CN105902933A - Chinese medicinal preparation for treating insomnia - Google Patents

Chinese medicinal preparation for treating insomnia Download PDF

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Publication number
CN105902933A
CN105902933A CN201610351972.4A CN201610351972A CN105902933A CN 105902933 A CN105902933 A CN 105902933A CN 201610351972 A CN201610351972 A CN 201610351972A CN 105902933 A CN105902933 A CN 105902933A
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China
Prior art keywords
insomnia
poria cocos
chinese medicine
medicine preparation
fructus amomi
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CN201610351972.4A
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Chinese (zh)
Inventor
宿峰
宿兆颜
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INNER MONGOLIA ZHONG'AN RHEUMATOID ARTHRITIS HOSPITAL CO Ltd
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INNER MONGOLIA ZHONG'AN RHEUMATOID ARTHRITIS HOSPITAL CO Ltd
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Priority to CN201610351972.4A priority Critical patent/CN105902933A/en
Publication of CN105902933A publication Critical patent/CN105902933A/en
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/185Magnoliopsida (dicotyledons)
    • A61K36/72Rhamnaceae (Buckthorn family), e.g. buckthorn, chewstick or umbrella-tree
    • A61K36/725Ziziphus, e.g. jujube
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/06Fungi, e.g. yeasts
    • A61K36/07Basidiomycota, e.g. Cryptococcus
    • A61K36/076Poria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/899Poaceae or Gramineae (Grass family), e.g. bamboo, corn or sugar cane
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K36/00Medicinal preparations of undetermined constitution containing material from algae, lichens, fungi or plants, or derivatives thereof, e.g. traditional herbal medicines
    • A61K36/18Magnoliophyta (angiosperms)
    • A61K36/88Liliopsida (monocotyledons)
    • A61K36/906Zingiberaceae (Ginger family)
    • A61K36/9064Amomum, e.g. round cardamom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/20Pills, tablets, discs, rods
    • A61K9/2004Excipients; Inactive ingredients

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  • Health & Medical Sciences (AREA)
  • Natural Medicines & Medicinal Plants (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Mycology (AREA)
  • Engineering & Computer Science (AREA)
  • Alternative & Traditional Medicine (AREA)
  • Biotechnology (AREA)
  • Botany (AREA)
  • Medical Informatics (AREA)
  • Microbiology (AREA)
  • Medicines Containing Plant Substances (AREA)

Abstract

The invention discloses a Chinese medicinal preparation for treating insomnia caused by deficiency of both heart and spleen. The Chinese medicinal preparation is prepared from semen ziziphi spinosae, amomum, poria cocos and lophantherum gracile. The semen ziziphi spinosae, amomum, poria cocos and lophantherum gracile are medicinal and edible articles published by the health ministry. The Chinese medicinal preparation for treating insomnia caused by deficiency of both heart and spleen is capable of overcoming the defects of the prior art, and is good in treatment effect, low in cost, short in treatment course and free from toxic or side effect.

Description

A kind of Chinese medicine preparation treating insomnia
Invention field
The present invention relates to treat a kind of Chinese medicine preparation treating the insomnia that the insufficiency of heart and spleen causes, belong to The field of Chinese medicines.
Background technology
Insomnia, i.e. sleep disorder, show as difficulty falling asleep, the most discontinuous, and too early Waking up in ground, can not be further continued for sleeping, do not have enough sleep after waking up, malaise, and burnout is felt, many Because health condition is the best, pain, doing not feel like oneself, circadian rhythm is disturbed, and sleep environment affects Deng, also there is fearness sleep to have a sleepless night.Can take appropriate measures according to different reasons.Insomnia It is due to feelings will, diet internal injury, or after being ill and old, insufficiency of natural endowment, the cause of disease such as have a guilty consicence, Cause the mind to lose to support or confused and worried, thus cause often obtaining what ortho was characterized One class illness.Mainly show as the length of one's sleep, the deficiency of the degree of depth and can not dispelling fatigue, extensive Complex power and energy, the lighter's difficulty falling asleep, or sleep but not soundly, sometimes sleeping and sometimes waking, or wake up after can not Sleep again, heavy then be insomnia all night.Insomnia is one of common clinical disease, though being not belonging to critical illness, But hinder people's normal life, work, learn and healthy, and can increase the weight of or induce palpitaition, chest The illnesss such as numbness, dizziness, headache, apoplexy.Insomnia, brings long-term misery to patient, very To the dependence formed sleeping medicine, and the sleeping medicine of long-term taking can cause iatrogenic disease. Therefore, the improvement on treatment of insomnia patients medicine is the problem needing solution at present badly.
Chinese medical discrimination: type of deficiency of both the heart and spleen insomnia is because nutrient QI and blood being insufficient, it is impossible to support the mind, causes Make confused and worried, and be difficult to fall asleep after giving birth to insomnia, dreaminess, waking up;The deficiency of blood can not go up flourish in face, So lustreless complexion and sallow;Palpitaition, nervous, god's equal insufficiency of vital energy and blood tired, weak as;Spleen The deficiency of vital energy then distastes for food, dysfunction of the spleen then abdominal distention after meal, stomach Qi weakness then do not feel like eating, or drink Food reduces;Tongue is light, arteries and veins delays weak, is the deficiency of vital energy, few the levying of blood.This type patient mostly is and worked with one's mind Degree, sad hematozemia, or woman uterine bleeding is with the passing of time, postpartum loses blood, patient body decline or row Post operation with And old deficiency of vital energy blood is few etc., causes insufficiency of vital energy and blood, be difficult to support the mind and cause to be insomnia.Some diseases People's then improper diet and overtiredness injures taste, disorder of stomach-energy, and spleen sun is not transported, and food is few indigestion and loss of appetite, qi and blood metaplasia Source deficiency, is difficult to nourish heart, and causes the insufficiency of heart and spleen.Say in " Jing Yue's complete work is insomnia ": " naivete and the person of being insomnia, must the deficiency of ying blood, seek main blood, the deficiency of blood is then difficult to nourish heart, and has a guilty conscience then Have ants in one's pants.
Summary of the invention
In place of it is an object of the invention to overcome the deficiencies in the prior art, it is provided that a kind of result for the treatment of Good, expense is low, short treating period, and the treatment of no side effects is caused insomnia by insufficiency of heart and spleen disease Medicine pill.
It is an object of the present invention to provide a kind for the treatment of and caused insomnia by insufficiency of heart and spleen disease Chinese medicine preparation, it is made up of spina date seed, fructus amomi, Poria cocos, lophatherum gracile.Wherein spina date seed, sand Benevolence, Poria cocos and the lophatherum gracile Ministry of Public Health announce integration of drinking and medicinal herbs article.
Especially, spina date seed is Semen Ziziphi Spinosae (parched).
Wherein, the weight of traditional Chinese medicine ingredients used is: spina date seed 15-45, fructus amomi 4-10, Poria cocos 5-15, lophatherum gracile 5-10.
Wherein, the Weight Preferred Ingredient ratio of traditional Chinese medicine ingredients used is: spina date seed 25-35, fructus amomi 4-8, Poria cocos 7-13, lophatherum gracile 6-10.
It is highly preferred that spina date seed 30, fructus amomi 6, Poria cocos 10, lophatherum gracile 8.
It is monarch drug in a prescription that compatibility of the present invention reuses Semen Ziziphi Spinosae (parched).By traditional Chinese medical science monarch, minister, the prescription helping, make Principle minister, with fructus amomi, Poria cocos, lophatherum gracile, plays effect of tonifying heart and spleen, nourishing blood and tranquilization altogether.
The concrete effect of each taste Chinese medicine used and effect are as follows,
Semen Ziziphi Spinosae (parched) has antitoxic heart-soothing and sedative;Nourishing the liver;Effect of arrest sweating." herbal classic is met former ": acid Jujube kernel, ripe, restrain seminal fluid, therefore treat that insomnia due to insufficiency of the gallbladder-qi, the card of polydipsia abnormal sweating;It is raw then lead abnormal heat, Therefore treat gallbladder-heat and sleep well, the card of coma burnout.By this acid of wild jujube, property is received, its benevolence then Gan Run and property Temperature, can dissipate liver, courage two through stagnant, therefore " herbal classic " controls trusted subordinate's fever and chills, and perverse trend knot is poly-, aches Blood-arthralgia etc. card all give birth to use, with thin profit liver, spleen blood vessels also.Lid liver void then cloudy wound and vexatious, no Intrinsic energy soul, must not put and sleep also.Typhoid fever dysphoria hidrosis, and empty people's night sweat, all fry with it, always Get and hold back the body fluid of liver spleen also.
Fructus amomi has dampness elimination appetizing;In promoting the circulation of qi width;Warming spleen and stopping diarrha;Antiabortive effect.Book on Chinese herbal medicine is asked Very ": contracting sand, for tune stomach key medicine of being amusing.It says tune stomach of being amusing, in fast controlled atmosphere, then in stomachache It is meritorious that ruffian is swollen, enters large intestine then effective in red dysentery of rushing down in vain, enters lung and then manage in cough with dyspnea gram.To cloud Pain relieving is antiabortive, and throat ability to speak superficial heat can disappear, gentle suitable meaning in being also.Poria cocos has excreting dampness Li Shui;Strengthening the spleen and stomach;Effect of antitoxic heart-soothing and sedative." Chinese medicinal herbal ": antitoxic heart-soothing and sedative." medicine Change justice ": PORIA ALBA, taste is only sweet light, sweet, can mend, light, can ooze, and sweet light dependent territory, by benefit Spleen is cloudy, soil Wang Shengjin, benefit of holding concurrently lung qi.Cure mainly incoordination between the spleen and the stomach, abdominal distension of having loose bowels, the inverse gas of the chest side of body, Troubled thoughts dysphoria, nausea pacifies less, and soul startles, and diaphragm asks mental disorder.Cover sweet benefit then spleen to be benefited, in Gas both and, then body fluid is given birth in vain, and mouth Jiao's tongue is done polydipsia and also solved.Control the inferior again portion damp and hot, drench scrofula oedema, Just dark urine, waist navel is unfavorable, stops storing evil water.Covering light oozing, bladder must be supported, and kidney qi is the most prosperous, then Between waist navel, blood is from profit, and road, Tianjin is popular, benefit lung in Shang Yuan, tonifying spleen in middle part, make the gas of spleen lung from Upper along under, regulating fluid apssage, with defeated bladder, therefore urine is many and can stop, puckery and energy is sharp.
Lophatherum gracile has clearing heat and relieving fidgetness, the effect of diuresis of promoting the production of body fluid." medicineization justice ": " henon bamboo Leaf, the saturating heart of delicate fragrance, the cool heat of micro-hardship, smell is the most clear.Through saying: control Wen Yiqing, specially clear away heart-fire gas, Lightly seasoned profit key, makes the heart channel of Hang-Shaoyin warm blood decompose.Cure mainly hot summer weather to quench one's thirst, feverish chest phlegm, typhoid fever dysphoria, Cough inverse syndrome characterized by dyspnea, be all good dose also.”
Chinese medical discrimination: type of deficiency of both the heart and spleen insomnia is because nutrient QI and blood being insufficient, it is impossible to support the mind, causes Make confused and worried, and be difficult to fall asleep after giving birth to insomnia, dreaminess, waking up;The deficiency of blood can not go up flourish in face, So lustreless complexion and sallow;Palpitaition, nervous, god's equal insufficiency of vital energy and blood tired, weak as;Spleen The deficiency of vital energy then distastes for food, dysfunction of the spleen then abdominal distention after meal, stomach Qi weakness then do not feel like eating, or drink Food reduces;Tongue is light, arteries and veins delays weak, is the deficiency of vital energy, few the levying of blood.This type patient mostly is and worked with one's mind Degree, sad hematozemia, or woman uterine bleeding is with the passing of time, postpartum loses blood, patient body decline or row Post operation with And old deficiency of vital energy blood is few etc., causes insufficiency of vital energy and blood, be difficult to support the mind and cause to be insomnia.Some diseases People's then improper diet and overtiredness injures taste, disorder of stomach-energy, and spleen sun is not transported, and food is few indigestion and loss of appetite, qi and blood metaplasia Source deficiency, is difficult to nourish heart, and causes the insufficiency of heart and spleen.Say in " Jing Yue's complete work is insomnia ": " naivete and the person of being insomnia, must the deficiency of ying blood, seek main blood, the deficiency of blood is then difficult to nourish heart, and has a guilty conscience then Have ants in one's pants.Therapy: tonifying heart and spleen, nourishing blood and tranquilization.
Form of Chinese drug of the present invention can be formulation well known in the art, such as pill, tablet, glue Wafer etc..
Especially, the preparation method of medicine pill of the present invention is: take Semen Ziziphi Spinosae (parched), fructus amomi, Fu Siberian cocklebur, lophatherum gracile respectively with drip washing, dry standby.Upper four tastes, choose clean medicinal material, by routine High pressure steam sterilization cabinet sterilizing, be dried, be ground into fine powder, mixing, pill, be dried, select ball, Packaging prepares pill.
Detailed description of the invention
Below by way of the description of detailed description of the invention, the invention will be further described, but this is not Being limitation of the present invention, those skilled in the art, according to the basic thought of the present invention, can do Go out various amendment or improvement, but without departing from the basic thought of the present invention, all in the present invention Within the scope of.
Embodiment 1
The pill of the insomnia that a kind for the treatment of is caused by the insufficiency of heart and spleen: weigh Semen Ziziphi Spinosae (parched) 20g, Fructus amomi 5g, Poria cocos 8g, lophatherum gracile 8g respectively with running water drip washing, dry standby.Upper four tastes, Choose clean medicinal material, with conventional high pressure steam sterilization cabinet sterilizing, be dried, be ground into fine powder, mixed Even, pill, it is dried, selects ball, packaging to prepare pill.
Embodiment 2
The pill of the insomnia that a kind for the treatment of is caused by the insufficiency of heart and spleen: weigh spina date seed 15g, fructus amomi 10g, Poria cocos 5g, lophatherum gracile 10g respectively with running water drip washing, dry standby.Upper four tastes, Choose clean medicinal material, with conventional high pressure steam sterilization cabinet sterilizing, be dried, be ground into fine powder, mixed Even, pill, it is dried, selects ball, packaging to prepare pill.
Embodiment 3
The pill of the insomnia that a kind for the treatment of is caused by the insufficiency of heart and spleen: weigh Semen Ziziphi Spinosae (parched) 30g, sand Benevolence 10g, Poria cocos 10g, lophatherum gracile 5g respectively with running water drip washing, dry standby.Upper four tastes, Choose clean medicinal material, with conventional high pressure steam sterilization cabinet sterilizing, be dried, be ground into fine powder, mixed Even, pill, it is dried, selects ball, packaging to prepare pill.
Embodiment 4
The pill of the insomnia that a kind for the treatment of is caused by the insufficiency of heart and spleen: weigh Semen Ziziphi Spinosae (parched) 30g, sand Benevolence 6g, Poria cocos 10g, lophatherum gracile 8g respectively with running water drip washing, dry standby.Upper four Taste, chooses clean medicinal material, with conventional high pressure steam sterilization cabinet sterilizing, be dried, be ground into fine powder, Mixing, pill, be dried, select ball, packaging prepare pill.
Clinical data
Over 5 years, there are the insomnia that the insufficiency of heart and spleen causes, treatment with the treatment of above-described embodiment proportioning 1200 example out-patients, the male sex 558 example in 1200 example patients, female 642 example, the age is at 18-60 Year, 45 years old mean age.The course of disease up to 3 years, the shortest is three months, average six months. Symptom and sign are shown in that differential diagnosis in tcm belongs to the insufficiency of heart and spleen.Disease is seen: cardinal symptom had palpitation, forgetful, Insomnia, dreaminess, anorexia, abdominal distension, loose stool, burnout, face is yellow, tongue is white, arteries and veins is thin.
Methods for the treatment of
The medicine pill of the oral present invention, the course for the treatment of is 30-90 days.Every 10 weight 1.2g
Instructions of taking: oral, a 3-4g, 3 times on the one.
Criterion of therapeutical effect
Effective: symptom and sign all disappears
It is effective: symptom and sign major part disappears or alleviates,
It is invalid: symptom and sign is not improved,
Result for the treatment of
Effective 787 examples, are 65.58%;Effective 379 examples, 31.58%;Invalid 34 examples, It is 2.84%;Total effective rate is 97.16%.
Model case:
Zhang, women, 45 years old, white collar.[main suit] has a sleepless night 1 year.[present illness history] is suffered from Person started insomnia, difficulty falling asleep every night, dreaming often and waking easily before 2 years, be difficult to again fall asleep after waking up. The nervous palpitaition of companion, weak god is tired, distastes for food, lusterless complexion.Without cough and expectoration, without abdominal distension Stomachache, nothing heating chilly etc..[physical examination] BP:125/85mmHg, HR:85 time/ Point, rule is neat.Mind is clear, and spirit can.No positive sign.Pale tongue, arteries and veins is thin and delicate.[auxiliary Checking] rabat, electrocardiogram, Abdominal B type ultrasonography etc. are the most not different from.[tcm diagnosis] is insomnia [traditional Chinese medical science Card type] insufficiency of heart and spleen.
Treatment: the medicine pill of the oral present invention, 30 days.
Give with above-mentioned therapy 30 days after symptom be clearly better, continue to take medicine 30 days, patient Ke An The heart is fallen asleep.Pay a return visit after 1 year and do not recur.

Claims (6)

1. treating a Chinese medicine preparation for insomnia, it is by spina date seed, fructus amomi, Poria cocos, henon bamboo Leaf is made.
A kind of Chinese medicine preparation treating insomnia the most according to claim 1, the most by weight Spina date seed 15-45, fructus amomi 4-10, Poria cocos 5-15, lophatherum gracile 5-10.
A kind of Chinese medicine preparation treating insomnia the most according to claim 2, the most by weight Spina date seed 25-35, fructus amomi 4-8, Poria cocos 7-13, lophatherum gracile 6-10.
A kind of Chinese medicine preparation treating insomnia the most according to claim 3, the most by weight Spina date seed 30, fructus amomi 6, Poria cocos 10, lophatherum gracile 8.
5. according to the Chinese medicine preparation of the arbitrary described treatment insomnia of claim 1-4, wherein acid Jujube kernel is Semen Ziziphi Spinosae (parched).
6. the preparation side of the Chinese medicine preparation having a sleepless night according to the arbitrary described treatment of claim 1-5 Method, its step includes: take Semen Ziziphi Spinosae (parched), fructus amomi, Poria cocos, lophatherum gracile respectively with drip washing, dry in the air Dry standby;Upper four tastes, choose clean medicinal material, with conventional high pressure steam sterilization cabinet sterilizing, be dried, Be ground into fine powder, mixing, pill, be dried, select ball, packaging prepare pill.
CN201610351972.4A 2016-05-24 2016-05-24 Chinese medicinal preparation for treating insomnia Pending CN105902933A (en)

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Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110638945A (en) * 2019-09-26 2020-01-03 宁波德康生物制品有限公司 Nerve-soothing and sleep-aiding substitutional tea and preparation method thereof
CN111358907A (en) * 2020-04-28 2020-07-03 赖宇 Medicinal and edible traditional Chinese medicine formula granule for treating insomnia and preparation method thereof

Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101653579A (en) * 2009-05-20 2010-02-24 北京国奥健康科技研究院 Traditional Chinese medicine preparation for treating intractable insomnia
CN101732627A (en) * 2009-12-30 2010-06-16 西安谦坤投资咨询有限公司 Chinese medicinal composition for treating insomnia and preparation method thereof
CN102370832A (en) * 2011-11-17 2012-03-14 中国中医科学院中医临床基础医学研究所 Chinese medicinal compound preparation for treating insomnia and preparation method thereof
CN103099944A (en) * 2013-01-15 2013-05-15 南阳医学高等专科学校 Drug for treating stubborn insomnia
CN103933222A (en) * 2014-04-18 2014-07-23 詹霞 Traditional Chinese medicine for treating insomnia
CN105497632A (en) * 2015-12-30 2016-04-20 叶尉 Chinese medicinal preparation for treat insomnia

Patent Citations (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN101653579A (en) * 2009-05-20 2010-02-24 北京国奥健康科技研究院 Traditional Chinese medicine preparation for treating intractable insomnia
CN101732627A (en) * 2009-12-30 2010-06-16 西安谦坤投资咨询有限公司 Chinese medicinal composition for treating insomnia and preparation method thereof
CN102370832A (en) * 2011-11-17 2012-03-14 中国中医科学院中医临床基础医学研究所 Chinese medicinal compound preparation for treating insomnia and preparation method thereof
CN103099944A (en) * 2013-01-15 2013-05-15 南阳医学高等专科学校 Drug for treating stubborn insomnia
CN103933222A (en) * 2014-04-18 2014-07-23 詹霞 Traditional Chinese medicine for treating insomnia
CN105497632A (en) * 2015-12-30 2016-04-20 叶尉 Chinese medicinal preparation for treat insomnia

Cited By (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CN110638945A (en) * 2019-09-26 2020-01-03 宁波德康生物制品有限公司 Nerve-soothing and sleep-aiding substitutional tea and preparation method thereof
CN111358907A (en) * 2020-04-28 2020-07-03 赖宇 Medicinal and edible traditional Chinese medicine formula granule for treating insomnia and preparation method thereof

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