CN105943979A - Traditional Chinese medicinal preparation for treating skin tinea and rashes and preparation method of traditional Chinese medicinal preparation - Google Patents
Traditional Chinese medicinal preparation for treating skin tinea and rashes and preparation method of traditional Chinese medicinal preparation Download PDFInfo
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- CN105943979A CN105943979A CN201610338370.5A CN201610338370A CN105943979A CN 105943979 A CN105943979 A CN 105943979A CN 201610338370 A CN201610338370 A CN 201610338370A CN 105943979 A CN105943979 A CN 105943979A
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Classifications
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Abstract
The invention provides a traditional Chinese medicinal preparation for treating skin tinea and rashes, and belongs to the technical field of application of traditional Chinese medicine. The traditional Chinese medicinal preparation is an externally-applied drug made from radix sophorae flavescentis, coptis chinensis, cortex phellodendri, artemisia apiacea, folium isatidis, honeysuckles, fructus forsythiae, fructus cnidii, fructus kochiae, cortex fraxini, cotex dictamni, cortex pseudolaricis, cortex lycii radicis, zanthoxylum bungeanum, selfheal, radix stemonae, gypsum, Chinese mahonia, glabrousleaf pittosporum seeds, raw rhubarb, hydnocarpus anthelmintica, alum, borneol and realgar. The traditional Chinese medicinal preparation has the advantages that the therapy principle of coordinating monarch, minister and assistant drugs is followed through reasonable compatibility of the herbs, and synergistic interaction is achieved; the traditional Chinese medicinal preparation has the effects of clearing away heat and toxic materials, promoting blood circulation, removing stasis, relieving swelling and pain, diminishing inflammation, relieving itching, removing necrotic tissues, promoting granulation and dispersing the internal heat, has good curative effect on skin itch, fester, desquamation and abnormity when being applied clinically, and particularly, has good effect on skin tinea, urticaria and eczema; cure rate can reach over 80%, price is low, simplicity, convenience and quick action are achieved, and toxic and side effect is avoided.
Description
Technical field
The invention belongs to technical field of Chinese medicines, particularly relate to a kind for the treatment of in tinea and erythra
Medicine preparation and preparation method thereof.
Background technology
Tinea refers mainly to the dermatophytosis of parent's keratoprotein, mainly includes trichophyton, little spore
Daughter bacteria belongs to and Epidermophyton, invades the skin of humans and animals, hair, deck, the sense caused
Dye is referred to as tinea, is called for short tinea.Tinea still presses site of pathological change name at present
Such as tinea capitis, tinea corporis, tinea cruris, the tinea manuum, tinea pedis etc., summer is multiple, and winter is rare.At present
The medicament categories for the treatment of tinea is a lot, and particularly Chinese herbal and crude drugs preparations, such as Patent No.
Patent of invention " a kind of medicine treating tinea and the preparation side thereof of CN201510889684.X
Method " disclose Fel Sus domestica, Realgar, Peppermint essential oil, Fructus Seu Herba Pubescentis extract, common fig leaf juice extraction
Thing and the Chinese medicine formula of white sugar；The patent of invention of Patent No. CN201510647532.9 is " a kind of
Skin tinea dipping " disclose the Fructus Kochiae, Radix Chloranthi Serrati, Fructus Cnidii, Herba Pelargonii Graveolentis, Radix Sophorae Flavescentis, Cortex Phellodendri,
Fructus Carpesii, Cortex Dictamni, Semen Hydnocarpi, Mirabilitum, Periostracum Cicadae, Radix Et Rhizoma Rhei, stone, Hydrargyri Oxydum Rubrum, Semen Armeniacae Amarum, withered
Vitriol, Rhizoma Anemones Altaicae, the formula of Nidus Vespae.
Erythra is a kind of dermatosis.From simple skin color change to skin surface protuberance or
Vesicle etc. is occurred to have the diversified form of expression.The feature of erythra is that large and small tablet is red, has
Time can itch, sometimes will not itch.Western medical treatment erythra many employings hormone medicine, instant effect, but
Easily the most repeatedly, and big to health side effect；And according to theory of Chinese medical science, for the morbidity machine of erythra
Reason, detoxifies as the rule for the treatment of with clearing heat and expelling damp, dryness-transformation, carries out dialectical composition of prescription, to reach specimen
The double purpose controlled.In prior art, such as the patent of invention of Patent No. CN201510199990.0
" a kind of Chinese medicine composition treating erythra " disclose Cortex Magnoliae Officinalis, the Rhizoma Pinelliae, the Fructus Kochiae, Cortex Moutan,
The Chinese medicine formula of Radix Saposhnikoviae, Rhizoma Atractylodis, Rhizoma Acori Graminei etc.；Sending out of Patent No. CN201510055187.X
Bright patent " a kind of treat the external application Chinese medicine that erythra is red and swollen " disclose Herba Violae, Zaocys,
Cortex Phellodendri, Flos Chrysanthemi Indici, Herba Equiseti Hiemalis, Caulis Lonicerae, Pericarpium Arecae, favus skin, Radix Glycyrrhizae Preparata, Pericarpium Granati,
The Chinese medicine formula of Fructus Atriplicis Sibiricae etc..
Research worker of the present invention to have heat-clearing and toxic substances removing, damp eliminating dryness-transformation, blood-cooling itch-relieving, strengthening the spleen and
Stomach, toxin expelling dissipating blood stasis, the medical material of itch-stopping bactericidal have carried out conscientious careful screening study, make every effort to sieve
Select the Chinese medicine preparation that can treat skin and erythra, and for medical material extraction process,
Concrete dosage form preparation method is also carried out the impact analysis of different factor, makes every effort to look for for extensive patients
To curative effect more preferably, effect extensively, therapeutic effect more preferably product.
Summary of the invention
For solving above-mentioned technical problem, the invention provides a kind for the treatment of in tinea and erythra
Medicine preparation and preparation method thereof.Concrete scheme is as follows:
A kind of Chinese medicine preparation treating tinea and erythra that the present invention provides, in this Chinese medicine preparation
Chinese medicine include the raw material of following weight portion: Radix Sophorae Flavescentis 20-50 part, Rhizoma Coptidis 10-25 part, Cortex Phellodendri 10-25
Part, Herba Artemisiae Annuae 20-50 part, Folium Isatidis 10-25 part, Flos Lonicerae 10-25 part, Fructus Forsythiae 10-25 part, Serpentis
Machine tool 10-30 part, Fructus Kochiae 10-30 part, Cortex Fraxini 10-30 part, favus skin 10-30 part, the soil rose of Sharon
Skin 10-30 part, Cortex Lycii 10-30 part, Pericarpium Zanthoxyli 10-30 part, XIAKUQIU 5-20 part, Radix Stemonae 10-30
Part, Gypsum Fibrosum 10-30 part, Mahonia fortunei (Lindl.) Fedde 10-30 part, mountain prop up 10-25 part, raw army 5-20 part, big
Wind 5-20 part, bright Gong 3～15 parts, Borneolum Syntheticum 3～15 parts, Realgar 3～15 parts.
Further, the Chinese medicine in this Chinese medicine preparation includes the raw material of following weight portion: Radix Sophorae Flavescentis
20-40 part, Rhizoma Coptidis 10-20 part, Cortex Phellodendri 10-20 part, Herba Artemisiae Annuae 20-40 part, Folium Isatidis 10-20 part,
Flos Lonicerae 10-20 part, Fructus Forsythiae 10-20 part, Fructus Cnidii 15-25 part, Fructus Kochiae 15-25 part, Cortex Fraxini
15-25 part, favus skin 15-25 part, Cortex Pseudolaricis 15-25 part, Cortex Lycii 15-25 part, Pericarpium Zanthoxyli 15-25
Part, XIAKUQIU 5-15 part, Radix Stemonae 15-25 part, Gypsum Fibrosum 15-25 part, Mahonia fortunei (Lindl.) Fedde 15-25 part,
15-25 part, raw army 5-15 part, Semen Hydnocarpi 5-15 part, bright Gong 3～10 parts, Borneolum Syntheticum 3～10 are propped up in mountain
Part, Realgar 3～10 parts.
Further, the Chinese medicine in this Chinese medicine preparation includes the raw material of following weight portion: Radix Sophorae Flavescentis 30
Part, Rhizoma Coptidis 15 parts, Cortex Phellodendri 15 parts, Herba Artemisiae Annuae 30 parts, Folium Isatidis 15 parts, Flos Lonicerae 15 parts, Fructus Forsythiae
15 parts, Fructus Cnidii 20 parts, the Fructus Kochiae 20 parts, Cortex Fraxini 20 parts, favus skin 20 parts, Cortex Pseudolaricis 20
Part, Cortex Lycii 20 parts, 15 parts of Pericarpium Zanthoxyli, XIAKUQIU 10 parts, the Radix Stemonae 20 parts, 20 parts of Gypsum Fibrosum, ten
Big contribution 20 parts, mountain prop up 15 parts, raw army 10 parts, Semen Hydnocarpi 10 parts, bright Gong 5 parts, Borneolum Syntheticum 5
Part, Realgar 5 parts.
Further, described Chinese medicine preparation is topical agent.
Meanwhile, present invention also offers kind of a preparation side for the Chinese medicine preparation treating tinea and erythra
Method, comprises the following steps:
1) by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae, Fructus Cnidii,
The Fructus Kochiae, Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, stone
Cream, Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi soak more than 10min；
2) proportionally above-mentioned raw materials is put into soil tank, and puts into 2～4 times of weight of above-mentioned raw materials
More than soak by water 30min；Then medicinal liquid it is filtrated to get；
3) proportionally bright Gong, Borneolum Syntheticum, Realgar are added into the liquid, i.e. obtain topical agent.
Meanwhile, present invention also offers the system of the Chinese medicine preparation of another kind for the treatment of tinea and erythra
Preparation Method, comprises the following steps:
1) by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae, Fructus Cnidii,
The Fructus Kochiae, Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, stone
Cream, Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi soak more than 10min；
2) proportionally by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae,
After the mixing of Fructus Cnidii, the Fructus Kochiae, use 50-80% ethanol ultrasonic extraction 20-40min, filter
To alcohol extract；
By Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, Gypsum Fibrosum,
Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi proportionally mix 5-8 times amount water boiling and extraction 2-3
Secondary, each 1-2h, it is filtrated to get alcohol extract；
3) alcohol extract is mixed with alcohol extract, 50～60 DEG C the most again ,-0.07MPa
Drying under reduced pressure, it is thus achieved that dry extract；
4) dry extract proportionally mixes with bright Gong, Borneolum Syntheticum, Realgar, obtains mixture；
Being subsequently adding 100～200% vaseline of mixture weight, adding water stirs makes ointment,
It is topical agent.
The beneficial effects of the present invention is: all medicine reasonable compatibilities that the present invention provides exercise the monarch and his subjects' assistant
Principle, Synergistic, have heat-clearing and toxic substances removing, blood circulation promoting and blood stasis dispelling, reducing swelling and alleviating pain, anti-inflammatory anti-itch,
Removing the necrotic tissue and promoting granulation, dissipate effect of removing toxic substances, treatment skin pruritus, fester, desquamation, peculiar even energy
Play good therapeutical effect, use this side treatment curative effect fine, especially in treatment clinically
Tinea, urticaria and eczema have good effect, its cure rate is attained by more than 85%,
Price is low, easy, curative effect is fast, have no side effect.
Detailed description of the invention
Technical scheme is described further below, but claimed scope is not limited to
In described.
Embodiment one: external medicinal liquid
A kind of Chinese medicine preparation treating tinea and erythra that the present embodiment provides, this Chinese medicine preparation
In Chinese medicine include following raw material: Radix Sophorae Flavescentis 20g, Rhizoma Coptidis 10g, Cortex Phellodendri 15g, Herba Artemisiae Annuae 20-50g,
Folium Isatidis 10g, Flos Lonicerae 15g, Fructus Forsythiae 15g, Fructus Cnidii 15g, Fructus Kochiae 10g, Cortex Fraxini 10g,
Favus skin 10g, Cortex Pseudolaricis 10g, Cortex Lycii 10g, Pericarpium Zanthoxyli 10g, XIAKUQIU 5g, Radix Stemonae 15g,
Gypsum Fibrosum 10g, Mahonia fortunei (Lindl.) Fedde 10g, mountain prop up 10g, raw army 10g, Semen Hydnocarpi 10g, bright Gong 3g,
Borneolum Syntheticum 3g, Realgar 3g.
Preparation method comprises the following steps:
1) by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae, Fructus Cnidii,
The Fructus Kochiae, Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, stone
Cream, Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi soak more than 10min；
2) proportionally above-mentioned raw materials is put into soil tank, and puts into 2～4 times of weight of above-mentioned raw materials
More than soak by water 30min；Then medicinal liquid it is filtrated to get；
3) proportionally bright Gong, Borneolum Syntheticum, Realgar are added into the liquid, i.e. obtain topical agent.
Embodiment two: external medicinal liquid
A kind of Chinese medicine preparation treating tinea and erythra that the present embodiment provides, this Chinese medicine preparation
In Chinese medicine include following raw material: Radix Sophorae Flavescentis 50g, Rhizoma Coptidis 25g, Cortex Phellodendri 25g, Herba Artemisiae Annuae 50g, big
Folium Isatidis 25g, Flos Lonicerae 25g, Fructus Forsythiae 25g, Fructus Cnidii 30g, Fructus Kochiae 30g, Cortex Fraxini 30g, white
Tinea skin 30g, Cortex Pseudolaricis 30g, Cortex Lycii 30g, Pericarpium Zanthoxyli 30g, XIAKUQIU 20g, Radix Stemonae 30g,
Gypsum Fibrosum 30g, Mahonia fortunei (Lindl.) Fedde 30g, mountain prop up 25g, raw army 20g, Semen Hydnocarpi 20g, bright Gong 15g,
Borneolum Syntheticum 15g, Realgar 15g.
Preparation method comprises the following steps:
1) by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae, Fructus Cnidii,
The Fructus Kochiae, Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, stone
Cream, Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi soak more than 10min；
2) proportionally above-mentioned raw materials is put into native tank, and put into 2 times of weight of above-mentioned raw materials
More than soak by water 30min；Then medicinal liquid it is filtrated to get；
3) proportionally bright Gong, Borneolum Syntheticum, Realgar are added into the liquid, i.e. obtain topical agent.
Embodiment three: externally-applied ointment
A kind of Chinese medicine preparation treating tinea and erythra that the present embodiment provides, this Chinese medicine preparation
In Chinese medicine include following raw material: Radix Sophorae Flavescentis 20g, Rhizoma Coptidis 10g, Cortex Phellodendri 10g, Herba Artemisiae Annuae 20g, big
Folium Isatidis 10g, Flos Lonicerae 10g, Fructus Forsythiae 10g, Fructus Cnidii 15g, Fructus Kochiae 15g, Cortex Fraxini 15g, white
Tinea skin 15g, Cortex Pseudolaricis 15g, Cortex Lycii 15g, Pericarpium Zanthoxyli 15g, XIAKUQIU 5g, Radix Stemonae 15g,
15g, raw army 5g, Semen Hydnocarpi 5g, bright Gong 3g, ice are propped up in Gypsum Fibrosum 15g, Mahonia fortunei (Lindl.) Fedde 15g, mountain
Sheet 3g, Realgar 3g.
Its preparation method comprises the following steps:
1) by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae, Fructus Cnidii,
The Fructus Kochiae, Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, stone
Cream, Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi soak more than 10min；
2) proportionally by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae,
After the mixing of Fructus Cnidii, the Fructus Kochiae, use 50% ethanol ultrasonic extraction 20min, be filtrated to get second
Alcohol lixiviating solution；
By Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, Gypsum Fibrosum,
Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi proportionally mix 5 times amount water boiling and extraction 2 times,
1h, is filtrated to get alcohol extract every time；
3) alcohol extract is mixed with alcohol extract, 50 DEG C the most again ,-0.07MPa subtracts
Press dry dry, it is thus achieved that dry extract；
4) dry extract proportionally mixes with bright Gong, Borneolum Syntheticum, Realgar, obtains mixture；
Being subsequently adding 100% vaseline of mixture weight, adding water stirs makes ointment, is
Topical agent.
Embodiment four: externally-applied ointment
A kind of Chinese medicine preparation treating tinea and erythra that the present embodiment provides, this Chinese medicine preparation
In Chinese medicine include following raw material: Radix Sophorae Flavescentis 40g, Rhizoma Coptidis 20g, Cortex Phellodendri 20g, Herba Artemisiae Annuae 40g, big
Folium Isatidis 20g, Flos Lonicerae 20g, Fructus Forsythiae 20g, Fructus Cnidii 25g, Fructus Kochiae 25g, Cortex Fraxini 25g, white
Tinea skin 25g, Cortex Pseudolaricis 25g, Cortex Lycii 25g, Pericarpium Zanthoxyli 25g, XIAKUQIU 15g, Radix Stemonae 25g,
Gypsum Fibrosum 25g, Mahonia fortunei (Lindl.) Fedde 25g, mountain prop up 25g, raw army 15g, Semen Hydnocarpi 15g, bright Gong 10g,
Borneolum Syntheticum 10g, Realgar 10g.
Its preparation method comprises the following steps:
1) by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae, Fructus Cnidii,
The Fructus Kochiae, Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, stone
Cream, Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi soak more than 10min；
2) proportionally by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae,
After the mixing of Fructus Cnidii, the Fructus Kochiae, use 80% ethanol ultrasonic extraction 40min, be filtrated to get second
Alcohol lixiviating solution；
By Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, Gypsum Fibrosum,
Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi proportionally mix 8 times amount water boiling and extraction 3 times,
2h, is filtrated to get alcohol extract every time；
3) alcohol extract is mixed with alcohol extract, 60 DEG C the most again ,-0.07MPa subtracts
Press dry dry, it is thus achieved that dry extract；
4) dry extract proportionally mixes with bright Gong, Borneolum Syntheticum, Realgar, obtains mixture；
Being subsequently adding 200% vaseline of mixture weight, adding water stirs makes ointment, is
Topical agent.
Embodiment five: externally-applied ointment
A kind of Chinese medicine preparation treating tinea and erythra that the present embodiment provides, this Chinese medicine preparation
In Chinese medicine include following raw material: Radix Sophorae Flavescentis 30g, Rhizoma Coptidis 15g, Cortex Phellodendri 15g, Herba Artemisiae Annuae 30g, big
Folium Isatidis 15g, Flos Lonicerae 15g, Fructus Forsythiae 15g, Fructus Cnidii 20g, Fructus Kochiae 20g, Cortex Fraxini 20g, white
Tinea skin 20g, Cortex Pseudolaricis 20g, Cortex Lycii 20g, Pericarpium Zanthoxyli 15g, XIAKUQIU 10g, Radix Stemonae 20g,
Gypsum Fibrosum 20g, Mahonia fortunei (Lindl.) Fedde 20g, mountain prop up 15g, raw army 10g, Semen Hydnocarpi 10g, bright Gong 5g,
Borneolum Syntheticum 5g, Realgar 5g.
Its preparation method comprises the following steps:
1) by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae, Fructus Cnidii,
The Fructus Kochiae, Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, stone
Cream, Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi soak more than 10min；
2) proportionally by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae,
After the mixing of Fructus Cnidii, the Fructus Kochiae, use 65% ethanol ultrasonic extraction 30min, be filtrated to get second
Alcohol lixiviating solution；
By Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, Gypsum Fibrosum,
Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi proportionally mix 5-8 times amount water boiling and extraction 3 times,
2h, is filtrated to get alcohol extract every time；
3) alcohol extract is mixed with alcohol extract, 55 DEG C the most again ,-0.07MPa subtracts
Press dry dry, it is thus achieved that dry extract；
4) dry extract proportionally mixes with bright Gong, Borneolum Syntheticum, Realgar, obtains mixture；
Being subsequently adding 150% vaseline of mixture weight, adding water stirs makes ointment, is
Topical agent.
Further, in order to prove the technique effect of the present invention, present specification additionally provide with
Lower tests below example:
Embodiment 1: clinical experiment
1.1 tinea treatments
Accept tinea patient 430 example, wherein male 220 example, women 210 example, age 9-60 altogether for medical treatment
Year.
Therapeutic Method: topical agent treatment above 200 example of the embodiment of the present invention 2 of the present invention；
Use topical agent treatment above 230 example of the embodiment of the present invention 5；Smear affected part, twice on the one,
It within 7 days, it is a course for the treatment of.
Curative effect judging standard:
Curing: clinical symptoms all disappears, illing skin recovers normal, within more than 1 year, does not recurs.
Therapeutic outcome: use the cure rate of the topical agent of embodiment 2 making to reach 88%, make
92% is reached, the topical agent pair of the present invention with the cure rate of the topical agent of embodiment 5 making
Common tinea all has good therapeutic effect, is difficult to recurrence.
1.2, skin rash treatment
Include erythra patient 350 example, wherein male 205 example, women 145 example, age 9-60 altogether
Year.
Therapeutic Method: topical agent treatment above 170 example of the embodiment of the present invention 2 of the present invention；
Use topical agent treatment above 180 example of the embodiment of the present invention 5；Smear affected part, twice on the one,
It within 7 days, it is a course for the treatment of.
Curative effect judging standard:
Curing: clinical symptoms all disappears, illing skin recovers normal, within more than 1 year, does not recurs.
Therapeutic outcome:: use the cure rate of the topical agent of embodiment 2 making to reach 90%, make
88% is reached, the topical agent pair of the present invention with the cure rate of the topical agent of embodiment 5 making
Common erythra all has good therapeutic effect, is difficult to recurrence.
Test example 2: type testing
2.1, land so-and-so, sex: female, the age: 22 years old, come me on October 10th, 2015
Clinic, is diagnosed as obstinate tinea, uses the topical agent of the present embodiment 2, the most each
Once, after one month, check recovers normal to film.
2.2, Feng so-and-so, sex: female, the age: 26 years old, whole body being dispersed in property erythema, periphery
Having white silver bits to come off pruritus, the scalp sufferings that come off are serious, once examine in attached institute of Medical University Of Chongqing
Controlling, be diagnosed as psoriasis, through the big treatment of Chongqing medical courses in general, Relapse rate is not felt any better, and patient takes
After Western medicine, face swells anasarca.After change the place of examination the ground such as Shanghai, Guangdong treatment all have no that the state of an illness is good
Turn.Carry out my clinic on October 14th, 2015, use the topical agent of the present embodiment 2,
Twice on the one, once, after two months, sb.'s illness took a favorable turn, symptom after three months for the most each film
All disappear.
2.3, Guo so-and-so, sex: man, the age: 60 years old, come me on October 18th, 2015 and examine
Gone to a doctor.The multiple erythema of cervical region, back, arm, waist, pruritus 9 months the most repeatedly,
Once the hospitalize of local hospital Hezhou, weak curative effect were arrived.Use the topical agent of the present embodiment 5,
Twice on the one, the most each film once, treats healing in about ten days.
2.4, Tang, sex: man, age: 41 years old, just come my clinic on February 3rd, 2016
Examining, stating humidity pruritus at scrotum has and oozes out weak yellow liquid 7 days, uses the external application of the present embodiment 5
Medicament, twice on the one, the most each film once, is cured after five days.
2.5, Liu so-and-so, sex: female, the age: 39 years old, come my clinic on February 12nd, 2016
Medical.State pudendum redness pruritus half a year repeatedly, take Western medicine, external wash liquid is even can only alleviate the state of an illness,
Using the topical agent of the present embodiment 5, twice on the one, the most each film once, is treated ten days,
Symptom occurs the most again.
Above example only in order to technical scheme to be described, is not intended to limit；Although
With reference to previous embodiment, the present invention is described in detail, those of ordinary skill in the art
It is understood that the technical scheme described in foregoing embodiments still can be modified by it,
Or wherein portion of techniques feature is carried out equivalent；And these amendments or replacement, not
The essence making appropriate technical solution departs from the spirit and scope of various embodiments of the present invention technical scheme.
Claims (6)
1. the Chinese medicine preparation treating tinea and erythra, it is characterised in that: this Chinese medicine system
Chinese medicine in agent includes the raw material of following weight portion: Radix Sophorae Flavescentis 20-50 part, Rhizoma Coptidis 10-25 part, Huang
Cypress 10-25 part, Herba Artemisiae Annuae 20-50 part, Folium Isatidis 10-25 part, Flos Lonicerae 10-25 part, Fructus Forsythiae 10-25
Part, Fructus Cnidii 10-30 part, Fructus Kochiae 10-30 part, Cortex Fraxini 10-30 part, favus skin 10-30 part,
Cortex Pseudolaricis 10-30 part, Cortex Lycii 10-30 part, Pericarpium Zanthoxyli 10-30 part, XIAKUQIU 5-20 part, the Radix Stemonae
10-25 part, raw army 5-20 are propped up in 10-30 part, Gypsum Fibrosum 10-30 part, Mahonia fortunei (Lindl.) Fedde 10-30 part, mountain
Part, Semen Hydnocarpi 5-20 part, bright Gong 3～15 parts, Borneolum Syntheticum 3～15 parts, Realgar 3～15 parts.
2. treatment tinea as claimed in claim 1 and the Chinese medicine preparation of erythra, its feature exists
The raw material of following weight portion is included: Radix Sophorae Flavescentis 20-40 part, Huang in: the Chinese medicine in this Chinese medicine preparation
Even 10-20 part, Cortex Phellodendri 10-20 part, Herba Artemisiae Annuae 20-40 part, Folium Isatidis 10-20 part, Flos Lonicerae 10-20
Part, Fructus Forsythiae 10-20 part, Fructus Cnidii 15-25 part, Fructus Kochiae 15-25 part, Cortex Fraxini 15-25 part,
Favus skin 15-25 part, Cortex Pseudolaricis 15-25 part, Cortex Lycii 15-25 part, Pericarpium Zanthoxyli 15-25 part, summer
15-25 is propped up on withered ball 5-15 part, Radix Stemonae 15-25 part, Gypsum Fibrosum 15-25 part, Mahonia fortunei (Lindl.) Fedde 15-25 part, mountain
Part, raw army 5-15 part, Semen Hydnocarpi 5-15 part, bright Gong 3～10 parts, Borneolum Syntheticum 3～10 parts, Realgar 3～10
Part.
3. treatment tinea as claimed in claim 1 or 2 and the Chinese medicine preparation of erythra, it is special
Levy and be: the Chinese medicine in this Chinese medicine preparation includes the raw material of following weight portion: be Radix Sophorae Flavescentis 30 parts, yellow
Even 15 parts, Cortex Phellodendri 15 parts, Herba Artemisiae Annuae 30 parts, Folium Isatidis 15 parts, Flos Lonicerae 15 parts, Fructus Forsythiae 15 parts,
Fructus Cnidii 20 parts, the Fructus Kochiae 20 parts, Cortex Fraxini 20 parts, favus skin 20 parts, Cortex Pseudolaricis 20 parts,
Cortex Lycii 20 parts, 15 parts of Pericarpium Zanthoxyli, XIAKUQIU 10 parts, the Radix Stemonae 20 parts, 20 parts of Gypsum Fibrosum, Mahonia fortunei (Lindl.) Fedde
20 parts, mountain prop up 15 parts, raw army 10 parts, Semen Hydnocarpi 10 parts, bright Gong 5 parts, Borneolum Syntheticum 5 parts, Realgar
5 parts.
4. treatment tinea as claimed in claim 1 and the Chinese medicine preparation of erythra, its feature exists
In: described Chinese medicine preparation is topical agent.
5. the system of the Chinese medicine preparation of the treatment tinea as described in Claims 1 to 4 and erythra
Preparation Method, it is characterised in that comprise the following steps:
1) by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae, Fructus Cnidii,
The Fructus Kochiae, Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, stone
Cream, Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi soak more than 10min；
2) proportionally above-mentioned raw materials is put into soil tank, and puts into 2～4 times of weight of above-mentioned raw materials
More than soak by water 30min；Then medicinal liquid it is filtrated to get；
3) proportionally bright Gong, Borneolum Syntheticum, Realgar are added into the liquid, i.e. obtain topical agent.
6. the system of the Chinese medicine preparation of the treatment tinea as described in Claims 1 to 4 and erythra
Preparation Method, it is characterised in that comprise the following steps:
1) by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae, Fructus Cnidii,
The Fructus Kochiae, Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, stone
Cream, Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi soak more than 10min；
2) proportionally by Radix Sophorae Flavescentis, Rhizoma Coptidis, Cortex Phellodendri, Herba Artemisiae Annuae, Folium Isatidis, Flos Lonicerae, Fructus Forsythiae,
After the mixing of Fructus Cnidii, the Fructus Kochiae, use 50-80% ethanol ultrasonic extraction 20-40min, filter
To alcohol extract；
By Cortex Fraxini, favus skin, Cortex Pseudolaricis, Cortex Lycii, Pericarpium Zanthoxyli, XIAKUQIU, the Radix Stemonae, Gypsum Fibrosum,
Mahonia fortunei (Lindl.) Fedde, mountain prop up, raw army, Semen Hydnocarpi proportionally mix 5-8 times amount water boiling and extraction 2-3
Secondary, each 1-2h, it is filtrated to get alcohol extract；
3) alcohol extract is mixed with alcohol extract, 50～60 DEG C the most again ,-0.07MPa
Drying under reduced pressure, it is thus achieved that dry extract；
4) dry extract proportionally mixes with bright Gong, Borneolum Syntheticum, Realgar, obtains mixture；
Being subsequently adding 100～200% vaseline of mixture weight, adding water stirs makes ointment,
It is topical agent.
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| Publication number | Priority date | Publication date | Assignee | Title |
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| CN114788847A (en) * | 2022-06-08 | 2022-07-26 | 山西省中医药研究院（山西省中医院） | Traditional Chinese medicine composition containing folium isatidis and application of traditional Chinese medicine composition in treatment of targeted drug-related rash |
Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101664526A (en) * | 2008-09-02 | 2010-03-10 | 陈瑞华 | External Chinese medicinal lotion |
| CN103386058A (en) * | 2013-07-02 | 2013-11-13 | 袁娟 | Medicament for treating tinea cruris and preparation method |
| CN105327228A (en) * | 2015-11-05 | 2016-02-17 | 马树华 | Liquid medicine for treating psoriasis on human body |
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Patent Citations (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN101664526A (en) * | 2008-09-02 | 2010-03-10 | 陈瑞华 | External Chinese medicinal lotion |
| CN103386058A (en) * | 2013-07-02 | 2013-11-13 | 袁娟 | Medicament for treating tinea cruris and preparation method |
| CN105327228A (en) * | 2015-11-05 | 2016-02-17 | 马树华 | Liquid medicine for treating psoriasis on human body |
Cited By (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CN114788847A (en) * | 2022-06-08 | 2022-07-26 | 山西省中医药研究院（山西省中医院） | Traditional Chinese medicine composition containing folium isatidis and application of traditional Chinese medicine composition in treatment of targeted drug-related rash |
| CN114788847B (en) * | 2022-06-08 | 2023-04-07 | 山西省中医药研究院（山西省中医院） | Traditional Chinese medicine composition containing folium isatidis and application of traditional Chinese medicine composition in treatment of targeted drug-related rash |
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