CN105942428A - 一种降血压的复配甜味剂 - Google Patents
一种降血压的复配甜味剂 Download PDFInfo
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Abstract
本发明公开了一种降血压的复配甜味剂,其原料按重量份包括:莱鲍迪苷A 60‑80份,木糖醇5‑7份,低聚果糖3‑5份,海藻糖4‑6份,麦芽糖醇5‑7份,中药提取物10‑20份;其中,中药提取物的原料包括:枸杞子、黄芪、人参、银杏叶、决明子、牛膝、泽泻、熟地、山药、茯苓、白术、灵芝草、陈皮、酸枣仁、甘草。本发明口感好,能通过协调扩张外周血管、抑制外周交感神经、阻断肾上腺素受体和利尿的作用,全面降压;并且能滋补肝肾,益气健脾,调节身体的机能,从本质上改善身体状况,标本兼治,达到很好的降血压效果,且无毒副作用。
Description
技术领域
本发明涉及甜味剂技术领域,尤其涉及一种降血压的复配甜味剂。
背景技术
甜味剂是食品工业和医疗保健中不可或缺的重要原料,然而占据甜味剂市场居多的人工合成甜味剂可能对人体有致癌、治病的副作用,因而已被许多国家限制使用,而蔗糖的过多食用则导致越来越多的高血压等疾病的发生。
高血压是一种发病率、致残率、死亡率较高的疾病。目前,治疗高血压需长期服药,而且降血压的化学合成药物大都存在作用时间短、毒副作用大、依赖性较强,治疗效果存在局限性等问题。因此需要提供一种新的甜味剂,既能改善口感,又能降低血压。
甜菊糖苷是一种从菊科草本植物甜叶菊的叶片中提取的一种纯天然、高甜度、低热值的食品添加剂。是继蔗糖、甜菜糖之后的第三类糖源,其甜度是蔗糖的200-300倍,但热量仅为蔗糖的1/300,可广泛运用于食品、饮料、酿酒、医药等几乎所有糖领域中。甜菊糖苷主要成分为甜菊苷和莱鲍迪苷A。莱鲍迪苷A在甜度、理化性质等方面优于其他甜菊糖苷,而且口感接近蔗糖,是蔗糖的极佳替代品;甜菊苷具有清热、利尿、降血压、降血糖调节味酸的功效,可以用来做甜味剂,但是具有后苦味。
发明内容
基于背景技术存在的技术问题,本发明提出了一种降血压的复配甜味剂,本发明口感好,能通过协调扩张外周血管、抑制外周交感神经、阻断肾上腺素受体和利尿的作用,全面降压;并且能滋补肝肾,益气健脾,调节身体的机能,从本质上改善身体状况,标本兼治,达到很好的降血压效果,且无毒副作用。
本发明提出的一种降血压的复配甜味剂,其原料按重量份包括:莱鲍迪苷A60-80份,甜菊苷10-20份,木糖醇5-7份,低聚果糖3-5份,海藻糖4-6份,麦芽糖醇5-7份,中药提取物10-20份;
其中,中药提取物的原料包括:枸杞子、黄芪、人参、银杏叶、决明子、牛膝、泽泻、熟地、山药、茯苓、白术、灵芝草、陈皮、酸枣仁、甘草。
枸杞子,别名为苟起子、甜菜子、杞子、红青椒、构蹄子、狗***等,为茄科植物宁夏枸杞的干燥成熟果实。味甘,性平;入肝、肾经。能滋补肝肾,益精明目。用于虚劳精亏,腰膝酸痛,眩晕耳鸣,内热消渴,血虚萎黄,目昏不明。枸杞子还具有增强机体免疫力,抗氧化,降血脂,降血糖的作用。
黄芪,别名为绵芪、绵黄芪、黄耆等,为豆科草本植物蒙古黄芪、膜荚黄芪的干燥根。味甘,性温;入肺、脾经。能补气固表,托疮生肌。主治体虚自汗,久泻,脱肛,子宫脱垂,慢性肾炎,体虚浮肿,慢性溃疡,疮口久不愈合。
人参,别名为棒锤、山参、园参、参叶、人衔、鬼盖、土精、神草等,为五加科植物人参的根。味甘、苦,性温;入肺、脾经。能补气,固脱,生津,安神,益智。用于气短喘促,心悸健忘,口渴多汗,食少无力,一切急慢性疾病及失血后引起的休克、虚脱。
银杏叶,别名为飞蛾叶、鸭脚子等,为银杏科植物银杏的干燥叶。味甘、苦、涩,性平;入心、肺经。能敛肺,平喘,活血化瘀,止痛。用于肺虚咳喘;冠心病,心绞痛,高血脂。银杏还能增强记忆力。
决明子,别名为马蹄决明、钝叶决明、假绿豆、草决明、羊明等,为决明或小决明的干燥成熟种子。味甘、苦,性凉;入肝、肾经。能清热明目,润肠通便。用于目赤涩痛,羞明多泪,头痛眩晕,目暗不明,大便秘结,高血压。
牛膝,别名为怀牛膝、牛髁膝、山苋菜、对节草、红牛膝、杜牛膝、土牛膝等,为苋科植物牛膝的根。味酸、苦,性平;入肝、肾经。能补肝肾,强筋骨,逐瘀通经,引血下行。用于腰膝酸痛,筋骨无力,经闭症瘕,肝阳眩晕。
泽泻,别名为水泽、如意花、车苦菜、天鹅蛋、天秃等,为泽泻科植物泽泻的块茎。味甘,性寒;入肾、膀胱经。能利水渗湿;泄热通淋。用于小便不利;热淋涩痛;水肿胀满;泄泻;痰饮眩晕;遗精。
熟地,别名为熟地黄等,为玄参科植物地黄的块根经加工炮制而成。通常以酒、砂仁或陈皮为辅料经反复蒸晒,至内外色黑油润,质地柔软粘腻。味甘,性温;入肝、肾经。能滋阴,补血。用于阴虚血少,腰膝痿弱,劳嗽骨蒸,遗精,崩漏,***,消渴,溲数,耳聋,目昏。
山药,别名为怀山药、淮山药、土薯、山薯、山芋、玉延等,为薯蓣科薯蓣属植物山药的根茎。味甘,性平;入脾、肺、肾经。能补脾养胃,生津益肺,补肾填精。用于脾虚食少,便溏久泻,肺虚喘咳,肾虚遗精,带下,尿频,虚热消渴。
茯苓,别名为茯苓个、茯苓皮、茯苓块、赤茯苓、白茯苓、茯菟、茯灵等,为多孔菌科真菌茯苓的干燥菌核。味甘、淡,性平;入心、肺、脾经。能利水渗湿,健脾宁心。用于水肿尿少,痰饮眩悸,脾虚食少,便溏泄泻,心神不安,惊悸失眠。
白术,别名为于术、冬术、浙术、种术、山蓟等,为菊科植物白术的干燥根茎。味甘、苦,性温;入胃、脾经。能补脾,益胃,燥湿,和中,安胎。用于脾胃气弱,不思饮食,倦怠少气,虚胀,泄泻,痰饮,水肿,黄疸,湿痹,小便不利,头晕,自汗,胎气不安。
灵芝草,别名为三秀、茵、芝等,为多孔菌科植物紫芝或赤芝的全株。味甘,性平;入心、脾、肺经。能益气健脾,养心安神,止咳平喘。用于虚劳羸弱,食欲不振,心悸怔忡,失眠健忘,肺虚咳喘;完心病心绞痛、高血压及高血脂症。
陈皮,别名为橘皮、贵老、红皮、黄橘皮、广橘皮、新会皮、柑皮、广陈皮等,为芸香科植物橘及其栽培变种的成熟果皮。味辛、苦,性温;入肺、脾经。能理气健脾,燥湿化痰。用于胸脘胀满,食少吐泻,咳嗽痰多。
酸枣仁,别名为山枣仁、山酸枣、枣仁、酸枣核等,为鼠李科植物酸枣的种子。味甘,性平;入心、胆、肝经。能养肝,宁心,安神,敛汗。用于虚烦不眠,惊悸怔忡,烦渴,虚汗。
甘草,别名为甜草根、红甘草、粉甘草、粉草、美草、蜜甘、蜜草、蕗草、国老、灵通、甜草、甜根子、棒草等,为双子叶植物豆科甘草,胀果甘草或光果甘草的根及根茎。味甘,性平;入胃、肺、脾经。能清热解毒,润肺止咳,调和诸药;炙甘草能补脾益气。用于咽喉肿痛,咳嗽,脾胃虚弱,胃、十二指肠溃疡,肝炎,癔病,痈疖肿毒,药物及食物中毒。
优选地,其原料按重量份包括:莱鲍迪苷A 65-75份,甜菊苷13-17份,木糖醇5.5-6.5份,低聚果糖3.5-4.5份,海藻糖4.5-5.5份,麦芽糖醇5.5-6.5份,中药提取物12-18份。
优选地,中药提取物的原料按重量份包括:枸杞子4-8份,黄芪4-6份,人参6-9份,银杏叶3-5份,决明子2-4份,牛膝3-5份,泽泻2-4份,熟地4-6份,山药6-9份,茯苓5-7份,白术2-4份,灵芝草3-4份,陈皮1-3份,酸枣仁1-2份,甘草4-6份。
优选地,在中药提取物的制备过程中,将枸杞子、黄芪、人参、银杏叶、决明子、牛膝、泽泻、熟地、山药、茯苓、白术、灵芝草、陈皮、酸枣仁、甘草粉碎混匀得到混合物;向混合物中加入水,升温,超声,过滤得到一次滤渣和一次滤液,取一次滤液用陶瓷膜过滤得到一次透过液,减压干燥得到物料A;将物料A纯化得到物料B;向一次滤渣中加入乙醇水溶液,升温,超声,过滤得到二次滤渣和二次滤液,取二次滤液用陶瓷膜过滤得到二次透过液,取二次透过液纯化,减压干燥得到物料C;向二次滤渣中加入乙醇,升温,超声,过滤得到三次滤渣和三次滤液,取三次滤液用陶瓷膜过滤得到三次透过液,减压干燥得到物料D;将物料D纯化得到物料E;将物料B、物料C、物料E粉碎混匀得到中药提取物。
优选地,在中药提取物的制备过程中,将枸杞子、黄芪、人参、银杏叶、决明子、牛膝、泽泻、熟地、山药、茯苓、白术、灵芝草、陈皮、酸枣仁、甘草粉碎混匀得到混合物;向混合物中加入水,升温至80-90℃,超声1-2h,过滤得到一次滤渣和一次滤液,取一次滤液用陶瓷膜过滤得到一次透过液,减压干燥得到物料A;将物料A溶于水中,加丙酮沉淀,过滤,将滤饼真空干燥得到物料B;向一次滤渣中加入质量分数为40-60wt%乙醇水溶液,升温至30-50℃,超声2-3h,过滤得到二次滤渣和二次滤液,取二次滤液用陶瓷膜过滤得到二次透过液,取二次透过液用超滤膜过滤得到超滤透过液,减压干燥得到物料C;向二次滤渣中加入乙醇,升温至30-50℃,超声40-60min,过滤得到三次滤渣和三次滤液,取三次滤液用陶瓷膜过滤得到三次透过液,减压干燥得到物料D;将物料D溶于乙醇中,加水沉淀,过滤,将滤饼真空干燥得到物料E;将物料B、物料C、物料E粉碎至100-300目混匀得到中药提取物。
优选地,在中药提取物的制备过程中,陶瓷膜的孔径为0.1-0.3μm。
优选地,在中药提取物的制备过程中,超滤膜的分子截留量为3000-4000D。
优选地,在中药提取物的制备过程中,在物料A中,混合物和水的重量比为1:20-30。
优选地,在中药提取物的制备过程中,在物料C中,混合物和乙醇水溶液的重量比为1:25-35。
优选地,在中药提取物的制备过程中,在物料D中,混合物和乙醇的重量比为1:15-25。
优选地,其原料按重量份包括:莱鲍迪苷A 70份,甜菊苷15份,木糖醇6份,低聚果糖4份,海藻糖5份,麦芽糖醇6份,中药提取物15份。
优选地,中药提取物的原料按重量份包括:枸杞子5-7份,黄芪4.5-5.5份,人参7-8份,银杏叶3.5-4.5份,决明子2.5-3.5份,牛膝3.5-4.5份,泽泻2.5-3.5份,熟地4.5-5.5份,山药7-8份,茯苓5.5-6.5份,白术2.5-3.5份,灵芝草3.3-3.7份,陈皮1.5-2.5份,酸枣仁1.3-1.7份,甘草4.5-5.5份。
优选地,中药提取物的原料按重量份包括:枸杞子6份,黄芪5份,人参7.5份,银杏叶4份,决明子3份,牛膝4份,泽泻3份,熟地5份,山药7.5份,茯苓6份,白术3份,灵芝草3.5份,陈皮2份,酸枣仁1.5份,甘草5份。
上述在中药提取物的制备过程中,在物料B中,水的作用是溶解,丙酮的作用是沉淀,不规定水和丙酮的用量,根据具体操作确定其用量。
上述在中药提取物的制备过程中,在物料E中,乙醇的作用是溶解,水的作用是沉淀,不规定乙醇和水的用量,根据具体操作确定其用量。
本发明选用的木糖醇具有防龋齿、不引起血糖波动,改善肠道功能,促进肠道益生菌的生长,改善肝功能等作用;低聚果糖既保持了蔗糖的纯正甜味性质,又比蔗糖甜味清爽,还具有调节肠道菌群,增殖双歧杆菌,促进钙的吸收,调节血脂,免疫调节,抗龋齿等保健功能的新型甜味剂;海藻糖对生物体具有神奇的保护作用,可以在高温、高寒、高渗透压及干燥失水等恶劣环境条件下在细胞表面能形成独特的保护膜,有效地保护蛋白质分子不变性失活,还具有防止食品劣化、保持食品新鲜风味、提升食品品质的作用;麦芽糖醇极难形成龋齿,能促进钙吸收、促进胰岛素分泌,抑制体内脂肪过多积累;莱鲍迪苷A、甜菊苷、木糖醇、低聚果糖、海藻糖、麦芽糖醇相互配合,可以改善甜菊苷的后苦味,改善本发明的口感,并能增加本发明的稳定性;枸杞子、黄芪、人参、银杏叶为君药,能在滋补肝肾、补气的同时,通过扩张外周血管、抑制外周交感神经、阻断肾上腺素受体,降低血压;决明子、牛膝、泽泻、熟地为臣药,能辅助君药进一步补肝肾,并且具有利尿的作用,可以配合君药的扩张外周血管、抑制外周交感神经、阻断肾上腺素受体的作用,达到很好的降压效果;山药、茯苓、白术、灵芝草为佐药,可以在辅助君药和臣药降压的同时,益气健脾、和胃、养心安神;陈皮、酸枣仁、甘草为使药,能理气、安神、调和诸药;上述诸药相互配合,扩张外周血管、抑制外周交感神经、阻断肾上腺素受体和利尿的作用,相互协调,可以全面降压;并且能滋补肝肾,益气健脾,调节身体的机能,从本质上改善身体状况,达到降压的作用,标本兼治,且无毒副作用;上述诸药可以和莱鲍迪苷A、甜菊苷相互配合,从而进一步增加本发明的降压效果;莱鲍迪苷A、甜菊苷、木糖醇、低聚果糖、海藻糖、麦芽糖醇与中药提取物相互配合,可以改善中药提取物造成的不良口感,保持本发明的口感。
具体实施方式
下面,通过具体实施例对本发明的技术方案进行详细说明。
实施例1
一种降血压的复配甜味剂,其原料按重量份包括:莱鲍迪苷A 70份,甜菊苷15份,木糖醇6份,低聚果糖4份,海藻糖5份,麦芽糖醇6份,中药提取物15份;
其中,中药提取物的原料包括:枸杞子、黄芪、人参、银杏叶、决明子、牛膝、泽泻、熟地、山药、茯苓、白术、灵芝草、陈皮、酸枣仁、甘草。
实施例2
一种降血压的复配甜味剂,其原料按重量份包括:莱鲍迪苷A 60份,甜菊苷20份,木糖醇5份,低聚果糖5份,海藻糖4份,麦芽糖醇7份,中药提取物10份;
其中,中药提取物的原料按重量份包括:枸杞子8份,黄芪4份,人参9份,银杏叶3份,决明子4份,牛膝3份,泽泻4份,熟地4份,山药9份,茯苓5份,白术4份,灵芝草3份,陈皮3份,酸枣仁1份,甘草6份。
实施例3
一种降血压的复配甜味剂,其原料按重量份包括:莱鲍迪苷A 80份,甜菊苷10份,木糖醇7份,低聚果糖3份,海藻糖6份,麦芽糖醇5份,中药提取物20份;
其中,中药提取物的原料按重量份包括:枸杞子4份,黄芪6份,人参6份,银杏叶5份,决明子2份,牛膝5份,泽泻2份,熟地6份,山药6份,茯苓7份,白术2份,灵芝草4份,陈皮1份,酸枣仁2份,甘草4份;
在中药提取物的制备过程中,将枸杞子、黄芪、人参、银杏叶、决明子、牛膝、泽泻、熟地、山药、茯苓、白术、灵芝草、陈皮、酸枣仁、甘草粉碎混匀得到混合物;向混合物中加入水,升温至90℃,超声1h,过滤得到一次滤渣和一次滤液,取一次滤液用孔径为0.3μm陶瓷膜过滤得到一次透过液,减压干燥得到物料A,其中,混合物和水的重量比为1:20;将物料A溶于水中,加丙酮沉淀,过滤,将滤饼真空干燥得到物料B;向一次滤渣中加入质量分数为60wt%乙醇水溶液,升温至30℃,超声3h,过滤得到二次滤渣和二次滤液,取二次滤液用孔径为0.1μm陶瓷膜过滤得到二次透过液,取二次透过液用分子截留量为4000D超滤膜过滤得到超滤透过液,减压干燥得到物料C,其中,混合物和乙醇水溶液的重量比为1:25;向二次滤渣中加入乙醇,升温至50℃,超声40min,过滤得到三次滤渣和三次滤液,取三次滤液用孔径为0.3μm陶瓷膜过滤得到三次透过液,减压干燥得到物料D,其中,混合物和乙醇的重量比为1:15;将物料D溶于乙醇中,加水沉淀,过滤,将滤饼真空干燥得到物料E;将物料B、物料C、物料E粉碎至300目混匀得到中药提取物。
实施例4
一种降血压的复配甜味剂,其原料按重量份包括:莱鲍迪苷A 65份,甜菊苷17份,木糖醇5.5份,低聚果糖4.5份,海藻糖4.5份,麦芽糖醇6.5份,中药提取物12份;
其中,中药提取物的原料按重量份包括:枸杞子7份,黄芪4.5份,人参8份,银杏叶3.5份,决明子3.5份,牛膝3.5份,泽泻3.5份,熟地4.5份,山药8份,茯苓5.5份,白术3.5份,灵芝草3.3份,陈皮2.5份,酸枣仁1.3份,甘草5.5份;
在中药提取物的制备过程中,将枸杞子、黄芪、人参、银杏叶、决明子、牛膝、泽泻、熟地、山药、茯苓、白术、灵芝草、陈皮、酸枣仁、甘草粉碎混匀得到混合物;向混合物中加入水,升温至80℃,超声2h,过滤得到一次滤渣和一次滤液,取一次滤液用孔径为0.1μm陶瓷膜过滤得到一次透过液,减压干燥得到物料A,其中,混合物和水的重量比为1:30;将物料A溶于水中,加丙酮沉淀,过滤,将滤饼真空干燥得到物料B;向一次滤渣中加入质量分数为40wt%乙醇水溶液,升温至50℃,超声2h,过滤得到二次滤渣和二次滤液,取二次滤液用孔径为0.3μm陶瓷膜过滤得到二次透过液,取二次透过液用分子截留量为3000D超滤膜过滤得到超滤透过液,减压干燥得到物料C,其中,混合物和乙醇水溶液的重量比为1:35;向二次滤渣中加入乙醇,升温至30℃,超声60min,过滤得到三次滤渣和三次滤液,取三次滤液用孔径为0.1μm陶瓷膜过滤得到三次透过液,减压干燥得到物料D,其中,混合物和乙醇的重量比为1:25;将物料D溶于乙醇中,加水沉淀,过滤,将滤饼真空干燥得到物料E;将物料B、物料C、物料E粉碎至100目混匀得到中药提取物。
实施例5
一种降血压的复配甜味剂,其原料按重量份包括:莱鲍迪苷A 75份,甜菊苷13份,木糖醇6.5份,低聚果糖3.5份,海藻糖5.5份,麦芽糖醇5.5份,中药提取物18份;
其中,中药提取物的原料按重量份包括:枸杞子5份,黄芪5.5份,人参7份,银杏叶4.5份,决明子2.5份,牛膝4.5份,泽泻2.5份,熟地5.5份,山药7份,茯苓6.5份,白术2.5份,灵芝草3.7份,陈皮1.5份,酸枣仁1.7份,甘草4.5份;
在中药提取物的制备过程中,将枸杞子、黄芪、人参、银杏叶、决明子、牛膝、泽泻、熟地、山药、茯苓、白术、灵芝草、陈皮、酸枣仁、甘草粉碎混匀得到混合物;向混合物中加入水,升温至85℃,超声1.5h,过滤得到一次滤渣和一次滤液,取一次滤液用孔径为0.2μm陶瓷膜过滤得到一次透过液,减压干燥得到物料A,其中,混合物和水的重量比为1:25;将物料A溶于水中,加丙酮沉淀,过滤,将滤饼真空干燥得到物料B;向一次滤渣中加入质量分数为50wt%乙醇水溶液,升温至40℃,超声2.5h,过滤得到二次滤渣和二次滤液,取二次滤液用孔径为0.2μm陶瓷膜过滤得到二次透过液,取二次透过液用分子截留量为3000D超滤膜过滤得到超滤透过液,减压干燥得到物料C,其中,混合物和乙醇水溶液的重量比为1:30;向二次滤渣中加入乙醇,升温至40℃,超声50min,过滤得到三次滤渣和三次滤液,取三次滤液用孔径为0.2μm陶瓷膜过滤得到三次透过液,减压干燥得到物料D,其中,混合物和乙醇的重量比为1:20;将物料D溶于乙醇中,加水沉淀,过滤,将滤饼真空干燥得到物料E;将物料B、物料C、物料E粉碎至200目混匀得到中药提取物。
试验例1
随机抽取经检查确定为高血压的患者100例,其中男53例,女47例,年龄48-63岁。将实施例5用水冲服,每8g为一剂,每天两剂,连续服用6个月。治疗结果为:在100例高血压患者中,痊愈79例,有效12例,无效9例,治愈率为79%,总有效率为91%,其中,临床症状全部消失,血压检查正常为痊愈;临床症状基本消失,舒张压和收缩压明显降低为有效;症状无明显改善为无效。
由上述结果可以看出,本发明降血压效果好。
以上所述,仅为本发明较佳的具体实施方式,但本发明的保护范围并不局限于此,任何熟悉本技术领域的技术人员在本发明揭露的技术范围内,根据本发明的技术方案及其发明构思加以等同替换或改变,都应涵盖在本发明的保护范围之内。
Claims (10)
1.一种降血压的复配甜味剂,其特征在于,其原料按重量份包括:莱鲍迪苷A 60-80份,甜菊苷10-20份,木糖醇5-7份,低聚果糖3-5份,海藻糖4-6份,麦芽糖醇5-7份,中药提取物10-20份;
其中,中药提取物的原料包括:枸杞子、黄芪、人参、银杏叶、决明子、牛膝、泽泻、熟地、山药、茯苓、白术、灵芝草、陈皮、酸枣仁、甘草。
2.根据权利要求1所述降血压的复配甜味剂,其特征在于,其原料按重量份包括:莱鲍迪苷A 65-75份,甜菊苷13-17份,木糖醇5.5-6.5份,低聚果糖3.5-4.5份,海藻糖4.5-5.5份,麦芽糖醇5.5-6.5份,中药提取物12-18份。
3.根据权利要求1或2所述降血压的复配甜味剂,其特征在于,中药提取物的原料按重量份包括:枸杞子4-8份,黄芪4-6份,人参6-9份,银杏叶3-5份,决明子2-4份,牛膝3-5份,泽泻2-4份,熟地4-6份,山药6-9份,茯苓5-7份,白术2-4份,灵芝草3-4份,陈皮1-3份,酸枣仁1-2份,甘草4-6份。
4.根据权利要求1-3任一项所述降血压的复配甜味剂,其特征在于,在中药提取物的制备过程中,将枸杞子、黄芪、人参、银杏叶、决明子、牛膝、泽泻、熟地、山药、茯苓、白术、灵芝草、陈皮、酸枣仁、甘草粉碎混匀得到混合物;向混合物中加入水,升温,超声,过滤得到一次滤渣和一次滤液,取一次滤液用陶瓷膜过滤得到一次透过液,减压干燥得到物料A;将物料A纯化得到物料B;向一次滤渣中加入乙醇水溶液,升温,超声,过滤得到二次滤渣和二次滤液,取二次滤液用陶瓷膜过滤得到二次透过液,取二次透过液纯化,减压干燥得到物料C;向二次滤渣中加入乙醇,升温,超声,过滤得到三次滤渣和三次滤液,取三次滤液用陶瓷膜过滤得到三次透过液,减压干燥得到物料D;将物料D纯化得到物料E;将物料B、物料C、物料E粉碎混匀得到中药提取物。
5.根据权利要求4所述降血压的复配甜味剂,其特征在于,在中药提取物的制备过程中,将枸杞子、黄芪、人参、银杏叶、决明子、牛膝、泽泻、熟地、山药、茯苓、白术、灵芝草、陈皮、酸枣仁、甘草粉碎混匀得到混合物;向混合物中加入水,升温至80-90℃,超声1-2h,过滤得到一次滤渣和一次滤液,取一次滤液用陶瓷膜过滤得到一次透过液,减压干燥得到物料A;将物料A溶于水中,加丙酮沉淀,过滤,将滤饼真空干燥得到物料B;向一次滤渣中加入质量分数为40-60wt%乙醇水溶液,升温至30-50℃,超声2-3h,过滤得到二次滤渣和二次滤液,取二次滤液用陶瓷膜过滤得到二次透过液,取二次透过液用超滤膜过滤得到超滤透过液,减压干燥得到物料C;向二次滤渣中加入乙醇,升温至30-50℃,超声40-60min,过滤得到三次滤渣和三次滤液,取三次滤液用陶瓷膜过滤得到三次透过液,减压干燥得到物料D;将物料D溶于乙醇中,加水沉淀,过滤,将滤饼真空干燥得到物料E;将物料B、物料C、物料E粉碎至100-300目混匀得到中药提取物。
6.根据权利要求4所述降血压的复配甜味剂,其特征在于,在中药提取物的制备过程中,陶瓷膜的孔径为0.1-0.3μm。
7.根据权利要求4所述降血压的复配甜味剂,其特征在于,在中药提取物的制备过程中,超滤膜的分子截留量为3000-4000D。
8.根据权利要求4所述降血压的复配甜味剂,其特征在于,在中药提取物的制备过程中,在物料A中,混合物和水的重量比为1:20-30。
9.根据权利要求4所述降血压的复配甜味剂,其特征在于,在中药提取物的制备过程中,在物料C中,混合物和乙醇水溶液的重量比为1:25-35。
10.根据权利要求4所述降血压的复配甜味剂,其特征在于,在中药提取物的制备过程中,在物料D中,混合物和乙醇的重量比为1:15-25。
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