrageenan 2%, sodium lauryl sulphate 2%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%,
Sodium benzoate 0.3% and deionized water 12.5% are prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is same as in Example 1.
The preparation process of described enhancing phase extract is: is 1. carried out Herba Cichorii removing impurity, carries out water and carry after pulverizing,
Merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20, obtain Herba Cichorii and carry
Take thing;2. it is carried out Fructus Cannabis removing impurity, carries out water after pulverizing and carry, live to merging the extracting solution obtained after filtering
Property carbon decoloring, is finally concentrated into the extractum that density is 1.20, obtains Fructus Cannabis extract.
Water in the present embodiment puies forward process: Herba Cichorii and Fructus Cannabis after pulverizing are separately added into 12 times of object accumulated amounts to be extracted
Deionized water, decoct 2 times, each 1 hour, 2 times decocted after the extracting solution of gained filters and merge, close after filtering
And the extracting solution activated carbon decolorizing obtained, finally it is concentrated into the extractum that density is 1.20.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 12%, Rhizoma Polygonati Odorati extract 2%, Radix Platycodonis extract 2%, Rhizoma Dioscoreae extraction are weighed by mass fraction
Thing 2%, Rhizoma Phragmitis extract 2%, Herba Cichorii extract 1%, Fructus Cannabis extract 1%, glycerol 35%, anhydride silica
25%, carrageenan 2%, sodium lauryl sulphate 2%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%,
Sodium benzoate 0.3% and deionized water 12.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 5, the Fructus Momordicae charantiae extract 12% of the present embodiment, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae are extracted
Thing 1%, Rhizoma Phragmitis extract 1%, Radix Glycyrrhizae extract 1%, Radix Angelicae Dahuricae extract 1%, glycerol 35%, anhydride silica 30%,
Carrageenan 2%, sodium lauryl sulphate 2%, Oleum menthae 1.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, benzene
Sodium formate 0.3% and deionized water 10.5% are prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is same as in Example 1.
The preparation process of described enhancing phase extract is: is 1. carried out Radix Glycyrrhizae removing impurity, carries out water and carry after pulverizing,
Merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20, obtain Radix Glycyrrhizae and carry
Take thing;2. it is carried out the Radix Angelicae Dahuricae removing impurity, carries out water after pulverizing and carry, to merging the extracting solution activity obtained after filtering
Carbon decoloring, is finally concentrated into the extractum that density is 1.20, obtains Radix Angelicae Dahuricae extract.
Water in the present embodiment puies forward process: Radix Glycyrrhizae and the Radix Angelicae Dahuricae after pulverizing are separately added into 12 times of object accumulated amounts to be extracted
Deionized water, decocts 2 times, each 1 hour, merges, merge after filtering decoct the extracting solution filtration of gained by 2 times after
The extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.20.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 12%, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae extraction are weighed by mass fraction
Thing 1%, Rhizoma Phragmitis extract 1%, Radix Glycyrrhizae extract 1%, Radix Angelicae Dahuricae extract 1%, glycerol 35%, anhydride silica 30%,
Carrageenan 2%, sodium lauryl sulphate 2%, Oleum menthae 1.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, benzene
Sodium formate 0.3% and deionized water 10.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 6, the Fructus Momordicae charantiae extract 10% of the present embodiment, Rhizoma Polygonati Odorati extract 4%, Radix Platycodonis extract 4%, Rhizoma Dioscoreae are extracted
Thing 4%, Rhizoma Phragmitis extract 4%, Semen Cassiae extract 2%, Bulbus Lilii extract 2%, glycerol 40%, anhydride silica
20%, carrageenan 1%, sodium lauryl sulphate 1%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%,
Sodium benzoate 0.3% and deionized water 6.5% are prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is same as in Example 1.
The preparation process of described enhancing phase extract is: is 1. carried out Semen Cassiae removing impurity, carries out water and carry after pulverizing,
Merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20, obtain Semen Cassiae
Extract;2. it is carried out Bulbus Lilii removing impurity, carries out water after pulverizing and carry, live to merging the extracting solution obtained after filtering
Property carbon decoloring, is finally concentrated into the extractum that density is 1.20, obtains Bulbus Lilii extract.
Water in the present embodiment puies forward process: Semen Cassiae and Bulbus Lilii after pulverizing are separately added into 12 times of object accumulated amounts to be extracted
Deionized water, decoct 2 times, each 1 hour, 2 times decocted after the extracting solution of gained filters and merge, close after filtering
And the extracting solution activated carbon decolorizing obtained, finally it is concentrated into the extractum that density is 1.20.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 10%, Rhizoma Polygonati Odorati extract 4%, Radix Platycodonis extract 4%, Rhizoma Dioscoreae extraction are weighed by mass fraction
Thing 4%, Rhizoma Phragmitis extract 4%, Semen Cassiae extract 2%, Bulbus Lilii extract 2%, glycerol 40%, anhydride silica
20%, carrageenan 1%, sodium lauryl sulphate 1%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%,
Sodium benzoate 0.3% and deionized water 6.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 7, the Fructus Momordicae charantiae extract 10% of the present embodiment, Rhizoma Polygonati Odorati extract 2%, Radix Platycodonis extract 2%, Rhizoma Dioscoreae are extracted
Thing 2%, Rhizoma Phragmitis extract 2%, CitrusaurantiumL.Var.amara Engl. extract 1%, Fructus Phyllanthi extract 1%, glycerol 30%, anhydrous titanium dioxide
Silicon 35%, carrageenan 1.5%, sodium lauryl sulphate 2%, Oleum menthae 1%, xylitol 0.2%, non-polluted edible pigment
0.5%, sodium benzoate 0.3% and deionized water 9.5% are prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is same as in Example 1.
The preparation process of described enhancing phase extract is: is 1. carried out CitrusaurantiumL.Var.amara Engl. removing impurity, carries out water and carry after pulverizing,
Merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.10~1.30, obtain generation
Seville orange flower extract;2. it is carried out Fructus Phyllanthi removing impurity, carries out water after pulverizing and carry, merge, to after filtering, the extraction obtained
Liquid activated carbon decolorizing, is finally concentrated into the extractum that density is 1.10~1.30, obtains Fructus Phyllanthi extract.
Water in the present embodiment puies forward process: CitrusaurantiumL.Var.amara Engl. and Fructus Phyllanthi after pulverizing are separately added into 12 times of objects to be extracted and amass
The deionized water of amount, decocts 2 times, each 1 hour, merges, after filtering decoct the extracting solution filtration of gained by 2 times after
Merge the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 10%, Rhizoma Polygonati Odorati extract 2%, Radix Platycodonis extract 2%, Rhizoma Dioscoreae extraction are weighed by mass fraction
Thing 2%, Rhizoma Phragmitis extract 2%, CitrusaurantiumL.Var.amara Engl. extract 1%, Fructus Phyllanthi extract 1%, glycerol 30%, anhydrous titanium dioxide
Silicon 35%, carrageenan 1.5%, sodium lauryl sulphate 2%, Oleum menthae 1%, xylitol 0.2%, non-polluted edible pigment
0.5%, sodium benzoate 0.3% and deionized water 9.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 8, the Fructus Momordicae charantiae extract 8% of the present embodiment, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae are extracted
Thing 1%, Rhizoma Phragmitis extract 1%, Flos Sophorae extract 1%, Fructus Citri Sarcodactylis extract 1%, glycerol 30%, anhydride silica 40%,
Carrageenan 1%, sodium lauryl sulphate 2%, Oleum menthae 1%, xylitol 0.2%, non-polluted edible pigment 0.5%, benzene first
Acid sodium 0.3% and deionized water 11% are prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is same as in Example 1.
The preparation process of described enhancing phase extract is: is 1. carried out Flos Sophorae removing impurity, carries out water and carry after pulverizing,
Merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20, obtain Flos Sophorae and carry
Take thing;2. it is carried out Fructus Citri Sarcodactylis removing impurity, carries out water after pulverizing and carry, to merging the extracting solution activity obtained after filtering
Carbon decoloring, is finally concentrated into the extractum that density is 1.20, obtains Fructus Citri Sarcodactylis extract.
Water in the present embodiment puies forward process: Flos Sophorae and Fructus Citri Sarcodactylis after pulverizing are separately added into 12 times of object accumulated amounts to be extracted
Deionized water, decocts 2 times, each 1 hour, merges, merge after filtering decoct the extracting solution filtration of gained by 2 times after
The extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.20.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 8%, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae extract are weighed by mass fraction
1%, Rhizoma Phragmitis extract 1%, Flos Sophorae extract 1%, Fructus Citri Sarcodactylis extract 1%, glycerol 30%, anhydride silica 40%,
Carrageenan 1%, sodium lauryl sulphate 2%, Oleum menthae 1%, xylitol 0.2%, non-polluted edible pigment 0.5%, benzene first
Acid sodium 0.3% and deionized water 11%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 9, the Fructus Momordicae charantiae extract 8% of the present embodiment, Rhizoma Polygonati Odorati extract 2%, Radix Platycodonis extract 2%, Rhizoma Dioscoreae are extracted
Thing 2%, Rhizoma Phragmitis extract 2%, Fructus Hippophae extract 1%, Japanese raisintree fruit extract 1%, glycerol 30%, anhydride silica
35%, carrageenan 2%, sodium lauryl sulphate 2%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%,
Sodium benzoate 0.3% and deionized water 11.5% are prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is same as in Example 1.
The preparation process of described enhancing phase extract is: is 1. carried out Fructus Hippophae removing impurity, carries out water and carry after pulverizing,
Merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20, obtain Fructus Hippophae and carry
Take thing;2. it is carried out Japanese raisintree fruit removing impurity, carries out water after pulverizing and carry, live to merging the extracting solution obtained after filtering
Property carbon decoloring, is finally concentrated into the extractum that density is 1.20, obtains Japanese raisintree fruit extract.
Water in the present embodiment puies forward process: Fructus Hippophae and Japanese raisintree fruit after pulverizing are separately added into 12 times of object accumulated amounts to be extracted
Deionized water, decoct 2 times, each 1 hour, 2 times decocted after the extracting solution of gained filters and merge, close after filtering
And the extracting solution activated carbon decolorizing obtained, finally it is concentrated into the extractum that density is 1.20.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 8%, Rhizoma Polygonati Odorati extract 2%, Radix Platycodonis extract 2%, Rhizoma Dioscoreae extract are weighed by mass fraction
2%, Rhizoma Phragmitis extract 2%, Fructus Hippophae extract 1%, Japanese raisintree fruit extract 1%, glycerol 30%, anhydride silica 35%,
Carrageenan 2%, sodium lauryl sulphate 2%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, benzene
Sodium formate 0.3% and deionized water 11.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 10, the Fructus Momordicae charantiae extract 6% of the present embodiment, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae are extracted
Thing 1%, Rhizoma Phragmitis extract 1%, Fructus Lycii extract 1%, Poria extract 1%, glycerol 30%, anhydride silica
40%, carrageenan 1%, sodium lauryl sulphate 3%, Oleum menthae 1%, xylitol 0.2%, non-polluted edible pigment 0.5%,
Sodium benzoate 0.3% and deionized water 12% are prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is same as in Example 1.
The preparation process of described enhancing phase extract is: is 1. carried out Fructus Lycii removing impurity, carries out water and carry after pulverizing,
Merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20, obtain Fructus Lycii
Extract;2. it is carried out Poria removing impurity, carries out water after pulverizing and carry, live to merging the extracting solution obtained after filtering
Property carbon decoloring, is finally concentrated into the extractum that density is 1.20, obtains Poria extract.
Water in the present embodiment puies forward process: Fructus Lycii and Poria after pulverizing are separately added into 12 times of object accumulated amounts to be extracted
Deionized water, decoct 2 times, each 1 hour, 2 times decocted after the extracting solution of gained filters and merge, close after filtering
And the extracting solution activated carbon decolorizing obtained, finally it is concentrated into the extractum that density is 1.20.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 6%, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae extract are weighed by mass fraction
1%, Rhizoma Phragmitis extract 1%, Fructus Lycii extract 1%, Poria extract 1%, glycerol 30%, anhydride silica 40%,
Carrageenan 1%, sodium lauryl sulphate 3%, Oleum menthae 1%, xylitol 0.2%, non-polluted edible pigment 0.5%, benzene first
Acid sodium 0.3% and deionized water 12%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 11, the Fructus Momordicae charantiae extract 12% of the present embodiment, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae carry
Take thing 1%, Rhizoma Phragmitis extract 1%, glycerol 30%, anhydride silica 38%, carrageenan 2%, sodium lauryl sulphate
2%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 10.5%
It is prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is same as in Example 1.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 12%, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae extraction are weighed by mass fraction
Thing 1%, Rhizoma Phragmitis extract 1%, glycerol 30%, anhydride silica 38%, carrageenan 2%, sodium lauryl sulphate
2%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 10.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 12, the Fructus Momordicae charantiae extract 10% of the present embodiment, Rhizoma Polygonati Odorati extract 2%, Radix Platycodonis extract 2%, Rhizoma Dioscoreae carry
Take thing 2%, Rhizoma Phragmitis extract 2%, Fructus Cannabis extract 2%, Fructus Lycii extract 2%, glycerol 28%, anhydrous dioxy
SiClx 36%, carrageenan 2%, sodium lauryl sulphate 3%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment
0.5%, sodium benzoate 0.3% and deionized water 8.5% are prepared from.
The preparation process of described Fructus Momordicae charantiae extract is: be carried out Fructus Momordicae charantiae removing impurity, adds 12 times of Fructus Momordicae charantiaes after pulverizing
The concentration of volume is the alcohol reflux 3 times of 70%, each 2 hours, and the extracting solution extracting gained by 3 times filters
Rear merging, merges, to after filtering, the extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.20,
To Fructus Momordicae charantiae extract;
The preparation process of described Rhizoma Polygonati Odorati extract is: be carried out Rhizoma Polygonati Odorati removing impurity, adds 12 times of Rhizoma Polygonati Odorati after pulverizing
The concentration of volume is the alcohol reflux 3 times of 70%, each 2 hours, and the extracting solution extracting gained by 3 times filters
Rear merging, merges, to after filtering, the extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.20,
To Rhizoma Polygonati Odorati extract;
The preparation process of described Radix Platycodonis extract is: be carried out Radix Platycodonis removing impurity, adds 12 times of Radix Platycodoniss after pulverizing
The concentration of volume is the alcohol reflux 3 times of 70%, each 2 hours, and the extracting solution extracting gained by 3 times filters
Rear merging, merges, to after filtering, the extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.20,
To Radix Platycodonis extract;
The preparation process of described Rhizoma Dioscoreae extract is: be carried out Rhizoma Dioscoreae removing impurity, adds 12 times of Rhizoma Dioscoreaes after pulverizing
The concentration of volume is the alcohol reflux 3 times of 70%, each 2 hours, and the extracting solution extracting gained by 3 times filters
Rear merging, merges, to after filtering, the extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.20,
To Rhizoma Dioscoreae extract;
The preparation process of described Rhizoma Phragmitis extract is: be carried out Rhizoma Phragmitis removing impurity, adds 12 times of Rhizoma Phragmitiss after pulverizing
The concentration of volume is the alcohol reflux 3 times of 70%, each 2 hours, and the extracting solution extracting gained by 3 times filters
Rear merging, merges, to after filtering, the extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.20,
To Rhizoma Phragmitis extract.
The preparation process of described enhancing phase extract is: is 1. carried out Fructus Cannabis removing impurity, carries out alcohol extraction after pulverizing,
Merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20, obtain Fructus Cannabis
Extract;2. it is carried out Fructus Lycii removing impurity, after pulverizing, carries out alcohol extraction, use merging the extracting solution obtained after filtering
Activated carbon decolorizing, is finally concentrated into the extractum that density is 1.20, obtains Fructus Lycii extract.
Alcohol extraction process in the present embodiment is: Fructus Cannabis and Fructus Lycii after pulverizing are separately added into 12 times of objects to be extracted and amass
The alcohol reflux that concentration is 70% of amount 3 times, each 2 hours, closes extract the extracting solution filtration of gained by 3 times after
And, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 10%, Rhizoma Polygonati Odorati extract 2%, Radix Platycodonis extract 2%, Rhizoma Dioscoreae extraction are weighed by mass fraction
Thing 2%, Rhizoma Phragmitis extract 2%, Fructus Cannabis extract 2%, Fructus Lycii extract 2%, glycerol 28%, anhydrous titanium dioxide
Silicon 36%, carrageenan 2%, sodium lauryl sulphate 3%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment
0.5%, sodium benzoate 0.3% and deionized water 8.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 13, the Fructus Momordicae charantiae extract 10% of the present embodiment, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae carry
Take thing 1%, Rhizoma Phragmitis extract 1%, Fructus Hippophae extract 1%, glycerol 28%, anhydride silica 38%, carrageenan 2%,
Sodium lauryl sulphate 3%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% He
Deionized water 12.5% is prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is identical with embodiment 12.
The preparation process of described enhancing phase extract is: is carried out Fructus Hippophae removing impurity, carries out alcohol extraction after pulverizing, right
Merge the extracting solution activated carbon decolorizing obtained after filtration, be finally concentrated into the extractum that density is 1.20, obtain Fructus Hippophae and extract
Thing.
Alcohol extraction process in the present embodiment is: it is 70% that the Fructus Hippophae after pulverizing adds the concentration of 12 times of object accumulated amounts to be extracted
Alcohol reflux 3 times, each 2 hours, 3 times are extracted after the extracting solution of gained filters and merge, merge after filtering
The extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.20.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 10%, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae extraction are weighed by mass fraction
Thing 1%, Rhizoma Phragmitis extract 1%, Fructus Hippophae extract 1%, glycerol 28%, anhydride silica 38%, carrageenan 2%,
Sodium lauryl sulphate 3%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% He
Deionized water 12.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa's in vacuum
Under the conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 14, the Fructus Momordicae charantiae extract 8% of the present embodiment, Rhizoma Polygonati Odorati extract 8%, Radix Platycodonis extract 8%, Rhizoma Dioscoreae are extracted
Thing 8%, Rhizoma Phragmitis extract 8%, glycerol 32%, anhydride silica 42%, carrageenan 1%, sodium lauryl sulphate
3%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 8.5%
It is prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is identical with embodiment 12.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 8%, Rhizoma Polygonati Odorati extract 8%, Radix Platycodonis extract 8%, Rhizoma Dioscoreae extract are weighed by mass fraction
8%, Rhizoma Phragmitis extract 8%, glycerol 32%, anhydride silica 42%, carrageenan 1%, sodium lauryl sulphate 3%,
Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 8.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 15, the Fructus Momordicae charantiae extract 6% of the present embodiment, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae are extracted
Thing 1%, Rhizoma Phragmitis extract 1%, Fructus Gardeniae extract 1%, glycerol 31%, anhydride silica 41%, carrageenan 2%,
Sodium lauryl sulphate 3%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% He
Deionized water 10.5% is prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is identical with embodiment 12.
The preparation process of described enhancing phase extract is: is carried out Fructus Gardeniae removing impurity, carries out alcohol extraction after pulverizing, right
Merge the extracting solution activated carbon decolorizing obtained after filtration, be finally concentrated into the extractum that density is 1.20, obtain Fructus Gardeniae and extract
Thing.
Alcohol extraction process in the present embodiment is: it is 70% that the Fructus Gardeniae after pulverizing adds the concentration of 12 times of object accumulated amounts to be extracted
Alcohol reflux 3 times, each 2 hours, 3 times are extracted after the extracting solution of gained filters and merge, merge after filtering
The extracting solution activated carbon decolorizing obtained, is finally concentrated into the extractum that density is 1.20.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 6%, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae extract are weighed by mass fraction
1%, Rhizoma Phragmitis extract 1%, Fructus Gardeniae extract 1%, glycerol 31%, anhydride silica 41%, carrageenan 2%, ten
Sodium dialkyl sulfate 3%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and going
Ionized water 10.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 16, the Fructus Momordicae charantiae extract 5% of the present embodiment, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae are extracted
Thing 1%, Rhizoma Phragmitis extract 1%, CitrusaurantiumL.Var.amara Engl. extract 1%, Herba portulacae extract 1%, Radix Puerariae extract 1%, Folium Mori carry
Take thing 1%, Bulbus Allii Macrostemonis extract 1%, Fructus Cannabis extract 1%, Herba Cichorii extract 1%, Radix Angelicae Dahuricae extract 1%, Semen Cassiae
Extract 1%, Bulbus Lilii extract 1%, glycerol 30%, anhydride silica 38%, carrageenan 1.5%, dodecyl sulfur
Acid sodium 2.5%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water
10.5% is prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is identical with embodiment 12.
The preparation process of described enhancing phase extract is: is carried out enhancing mutually removing impurity, carries out alcohol extraction after pulverizing,
Merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.20, obtain strengthening phase
Extract.
Alcohol extraction process in the present embodiment is: the enhancing after pulverizing is separately added into the concentration of 12 times of object accumulated amounts to be extracted mutually
It is the alcohol reflux 3 times of 70%, each 2 hours, 3 times is extracted after the extracting solution of gained filters and merge, to mistake
Merge the extracting solution activated carbon decolorizing obtained after filter, be finally concentrated into the extractum that density is 1.20.
Enhancing in the present embodiment be mutually CitrusaurantiumL.Var.amara Engl., Herba portulacae, Radix Puerariae, Folium Mori, Bulbus Allii Macrostemonis, Fructus Cannabis, Herba Cichorii, the Radix Angelicae Dahuricae,
Semen Cassiae, Bulbus Lilii extract.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 5%, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae extract are weighed by mass fraction
1%, Rhizoma Phragmitis extract 1%, CitrusaurantiumL.Var.amara Engl. extract 1%, Herba portulacae extract 1%, Radix Puerariae extract 1%, Folium Mori extract
Thing 1%, Bulbus Allii Macrostemonis extract 1%, Fructus Cannabis extract 1%, Herba Cichorii extract 1%, Radix Angelicae Dahuricae extract 1%, Semen Cassiae carry
Take thing 1%, Bulbus Lilii extract 1%, glycerol 30%, anhydride silica 38%, carrageenan 1.5%, lauryl sulphate acid
Sodium 2.5%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 10.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 17, the Fructus Momordicae charantiae extract 5% of the present embodiment, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae are extracted
Thing 1%, Rhizoma Phragmitis extract 1%, glycerol 30%, anhydride silica 42%, carrageenan 2%, sodium lauryl sulphate
3%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 12.5%
It is prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is identical with embodiment 12.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 5%, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae extract are weighed by mass fraction
1%, Rhizoma Phragmitis extract 1%, glycerol 30%, anhydride silica 42%, carrageenan 2%, sodium lauryl sulphate 3%,
Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 12.5%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Embodiment 18, the Fructus Momordicae charantiae extract 4% of the present embodiment, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae are extracted
Thing 1%, Rhizoma Phragmitis extract 1%, glycerol 33%, anhydride silica 45%, carrageenan 2%, sodium lauryl sulphate
2.5%, Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 8%
It is prepared from.
The system of Fructus Momordicae charantiae extract, Rhizoma Polygonati Odorati extract, Radix Platycodonis extract, Rhizoma Dioscoreae extract and Rhizoma Phragmitis extract in the present embodiment
Standby process is identical with embodiment 12.
The preparation process of a kind of medicine-food two-purpose blood sugar lowering toothpaste of the present embodiment is:
One, Fructus Momordicae charantiae extract 4%, Rhizoma Polygonati Odorati extract 1%, Radix Platycodonis extract 1%, Rhizoma Dioscoreae extract are weighed by mass fraction
1%, Rhizoma Phragmitis extract 1%, glycerol 33%, anhydride silica 45%, carrageenan 2%, sodium lauryl sulphate 2.5%,
Oleum menthae 0.5%, xylitol 0.2%, non-polluted edible pigment 0.5%, sodium benzoate 0.3% and deionized water 8%;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, is-0.09MPa in vacuum
Under conditions of stir, obtain medicine-food two-purpose blood sugar lowering toothpaste.
Test one, study medicine-food two-purpose blood sugar lowering toothpaste of the present invention to diabetes and the cardiovascular and cerebrovascular disease complication that induced thereof
Health protection and therapeutic action.
Subjects: 30 example diabeticss carry out clinical observation, and record the information such as its age, medical history and the state of an illness.
Toothpaste using method is: the toothpaste of patient's embodiment 2 preparation is brushed teeth, and each 2g brushes teeth 2-5 minute.
The course for the treatment of: 60 days be a course for the treatment of, morning every day, evening respectively brush teeth once.
Detection uses the toothpaste of embodiment 2 preparation to brush teeth the fasting glucose after a course for the treatment of and level of postprandial blood sugar.
Test result indicate that and be shown in Table 1, after using this toothpaste one course for the treatment of, diabetes are substantially alleviated.Fasting blood glucose level by
8.40 ± 0.14mmol/L is down to 7.91 ± 0.13mmol/L (* p < 0.05).Level of postprandial blood sugar is by 13.54 ± 0.20
Mmol/L is down to 12.96 ± 0.21mmol/L (* p < 0.05).
Table 1
Test two, diabetic cardiovascular complications include that the microangiopathies on Heart and great blood vessel, cardiomyopathy, heart are certainly
Main neuropathy, is the primary cause of disease causing diabetics dead.Coronary heart disease is the primary macrovascular complication of diabetes,
Research display, the mortality risk of diabetics coronary heart disease is higher than non-glycosuria patient population 3~5 times.
In 30 example study subjects in test one, 25 examples are had to suffer from angina pectoris.With reference to " Angina
Evaluation criteria " heart strand symptom efficacy assessment standard be divided into effective, effective, invalid, increase the weight of 4 grades.To above-mentioned 25 example diabetes
The angina pectoris classification before and after toothpaste prepared by embodiment 2 uses is carried out with patient with angina pectoris.
Experimental result is shown in Table 2: after using this toothpaste one course for the treatment of, angina pectoris symptom substantially alleviates.Obvious effective rate reaches 84%, has
Efficiency reaches 16%, has no invalid or increases the weight of situation.
Table 2
From result above, blood sugar reducing health toothpaste of the present invention, there is good function of reducing blood sugar, diabetes are lured simultaneously
The cardio-cerebrovascular complication sent out has obvious functions of prevention and health care.
Claims (10)
1. a medicine-food two-purpose blood sugar lowering toothpaste, it is characterised in that a kind of medicine-food two-purpose blood sugar lowering toothpaste is extracted by Fructus Momordicae charantiae by mass fraction
Thing 1%~10%, Rhizoma Polygonati Odorati extract 1%~5%, Radix Platycodonis extract 1%~5%, Rhizoma Dioscoreae extract 1%~5%, Rhizoma Phragmitis extract
1%~5%, strengthen phase extract 0%~6%, wetting agent 5%~60%, abrasivus 12%~60%, binding agent 0.5%~4%,
Foaming agent 1%~5.5%, spice 0%~2%, sweeting agent 0%~1%, food coloring 0%~1%, preservative 0%~0.5% He
The deionized water of surplus is prepared from;
Described enhancing be mutually Rhizoma Polygonati, Herba Portulacae, Radix Puerariae, Folium Mori, Fructus Cannabis, Radix Glycyrrhizae, the Radix Angelicae Dahuricae, Semen Cassiae, Bulbus Lilii,
CitrusaurantiumL.Var.amara Engl., Fructus Phyllanthi, Fructus Citri Sarcodactylis, Fructus Hippophae, Japanese raisintree fruit, Fructus Lycii, Fructus Gardeniae, Poria, Bulbus Allii Macrostemonis, Flos Sophorae, Herba Cichorii and Flos Chrysanthemi
In a kind of or any two kinds combination or the combination of any three kinds.
A kind of medicine-food two-purpose blood sugar lowering toothpaste the most according to claim 1, it is characterised in that the system of described Fructus Momordicae charantiae extract
Standby process is: is carried out Fructus Momordicae charantiae removing impurity, adds the deionized water of 8~16 times of Fructus Momordicae charantiae volumes after pulverizing, decocts 2
Secondary, each 1 hour, merge after 2 times are decocted the extracting solution filtration of gained, live to merging the extracting solution obtained after filtering
Property carbon decoloring, is finally concentrated into the extractum that density is 1.10~1.30, obtains Fructus Momordicae charantiae extract;
The preparation process of described Rhizoma Polygonati Odorati extract is: be carried out Rhizoma Polygonati Odorati removing impurity, adds 8~16 times of Rhizoma Polygonati Odorati after pulverizing
The deionized water of volume, decocts 2 times, each 1 hour, merges, to mistake decoct the extracting solution filtration of gained by 2 times after
Merge the extracting solution activated carbon decolorizing obtained after filter, be finally concentrated into the extractum that density is 1.10~1.30, obtain Rhizoma Polygonati Odorati and extract
Thing;
The preparation process of described Radix Platycodonis extract is: be carried out Radix Platycodonis removing impurity, adds 8~16 times of Radix Platycodoniss after pulverizing
The deionized water of volume, decocts 2 times, each 1 hour, merges, to mistake decoct the extracting solution filtration of gained by 2 times after
Merge the extracting solution activated carbon decolorizing obtained after filter, be finally concentrated into the extractum that density is 1.10~1.30, obtain Radix Platycodonis extract
Thing;
The preparation process of described Rhizoma Dioscoreae extract is: be carried out Rhizoma Dioscoreae removing impurity, adds 8~16 times of Rhizoma Dioscoreaes after pulverizing
The deionized water of volume, decocts 2 times, each 1 hour, merges, to mistake decoct the extracting solution filtration of gained by 2 times after
Merge the extracting solution activated carbon decolorizing obtained after filter, be finally concentrated into the extractum that density is 1.10~1.30, obtain Rhizoma Dioscoreae and extract
Thing;
The preparation process of described Rhizoma Phragmitis extract is: be carried out Rhizoma Phragmitis removing impurity, adds 8~16 times of Rhizoma Phragmitiss after pulverizing
The deionized water of volume, decocts 2 times, each 1 hour, merges, to mistake decoct the extracting solution filtration of gained by 2 times after
Merge the extracting solution activated carbon decolorizing obtained after filter, be finally concentrated into the extractum that density is 1.10~1.30, obtain Rhizoma Phragmitis and extract
Thing.
A kind of medicine-food two-purpose blood sugar lowering toothpaste the most according to claim 1, it is characterised in that the system of described Fructus Momordicae charantiae extract
Standby process is: is carried out Fructus Momordicae charantiae removing impurity, adds the ethanol that concentration is 70% of 8~16 times of Fructus Momordicae charantiae volumes after pulverizing
Reflux, extract, 3 times, each 2 hours, merges extract the extracting solution filtration of gained by 3 times after, obtains merging after filtering
Extracting solution activated carbon decolorizing, is finally concentrated into the extractum that density is 1.10~1.30, obtains Fructus Momordicae charantiae extract;
The preparation process of described Rhizoma Polygonati Odorati extract is: be carried out Rhizoma Polygonati Odorati removing impurity, adds 8~16 times of Rhizoma Polygonati Odorati after pulverizing
The concentration of volume is the alcohol reflux 3 times of 70%, each 2 hours, extracts after the extracting solution of gained filters by 3 times
Merge, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.10~1.30,
To Rhizoma Polygonati Odorati extract;
The preparation process of described Radix Platycodonis extract is: be carried out Radix Platycodonis removing impurity, adds 8~16 times of Radix Platycodoniss after pulverizing
The concentration of volume is the alcohol reflux 3 times of 70%, each 2 hours, extracts after the extracting solution of gained filters by 3 times
Merge, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.10~1.30,
To Radix Platycodonis extract;
The preparation process of described Rhizoma Dioscoreae extract is: be carried out Rhizoma Dioscoreae removing impurity, adds 8~16 times of Rhizoma Dioscoreaes after pulverizing
The concentration of volume is the alcohol reflux 3 times of 70%, each 2 hours, extracts after the extracting solution of gained filters by 3 times
Merge, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.10~1.30,
To Rhizoma Dioscoreae extract;
The preparation process of described Rhizoma Phragmitis extract is: be carried out Rhizoma Phragmitis removing impurity, adds 8~16 times of Rhizoma Phragmitiss after pulverizing
The concentration of volume is the alcohol reflux 3 times of 70%, each 2 hours, extracts after the extracting solution of gained filters by 3 times
Merge, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into the extractum that density is 1.10~1.30,
To Rhizoma Phragmitis extract.
A kind of medicine-food two-purpose blood sugar lowering toothpaste the most according to claim 1, it is characterised in that described enhancing phase extract
Preparation process is: is carried out enhancing mutually removing impurity, carries out water and carry or alcohol extraction, obtain merging after filtering after pulverizing
Extracting solution activated carbon decolorizing, is finally concentrated into the extractum that density is 1.10~1.30, obtains strengthening phase extract.
A kind of medicine-food two-purpose blood sugar lowering toothpaste the most according to claim 5, it is characterised in that described water puies forward process and is: will
Enhancing after pulverizing is added to 8~16 times of deionized waters strengthening phase volume amount, decocts 2 times, each 1 hour, decocts 2 times
Merge after boiling the extracting solution filtration of gained, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, be finally concentrated into density
It is the extractum of 1.10~1.30.
A kind of medicine-food two-purpose blood sugar lowering toothpaste the most according to claim 5, it is characterised in that described alcohol extraction process is: will
Enhancing after pulverizing is added to 8~16 times of alcohol reflux that concentration is 70% 3 times strengthening phase volume amounts, each 2 hours,
Merge after 3 times are extracted the extracting solution filtration of gained, merge, to after filtering, the extracting solution activated carbon decolorizing obtained, the denseest
It is reduced to the extractum that density is 1.10~1.30.
A kind of medicine-food two-purpose blood sugar lowering toothpaste the most according to claim 1, it is characterised in that described wetting agent be glycerol,
Propylene glycol, glycerol, Polyethylene Glycol or sorbitol;Described abrasivus is calcium phosphate dibasic anhydrous, dicalcium phosphate dehydrate, nothing
Water silicon dioxide, anhydrous calcium pyrophosphate, calcium carbonate, clinochlore powder, calcite in powder or aluminium hydroxide;Described binding agent
For sodium carboxymethyl cellulose, carbomer, carboxyethyl cellulose, hydroxypropyl melon glue, carrageenan, thickening type silicon dioxide,
Colloidality aluminium-magnesium silicate, sodium alginate or yellow natural gum powder.
A kind of medicine-food two-purpose blood sugar lowering toothpaste the most according to claim 1, it is characterised in that described foaming agent is dodecane
Base sodium sulfate, acyl glutamic acid sodium, sodium lauroyl sarcosine or methyl cocoa aliphatic radical sodium taurocholate;Described spice is purple lemon
Lemon Oleum sesami, orange oil, mandarin oil, Soviet Union's oil, Oleum Menthae Rotundifoliae, wintergreen oil, Oleum Caryophylli, Oleum Cinnamomi, Oleum Anisi Stellati, Oleum menthae,
Mentholum, Borneolum Syntheticum, lauryl aldehyde, citral, vanillin or pentyl acetate.
A kind of medicine-food two-purpose blood sugar lowering toothpaste the most according to claim 1, it is characterised in that described sweeting agent be sucrose,
Saccharin, cyclamate, xylitol, stevioside, disodium glycyrrhizinate, tripotassium glycyrrhetate trisodium glycyrrhetinate alive;Described edible color
Element is purple, pink colour, blue or green;Described preservative be p-Hydroxybenzoate, sodium benzoate, potassium sorbate or
Sorbitol.
10. medicine-food two-purpose blood sugar lowering toothpaste and preparation method thereof, it is characterised in that the method sequentially includes the following steps:
One, by mass fraction weigh Fructus Momordicae charantiae extract 1%~10%, Rhizoma Polygonati Odorati extract 1%~5%, Radix Platycodonis extract 1%~5%,
Rhizoma Dioscoreae extract 1%~5%, Rhizoma Phragmitis extract 1%~5%, enhancing phase extract 0%~6%, wetting agent 5%~60%, friction
Agent 12%~60%, binding agent 0.5%~4%, foaming agent 1%~5.5%, spice 0%~2%, sweeting agent 0%~1%, edible
Pigment 0%~1%, preservative 0%~0.5% and the deionized water of surplus;
Two, raw material mix homogeneously step one weighed, is subsequently placed in vacuum Manufacturing medicine extract machine, vacuum be-0.09MPa~
Stir under conditions of-0.096MPa, obtain medicine-food two-purpose blood sugar lowering toothpaste.
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CN107854395A (en) * | 2017-11-27 | 2018-03-30 | 大连丹特生物技术有限公司 | One kind sleeps preceding toothpaste and preparation method thereof |
WO2018065479A1 (en) * | 2016-10-04 | 2018-04-12 | Full Spectrum Laboratories Ltd | Chicory products containing cannabinoids |
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CN1457762A (en) * | 2003-06-18 | 2003-11-26 | 贾润臣 | Toothpaste capable of reducing blood sugar, balancing blood lipid and regulating blood-pressure |
CN102113986A (en) * | 2011-03-01 | 2011-07-06 | 柳州两面针股份有限公司 | Toothpaste suitable for diabetes patients |
CN104337702A (en) * | 2013-08-05 | 2015-02-11 | 萧湘 | Mouth caring article suitable for patient with diabetes |
CN104740308A (en) * | 2015-04-23 | 2015-07-01 | 广西达庆生物科技有限公司 | Medical biological blood sugar level reducing oral liquid and preparation method thereof |
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CN1457762A (en) * | 2003-06-18 | 2003-11-26 | 贾润臣 | Toothpaste capable of reducing blood sugar, balancing blood lipid and regulating blood-pressure |
CN102113986A (en) * | 2011-03-01 | 2011-07-06 | 柳州两面针股份有限公司 | Toothpaste suitable for diabetes patients |
CN104337702A (en) * | 2013-08-05 | 2015-02-11 | 萧湘 | Mouth caring article suitable for patient with diabetes |
CN104740308A (en) * | 2015-04-23 | 2015-07-01 | 广西达庆生物科技有限公司 | Medical biological blood sugar level reducing oral liquid and preparation method thereof |
Cited By (2)
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WO2018065479A1 (en) * | 2016-10-04 | 2018-04-12 | Full Spectrum Laboratories Ltd | Chicory products containing cannabinoids |
CN107854395A (en) * | 2017-11-27 | 2018-03-30 | 大连丹特生物技术有限公司 | One kind sleeps preceding toothpaste and preparation method thereof |
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