CN105919559A - Tumor impedance and blood pressure monitoring device based on abdominal aorta stent and method based on tumor impedance and blood pressure monitoring device - Google Patents

Tumor impedance and blood pressure monitoring device based on abdominal aorta stent and method based on tumor impedance and blood pressure monitoring device Download PDF

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Publication number
CN105919559A
CN105919559A CN201610394051.6A CN201610394051A CN105919559A CN 105919559 A CN105919559 A CN 105919559A CN 201610394051 A CN201610394051 A CN 201610394051A CN 105919559 A CN105919559 A CN 105919559A
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impedance
integrated circuit
monitoring device
blood pressure
signal
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CN201610394051.6A
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Inventor
任勇
王景璟
李�灿
孟越
马骏
吴巍巍
史清宇
刘磊
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Priority to CN201610394051.6A priority Critical patent/CN105919559A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/0002Remote monitoring of patients using telemetry, e.g. transmission of vital signals via a communication network
    • A61B5/0031Implanted circuitry
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/02007Evaluating blood vessel condition, e.g. elasticity, compliance
    • A61B5/02014Determining aneurysm
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/02Detecting, measuring or recording pulse, heart rate, blood pressure or blood flow; Combined pulse/heart-rate/blood pressure determination; Evaluating a cardiovascular condition not otherwise provided for, e.g. using combinations of techniques provided for in this group with electrocardiography or electroauscultation; Heart catheters for measuring blood pressure
    • A61B5/021Measuring pressure in heart or blood vessels
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61BDIAGNOSIS; SURGERY; IDENTIFICATION
    • A61B5/00Measuring for diagnostic purposes; Identification of persons
    • A61B5/05Detecting, measuring or recording for diagnosis by means of electric currents or magnetic fields; Measuring using microwaves or radio waves 
    • A61B5/053Measuring electrical impedance or conductance of a portion of the body
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61FFILTERS IMPLANTABLE INTO BLOOD VESSELS; PROSTHESES; DEVICES PROVIDING PATENCY TO, OR PREVENTING COLLAPSING OF, TUBULAR STRUCTURES OF THE BODY, e.g. STENTS; ORTHOPAEDIC, NURSING OR CONTRACEPTIVE DEVICES; FOMENTATION; TREATMENT OR PROTECTION OF EYES OR EARS; BANDAGES, DRESSINGS OR ABSORBENT PADS; FIRST-AID KITS
    • A61F2/00Filters implantable into blood vessels; Prostheses, i.e. artificial substitutes or replacements for parts of the body; Appliances for connecting them with the body; Devices providing patency to, or preventing collapsing of, tubular structures of the body, e.g. stents
    • A61F2/02Prostheses implantable into the body
    • A61F2/04Hollow or tubular parts of organs, e.g. bladders, tracheae, bronchi or bile ducts
    • A61F2/06Blood vessels
    • A61F2/07Stent-grafts

Abstract

The invention relates to a tumor impedance and blood pressure monitoring device based on an abdominal aorta stent and a method based on the tumor impedance and blood pressure monitoring device. The tumor impedance and blood pressure monitoring device based on the abdominal aorta stent comprises a covered stent, an integrated circuit and external processing equipment, wherein the integrated circuit is arranged outside the covered stent and comprises an energy supply module, an impedance measurement sensor, a blood pressure sensor, a storage device, a data processor and a first radio frequency transceiving module; the energy supply module is used for supplying electric power to the integrated circuit; the impedance measurement sensor and the blood pressure sensor transmit detected impedance signals and blood vessel wall pressure signals to the data processor through the storage device, the data processor converts the impedance signals and the blood vessel wall pressure signals into digital signals and loads the integrated circuit ID and timestamp information, the first radio frequency transceiving module transmits the digital signals to the external processing equipment through the covered stent, and functions of data measurement and signal emission are realized accordingly. The tumor impedance and blood pressure monitoring device is small in size and produces low radiation, can monitor a patient in real time and can be widely applied to condition monitoring of abdominal aortic aneurysm.

Description

Tumor body impedance based on ventral aorta support and blood pressure monitoring device and method thereof
Technical field
The present invention relates to a kind of tumor body impedance and blood vessel wall pressure monitoring device and method thereof, especially with regard to one doctor Treat the tumor body impedance based on ventral aorta support and blood pressure monitoring device and method thereof applied in detection technique field.
Background technology
Along with aged tendency of population and the increase of the risk factor such as hypertension, arteriosclerosis, China's formation of abdominal aortic aneurysms Rate is obvious ascendant trend, and over-65s old people's formation of abdominal aortic aneurysms rate is up to 8.8%.Research shows, the most often 100000 people there are 20 people suffer from abdominal aortic aneurysm to 40 people.The ventral aorta of abnormal expansion is referred to as abdominal aortic aneurysm, it Although not being true neoplasm, but the harm to human body is the biggest, and tumor body ruptures and may result in death.Abdominal aortic aneurysm Formation is a progressive process, this progressive during, hereditism, environmentology and biochemistry factors phase Affect mutually, jointly act on, such as, change the metabolism of abdominal aorta wall elastic force connection tissue thus inspired ventral aorta The formation of tumor.
Interventional therapy becomes the modus operandi that abdominal aortic aneurysm is main at present.Support is imported aorta by this operation And it discharged in conduit, thus prevent aneurysm rupture.Due to the danger of abdominal aortic aneurysm, to ventral aorta Tumor carries out detecting particularly significant.At present, the inspection method of abdominal aortic aneurysm mainly includes color doppler ultrasonography, CTA And MRI etc..These methods above-mentioned are required for carrying out auxiliary detection by bigger equipment, can only carry out in hospital. And detect by these modes, all human body can be had than more serious radiation.
Summary of the invention
For the problems referred to above, it is an object of the invention to provide a kind of volume little, radiate little, patient can be carried out simultaneously The tumor body impedance based on ventral aorta support of in real time monitoring and blood pressure monitoring device and method thereof.
For achieving the above object, the present invention takes techniques below scheme: a kind of tumor body impedance based on ventral aorta support And blood pressure monitoring device, it is characterised in that: this device includes overlay film frame, integrated circuit and external processing apparatus;Institute Stating integrated circuit and be arranged on outside described overlay film frame, described integrated circuit includes that energy supply module, impedance measurement pass Sensor, pressure transducer, memorizer, data processor and the first radio-frequency (RF) receiving and transmission module;Described energy supply module is used In for described integrated circuit;Described impedance measuring sensor, pressure transducer are by the impedance signal detected, blood Tube wall pressure signal is through the transmission of described memorizer to described data processor, and described data processor is by impedance signal and blood Tube wall pressure signal is converted into digital signal, and loads described integrated circuit ID, timestamp information, by described first Digital signal is transferred to described external processing apparatus through described overlay film frame by radio-frequency (RF) receiving and transmission module, complete DATA REASONING, Signal emission function.
Further, described overlay film frame is used for carrying out energy and signal transmission as antenna, and it is by inner membrance, rack body Constitute with adventitia, be positioned at described rack body and be internally provided with described inner membrance, be positioned at outside described rack body and be provided with Described adventitia.
Further, described rack body includes plural bracing structure and more than one longitudinal support structure, Each described bracing structure is bent to form ring support by a tinsel, and all described ring supports are the most successively Arrange and be fixedly connected into one by longitudinal support structure described between ring support described in adjacent two.
Further, described ring support uses sinusoidal configuration, and described longitudinal support structure is fixedly installed on all described Ring support side, described longitudinal support structure is made up of another tinsel.
Further, described ring support uses sawtooth waveforms structure, all described ring supports and all described longitudinal bracings Structure uses same one metal wire to work out.
Further, resonant frequency f of described rack body:
1 f = C 1 N + C 2 n + C 3 l ,
In formula, N be the quantity of ring support, n be the fluctuating quantity of waveform in ring support, l be longitudinal support structure Length, C1、C2And C3It is positive coefficient.
Further, described integrated circuit uses string configuration, and strip integrated circuit is axial arranged along overlay film frame.
Further, described integrated circuit uses square structure or loop configuration, is wrapped in described collection when using square structure The biological compatibility shell becoming circuit external uses circular configuration;When using loop configuration, annular integrated circuit place is put down Face is parallel with the tangent plane of overlay film frame.
Further, described external processing apparatus includes launching antenna, reception antenna, the second radio-frequency (RF) receiving and transmission module, process Device, transport module and work station;By described integrated in described transmitting sky alignment body of described second radio-frequency (RF) receiving and transmission module Circuit transmission electromagnetic transmission energy, the resistance that the described integrated circuit simultaneously and in described reception antenna receiving body sends Antinoise signal and blood vessel wall pressure signal;Described second radio-frequency (RF) receiving and transmission module is by the impedance signal received and blood vessel wall pressure Signal sends to described work station through described processor, transport module.
A kind of monitoring method based on above-mentioned monitoring device, it is characterised in that the method comprises the following steps: 1) arrange One includes impedance measuring sensor, pressure transducer, data processor, the first radio-frequency (RF) receiving and transmission module and external treatment The monitoring device of equipment, wherein, external processing apparatus include reception antenna, the second radio-frequency (RF) receiving and transmission module, processor, Transport module and work station;2) impedance measuring sensor and pressure transducer gather between abdominal aortic aneurysm and overlay film frame Impedance signal, blood vessel wall pressure signal by transmitting after data processor processes to the first radio-frequency (RF) receiving and transmission module, first Radio-frequency (RF) receiving and transmission module to receive impedance signal and blood vessel wall pressure signal be modulated after be sent at outside by antenna Reason equipment;3) impedance signal received and blood vessel wall pressure signal are carried out by reception antenna through the second radio-frequency (RF) receiving and transmission module It is sent to work station after demodulation and after the process of treated device, completes monitoring.
Due to the fact that and take above technical scheme, it has the advantage that 1, due to the fact that and take real-time self-service inspection The mode surveyed, patient can understand self health status whenever and wherever possible without going to hospital, convenient and swift.2, compared to Detecting tumor by conventional diagnostic modes such as radiographies, the present invention is from radiation, and due to abdomen actively in the past Arteries and veins tumor patient suffers from renal dysfunction the most simultaneously, carries out the contrast agent of input during radiography and is likely to cause patient's kidney merit Can deteriorate and even result in renal failure, therefore instant invention overcomes the time manpower caused when existing radiography mode detects internal hemorrhage due to trauma Material resources cost height the problem that patient health situation is constituted a serious threat.3, the present invention can implant at operative treatment Impedance and blood vessel wall pressure detecting integrated circuit is implanted, it is to avoid the misery of patient's second operation while support.The present invention Can extensively apply in the status monitoring of abdominal aortic aneurysm.
Accompanying drawing explanation
Fig. 1 is the monitoring device principle schematic of the present invention;
Fig. 2 is structural representation during data processor employing NRF51822 chip in integrated circuit of the present invention;
Fig. 3 is the external equipment principle schematic of the present invention;
Fig. 4 is the antenna structure view of the sine wave shape of the present invention.
Detailed description of the invention
Below in conjunction with accompanying drawing, the present invention is carried out detailed description.It should be appreciated, however, that being provided only more of accompanying drawing Understanding the present invention well, they should not be interpreted as limitation of the present invention.
Why electrical impedance technology can rebuild the electrical parameter distribution within biological tissue, comes from biological tissue and has electricity Magnetism characteristic.For human body, the main source of various electrical characteristics and electrical activity be biomacromolecule, particle, water and The electrology characteristic of the free electron of a small amount of transient state and motion thereof produce.Research shows, not only the electricity between normal structure Characteristic is big especially, and the electrical characteristics difference between organism normal structure and pathological tissues is the biggest.According to state foreign minister The measurement result of the fibromyoma of Mus is found after the fibromyoma of Mus occurs by pass personnel, the dielectric constant of malignant tumor The highest with conductivity.But it is as the growth of tumor, dielectric constant and electrical conductivity not change significantly.When bigger Tumor when occurring internal downright bad, the change of dielectric constant and electrical conductivity is the least after frequency is higher than 0.5GHz.
As it is shown in figure 1, the present invention provides a kind of tumor body impedance based on ventral aorta support and blood pressure monitoring device, its Including an overlay film frame, an integrated circuit and an external processing apparatus.
Overlay film frame is used for carrying out energy and signal transmission as antenna, and it is made up of inner membrance, rack body and adventitia, It is positioned at rack body and is internally provided with inner membrance, be positioned at outside rack body and be provided with adventitia.
Integrated circuit is arranged on outside overlay film frame, can be installed on adventitia by integrated circuit, it is also possible to by integrated electricity Road is placed between overlay film frame and tumor body independent of support.This integrated circuit includes energy supply module, impedance measurement Sensor, pressure transducer, memorizer, data processor and the first radio-frequency (RF) receiving and transmission module.Energy supply module is through sky Line is received by the first radio-frequency (RF) receiving and transmission module and is radiated to internal electromagnetic wave by external processing apparatus, by less radio-frequency energy The mode that amount is collected is that on integrated circuit, miscellaneous part is powered.Impedance measuring sensor, pressure transducer will detect Impedance signal, the stored device of blood vessel wall pressure signal transmit to data processor, and data processor is by impedance signal and blood Tube wall pressure signal is converted into digital signal, and loads the information such as integrated circuit ID, timestamp, is received by the first radio frequency Send out module by digital signal through antenna transmission to external processing apparatus, complete DATA REASONING, signal emission function.Wherein, Energy supply module can also use minicell as an alternative, in order to directly powers for each parts on integrated circuit.
In a preferred embodiment, as in figure 2 it is shown, data processor can use and be produced by NORDIC company NRF51822 chip.This chip ADC switched pins J6 connects impedance measuring sensor, and VDD power pins J1 connects Energy supply module, XC1, XC2 pin J37-J38 connects clock circuit, VDD_PA, ANT1, ANT2 pin J30-J32 Connect the first radio-frequency (RF) receiving and transmission module.P0.01 pin J5 connects power sense circuit, P0.03-P0.07 pin J7-J11 Connecting pressure transducer, DEC1 pin J39 is through the 3rd electric capacity C3 ground connection;Ground connection after VSS pin J33, J34 parallel connection, Energy supply module is connected, between AVDD pin with VSS pin in parallel the after VSS pin J33, J34 parallel connection Four electric capacity C4.DEC2 pin J29 is ground connection after the tenth electric capacity C10 and EXP_GND pin J49 is connected;VSS pin J13 ground connection, SWCLK pin is through the 3rd resistance R3 ground connection.
Wherein, clock circuit includes the first electric capacity C1, the second electric capacity C2 and crystal oscillator X1, and crystal oscillator X1 controls end pin 1 Through the second electric capacity C2 ground connection, crystal oscillator X1 outfan pin 2 is through the first electric capacity C1 ground connection;Crystal oscillator X1 controls end pin The 1 XC1 pin J37 being additionally coupled to NRF51822 chip, crystal oscillator X1 outfan pin 2 is additionally coupled to NRF51822 The XC2 pin J38 of chip.
Power sense circuit includes the first resistance R1, the second resistance R2 and electric capacity C13, and the first resistance R1 mono-terminates height Level (i.e. energy supply module), the first resistance R1 other end is through the second resistance R2 ground connection;It is positioned at the second resistance R2 Two ends are parallel with between electric capacity C13, and the first resistance R1 other end and the second resistance R2 and are connected to by wire The P0.01 pin J5 of NRF51822 chip.
In above-described embodiment, as it is shown on figure 3, external processing apparatus includes launching antenna, reception antenna, the second radio frequency Transceiver module, processor, transport module and work station.By the collection in the second radio-frequency (RF) receiving and transmission module emitted sky alignment body Become circuit transmission electromagnetic transmission energy, simultaneously and the impedance signal that sends of the integrated circuit that is received in antenna receiving body With blood vessel wall pressure signal;Second radio-frequency (RF) receiving and transmission module is by treated to the impedance signal received and blood vessel wall pressure signal Device, transport module send to work station, in case follow-up use.Wherein, work station can use smart mobile phone, intelligence The mobile terminals such as wrist-watch.
In a preferred embodiment, being provided with signal processing system in work station, signal processing system is according to setting Measure, in time, the resistance value obtained and blood vessel wall force value judges aortic aneurysm thrombosis situation, if in the time of setting Internal impedance value and blood vessel wall force value beyond preset range, are then judged as that abdominal aortic aneurysm is still continuing hypertrophy, do not press Expect normal thrombosis;If within setting time internal impedance value and blood vessel wall force value are in preset range, then sentenced Break as the normal thrombosis of abdominal aortic aneurysm, the most gradually in atrophy.
In a preferred embodiment, as shown in Figure 4, rack body includes plural bracing structure 1 With more than one longitudinal support structure 2, each bracing structure 1 is bent to form ring support by a tinsel, All ring supports longitudinally set gradually and connect by a longitudinal support structure 2 is fixing between adjacent two ring supports Integral.
In above-described embodiment, ring support can use sinusoidal configuration or sawtooth waveforms structure.When ring support is just using During string wave structure, longitudinal support structure 2 is fixedly installed on all ring support sides, now this longitudinal support structure 2 It is made up of another tinsel;When ring support uses sawtooth waveforms structure, all ring supports and all longitudinal bracings knot Structure 2 uses same one metal wire to work out.
In above-described embodiment, all bracing structures 1 and longitudinal support structure 2 all can use Nitinol, doctor It is made with materials such as rustless steels.
In above-described embodiment, resonant frequency f of rack body:
1 f = C 1 N + C 2 n + C 3 l
In formula, N be the quantity of ring support, n be the fluctuating quantity of waveform in ring support, l be longitudinal support structure 2 Length, C1、C2And C3It is positive coefficient.Wherein, N, n and l are the biggest, and resonant frequency is the least.During use, by In can not the size of adjusting pole main body, so by adjusting rising of waveform in quantity N of ring support, ring support Length l of voltage amount n and longitudinal support structure 2 carrys out adjusting pole main body as resonant frequency during antenna.
In a preferred embodiment, integrated circuit external is enclosed with biological compatibility shell, biological compatibility Shell is avoided that the rejection producing human body.Preferably, biological compatibility shell has certain pliability, can be curved Bent.The material of biological compatibility shell preferably employs polydimethylsiloxane (PDMS).During making, can be by integrated electricity Road is put in a mold, is filled with encapsulation with polydimethylsiloxane, prepares the integrated of band biological compatibility shell Circuit.
Integrated circuit is by flexible PCB and is formed on this flexible PCB each modular circuit chip system being made up of wafer Become, to adapt to volumetric constraint, and can be curved with the change of overlay film frame shape, but its length is propped up less than overlay film Frame length, its sectional area is less than 2mm × 1mm.
Integrated circuit uses string configuration, and strip integrated circuit is axial arranged along overlay film frame.
Integrated circuit uses square structure, is wrapped in its outside biological compatibility shell and uses circular configuration.
Integrated circuit uses loop configuration, and annular integrated circuit place plane is parallel with the tangent plane of overlay film frame.
Based on said apparatus, the present invention also provides for a kind of tumor body impedance based on ventral aorta support and monitoring of blood pressure method. Impedance based on endovascular stent for abdominal aorta and the monitoring of blood pressure using the present invention is described in detail below by specific embodiment The detailed process that the impedance of abdominal aortic aneurysms, blood vessel wall pressure are monitored by device:
1, impedance measuring sensor and pressure transducer gather the impedance signal between abdominal aortic aneurysm and overlay film frame respectively With blood vessel wall pressure signal, and by transmitting after data processor processes to the first radio-frequency (RF) receiving and transmission module, the first radio frequency is received Send out module to receive impedance signal and blood vessel wall pressure signal be modulated after be sent to external processing apparatus by antenna.
2, the impedance signal received and blood vessel wall pressure signal are demodulated by reception antenna through the second radio-frequency (RF) receiving and transmission module Rear and treated device is sent to work station after processing.
In a particular embodiment, use the present invention's to detect abdominal aortic aneurysm thrombosis situation based on impedance and blood pressure measurement Device process that endovascular stent for abdominal aorta duty is detected:
The signal processing system being arranged in work station will receive abdominal aortic aneurysm and overlay film frame between resistance value, Blood vessel wall force value and preset value compare and judge aortic aneurysm thrombosis situation, if setting time internal impedance value With blood vessel wall force value beyond preset range, then it is judged as that abdominal aortic aneurysm is still continuing hypertrophy, abnormal by expection Thrombosis;If within setting time internal impedance value and blood vessel wall force value are in preset range, being then judged as abdomen master The normal thrombosis of aneurysm, the most gradually in atrophy.Furthermore it is possible to according to the resistance value of aortic aneurysm obtained and blood The thrombosis situation of aortic aneurysm is judged further by tube wall force value as reference value.
The various embodiments described above are merely to illustrate the present invention, and the structure of the most each parts, connected mode and processing technology etc. are all Can be varied from, every equivalents carried out on the basis of technical solution of the present invention and improvement, the most should not Get rid of outside protection scope of the present invention.

Claims (10)

1. a tumor body impedance based on ventral aorta support and blood pressure monitoring device, it is characterised in that: this device includes Overlay film frame, integrated circuit and external processing apparatus;Described integrated circuit is arranged on outside described overlay film frame, described Integrated circuit include energy supply module, impedance measuring sensor, pressure transducer, memorizer, data processor and First radio-frequency (RF) receiving and transmission module;Described energy supply module is used for as described integrated circuit;Described impedance measurement senses The impedance signal detected, blood vessel wall pressure signal are transmitted to described data by device, pressure transducer through described memorizer Processor, impedance signal and blood vessel wall pressure signal are converted into digital signal, and load described by described data processor Integrated circuit ID, timestamp information, passed digital signal through described overlay film frame by described first radio-frequency (RF) receiving and transmission module It is passed to described external processing apparatus, completes DATA REASONING, signal emission function.
2. tumor body impedance based on ventral aorta support as claimed in claim 1 and blood pressure monitoring device, its feature exists In: described overlay film frame is used for carrying out energy and signal transmission as antenna, and it is by inner membrance, rack body and adventitia structure Become, be positioned at described rack body and be internally provided with described inner membrance, be positioned at outside described rack body and be provided with described adventitia.
3. tumor body impedance based on ventral aorta support as claimed in claim 2 and blood pressure monitoring device, its feature exists In: described rack body includes plural bracing structure and more than one longitudinal support structure, Mei Yisuo State bracing structure and be bent to form ring support by a tinsel, all described ring supports longitudinally set gradually, And it is fixedly connected into one by longitudinal support structure described between ring support described in adjacent two.
4. tumor body impedance based on ventral aorta support as claimed in claim 3 and blood pressure monitoring device, its feature exists In: described ring support uses sinusoidal configuration, and described longitudinal support structure is fixedly installed on all described ring supports Side, described longitudinal support structure is made up of another tinsel.
5. tumor body impedance based on ventral aorta support as claimed in claim 3 and blood pressure monitoring device, its feature exists In: described ring support uses sawtooth waveforms structure, all described ring supports and all described longitudinal support structure to use Same one metal wire is worked out.
6. tumor body impedance based on ventral aorta support as claimed in claim 2 or claim 3 and blood pressure monitoring device, it is special Levy and be: resonant frequency f of described rack body:
1 f = C 1 N + C 2 n + C 3 l ,
In formula, N be the quantity of ring support, n be the fluctuating quantity of waveform in ring support, l be longitudinal support structure Length, C1、C2And C3It is positive coefficient.
7. tumor body impedance based on ventral aorta support as claimed in claim 1 and blood pressure monitoring device, its feature exists In: described integrated circuit uses string configuration, and strip integrated circuit is axial arranged along overlay film frame.
8. tumor body impedance based on ventral aorta support as claimed in claim 1 and blood pressure monitoring device, its feature exists In: described integrated circuit uses square structure or loop configuration, is wrapped in outside described integrated circuit when using square structure The biological compatibility shell in portion uses circular configuration;Annular integrated circuit place plane and overlay film when using loop configuration The tangent plane of support is parallel.
9. tumor body impedance based on ventral aorta support as claimed in claim 1 and blood pressure monitoring device, its feature exists In: described external processing apparatus includes launching antenna, reception antenna, the second radio-frequency (RF) receiving and transmission module, processor, transmission Module and work station;Launched by described second radio-frequency (RF) receiving and transmission module described integrated circuit in described transmitting sky alignment body Electromagnetic transmission energy, impedance signal that the described integrated circuit simultaneously and in described reception antenna receiving body sends and Blood vessel wall pressure signal;Described second radio-frequency (RF) receiving and transmission module by the impedance signal received and blood vessel wall pressure signal through institute State processor, transport module sends to described work station.
10. one kind based on the monitoring method of monitoring device as described in any one of claim 1 to 9, it is characterised in that The method comprises the following steps:
1) arrange one and include impedance measuring sensor, pressure transducer, data processor, the first radio-frequency (RF) receiving and transmission module With the monitoring device of external processing apparatus, wherein, external processing apparatus include reception antenna, the second radio-frequency (RF) receiving and transmission module, Processor, transport module and work station;
2) impedance measuring sensor and pressure transducer gather the impedance signal between abdominal aortic aneurysm and overlay film frame, blood Tube wall pressure signal transmits to the first radio-frequency (RF) receiving and transmission module, the first radio-frequency (RF) receiving and transmission module pair by after data processor processes The impedance signal received and blood vessel wall pressure signal are sent to external processing apparatus by antenna after being modulated;
3) impedance signal received and blood vessel wall pressure signal are demodulated by reception antenna through the second radio-frequency (RF) receiving and transmission module Rear and treated device is sent to work station after processing, and completes monitoring.
CN201610394051.6A 2016-06-06 2016-06-06 Tumor impedance and blood pressure monitoring device based on abdominal aorta stent and method based on tumor impedance and blood pressure monitoring device Pending CN105919559A (en)

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Application publication date: 20160907